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Longer titles found: Signal transduction inhibitor (view), Journal of Receptors and Signal Transduction (view), Division of Signal Transduction Therapy (view), Insulin signal transduction pathway (view), Signal Transduction and Targeted Therapy (view), Sugar signal transduction (view)

searching for Signal transduction 221 found (5220 total)

alternate case: signal transduction

Nucleotidase (361 words) [view diff] exact match in snippet view article find links to article

involved predominantly in the salvage of preformed nucleotides and in signal transduction cascades involving purinergic receptors. Soluble 5'-nucleotidases

RHOBTB1 (527 words) [view diff] exact match in snippet view article find links to article

C-terminal region. This protein plays a role in small GTPase-mediated signal transduction and in the organization of the actin filament system. Alternative

Interleukin 27 (668 words) [view diff] no match in snippet view article find links to article

Interleukin 27 (IL-27) is a member of the IL-12 cytokine family. It is a heterodimeric cytokine that is encoded by two distinct genes, Epstein-Barr virus-induced

GPR52 (222 words) [view diff] exact match in snippet view article find links to article

G protein-coupled receptor (GPR) family play important roles in signal transduction from the external environment to the inside of the cell.[supplied

P2Y receptor (1,870 words) [view diff] exact match in snippet view article find links to article

disulfide bonds have been shown to be involved in ligand binding and signal transduction. In addition, several polar residues found within the transmembrane

Prostaglandin D2 receptor (872 words) [view diff] exact match in snippet view article find links to article

calcium ion levels through inositol phosphate. These distinctions in signal transduction pathways mediate the different effects of these PDG2 receptor subtypes

CD53 (1,041 words) [view diff] exact match in snippet view article find links to article

by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation

B-cell receptor (2,180 words) [view diff] exact match in snippet view article find links to article

receptor is composed of a membrane-bound immunoglobulin molecule and a signal transduction moiety. The former forms a type 1 transmembrane receptor protein

Granulocyte-macrophage colony-stimulating factor receptor (2,709 words) [view diff] exact match in snippet view article find links to article

with the ligand only with low affinity. The β chain is involved in signal transduction and formation of high affinity receptor complex together with α chain

HRAS (1,338 words) [view diff] exact match in snippet view article find links to article

the cell's plasma membrane. Once activated, receptors stimulate signal transduction events in the cytoplasm, a process by which proteins and second messengers

MYO9B (855 words) [view diff] exact match in snippet view article find links to article

Rho protein signal transduction regulation of small GTPase mediated signal transduction signal transduction Rho protein signal transduction Sources:Amigo

Glucagon receptor (1,332 words) [view diff] exact match in snippet view article find links to article

upon binding with the signaling molecule glucagon, initiates a signal transduction pathway that begins with the activation of adenylate cyclase, which

TAS1R1 (1,285 words) [view diff] exact match in snippet view article find links to article

plasma membrane Biological process sensory perception of umami taste signal transduction response to stimulus sensory perception of taste G protein-coupled

CAPN5 (644 words) [view diff] exact match in snippet view article find links to article

gene. Calpains are calcium-dependent cysteine proteases involved in signal transduction in a variety of cellular processes. A functional calpain protein

RhoD (846 words) [view diff] exact match in snippet view article find links to article

2004). "Human CNK1 acts as a scaffold protein, linking Rho and Ras signal transduction pathways". Molecular and Cellular Biology. 24 (4): 1736–1746. doi:10

Turanose (229 words) [view diff] exact match in snippet view article find links to article

intracellular carbohydrate signaling. In addition to its involvement in signal transduction, d-(+)-turanose can also be used as a carbon source by many organisms

Latrophilin 2 (576 words) [view diff] exact match in snippet view article find links to article

receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage

Interleukin 12 (1,578 words) [view diff] exact match in snippet view article find links to article

lymphocytes. There also seems to be a link between IL-2 and the signal transduction of IL-12 in NK cells. IL-2 stimulates the expression of two IL-12

HBx (1,563 words) [view diff] exact match in snippet view article find links to article

protein. It is 154 amino acids long and interferes with transcription, signal transduction, cell cycle progress, protein degradation, apoptosis and chromosomal

TAS1R2 (1,629 words) [view diff] exact match in snippet view article find links to article

chemical stimulus involved in sensory perception of sweet taste signal transduction response to stimulus G protein-coupled receptor signaling pathway

Sofituzumab vedotin (164 words) [view diff] exact match in snippet view article find links to article

sofituzumab vedotin may also mediate antitumor activity through signal transduction inhibition, antibody-dependent cellular cytotoxicity, and complement-dependent

Microtubule organizing center (1,113 words) [view diff] exact match in snippet view article find links to article

organization during plant cell mitosis. The MTOC reorients itself during signal transduction, primarily during wound repair or immune responses. The MTOC is relocalized

TAS2R14 (2,021 words) [view diff] exact match in snippet view article find links to article

mutagenesis. TAS2Rs activation produces modulation of a broad range of signal transduction pathways. The Gαgusducin (Gαgus), which belongs to the Gαi subfamily

Proteinase-activated receptor 1 (2,285 words) [view diff] exact match in snippet view article find links to article

reproduction, thus resensitizing the cell to thrombin and resetting the signal transduction pathway. Finding selective agonists for PAR1 has also been a topic

TAS1R3 (1,536 words) [view diff] exact match in snippet view article find links to article

chemical stimulus involved in sensory perception of sweet taste signal transduction response to stimulus G protein-coupled receptor signaling pathway

