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Longer titles found: Signal transduction inhibitor (view), Journal of Receptors and Signal Transduction (view), Division of Signal Transduction Therapy (view), Sugar signal transduction (view)

searching for Signal transduction 229 found (4922 total)

alternate case: signal transduction

Nucleotidase (360 words) [view diff] exact match in snippet view article find links to article

involved predominantly in the salvage of preformed nucleotides and in signal transduction cascades involving purinergic receptors. Soluble 5'-nucleotidases
RHOBTB1 (513 words) [view diff] exact match in snippet view article find links to article
C-terminal region. The protein plays a role in small GTPase-mediated signal transduction and the organization of the actin filament system. Alternate transcriptional
Interleukin 27 (668 words) [view diff] no match in snippet view article find links to article
Interleukin 27 (IL-27) is a member of the IL-12 cytokine family. It is a heterodimeric cytokine that is composed of two distinct genes, Epstein-Barr virus-induced
GPR52 (272 words) [view diff] exact match in snippet view article find links to article
G protein-coupled receptor (GPR) family play important roles in signal transduction from the external environment to the inside of the cell.[supplied
Granulocyte-macrophage colony-stimulating factor receptor (2,654 words) [view diff] exact match in snippet view article find links to article
with the ligand only with low affinity. The β chain is involved in signal transduction and formation of high affinity receptor complex together with α chain
MYO9B (830 words) [view diff] exact match in snippet view article find links to article
protein signal transduction • regulation of small GTPase mediated signal transductionsignal transduction • Rho protein signal transduction Sources:Amigo
CD53 (995 words) [view diff] exact match in snippet view article find links to article
by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation
TAS1R2 (1,144 words) [view diff] exact match in snippet view article find links to article
chemical stimulus involved in sensory perception of sweet taste • signal transduction • response to stimulus • G protein-coupled receptor signaling pathway
P2Y receptor (1,874 words) [view diff] exact match in snippet view article find links to article
disulfide bonds have been shown to be involved in ligand binding and signal transduction. In addition, several polar residues found within the transmembrane
CAPN5 (633 words) [view diff] exact match in snippet view article find links to article
gene. Calpains are calcium-dependent cysteine proteases involved in signal transduction in a variety of cellular processes. A functional calpain protein
HRAS (1,330 words) [view diff] exact match in snippet view article find links to article
the cell's plasma membrane. Once activated, receptors stimulate signal transduction events in the cytoplasm, a process by which proteins and second messengers
TAS1R1 (1,283 words) [view diff] exact match in snippet view article find links to article
membrane Biological process • sensory perception of umami taste • signal transduction • response to stimulus • sensory perception of taste • G protein-coupled
RhoD (837 words) [view diff] case mismatch in snippet view article find links to article
2004). "Human CNK1 Acts as a Scaffold Protein, Linking Rho and Ras Signal Transduction Pathways". Mol. Cell. Biol. United States. 24 (4): 1736–46. doi:10
SH3BP2 (88 words) [view diff] exact match in snippet view article find links to article
SH3BP2 binds differentially to the SH3 domains of certain proteins of signal transduction pathways. It binds to phosphatidylinositols linking the hemopoietic
Turanose (229 words) [view diff] exact match in snippet view article find links to article
intracellular carbohydrate signaling. In addition to its involvement in signal transduction, d-(+)-turanose can also be used as a carbon source by many organisms
Coagulation factor II receptor (2,272 words) [view diff] exact match in snippet view article find links to article
reproduction, thus resensitizing the cell to thrombin and resetting the signal transduction pathway. Finding selective agonists for PAR1 has also been a topic
Interleukin 12 (1,471 words) [view diff] exact match in snippet view article find links to article
lymphocytes. There also seems to be a link between IL-2 and the signal transduction of IL-12 in NK cells. IL-2 stimulates the expression of two IL-12
Latrophilin 2 (576 words) [view diff] exact match in snippet view article find links to article
receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage
TAS1R3 (1,515 words) [view diff] exact match in snippet view article find links to article
chemical stimulus involved in sensory perception of sweet taste • signal transduction • response to stimulus • G protein-coupled receptor signaling pathway
Microtubule organizing center (1,098 words) [view diff] exact match in snippet view article find links to article
organization during plant cell mitosis. The MTOC reorients itself during signal transduction, primarily during wound repair or immune responses. The MTOC is relocalized
Protein kinase D1 (1,278 words) [view diff] exact match in snippet view article find links to article
D (PKD) family function in many extracellular receptor-mediated signal transduction pathways. The PRKCM gene encodes a cytosolic serine-threonine kinase
HBx (1,553 words) [view diff] exact match in snippet view article find links to article
protein. It is 154 amino acids long and interferes with transcription, signal transduction, cell cycle progress, protein degradation, apoptosis and chromosomal
EBF1 (1,189 words) [view diff] exact match in snippet view article find links to article
expression of key proteins required for B cell differentiation, signal transduction and function. The crucial role of this factor is shown in the regulation
Glucagon receptor (1,411 words) [view diff] exact match in snippet view article find links to article
upon binding with the signaling molecule glucagon, initiates a signal transduction pathway that begins with the activation of adenylate cyclase, which
GNAI1 (1,434 words) [view diff] no match in snippet view article find links to article
Nirenberg M (Aug 1987). "Human cDNA clones for an alpha subunit of Gi signal-transduction protein". Proceedings of the National Academy of Sciences of the
PDE4B (1,402 words) [view diff] exact match in snippet view article find links to article
concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Alternate
Dario Alessi (629 words) [view diff] case mismatch in snippet view article find links to article
Phosphorylation and Ubiquitylation Unit (MRC PPU) and Professor of Signal Transduction, at the School of Life Sciences, University of Dundee. He attended
Interleukin-1 receptor (231 words) [view diff] exact match in snippet view article find links to article
transmembrane protein that interacts with IL-1R and is required for IL-1 signal transduction. Kuno K, Matsushima K (1994). "The IL-1 receptor signaling pathway"
GNAI1 (1,434 words) [view diff] no match in snippet view article find links to article
Nirenberg M (Aug 1987). "Human cDNA clones for an alpha subunit of Gi signal-transduction protein". Proceedings of the National Academy of Sciences of the
Pulvinus (863 words) [view diff] exact match in snippet view article find links to article
light signal transduction through phytochrome. Thigmonastic movements (touch response) appear to be regulated through electrical and chemical signal transduction
Retinoic acid-inducible orphan G protein-coupled receptor (370 words) [view diff] exact match in snippet view article find links to article
