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searching for Nature Chemical Biology 452 found (486 total)

Nicholas Turner (chemist) (1,057 words) [view diff] exact match in snippet view article

O’Reilly, Elaine (2013). "Biocatalytic retrosynthesis" (PDF). Nature Chemical Biology. 9 (5): 285–288. doi:10.1038/nchembio.1235. PMID 23594772. Retrieved

Gideon Davies (1,873 words) [view diff] exact match in snippet view article find links to article

Cowtan, Kevin (2015). "Carbohydrate anomalies in the PDB" (PDF). Nature Chemical Biology. 11 (5): 303. doi:10.1038/nchembio.1798. PMID 25885951. Agirre

Chemically induced dimerization (947 words) [view diff] exact match in snippet view article find links to article

logic gating with a gibberellin-induced dimerization system". Nature Chemical Biology. 8 (5): 465–70. doi:10.1038/nchembio.922. PMC 3368803. PMID 22446836

SLC45A4 (235 words) [view diff] exact match in snippet view article find links to article

identifies a pathway required for paraquat-induced cell death". Nature Chemical Biology. 13 (12): 1274–1279. doi:10.1038/nchembio.2499. PMC 5698099. PMID 29058724

Radical SAM enzymes (6,104 words) [view diff] exact match in snippet view article find links to article

methyltransferase expands the chemistry of radical SAM enzymes". Nature Chemical Biology. 8 (12): 957–959. doi:10.1038/nchembio.1091. PMID 23064318. Mahanta

Chemical Probes Portal (1,371 words) [view diff] exact match in snippet view article find links to article

et al. (August 2015). "The promise and peril of chemical probes". Nature Chemical Biology. 11 (8): 536–41. doi:10.1038/nchembio.1867. PMC 4706458. PMID 26196764

YcaO (428 words) [view diff] exact match in snippet view article find links to article

to activate amide backbones during peptide cyclodehydrations". Nature Chemical Biology. 8 (6): 569–575. doi:10.1038/nchembio.944. PMC 3428213. PMID 22522320

Shikimate kinase (440 words) [view diff] exact match in snippet view article find links to article

and functional dynamics of the pentafunctional AROM complex". Nature Chemical Biology. 16 (9): 973–978. doi:10.1038/s41589-020-0587-9. PMID 32632294

Molecular Frontiers Foundation (368 words) [view diff] exact match in snippet view article find links to article

three year period. Kotz, Joanne (2007). "Molecular Frontiers". Nature Chemical Biology. 3 (2): 79. doi:10.1038/nchembio0207-79. PMID 17235339. "Molecular

Daniel Nomura (1,230 words) [view diff] exact match in snippet view article find links to article

vacuolar H+-ATPase activates autophagy via mTORC1 inhibition". Nature Chemical Biology. 15 (8): 776–785. doi:10.1038/s41589-019-0308-4. ISSN 1552-4469

Christopher Chang (938 words) [view diff] exact match in snippet view article find links to article

peroxide produced for cell signaling : Abstract : Nature Chemical Biology". Nature Chemical Biology. 3 (5): 263–267. doi:10.1038/nchembio871. PMID 17401379

Bioretrosynthesis (419 words) [view diff] exact match in snippet view article find links to article

"Bioretrosynthetic construction of a didanosine biosynthetic pathway". Nature Chemical Biology. 10: 392–399. doi:10.1038/nchembio.1494. PMC 4017637. PMID 24657930

20S-Hydroxycholesterol (355 words) [view diff] exact match in snippet view article find links to article

"Oxysterols are allosteric activators of the oncoprotein Smoothened". Nature Chemical Biology. 8 (2): 211–220. doi:10.1038/nchembio.765. PMC 3262054. PMID 22231273

Structural Genomics Consortium (5,316 words) [view diff] exact match in snippet view article find links to article

access chemical and clinical probes to support drug discovery". Nature Chemical Biology. 5 (7): 436–440. doi:10.1038/nchembio0709-436. ISSN 1552-4469.

Thymine-DNA glycosylase (1,613 words) [view diff] exact match in snippet view article find links to article

glycosylase specifically recognizes 5-carboxylcytosine-modified DNA". Nature Chemical Biology. 8 (4): 328–30. doi:10.1038/nchembio.914. PMC 3307914. PMID 22327402

Polyene antimycotic (462 words) [view diff] exact match in snippet view article find links to article

"Amphotericin forms an extramembranous and fungicidal sterol sponge". Nature Chemical Biology. 10 (5): 400–406. doi:10.1038/nchembio.1496. PMC 3992202. PMID 24681535

O-GlcNAc (14,334 words) [view diff] exact match in snippet view article find links to article

Occurs Cotranslationally to Stabilize Nascent Polypeptide Chains". Nature Chemical Biology. 11 (5): 319–25. doi:10.1038/nchembio.1774. PMID 25774941. Lazarus

Product (chemistry) (1,064 words) [view diff] exact match in snippet view article

biology: lessons from the history of synthetic organic chemistry". Nature Chemical Biology. 3 (9): 521–525. doi:10.1038/nchembio0907-521. PMID 17710092. S2CID 17719341

GPER (3,997 words) [view diff] exact match in snippet view article find links to article

biomolecular screening converge on a selective agonist for GPR30". Nature Chemical Biology. 2 (4): 207–212. doi:10.1038/nchembio775. PMID 16520733. S2CID 2364534

Succinylation (215 words) [view diff] exact match in snippet view article find links to article

lysine succinylation as a new post-translational modification". Nature Chemical Biology. 7 (1): 58–63. doi:10.1038/nchembio.495. PMC 3065206. PMID 21151122

Reactive sulfur species (120 words) [view diff] exact match in snippet view article find links to article

species for signaling by hydrogen sulfide oxidation pathways". Nature Chemical Biology. 11 (7): 457–464. doi:10.1038/nchembio.1834. PMC 4818113. PMID 26083070

BET inhibitor (2,514 words) [view diff] exact match in snippet view article find links to article

kinase-bromodomain inhibitors for rationally designed polypharmacology". Nature Chemical Biology. 10 (4): 305–12. doi:10.1038/nchembio.1471. PMC 3998711. PMID 24584101

Gary Siuzdak (2,655 words) [view diff] exact match in snippet view article find links to article

"Metabolic oxidation regulates embryonic stem cell differentiation". Nature Chemical Biology. 6 (6): 411–417. doi:10.1038/nchembio.364. ISSN 1552-4469. PMC 2873061

Quantitative proteomics (3,409 words) [view diff] exact match in snippet view article find links to article

2005). "Mass spectrometry-based proteomics turns quantitative". Nature Chemical Biology. 1 (5): 252–62. doi:10.1038/nchembio736. PMID 16408053. S2CID 32054251

Lipidology (1,236 words) [view diff] exact match in snippet view article find links to article

(May 2022). "Lipid metabolism in T cell signaling and function". Nature Chemical Biology. 18 (5): 470–481. doi:10.1038/s41589-022-01017-3. ISSN 1552-4469

AlkB (1,337 words) [view diff] exact match in snippet view article find links to article

nuclear RNA is a major substrate of the obesity-associated FTO". Nature Chemical Biology. 7 (12): 885–887. doi:10.1038/nchembio.687. PMC 3218240. PMID 22002720

Judit Puskas (381 words) [view diff] exact match in snippet view article find links to article

explores and exploits the heterogeneity of natural biopolymers". Nature Chemical Biology. 6: 697. doi:10.1038/nchembio.449. PMID 20852603. "Judit E. Puskas

Stuart Schreiber (3,391 words) [view diff] exact match in snippet view article find links to article

journals have been introduced (Cell Chemical Biology, ChemBioChem, Nature Chemical Biology, ACS Chemical Biology]) to cover the field. Schreiber has been

James A. Wells (2,043 words) [view diff] exact match in snippet view article find links to article

ligase specificity by proteomic identification of ligation sites". Nature Chemical Biology. 14 (1): 50–57. doi:10.1038/nchembio.2521. ISSN 1552-4469. PMC 5726896

N6-Methyladenosine (5,629 words) [view diff] exact match in snippet view article find links to article

complex mediates mammalian nuclear RNA N6-adenosine methylation". Nature Chemical Biology. 10 (2): 93–95. doi:10.1038/nchembio.1432. PMC 3911877. PMID 24316715

Methazolamide (274 words) [view diff] exact match in snippet view article find links to article

inhibition ameliorates tau toxicity via enhanced tau secretion". Nature Chemical Biology: 1–11. doi:10.1038/s41589-024-01762-7. PMID 39482469. Iyer GR,

Elizabeth Sattely (796 words) [view diff] exact match in snippet view article find links to article

catalyze S-heterocyclizations in cabbage phytoalexin biosynthesis". Nature Chemical Biology. 11 (11): 837–839. doi:10.1038/nchembio.1914. ISSN 1552-4450. PMC 4731101

Nucleotide sugar (903 words) [view diff] exact match in snippet view article find links to article

drive the equilibria of glycosyltransferase-catalyzed reactions". Nature Chemical Biology. 7 (10): 685–91. doi:10.1038/nchembio.638. PMC 3177962. PMID 21857660

Glycorandomization (1,507 words) [view diff] exact match in snippet view article find links to article

a natural-product glycosyltransferase by directed evolution". Nature Chemical Biology. 3 (10): 657–62. doi:10.1038/nchembio.2007.28. PMID 17828251. Zhang

Bing Liu (scientist) (783 words) [view diff] exact match in snippet view article

Susceptibility of Macrophages and Microglia to Ferroptotic Death," Nature Chemical Biology, 16:2780-290 (2020). doi: 10.1038/s41589-019-0462-8 S Thermozier

Molecular binding (1,405 words) [view diff] exact match in snippet view article find links to article

docking of large libraries for the discovery of chemical probes". Nature Chemical Biology. 10 (12): 1066–72. doi:10.1038/nchembio.1666. PMC 4232467. PMID 25344815

Mitragynine pseudoindoxyl (737 words) [view diff] exact match in snippet view article find links to article

signaling profiles of the µOR activated by diverse agonists". Nature Chemical Biology. 19 (4): 423–430. doi:10.1038/s41589-022-01208-y. PMC 11098091

Gq alpha subunit (1,092 words) [view diff] exact match in snippet view article find links to article

"Inactive-state preassembly of Gq-coupled receptors and Gq heterotrimers". Nature Chemical Biology. 7 (11): 740–747. doi:10.1038/nchembio.642. PMC 3177959. PMID 21873996

Arachidonate 5-lipoxygenase inhibitor (1,292 words) [view diff] exact match in snippet view article find links to article

insights into 5-lipoxygenase inhibition by natural products". Nature Chemical Biology. 16 (7): 783–790. doi:10.1038/s41589-020-0544-7. ISSN 1552-4450

Cycloprop-2-ene carboxylic acid (198 words) [view diff] exact match in snippet view article find links to article

(2009). "Identification of the toxic trigger in mushroom poisoning". Nature Chemical Biology. 5 (7): 465–7. doi:10.1038/nchembio.179. PMID 19465932.

Therapeutic effect (968 words) [view diff] exact match in snippet view article find links to article

biology and combination therapy in the quest for clinical efficacy". Nature Chemical Biology. 2 (9): 458–466. doi:10.1038/nchembio817. ISSN 1552-4450. PMID 16921358

Monoacylglycerol lipase (965 words) [view diff] exact match in snippet view article find links to article

2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects". Nature Chemical Biology. 5 (1): 37–44. doi:10.1038/nchembio.129. PMC 2605181. PMID 19029917

Aclarubicin (337 words) [view diff] exact match in snippet view article find links to article

the genome with anti-cancer drugs defines target specificities". Nature Chemical Biology. 11 (7): 472–480. doi:10.1038/nchembio.1811. PMID 25961671. v t

MKNK2 (834 words) [view diff] exact match in snippet view article find links to article

potentiates β-cell regeneration via translational regulation". Nature Chemical Biology. 18 (9): 942–953. doi:10.1038/s41589-022-01047-x. PMC 7613404.

Perry A. Frey (351 words) [view diff] exact match in snippet view article find links to article

1038/nchembio0809-534. PMID 19620990. Goodman, Catherine (2009). "Perry Frey". Nature Chemical Biology. 5 (8): 534. doi:10.1038/nchembio0809-534. ISSN 1552-4469. PMID 19620990

Heteromer (1,397 words) [view diff] exact match in snippet view article find links to article

"Building a new conceptual framework for receptor heteromers". Nature Chemical Biology. 5 (3): 131–4. doi:10.1038/nchembio0309-131. PMC 2681085. PMID 19219011

Chemical probe (159 words) [view diff] exact match in snippet view article find links to article

PE, et al. (2015). "The promise and peril of chemical probes". Nature Chemical Biology. 11 (8): 536–41. doi:10.1038/nchembio.1867. PMC 4706458. PMID 26196764

Ro07-5220 (204 words) [view diff] exact match in snippet view article find links to article

receptor models identify new benzodiazepine binding-site ligands". Nature Chemical Biology. 8 (5): 455–64. doi:10.1038/nchembio.917. PMC 3368153. PMID 22446838

Phosphoserine (505 words) [view diff] exact match in snippet view article find links to article

genetic encoding of phosphoserine and its nonhydrolyzable analog". Nature Chemical Biology. 11 (7): 496–503. doi:10.1038/nchembio.1823. PMC 4830402. PMID 26030730

N,N-Dimethylsphingosine (168 words) [view diff] exact match in snippet view article find links to article

altered sphingolipids in chronic pain of neuropathic origin". Nature Chemical Biology. 8: 232–234. doi:10.1038/nchembio.767. PMC 3567618. PMID 22267119

GPRC5A (905 words) [view diff] exact match in snippet view article find links to article

reveals microbiota-derived aromatic monoamine agonists for GPRC5A". Nature Chemical Biology. 19 (10): 1205–1214. doi:10.1038/s41589-023-01328-z. PMID 37248411

Post-translational modification (3,140 words) [view diff] exact match in snippet view article find links to article

paralog PoxA modifies elongation factor-P with (R)-β-lysine". Nature Chemical Biology. 7 (10): 667–9. doi:10.1038/nchembio.632. PMC 3177975. PMID 21841797

National Centre for Biological Sciences (652 words) [view diff] exact match in snippet view article find links to article

"RETRACTED ARTICLE: Discovery of iron-sensing bacterial riboswitches". Nature Chemical Biology. 17 (8): 924. doi:10.1038/s41589-020-00665-7. PMID 33020663. S2CID 222137628

Expanded genetic code (9,132 words) [view diff] exact match in snippet view article find links to article

phosphorylation with a genetically encoded photocaged amino acid". Nature Chemical Biology. 3 (12): 769–72. doi:10.1038/nchembio.2007.44. PMID 17965709. Palei

Nirmatrelvir (2,009 words) [view diff] exact match in snippet view article find links to article

inhibitors and activity-based probes for patient-sample imaging". Nature Chemical Biology. 17 (2): 222–228. doi:10.1038/s41589-020-00689-z. PMID 33093684

Hippuristanol (161 words) [view diff] exact match in snippet view article find links to article

characterization of IRESes by an inhibitor of the RNA helicase eIF4A". Nature Chemical Biology. 2 (4): 213–220. doi:10.1038/nchembio776. PMID 16532013. S2CID 15635690

Palmitoleoylation (273 words) [view diff] exact match in snippet view article find links to article

Hannoush, Rami N. (February 2016). "Fatty acylation of Wnt proteins". Nature Chemical Biology. 12 (2): 60–69. doi:10.1038/nchembio.2005. ISSN 1552-4469. PMID 26784846

Aerolysin (294 words) [view diff] exact match in snippet view article find links to article

Horizontal gene transfer from prokaryotes to eukaryotes" (PDF). Nature Chemical Biology. 9 (6460): 623–629. doi:10.1038/nchembio.1312. PMID 23912165. This

Mechanism of action (1,865 words) [view diff] exact match in snippet view article find links to article

and mechanism of action in chemical biology and drug discovery". Nature Chemical Biology. 9 (4): 232–240. doi:10.1038/nchembio.1199. ISSN 1552-4450. PMC 5543995

Upstream open reading frame (418 words) [view diff] exact match in snippet view article find links to article

of short open reading frame-encoded peptides in human cells". Nature Chemical Biology. 9 (1): 59–64. doi:10.1038/nchembio.1120. PMC 3625679. PMID 23160002

Norbinaltorphimine (517 words) [view diff] exact match in snippet view article find links to article

of inverse agonism via κ-opioid receptor-G protein complexes". Nature Chemical Biology. doi:10.1038/s41589-024-01812-0. PMID 39775170. Takemori AE, Ho

Glycosyltransferase (1,566 words) [view diff] exact match in snippet view article find links to article

drive the equilibria of glycosyltransferase-catalyzed reactions". Nature Chemical Biology. 7 (10): 685–91. doi:10.1038/nchembio.638. PMC 3177962. PMID 21857660

Sulfoquinovosyl diacylglycerol (568 words) [view diff] exact match in snippet view article find links to article

that cleaves sulfoquinovosyl diacylglyceride sulfolipids" (PDF). Nature Chemical Biology. 12 (4): 215–217. doi:10.1038/nchembio.2023. PMID 26878550.