Insulin receptor (3,920 words) [view diff] exact match in snippet view article find links to article

activated via phosphorylation. The activated IRS-1 initiates the signal transduction pathway and binds to phosphoinositide 3-kinase (PI3K), in turn causing

Protein kinase D1 (1,304 words) [view diff] exact match in snippet view article find links to article

D (PKD) family function in many extracellular receptor-mediated signal transduction pathways. The PRKCM gene encodes a cytosolic serine-threonine kinase

Guanosine (356 words) [view diff] exact match in snippet view article find links to article

proteins, photosynthesis, muscle contraction, and intracellular signal transduction (cGMP). When guanine is attached by its N9 nitrogen to the C1 carbon

Fungicide (1,579 words) [view diff] no match in snippet view article find links to article

Fungicides are pesticides used to kill parasitic fungi or their spores. Fungi can cause serious damage in agriculture, resulting in losses of yield and

Fungicide (1,579 words) [view diff] no match in snippet view article find links to article

Fungicides are pesticides used to kill parasitic fungi or their spores. Fungi can cause serious damage in agriculture, resulting in losses of yield and

Interleukin-1 receptor (244 words) [view diff] exact match in snippet view article find links to article

transmembrane protein that interacts with IL-1R and is required for IL-1 signal transduction. Kuno K, Matsushima K (1994). "The IL-1 receptor signaling pathway"

Retinoic acid-inducible orphan G protein-coupled receptor (385 words) [view diff] exact match in snippet view article find links to article

provide a mechanism by which retinoic acid can influence G protein signal transduction cascades. In addition, RAIG receptors interact with members of the

Pulvinus (901 words) [view diff] exact match in snippet view article find links to article

light signal transduction through phytochrome. Touch response (thigmonastic) movements appear to be regulated through electrical and chemical signal transduction

GNB4 (671 words) [view diff] exact match in snippet view article find links to article

are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. GRCh38: Ensembl release 89: ENSG00000114450

Axoplasm (1,242 words) [view diff] no match in snippet view article find links to article

Axoplasm is the cytoplasm within the axon of a neuron (nerve cell). For some neuronal types this can be more than 99% of the total cytoplasm. Axoplasm

Linker for activation of T cells (2,288 words) [view diff] exact match in snippet view article find links to article

cells or LAT, is a protein involved in the T-cell antigen receptor signal transduction pathway which in humans is encoded by the LAT gene. Alternative splicing

KHDRBS1 (2,814 words) [view diff] exact match in snippet view article find links to article

KH domain-containing, RNA-binding, signal transduction-associated protein 1 is a protein that in humans is encoded by the KHDRBS1 gene. This gene encodes

Dario Alessi (732 words) [view diff] case mismatch in snippet view article find links to article

Phosphorylation and Ubiquitylation Unit (MRC PPU) and Professor of Signal Transduction, at the School of Life Sciences, University of Dundee. He attended

Vasopressin receptor (974 words) [view diff] exact match in snippet view article find links to article

subtypes. These three subtypes differ in localization, function and signal transduction mechanisms. There are three subtypes of vasopressin receptor: V1A

Lipid raft (6,662 words) [view diff] exact match in snippet view article find links to article

to promote kinetically favorable interactions necessary for the signal transduction. Lipid rafts influence membrane fluidity and membrane protein trafficking

PDE4B (1,450 words) [view diff] exact match in snippet view article find links to article

concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Alternate

Interleukin 10 receptor, beta subunit (964 words) [view diff] exact match in snippet view article find links to article

and IL10RA proteins has been shown to be required for IL10-induced signal transduction. This gene and three other interferon receptor genes, IFNAR2, IFNAR1

PTPRJ (1,340 words) [view diff] exact match in snippet view article find links to article

dephosphorylate PDGF beta receptor, and may be involved in UV-induced signal transduction. PTPRJ has been shown to interact with CTNND1. GRCh38: Ensembl release

Growth hormone–releasing hormone (1,289 words) [view diff] no match in snippet view article find links to article

Growth hormone–releasing hormone (GHRH), also known as somatocrinin among other names in its endogenous form and as somatorelin (INN) in its pharmaceutical

Paraptosis (2,767 words) [view diff] exact match in snippet view article find links to article

paraptosis has been determined to be mediated through two positive signal transduction pathways, MAPK and JNK, by using IGF-IR at the receptor level. As

TSPAN2 (385 words) [view diff] exact match in snippet view article find links to article

by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation

Guard cell (3,429 words) [view diff] exact match in snippet view article find links to article

cellular responses resulting in stomatal opening or closure. These signal transduction pathways determine for example how quickly a plant will lose water

RAF kinase (556 words) [view diff] exact match in snippet view article find links to article

Accelerated Fibrosarcoma. RAF kinases participate in the RAS-RAF-MEK-ERK signal transduction cascade, also referred to as the mitogen-activated protein kinase

RAF kinase (556 words) [view diff] exact match in snippet view article find links to article

Accelerated Fibrosarcoma. RAF kinases participate in the RAS-RAF-MEK-ERK signal transduction cascade, also referred to as the mitogen-activated protein kinase

CXCR3 (2,039 words) [view diff] exact match in snippet view article find links to article

signaling positive regulation of transcription by RNA polymerase II signal transduction apoptotic process chemotaxis G protein-coupled receptor signaling

RHOBTB2 (688 words) [view diff] exact match in snippet view article find links to article

mediated signal transduction small GTPase mediated signal transduction cell morphogenesis actin filament organization Rho protein signal transduction cell

Guard cell (3,429 words) [view diff] exact match in snippet view article find links to article

cellular responses resulting in stomatal opening or closure. These signal transduction pathways determine for example how quickly a plant will lose water