provide a mechanism by which retinoic acid can influence G protein signal transduction cascades. In addition, RAIG receptors interact with members of the
Lipid raft (6,338 words) [view diff] exact match in snippet view article find links to article
to promote kinetically favorable interactions necessary for the signal transduction. Lipid rafts influence membrane fluidity and membrane protein trafficking
Insulin receptor (3,712 words) [view diff] exact match in snippet view article find links to article
activated via phosphorylation. The activated IRS-1 initiates the signal transduction pathway and binds to phosphoinositide 3-kinase (PI3K), in turn causing
BCR (gene) (1,461 words) [view diff] exact match in snippet view article
pathway • regulation of Rho protein signal transduction • regulation of small GTPase mediated signal transduction • negative regulation of inflammatory
B-cell receptor (2,133 words) [view diff] exact match in snippet view article find links to article
crucial functions upon interaction with the antigen. One function is signal transduction, involving changes in receptor oligomerization. The second function
Guanosine (350 words) [view diff] exact match in snippet view article find links to article
proteins, photosynthesis, muscle contraction, and intracellular signal transduction (cGMP). When guanine is attached by its N9 nitrogen to the C1 carbon
Vasopressin receptor (927 words) [view diff] exact match in snippet view article find links to article
subtypes. These three subtypes differ in localization, function and signal transduction mechanisms. There are three subtypes of vasopressin receptor: V1A
PTPRJ (1,309 words) [view diff] exact match in snippet view article find links to article
dephosphorylate PDGF beta receptor, and may be involved in UV-induced signal transduction. PTPRJ has been shown to interact with CTNND1. GRCh38: Ensembl release
KHDRBS1 (2,809 words) [view diff] exact match in snippet view article find links to article
KH domain-containing, RNA-binding, signal transduction-associated protein 1 is a protein that in humans is encoded by the KHDRBS1 gene. This gene encodes
Paraptosis (2,668 words) [view diff] exact match in snippet view article find links to article
paraptosis has been determined to be mediated through two positive signal transduction pathways, MAPK and JNK, by using IGF-IR at the receptor level. As
GNA11 (882 words) [view diff] exact match in snippet view article find links to article
et al. (2002). "Multiplicity of mechanisms of serotonin receptor signal transduction". Pharmacol. Ther. 92 (2–3): 179–212. doi:10.1016/S0163-7258(01)00169-3
TSPAN31 (596 words) [view diff] exact match in snippet view article find links to article
by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation
List of Nature Research journals (594 words) [view diff] case mismatch in snippet view article find links to article
American Scientific American Mind Scientific Data Scientific Reports Signal Transduction and Targeted Therapy Spinal Cord Spinal Cord Series and Cases Translational
Mucin 17 (429 words) [view diff] exact match in snippet view article find links to article
cells to provide cytoprotection, maintain luminal structure, provide signal transduction, and confer antiadhesive properties upon cancer cells that lose their
RHOBTB2 (709 words) [view diff] exact match in snippet view article find links to article
signal transduction • small GTPase mediated signal transduction • cell morphogenesis • actin filament organization • Rho protein signal transduction
CAMK1D (167 words) [view diff] exact match in snippet view article find links to article
in the regulation of granulocyte function through the chemokine signal transduction pathway. Alternatively spliced transcript variants encoding different
RGS11 (495 words) [view diff] exact match in snippet view article find links to article
heterotrimeric, signal-transducing G proteins. This protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby
CAMK1D (167 words) [view diff] exact match in snippet view article find links to article
in the regulation of granulocyte function through the chemokine signal transduction pathway. Alternatively spliced transcript variants encoding different
TSPAN31 (596 words) [view diff] exact match in snippet view article find links to article
by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation
TSPAN2 (375 words) [view diff] exact match in snippet view article find links to article
by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation
CCBP2 (1,105 words) [view diff] exact match in snippet view article find links to article
protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the
RAB23 (790 words) [view diff] exact match in snippet view article find links to article
superfamily, Rab family. It may be involved in small GTPase mediated signal transduction and intracellular protein transportation. RAB23 is an essential negative
RGS11 (495 words) [view diff] exact match in snippet view article find links to article
heterotrimeric, signal-transducing G proteins. This protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby
Guard cell (3,473 words) [view diff] exact match in snippet view article find links to article
cellular responses resulting in stomatal opening or closure. These signal transduction pathways determine for example how quickly a plant will lose water
Growth hormone–releasing hormone (1,223 words) [view diff] no match in snippet view article find links to article
Growth hormone–releasing hormone (GHRH), also known as somatocrinin or by several other names in its endogenous forms and as somatorelin (INN) in its pharmaceutical
Interleukin 10 receptor, beta subunit (975 words) [view diff] exact match in snippet view article find links to article
and IL10RA proteins has been shown to be required for IL10-induced signal transduction. This gene and three other interferon receptor genes, IFNAR2, IFNAR1
Rnd2 (850 words) [view diff] exact match in snippet view article find links to article
mediated signal transduction • positive regulation of collateral sprouting • signal transduction • actin filament organization • Rho protein signal transduction
CXCR3 (1,839 words) [view diff] exact match in snippet view article find links to article
signaling • positive regulation of transcription by RNA polymerase II • signal transduction • apoptotic process • chemotaxis • G protein-coupled receptor signaling
TSPAN13 (606 words) [view diff] exact match in snippet view article find links to article
by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation
GNAI2 (1,483 words) [view diff] exact match in snippet view article find links to article
characterization of the human gene for the alpha-subunit of Gi2, a GTP-binding signal transduction protein". FEBS Letters. 232 (2): 333–40. doi:10.1016/0014-5793(88)80764-6
GNB3 (954 words) [view diff] exact match in snippet view article find links to article
are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. A single-nucleotide polymorphism (C825T)
RAF kinase (521 words) [view diff] exact match in snippet view article find links to article
Accelerated Fibrosarcoma. RAF kinases participate in the RAS-RAF-MEK-ERK signal transduction cascade, also referred to as the mitogen-activated protein kinase
MS4A7 (532 words) [view diff] exact match in snippet view article find links to article
lineage, and it may be a component of a receptor complex involved in signal transduction. This gene is localized to 11q12, in a cluster of other family members
Oncostatin M (4,152 words) [view diff] exact match in snippet view article find links to article
of the leukemia inhibitory factor receptor and gp130 cooperate in signal transduction in hepatic and neuronal cells". Mol. Cell. Biol. 14 (1): 138–46.