PHF8 (926 words) [view diff] exact match in snippet view article find links to article

2008). "Expanding chemical biology of 2-oxoglutarate oxygenases". Nature Chemical Biology. 4 (3): 152–6. doi:10.1038/nchembio0308-152. PMID 18277970. Loenarz

Xanthine oxidase (1,932 words) [view diff] exact match in snippet view article find links to article

reductase that regulates nitrite and nitric oxide homeostasis". Nature Chemical Biology. 4 (7): 411–7. doi:10.1038/nchembio.92. PMID 18516050. Hemilä H

Febrifugine (187 words) [view diff] exact match in snippet view article find links to article

other febrifugine derivatives inhibit prolyl-tRNA synthetase". Nature Chemical Biology. 8 (3): 311–317. doi:10.1038/nchembio.790. PMC 3281520. PMID 22327401

Decoy receptors (685 words) [view diff] exact match in snippet view article find links to article

'decoy receptor' effectively silences the Gas6-Axl signaling axis". Nature Chemical Biology. 10 (11): 977–983. doi:10.1038/nchembio.1636. PMC 4372605. PMID 25242553

Neamine transaminase (198 words) [view diff] exact match in snippet view article find links to article

pathways of kanamycin biosynthesis allows antibiotic manipulation". Nature Chemical Biology. 7 (11): 843–52. doi:10.1038/nchembio.671. PMID 21983602. Neamine+transaminase

Derek Lowe (chemist) (829 words) [view diff] exact match in snippet view article

et al. (August 2015). "The promise and peril of chemical probes". Nature Chemical Biology. 11 (8): 536–41. doi:10.1038/nchembio.1867. PMC 4706458. PMID 26196764

Phosphonoacetaldehyde reductase (NADH) (117 words) [view diff] exact match in snippet view article

the biosynthesis of the antibiotic phosphinothricin tripeptide". Nature Chemical Biology. 3 (8): 480–5. doi:10.1038/nchembio.2007.9. PMC 4313788. PMID 17632514

1,4-Dichlorobenzene (927 words) [view diff] exact match in snippet view article find links to article

para-dichlorobenzene suppress apoptosis in Caenorhabditis elegans". Nature Chemical Biology. 2 (6): 338–345. doi:10.1038/nchembio791. PMID 16699520. S2CID 18402091

Agmatidine (1,119 words) [view diff] exact match in snippet view article find links to article

in a tRNA anticodon is essential for AUA decoding in archaea". Nature Chemical Biology. 6 (4): 277–282. doi:10.1038/nchembio.323. PMID 20139989. Hendrickson

Cysteine sulfinic acid (304 words) [view diff] exact match in snippet view article find links to article

proteomics reveals new targets of cysteine sulfinic acid reductase". Nature Chemical Biology. 14 (11): 995–1004. doi:10.1038/s41589-018-0116-2. PMC 6192846

Paul Schimmel (1,143 words) [view diff] exact match in snippet view article find links to article

2013). "Essential nontranslational functions of tRNA synthetases". Nature Chemical Biology. 9 (3): 145–153. doi:10.1038/nchembio.1158. PMC 3773598. PMID 23416400

Enzyme Function Initiative (1,502 words) [view diff] exact match in snippet view article find links to article

(2005). "Assignment of protein function in the postgenomic era". Nature Chemical Biology. 1 (3): 130–42. doi:10.1038/nchembio0805-130. PMID 16408016. S2CID 86672970

EIF5A (1,335 words) [view diff] exact match in snippet view article find links to article

of translation elongation factor EF-P is hydroxylated by YfcM". Nature Chemical Biology. 8 (8): 695–697. doi:10.1038/nchembio.1001. PMID 22706199. Rossi

Hydrogenase (4,191 words) [view diff] exact match in snippet view article find links to article

along the substrate tunnel and oxygen sensitivity in hydrogenase". Nature Chemical Biology. 6 (1): 63–70. doi:10.1038/nchembio.276. PMID 19966788. Greening

Gražvydas Lukinavičius (868 words) [view diff] exact match in snippet view article find links to article

extended groups from synthetic cofactors by DNA methyltransferases. Nature Chemical Biology 2, 31-2. (cited 252 times) Lukinavičius, G., C. Blaukopf, E. Pershagen

Acyl-protein thioesterase (1,460 words) [view diff] exact match in snippet view article find links to article

"Small-molecule inhibition of APT1 affects Ras localization and signaling". Nature Chemical Biology. 6 (6): 449–56. doi:10.1038/nchembio.362. PMID 20418879. Duncan

Twister sister ribozyme (874 words) [view diff] exact match in snippet view article find links to article

self-cleaving ribozymes revealed by comparative genomics analysis". Nature Chemical Biology. 11 (8): 606–10. doi:10.1038/nchembio.1846. PMC 4509812. PMID 26167874

Christopher T. Walsh (556 words) [view diff] exact match in snippet view article find links to article

Donk, Wilfred A (2005). "The protein modification repertoire". Nature Chemical Biology. 1 (5). Springer Science and Business Media LLC: 243. doi:10

Andreas Matouschek (402 words) [view diff] exact match in snippet view article find links to article

Matouschek, Andreas (2009). "Targeting proteins for degradation". Nature Chemical Biology. 5 (11): 815–22. doi:10.1038/nchembio.250. PMC 4228941. PMID 19841631

Hyperthermophile (2,052 words) [view diff] exact match in snippet view article find links to article

"Rethinking glycolysis: on the biochemical logic of metabolic pathways". Nature Chemical Biology. 8 (6): 509–517. doi:10.1038/nchembio.971. ISSN 1552-4450. PMID 22596202

Glycine receptor (1,542 words) [view diff] exact match in snippet view article find links to article

glycine receptors contributes to cannabis-induced analgesia". Nature Chemical Biology. 7 (5): 296–303. doi:10.1038/nchembio.552. PMC 3388539. PMID 21460829

Heterotrimeric G protein (1,237 words) [view diff] exact match in snippet view article find links to article

preassembly of G(q)-coupled receptors and G(q) heterotrimers". Nature Chemical Biology. 7 (10): 740–7. doi:10.1038/nchembio.642. PMC 3177959. PMID 21873996

Fuzzy complex (1,914 words) [view diff] exact match in snippet view article find links to article

machines take shape in eukaryotic transcriptional regulation". Nature Chemical Biology. 4 (12): 728–37. doi:10.1038/nchembio.127. PMC 2921704. PMID 19008886

Vorinostat (1,442 words) [view diff] exact match in snippet view article find links to article

activity restores function to misfolded CFTR in cystic fibrosis". Nature Chemical Biology. 6 (1): 25–33. doi:10.1038/nchembio.275. PMC 2901172. PMID 19966789

Codeine 3-O-demethylase (100 words) [view diff] exact match in snippet view article find links to article

O-demethylation steps of morphine biosynthesis in opium poppy". Nature Chemical Biology. 6 (4): 273–5. doi:10.1038/nchembio.317. PMID 20228795. Codeine+3-O-demethylase

Michelle Chang (biochemist) (740 words) [view diff] exact match in snippet view article

for production of functionalized terpenoids using plant P450s". Nature Chemical Biology. 3 (5): 274–277. doi:10.1038/nchembio875. ISSN 1552-4469. PMID 17438551

Beat Fierz (1,158 words) [view diff] exact match in snippet view article find links to article

ubiquitylation disrupts local and higher-order chromatin compaction". Nature Chemical Biology. 7 (2): 113–119. doi:10.1038/nchembio.501. PMC 3078768. PMID 21196936

Thebaine 6-O-demethylase (97 words) [view diff] exact match in snippet view article find links to article

O-demethylation steps of morphine biosynthesis in opium poppy". Nature Chemical Biology. 6 (4): 273–5. doi:10.1038/nchembio.317. PMID 20228795. Thebaine+6-O-demethylase

Adenosine monophosphate (1,255 words) [view diff] exact match in snippet view article find links to article

2011). "AMP-activated protein kinase: nature's energy sensor". Nature Chemical Biology. 7 (8): 512–8. doi:10.1038/nchembio.610. PMID 21769098. Faubert

Yi Tang (biochemist) (572 words) [view diff] exact match in snippet view article

2015). "Minimum Information about a Biosynthetic Gene cluster". Nature Chemical Biology. 11 (9): 625–631. doi:10.1038/nchembio.1890. PMC 5714517. PMID 26284661

Diarylquinoline (309 words) [view diff] exact match in snippet view article find links to article

"Diarylquinolines target subunit c of mycobacterial ATP synthase". Nature Chemical Biology. 3 (6): 323–324. doi:10.1038/nchembio884. ISSN 1552-4450. PMID 17496888

Comamonas testosteroni (606 words) [view diff] exact match in snippet view article find links to article

a Comamonas platform for diverse aromatic carbon metabolism". Nature Chemical Biology. 19 (5): 651–662. doi:10.1038/s41589-022-01237-7. ISSN 1552-4469

Bonnie Sloane (605 words) [view diff] exact match in snippet view article find links to article

protease activity with fluorescently quenched activity-based probes". Nature Chemical Biology. 1 (4): 203–209. doi:10.1038/nchembio728. ISSN 1552-4450. PMID 16408036

Dek Woolfson (1,309 words) [view diff] exact match in snippet view article find links to article

Woolfson, Derek N. (August 2010). "n → π * interactions in proteins". Nature Chemical Biology. 6 (8): 615–620. doi:10.1038/nchembio.406. ISSN 1552-4469. PMC 2921280

Proteoform (221 words) [view diff] exact match in snippet view article find links to article

et al. (February 2018). "How many human proteoforms are there?". Nature Chemical Biology. 14 (3): 206–214. doi:10.1038/nchembio.2576. PMC 5837046. PMID 29443976

Bioconjugation (4,669 words) [view diff] exact match in snippet view article find links to article

2011). "Choosing an effective protein bioconjugation strategy". Nature Chemical Biology. 7 (12): 876–884. doi:10.1038/nchembio.720. PMID 22086289. Tilley

VVD-118313 (183 words) [view diff] exact match in snippet view article find links to article

of JAK1 targeting an isoform-restricted allosteric cysteine". Nature Chemical Biology. 18 (12): 1388–1398. doi:10.1038/s41589-022-01098-0. PMC 7614775

Cross-link (1,797 words) [view diff] exact match in snippet view article find links to article

"Inactive-state preassembly of Gq-coupled receptors and Gq heterotrimers". Nature Chemical Biology. 7 (11): 740–747. doi:10.1038/nchembio.642. PMC 3177959. PMID 21873996

RNA-targeting small molecule drugs (4,401 words) [view diff] exact match in snippet view article find links to article

modulators enhance U1–pre-mRNA association and rescue SMA mice". Nature Chemical Biology. 11 (7): 511–7. doi:10.1038/nchembio.1837. PMID 26030728. Roy,

Tyrosine kinase inhibitor (1,179 words) [view diff] exact match in snippet view article find links to article

inhibitors block protein kinase recruitment to the Hsp90-Cdc37 system". Nature Chemical Biology. 9 (5): 307–312. doi:10.1038/nchembio.1212. PMC 5695660. PMID 23502424

Orthogonality (2,686 words) [view diff] exact match in snippet view article find links to article

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Arginine deiminase (415 words) [view diff] exact match in snippet view article find links to article

cyanobacterial ornithine-ammonia cycle involves an arginine dihydrolase". Nature Chemical Biology. 14 (6): 575–581. doi:10.1038/s41589-018-0038-z. PMID 29632414

Delftia (620 words) [view diff] exact match in snippet view article find links to article

biomineralization by a metallophore from a gold-associated microbe". Nature Chemical Biology. 9 (4): 241–243. doi:10.1038/nchembio.1179. ISSN 1552-4469. PMID 23377039

Periplasm (2,287 words) [view diff] exact match in snippet view article find links to article

insight into the formation of lipoprotein-β-barrel complexes". Nature Chemical Biology. 16 (9): 1019–1025. doi:10.1038/s41589-020-0575-0. PMC 7610366

Carbonyl cyanide m-chlorophenyl hydrazone (516 words) [view diff] exact match in snippet view article find links to article

(2017). "The pharmacological regulation of cellular mitophagy". Nature Chemical Biology. 13 (2): 136–146. doi:10.1038/nchembio.2287. PMID 28103219. Retrieved

LY294002 (442 words) [view diff] exact match in snippet view article find links to article

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Structure-based combinatorial protein engineering (465 words) [view diff] exact match in snippet view article find links to article

landscape separating divergent plant sesquiterpene synthases". Nature Chemical Biology. 4 (10): 617–23. doi:10.1038/nchembio.113. PMC 2664519. PMID 18776889

Directed evolution (4,761 words) [view diff] exact match in snippet view article find links to article

designed retro-aldolase leads to complete active site remodeling". Nature Chemical Biology. 9 (8): 494–8. doi:10.1038/nchembio.1276. PMC 3720730. PMID 23748672

Adenozil-chloride synthase (110 words) [view diff] exact match in snippet view article find links to article

characterization of a marine bacterial SAM-dependent chlorinase". Nature Chemical Biology. 4 (1): 69–74. doi:10.1038/nchembio.2007.56. PMC 2762381. PMID 18059261

IDFP (437 words) [view diff] exact match in snippet view article find links to article

the endocannabinoid system by organophosphorus nerve agents". Nature Chemical Biology. 4 (6): 373–378. doi:10.1038/nchembio.86. PMC 2597283. PMID 18438404

Thiaminase (2,002 words) [view diff] exact match in snippet view article find links to article

Sun G, Begley TP (August 2007). "A new thiamin salvage pathway". Nature Chemical Biology. 3 (8): 492–7. doi:10.1038/nchembio.2007.13. PMID 17618314. Green

Alpha-enolase (1,937 words) [view diff] exact match in snippet view article find links to article

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Tripterygium wilfordii (1,165 words) [view diff] exact match in snippet view article find links to article

subunit of tFiih, is a target of the natural product triptolide". Nature Chemical Biology. 7 (3): 182–188. doi:10.1038/nchembio.522. PMC 3622543. PMID 21278739

2'-Deamino-2'-hydroxyneamine transaminase (124 words) [view diff] exact match in snippet view article find links to article

pathways of kanamycin biosynthesis allows antibiotic manipulation". Nature Chemical Biology. 7 (11): 843–52. doi:10.1038/nchembio.671. PMID 21983602.