GNAI2 (1,517 words) [view diff] exact match in snippet view article find links to article

characterization of the human gene for the alpha-subunit of Gi2, a GTP-binding signal transduction protein". FEBS Letters. 232 (2): 333–40. doi:10.1016/0014-5793(88)80764-6

RGS11 (511 words) [view diff] exact match in snippet view article find links to article

heterotrimeric, signal-transducing G proteins. This protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby

SH3BP2 (544 words) [view diff] exact match in snippet view article find links to article

to bind differentially to the SH3 domains of certain proteins of signal transduction pathways, as well as a proline-rich domain and a C-terminal Src homology

CCBP2 (1,108 words) [view diff] exact match in snippet view article find links to article

protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the

Mucin 17 (434 words) [view diff] exact match in snippet view article find links to article

cells to provide cytoprotection, maintain luminal structure, provide signal transduction, and confer antiadhesive properties upon cancer cells that lose their

Oncostatin M (4,317 words) [view diff] exact match in snippet view article find links to article

of the leukemia inhibitory factor receptor and gp130 cooperate in signal transduction in hepatic and neuronal cells". Mol. Cell. Biol. 14 (1): 138–46.

GNA11 (892 words) [view diff] exact match in snippet view article find links to article

et al. (2002). "Multiplicity of mechanisms of serotonin receptor signal transduction". Pharmacol. Ther. 92 (2–3): 179–212. doi:10.1016/S0163-7258(01)00169-3

GNB3 (960 words) [view diff] exact match in snippet view article find links to article

are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. A single-nucleotide polymorphism (C825T)

BCR (gene) (1,541 words) [view diff] exact match in snippet view article

signaling pathway regulation of Rho protein signal transduction regulation of small GTPase mediated signal transduction negative regulation of inflammatory response

RAB23 (800 words) [view diff] exact match in snippet view article find links to article

superfamily, Rab family. It may be involved in small GTPase mediated signal transduction and intracellular protein transportation. RAB23 is an essential negative

Cyclic di-GMP (935 words) [view diff] exact match in snippet view article find links to article

called cyclic diguanylate and c-di-GMP) is a second messenger used in signal transduction in a wide variety of bacteria. Cyclic di-GMP is not known to be used

MAPKAPK5 (756 words) [view diff] exact match in snippet view article find links to article

autophosphorylation Ras protein signal transduction regulation of translation signal transduction regulation of signal transduction by p53 class mediator MAPK

Rnd2 (850 words) [view diff] exact match in snippet view article find links to article

mediated signal transduction positive regulation of collateral sprouting signal transduction actin filament organization Rho protein signal transduction regulation

MS4A3 (596 words) [view diff] exact match in snippet view article find links to article

and nonlymphoid tissues. This family member likely plays a role in signal transduction and may function as a subunit associated with receptor complexes

Endocrinology (journal) (146 words) [view diff] exact match in snippet view article

emerging areas of endocrine-related research, including mechanisms of signal transduction, the biochemistry and structural biology of receptors or other signaling

CAMK1D (167 words) [view diff] exact match in snippet view article find links to article

in the regulation of granulocyte function through the chemokine signal transduction pathway. Alternatively spliced transcript variants encoding different

TNK2 (1,756 words) [view diff] exact match in snippet view article find links to article

Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been

TSPAN6 (529 words) [view diff] exact match in snippet view article find links to article

by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation

Janus kinase 1 (2,423 words) [view diff] exact match in snippet view article find links to article

(August 2000). "A Stat3-interacting protein (StIP1) regulates cytokine signal transduction". Proc. Natl. Acad. Sci. U.S.A. 97 (18): 10120–5. Bibcode:2000PNAS

TSPAN31 (599 words) [view diff] exact match in snippet view article find links to article

by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation

Janus kinase 3 (5,042 words) [view diff] exact match in snippet view article find links to article

produced by the cells of hematopoietic origin use Jak kinases for signal transduction in both immune and nonimmune cells. Among Jaks, Jak3 is widely expressed

AKR1B1 (1,825 words) [view diff] exact match in snippet view article find links to article

alcohol. The involvement of AKR1B1 in oxidative stress diseases, cell signal transduction, and cell proliferation process endows AKR1B1 with potential as a

TNK2 (1,756 words) [view diff] exact match in snippet view article find links to article

Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been

TSPAN13 (624 words) [view diff] exact match in snippet view article find links to article

by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation

Uroplakin-1a (743 words) [view diff] exact match in snippet view article find links to article

by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation

CD16 (1,844 words) [view diff] exact match in snippet view article find links to article

receptors FcγRIIIa (CD16a) and FcγRIIIb (CD16b), which participate in signal transduction. The most well-researched membrane receptor implicated in triggering

IRAK2 (704 words) [view diff] exact match in snippet view article find links to article

"Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction". Nature. 413 (6851): 78–83. Bibcode:2001Natur.413...78F. doi:10

TSPAN4 (673 words) [view diff] exact match in snippet view article find links to article

by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation

ICAM-1 (2,409 words) [view diff] exact match in snippet view article find links to article

responses, it has been hypothesized that ICAM-1 could function in signal transduction. ICAM-1 ligation produces proinflammatory effects such as inflammatory

Janus kinase 2 (3,166 words) [view diff] exact match in snippet view article find links to article

because the receptors for these growth factors require JAK2 for signal transduction. JAK2 mutation, when demonstrable, is one of the methods of diagnosing

RAC3 (1,412 words) [view diff] exact match in snippet view article find links to article

regulation of small GTPase mediated signal transduction actin cytoskeleton organization small GTPase mediated signal transduction cell morphogenesis actin filament