TSPAN6 (513 words) [view diff] exact match in snippet view article find links to article
by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation
RAC3 (1,368 words) [view diff] exact match in snippet view article find links to article
of small GTPase mediated signal transduction • actin cytoskeleton organization • small GTPase mediated signal transduction • cell morphogenesis • actin
Axoplasm (1,231 words) [view diff] no match in snippet view article find links to article
Axoplasm is the cytoplasm within the axon of a neuron (nerve cell). For some neuronal types this can be more than 99% of the total cytoplasm. Axoplasm
MS4A3 (596 words) [view diff] exact match in snippet view article find links to article
and nonlymphoid tissues. This family member likely plays a role in signal transduction and may function as a subunit associated with receptor complexes
Epstein–Barr virus latent membrane protein 1 (505 words) [view diff] exact match in snippet view article find links to article
recognition site for cellular adaptors to bind and trigger a series of signal transduction pathways that can lead to a change in gene expression. LMP-1 is a
Tropism (713 words) [view diff] exact match in snippet view article find links to article
sensation to a stimulus, which is usually beneficial to the plant. Next, signal transduction occurs. And finally, the directional growth response occurs. Tropisms
Calcium-sensing receptor (2,477 words) [view diff] exact match in snippet view article find links to article
behavior • calcium ion import • anatomical structure morphogenesis • signal transduction • detection of calcium ion • G protein-coupled receptor signaling
MAPKAPK5 (753 words) [view diff] exact match in snippet view article find links to article
autophosphorylation • Ras protein signal transduction • regulation of translation • signal transduction • regulation of signal transduction by p53 class mediator
TSPAN4 (655 words) [view diff] exact match in snippet view article find links to article
by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation
ICAM-1 (2,309 words) [view diff] exact match in snippet view article find links to article
responses, it has been hypothesized that ICAM-1 could function in signal transduction. ICAM-1 ligation produces proinflammatory effects such as inflammatory
UPK1A (724 words) [view diff] exact match in snippet view article find links to article
by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation
Downstream (159 words) [view diff] exact match in snippet view article find links to article
temporal and mechanistic order of cellular and molecular events of signal transduction In entertainment: Downstream (novella), a novella by Joris-Karl Huysmans
KSR1 (538 words) [view diff] exact match in snippet view article find links to article
Rubin GM (Jan 1996). "KSR, a novel protein kinase required for RAS signal transduction". Cell. 83 (6): 879–88. doi:10.1016/0092-8674(95)90204-X. PMID 8521512
Chemotaxis (6,811 words) [view diff] exact match in snippet view article find links to article
turning point in understanding the whole process of intracellular signal transduction of bacteria. Some bacteria, such as E. coli, have several flagella
Janus kinase 1 (2,341 words) [view diff] exact match in snippet view article find links to article
(August 2000). "A Stat3-interacting protein (StIP1) regulates cytokine signal transduction". Proc. Natl. Acad. Sci. U.S.A. 97 (18): 10120–5. Bibcode:2000PNAS
TNK2 (1,733 words) [view diff] exact match in snippet view article find links to article
Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been
IRAK2 (701 words) [view diff] exact match in snippet view article find links to article
"Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction". Nature. 413 (6851): 78–83. Bibcode:2001Natur.413...78F. doi:10
DGKD (612 words) [view diff] exact match in snippet view article find links to article
protein, and so it is thought to play an important role in cellular signal transduction. Alternative splicing results in two transcript variants encoding
AKR1B1 (1,777 words) [view diff] exact match in snippet view article find links to article
alcohol. The involvement of AKR1B1 in oxidative stress diseases, cell signal transduction, and cell proliferation process endows AKR1B1 with potential as a
Tyrosine phosphorylation (1,995 words) [view diff] exact match in snippet view article find links to article
called tyrosine kinases. Tyrosine phosphorylation is a key step in signal transduction and the regulation of enzymatic activity. In the summer of 1979,
Janus kinase 3 (4,854 words) [view diff] exact match in snippet view article find links to article
produced by the cells of hematopoietic origin use Jak kinases for signal transduction in both immune and nonimmune cells. Among Jaks, Jak3 is widely expressed
TSPAN7 (922 words) [view diff] exact match in snippet view article find links to article
by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation
RGS5 (1,030 words) [view diff] exact match in snippet view article find links to article
RGS5 gene. The regulator of G protein signaling (RGS) proteins are signal transduction molecules that have structural homology to SST2 of Saccharomyces
RhoH (1,024 words) [view diff] exact match in snippet view article find links to article
projection Biological process • regulation of small GTPase mediated signal transduction • regulation of transcription, DNA-templated • negative regulation
SOCS2 (1,047 words) [view diff] exact match in snippet view article find links to article
Kelly PA; Edery M (1999). "Inhibition and restoration of prolactin signal transduction by suppressors of cytokine signaling". J. Biol. Chem. 274 (35): 24497–502
Molecular Cell (217 words) [view diff] exact match in snippet view article find links to article
replication, recombination and repair, structure, chaperones, receptors, signal transduction, cell cycle, metabolism, and tumorigenesis. The majority of papers
SHC1 (1,641 words) [view diff] exact match in snippet view article find links to article
transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction". Cell. 70 (1): 93–104. doi:10.1016/0092-8674(92)90536-L. PMID 1623525
Janus kinase 2 (3,222 words) [view diff] exact match in snippet view article find links to article
because the receptors for these growth factors require JAK2 for signal transduction. An inhibitor of JAK2-STAT5, AZD1480, was pointed as having activity
DGKQ (575 words) [view diff] exact match in snippet view article find links to article
