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alternate case: dNA

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central features of DNA damage, epigenetic alterations and deficient DNA repair in progression to cancer are shown in red.) DNA damage is very common

Website: English language online news coverage service. It is branded under the DNA program of Zee News. Zee5 Website: Streaming service which hosts ZMCL news

through DNA analysis began in the 1990s. Currently, there are three types of genetic origin testing, autosomal DNA (atDNA), mitochondrial DNA (mtDNA), and

known as BOLD or BOLDSystems) is a web platform specifically devoted to DNA barcoding. It is a cloud-based data storage and analysis platform developed

Human papillomavirus infection (HPV infection) is caused by a DNA virus from the Papillomaviridae family. Many HPV infections cause no symptoms and 90%

the nucleus) is preceded by the S stage of interphase (during which the DNA replication occurs) and is often followed by telophase and cytokinesis; which

records, to have 3 million paying subscribers, and to have sold 18 million DNA kits to customers. By 2022, this number had risen to 30 billion records according

nocturnal animals. In an effort to understand whether DNA repair processes can protect crustaceans against DNA damage, basic research was conducted to elucidate

their first independent album, In a World Like This. Their follow-up album DNA (2019) debuted at number one, more than two decades after the group formed

the most frequent genetic cause of developmental disabilities. In meiosis, DNA replication is followed by two rounds of cell division to produce four daughter

homology between DNA, RNA, or protein sequences, defined in terms of shared ancestry in the evolutionary history of life. Two segments of DNA can have shared

exhibit haplogroup Q (Y-DNA) mutations, but are distinct from other Indigenous Americans with various mtDNA and autosomal DNA (atDNA) mutations. This suggests

analysing descendants' DNA, however, parts of ancestral genomes are estimated by scientists. Mitochondrial DNA (mtDNA, the DNA located in mitochondria

Haplogroup E-M2, also known as E1b1a1-M2, is a human Y-chromosome DNA haplogroup. E-M2 is primarily distributed within sub-Saharan Africa. More specifically

It is a broad field utilizing numerous practices such as the analysis of DNA, fingerprints, bloodstain patterns, firearms, ballistics, and toxicology

bacterial cells in direct contact) and transduction (injection of foreign DNA by a bacteriophage virus into the host bacterium). In transformation, the

Bhutan, Ladakh, Tajikistan, Turkey, and Western China. According to ancient DNA studies, most R1a and R1b lineages would have expanded from the Caspian Sea

It is a broad field utilizing numerous practices such as the analysis of DNA, fingerprints, bloodstain patterns, firearms, ballistics, and toxicology

in chemotherapy, induces DNA lesions during meiosis that may persist in an unrepaired state as germ cells progress through DNA repair-competent phases

Bhutan, Ladakh, Tajikistan, Turkey, and Western China. According to ancient DNA studies, most R1a and R1b lineages would have expanded from the Caspian Sea

Haplogroup R1a, or haplogroup R-M420, is a human Y-chromosome DNA haplogroup which is distributed in a large region in Eurasia, extending from Scandinavia

nuclear DNA) may also cause mitochondrial DNA mutations. Most mitochondrial function and biogenesis is controlled by nuclear DNA. Human mitochondrial DNA encodes

is hemizygous, and, if both alleles are missing, it is nullizygous. The DNA sequence of a gene often varies from one individual to another. These gene

A dog breed is a particular strain of dog that was purposefully bred by humans to perform specific tasks, such as herding, hunting, and guarding. Dogs

fertilization event between two gametes. The zygote's genome is a combination of the DNA in each gamete, and contains all of the genetic information of a new individual

as reverse-transcribing viruses (with either RNA or DNA genomes) that encode an RNA-dependent DNA polymerase. RNA-dependent RNA polymerase (RdRp), also

ZyCoV-D is a DNA plasmid-based COVID-19 vaccine developed by Indian pharmaceutical company Cadila Healthcare, with support from the Biotechnology Industry

which is involved in DNA binding. The domain is composed of approximately 75 amino acid residues that collectively mediate the DNA-binding of chromatin-associated

error catastrophe, somatic mutation, accumulation of genetic material (DNA) damage (DNA damage theory of aging) and dysdifferentiation. The system theories

survival has been conclusively disproven. Scientific analysis including DNA testing confirmed that the remains are those of the imperial family, showing

realm, including certain linear single-stranded DNA (ssDNA) viruses and circular double-stranded DNA (dsDNA) viruses. These atypical members typically replicate

reduced expression of DNA repair enzymes due to epigenetic methylation of DNA repair genes or altered microRNAs that control DNA repair gene expression