EBF1 (1,251 words) [view diff] exact match in snippet view article find links to article

expression of key proteins required for B cell differentiation, signal transduction and function. The crucial role of this factor is shown in the regulation

MAP2K5 (1,243 words) [view diff] exact match in snippet view article find links to article

Dixon JE (May 1995). "Components of a new human protein kinase signal transduction pathway". The Journal of Biological Chemistry. 270 (21): 12665–9

Tyrosine phosphorylation (2,100 words) [view diff] exact match in snippet view article find links to article

called tyrosine kinases. Tyrosine phosphorylation is a key step in signal transduction and the regulation of enzymatic activity. In the summer of 1979,

RhoH (1,032 words) [view diff] exact match in snippet view article find links to article

GTPase mediated signal transduction actin filament organization establishment or maintenance of cell polarity Rho protein signal transduction regulation of

KSR1 (553 words) [view diff] exact match in snippet view article find links to article

Rubin GM (Jan 1996). "KSR, a novel protein kinase required for RAS signal transduction". Cell. 83 (6): 879–88. doi:10.1016/0092-8674(95)90204-X. PMID 8521512

DGKQ (578 words) [view diff] exact match in snippet view article find links to article

phosphatidylinositol (PI) from diacylglycerol in the PI-cycle during cell signal transduction. DGKQ has been shown to interact with RHOA. GRCh38: Ensembl release

DGKD (621 words) [view diff] exact match in snippet view article find links to article

protein, and so it is thought to play an important role in cellular signal transduction. Alternative splicing results in two transcript variants encoding

SOCS2 (1,147 words) [view diff] exact match in snippet view article find links to article

Edery M (August 1999). "Inhibition and restoration of prolactin signal transduction by suppressors of cytokine signaling". The Journal of Biological

SOCS2 (1,147 words) [view diff] exact match in snippet view article find links to article

Edery M (August 1999). "Inhibition and restoration of prolactin signal transduction by suppressors of cytokine signaling". The Journal of Biological

RGS5 (1,038 words) [view diff] exact match in snippet view article find links to article

RGS5 gene. The regulator of G protein signaling (RGS) proteins are signal transduction molecules that have structural homology to SST2 of Saccharomyces

Channelopathy (1,121 words) [view diff] exact match in snippet view article find links to article

occurs it may affect the gating, conductance, ion selectivity, or signal transduction of the channel. Channelopathies can be categorized based on the organ

TSPAN7 (946 words) [view diff] exact match in snippet view article find links to article

by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation

GPS1 (915 words) [view diff] exact match in snippet view article find links to article

gene. This gene is known to inhibit G-protein and mitogen-activated signal transduction in mammalian cells. The protein encoded by this gene shares significant

DGKZ (929 words) [view diff] exact match in snippet view article find links to article

regulating diacylglycerol levels in intracellular signaling cascade and signal transduction. Alternative splicing occurs at this locus and three transcript variants

PRKCQ (2,383 words) [view diff] exact match in snippet view article find links to article

high levels in platelets and T lymphocytes, where plays a role in signal transduction. Different subpopulations of T cells vary in their requirements of

James Hoch (127 words) [view diff] exact match in snippet view article find links to article

Institute. In the last 40 years his work has focused on dissecting the signal transduction mechanism that controls sporulation in Bacillus subtilis. He introduced

SHC1 (1,641 words) [view diff] exact match in snippet view article find links to article

transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction". Cell. 70 (1): 93–104. doi:10.1016/0092-8674(92)90536-L. PMID 1623525

Neuroblastoma RAS viral oncogene homolog (1,205 words) [view diff] exact match in snippet view article find links to article

Mutation-positive Melanoma McCormick F (1996). "Ras-related proteins in signal transduction and growth control". Mol. Reprod. Dev. 42 (4): 500–6. doi:10.1002/mrd

MAP3K8 (1,632 words) [view diff] exact match in snippet view article find links to article

"A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway". Nature Cell Biology. 6 (2): 97–105. doi:10.1038/ncb1086

HER2 (4,665 words) [view diff] exact match in snippet view article find links to article

signal transduction cell differentiation negative regulation of apoptotic process positive regulation of ERK1 and ERK2 cascade intracellular signal transduction

FLOT2 (1,370 words) [view diff] exact match in snippet view article find links to article

receptors linked to signal transduction pathways. Flot-2 binds to PAR-1, a known upstream mediator of major signal transduction pathways implicated in

Synapsin 2 (1,701 words) [view diff] exact match in snippet view article find links to article

nervous signal transduction across excitatory and inhibitory synapses of neurons differently and is believed to be synapse-specific. Initial signal transduction

TRAF3 (2,200 words) [view diff] exact match in snippet view article find links to article

mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR

Hao Wu (biochemist) (792 words) [view diff] exact match in snippet view article

Harvard Medical School. Her work focuses on molecular mechanisms of signal transduction in cell death and inflammation. She is the discoverer of signalosomes

Stathmin (1,975 words) [view diff] exact match in snippet view article find links to article

A (August 1991). "Stathmin: a relay phosphoprotein for multiple signal transduction?". Trends in Biochemical Sciences. 16 (8): 301–5. doi:10.1016/0968-0004(91)90123-D

Angiotensin II receptor type 2 (1,738 words) [view diff] exact match in snippet view article find links to article

nitric oxide mediated signal transduction angiotensin-activated signaling pathway extracellular negative regulation of signal transduction vasodilation blood

RHOB (1,246 words) [view diff] exact match in snippet view article find links to article