phosphatidylinositol (PI) from diacylglycerol in the PI-cycle during cell signal transduction. DGKQ has been shown to interact with RHOA. GRCh38: Ensembl release
MAP3K8 (1,565 words) [view diff] exact match in snippet view article find links to article
"A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway". Nature Cell Biology. 6 (2): 97–105. doi:10.1038/ncb1086
DGKZ (929 words) [view diff] exact match in snippet view article find links to article
regulating diacylglycerol levels in intracellular signaling cascade and signal transduction. Alternative splicing occurs at this locus and three transcript variants
Necrosis (2,869 words) [view diff] exact match in snippet view article find links to article
fatal. Cellular death due to necrosis does not follow the apoptotic signal transduction pathway, but rather various receptors are activated and result in
Latrophilin 1 (681 words) [view diff] exact match in snippet view article find links to article
receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage
FLOT2 (1,340 words) [view diff] exact match in snippet view article find links to article
receptors linked to signal transduction pathways. Flot-2 binds to PAR-1, a known upstream mediator of major signal transduction pathways implicated in
MAPK7 (1,474 words) [view diff] exact match in snippet view article find links to article
Dixon JE (Jun 1995). "Components of a new human protein kinase signal transduction pathway". J. Biol. Chem. 270 (21): 12665–9. doi:10.1074/jbc.270.21
GPR174 (228 words) [view diff] exact match in snippet view article find links to article
Biological process • signal transduction • G protein-coupled receptor signaling pathway • positive regulation of Rho protein signal transduction • T cell homeostasis
Upstream (118 words) [view diff] exact match in snippet view article find links to article
temporal and mechanistic order of cellular and molecular events of signal transduction Upstream collection, a set of NSA internet surveillance programs
HER2/neu (3,910 words) [view diff] exact match in snippet view article find links to article
axon guidance • enzyme linked receptor protein signaling pathway • signal transduction • positive regulation of cell adhesion • positive regulation of protein
MAP2K5 (1,233 words) [view diff] exact match in snippet view article find links to article
Dixon JE (May 1995). "Components of a new human protein kinase signal transduction pathway". The Journal of Biological Chemistry. 270 (21): 12665–9
GPR20 (195 words) [view diff] exact match in snippet view article find links to article
membrane • membrane Biological process • signal transduction • positive regulation of Rho protein signal transduction • positive regulation of cytosolic calcium
TRAF3 (2,048 words) [view diff] exact match in snippet view article find links to article
mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR
GPS1 (906 words) [view diff] exact match in snippet view article find links to article
This gene is known to suppress G-protein and mitogen-activated signal transduction in mammalian cells. The encoded protein shares significant similarity
CD30 (1,611 words) [view diff] exact match in snippet view article find links to article
TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. It is a positive regulator
RGS3 (956 words) [view diff] exact match in snippet view article find links to article
is a GTP-ase activating protein which inhibits G-protein mediated signal transduction. The protein is largely cytosolic, but G-protein activation leads
Neuroblastoma RAS viral oncogene homolog (1,196 words) [view diff] exact match in snippet view article find links to article
Mutation-positive Melanoma McCormick F (1996). "Ras-related proteins in signal transduction and growth control". Mol. Reprod. Dev. 42 (4): 500–6. doi:10.1002/mrd
PRKCQ (2,392 words) [view diff] exact match in snippet view article find links to article
high levels in platelets and T lymphocytes, where plays a role in signal transduction. Different subpopulations of T cells vary in their requirements of
GNAQ (1,449 words) [view diff] exact match in snippet view article find links to article
Garnovskaya MN (2002). "Multiplicity of mechanisms of serotonin receptor signal transduction". Pharmacol. Ther. 92 (2–3): 179–212. doi:10.1016/S0163-7258(01)00169-3
Palmitoylation (1,450 words) [view diff] exact match in snippet view article find links to article
β2-adrenergic receptor, and endothelial nitric oxide synthase (eNOS). In signal transduction via G protein, palmitoylation of the α subunit, prenylation of the
RAC1 (3,374 words) [view diff] exact match in snippet view article find links to article
phosphorylation • Rho protein signal transduction • regulation of lamellipodium assembly • Rac protein signal transduction • cell projection assembly •
PRKCQ (2,392 words) [view diff] exact match in snippet view article find links to article
high levels in platelets and T lymphocytes, where plays a role in signal transduction. Different subpopulations of T cells vary in their requirements of
RAC2 (1,213 words) [view diff] exact match in snippet view article find links to article
GTPase mediated signal transduction • actin cytoskeleton organization • signal transduction • small GTPase mediated signal transduction • G protein-coupled
Synapsin 2 (1,693 words) [view diff] exact match in snippet view article find links to article
nervous signal transduction across excitatory and inhibitory synapses of neurons differently and is believed to be synapse-specific. Initial signal transduction
RHOB (1,225 words) [view diff] exact match in snippet view article find links to article
GTPase mediated signal transduction • cellular response to hydrogen peroxide • apoptotic process • small GTPase mediated signal transduction • positive regulation
Stathmin (1,967 words) [view diff] exact match in snippet view article find links to article
A (August 1991). "Stathmin: a relay phosphoprotein for multiple signal transduction?". Trends in Biochemical Sciences. 16 (8): 301–5. doi:10.1016/0968-0004(91)90123-D
Linker for activation of T cells (1,791 words) [view diff] exact match in snippet view article find links to article
kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts (also
Palmitoylation (1,450 words) [view diff] exact match in snippet view article find links to article
β2-adrenergic receptor, and endothelial nitric oxide synthase (eNOS). In signal transduction via G protein, palmitoylation of the α subunit, prenylation of the