In addition to the oxidative DNA damage 8-OHdG, H. pylori infection causes other characteristic DNA damages including DNA double-strand breaks. H. pylori

It is a DNA-based vaccine that encodes the SARS-CoV-2 spike protein. "Safety and Immunogenicity Study of GX-19, a COVID-19 Preventive DNA Vaccine in

several suspects were cleared through DNA evidence, alibis, or other investigative methods. In 2001, after DNA testing indicated that the East Area Rapist

DNA polymerase delta (DNA Pol δ) is an enzyme complex found in eukaryotes that is involved in DNA replication and repair. The DNA polymerase delta complex

DNA polymerase epsilon is a member of the DNA polymerase family of enzymes found in eukaryotes. It is composed of the following four subunits: POLE (central

viruses. Members of the phylum are also known as the nucleocytoplasmic large DNA viruses (NCLDV), which serves as the basis of the name of the phylum with

DNA polymerase alpha also known as Pol α is an enzyme complex found in eukaryotes that is involved in initiation of DNA replication. The DNA polymerase

evolutionary history. DNA viruses have genomes made of deoxyribonucleic acid (DNA) and are organized into two groups: double-stranded DNA (dsDNA) viruses, and

balsam poplar (P. trichocarpa) was the first tree to have its full DNA code determined by DNA sequencing, in 2006. The genus has a large genetic diversity,

mice. They bind the DNA via their winged-helix-turn-helix DNA binding motif known as the Ets domain that specifically recognizes DNA sequences that contain

human genetics, a human mitochondrial DNA haplogroup is a haplogroup defined by differences in human mitochondrial DNA. Haplogroups are used to represent

followed a previous one called AG0301-COVID‑19. "Phase I/II Study of COVID-19 DNA Vaccine (AG0302-COVID19 High-dose)". clinicaltrials.gov. United States National

The B3 DNA binding domain (DBD) is a highly conserved domain found exclusively in transcription factors (≥40 species) (Pfam PF02362) combined with other

to be a sister group to the storks of the order Ciconiiformes based on DNA–DNA hybridization and morphology. However, a 2021 analysis of mitochondrial

DNA polymerase II (also known as DNA Pol II or Pol II) is a prokaryotic DNA-dependent DNA polymerase encoded by the PolB gene. DNA Polymerase II is an

more than 20 types of DNA damage. Oxidative DNA damages cause both mutations and epigenetic alterations. RNS also cause mutagenic DNA damages. A normal cell

transcription factors. The protein contains three domains, an N-terminal DNA-binding domain, a central transcriptional activation domain and a C-terminal

of the coronavirus, Inovio announced that it had produced a preclinical DNA-based vaccine as a potential therapy for COVID-19. Inovio is in competition

to be a sister group to the storks of the order Ciconiiformes based on DNA–DNA hybridization and morphology. However, a 2021 analysis of mitochondrial

more than 20 types of DNA damage. Oxidative DNA damages cause both mutations and epigenetic alterations. RNS also cause mutagenic DNA damages. A normal cell

Mediterranean and sub-Saharan Africa. Egyptologist Barry Kemp has noted that DNA studies can only provide firm conclusions about the population of ancient

cellular and humoral immunity, and lack of interaction with the genomic DNA. While some messenger RNA vaccines, such as the Pfizer–BioNTech COVID-19

Haplogroups ~ 5% Mitochondrial DNA mtDNA represents the female lineage, Haplogroup H represent about 40% of the Norwegian mitochondrial DNA lineages H ~ 40% JT ~

cells are able to repair DNA damage in donor transforming DNA that had been UV irradiated as efficiently as they repair cellular DNA when the cells themselves

the original Guardian), Superboy (Kon-El) (a binary clone made from the DNA of Superman and Lex Luthor), and Dubbilex and his fellow DNAliens. Its 31st-century

zygote. The DNA of a cell is vulnerable to the damaging effect of oxidative free radicals produced as byproducts of cellular metabolism. DNA damage occurring