GTPase mediated signal transduction cellular response to hydrogen peroxide apoptotic process small GTPase mediated signal transduction positive regulation

RHOB (1,246 words) [view diff] exact match in snippet view article find links to article

GTPase mediated signal transduction cellular response to hydrogen peroxide apoptotic process small GTPase mediated signal transduction positive regulation

Stathmin (1,975 words) [view diff] exact match in snippet view article find links to article

A (August 1991). "Stathmin: a relay phosphoprotein for multiple signal transduction?". Trends in Biochemical Sciences. 16 (8): 301–5. doi:10.1016/0968-0004(91)90123-D

GPR20 (198 words) [view diff] exact match in snippet view article find links to article

membrane membrane Biological process signal transduction positive regulation of Rho protein signal transduction positive regulation of cytosolic calcium

RGS3 (1,052 words) [view diff] exact match in snippet view article find links to article

is a GTP-ase activating protein which inhibits G-protein mediated signal transduction. The protein is largely cytosolic, but G-protein activation leads

Cancers (journal) (147 words) [view diff] case mismatch in snippet view article

Center). The Irish Association for Cancer Research (IACR) and the Signal Transduction Society (STS) are affiliated societies. The journal is abstracted

Palmitoylation (1,596 words) [view diff] exact match in snippet view article find links to article

β2-adrenergic receptor, and endothelial nitric oxide synthase (eNOS). In signal transduction via G protein, palmitoylation of the α subunit, prenylation of the

Chemotaxis (7,967 words) [view diff] exact match in snippet view article find links to article

turning point in understanding the whole process of intracellular signal transduction of bacteria. Some bacteria, such as E. coli, have several flagella

CD30 (1,686 words) [view diff] exact match in snippet view article find links to article

TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. It is a positive regulator

Latrophilin 1 (750 words) [view diff] exact match in snippet view article find links to article

receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage

Chimerin 1 (586 words) [view diff] exact match in snippet view article find links to article

proteins. It is expressed primarily in the brain and may be involved in signal transduction. This gene encodes GTPase-activating protein for p21-rac and a phorbol

TRAF1 (2,025 words) [view diff] exact match in snippet view article find links to article

(TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and

GRLF1 (819 words) [view diff] exact match in snippet view article find links to article

transcription, DNA-templated regulation of small GTPase mediated signal transduction signal transduction negative regulation of vascular permeability positive regulation

Moisture stress (789 words) [view diff] exact match in snippet view article find links to article

important metabolic proteins but also in the regulation of genes for signal transduction in the water-stress response. There are four pathways that have been

RASD2 (616 words) [view diff] exact match in snippet view article find links to article

striatum-specific mRNAs characterized to date encode components of signal transduction cascades. GRCh38: Ensembl release 89: ENSG00000100302 – Ensembl,

Phosphatidic acid phosphatase 2c (499 words) [view diff] exact match in snippet view article find links to article

novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is similar to phosphatidic

AKAP13 (1,459 words) [view diff] exact match in snippet view article find links to article

PMID 11313914. Kozasa T (April 2001). "Regulation of G protein-mediated signal transduction by RGS proteins". Life Sciences. 68 (19–20): 2309–17. doi:10

Proto-oncogene tyrosine-protein kinase Src (2,648 words) [view diff] exact match in snippet view article find links to article

Overview of signal transduction pathways involved in apoptosis.

ABCC4 (1,515 words) [view diff] exact match in snippet view article find links to article

intracellular cyclic nucleotide levels and as a mediator of cAMP-dependent signal transduction to the nucleus. MRP4/ABCC4 also transports prostaglandins, for example

Megakaryocyte-associated tyrosine kinase (1,177 words) [view diff] exact match in snippet view article find links to article

site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate

Caveolin 2 (1,293 words) [view diff] exact match in snippet view article find links to article

membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein

RsmY RNA family (389 words) [view diff] exact match in snippet view article find links to article

non-coding RNA genes, that like RsmZ, is regulated by the GacS/GacA signal transduction system in the plant-beneficial soil bacterium and biocontrol model

Metabotropic glutamate receptor 6 (868 words) [view diff] exact match in snippet view article find links to article

divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and

SOCS7 (642 words) [view diff] exact match in snippet view article find links to article

S2CID 40940132. Wormald S, Hilton DJ (Jan 2004). "Inhibitors of cytokine signal transduction" (PDF). The Journal of Biological Chemistry. 279 (2): 821–4. doi:10

Annexin A3 (835 words) [view diff] exact match in snippet view article find links to article

protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phospholipase

PRKAA2 (969 words) [view diff] exact match in snippet view article find links to article

glycolytic process macroautophagy signal transduction steroid biosynthetic process regulation of signal transduction by p53 class mediator regulation of

KHDRBS3 (1,258 words) [view diff] exact match in snippet view article find links to article

KH domain-containing, RNA-binding, signal transduction-associated protein 3 is a protein that in humans is encoded by the KHDRBS3 gene. KHDRBS3 has been

Necrosis (3,428 words) [view diff] exact match in snippet view article find links to article

fatal. Cellular death due to necrosis does not follow the apoptotic signal transduction pathway, but rather various receptors are activated and result in

GUCY1A2 (421 words) [view diff] exact match in snippet view article find links to article

cyclase complex, soluble cytoplasm Biological process signal transduction intracellular signal transduction cyclic nucleotide biosynthetic process cGMP biosynthetic

MAPK7 (1,995 words) [view diff] exact match in snippet view article find links to article

Dixon JE (May 1995). "Components of a new human protein kinase signal transduction pathway". The Journal of Biological Chemistry. 270 (21): 12665–12669