Molecular glue (3,962 words) [view diff] exact match in snippet view article find links to article

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2-Deoxystreptamine glucosyltransferase (124 words) [view diff] exact match in snippet view article find links to article

pathways of kanamycin biosynthesis allows antibiotic manipulation". Nature Chemical Biology. 7 (11): 843–52. doi:10.1038/nchembio.671. PMID 21983602.

Synthetic immunology (767 words) [view diff] exact match in snippet view article find links to article

Commentary: Synthetic immunology to engineer human immunity". Nature Chemical Biology. 6 (12): 871–872. doi:10.1038/nchembio.477. ISSN 1552-4450. PMID 21079593

Casein kinase 2 (1,125 words) [view diff] exact match in snippet view article find links to article

phosphorylation and O-GlcNAcylation revealed by semisynthesis". Nature Chemical Biology. 8 (3): 262–269. doi:10.1038/nchembio.771. PMC 3288285. PMID 22267120

Pikromycin (555 words) [view diff] exact match in snippet view article find links to article

basis for macrolactonization by the pikromycin thioesterase". Nature Chemical Biology. 2 (10): 537–542. doi:10.1038/nchembio824. PMID 16969372. S2CID 6262508

Indican (522 words) [view diff] exact match in snippet view article find links to article

biochemical protecting group for a sustainable indigo dyeing strategy". Nature Chemical Biology. 14 (3): 256–261. doi:10.1038/nchembio.2552. PMC 5866135. PMID 29309053

Mycobacterium tuberculosis (8,269 words) [view diff] exact match in snippet view article find links to article

"Mycobacterium tuberculosis releases an antacid that remodels phagosomes". Nature Chemical Biology. 15 (9): 889–899. doi:10.1038/s41589-019-0336-0. PMC 6896213. PMID 31427817

David R. Liu (2,916 words) [view diff] exact match in snippet view article find links to article

bisubstrate-competitive Src inhibitors from DNA-templated macrocycles". Nature Chemical Biology. 8 (4): 366–74. doi:10.1038/nchembio.792. PMC 3307835. PMID 22344177

Aminopyrimidine aminohydrolase (340 words) [view diff] exact match in snippet view article find links to article

Sun G, Begley TP (August 2007). "A new thiamin salvage pathway". Nature Chemical Biology. 3 (8): 492–7. doi:10.1038/nchembio.2007.13. PMID 17618314. Jenkins

Giulio Superti-Furga (4,526 words) [view diff] exact match in snippet view article find links to article

"Global survey of the immunomodulatory potential of common drugs". Nature Chemical Biology. 13 (6): 681–690. doi:10.1038/nchembio.2360. ISSN 1552-4469. PMC 5438060

Factor D (2,047 words) [view diff] exact match in snippet view article find links to article

factor D inhibitors targeting the alternative complement pathway". Nature Chemical Biology. 12 (12): 1105–1110. doi:10.1038/nchembio.2208. PMID 27775713.

SNAP-tag (1,001 words) [view diff] exact match in snippet view article find links to article

that sulfasalazine inhibits tetrahydrobiopterin biosynthesis". Nature Chemical Biology. 7 (6): 375–383. doi:10.1038/nchembio.557. PMID 21499265. Keppler

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Pimelyl-(acyl-carrier protein) methyl ester esterase (253 words) [view diff] exact match in snippet view article

synthesis begins by hijacking the fatty acid synthetic pathway". Nature Chemical Biology. 6 (9): 682–8. doi:10.1038/nchembio.420. PMC 2925990. PMID 20693992

Bacillithiol (642 words) [view diff] exact match in snippet view article find links to article

(2009). "Bacillithiol is an antioxidant thiol produced in Bacilli". Nature Chemical Biology. 5 (9): 625–627. doi:10.1038/nchembio.189. ISSN 1552-4450. PMC 3510479

Genetically encoded voltage indicator (2,777 words) [view diff] exact match in snippet view article find links to article

evolution approach applied to fluorescent voltage reporters". Nature Chemical Biology. 14 (4): 352–360. doi:10.1038/s41589-018-0004-9. ISSN 1552-4469

Malonyl-CoA O-methyltransferase (254 words) [view diff] exact match in snippet view article find links to article

synthesis begins by hijacking the fatty acid synthetic pathway". Nature Chemical Biology. 6 (9): 682–8. doi:10.1038/nchembio.420. PMC 2925990. PMID 20693992

Junying Yuan (1,669 words) [view diff] exact match in snippet view article find links to article

cell death with therapeutic potential for ischemic brain injury". Nature Chemical Biology. 1 (2): 112–9. doi:10.1038/nchembio711. PMID 16408008. S2CID 866321

Phosphomethylpyrimidine synthase (273 words) [view diff] exact match in snippet view article find links to article

pyrimidine biosynthesis expands the radical SAM superfamily". Nature Chemical Biology. 4 (12): 758–65. doi:10.1038/nchembio.121. PMC 2587053. PMID 18953358

Purmorphamine (303 words) [view diff] exact match in snippet view article find links to article

"Purmorphamine activates the Hedgehog pathway by targeting Smoothened". Nature Chemical Biology. 2 (1): 29–30. doi:10.1038/nchembio753. PMID 16408088. S2CID 29035911

Diacylglycerol lipase (2,148 words) [view diff] exact match in snippet view article find links to article

lipid network involved in macrophage inflammatory responses". Nature Chemical Biology. 8 (12): 999–1007. doi:10.1038/nchembio.1105. ISSN 1552-4469. PMC 3513945

Christopher J. Schofield (4,207 words) [view diff] exact match in snippet view article find links to article

"Oxygenase-catalyzed ribosome hydroxylation occurs in prokaryotes and humans". Nature Chemical Biology. 8 (12): 960–962. doi:10.1038/nchembio.1093. ISSN 1552-4450. PMC 4972389

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The function of terpene natural products in the natural world. Nature Chemical Biology, 3(7), 408–414. doi:10.1038/nchembio.2007.5 Wouters, F.C., Reichelt

Romidepsin (1,459 words) [view diff] exact match in snippet view article find links to article

(March 2010). "Chemical phylogenetics of histone deacetylases". Nature Chemical Biology. 6 (3): 238–243. doi:10.1038/nchembio.313. PMC 2822059. PMID 20139990

Coenzyme A (2,526 words) [view diff] exact match in snippet view article find links to article

(October 2015). "Metabolism: Jump-starting CoA biosynthesis". Nature Chemical Biology. 11 (10): 757–758. doi:10.1038/nchembio.1912. PMID 26379022. Sibon

T7 holin family (401 words) [view diff] exact match in snippet view article find links to article

expanded genetic code on evolutionary paths to higher fitness".Nature Chemical Biology 10 (3): 178–180.doi:10.1038/nchembio.1450. PMC 3932624.PMID 24487692

Rhein (molecule) (631 words) [view diff] exact match in snippet view article

nuclear RNA is a major substrate of the obesity-associated FTO". Nature Chemical Biology. 7 (12): 885–887. doi:10.1038/nchembio.687. ISSN 1552-4450. PMC 3218240

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L; Urban, Laszlo (2010). "Fishing for neuroactive compounds". Nature Chemical Biology. 6 (3): 172–173. doi:10.1038/nchembio.320. ISSN 1552-4469. PMID 20154663

Cyclodipeptide synthases (1,371 words) [view diff] exact match in snippet view article find links to article

are a family of tRNA-dependent peptide bond-forming enzymes". Nature Chemical Biology. 5 (6): 414–420. doi:10.1038/nchembio.175. PMID 19430487. Retrieved

ABHD3 (219 words) [view diff] exact match in snippet view article find links to article

ABHD3 as a physiologic regulator of medium-chain phospholipids". Nature Chemical Biology. 7 (11): 763–5. doi:10.1038/nchembio.659. PMC 3201731. PMID 21926997

Nordihydroguaiaretic acid (639 words) [view diff] exact match in snippet view article find links to article

insights into 5-lipoxygenase inhibition by natural products". Nature Chemical Biology. 16 (7): 783–790. doi:10.1038/s41589-020-0544-7. PMC 7747934. PMID 32393899

2-Deoxystreptamine N-acetyl-D-glucosaminyltransferase (171 words) [view diff] exact match in snippet view article find links to article

pathways of kanamycin biosynthesis allows antibiotic manipulation". Nature Chemical Biology. 7 (11): 843–52. doi:10.1038/nchembio.671. PMID 21983602.

Daunorubicin (1,271 words) [view diff] exact match in snippet view article find links to article

the genome with anti-cancer drugs defines target specificities". Nature Chemical Biology. 11 (7): 472–480. doi:10.1038/nchembio.1811. PMID 25961671. Weiss

Wood-decay fungus (6,550 words) [view diff] exact match in snippet view article find links to article

Cleavage of Polysaccharides by Copper Enzymes Depends on H2O2. Nature Chemical Biology, 13(10), 1123-1128. Martinez D, Challacombe J, Morgenstern I, Hibbett

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autophagy and reduce toxicity in Huntington's disease models". Nature Chemical Biology. 3 (6): 331–338. doi:10.1038/nchembio883. PMC 2635561. PMID 17486044

Echinomycin (433 words) [view diff] exact match in snippet view article find links to article

biosynthesis of antitumor nonribosomal peptides in Escherichia coli". Nature Chemical Biology. 2 (8): 423–8. doi:10.1038/nchembio803. PMID 16799553. S2CID 40607322

Proteome (3,013 words) [view diff] exact match in snippet view article find links to article

Ge, Ying (March 2018). "How many human proteoforms are there?". Nature Chemical Biology. 14 (3): 206–214. doi:10.1038/nchembio.2576. hdl:1721.1/120977

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monitoring of protein maturation in live human cells by NMR", Nature Chemical Biology, vol. 9, issue 5 (2013). "Proteoglycan-specific molecular switch

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identify fungal secondary metabolites and their gene clusters". Nature Chemical Biology. 13 (8): 895–901. doi:10.1038/nchembio.2408. PMC 5577364. PMID 28604695

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Foundation web site MoleClues.org Kotz, Joanne (2007). "Molecular Frontiers". Nature Chemical Biology. 3 (2): 79. doi:10.1038/nchembio0207-79. PMID 17235339.

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Chemical genetics (965 words) [view diff] exact match in snippet view article find links to article

reveals an inhibitor of Dusp6 that expands cardiac cell lineages". Nature Chemical Biology. 5 (9): 680–687. doi:10.1038/nchembio.190. PMC 2771339. PMID 19578332

NLRP3 (1,736 words) [view diff] exact match in snippet view article find links to article

closes the active conformation of NLRP3 to an inactive state". Nature Chemical Biology. 15 (6): 560–564. doi:10.1038/s41589-019-0278-6. ISSN 1552-4450

X-linked intellectual disability (2,017 words) [view diff] exact match in snippet view article find links to article

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Vanadium nitrogenase (659 words) [view diff] exact match in snippet view article find links to article

structure of vanadium nitrogenase reveals an unusual bridging ligand". Nature Chemical Biology. 13 (9): 956–960. doi:10.1038/nchembio.2428. PMC 5563456. PMID 28692069

Urate oxidase (1,914 words) [view diff] exact match in snippet view article find links to article

degradation pathway through phylogenetic comparison of whole genomes". Nature Chemical Biology. 2 (3): 144–8. doi:10.1038/nchembio768. PMID 16462750. S2CID 13441301

Peptide nucleic acid (1,832 words) [view diff] exact match in snippet view article find links to article

selection and amplification system for peptide nucleic acids". Nature Chemical Biology. 6 (2): 148–55. doi:10.1038/nchembio.280. PMC 2808706. PMID 20081830

Craig M. Crews (2,879 words) [view diff] exact match in snippet view article find links to article

"Catalytic in vivo protein knockdown by small-molecule PROTACs". Nature Chemical Biology. 11 (8): 611–617. doi:10.1038/nchembio.1858. ISSN 1552-4469. PMC 4629852

Machine learning in bioinformatics (8,085 words) [view diff] exact match in snippet view article find links to article

computational framework to explore large-scale biosynthetic diversity". Nature Chemical Biology. 16 (1): 60–68. doi:10.1038/s41589-019-0400-9. PMC 6917865. PMID 31768033

Muscarinic acetylcholine receptor M5 (1,511 words) [view diff] exact match in snippet view article find links to article

preassembly of G(q)-coupled receptors and G(q) heterotrimers". Nature Chemical Biology. 7 (10): 740–7. doi:10.1038/nchembio.642. PMC 3177959. PMID 21873996

ABHD12 (1,593 words) [view diff] exact match in snippet view article find links to article

lysophosphatidylserines are regulated by ABHD16A and ABHD12 interplay". Nature Chemical Biology. 11 (2): 164–71. doi:10.1038/nchembio.1721. PMC 4301979. PMID 25580854

Boswellic acid (897 words) [view diff] exact match in snippet view article find links to article

insights into 5-lipoxygenase inhibition by natural products". Nature Chemical Biology. 16 (7): 783–790. doi:10.1038/s41589-020-0544-7. ISSN 1552-4450

Phenformin (939 words) [view diff] exact match in snippet view article find links to article

2015). "Targeting mitochondria metabolism for cancer therapy". Nature Chemical Biology. 11 (1): 9–15. doi:10.1038/nchembio.1712. PMC 4340667. PMID 25517383

Sentinel cell (607 words) [view diff] exact match in snippet view article find links to article

programmed to respond to environmental DNA including human sequences". Nature Chemical Biology. 20 (2): 211–220. doi:10.1038/s41589-023-01431-1. ISSN 1552-4469

Branaplam (496 words) [view diff] exact match in snippet view article find links to article

modulators enhance U1-pre-mRNA association and rescue SMA mice". Nature Chemical Biology. 11 (7): 511–517. doi:10.1038/nchembio.1837. PMID 26030728. "LMI070"

Squire Booker (2,365 words) [view diff] exact match in snippet view article find links to article

pyrimidine biosynthesis expands the radical SAM superfamily". Nature Chemical Biology. 4 (12): 758–765. doi:10.1038/nchembio.121. ISSN 1552-4450. PMC 2587053

Neomycin (2,173 words) [view diff] exact match in snippet view article find links to article

pathways of kanamycin biosynthesis allows antibiotic manipulation". Nature Chemical Biology. 7 (11): 843–52. doi:10.1038/nchembio.671. PMID 21983602. Kudo