E-M215, also known as E1b1b and formerly E3b, is a major human Y-chromosome DNA haplogroup. It is a division of the macro-haplogroup E-M96, which is defined

DNA² (Japanese: D・N・A² ～何処かで失くしたあいつのアイツ～, Hepburn: Dī En Ei Tsū: Dokoka de Nakushita Aitsu no Aitsu) is a Japanese manga series written and illustrated

paternity testing of her daughter in the U.S. The court hearings included DNA testing, testimonies from various individuals claiming to be the father,

chromosomal disorder, is a missing, extra, or irregular portion of chromosomal DNA. These can occur in the form of numerical abnormalities, where there is an

contains three basic DNA-binding domains (AT-hooks) that cause the protein to bind to adenine-thymine (AT)-rich regions of nuclear DNA. HMGA2 does not directly

amalgamated with the third division DNA, to form a two-tiered league, the DNA (Divisione Nazionale A) Gold and DNA Silver. The two DNA's had separate season's, but

forkhead family of transcription factors belongs to the winged helix class of DNA-binding proteins. The protein encoded by this intronless gene contains a

been a significant area of plant research for the past 20 years. The WRKY DNA-binding domain recognizes the W-box (T)TGAC(C/T) (and variants of this sequence)

DNA Oyj (DNA Plc) is a Finnish telecommunications group that provides voice, data and TV services. In December 2020, it had over 3.5 million subscription

Duplodnaviria is a realm of viruses that includes all double-stranded DNA viruses that encode the HK97 fold major capsid protein. The HK97 fold major

structure of chromatin. CTCF binds together strands of DNA, thus forming chromatin loops, and anchors DNA to cellular structures like the nuclear lamina. It

enzymes of the non-homologous end joining (NHEJ) DNA repair pathway (DNA-PKcs, KU70, KU80, and DNA LIGASE IV) (see Figure). These enzymes repair the

fingerprints, and DNA were found in Kercher's bedroom. Guede's DNA was on the strap of Kercher's bra, which had been torn off, and his DNA was found on a

contains three basic DNA-binding domains (AT-hooks) that cause the protein to bind to adenine-thymine (AT)-rich regions of nuclear DNA. HMGA2 does not directly

Over the following weeks, particularly after misinterpreting a British DNA analysis, the Portuguese police came to believe that Madeleine had died in

Duplodnaviria is a realm of viruses that includes all double-stranded DNA viruses that encode the HK97 fold major capsid protein. The HK97 fold major

calibrated years before present, but it was not until 2013 that ancient DNA analysis techniques had improved enough to shed light on the remains. The

The Hutu (/ˈhuːtuː/), also known as the Abahutu, are a Bantu ethnic or social group which is native to the African Great Lakes region. They mainly live

viral DNA ends has been determined. Integration occurs following production of the double-stranded linear viral DNA by the viral RNA/DNA-dependent DNA polymerase

bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility

impair DNA replication machinery, either by incorporation of chemically altered nucleotides or by depleting the supply of deoxynucleotides needed for DNA replication

enzymes of the non-homologous end joining (NHEJ) DNA repair pathway (DNA-PKcs, KU70, KU80, and DNA LIGASE IV) (see Figure). These enzymes repair the

DNA sequence). This methylation results in the conversion of the cytosine to 5-methylcytosine. The formation of Me-CpG is catalyzed by the enzyme DNA

and is one of the most common viruses in humans. EBV is a double-stranded DNA virus. The virus causes infectious mononucleosis ("mono" or "glandular fever")

E-M215, also known as E1b1b and formerly E3b, is a major human Y-chromosome DNA haplogroup. It is a division of the macro-haplogroup E-M96, which is defined

structure of chromatin. CTCF binds together strands of DNA, thus forming chromatin loops, and anchors DNA to cellular structures like the nuclear lamina. It

Microviridae is a family of bacteriophages with a single-stranded DNA genome. The name of this family is derived from the ancient Greek word μικρός (mikrós)

DNA² (Japanese: D・N・A² ～何処かで失くしたあいつのアイツ～, Hepburn: Dī En Ei Tsū: Dokoka de Nakushita Aitsu no Aitsu) is a Japanese manga series written and illustrated