RAC2 (1,271 words) [view diff] exact match in snippet view article find links to article

small GTPase mediated signal transduction actin cytoskeleton organization signal transduction small GTPase mediated signal transduction G protein-coupled

GNAI3 (1,641 words) [view diff] no match in snippet view article find links to article

Perlmutter RM (Nov 1987). "A small multigene family encodes Gi signal-transduction proteins". Proceedings of the National Academy of Sciences of the

MAPK14 (5,270 words) [view diff] exact match in snippet view article find links to article

mitogen-activated protein kinase 14". Ono K, Han J (Jan 2000). "The p38 signal transduction pathway: activation and function". Cellular Signalling. 12 (1): 1–13

ROR2 (1,123 words) [view diff] exact match in snippet view article find links to article

development cell differentiation cell fate commitment SMAD protein signal transduction phosphorylation transmembrane receptor protein tyrosine kinase signaling

OR51E1 (682 words) [view diff] case mismatch in snippet view article find links to article

protein-coupled receptor for an odorant receptor". Journal of Receptor and Signal Transduction Research. 27 (4): 323–34. doi:10.1080/10799890701534180. PMID 17885925

PLXNA2 (773 words) [view diff] exact match in snippet view article find links to article

plexin-A/neuropilin transmembrane receptor complexes, triggering a cellular signal transduction cascade that leads to axon repulsion. This plexin-A family member

Calcium-sensing receptor (3,953 words) [view diff] exact match in snippet view article find links to article

chemosensory behavior calcium ion import anatomical structure morphogenesis signal transduction detection of calcium ion G protein-coupled receptor signaling pathway

MAPK11 (1,233 words) [view diff] exact match in snippet view article find links to article

gene expression intracellular signal transduction cellular response to organic substance Ras protein signal transduction vascular endothelial growth factor

PRPF4B (995 words) [view diff] exact match in snippet view article find links to article

this gene is thought to be involved in pre-mRNA splicing and in signal transduction. This protein belongs to a kinase family that includes serine/arginine-rich

RASGRF1 (187 words) [view diff] exact match in snippet view article find links to article

intracellular signal transduction MAPK cascade regulation of Rho protein signal transduction positive regulation of GTPase activity signal transduction regulation

George Stark (2,378 words) [view diff] exact match in snippet view article find links to article

and enzyme function and modification, interferons and cytokines, signal transduction, and gene expression. George Stark was born in New York City in 1933

GPR143 (1,197 words) [view diff] exact match in snippet view article find links to article

1999). "Ocular albinism: evidence for a defect in an intracellular signal transduction system". Nature Genetics. 23 (1): 108–112. doi:10.1038/12715. PMID 10471510

P2RY11 (597 words) [view diff] exact match in snippet view article find links to article

coupled, 11". van der Weyden L, Conigrave AD, Morris MB (2000). "Signal transduction and white cell maturation via extracellular ATP and the P2Y11 receptor"

GPR174 (350 words) [view diff] exact match in snippet view article find links to article

Biological process signal transduction G protein-coupled receptor signaling pathway positive regulation of Rho protein signal transduction T cell homeostasis

Phosphoproteomics (1,541 words) [view diff] exact match in snippet view article find links to article

phosphothreonine, and phosphotyrosine-containing peptides. Intracellular signal transduction is primarily mediated by the reversible phosphorylation of various

60S ribosomal protein L26 (581 words) [view diff] exact match in snippet view article find links to article

decay rRNA processing cytoplasmic translation DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest cellular response

SH2B2 (994 words) [view diff] exact match in snippet view article find links to article

stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to Shc/Grb2. SH2B2 has been shown to interact with

KCNH8 (335 words) [view diff] exact match in snippet view article find links to article

plasma membrane plasma membrane Biological process phosphorelay signal transduction system regulation of membrane potential potassium ion transport regulation

KCNH4 (251 words) [view diff] exact match in snippet view article find links to article

membrane Biological process ion transport phosphorelay signal transduction system signal transduction potassium ion transmembrane transport potassium ion

R gene (2,099 words) [view diff] exact match in snippet view article find links to article

conformation from ADP state to and ATP state which allows it to send as signal transduction. The activation of NLRs is yet to be completely understood, according

KCNH3 (306 words) [view diff] exact match in snippet view article find links to article

of plasma membrane Biological process phosphorelay signal transduction system signal transduction regulation of ion transmembrane transport regulation

RhoG (2,844 words) [view diff] exact match in snippet view article find links to article

signal transduction regulation of small GTPase mediated signal transduction actin cytoskeleton organization small GTPase mediated signal transduction neutrophil

SH2B2 (994 words) [view diff] exact match in snippet view article find links to article

stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to Shc/Grb2. SH2B2 has been shown to interact with

G3BP1 (1,149 words) [view diff] exact match in snippet view article find links to article

heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It was originally reported to bind specifically to the

PRKCD (1,096 words) [view diff] exact match in snippet view article find links to article

signaling pathway in response to oxidative stress termination of signal transduction interferon-gamma-mediated signaling pathway negative regulation of

GUCY2D (436 words) [view diff] exact match in snippet view article find links to article

outer membrane plasma membrane Biological process intracellular signal transduction response to stimulus regulation of rhodopsin mediated signaling pathway

Fibroblast growth factor receptor 4 (1,291 words) [view diff] exact match in snippet view article find links to article

receptor-4 shows novel features in genomic structure, ligand binding and signal transduction". EMBO J. 11 (12): 4273–80. doi:10.1002/j.1460-2075.1992.tb05526