Stephen J. Benkovic (3,270 words) [view diff] exact match in snippet view article find links to article

"Allosteric regulation and catalysis emerge via a common route". Nature Chemical Biology. 4 (8): 474–482. doi:10.1038/nchembio.98. ISSN 1552-4469. PMID 18641628

Enolase (3,253 words) [view diff] exact match in snippet view article find links to article

2016). "SF2312 is a natural phosphonate inhibitor of enolase". Nature Chemical Biology. 12 (12): 1053–1058. doi:10.1038/nchembio.2195. PMC 5110371. PMID 27723749

Lehman College (3,514 words) [view diff] exact match in snippet view article find links to article

carotenoid biosynthesis through a heme-based cis-trans isomerase". Nature Chemical Biology. 11 (8): 598–605. doi:10.1038/nchembio.1840. PMC 4509827. PMID 26075523

RAR-related orphan receptor gamma (2,372 words) [view diff] exact match in snippet view article find links to article

T(H)17 differentiation by generating endogenous RORγ agonists". Nature Chemical Biology. 11 (2): 141–147. doi:10.1038/nchembio.1714. PMID 25558972. Fauber

Drosocin (981 words) [view diff] exact match in snippet view article find links to article

translation inhibition by the glycosylated drosocin peptide". Nature Chemical Biology. 19 (9): 1072–1081. doi:10.1038/s41589-023-01293-7. ISSN 1552-4469

Terpene (3,491 words) [view diff] exact match in snippet view article find links to article

"Production and engineering of terpenoids in plant cell culture". Nature Chemical Biology. 3 (7): 387–395. doi:10.1038/nchembio.2007.8. ISSN 1552-4450. PMID 17576426

Threose nucleic acid (1,216 words) [view diff] exact match in snippet view article find links to article

Gregory (February 2005). "Modified nucleic acids on display". Nature Chemical Biology. Archived from the original on 4 September 2012. Retrieved 21 April

Sigma-2 receptor (2,332 words) [view diff] exact match in snippet view article find links to article

map of 20(S)-hydroxycholesterol interactors in cell membranes". Nature Chemical Biology. 17 (12): 1271–1280. doi:10.1038/s41589-021-00907-2. PMC 8607797

Sigma-2 receptor (2,332 words) [view diff] exact match in snippet view article find links to article

map of 20(S)-hydroxycholesterol interactors in cell membranes". Nature Chemical Biology. 17 (12): 1271–1280. doi:10.1038/s41589-021-00907-2. PMC 8607797

Susan Marqusee (267 words) [view diff] exact match in snippet view article find links to article

ubiquitination affects protein energetics and proteasomal degradation". Nature Chemical Biology. 16 (8): 866–875. doi:10.1038/s41589-020-0556-3. ISSN 1552-4469

Discodermia calyx (507 words) [view diff] exact match in snippet view article find links to article

from a pyrophosphate protoxin produced by a sponge symbiont". Nature Chemical Biology. 10 (8): 648–55. doi:10.1038/nchembio.1573. PMID 24974231. "Discodermia

Mary Lidstrom (658 words) [view diff] exact match in snippet view article find links to article

physiological heterogeneity in microbial population behavior. Nature Chemical Biology 6 (10) 705–712 Ludmila Chistoserdova, Marina G. Kalyuzhnaya and

Phosphonate (2,533 words) [view diff] exact match in snippet view article find links to article

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Protein disulfide-isomerase (1,936 words) [view diff] exact match in snippet view article find links to article

disulfide isomerase suppress apoptosis induced by misfolded proteins". Nature Chemical Biology. 6 (12): 900–6. doi:10.1038/nchembio.467. PMC 3018711. PMID 21079601

Muscarinic acetylcholine receptor M3 (1,761 words) [view diff] exact match in snippet view article find links to article

preassembly of G(q)-coupled receptors and G(q) heterotrimers". Nature Chemical Biology. 7 (10): 740–747. doi:10.1038/nchembio.642. PMC 3177959. PMID 21873996

Modelling biological systems (2,118 words) [view diff] exact match in snippet view article find links to article

(2008). "Learning biological networks* from modules to dynamics". Nature Chemical Biology. 4 (11): 658–664. doi:10.1038/nchembio.122. PMID 18936750. Edwards

Polypharmacology (1,159 words) [view diff] exact match in snippet view article find links to article

of dual inhibitors of tyrosine and phosphoinositide kinases". Nature Chemical Biology. 4 (11): 691–699. doi:10.1038/nchembio.117. ISSN 1552-4469. PMC 2880455

Ribonucleotide (2,619 words) [view diff] exact match in snippet view article find links to article

"Genome instability due to ribonucleotide incorporation into DNA". Nature Chemical Biology. 6 (10): 774–81. doi:10.1038/nchembio.424. PMC 2942972. PMID 20729855

G protein (2,754 words) [view diff] exact match in snippet view article find links to article

preassembly of G(q)-coupled receptors and G(q) heterotrimers". Nature Chemical Biology. 7 (10): 740–7. doi:10.1038/nchembio.642. PMC 3177959. PMID 21873996

Russula (2,646 words) [view diff] exact match in snippet view article find links to article

"Identification of the toxic trigger in mushroom poisoning". Nature Chemical Biology. 5 (7): 465–7. doi:10.1038/nchembio.179. PMID 19465932. Wang XN

Halofuginone (413 words) [view diff] exact match in snippet view article find links to article

other febrifugine derivatives inhibit prolyl-tRNA synthetase". Nature Chemical Biology. 8 (3): 311–7. doi:10.1038/nchembio.790. PMC 3281520. PMID 22327401

Enterococcus faecalis (3,039 words) [view diff] exact match in snippet view article find links to article

denaturation of a protein dimer monitored at atomic resolution". Nature Chemical Biology. 9 (4): 264–270. doi:10.1038/nchembio.1181. PMC 5521822. PMID 23396077

ADP-ribosylation (3,545 words) [view diff] exact match in snippet view article find links to article

new target residue for endogenous ADP-ribosylation on histones". Nature Chemical Biology. 12 (12): 998–1000. doi:10.1038/nchembio.2180. PMC 5113755. PMID 27723750

HaloTag (977 words) [view diff] exact match in snippet view article find links to article

general scaffold for far-red tunable chemigenetic indicators". Nature Chemical Biology. 17 (6): 718–723. doi:10.1038/s41589-021-00775-w. ISSN 1552-4469

Ursodeoxycholic acid (2,561 words) [view diff] exact match in snippet view article find links to article

pathway for a prominent class of microbiota-derived bile acids". Nature Chemical Biology. 11 (9): 685–690. doi:10.1038/nchembio.1864. PMC 4543561. PMID 26192599

Kang-Yell Choi (1,806 words) [view diff] exact match in snippet view article find links to article

of the Axin-RGS domain promotes β-catenin and Ras degradation. Nature Chemical Biology. (2016) Small molecule inhibitors of Dishevelled-CXXC5 interaction

Biological computing (2,205 words) [view diff] exact match in snippet view article find links to article

logic gating with a gibberellin-induced dimerization system". Nature Chemical Biology. 8 (5): 465–70. doi:10.1038/nchembio.922. PMC 3368803. PMID 22446836

Muscarinic acetylcholine receptor (3,165 words) [view diff] exact match in snippet view article find links to article

preassembly of G(q)-coupled receptors and G(q) heterotrimers". Nature Chemical Biology. 7 (10): 740–7. doi:10.1038/nchembio.642. PMC 3177959. PMID 21873996

Cytochrome c (3,827 words) [view diff] exact match in snippet view article find links to article

(September 2005). "Cardiolipin oxidation sets cytochrome c free". Nature Chemical Biology. 1 (4): 188–9. doi:10.1038/nchembio0905-188. PMID 16408030. S2CID 45381495

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(2017). "Engineering RGB color vision into Escherichia coli". Nature Chemical Biology. 13 (7): 706–8. doi:10.1038/nchembio.2390. PMID 28530708. Levskaya

Guanine tetrad (723 words) [view diff] exact match in snippet view article find links to article

five-guanine-tract G-quadruplex structure from the human MYC promoter". Nature Chemical Biology. 1 (3): 167–173. doi:10.1038/nchembio723. ISSN 1552-4469. PMC 4690526

Cell-free system (2,007 words) [view diff] exact match in snippet view article find links to article

for in vitro glycolysis by metabolic real-time analysis" (PDF). Nature Chemical Biology. 7 (5): 271–277. doi:10.1038/nchembio.541. PMID 21423171. S2CID 6613252

TIM barrel (4,820 words) [view diff] exact match in snippet view article find links to article

four-fold symmetric TIM-barrel protein with atomic-level accuracy". Nature Chemical Biology. 12 (1): 29–34. doi:10.1038/nchembio.1966. PMC 4684731. PMID 26595462

Enediyne (1,819 words) [view diff] exact match in snippet view article find links to article

product biosynthesis unified by a diiodotetrayne intermediate". Nature Chemical Biology. 20 (9): 1210–1219. doi:10.1038/s41589-024-01636-y. ISSN 1552-4469

Pyridoxal 5'-phosphate synthase (glutamine hydrolyzing) (447 words) [view diff] exact match in snippet view article

complex reaction coordinate of pyridoxal phosphate synthase". Nature Chemical Biology. 4 (7): 425–30. doi:10.1038/nchembio.93. PMID 18516049. Wallner

Receptor (biochemistry) (2,672 words) [view diff] exact match in snippet view article

preassembly of G(q)-coupled receptors and G(q) heterotrimers". Nature Chemical Biology. 7 (10): 740–7. doi:10.1038/nchembio.642. PMC 3177959. PMID 21873996

Aminoacyl tRNA synthetase (3,608 words) [view diff] exact match in snippet view article find links to article

2013). "Essential nontranslational functions of tRNA synthetases". Nature Chemical Biology. 9 (3): 145–53. doi:10.1038/nchembio.1158. PMC 3773598. PMID 23416400

Muscarinic acetylcholine receptor M1 (2,227 words) [view diff] exact match in snippet view article find links to article

preassembly of G(q)-coupled receptors and G(q) heterotrimers". Nature Chemical Biology. 7 (10): 740–747. doi:10.1038/nchembio.642. PMC 3177959. PMID 21873996

QX39 (230 words) [view diff] exact match in snippet view article find links to article

of chaperone-mediated autophagy by retinoic acid derivatives". Nature Chemical Biology. 9 (6): 374–82. doi:10.1038/nchembio.1230. PMC 3661710. PMID 23584676

FTO gene (3,886 words) [view diff] exact match in snippet view article find links to article

nuclear RNA is a major substrate of the obesity-associated FTO". Nature Chemical Biology. 7 (12): 885–7. doi:10.1038/nchembio.687. PMC 3218240. PMID 22002720

Hemoprotein (2,454 words) [view diff] exact match in snippet view article find links to article

tetrahelical protein design for diverse oxidoreductase functions". Nature Chemical Biology. 9 (12): 826–833. doi:10.1038/nchembio.1362. PMC 4034760. PMID 24121554

3-dehydroquinate synthase (842 words) [view diff] exact match in snippet view article find links to article

and functional dynamics of the pentafunctional AROM complex". Nature Chemical Biology. 16 (9): 973–978. doi:10.1038/s41589-020-0587-9. PMID 32632294

Farinamycin (335 words) [view diff] exact match in snippet view article find links to article

oxidase catalyzes C-nitrosation in nitrosobenzamide biosynthesis". Nature Chemical Biology. 6 (9): 641–643. doi:10.1038/nchembio.418. PMID 20676084. Sattler

Cyclophellitol (254 words) [view diff] exact match in snippet view article find links to article

in situ visualization of active glucocerebrosidase molecules’, Nature Chemical Biology. Nature Publishing Group, 6(12), pp. 907–913. doi: 10.1038/nchembio

Photoactivated peptide (945 words) [view diff] exact match in snippet view article find links to article

2009). "Augmented photoswitching modulates immune signaling". Nature Chemical Biology. 5 (10): 724–726. doi:10.1038/nchembio.214. PMID 19734911. Mart

Gregory Petsko (1,744 words) [view diff] exact match in snippet view article find links to article

"Pharmacological chaperones stabilize retromer to limit APP processing". Nature Chemical Biology. 10 (6): 443–449. doi:10.1038/nchembio.1508. ISSN 1552-4450. PMC 4076047

1,2,3-Trichloropropane (1,290 words) [view diff] exact match in snippet view article find links to article

tunnels as a strategy for degrading an anthropogenic substrate". Nature Chemical Biology. 5 (10): 727–33. doi:10.1038/nchembio.205. PMID 19701186. Yan,

Edward Boyden (3,444 words) [view diff] exact match in snippet view article find links to article

evolution approach applied to fluorescent voltage reporters". Nature Chemical Biology. 14 (4): 352–360. doi:10.1038/s41589-018-0004-9. ISSN 1552-4469

Delftia acidovorans (1,667 words) [view diff] exact match in snippet view article find links to article

biomineralization by a metallophore from a gold-associated microbe". Nature Chemical Biology. 9 (4): 241–243. doi:10.1038/nchembio.1179. ISSN 1552-4469. PMID 23377039

Cryopyrin-associated periodic syndrome (1,734 words) [view diff] exact match in snippet view article find links to article

closes the active conformation of NLRP3 to an inactive state". Nature Chemical Biology. 15 (6): 560–564. doi:10.1038/s41589-019-0278-6. ISSN 1552-4450

Neutral network (evolution) (2,832 words) [view diff] exact match in snippet view article

Karplus, M (Jun 17, 2011). "Behind the folding funnel diagram". Nature Chemical Biology. 7 (7): 401–4. doi:10.1038/nchembio.565. PMID 21685880. Tokuriki

Anna Marie Pyle (565 words) [view diff] exact match in snippet view article find links to article

molecules that target group II introns are potent antifungal agents". Nature Chemical Biology. 14 (12): 1073–1078. doi:10.1038/s41589-018-0142-0. ISSN 1552-4469

Lipid (7,366 words) [view diff] exact match in snippet view article find links to article

Feigenson GW (November 2006). "Phase behavior of lipid mixtures". Nature Chemical Biology. 2 (11): 560–563. doi:10.1038/nchembio1106-560. PMC 2685072. PMID 17051225

CRISPR gene editing (20,481 words) [view diff] exact match in snippet view article find links to article

Cas9 enables genome editing with reduced off-target activity". Nature Chemical Biology. 14 (3): 311–316. doi:10.1038/nchembio.2559. PMC 5902734. PMID 29377001

Hovlinc (344 words) [view diff] exact match in snippet view article find links to article

is a recently evolved class of ribozyme found in human lncRNA". Nature Chemical Biology. 17 (5): 601–607. doi:10.1038/s41589-021-00763-0. ISSN 1552-4469

Formic acid (3,856 words) [view diff] exact match in snippet view article find links to article

coli on formate and methanol via the reductive glycine pathway". Nature Chemical Biology. 16 (5): 538–545. doi:10.1038/s41589-020-0473-5. ISSN 1552-4469

CRISPR gene editing (20,481 words) [view diff] exact match in snippet view article find links to article

Cas9 enables genome editing with reduced off-target activity". Nature Chemical Biology. 14 (3): 311–316. doi:10.1038/nchembio.2559. PMC 5902734. PMID 29377001