DNA damage-inducible transcript 3, also known as C/EBP homologous protein (CHOP), is a pro-apoptotic transcription factor that is encoded by the DDIT3

quantification of a specific DNA sequence in DNA samples. This method is used in molecular biology. Briefly, purified DNA from a biological sample (such

had their DNA results published. Each was found to belong to a different Y-DNA haplogroup: R1a, R1b, and J. R1b is also the most common Y-DNA haplogroup

roles in cellular reproduction and DNA organization, as they mediate the cleavage of single and double stranded DNA to relax supercoils, untangle catenanes

forkhead family of transcription factors belongs to the winged helix class of DNA-binding proteins. The protein encoded by this intronless gene contains a

Berberine is a quaternary ammonium salt from the protoberberine group of benzylisoquinoline alkaloids found in such plants as Berberis vulgaris (barberry)

to be released on account of DNA testing was David Vasquez, who had been convicted of homicide, in 1989. Recently, DNA evidence has been used to exonerate

cellular processes, including regulation of inducible gene transcription, DNA replication, heterochromatin organization, integration of retroviruses into

DNA primase large subunit is an enzyme that in humans is encoded by the PRIM2 gene. The replication of DNA in eukaryotic cells is carried out by a complex

DNA polymerase iota is an enzyme that in humans is encoded by the POLI gene. It is found in higher eukaryotes, and is believed to have arisen from a gene

DNA polymerase eta (Pol η), is a protein that in humans is encoded by the POLH gene. DNA polymerase eta is a eukaryotic DNA polymerase involved in the

"Mitochondrial Eve" (mt-MRCA, named for the matrilineal transmission of mtDNA), the most recent woman from whom all living humans are descended matrilineally

mitochondrial DNA into North America and Southern Africans introduced almost 15%. West Africans also introduced ~45% of Sub-Saharan African mitochondrial DNA into

are double-stranded DNA viruses. Viruses: Abalone asfarvirus African swine fever virus Dinodnavirus (Heterocapsa circularisquama DNA virus or hcDNAV) Faustovirus

OCA-B peptide bound to an Oct-1 POU domain/octamer DNA complex: specific recognition of a protein-DNA interface". Genes Dev. 13 (20): 2650–7. doi:10.1101/gad

cellular processes, including regulation of inducible gene transcription, DNA replication, heterochromatin organization, integration of retroviruses into

assigned to the damage concept, whereby the accumulation of damage (such as DNA oxidation) may cause biological systems to fail, or to the programmed ageing

quantification of a specific DNA sequence in DNA samples. This method is used in molecular biology. Briefly, purified DNA from a biological sample (such

material between generations requires timely and accurate duplication of DNA by semiconservative replication prior to cell division to ensure each daughter

was an international initiative dedicated to supporting the development of DNA barcoding as a global standard for species identification. CBOL's Secretariat

methyl transfer reactions. These types include protein methyltransferases, DNA/RNA methyltransferases, natural product methyltransferases, and non-SAM dependent

to be released on account of DNA testing was David Vasquez, who had been convicted of homicide, in 1989. Recently, DNA evidence has been used to exonerate

and Blackburn demonstrated that, during clonal aging, DNA damage increases dramatically. Thus, DNA damage in the macronucleus appears to be the cause of

Haplogroup J-M304, also known as J, is a human Y-chromosome DNA haplogroup. It is believed to have evolved in Western Asia. The clade spread from there

inaccurately reported as DNA taken only from the "underside" of a single fingernail). According to DNA Security, the fingernail DNA showed some characteristics

its discovery, its DNA-binding properties were still unknown. Neomycin has been shown to induce thermal stabilization of triplex DNA, while having little

by the FOXK2 gene. The protein encoded by this gene contains a fork head DNA binding domain. This protein can bind to the purine-rich motifs of the HIV

resulting in the formation of AP-1 (Activator Protein-1) complex which binds DNA at AP-1 specific sites at the promoter and enhancer regions of target genes

DNA Productions, Inc. was an American animation studio and production company founded in 1987 by John A. Davis and Keith Alcorn, which is best known for