RRAD (gene) (950 words) [view diff] exact match in snippet view article

intracellular anatomical structure Biological process signal transduction small GTPase mediated signal transduction regulation of high voltage-gated calcium channel

Pii nitrogen regulatory proteins (683 words) [view diff] exact match in snippet view article find links to article

The PII family comprises a group of widely distributed signal transduction proteins found in nearly all Bacteria and also present in Archaea and in the

PRKCB1 (678 words) [view diff] exact match in snippet view article find links to article

"Localization of protein kinases by anchoring proteins: a theme in signal transduction". Science. 268 (5208): 247–51. Bibcode:1995Sci...268..247M. doi:10

Functional Plant Biology (156 words) [view diff] exact match in snippet view article find links to article

with their environment. Of specific interest are mechanisms and signal transduction pathways by which plants adapt to extreme environmental conditions

RAPGEF2 (867 words) [view diff] exact match in snippet view article find links to article

binding protein. Members of the RAS subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and

MAP2K2 (1,231 words) [view diff] exact match in snippet view article find links to article

kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK3/ERK1.

MAP2K3 (1,111 words) [view diff] exact match in snippet view article find links to article

Raingeaud J, Barrett T, et al. (1995). "Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms". Science. 267 (5198): 682–5

MAPK8IP2 (1,144 words) [view diff] exact match in snippet view article find links to article

kinases. This protein thus is thought to function as a regulator of signal transduction by protein kinase cascade in brain and pancreatic beta-cells. Alternatively

CBLC (847 words) [view diff] exact match in snippet view article find links to article

Signal transduction protein CBL-C is a protein that in humans is encoded by the CBLC gene. CBL proteins, such as CBLC, are phosphorylated upon activation

COP9 signalosome complex subunit 3 (1,000 words) [view diff] exact match in snippet view article find links to article

possesses kinase activity that phosphorylates regulators involved in signal transduction. It phosphorylates I-kappa-B-alpha, p105, and c-Jun. It acts as a

Sushi domain (433 words) [view diff] no match in snippet view article find links to article

components may activate B cells through CD21. CD21 is part of a large signal-transduction complex that also involves CD19, CD81, and Leu13. Some of the proteins

GPR68 (555 words) [view diff] exact match in snippet view article find links to article

lysophosphatidylcholine: G protein-coupled receptors and receptor-mediated signal transduction". Biochim. Biophys. Acta. 1582 (1–3): 81–8. doi:10.1016/S1388-1981(02)00140-3

VAV3 (799 words) [view diff] exact match in snippet view article find links to article

intracellular signal transduction ephrin receptor signaling pathway lamellipodium assembly regulation of Rho protein signal transduction positive regulation

GPRC5B (360 words) [view diff] exact match in snippet view article find links to article

may mediate the cellular effects of retinoic acid on the G protein signal transduction cascade. Retinoic acid-inducible orphan G protein-coupled receptor

GUCY1A3 (588 words) [view diff] exact match in snippet view article find links to article

smooth muscle nitric oxide mediated signal transduction positive regulation of nitric oxide mediated signal transduction retrograde trans-synaptic signaling

Rashna Bhandari (544 words) [view diff] exact match in snippet view article find links to article

Fingerprinting and Diagnostics, Hyderabad. Bhandari is pursuing her study on signal transduction in biological systems, with particular emphasis on understanding

Chemical modification (1,476 words) [view diff] exact match in snippet view article find links to article

one of two signal transduction pathways. These pathways may either be linear or a cascade transduction pathway. Cascade signal transduction pathways lead

TIE1 (339 words) [view diff] exact match in snippet view article find links to article

angiogenesis mesoderm development signal transduction peptidyl-tyrosine phosphorylation negative regulation of signal transduction cell differentiation negative

VAV1 (1,999 words) [view diff] exact match in snippet view article find links to article

signaling pathway regulation of Rho protein signal transduction regulation of small GTPase mediated signal transduction positive regulation of natural killer

Mdm2 (4,010 words) [view diff] exact match in snippet view article find links to article

Overview of signal transduction pathways involved in apoptosis

ELK1 (2,465 words) [view diff] exact match in snippet view article find links to article

phosphorylated by MAPKs at its C-terminus. MAPKs are the final effectors of signal transduction pathways that begin at the plasma membrane. Phosphorylation by MAPKs

ARHGEF3 (551 words) [view diff] exact match in snippet view article find links to article

protein signal transduction intracellular signal transduction regulation of small GTPase mediated signal transduction Rho protein signal transduction positive

MAP3K7IP2 (1,677 words) [view diff] exact match in snippet view article find links to article

and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKL through the activation of the receptor activator

Salicylic acid (3,402 words) [view diff] no match in snippet view article find links to article

Salicylic acid is an organic compound with the formula HOC6H4COOH. A colorless (or white), bitter-tasting solid, it is a precursor to and a metabolite

ARHGAP1 (1,288 words) [view diff] exact match in snippet view article find links to article

mediated signal transduction Rho protein signal transduction signal transduction positive regulation of GTPase activity small GTPase mediated signal transduction

GPR4 (733 words) [view diff] exact match in snippet view article find links to article

mesangial cell development signal transduction response to acidic pH positive regulation of Rho protein signal transduction positive regulation of cytosolic

Kalirin (3,295 words) [view diff] exact match in snippet view article find links to article

of Rho protein signal transduction regulation of small GTPase mediated signal transduction vesicle-mediated transport signal transduction positive regulation

SOS1 (3,598 words) [view diff] exact match in snippet view article find links to article

new member of the amphiphysin family connecting endocytosis and signal transduction pathways". The Journal of Biological Chemistry. 272 (24): 15101–15105

