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searching for Janus kinase 2 8 found (39 total)

Fedratinib (690 words) [view diff] exact match in snippet view article find links to article

capsules that are taken by mouth. It is a semi-selective inhibitor of Janus kinase 2 (JAK-2). It was approved by the FDA on 16 August 2019. Myelofibrosis

Lestaurtinib (1,576 words) [view diff] exact match in snippet view article find links to article

It is an inhibitor of the kinases fms-like tyrosine kinase 3 (FLT3), Janus kinase 2 (JAK2), tropomyosin receptor kinase (trk) A (TrkA), TrkB and TrkC. Lestaurtinib

Ion transporter (2,028 words) [view diff] no match in snippet view article find links to article

Examples of the P-type ATPase include Na+/K+-ATPase that is regulated by Janus Kinase-2 as well as Ca2+ ATPase which exhibits sensitivity to ADP and ATP concentrations

Interleukin-23 receptor (1,589 words) [view diff] exact match in snippet view article find links to article

required for IL-23 signaling. This protein associates constitutively with Janus kinase 2 (JAK2) and also binds to transcription activator STAT3 in a ligand-dependent

SH2B2 (994 words) [view diff] no match in snippet view article find links to article

"Identification of SH2B2beta as an inhibitor for SH2B1- and SH2B2alpha-promoted Janus kinase-2 activation and insulin signaling". Endocrinology. 148 (4): 1615–21.

STAR (gene) (592 words) [view diff] exact match in snippet view article

Li J, Feltzer RE, Dawson KL, Hudson EA, Clark BJ (December 2003). "Janus kinase 2 and calcium are required for angiotensin II-dependent activation of

Zotiraciclib (619 words) [view diff] exact match in snippet view article find links to article

(SB1317/TG02), a potent inhibitor of cyclin dependent kinases (CDKs), Janus kinase 2 (JAK2), and fms-like tyrosine kinase-3 (FLT3) for the treatment of cancer"

Anne Rosenberg (1,716 words) [view diff] no match in snippet view article find links to article

receptor-associated tyrosine kinase, and to identify this molecule as Janus kinase-2. These human tissue lines in a prolactin deficient mouse model allowed