Varidnaviria is a realm of viruses that includes all DNA viruses that encode major capsid proteins that contain a vertical jelly roll fold. The major

modification that is involved in many cellular processes, including cell signaling, DNA repair, gene regulation and apoptosis. Improper ADP-ribosylation has been

and MRF4. These proteins contain a conserved basic DNA binding domain that binds the E box DNA motif. They dimerize with other HLH containing proteins

Wolberger C (Feb 1999). "Structure of a HoxB1-Pbx1 heterodimer bound to DNA: role of the hexapeptide and a fourth homeodomain helix in complex formation"

the phenotype of the organism. Macronuclear DNA is derived from micronuclear DNA by amazingly extensive DNA rearrangement and amplification. The macronucleus

and MRF4. These proteins contain a conserved basic DNA binding domain that binds the E box DNA motif. They dimerize with other HLH containing proteins

OCA-B peptide bound to an Oct-1 POU domain/octamer DNA complex: specific recognition of a protein-DNA interface". Genes Dev. 13 (20): 2650–7. doi:10.1101/gad

the FOX gene family, which is characterized by a conserved 110-amino acid DNA-binding motif called the forkhead or winged helix domain. FOX genes are involved

PrimPol is a eukaryotic protein with both DNA polymerase and DNA Primase activities involved in translesion DNA synthesis. It is the first eukaryotic protein

material between generations requires timely and accurate duplication of DNA by semiconservative replication prior to cell division to ensure each daughter

development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis

nucleic acids (DNA or RNA) that occur in multiple copies throughout the genome. In many organisms, a significant fraction of the genomic DNA is repetitive

"Luka". It was later used as the basis for a remix by the British group DNA in 1990, which reached No. 1 in Austria, Germany, Greece and Switzerland

protein is a member of the RUNX family of transcription factors and has a Runt DNA-binding domain. It is essential for osteoblastic differentiation and skeletal

Television called DNA TV Limited. DNA Films has been one of the most successful production companies that is located in the United Kingdom. DNA Films is located

repair damage to their DNA, especially the repair mechanism known as homologous recombination. If the plant cannot repair DNA damage, e.g., double-strand

All of them are involved in the cell cycle regulation and synthesis of DNA in mammalian cells. E2Fs as TFs bind to the TTTCCCGC (or slight variations

identity through DNA testing. DNA tests on a lock of Anderson's hair and surviving medical samples of her tissue showed that her DNA did not match that

Geplafuvirales is an order of viruses. The following families are recognized: Geminiviridae Genomoviridae "Virus Taxonomy: 2019 Release". talk.ictvonline

Sequence homology between protein or DNA sequences is similarly defined in terms of shared ancestry. Two segments of DNA can have shared ancestry because

Wolberger C (Feb 1999). "Structure of a HoxB1-Pbx1 heterodimer bound to DNA: role of the hexapeptide and a fourth homeodomain helix in complex formation"

Y-DNA haplogroups in populations of Europe Y-DNA haplogroups in populations of the Caucasus Y-DNA haplogroups in populations of the Near East Y-DNA haplogroups

Solexa Ltd reversed into Lynx Therapeutics of Hayward. Illumina also uses the DNA colony sequencing technology, invented in 1997 by Pascal Mayer and Laurent

further suppressing DNA synthesis. pRb has the ability to reversibly inhibit DNA replication through transcriptional repression of DNA replication factors

Administration (FDA) due to its genetic health tests; as of October 2015, DNA tests ordered in the US include a revised health component, per FDA approval

activated to deal with accumulated DNA damage. In particular, single- and double-strand breaks in DNA can be repaired. The DNA damage checkpoint kinase ATM

Redondoviruses (members of the Redondoviridae) are a family of human-associated DNA viruses. Their name derives from the inferred circular structure of the viral

common Western Eurasian mtDNA haplogroups among the Buryats are H (approximately 6.8%) and U (approximately 5.4%). Another mtDNA study of Buryats shows they

recruited and activated by DNA double-strand breaks. It phosphorylates several key proteins that initiate activation of the DNA damage checkpoint, leading

an inherited mutation in the DNA repair gene BRCA1 undergo menopause prematurely, suggesting that naturally occurring DNA damages in oocytes are repaired

development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis

factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region

DNA-binding protein inhibitor ID-2 is a protein that in humans is encoded by the ID2 gene. The protein encoded by this gene belongs to the inhibitor of