Chimerin 1 (585 words) [view diff] exact match in snippet view article find links to article
proteins. It is expressed primarily in the brain and may be involved in signal transduction. This gene encodes GTPase-activating protein for p21-rac and a phorbol
RASGRF1 (187 words) [view diff] exact match in snippet view article find links to article
process • GO:0007243 intracellular signal transduction • MAPK cascade • regulation of Rho protein signal transduction • GO:0032320, GO:0032321, GO:0032855
GUCY1A2 (417 words) [view diff] exact match in snippet view article find links to article
soluble • cytoplasm Biological process • signal transduction • GO:0007243 intracellular signal transduction • cyclic nucleotide biosynthetic process •
ABCC4 (1,477 words) [view diff] exact match in snippet view article find links to article
intracellular cyclic nucleotide levels and as a mediator of cAMP-dependent signal transduction to the nucleus. MRP4/ABCC4 also transports prostaglandins, for example
KHDRBS3 (1,104 words) [view diff] exact match in snippet view article find links to article
KH domain-containing, RNA-binding, signal transduction-associated protein 3 is a protein that in humans is encoded by the KHDRBS3 gene. KHDRBS3 has been
KCNH4 (247 words) [view diff] exact match in snippet view article find links to article
Biological process • ion transport • phosphorelay signal transduction system • signal transduction • potassium ion transmembrane transport • potassium
Caveolin 2 (1,273 words) [view diff] exact match in snippet view article find links to article
membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein
TRAF1 (2,029 words) [view diff] exact match in snippet view article find links to article
(TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and
PRKAA2 (969 words) [view diff] exact match in snippet view article find links to article
glycolytic process • macroautophagy • signal transduction • steroid biosynthetic process • regulation of signal transduction by p53 class mediator • histone-serine
PLK2 (742 words) [view diff] exact match in snippet view article find links to article
G1 phase • GO:0043148 mitotic spindle organization • Rap protein signal transduction • regulation of centriole replication • negative regulation of apoptotic
RASD2 (595 words) [view diff] exact match in snippet view article find links to article
striatum-specific mRNAs characterized to date encode components of signal transduction cascades. GRCh38: Ensembl release 89: ENSG00000100302 - Ensembl,
Hemoprotein (1,080 words) [view diff] exact match in snippet view article find links to article
modulate the activity/function of those hemeproteins, affording signal transduction. Therefore, when produced in biologic systems (cells), these gaseous
James Hoch (112 words) [view diff] exact match in snippet view article find links to article
Institute. In the last 40 years his work has focused on dissecting the signal transduction mechanism that controls sporulation in Bacillus subtilis. He introduced
Cyclic di-GMP (694 words) [view diff] exact match in snippet view article find links to article
called cyclic diguanylate and c-di-GMP) is a second messenger used in signal transduction in a wide variety of bacteria. Cyclic di-GMP is not known to be used
RsmY RNA family (392 words) [view diff] exact match in snippet view article find links to article
non-coding RNA genes, that like RsmZ, is regulated by the GacS/GacA signal transduction system in the plant-beneficial soil bacterium and biocontrol model
Cancers (journal) (147 words) [view diff] case mismatch in snippet view article
Center). The Irish Association for Cancer Research (IACR) and the Signal Transduction Society (STS) are affiliated societies. The journal is abstracted
NET1 (538 words) [view diff] exact match in snippet view article find links to article
Rho protein signal transduction • GO:0007243 intracellular signal transduction • regulation of small GTPase mediated signal transduction • regulation
Annexin A3 (820 words) [view diff] exact match in snippet view article find links to article
protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phospholipase
Angiotensin II receptor type 2 (1,900 words) [view diff] exact match in snippet view article find links to article
of metanephric glomerulus development • GO:0007243 intracellular signal transduction • kidney morphogenesis • regulation of apoptotic process • positive
Hao Wu (biochemist) (715 words) [view diff] exact match in snippet view article
Harvard Medical School. Her work focuses on molecular mechanisms of signal transduction in cell death and inflammation. She is the discoverer of signalosomes
GRLF1 (810 words) [view diff] exact match in snippet view article find links to article
DNA-templated • regulation of small GTPase mediated signal transductionsignal transduction • negative regulation of vascular permeability • GO:0032320
PRPF4B (995 words) [view diff] exact match in snippet view article find links to article
this gene is thought to be involved in pre-mRNA splicing and in signal transduction. This protein belongs to a kinase family that includes serine/arginine-rich
P2RY11 (583 words) [view diff] exact match in snippet view article find links to article
coupled, 11". van der Weyden L, Conigrave AD, Morris MB (2000). "Signal transduction and white cell maturation via extracellular ATP and the P2Y11 receptor"
Megakaryocyte-associated tyrosine kinase (1,161 words) [view diff] exact match in snippet view article find links to article
site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate
PRPF4B (995 words) [view diff] exact match in snippet view article find links to article
this gene is thought to be involved in pre-mRNA splicing and in signal transduction. This protein belongs to a kinase family that includes serine/arginine-rich
GRLF1 (810 words) [view diff] exact match in snippet view article find links to article
DNA-templated • regulation of small GTPase mediated signal transductionsignal transduction • negative regulation of vascular permeability • GO:0032320
Cancers (journal) (147 words) [view diff] case mismatch in snippet view article
Center). The Irish Association for Cancer Research (IACR) and the Signal Transduction Society (STS) are affiliated societies. The journal is abstracted
RRAD (886 words) [view diff] exact match in snippet view article find links to article
anatomical structure Biological process • signal transduction • small GTPase mediated signal transduction • regulation of high voltage-gated calcium