Lipid (7,366 words) [view diff] exact match in snippet view article find links to article

Feigenson GW (November 2006). "Phase behavior of lipid mixtures". Nature Chemical Biology. 2 (11): 560–563. doi:10.1038/nchembio1106-560. PMC 2685072. PMID 17051225

Electric bacteria (634 words) [view diff] exact match in snippet view article find links to article

stimulates production of highly conductive microbial OmcZ nanowires". Nature Chemical Biology. 16 (10): 1136–1142. doi:10.1038/s41589-020-0623-9. ISSN 1552-4469

Hydrocodone (5,233 words) [view diff] exact match in snippet view article find links to article

biomanufacturing platform for natural and semisynthetic opioids". Nature Chemical Biology. 10 (10): 837–844. doi:10.1038/nchembio.1613. PMC 4167936. PMID 25151135

Bacterial nanowires (2,176 words) [view diff] exact match in snippet view article find links to article

stimulates production of highly conductive microbial OmcZ nanowires". Nature Chemical Biology. 16 (10): 1136–1142. doi:10.1038/s41589-020-0623-9. PMC 7502555

Ubiquitin (11,335 words) [view diff] exact match in snippet view article find links to article

reveals E2-specific ubiquitin conjugation profiles in live cells". Nature Chemical Biology. doi:10.1038/s41589-024-01809-9. PMID 39762535. Miranda M, Sorkin

Noscapine (2,714 words) [view diff] exact match in snippet view article find links to article

a protective group in noscapine biosynthesis in opium poppy". Nature Chemical Biology. 11 (2): 104–106. doi:10.1038/nchembio.1717. PMID 25485687. Kamei

Single-particle tracking (1,750 words) [view diff] exact match in snippet view article find links to article

direct measurements of protein synthesis kinetics in live cells". Nature Chemical Biology. 14 (6): 618–626. doi:10.1038/s41589-018-0063-y. ISSN 1552-4469

3-dehydroquinate dehydratase (941 words) [view diff] exact match in snippet view article find links to article

and functional dynamics of the pentafunctional AROM complex". Nature Chemical Biology. 16 (9): 973–978. doi:10.1038/s41589-020-0587-9. PMID 32632294

Bradley L. Pentelute (1,836 words) [view diff] exact match in snippet view article find links to article

automated flow-based approach for accelerated peptide synthesis". Nature Chemical Biology. 13 (5): 464–466. doi:10.1038/nchembio.2318. ISSN 1552-4450. PMID 28244989

Pesticide degradation (2,429 words) [view diff] exact match in snippet view article find links to article

efficient pathways for degradation of anthropogenic chemicals". Nature Chemical Biology. 5 (8): 559–66. doi:10.1038/nchembio.197. PMC 2867350. PMID 19620997

Erin Schuman (1,191 words) [view diff] exact match in snippet view article find links to article

(August 9, 2009). "Cell-selective metabolic labeling of proteins". Nature Chemical Biology. 5 (10): 715–717. doi:10.1038/nchembio.200. PMC 3176724. PMID 19668194

Ribonuclease T (1,158 words) [view diff] exact match in snippet view article find links to article

for RNA trimming by RNase T in stable RNA 3'-end maturation". Nature Chemical Biology. 7 (4): 236–43. doi:10.1038/nchembio.524. PMID 21317904. Li Z,

Lipid II (1,368 words) [view diff] exact match in snippet view article find links to article

allows direct assay of transpeptidase inhibition by b-lactams". Nature Chemical Biology. 13 (7): 793–798. doi:10.1038/nchembio.2388. PMC 5478438. PMID 28553948

TMPRSS2 (2,644 words) [view diff] exact match in snippet view article find links to article

of human TMPRSS2 protease implicated in SARS-CoV-2 activation". Nature Chemical Biology. 18 (9): 963–971. doi:10.1038/s41589-022-01059-7. PMID 35676539

Lactimidomycin (464 words) [view diff] exact match in snippet view article find links to article

eukaryotic translation elongation by cycloheximide and lactimidomycin". Nature Chemical Biology. 6 (3): 209–217. doi:10.1038/nchembio.304. PMC 2831214. PMID 20118940

Keiko Torii (1,245 words) [view diff] exact match in snippet view article find links to article

hijacking of auxin signaling with an engineered auxin–TIR1 pair". Nature Chemical Biology. 14 (3): 299–305. doi:10.1038/nchembio.2555. PMC 5812785. PMID 29355850

Klebsazolicin (515 words) [view diff] exact match in snippet view article find links to article

inhibits 70S ribosome by obstructing the peptide exit tunnel". Nature Chemical Biology. 13 (10): 1129–1136. doi:10.1038/nchembio.2462. PMC 5701663. PMID 28846667

Dopamine receptor D2 (3,958 words) [view diff] exact match in snippet view article find links to article

mechanism of allostery in a G protein-coupled receptor dimer". Nature Chemical Biology. 10 (9): 745–52. doi:10.1038/nchembio.1593. PMC 4138267. PMID 25108820

Scott A. Small (644 words) [view diff] exact match in snippet view article find links to article

"Pharmacological chaperones stabilize retromer to limit APP processing". Nature Chemical Biology. 10 (6): 443–449. doi:10.1038/nchembio.1508. ISSN 1552-4469. PMC 4076047

RNA (7,625 words) [view diff] exact match in snippet view article find links to article

modulators enhance U1–pre-mRNA association and rescue SMA mice". Nature Chemical Biology. 11 (7): 511–517. doi:10.1038/nchembio.1837. ISSN 1552-4450. PMID 26030728

Macromolecular assembly (2,293 words) [view diff] exact match in snippet view article find links to article

JR (August 2008). "Cooperativity in macromolecular assembly". Nature Chemical Biology. 4 (8): 458–465. doi:10.1038/nchembio.102. PMID 18641626. Perrakis

Bacteriocin (3,542 words) [view diff] exact match in snippet view article find links to article

"Sublancin is not a lantibiotic but an S-linked glycopeptide". Nature Chemical Biology. 7 (2): 78–80. doi:10.1038/nchembio.509. PMC 3060661. PMID 21196935

Squid (6,860 words) [view diff] exact match in snippet view article find links to article

protein coacervates defines the squid beak mechanical gradient". Nature Chemical Biology. 11 (7): 488–495. doi:10.1038/nchembio.1833. PMID 26053298. S2CID 205303026

Lipid-anchored protein (2,232 words) [view diff] exact match in snippet view article find links to article

"Trafficking and signaling by fatty-acylated and prenylated proteins". Nature Chemical Biology. 2 (11): 584–90. doi:10.1038/nchembio834. PMID 17051234. S2CID 9734759

Standards for Reporting Enzymology Data (1,251 words) [view diff] exact match in snippet view article find links to article

(18 October 2010). "A large-scale protein-function database". Nature Chemical Biology. 6 (11): 785. doi:10.1038/nchembio.460. PMC 3245624. PMID 20956966

Propofol (5,679 words) [view diff] exact match in snippet view article find links to article

site on mammalian GABAA receptors identified by photolabeling". Nature Chemical Biology. 9 (11): 715–720. doi:10.1038/nchembio.1340. PMC 3951778. PMID 24056400

CU-CPT9a (345 words) [view diff] exact match in snippet view article find links to article

inhibition of TLR8 through stabilization of its resting state". Nature Chemical Biology. 14 (1): 58–64. doi:10.1038/nchembio.2518. PMC 5726935. PMID 29155428

Two-state trajectory (1,664 words) [view diff] exact match in snippet view article find links to article

single enzyme molecules: Michaelis-Menten equation revisited". Nature Chemical Biology. 2 (2): 87–94. doi:10.1038/nchembio759. PMID 16415859. S2CID 2201882

Calicheamicin (1,505 words) [view diff] exact match in snippet view article find links to article

drive the equilibria of glycosyltransferase-catalyzed reactions". Nature Chemical Biology. 7 (10): 685–91. doi:10.1038/nchembio.638. PMC 3177962. PMID 21857660

Martin Högbom (474 words) [view diff] exact match in snippet view article find links to article

"Scavenging of superoxide by a membrane-bound superoxide oxidase". Nature Chemical Biology. 14 (8): 788–793. doi:10.1038/s41589-018-0072-x. ISSN 1552-4469

Non-proteinogenic amino acids (2,864 words) [view diff] exact match in snippet view article find links to article

S.; Söll, D. (2007). "Natural expansion of the genetic code". Nature Chemical Biology. 3 (1): 29–35. doi:10.1038/nchembio847. PMID 17173027. Avan, Ilker;

BI 99179 (608 words) [view diff] exact match in snippet view article find links to article

synthase inhibitor binds β-ketoacyl reductase in the keto-substrate site". Nature Chemical Biology. 10 (9): 774. doi:10.1038/nchembio.1603. PMID 25086508.

Hans Knöll (1,419 words) [view diff] exact match in snippet view article find links to article

C (Jul 2007). "Natural products at the Hans Knöll Institute". Nature Chemical Biology. 3 (7): 367. doi:10.1038/nchembio0707-367. PMID 17576418. Hans

PITPNM3 (1,094 words) [view diff] exact match in snippet view article find links to article

transfer proteins and cellular nanoreactors for lipid signaling". Nature Chemical Biology. 2 (11): 576–583. doi:10.1038/nchembio835. ISSN 1552-4450. PMID 17051233

Stephen J. Lippard (3,848 words) [view diff] exact match in snippet view article find links to article

Stephen J. (October 2006). "The inorganic side of chemical biology". Nature Chemical Biology. 2 (10): 504–507. doi:10.1038/nchembio1006-504. PMID 16983380.

Proteinogenic amino acid (1,633 words) [view diff] exact match in snippet view article find links to article

Söll D (January 2007). "Natural expansion of the genetic code". Nature Chemical Biology. 3 (1): 29–35. doi:10.1038/nchembio847. PMID 17173027. Lobanov

Fic/DOC protein family (837 words) [view diff] exact match in snippet view article find links to article

an inverted substrate to phosphorylate and inactivate EF-Tu". Nature Chemical Biology. 9 (12): 811–7. doi:10.1038/nchembio.1364. PMC 3836179. PMID 24141193

PAC-1 (1,787 words) [view diff] exact match in snippet view article find links to article

procaspase-3 to caspase-3 as a personalized anticancer strategy". Nature Chemical Biology. 2 (10): 543–550. doi:10.1038/nchembio814. PMID 16936720. S2CID 1689173

Cliotide (564 words) [view diff] exact match in snippet view article find links to article

Asx-specific ligase enabling peptide macrocyclization and synthesis". Nature Chemical Biology. 10 (9): 732–738. doi:10.1038/nchembio.1586. hdl:10220/38787. PMID 25038786

Ferritin (5,289 words) [view diff] exact match in snippet view article find links to article

ferritin regulates iron storage via Fe(II)-Fe(III) displacement". Nature Chemical Biology. 8 (11): 941–948. doi:10.1038/nchembio.1071. PMID 23001032. Watt

PI4KB (1,334 words) [view diff] exact match in snippet view article find links to article

2010). "Translation of the phosphoinositide code by PI effectors". Nature Chemical Biology. 6 (7): 507–13. doi:10.1038/nchembio.390. PMC 3182472. PMID 20559318

Doxorubicin (4,506 words) [view diff] exact match in snippet view article find links to article

the genome with anti-cancer drugs defines target specificities". Nature Chemical Biology. 11 (7): 472–480. doi:10.1038/nchembio.1811. PMID 25961671. Weiss

Michael Z. Lin (923 words) [view diff] exact match in snippet view article find links to article

drug control of protein production via a self-excising degron". Nature Chemical Biology. 11 (9): 713–20. doi:10.1038/nchembio.1869. PMC 4543534. PMID 26214256

Water quality (5,880 words) [view diff] exact match in snippet view article find links to article

"Programming cell-free biosensors with DNA strand displacement circuits". Nature Chemical Biology. 18 (4): 385–393. doi:10.1038/s41589-021-00962-9. ISSN 1552-4469

KDM1A (2,110 words) [view diff] exact match in snippet view article find links to article

"CRISPR-suppressor scanning reveals a nonenzymatic role of LSD1 in AML". Nature Chemical Biology. 15 (5): 529–539. doi:10.1038/s41589-019-0263-0. PMC 7679026. PMID 30992567

Water quality (5,880 words) [view diff] exact match in snippet view article find links to article

"Programming cell-free biosensors with DNA strand displacement circuits". Nature Chemical Biology. 18 (4): 385–393. doi:10.1038/s41589-021-00962-9. ISSN 1552-4469

Cellular differentiation (6,030 words) [view diff] exact match in snippet view article find links to article

"Metabolic oxidation regulates embryonic stem cell differentiation". Nature Chemical Biology. 6 (6): 411–417. doi:10.1038/nchembio.364. ISSN 1552-4469. PMC 2873061

Network medicine (2,604 words) [view diff] exact match in snippet view article find links to article

(2008). Network pharmacology: the next paradigm in drug discovery. Nature Chemical Biology, 4(11), 682–690. Roeland van Wijk et al., Non-monotonic dynamics

Fluorescence recovery after photobleaching (2,725 words) [view diff] exact match in snippet view article find links to article

"Inactive-state preassembly of Gq-coupled receptors and Gq heterotrimers". Nature Chemical Biology. 7 (11): 740–747. doi:10.1038/nchembio.642. PMC 3177959. PMID 21873996

Degron (1,521 words) [view diff] exact match in snippet view article find links to article

Matouschek, Andreas (2009-11-01). "Targeting proteins for degradation". Nature Chemical Biology. 5 (11): 815–822. doi:10.1038/nchembio.250. ISSN 1552-4450. PMC 4228941

Toxin-antitoxin system (5,971 words) [view diff] exact match in snippet view article find links to article

"Toxin-antitoxin systems in bacterial growth arrest and persistence". Nature Chemical Biology. 12 (4): 208–14. doi:10.1038/nchembio.2044. PMID 26991085. Mine

HDAC7 (2,058 words) [view diff] exact match in snippet view article find links to article

deacetylase inhibition via a nonchelating zinc-binding group". Nature Chemical Biology. 9 (5): 319–325. doi:10.1038/nchembio.1223. ISSN 1552-4450. PMID 23524983

NED-19 (438 words) [view diff] exact match in snippet view article find links to article

"Identification of a chemical probe for NAADP by virtual screening". Nature Chemical Biology. 5 (4): 220–6. doi:10.1038/nchembio.150. PMC 2659327. PMID 19234453

Targeted covalent inhibitors (2,061 words) [view diff] exact match in snippet view article find links to article

inhibition of a protease by targeting a noncatalytic cysteine". Nature Chemical Biology. 7 (1): 22–24. doi:10.1038/nchembio.492. PMID 21113170. Ostrem

Small activating RNA (1,110 words) [view diff] exact match in snippet view article find links to article

expression in mammalian cells with promoter-targeted duplex RNAs". Nature Chemical Biology. 3 (3): 166–173. doi:10.1038/nchembio860. ISSN 1552-4450. PMID 17259978

UCK2 (2,778 words) [view diff] exact match in snippet view article find links to article