Krox20) is a transcription regulatory factor, containing three zinc finger DNA-binding sites, and is highly expressed in a population of migrating neural

protein is a member of the RUNX family of transcription factors and has a Runt DNA-binding domain. It is essential for osteoblastic differentiation and skeletal

DNA tumor viruses. The E2F proteins contain several evolutionarily conserved domains found in most members of the family. These domains include a DNA

a transcription factor that is a member of the leucine zipper family of DNA-binding proteins. This protein binds to the cAMP-responsive element (CRE)

first automated DNA sequencer (1986), to identify the order of nucleotides in DNA; ink-jet oligonucleotide technology for synthesizing DNA and nanostring

with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes

bacterial process for transferring DNA from one cell to another, and is apparently an adaptation for repairing DNA damage in the recipient cell. In addition

have direct or indirect effects on the DNA: the induction of mutations, mistimed event activation, and direct DNA damage leading to mutations. The permanent

Africa Centre for Aquatic Research African Centre for DNA Barcoding: The African Centre for DNA Barcoding (ACDB) is a subsidiary of the University of

filamentous virion (i.e. body) and a linear, double-stranded DNA genome. The genome exists in A-form (A-DNA) and encodes a dimeric major capsid protein (MCP) that

tumor DNA (cfDNA) has an advantage over circulating tumor cells assays in that there is approximately 100 times more cell-free DNA than there is DNA in circulating

environmental DNA sequencing indicates that disappearance of megafaunal DNA in North America correlates in time with major changes in plant DNA, suggesting

belong in other orders, such as the Russulales and Boletales. Furthermore, DNA research has shown that many non-agarics, including some of the clavarioid

loop. The DBD of each HSF1 monomer recognizes the sequence nGAAn on target DNA. Repeated sequences of the nGAAn pentamer constitute heat shock elements

Biology in Cambridge, he developed and subsequently refined the first-ever DNA sequencing technique, which vastly expanded the number of feasible experiments

the marmoset. Recent research shows most marmosets are chimeras, sharing DNA with their fraternal twins. 95% of marmoset fraternal twins trade blood through

anaemia (FA) is a rare, AR, genetic disease resulting in impaired response to DNA damage in the FA/BRCA pathway. Although it is a very rare disorder, study

of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-YGYGGT-3' found in a number of enhancers and promoters, and can

and hepatitis B vaccine. According to immunologist Hugh McDevitt, "Cohen's DNA cloning technology has helped biologists in virtually every field". Without

In general, DNA damage appears to be the primary underlying cause of cancer. Though most DNA damages are repairable, leftover unrepaired DNA damages from

conserved domains including a highly conserved, centrally located, winged helix DNA binding domain as well as a dimerization domain located in the C-terminal

characterization of seven human forkhead proteins: binding site specificity and DNA bending". The EMBO Journal. 13 (20): 5002–12. doi:10.1002/j.1460-2075.1994

analyses of Anzick-1's ancient nuclear, mitochondrial, and Y-chromosome DNA reveal that Anzick-1 is closely related to some modern Native American populations

nuclear DNA, supported Glires as a sister of Euarchonta to form Euarchontoglires, but some genetic data from both nuclear and mitochondrial DNA have been

large DNA-binding domain, generally comprising about a third of the entire protein that is both necessary and sufficient for sequence-specific DNA binding

Non-homologous end joining (NHEJ) is a pathway that repairs double-strand breaks in DNA. NHEJ is referred to as "non-homologous" because the break ends are directly

forkhead/winged helix transcription factor family. Checkpoints are eukaryotic DNA damage-inducible cell cycle arrests at G1 and G2. Checkpoint suppressor 1

member of a phylogenetically conserved family of proteins that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved

strand transfer. Transposase then binds to the DNA strand and creates a clamp over the transposon end of the DNA and inserts into the active site. Once the

DNA tumor viruses. The E2F proteins contain several evolutionarily conserved domains found in most members of the family. These domains include a DNA

a transcription factor that is a member of the leucine zipper family of DNA-binding proteins. This protein binds to the cAMP-responsive element (CRE)