P2RY11 (583 words) [view diff] exact match in snippet view article find links to article
coupled, 11". van der Weyden L, Conigrave AD, Morris MB (2000). "Signal transduction and white cell maturation via extracellular ATP and the P2Y11 receptor"
Phosphatidic acid phosphatase 2c (494 words) [view diff] exact match in snippet view article find links to article
novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is similar to phosphatidic
KCNH8 (331 words) [view diff] exact match in snippet view article find links to article
plasma membrane • cell membrane Biological process • phosphorelay signal transduction system • regulation of membrane potential • potassium ion transport
COP9 signalosome complex subunit 3 (985 words) [view diff] exact match in snippet view article find links to article
possesses kinase activity that phosphorylates regulators involved in signal transduction. It phosphorylates I-kappa-B-alpha, p105, and c-Jun. It acts as a
Proto-oncogene tyrosine-protein kinase Src (2,779 words) [view diff] exact match in snippet view article find links to article
activity involved in apoptotic process • GO:0007243 intracellular signal transduction • regulation of early endosome to late endosome transport • ephrin
SH2B2 (994 words) [view diff] exact match in snippet view article find links to article
stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to Shc/Grb2. SH2B2 has been shown to interact with
Moisture stress (803 words) [view diff] exact match in snippet view article find links to article
important metabolic proteins but also in the regulation of genes for signal transduction in the water-stress response. There are four pathways that have been
STAP2 (559 words) [view diff] exact match in snippet view article find links to article
proteins that mediate the interactions linking proteins involved in signal transduction pathways. Alternative splicing results in multiple transcript variants
ROR2 (1,121 words) [view diff] exact match in snippet view article find links to article
development • cell differentiation • cell fate commitment • SMAD protein signal transduction • phosphorylation • transmembrane receptor protein tyrosine kinase
PRKCD (1,094 words) [view diff] exact match in snippet view article find links to article
signaling pathway in response to oxidative stress • termination of signal transduction • interferon-gamma-mediated signaling pathway • negative regulation
PRKCB1 (671 words) [view diff] exact match in snippet view article find links to article
"Localization of protein kinases by anchoring proteins: a theme in signal transduction". Science. 268 (5208): 247–51. doi:10.1126/science.7716516. PMID 7716516
MAP2K2 (1,195 words) [view diff] exact match in snippet view article find links to article
kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK3/ERK1.
KCNH3 (304 words) [view diff] exact match in snippet view article find links to article
plasma membrane Biological process • phosphorelay signal transduction system • signal transduction • regulation of ion transmembrane transport • regulation
AKAP13 (1,427 words) [view diff] exact match in snippet view article find links to article
PMID 11313914. Kozasa T (April 2001). "Regulation of G protein-mediated signal transduction by RGS proteins". Life Sciences. 68 (19–20): 2309–17. doi:10
Salicylic acid (2,538 words) [view diff] no match in snippet view article find links to article
Salicylic acid is an organic compound with the formula HOC6H4CO2H. A colorless solid, it is a precursor to and a metabolite of aspirin (acetylsalicylic
CD33 (684 words) [view diff] exact match in snippet view article find links to article
apparatus Biological process • cell-cell signaling • cell adhesion • signal transduction • negative regulation of cell population proliferation • regulation
GPRC5B (348 words) [view diff] exact match in snippet view article find links to article
may mediate the cellular effects of retinoic acid on the G protein signal transduction cascade. Retinoic acid-inducible orphan G protein-coupled receptor
CAMP receptor protein (521 words) [view diff] exact match in snippet view article find links to article
binding of cyclic AMP. Binding of cAMP to CRP leads to a long-distance signal transduction from the N-terminal cAMP-binding domain to the C-terminal domain
GUCY2D (435 words) [view diff] exact match in snippet view article find links to article
membrane • cell membrane Biological process • GO:0007243 intracellular signal transduction • response to stimulus • regulation of rhodopsin mediated signaling
Functional Plant Biology (156 words) [view diff] exact match in snippet view article find links to article
with their environment. Of specific interest are mechanisms and signal transduction pathways by which plants adapt to extreme environmental conditions
MAPK11 (1,209 words) [view diff] exact match in snippet view article find links to article
• GO:0007243 intracellular signal transduction • cellular response to organic substance • Ras protein signal transduction • vascular endothelial growth
VAV3 (794 words) [view diff] exact match in snippet view article find links to article
intracellular signal transduction • ephrin receptor signaling pathway • lamellipodium assembly • regulation of Rho protein signal transduction • positive
PLXNA2 (714 words) [view diff] exact match in snippet view article find links to article
plexin-A/neuropilin transmembrane receptor complexes, triggering a cellular signal transduction cascade that leads to axon repulsion. This plexin-A family member
MAPK8IP2 (1,133 words) [view diff] exact match in snippet view article find links to article
kinases. This protein thus is thought to function as a regulator of signal transduction by protein kinase cascade in brain and pancreatic beta-cells. Alternatively
Functional Plant Biology (156 words) [view diff] exact match in snippet view article find links to article
with their environment. Of specific interest are mechanisms and signal transduction pathways by which plants adapt to extreme environmental conditions
VAV1 (1,962 words) [view diff] exact match in snippet view article find links to article
pathway • regulation of Rho protein signal transduction • regulation of small GTPase mediated signal transduction • positive regulation of natural killer
KSR2 (197 words) [view diff] exact match in snippet view article find links to article
GO:0007243 intracellular signal transduction • phosphorylation • protein phosphorylation • Ras protein signal transduction • calcium-mediated signaling