Babraham Institute (1,012 words) [view diff] exact match in snippet view article find links to article

environment. Immunology (headed by Martin Turner): investigates signal transduction pathways that regulate the survival and activation of lymphocytes

NET1 (541 words) [view diff] exact match in snippet view article find links to article

protein signal transduction intracellular signal transduction regulation of small GTPase mediated signal transduction regulation of cell growth signal transduction

PRKCH (1,139 words) [view diff] exact match in snippet view article find links to article

et al. (1996). "Activation of the epidermal growth factor receptor signal transduction pathway stimulates tyrosine phosphorylation of protein kinase C delta"

Low-density lipoprotein receptor-related protein 8 (3,439 words) [view diff] exact match in snippet view article find links to article

low-density lipoprotein receptor family. These receptors function in signal transduction and endocytosis of specific ligands. Through interactions with one

Alpha-2A adrenergic receptor (1,303 words) [view diff] exact match in snippet view article find links to article

protein signal transduction negative regulation of lipid catabolic process activation of protein kinase activity actin cytoskeleton organization signal transduction

TNIK (749 words) [view diff] exact match in snippet view article find links to article

gene. TNIK is involved in various cellular processes, including signal transduction, gene transcription, and cytoskeletal organization. As an emerging

VAV2 (1,204 words) [view diff] exact match in snippet view article find links to article

regulation of Rho protein signal transduction regulation of small GTPase mediated signal transduction cell migration signal transduction lamellipodium assembly

GNB1 (1,276 words) [view diff] exact match in snippet view article find links to article

are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. This gene uses alternative polyadenylation

Metabotropic glutamate receptor 7 (1,359 words) [view diff] exact match in snippet view article find links to article

divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and

Gerald M. Rubin (1,585 words) [view diff] exact match in snippet view article find links to article

notable for development of genetic and genomics tools and studies of signal transduction and gene regulation. Rubin also served as a vice president of the

LPAR4 (492 words) [view diff] exact match in snippet view article find links to article

membrane-bounded organelle Biological process signal transduction positive regulation of Rho protein signal transduction positive regulation of cytosolic calcium

IGBP1 (829 words) [view diff] exact match in snippet view article find links to article

phosphorylation reaction through the BCR complex and leads to multiple signal transduction pathways. IGBP1 has been shown to interact with PPP4C, PPP6C and

LRRN2 (480 words) [view diff] exact match in snippet view article find links to article

with other proteins that function as cell-adhesion molecules or as signal transduction receptors and is a candidate for the target gene in the 1q32.1 amplicon

RIT2 (734 words) [view diff] exact match in snippet view article find links to article

transmission signal transduction MAPK cascade maintenance of protein location in cell regulation of endocytosis intracellular signal transduction regulation

NCKIPSD (986 words) [view diff] exact match in snippet view article find links to article

is localized exclusively in the cell nucleus. It plays a role in signal transduction, and may function in the maintenance of sarcomeres and in the assembly

OCRL (1,047 words) [view diff] exact match in snippet view article find links to article

biosynthetic process regulation of small GTPase mediated signal transduction signal transduction positive regulation of GTPase activity phosphatidylinositol-3-phosphate

GNAO1 (1,373 words) [view diff] exact match in snippet view article find links to article

et al. (2002). "Multiplicity of mechanisms of serotonin receptor signal transduction". Pharmacol. Ther. 92 (2–3): 179–212. doi:10.1016/S0163-7258(01)00169-3

Glypiation (746 words) [view diff] exact match in snippet view article find links to article

variation, demonstrating vast functional diversity that includes signal transduction, cell adhesion and immune recognition. GPI anchors can also be cleaved

NPR1 (321 words) [view diff] exact match in snippet view article find links to article

cell proliferation regulation of cardiac conduction intracellular signal transduction positive regulation of renal sodium excretion positive regulation

SH2D1B (541 words) [view diff] exact match in snippet view article find links to article

its free SRC (MIM 190090) homology-2 (SH2) domain, EAT2 regulates signal transduction through receptors expressed on the surface of antigen-presenting

Chimerin 2 (1,024 words) [view diff] exact match in snippet view article find links to article

intracellular signal transduction regulation of small GTPase mediated signal transduction signal transduction positive regulation of signal transduction positive

Transforming protein RhoA (5,373 words) [view diff] exact match in snippet view article find links to article

attachment and detachment process found in the focal adhesion mechanism. Signal transduction pathways regulated via RhoA link plasma membrane receptors to focal

ALS2 (905 words) [view diff] exact match in snippet view article find links to article

signal transduction regulation of Rho protein signal transduction regulation of endosome size positive regulation of Rac protein signal transduction positive

Pharmacology (5,074 words) [view diff] exact match in snippet view article find links to article

design, molecular and cellular mechanisms, organ/systems mechanisms, signal transduction/cellular communication, molecular diagnostics, interactions, chemical

EPS8 (1,480 words) [view diff] exact match in snippet view article find links to article

signal transduction signal transduction positive regulation of signal transduction cellular response to leukemia inhibitory factor Rho protein signal

IL2RB (1,698 words) [view diff] exact match in snippet view article find links to article

monomer of the alpha subunit (also called CD25) and is not involved in signal transduction. The intermediate affinity form consists of a gamma/beta subunit

Alpha-1A adrenergic receptor (1,360 words) [view diff] exact match in snippet view article find links to article

regulation of MAPK cascade intracellular signal transduction positive regulation of ERK1 and ERK2 cascade signal transduction organ growth cell-cell signaling