Protein reversionless 3-like (REV3L) also known as DNA polymerase zeta catalytic subunit (POLZ) is an enzyme that in humans is encoded by the REV3L gene

opposite chromatid by the single-stranded DNA from one end of the break. Next, the 3' end of the invading DNA primes DNA synthesis, causing displacement of the

angle)—known as "tunnel vision". With the advent of and improvements to DNA testing/DNA profiling and other forensics technology, many cold cases are being

S and G2 phases. During interphase, the cell grows (G1), replicates its DNA (S) and prepares for mitosis (G2). A cell in interphase is not simply quiescent

Weisburg WG, Barns SM, Pelletier DA, Lane DJ (January 1991). "16S ribosomal DNA amplification for phylogenetic study". Journal of Bacteriology. 173 (2):

requires dimerization with another basic helix-loop-helix protein for efficient DNA binding. [provided by RefSeq, Jul 2008]. GRCh38: Ensembl release 89: ENSG00000125878

up DNA. The methylated DNA is prone to breakage, and RNA and protein synthesis is inhibited. Proliferating cancer cells need to replicate their DNA and

encoded by the CREB1 gene. This protein binds the cAMP response element, a DNA nucleotide sequence present in many viral and cellular promoters. The binding

Mad, Mxl1 and Myc. The homodimers and heterodimers compete for a common DNA target site (the E-box) in a gene promoter zone. Rearrangement of dimers

loop. The DBD of each HSF1 monomer recognizes the sequence nGAAn on target DNA. Repeated sequences of the nGAAn pentamer constitute heat shock elements

is a protein coding gene. In humans, it encodes for the protein known as DNA-binding protein inhibitor ID-4. This protein is known to be involved in the

Marmorstein R (1998). "Structures of SAP-1 bound to DNA targets from the E74 and c-fos promoters: insights into DNA sequence discrimination by Ets proteins". Mol

diameter is around 60 nm. The genome is non segmented, linear double stranded DNA and ~25.5 kilobases in length. It has a guanine + cytosine content of 42%

DNA strand inside a capsid. An appendage protrudes from each end of the cylindrical virion. The viral genome is positive-sense, single-stranded DNA ((+)ssDNA)

chromosomes of most eukaryotes. Telomeres protect the end of the chromosome from DNA damage or from fusion with neighbouring chromosomes. The fruit fly Drosophila

Upper Paleolithic period. In the United States, levels of what commercial DNA companies mark as Indigenous American ancestry (distinct from Native American

into different genomic locations (transposon) by converting RNA back into DNA through the reverse transcription process using an RNA transposition intermediate

anaemia (FA) is a rare, AR, genetic disease resulting in impaired response to DNA damage in the FA/BRCA pathway. Although it is a very rare disorder, study

Highlands ? Dani languages Dani proper Grand Valley Dani Language codes ISO 639-3 Variously: dni – Lower dnt – Mid dna – Upper hap – Hupla Glottolog gran1246

gene is a bZIP transcription factor that can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins

Arfiviricetes is a class of viruses. The following orders are recognized: Baphyvirales Cirlivirales Cremevirales Mulpavirales Recrevirales Rivendellvirales

DNA-binding protein RFX5 is a protein that in humans is encoded by the RFX5 gene. A lack of MHC-II expression results in a severe immunodeficiency syndrome

most myogenic precursor cells during the process of myogenesis. When the DNA coding for myogenin was knocked out of the mouse genome, severe skeletal

transcription of ADH5/FDH by interacting with the zinc finger and interfering with DNA binding activity of Sp1". J. Biol. Chem. 277 (30): 26761–8. doi:10.1074/jbc

of the various ethnic groups in the Philippines. The results of a massive DNA study conducted by the National Geographic's, "The Genographic Project",

angle)—known as "tunnel vision". With the advent of and improvements to DNA testing/DNA profiling and other forensics technology, many cold cases are being

Bidensovirus is a genus of single stranded DNA viruses that infect invertebrates. The species in this genus were originally classified in the family Parvoviridae

ZNF300 gene. The protein encoded by this gene is a C2H2-type zinc finger DNA binding protein and a likely transcription factor. It is antisense to the

forkhead/winged helix transcription factor family. Checkpoints are eukaryotic DNA damage-inducible cell cycle arrests at G1 and G2. Checkpoint suppressor 1