CRISPR-Cas9 screens enable antiviral drug target identification". Nature Chemical Biology. 12 (5): 361–6. doi:10.1038/nchembio.2050. PMC 4836973. PMID 27018887

Proteolysis targeting chimera (1,645 words) [view diff] exact match in snippet view article find links to article

"Catalytic in vivo protein knockdown by small-molecule PROTACs". Nature Chemical Biology. 11 (8): 611–617. doi:10.1038/nchembio.1858. PMC 4629852. PMID 26075522

Cholera autoinducer-1 (1,823 words) [view diff] exact match in snippet view article find links to article

autoinducer CAI-1: analysis of the biosynthetic enzyme CqsA". Nature Chemical Biology. 5 (12): 891–895. doi:10.1038/nchembio.237. ISSN 1552-4450. PMC 2847429

Phenylketonuria (6,151 words) [view diff] exact match in snippet view article find links to article

into toxic fibrils suggests amyloid etiology in phenylketonuria". Nature Chemical Biology. 8 (8): 701–6. doi:10.1038/nchembio.1002. PMID 22706200. Surtees

CA77.1 (284 words) [view diff] exact match in snippet view article find links to article

of chaperone-mediated autophagy by retinoic acid derivatives". Nature Chemical Biology. 9 (6): 374–82. doi:10.1038/nchembio.1230. PMC 3661710. PMID 23584676

PI4K2A (1,482 words) [view diff] exact match in snippet view article find links to article

2010). "Translation of the phosphoinositide code by PI effectors". Nature Chemical Biology. 6 (7): 507–513. doi:10.1038/nchembio.390. PMC 3182472. PMID 20559318

SWI/SNF (3,947 words) [view diff] exact match in snippet view article find links to article

vulnerabilities in cancer demonstrated via structure-based PROTAC design". Nature Chemical Biology. 15 (7): 672–680. doi:10.1038/s41589-019-0294-6. ISSN 1552-4469

Fluorinase (1,029 words) [view diff] exact match in snippet view article find links to article

characterization of a marine bacterial SAM-dependent chlorinase". Nature Chemical Biology. 4 (1): 69–74. doi:10.1038/nchembio.2007.56. PMC 2762381. PMID 18059261

Chimeric small molecule therapeutics (2,120 words) [view diff] exact match in snippet view article find links to article

hydrophobic tagging-induced degradation of HaloTag fusion proteins". Nature Chemical Biology. 7 (8): 538–543. doi:10.1038/nchembio.597. PMC 3139752. PMID 21725302

Cyclotide (2,507 words) [view diff] exact match in snippet view article find links to article

ligase enabling peptide macrocyclization and synthesis" (PDF). Nature Chemical Biology. 10 (9): 732–8. doi:10.1038/nchembio.1586. hdl:10220/38787. PMID 25038786

Carotenoid oxygenase (642 words) [view diff] exact match in snippet view article find links to article

mechanism of a retinoid isomerase essential for vertebrate vision". Nature Chemical Biology. 11 (6): 409–15. doi:10.1038/nchembio.1799. PMC 4433804. PMID 25894083

Protein O-GlcNAc transferase (2,761 words) [view diff] exact match in snippet view article find links to article

pathway yields a glycosyltransferase inhibitor within cells". Nature Chemical Biology. 7 (3): 174–81. doi:10.1038/nchembio.520. PMC 3202988. PMID 21258330

Crossover junction endodeoxyribonuclease (1,215 words) [view diff] exact match in snippet view article find links to article

enzymes use multivalency to keep the Holliday junction dynamic". Nature Chemical Biology. 15 (3): 269–275. doi:10.1038/s41589-018-0209-y. PMC 6377835. PMID 30664685

Ludger Johannes (1,920 words) [view diff] exact match in snippet view article find links to article

inhibitor Retro-2. Nat Chem Biol 16: 327–336. Comments: Hesso Farhan, Nature Chemical Biology volume 16, pages 229–230 (2020) Watkins EB, Majewski J, Chi EY

Metalloprotein (5,335 words) [view diff] exact match in snippet view article find links to article

self-cleaving ribozymes revealed by comparative genomics analysis". Nature Chemical Biology. 11 (8): 606–10. doi:10.1038/nchembio.1846. PMC 4509812. PMID 26167874

Signal transduction (7,609 words) [view diff] exact match in snippet view article find links to article

preassembly of G(q)-coupled receptors and G(q) heterotrimers". Nature Chemical Biology. 7 (10): 740–7. doi:10.1038/nchembio.642. PMC 3177959. PMID 21873996

Nitrogenase (5,048 words) [view diff] exact match in snippet view article find links to article

structure of vanadium nitrogenase reveals an unusual bridging ligand". Nature Chemical Biology. 13 (9): 956–960. doi:10.1038/nchembio.2428. PMC 5563456. PMID 28692069

Consortium for Functional Glycomics (1,768 words) [view diff] exact match in snippet view article find links to article

Collins BE (May 2006). "Sweet spots in functional glycomics". Nature Chemical Biology. 2 (5): 238–48. doi:10.1038/nchembio785. PMID 16619023. S2CID 22207047

PTPN22 (3,897 words) [view diff] exact match in snippet view article find links to article

2012). "LYP inhibits T-cell activation when dissociated from CSK". Nature Chemical Biology. 8 (5): 437–446. doi:10.1038/nchembio.916. PMC 3329573. PMID 22426112

MALT1 (2,753 words) [view diff] exact match in snippet view article find links to article

molecular corrector rescuing function in an immunodeficient patient". Nature Chemical Biology. 15 (3): 304–313. doi:10.1038/s41589-018-0222-1. PMID 30692685

Fungal isolate (966 words) [view diff] exact match in snippet view article find links to article

"Identification of the toxic trigger in mushroom poisoning". Nature Chemical Biology. 5 (7): 465–7. doi:10.1038/nchembio.179. PMID 19465932. Kuhr, I;

Low-density lipoprotein receptor-related protein 8 (3,439 words) [view diff] exact match in snippet view article find links to article

selenoprotein translation exposes a ferroptosis vulnerability". Nature Chemical Biology. 18 (7): 751–761. doi:10.1038/s41589-022-01033-3. ISSN 1552-4469

Xenopus (5,807 words) [view diff] exact match in snippet view article find links to article

screen reveals an inhibitor of the Mre11-Rad50-Nbs1 complex". Nature Chemical Biology. 4 (2): 119–25. doi:10.1038/nchembio.63. PMC 3065498. PMID 18176557

Biology (13,826 words) [view diff] exact match in snippet view article find links to article

"Metabolic oxidation regulates embryonic stem cell differentiation". Nature Chemical Biology. 6 (6): 411–417. doi:10.1038/nchembio.364. PMC 2873061. PMID 20436487

ERN1 (2,089 words) [view diff] exact match in snippet view article find links to article

control of the IRE1α endoribonuclease using kinase inhibitors". Nature Chemical Biology. 8 (12): 982–989. doi:10.1038/nchembio.1094. PMC 3508346. PMID 23086298

Tafazzin (6,767 words) [view diff] exact match in snippet view article find links to article

PMID 25941633. Gawrisch K (October 2012). "Tafazzin senses curvature". Nature Chemical Biology. 8 (10): 811–2. doi:10.1038/nchembio.1068. PMC 3478944. PMID 22987008

G. Marius Clore (2,735 words) [view diff] exact match in snippet view article find links to article

"Slip sliding away: new insights into DNA-protein recognition". Nature Chemical Biology. 2 (7): 353–354. doi:10.1038/nchembio0706-353. PMID 16783338. S2CID 12357797

SAFit2 (523 words) [view diff] exact match in snippet view article find links to article

"Selective inhibitors of the FK506-binding protein 51 by induced fit". Nature Chemical Biology. 11 (1): 33–7. doi:10.1038/nchembio.1699. PMID 25436518. Balsevich

Archaeol (2,082 words) [view diff] exact match in snippet view article find links to article

multifunctional enzyme is involved in bacterial ether lipid biosynthesis". Nature Chemical Biology. 10 (6): 425–427. doi:10.1038/nchembio.1526. ISSN 1552-4450. PMID 24814673

Programmed cell death (6,801 words) [view diff] exact match in snippet view article find links to article

cell death with therapeutic potential for ischemic brain injury". Nature Chemical Biology. 1 (2): 112–119. doi:10.1038/nchembio711. ISSN 1552-4450. PMID 16408008

Nanobiotechnology (5,219 words) [view diff] exact match in snippet view article find links to article

"Programming cell-free biosensors with DNA strand displacement circuits". Nature Chemical Biology. 18 (4): 385–393. doi:10.1038/s41589-021-00962-9. ISSN 1552-4469

Amyloid (6,536 words) [view diff] exact match in snippet view article find links to article

"Amyloid formation by globular proteins under native conditions". Nature Chemical Biology. 5 (1): 15–22. doi:10.1038/nchembio.131. PMID 19088715. Michaels

Marc Baldus (1,227 words) [view diff] exact match in snippet view article find links to article

PMID 12960362. Baldus, Marc (2018). "GPCR: Lock and key become flexible". Nature Chemical Biology. 14 (3): 201–202. doi:10.1038/nchembio.2567. PMID 29443979. Lange

Oxycodone (11,539 words) [view diff] exact match in snippet view article find links to article

biomanufacturing platform for natural and semisynthetic opioids". Nature Chemical Biology. 10 (10). Nature Portfolio: 837–844. doi:10.1038/nchembio.1613

Thalidomide (7,474 words) [view diff] exact match in snippet view article find links to article

a cereblon substrate involved in thalidomide teratogenicity". Nature Chemical Biology. 15 (11): 1077–1084. doi:10.1038/s41589-019-0366-7. PMID 31591562

Protein–protein interaction (8,383 words) [view diff] exact match in snippet view article find links to article

preassembly of G(q)-coupled receptors and G(q) heterotrimers". Nature Chemical Biology. 7 (10): 740–747. doi:10.1038/nchembio.642. PMC 3177959. PMID 21873996

5-Formylcytosine (917 words) [view diff] exact match in snippet view article find links to article

"5-Formylcytosine can be a stable DNA modification in mammals". Nature Chemical Biology. 11 (8): 555–557. doi:10.1038/nchembio.1848. ISSN 1552-4469. PMC 5486442

Artificial intelligence (28,247 words) [view diff] exact match in snippet view article find links to article

α-synuclein aggregation using structure-based iterative learning". Nature Chemical Biology. 20 (5). Nature: 634–645. doi:10.1038/s41589-024-01580-x. PMC 11062903

GABAA receptor (5,962 words) [view diff] exact match in snippet view article find links to article

receptor models identify new benzodiazepine binding-site ligands". Nature Chemical Biology. 8 (5): 455–464. doi:10.1038/nchembio.917. PMC 3368153. PMID 22446838

Bioorthogonal chemistry (5,098 words) [view diff] exact match in snippet view article find links to article

A; Bertozzi, Carolyn R (2005). "Chemistry in living systems". Nature Chemical Biology. 1 (1): 13–21. doi:10.1038/nchembio0605-13. PMID 16407987. S2CID 40548615

Peptide loading complex (1,550 words) [view diff] exact match in snippet view article find links to article

MHC-I by TAPBPR is driven by a negative allostery release cycle". Nature Chemical Biology. 14 (8): 811–820. doi:10.1038/s41589-018-0096-2. PMC 6202177. PMID 29988068

Janelle Ayres (1,383 words) [view diff] exact match in snippet view article find links to article

branched-chain fatty acid synthesis in adipose tissues. (2018) Nature Chemical Biology. 14(11):1021-1031. DOI: 10.1038/s41589-018-0132-2 Sanchez, K.K

William Bachovchin (1,320 words) [view diff] exact match in snippet view article find links to article

induces pro-caspase-1-dependent monocyte and macrophage pyroptosis". Nature Chemical Biology. 13 (1): 46–53. doi:10.1038/nchembio.2229. PMC 5477230. PMID 27820798

Fatty acid synthase (4,023 words) [view diff] exact match in snippet view article find links to article

inhibitor binds β-ketoacyl reductase in the keto-substrate site". Nature Chemical Biology. 10 (9): 774–779. doi:10.1038/nchembio.1603. PMID 25086508. Vander

Prion (11,030 words) [view diff] exact match in snippet view article find links to article

(May 2023). "A structural basis for prion strain diversity". Nature Chemical Biology. 19 (5): 607–613. doi:10.1038/s41589-022-01229-7. PMC 10154210

Reactive oxygen species (8,459 words) [view diff] exact match in snippet view article find links to article

of reactive oxygen species in signaling or stress responses". Nature Chemical Biology. 7 (8): 504–511. doi:10.1038/nchembio.607. PMC 3390228. PMID 21769097

RPE65 (2,829 words) [view diff] exact match in snippet view article find links to article

mechanism of a retinoid isomerase essential for vertebrate vision". Nature Chemical Biology. 11 (6): 409–15. doi:10.1038/nchembio.1799. PMC 4433804. PMID 25894083

JAK-STAT signaling pathway (6,845 words) [view diff] exact match in snippet view article find links to article

role for JAK3 catalytic activity in IL-2 receptor signaling". Nature Chemical Biology. 12 (5): 373–379. doi:10.1038/nchembio.2056. PMC 4837022. PMID 27018889

Sonic hedgehog protein (7,266 words) [view diff] exact match in snippet view article find links to article

that binds Hedgehog and blocks its signaling in human cells". Nature Chemical Biology. 5 (3): 154–156. doi:10.1038/nchembio.142. PMC 2770933. PMID 19151731

PIN1 (2,792 words) [view diff] exact match in snippet view article find links to article

2007). "Prolyl cis-trans isomerization as a molecular timer". Nature Chemical Biology. 3 (10): 619–29. doi:10.1038/nchembio.2007.35. PMID 17876319. da

Kinetic exclusion assay (2,009 words) [view diff] exact match in snippet view article find links to article

'decoy receptor' effectively silences the Gas6/Axl signaling axis". Nature Chemical Biology. 10 (11): 977–983. doi:10.1038/nchembio.1636. ISSN 1552-4450. PMC 4372605

Antioxidant (10,681 words) [view diff] exact match in snippet view article find links to article

2009). "Bacillithiol is an antioxidant thiol produced in Bacilli". Nature Chemical Biology. 5 (9): 625–627. doi:10.1038/nchembio.189. PMC 3510479. PMID 19578333

TMP-HTag (446 words) [view diff] exact match in snippet view article find links to article

(October 2017). "Optogenetic control of kinetochore function". Nature Chemical Biology. 13 (10): 1096–1101. doi:10.1038/nchembio.2456. ISSN 1552-4469

Dirty drug (931 words) [view diff] exact match in snippet view article find links to article

"Network pharmacology: The next paradigm in drug discovery". Nature Chemical Biology. 4 (11): 682–90. doi:10.1038/nchembio.118. PMID 18936753. Factor

Calprotectin (2,176 words) [view diff] exact match in snippet view article find links to article

"Human calprotectin is an iron-sequestering host-defense protein". Nature Chemical Biology. 11 (10): 765–71. doi:10.1038/nchembio.1891. PMC 4575267. PMID 26302479

Jelly roll fold (2,890 words) [view diff] exact match in snippet view article find links to article

dioxygenases: cellular sensors and regulators jelly rolled into one?". Nature Chemical Biology. 3 (3): 144–53. doi:10.1038/nchembio863. PMID 17301803. Aik W,