CD31 (1,422 words) [view diff] exact match in snippet view article find links to article
PMID 12681475. S2CID 21470915. Newman PJ, Newman DK (2004). "Signal transduction pathways mediated by PECAM-1: new roles for an old molecule in platelet
AAA proteins (1,346 words) [view diff] exact match in snippet view article find links to article
degradation, membrane fusion, microtubule severing, peroxisome biogenesis, signal transduction and the regulation of gene expression. The AAA domain contains two
GUCY1A3 (583 words) [view diff] exact match in snippet view article find links to article
muscle • nitric oxide mediated signal transduction • positive regulation of nitric oxide mediated signal transduction • retrograde trans-synaptic signaling
George Stark (2,222 words) [view diff] exact match in snippet view article find links to article
and enzyme function and modification, interferons and cytokines, signal transduction, and gene expression. George Stark was born in New York City in 1933
Sushi domain (433 words) [view diff] no match in snippet view article find links to article
components may activate B cells through CD21. CD21 is part of a large signal-transduction complex that also involves CD19, CD81, and Leu13. Some of the proteins
GNAI3 (1,634 words) [view diff] no match in snippet view article find links to article
Perlmutter RM (Nov 1987). "A small multigene family encodes Gi signal-transduction proteins". Proceedings of the National Academy of Sciences of the
GPR68 (539 words) [view diff] exact match in snippet view article find links to article
lysophosphatidylcholine: G protein-coupled receptors and receptor-mediated signal transduction". Biochim. Biophys. Acta. 1582 (1–3): 81–8. doi:10.1016/S1388-1981(02)00140-3
RhoC (1,842 words) [view diff] exact match in snippet view article find links to article
and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton
MAP3K7IP2 (1,675 words) [view diff] exact match in snippet view article find links to article
and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKL through the activation of the receptor activator
Alpha-2A adrenergic receptor (1,244 words) [view diff] exact match in snippet view article find links to article
negative regulation of calcium ion-dependent exocytosis • Rho protein signal transduction • positive regulation of cell population proliferation • negative
Ardem Patapoutian (430 words) [view diff] exact match in snippet view article find links to article
Howard Hughes Medical Institute (HHMI). Patapoutian researches the signal transduction of sensors. He made significant contributions to the identification
Metabotropic glutamate receptor 7 (1,277 words) [view diff] exact match in snippet view article find links to article
divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and
Hedgehog (disambiguation) (209 words) [view diff] exact match in snippet view article
an anti-tank, anti-vehicle obstacle Hedgehog signaling pathway, a signal transduction pathway The Hedgehog, a 2009 French film directed by Mona Achache
TNS1 (571 words) [view diff] exact match in snippet view article find links to article
homology 2 (SH2) domain, which is often found in molecules involved in signal transduction. This protein is a substrate of calpain II. A second transcript from
Phosphoproteomics (1,535 words) [view diff] exact match in snippet view article find links to article
phosphothreonine, and phosphotyrosine-containing peptides. Intracellular signal transduction is primarily mediated by the reversible phosphorylation of various
GNB1 (1,207 words) [view diff] exact match in snippet view article find links to article
are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. This gene uses alternative polyadenylation
SOCS4 (172 words) [view diff] exact match in snippet view article find links to article
regulation of growth • negative regulation of signal transduction • GO:0007243 intracellular signal transduction • positive regulation of proteasomal ubiquitin-dependent
RAPGEF2 (854 words) [view diff] exact match in snippet view article find links to article
binding protein. Members of the RAS subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and
Pii nitrogen regulatory proteins (679 words) [view diff] exact match in snippet view article find links to article
The PII family comprises a group of widely distributed signal transduction proteins found in nearly all Bacteria and also present in Archaea and in the
GPR4 (622 words) [view diff] exact match in snippet view article find links to article
mesangial cell development • signal transduction • response to acidic pH • positive regulation of Rho protein signal transduction • positive regulation of
Sphingomyelin phosphodiesterase 1 (1,163 words) [view diff] exact match in snippet view article find links to article
region • extracellular space Biological process • termination of signal transduction • glycosphingolipid metabolic process • positive regulation of protein
LPAR4 (485 words) [view diff] exact match in snippet view article find links to article
membrane-bounded organelle Biological process • signal transduction • positive regulation of Rho protein signal transduction • positive regulation of cytosolic calcium
G3BP1 (1,172 words) [view diff] exact match in snippet view article find links to article
heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It was originally reported to bind specifically to the
VAV2 (1,055 words) [view diff] exact match in snippet view article find links to article
regulation of Rho protein signal transduction • regulation of small GTPase mediated signal transduction • cell migration • signal transduction • lamellipodium assembly
ARHGAP1 (1,256 words) [view diff] exact match in snippet view article find links to article
regulation of small GTPase mediated signal transduction • Rho protein signal transductionsignal transduction • GO:0032320, GO:0032321, GO:0032855
OCRL (1,012 words) [view diff] exact match in snippet view article find links to article
biosynthetic process • regulation of small GTPase mediated signal transductionsignal transduction • GO:0032320, GO:0032321, GO:0032855, GO:0043089, GO:0032854
OCRL (1,012 words) [view diff] exact match in snippet view article find links to article
biosynthetic process • regulation of small GTPase mediated signal transductionsignal transduction • GO:0032320, GO:0032321, GO:0032855, GO:0043089, GO:0032854
VAV2 (1,055 words) [view diff] exact match in snippet view article find links to article