DNA (dsDNA) breaks and reseals them after managing torsion of DNA supercoils. Anthracyclines intercalated into DNA, form a stable anthracycline-DNA-topoisomerase

information, such as the amino-acid sequences of proteins or the nucleotides of DNA and/or RNA sequences. A BLAST search enables a researcher to compare a subject

chemotherapeutic agents for treatment of cancer. Nitrogen mustards are nonspecific DNA alkylating agents. During World War II nitrogen mustards were studied at

contain several functional domains including a nuclear export signal, a DNA-binding domain, a C-terminal IRF association domain and several regulatory

Gene ontology Molecular function DNA binding double-stranded DNA binding transcription factor binding protein dimerization activity RNA polymerase II

researchers used EEC-patient-derived skin keratinocytes carrying heterozygous p63 DNA-binding domain mutations as the cellular model to characterize the global

Cleary ML (September 1992). "Hlf, a novel hepatic bZIP protein, shows altered DNA-binding properties following fusion to E2A in t(17;19) acute lymphoblastic

ZBTB33 gene. This gene encodes a transcriptional regulator with bimodal DNA-binding specificity, which binds to methylated CGCG and also to the non-methylated

8-Oxoguanine glycosylase, also known as OGG1, is a DNA glycosylase enzyme that, in humans, is encoded by the OGG1 gene. It is involved in base excision

relaxation of chromosomal DNA is required for transcription of genes required for aerobic growth, while the opposite is true for DNA gyrase. Additionally,

transcription of ADH5/FDH by interacting with the zinc finger and interfering with DNA binding activity of Sp1". J. Biol. Chem. 277 (30): 26761–8. doi:10.1074/jbc

the untrained leg, had significant DNA methylation changes at 4,919 sites across the genome. The sites of altered DNA methylation were predominantly in

Protein reversionless 3-like (REV3L) also known as DNA polymerase zeta catalytic subunit (POLZ) is an enzyme that in humans is encoded by the REV3L gene

can be independently uninstalled. The first version of the DNA made it possible to keep the DNA application installed and yet temporarily stopped until the

characterization of p52, the fifth subunit of the core of the transcription/DNA repair factor TFIIH". EMBO J. 16 (5): 1093–102. doi:10.1093/emboj/16.5.1093

Kolluri R, Kinniburgh AJ (1991). "Full length cDNA sequence encoding a nuclease-sensitive element DNA binding protein". Nucleic Acids Res. 19 (17): 4771

Anzick-1 skeletal remains. They sequenced the mitochondrial DNA (mtDNA), the full nuclear DNA, and the Y-chromosome, and compared these sequences to those

retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements

catalyzes the chemical reaction ATP + [DNA-directed RNA polymerase] ⇌ {\displaystyle \rightleftharpoons } ADP + phospho-[DNA-directed RNA polymerase] Thus, the

zinc finger proteins subclass of the Gli family. They are characterized as DNA-binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling

DNA-directed RNA polymerase, mitochondrial is an enzyme that in humans is encoded by the POLRMT gene. This gene encodes a mitochondrial DNA-directed RNA

M, Pollock R, Treisman R (December 1988). "Isolation and properties of cDNA clones encoding SRF, a transcription factor that binds to the c-fos serum

full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis

family of DNA binding regulatory proteins is the myocyte-specific enhancer factor-2 (MEF2) family. Each of these proteins binds to the MEF2 target DNA sequence

Esteban-Gamboa A, Rey-Campos J (Jun 2000). "FHX, a novel fork head factor with a dual DNA binding specificity". J Biol Chem. 275 (17): 12909–16. doi:10.1074/jbc.275

Regulatory factor X, 6 also known as DNA-binding protein RFX6 is a protein that in humans is encoded by the RFX6 gene. The nuclear protein encoded by

protein 2 (SATB2) also known as DNA-binding protein SATB2 is a protein that in humans is encoded by the SATB2 gene. SATB2 is a DNA-binding protein that specifically

(2016), and "Sweet Melody" (2021). The group have released six studio albums DNA (2012), Salute (2013), Get Weird (2015), Glory Days (2016), LM5 (2018) and

DNA-binding protein inhibitor ID-1 is a protein that in humans is encoded by the ID1 gene. The protein encoded by this gene is a helix-loop-helix (HLH)