Circular permutation in proteins (3,511 words) [view diff] exact match in snippet view article find links to article

"Directed evolution drives the next generation of biocatalysts". Nature Chemical Biology. 5 (8): 567–73. doi:10.1038/nchembio.203. PMID 19620998. Weiner

DNA (17,848 words) [view diff] exact match in snippet view article find links to article

(October 2009). "DNA-catalyzed sequence-specific hydrolysis of DNA". Nature Chemical Biology. 5 (10): 718–20. doi:10.1038/nchembio.201. PMC 2746877. PMID 19684594

Enzyme kinetics (9,537 words) [view diff] exact match in snippet view article find links to article

single enzyme molecules: Michaelis-Menten equation revisited". Nature Chemical Biology. 2 (2): 87–94. doi:10.1038/nchembio759. PMID 16415859. S2CID 2201882

Robustness (evolution) (4,629 words) [view diff] exact match in snippet view article

Karplus, M (Jun 17, 2011). "Behind the folding funnel diagram". Nature Chemical Biology. 7 (7): 401–4. doi:10.1038/nchembio.565. PMID 21685880. Tokuriki

G protein-coupled receptor (9,380 words) [view diff] exact match in snippet view article find links to article

preassembly of G(q)-coupled receptors and G(q) heterotrimers". Nature Chemical Biology. 7 (10): 740–7. doi:10.1038/nchembio.642. PMC 3177959. PMID 21873996

Wolfgang Lubitz (1,986 words) [view diff] exact match in snippet view article find links to article

[FeFe]-hydrogenases by an inorganic [2Fe] active site mimic". Nature Chemical Biology. 9 (10): 607–609. doi:10.1038/nchembio.1311. ISSN 1552-4450. PMC 3795299

Stapled peptide (1,723 words) [view diff] exact match in snippet view article find links to article

helix is an exclusive MCL-1 inhibitor and apoptosis sensitizer". Nature Chemical Biology. 6 (8): 595–601. doi:10.1038/nchembio.391. ISSN 1552-4469. PMC 3033224

Nucleic acid analogue (5,299 words) [view diff] exact match in snippet view article find links to article

(August 2005). "A network of orthogonal ribosome x mRNA pairs". Nature Chemical Biology. 1 (3): 159–66. doi:10.1038/nchembio719. PMID 16408021. S2CID 37181098

Floral scent (3,145 words) [view diff] exact match in snippet view article find links to article

"The function of terpene natural products in the natural world". Nature Chemical Biology. 3 (7): 408–414. doi:10.1038/nchembio.2007.5. PMID 17576428. Harmer

2022 in the environment (1,844 words) [view diff] exact match in snippet view article find links to article

"Programming cell-free biosensors with DNA strand displacement circuits". Nature Chemical Biology. 18 (4): 385–393. doi:10.1038/s41589-021-00962-9. ISSN 1552-4469

Alessio Ciulli (1,087 words) [view diff] exact match in snippet view article find links to article

PROTAC cooperative recognition for selective protein degradation". Nature Chemical Biology. 13 (5): 514–521. doi:10.1038/nchembio.2329. PMC 5392356. PMID 28288108

Cannabis (drug) (17,610 words) [view diff] exact match in snippet view article

glycine receptors contributes to cannabis-induced analgesia". Nature Chemical Biology. 7 (5): 296–303. doi:10.1038/nchembio.552. PMC 3388539. PMID 21460829

Strigolactone (3,570 words) [view diff] exact match in snippet view article find links to article

receptor and butenolide complex mediates strigolactone perception". Nature Chemical Biology. 12 (10): 787–794. doi:10.1038/nchembio.2147. PMC 5030144. PMID 27479744

Protein O-GlcNAcase (2,189 words) [view diff] exact match in snippet view article find links to article

2017). "Structural and functional insight into human O-GlcNAcase". Nature Chemical Biology. 13 (6): 610–612. doi:10.1038/nchembio.2358. PMC 5438047. PMID 28346405

PPAP2B (2,069 words) [view diff] exact match in snippet view article find links to article

(July 2010). "Seeing the future of bioactive lipid drug targets". Nature Chemical Biology. 6 (7): 476–9. doi:10.1038/nchembio.394. PMID 20559310. Schober

Elizabeth M. Boon (557 words) [view diff] exact match in snippet view article find links to article

molecular basis for NO selectivity in soluble guanylate cyclase". Nature Chemical Biology. 1 (1): 53–59. doi:10.1038/nchembio704. ISSN 1552-4469. PMID 16407994

Ivano Bertini (525 words) [view diff] exact match in snippet view article find links to article

ChemViews Banci, L.; Luchinat, C. (2012). "Ivano Bertini 1940-2012". Nature Chemical Biology. 8 (10): 807. doi:10.1038/nchembio.1072. PMID 22986998. S2CID 22004688

Russulaceae (7,504 words) [view diff] exact match in snippet view article find links to article

"Identification of the toxic trigger in mushroom poisoning". Nature Chemical Biology. 5 (7): 465–7. doi:10.1038/nchembio.179. PMID 19465932. Yaltirak

Center for Cell and Gene Therapy (552 words) [view diff] exact match in snippet view article find links to article

directs differentiation of human ESCs into the pancreatic lineage". Nature Chemical Biology. 5 (4): 258–265. doi:10.1038/nchembio.154. PMID 19287398. Deneen

Undecaprenyl phosphate N,N'-diacetylbacillosamine 1-phosphate transferase (1,928 words) [view diff] exact match in snippet view article find links to article

of monotopic phosphoglycosyl transferase underpins function". Nature Chemical Biology. 14 (6): 538–541. doi:10.1038/s41589-018-0054-z. PMC 6202225. PMID 29769739

Matthew Fuchter (1,500 words) [view diff] exact match in snippet view article find links to article

a nonspecific inhibitor of histone lysine methyltransferases". Nature Chemical Biology. 9 (3): 136–137. doi:10.1038/nchembio.1187. ISSN 1552-4450. PMID 23416387

Halovir (1,885 words) [view diff] exact match in snippet view article find links to article

polyketide-nonribosomal peptide in nematodes that promotes larval survival". Nature Chemical Biology. 12 (10): 770–772. doi:10.1038/nchembio.2144. ISSN 1552-4469. PMC 5030153

RoGFP (1,214 words) [view diff] exact match in snippet view article find links to article

monitoring of basal H2O2 levels with peroxiredoxin-based probes". Nature Chemical Biology. 12 (6): 437–43. doi:10.1038/nchembio.2067. PMID 27089028.

Fungus-growing ants (6,719 words) [view diff] exact match in snippet view article find links to article

"Dentigerumycin: a bacterial mediator of an ant-fungus symbiosis". Nature Chemical Biology. 5 (6): 391–393. doi:10.1038/nchembio.159. ISSN 1552-4469. PMC 2748230

Ferroptosis (6,519 words) [view diff] exact match in snippet view article find links to article

of cancer cell sensitivity to canonical ferroptosis inducers". Nature Chemical Biology. 16 (12): 1351–1360. doi:10.1038/s41589-020-0613-y. PMC 8299533

Gram domain containing 1b (1,452 words) [view diff] exact match in snippet view article find links to article

antibody-based tools for studying tryptophan C-mannosylation". Nature Chemical Biology. 17 (4): 428–437. doi:10.1038/s41589-020-00727-w. PMID 33542533

Angiotensin-converting enzyme 2 (5,225 words) [view diff] exact match in snippet view article find links to article

mitigates lung injury and death induced by SARS-CoV-2 variants". Nature Chemical Biology. 18 (3): 342–351. doi:10.1038/s41589-021-00965-6. PMC 8885411.

Biomolecular condensate (8,679 words) [view diff] exact match in snippet view article find links to article

protein assemblies with tunable phase diagrams in living cells". Nature Chemical Biology. 16 (9): 939–945. doi:10.1038/s41589-020-0576-z. hdl:11573/1435875

Christy Landes (913 words) [view diff] exact match in snippet view article find links to article

isolated agonist-binding domains from single AMPA receptors". Nature Chemical Biology. 7 (3): 168–173. doi:10.1038/nchembio.523. PMC 3082477. PMID 21297640

Dauer larva (2,438 words) [view diff] exact match in snippet view article find links to article

molecule promotes C. elegans reproductive development and aging". Nature Chemical Biology. 15 (8): 838–845. doi:10.1038/s41589-019-0321-7. PMC 6650165. PMID 31320757

Morphinone reductase (1,534 words) [view diff] exact match in snippet view article find links to article

biomanufacturing platform for natural and semisynthetic opioids". Nature Chemical Biology. 10 (10): 837–844. doi:10.1038/nchembio.1613. ISSN 1552-4450. PMC 4167936

Aled Edwards (2,130 words) [view diff] exact match in snippet view article find links to article

J. (August 2015). "The promise and peril of chemical probes". Nature Chemical Biology. 11 (8): 536–541. doi:10.1038/nchembio.1867. ISSN 1552-4469. PMC 4706458

Tandem mass spectrometry (7,443 words) [view diff] exact match in snippet view article find links to article

2005). "Mass spectrometry-based proteomics turns quantitative". Nature Chemical Biology. 1 (5): 252–62. doi:10.1038/nchembio736. PMID 16408053. S2CID 32054251

Epigenetics (18,274 words) [view diff] exact match in snippet view article find links to article

nuclear RNA is a major substrate of the obesity-associated FTO". Nature Chemical Biology. 7 (12): 885–7. doi:10.1038/nchembio.687. PMC 3218240. PMID 22002720

Gamma-butyrobetaine dioxygenase (2,772 words) [view diff] exact match in snippet view article find links to article

2008). "Expanding chemical biology of 2-oxoglutarate oxygenases". Nature Chemical Biology. 4 (3): 152–6. doi:10.1038/nchembio0308-152. PMID 18277970. Sesti

Stephen Warren (geneticist) (1,376 words) [view diff] no match in snippet view article

and behavioral phenotypes of fragile X syndrome in Drosophila. Nature Chemical-Biology 4:256-263 (2008). Davies, KE and Warren, ST (Editors): Genome Analysis

Geosmin synthase (1,519 words) [view diff] exact match in snippet view article find links to article

odorant geosmin by a bifunctional Streptomyces coelicolor enzyme". Nature Chemical Biology. 3 (11): 711–5. doi:10.1038/nchembio.2007.29. PMC 3013058. PMID 17873868

Abaucin (500 words) [view diff] exact match in snippet view article find links to article

discovery of an antibiotic targeting Acinetobacter baumannii". Nature Chemical Biology. 19 (11): 1342–1350. doi:10.1038/s41589-023-01349-8. PMID 37231267

Nucleic acid structure determination (4,459 words) [view diff] exact match in snippet view article find links to article

challenges for chemical probing of RNA structure inside living cells". Nature Chemical Biology. 11 (12): 933–941. doi:10.1038/nchembio.1958. PMC 5068366. PMID 26575240

Pentabromopseudilin (1,380 words) [view diff] exact match in snippet view article find links to article

polybrominated aromatic organic compounds by marine bacteria". Nature Chemical Biology. 10 (8): 640–647. doi:10.1038/NCHEMBIO.1564. PMC 4104138. PMID 24974229

Reduced dimensions form (2,750 words) [view diff] exact match in snippet view article find links to article

single enzyme molecules: Michaelis-Menten equation revisited". Nature Chemical Biology. 2 (2). Springer Science and Business Media LLC: 87–94. doi:10

Natural product (12,428 words) [view diff] exact match in snippet view article find links to article

even if it can be prepared by total synthesis. "All natural". Nature Chemical Biology. 3 (7): 351. July 2007. doi:10.1038/nchembio0707-351. PMID 17576412

Chemical ecology (6,025 words) [view diff] exact match in snippet view article find links to article

biomineralization by a metallophore from a gold-associated microbe". Nature Chemical Biology. 9 (4): 241–243. doi:10.1038/nchembio.1179. ISSN 1552-4450. Fraenkel

Metabolic network modelling (5,355 words) [view diff] exact match in snippet view article find links to article

(February 2013). "Metabolite damage and its repair or pre-emption". Nature Chemical Biology. 9 (2): 72–80. doi:10.1038/nchembio.1141. PMID 23334546. Hanson

RNA editing (7,435 words) [view diff] exact match in snippet view article find links to article

reveals dynamic pseudouridylation of the mammalian transcriptome". Nature Chemical Biology. 11 (8): 592–597. doi:10.1038/nchembio.1836. PMID 26075521. Khoddami

Proteasome (12,670 words) [view diff] exact match in snippet view article find links to article

"Defining the geometry of the two-component proteasome degron". Nature Chemical Biology. 7 (3): 161–7. doi:10.1038/nchembio.521. PMC 3129032. PMID 21278740

Project 523 (2,879 words) [view diff] exact match in snippet view article find links to article

other febrifugine derivatives inhibit prolyl-tRNA synthetase". Nature Chemical Biology. 8 (3): 311–317. doi:10.1038/nchembio.790. PMC 3281520. PMID 22327401

Dimerization of catharanthine and vindoline (1,063 words) [view diff] exact match in snippet view article find links to article

Single-cell multi-omics in the medicinal plant Catharanthus roseus. Nature Chemical Biology, 19(8), 1031–1041. https://doi.org/10.1038/s41589-023-01327-0 Encyclopædia

Albicidin (506 words) [view diff] exact match in snippet view article find links to article

albicidin consists of p-aminobenzoic acids and cyanoalanine". Nature Chemical Biology. 11 (3): 195–197. doi:10.1038/nchembio.1734. PMID 25599532. Kerwat

Folding@home (14,633 words) [view diff] exact match in snippet view article find links to article

(2010). "Protein folding: Sticky N17 speeds huntingtin pile-up". Nature Chemical Biology. 6 (1): 7–8. doi:10.1038/nchembio.279. PMID 20016493. Diwakar Shukla

EZH2 (5,393 words) [view diff] exact match in snippet view article find links to article

EZH2 blocks H3K27 methylation and kills mutant lymphoma cells". Nature Chemical Biology. 8 (11): 890–896. doi:10.1038/nchembio.1084. PMID 23023262. Qi

Chaperone-mediated autophagy (3,623 words) [view diff] exact match in snippet view article find links to article

of chaperone-mediated autophagy by retinoic acid derivatives". Nature Chemical Biology. 9 (6): 374–82. doi:10.1038/nchembio.1230. PMC 3661710. PMID 23584676

Hopanoids (4,595 words) [view diff] exact match in snippet view article find links to article

cyclases are protonases for stereoselective Brønsted acid catalysis". Nature Chemical Biology. 11 (2): 121–6. doi:10.1038/nchembio.1719. PMID 25503928. US 2017107160

Raymond J. Deshaies (2,482 words) [view diff] exact match in snippet view article find links to article

potent and specific inhibitor of proteasome isopeptidase Rpn11". Nature Chemical Biology. 13 (5): 486–493. doi:10.1038/nchembio.2326. PMC 5570473. PMID 28244987

4-Amino-5-hydroxymethyl-2-methylpyrimidine (1,452 words) [view diff] exact match in snippet view article find links to article

pyrimidine biosynthesis expands the radical SAM superfamily". Nature Chemical Biology. 4 (12): 758–65. doi:10.1038/nchembio.121. PMC 2587053. PMID 18953358