regulation of Rho protein signal transduction • regulation of small GTPase mediated signal transduction • cell migration • signal transduction • lamellipodium assembly
ALS2 (902 words) [view diff] exact match in snippet view article find links to article
protein signal transduction • regulation of Rho protein signal transduction • regulation of endosome size • positive regulation of Rac protein signal transduction
RGS14 (1,160 words) [view diff] exact match in snippet view article find links to article
regulation of signal transduction • regulation of DNA-templated transcription in response to stress • negative regulation of synaptic plasticity • signal transduction
NPR1 (320 words) [view diff] exact match in snippet view article find links to article
proliferation • regulation of cardiac conduction • GO:0007243 intracellular signal transduction • positive regulation of renal sodium excretion • positive regulation
CORO2A (445 words) [view diff] exact match in snippet view article find links to article
variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 5 WD repeats
MAP3K7 (1,388 words) [view diff] exact match in snippet view article find links to article
the serine/threonine protein kinase family. This kinase mediates signal transduction induced by TGF beta and morphogenetic protein (BMP), and controls
LPAR4 (485 words) [view diff] exact match in snippet view article find links to article
membrane-bounded organelle Biological process • signal transduction • positive regulation of Rho protein signal transduction • positive regulation of cytosolic calcium
ARHGAP1 (1,256 words) [view diff] exact match in snippet view article find links to article
regulation of small GTPase mediated signal transduction • Rho protein signal transductionsignal transduction • GO:0032320, GO:0032321, GO:0032855
R gene (2,155 words) [view diff] exact match in snippet view article find links to article
conformation from ADP state to and ATP state which allows it to send as signal transduction. The activation of NLRs is yet to be completely understood, according
PRKCH (1,087 words) [view diff] exact match in snippet view article find links to article
et al. (1996). "Activation of the epidermal growth factor receptor signal transduction pathway stimulates tyrosine phosphorylation of protein kinase C delta"
GPRC5C (647 words) [view diff] exact match in snippet view article find links to article
may mediate the cellular effects of retinoic acid on the G protein signal transduction cascade. Two transcript variants encoding different isoforms have
KIT (gene) (3,746 words) [view diff] exact match in snippet view article
tyrosine kinase activity, that in turn phosphorylates and activates signal transduction molecules that propagate the signal in the cell. After activation
RhoG (2,789 words) [view diff] exact match in snippet view article find links to article
transduction • regulation of small GTPase mediated signal transduction • actin cytoskeleton organization • small GTPase mediated signal transduction
Fibroblast growth factor receptor 4 (1,288 words) [view diff] exact match in snippet view article find links to article
receptor-4 shows novel features in genomic structure, ligand binding and signal transduction". EMBO J. 11 (12): 4273–80. doi:10.1002/j.1460-2075.1992.tb05526
CNKSR1 (832 words) [view diff] exact match in snippet view article find links to article
2004). "Human CNK1 acts as a scaffold protein, linking Rho and Ras signal transduction pathways". Mol. Cell. Biol. 24 (4): 1736–46. doi:10.1128/MCB.24.4
CBLC (842 words) [view diff] exact match in snippet view article find links to article
Signal transduction protein CBL-C is a protein that in humans is encoded by the CBLC gene. CBL proteins, such as CBLC, are phosphorylated upon activation
GNB1L (566 words) [view diff] exact match in snippet view article find links to article
variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 6 WD repeats
ROCK2 (213 words) [view diff] exact match in snippet view article find links to article
regulation of protein phosphorylation • GO:0007243 intracellular signal transduction • regulation of actin cytoskeleton organization • centrosome duplication
GEM (gene) (640 words) [view diff] exact match in snippet view article
and could play a role as a regulatory protein in receptor-mediated signal transduction. Alternative splicing occurs at this locus and two transcript variants
Sigma-1 receptor (2,247 words) [view diff] exact match in snippet view article find links to article
receptors have been linked circumstantially to a wide variety of signal transduction pathways. Links between σ1 receptors and G-proteins have been suggested
Nucleoporin 93 (501 words) [view diff] exact match in snippet view article find links to article
development • positive regulation of SMAD protein signal transduction • SMAD protein signal transduction • glomerular visceral epithelial cell development
RIT2 (730 words) [view diff] exact match in snippet view article find links to article
transmission • signal transduction • MAPK cascade • maintenance of protein location in cell • regulation of endocytosis • GO:0007243 intracellular signal transduction
IGBP1 (830 words) [view diff] exact match in snippet view article find links to article
phosphorylation reaction through the BCR complex and leads to multiple signal transduction pathways. IGBP1 has been shown to interact with PPP4C, PPP6C and
Transforming protein RhoA (5,329 words) [view diff] exact match in snippet view article find links to article
attachment and detachment process found in the focal adhesion mechanism. Signal transduction pathways regulated via RhoA link plasma membrane receptors to focal
Nature Reviews Clinical Oncology (174 words) [view diff] exact match in snippet view article find links to article
care Pathology Pediatric oncology Prevention Radiotherapy Screening Signal transduction Statistics Surgical oncology Targeted therapies Indexed by ISI Nature
ERBB3 (2,748 words) [view diff] exact match in snippet view article find links to article
that allows for dimerization, phosphorylation, and activation of signal transduction. ErbB3 can heterodimerize with any of the other three ErbB family
Chimerin 2 (1,008 words) [view diff] exact match in snippet view article find links to article
intracellular signal transduction • regulation of small GTPase mediated signal transductionsignal transduction • positive regulation of signal transduction • GO:0032320