Antimicrobial resistance (22,576 words) [view diff] exact match in snippet view article find links to article

bioengineered antimicrobial lanthipeptides at nanoliter scale" (PDF). Nature Chemical Biology. 15 (5): 437–443. doi:10.1038/s41589-019-0250-5. PMID 30936500

Biosensor (12,169 words) [view diff] exact match in snippet view article find links to article

"Programming cell-free biosensors with DNA strand displacement circuits". Nature Chemical Biology. 18 (4): 385–393. doi:10.1038/s41589-021-00962-9. ISSN 1552-4469

RNA therapeutics (8,887 words) [view diff] exact match in snippet view article find links to article

G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore". Nature Chemical Biology. 10 (8): 686–91. doi:10.1038/nchembio.1561. PMC 4104137. PMID 24952597

Bump and hole (2,510 words) [view diff] exact match in snippet view article find links to article

nitric oxide via a 'bump-and-hole'-based enzyme–prodrug pair". Nature Chemical Biology. 15 (2): 151–160. doi:10.1038/s41589-018-0190-5. ISSN 1552-4450

Cholesterol signaling (1,790 words) [view diff] exact match in snippet view article find links to article

identify transbilayer asymmetry of plasma membrane cholesterol". Nature Chemical Biology. 13 (3): 268–274. doi:10.1038/nchembio.2268. PMC 5912897. PMID 28024150

Arren Bar-Even (931 words) [view diff] exact match in snippet view article find links to article

coli on formate and methanol via the reductive glycine pathway". Nature Chemical Biology. 16 (5): 538–545. doi:10.1038/s41589-020-0473-5. ISSN 1552-4469

Timeline of computing 2020–present (23,532 words) [view diff] exact match in snippet view article find links to article

discovery of an antibiotic targeting Acinetobacter baumannii". Nature Chemical Biology. 19 (11): 1342–1350. doi:10.1038/s41589-023-01349-8. ISSN 1552-4469

Pancreatic progenitor cell (2,844 words) [view diff] exact match in snippet view article find links to article

directs differentiation of human ESCs into the pancreatic lineage". Nature Chemical Biology. 5 (4): 258–265. doi:10.1038/nchembio.154. PMID 19287398. Zaret

AI-10-49 (2,849 words) [view diff] exact match in snippet view article find links to article

PMID 25678644. S2CID 20025135. Miura G (April 2015). "Free RUNX1". Nature Chemical Biology. 11 (4): 241. doi:10.1038/nchembio.1784. Pulikkan JA, Illendula

Small molecule sensors (2,557 words) [view diff] exact match in snippet view article find links to article

fluorescent sensors for studying the cell biology of metals". Nature Chemical Biology. 4 (3): 168–175. doi:10.1038/nchembio.69. PMID 18277978. Yoon,

Synthetic biology (18,749 words) [view diff] exact match in snippet view article find links to article

tetrahelical protein design for diverse oxidoreductase functions". Nature Chemical Biology. 9 (12): 826–833. doi:10.1038/nchembio.1362. PMC 4034760. PMID 24121554

Lactocillin (1,461 words) [view diff] exact match in snippet view article find links to article

to activate amide backbones during peptide cyclodehydrations". Nature Chemical Biology. 8 (6): 569–575. doi:10.1038/nchembio.944. ISSN 1552-4469. PMC 3428213

Metallo-beta-lactamase protein fold (1,060 words) [view diff] exact match in snippet view article find links to article

withstand low Zn(II) conditions by tuning metal-ligand interactions". Nature Chemical Biology. 8 (8): 698–700. doi:10.1038/nchembio.1005. PMC 3470787. PMID 22729148

Artificial cell (8,448 words) [view diff] exact match in snippet view article find links to article

cells for thermo-responsive protein synthesis and cargo release". Nature Chemical Biology: 1–7. doi:10.1038/s41589-024-01673-7. ISSN 1552-4469. PMC 11427347

Peter Karl Sorger (3,097 words) [view diff] exact match in snippet view article find links to article

potency reveal systematic variation in responses to cancer drugs". Nature Chemical Biology. 9 (11): 708–14. doi:10.1038/nchembio.1337. PMC 3947796. PMID 24013279

Optogenetics (11,930 words) [view diff] exact match in snippet view article find links to article

control of an ionotropic glutamate receptor with an optical switch". Nature Chemical Biology. 2 (1): 47–52. doi:10.1038/nchembio756. PMC 1447676. PMID 16408092

Cycloheximide chase (1,015 words) [view diff] exact match in snippet view article find links to article

eukaryotic translation elongation by cycloheximide and lactimidomycin". Nature Chemical Biology. 6 (3): 209–217. doi:10.1038/nchembio.304. PMC 2831214. PMID 20118940

Michelle Gray (2,339 words) [view diff] case mismatch in snippet view article find links to article

polyglutamine protein species in situ that best predict neurodegeneration. Nature chemical biology. 7. 925-34. 10.1038/nchembio.694. Miller, Jason & Arrasate, Montserrat

K. Christopher Garcia (2,317 words) [view diff] exact match in snippet view article find links to article

cytokine responses with engineered interleukin-4 superkines". Nature Chemical Biology. 8 (12): 990–998. doi:10.1038/nchembio.1096. ISSN 1552-4469. PMC 3508151

Timeline of biotechnology (24,501 words) [view diff] exact match in snippet view article find links to article

"Programming cell-free biosensors with DNA strand displacement circuits". Nature Chemical Biology. 18 (4): 385–393. doi:10.1038/s41589-021-00962-9. ISSN 1552-4469

Nicotinic acid adenine dinucleotide phosphate (6,140 words) [view diff] exact match in snippet view article find links to article

"Identification of a chemical probe for NAADP by virtual screening". Nature Chemical Biology. 5 (4): 220–6. doi:10.1038/nchembio.150. PMC 2659327. PMID 19234453

2-Hydroxyisobutyric acid (414 words) [view diff] exact match in snippet view article find links to article

2-Hydroxyisobutyrylation is a Widely Distributed Active Histone Mark". Nature Chemical Biology. 10 (5): 365–370. doi:10.1038/nchembio.1497. PMID 24681537. Carrola

Heat shock protein 90kDa alpha (cytosolic), member A1 (8,199 words) [view diff] exact match in snippet view article

proteomics reveal cancer-specific networks coordinated by Hsp90". Nature Chemical Biology. 7 (11): 818–26. doi:10.1038/nchembio.670. PMC 3265389. PMID 21946277

Long non-coding RNA (13,136 words) [view diff] exact match in snippet view article find links to article

Blasco MA (October 2007). "Telomere length, stem cells and aging". Nature Chemical Biology. 3 (10): 640–649. doi:10.1038/nchembio.2007.38. PMID 17876321.

Synechocystis sp. PCC 6803 (3,536 words) [view diff] exact match in snippet view article find links to article

of folding and assembly chaperones on evolvability of Rubisco". Nature Chemical Biology. 11 (2): 148–55. doi:10.1038/nchembio.1715. PMID 25558973. Oliver

POLD1 (7,954 words) [view diff] exact match in snippet view article find links to article

an iron-sulfur cluster for the formation of active complexes". Nature Chemical Biology. 8 (1): 125–32. doi:10.1038/nchembio.721. PMC 3241888. PMID 22119860

Richard I. Morimoto (4,402 words) [view diff] exact match in snippet view article find links to article

Molecule Proteostasis Regulators for Protein Conformational Disease". Nature Chemical Biology. 8 (2): 185–196. doi:10.1038/nchembio.763. PMC 3262058. PMID 22198733

Theories of general anaesthetic action (6,813 words) [view diff] exact match in snippet view article find links to article

site on mammalian GABAA receptors identified by photolabeling". Nature Chemical Biology. 9 (11): 715–720. doi:10.1038/nchembio.1340. PMC 3951778. PMID 24056400

Valosin-containing protein (5,868 words) [view diff] exact match in snippet view article find links to article

allosteric inhibitors of the ATPase VCP/p97 induce cancer cell death". Nature Chemical Biology. 9 (9): 548–56. doi:10.1038/nchembio.1313. PMID 23892893. Anderson

Rhomboid protease (4,629 words) [view diff] exact match in snippet view article find links to article

thermodynamic principles underlying intramembrane protease function". Nature Chemical Biology. 8 (9): 759–68. doi:10.1038/nchembio.1021. PMC 4028635. PMID 22797666

Swinholide (1,342 words) [view diff] exact match in snippet view article find links to article

evolutionary origin of actin-binding polyketides from diverse organisms". Nature Chemical Biology. 11 (9): 705–12. doi:10.1038/nchembio.1870. PMC 7116039. PMID 26236936

Structure validation (4,702 words) [view diff] exact match in snippet view article find links to article

Cowtan K (May 2015). "Carbohydrate anomalies in the PDB" (PDF). Nature Chemical Biology. 11 (5): 303. doi:10.1038/nchembio.1798. PMID 25885951. Lütteke

Micropeptide (3,888 words) [view diff] exact match in snippet view article find links to article

microprotein that interacts with the mRNA decapping complex". Nature Chemical Biology. 13 (2): 174–180. doi:10.1038/nchembio.2249. PMC 5247292. PMID 27918561

Transposon sequencing (1,748 words) [view diff] exact match in snippet view article find links to article

2010). "Biochemical networks: the evolution of gene annotation". Nature Chemical Biology. 6 (1): 4–5. doi:10.1038/nchembio.288. PMC 2907659. PMID 20016491

Katharina Ribbeck (2,670 words) [view diff] exact match in snippet view article find links to article

O-glycans are natural inhibitors of Candida albicans pathogenicity". Nature Chemical Biology. 18 (7): 762–773. doi:10.1038/s41589-022-01035-1. ISSN 1552-4469

Stress granule (12,562 words) [view diff] exact match in snippet view article find links to article

intrinsically disordered regions regulates phase separation". Nature Chemical Biology. 15 (1): 51–61. doi:10.1038/s41589-018-0180-7. PMID 30531905. S2CID 54471609

Gerd Ulrich Nienhaus (1,789 words) [view diff] exact match in snippet view article find links to article

reveals the energy landscape of the full-length SAM-I riboswitch". Nature Chemical Biology. 13 (11): 1172–1178. doi:10.1038/nchembio.2476. ISSN 1552-4469

Ribosomally synthesized and post-translationally modified peptides (6,238 words) [view diff] exact match in snippet view article find links to article

to activate amide backbones during peptide cyclodehydrations". Nature Chemical Biology. 8 (6): 569–75. doi:10.1038/nchembio.944. PMC 3428213. PMID 22522320

Sulfoglycolysis (2,337 words) [view diff] exact match in snippet view article find links to article

that cleaves sulfoquinovosyl diacylglyceride sulfolipids" (PDF). Nature Chemical Biology. 12 (4): 215–7. doi:10.1038/nchembio.2023. PMID 26878550. Kaur

RNA activation (3,729 words) [view diff] case mismatch in snippet view article find links to article

expression in mammalian cells with promoter-targeted duplex RNAs". Nature chemical biology. 3 (3): 166–73. doi:10.1038/nchembio860. PMID 17259978. Place,

Siderocalin (3,390 words) [view diff] exact match in snippet view article find links to article

in circulation bound to a siderocalin (Ngal)-catechol complex". Nature Chemical Biology. 6 (8): 602–9. doi:10.1038/nchembio.402. PMC 2907470. PMID 20581821

G-quadruplex (12,021 words) [view diff] exact match in snippet view article find links to article

damage identifies alternative DNA structures in human genes". Nature Chemical Biology. 8 (3): 301–310. doi:10.1038/nchembio.780. PMC 3433707. PMID 22306580

Trinucleotide repeat expansion (7,967 words) [view diff] exact match in snippet view article find links to article

therapeutics: a potential new class of pharmaceutical drugs". Nature Chemical Biology. 2 (12): 711–719. doi:10.1038/nchembio839. ISSN 1552-4469. PMC 7097247

Serotonin–norepinephrine–dopamine reuptake inhibitor (15,715 words) [view diff] exact match in snippet view article find links to article

"Network pharmacology: The next paradigm in drug discovery". Nature Chemical Biology. 4 (11): 682–90. doi:10.1038/nchembio.118. PMID 18936753. Jain

Kazushige Touhara (1,473 words) [view diff] exact match in snippet view article find links to article

aliphatic alcohol as a natural ligand for a mouse odorant receptor". Nature Chemical Biology. 9 (3): 160–162. doi:10.1038/nchembio.1164. ISSN 1552-4450. PMID 23314914

Jason Micklefield (1,701 words) [view diff] exact match in snippet view article find links to article

enzymatic assembly of peptides armed with β-lactone warheads". Nature Chemical Biology: 1–9. doi:10.1038/s41589-024-01657-7. ISSN 1552-4469. PMC 11427300

Epitranscriptomic sequencing (6,385 words) [view diff] exact match in snippet view article find links to article

identifies A-to-I RNA editing sites in the human transcriptome". Nature Chemical Biology. 6 (10): 733–740. doi:10.1038/nchembio.434. PMID 20835228. Morse

N-Acylethanolamine (19,548 words) [view diff] exact match in snippet view article find links to article

NAPE-PLD inhibitor that modulates emotional behavior in mice". Nature Chemical Biology. 16 (6): 667–675. doi:10.1038/s41589-020-0528-7. PMC 7468568. PMID 32393901

Hedgehog pathway inhibitor (3,866 words) [view diff] exact match in snippet view article find links to article

"Inhibitors of Hedgehog acyltransferase block Sonic Hedgehog signaling". Nature Chemical Biology. 9 (4): 247–249. doi:10.1038/nchembio.1184. ISSN 1552-4469. PMC 3604071

2023 in science (44,593 words) [view diff] exact match in snippet view article find links to article

discovery of an antibiotic targeting Acinetobacter baumannii". Nature Chemical Biology. 19 (11): 1342–1350. doi:10.1038/s41589-023-01349-8. ISSN 1552-4469

Fiber photometry (4,383 words) [view diff] exact match in snippet view article find links to article

"Molecular tools for imaging and recording neuronal activity". Nature Chemical Biology. 15 (2): 101–110. doi:10.1038/s41589-018-0207-0. ISSN 1552-4469

Ashutosh Chilkoti (2,711 words) [view diff] exact match in snippet view article find links to article

"Programmable synthetic biomolecular condensates for cellular control". Nature Chemical Biology. 19 (4): 518–528. doi:10.1038/s41589-022-01252-8. PMC 10786170

Stefano Pluchino (2,049 words) [view diff] exact match in snippet view article find links to article

metabolic units delivering functional Asparaginase-like protein 1". Nature Chemical Biology. 13 (9): 951–955. doi:10.1038/nchembio.2422. PMC 5563455. PMID 28671681

January–March 2022 in science (14,793 words) [view diff] exact match in snippet view article find links to article

"Programming cell-free biosensors with DNA strand displacement circuits". Nature Chemical Biology. 18 (4): 385–393. doi:10.1038/s41589-021-00962-9. ISSN 1552-4469

Poison exon (5,749 words) [view diff] exact match in snippet view article find links to article

small molecule targeting RNA for a specific splicing correction". Nature Chemical Biology. 15 (12): 1191–1198. doi:10.1038/s41589-019-0384-5. hdl:20.500