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Longer titles found: Programmed cell death protein 1 (view)

searching for Programmed cell death 269 found (1044 total)

Inhibitor of apoptosis (1,569 words) [view diff] exact match in snippet view article find links to article

of proteins that mainly act on the intrinsic pathway that block programmed cell death, which can frequently lead to cancer or other effects for the cell

H. Robert Horvitz (2,156 words) [view diff] exact match in snippet view article find links to article

discoveries concerning the genetic regulation of organ development and programmed cell death" were "important for medical research and have shed new light on

Protein serine/threonine phosphatase (222 words) [view diff] exact match in snippet view article find links to article

regulates many cellular pathways involved in cell proliferation, programmed cell death (apoptosis), embryonic development, and cell differentiation. There

PDCD4 (1,041 words) [view diff] exact match in snippet view article find links to article

Programmed cell death protein 4 is a protein that in humans is encoded by the PDCD4 gene. It is one of the targets of an oncomiR, MIRN21. This gene encodes

Bcl-2 family (2,148 words) [view diff] exact match in snippet view article find links to article

family is most notable for their regulation of apoptosis, a form of programmed cell death, at the mitochondrion. The Bcl-2 family proteins consists of members

Bcl-2 family (2,148 words) [view diff] exact match in snippet view article find links to article

family is most notable for their regulation of apoptosis, a form of programmed cell death, at the mitochondrion. The Bcl-2 family proteins consists of members

Bcl-xL (884 words) [view diff] exact match in snippet view article find links to article

cytochrome c, which leads to caspase activation and ultimately, programmed cell death. It is a well-established concept in the field of apoptosis that

CAMK (886 words) [view diff] exact match in snippet view article find links to article

responding genes. CAMK also works to regulate the cell life cycle (i.e. programmed cell death), rearrangement of the cell's cytoskeletal network, and mechanisms

PDCD5 (988 words) [view diff] exact match in snippet view article find links to article

Programmed cell death protein 5 is a protein, originally identified as an apoptosis-accelerating protein, that in humans is encoded by the PDCD5 gene

Elesclomol (650 words) [view diff] exact match in snippet view article find links to article

Elesclomol (INN, codenamed STA-4783) is a drug that triggers apoptosis (programmed cell death) in cancer cells. It is being developed by Synta Pharmaceuticals

PDCD10 (1,340 words) [view diff] exact match in snippet view article find links to article

Programmed cell death protein 10 is a protein that in humans is encoded by the PDCD10 gene. This gene encodes a protein, originally identified in a premyeloid

Nuclease S1 (856 words) [view diff] exact match in snippet view article find links to article

prokaryotes and eukaryotes and are thought to be associated in programmed cell death and also in tissue differentiation. Furthermore, they are secreted

TNF receptor superfamily (610 words) [view diff] exact match in snippet view article find links to article

the fact that they seemed to play an important role in apoptosis (programmed cell death), although they are now known to play other roles as well. In the

PDCD6IP (1,242 words) [view diff] exact match in snippet view article find links to article

Programmed cell death 6-interacting protein also known as ALIX is a protein that in humans is encoded by the PDCD6IP gene. This gene encodes a protein

Survivin (780 words) [view diff] exact match in snippet view article find links to article

activation, thereby leading to negative regulation of apoptosis or programmed cell death. This has been shown by disruption of survivin induction pathways

PDCD6 (1,245 words) [view diff] exact match in snippet view article find links to article

Programmed cell death protein 6 is a protein that in humans is encoded by the PDCD6 gene. This gene encodes a calcium-binding protein belonging to the

Necroptosis (1,667 words) [view diff] exact match in snippet view article find links to article

cellular damage or infiltration by pathogens, in contrast to orderly, programmed cell death via apoptosis. The discovery of necroptosis showed that cells can

ABCA3 (954 words) [view diff] exact match in snippet view article find links to article

development of resistance to xenobiotics and engulfment during programmed cell death. Mutations in ABCA3 are associated to cataract-microcornea syndrome

Cell fate determination (2,966 words) [view diff] exact match in snippet view article find links to article

include cell proliferation, differentiation, cellular movement and programmed cell death. Each cell in an embryo receives molecular signals from neighboring

PDCD7 (466 words) [view diff] exact match in snippet view article find links to article

Programmed cell death protein 7 is a protein that in humans is encoded by the PDCD7 gene. This gene encodes a protein with sequence similarity to a mouse

Pyrin domain (1,166 words) [view diff] exact match in snippet view article find links to article

Proteins containing a pyrin domain are frequently involved in programmed cell death processes, including pyroptosis and apoptosis. Proteins that possess

MAPK phosphatase (1,883 words) [view diff] exact match in snippet view article find links to article

homeostasis. This can involve gene regulation, cell proliferation, programmed cell death and stress responses. MAPK phosphatases are therefore important

Jerry Adams (592 words) [view diff] exact match in snippet view article find links to article

PhD student, David Vaux, made the connection between apoptosis (programmed cell death) and cancer, while studying the bcl-2 gene in follicular lymphoma

Bogdan Đuričić (162 words) [view diff] exact match in snippet view article find links to article

chief area of scientific research was in molecular mechanisms of programmed cell death and biochemistry of ischemia. In 1974, he graduated from the Belgrade

PTPN13 (1,227 words) [view diff] exact match in snippet view article find links to article

through the PDZ domains, which suggested its role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein

DNASE1L1 (1,675 words) [view diff] exact match in snippet view article find links to article

300-base pair pieces represents the final step in the execution of programmed cell death (apoptosis). Cells can then no longer perform cell division and

Ethidium homodimer assay (150 words) [view diff] exact match in snippet view article find links to article

dying cells, while TUNEL only stains cells that have undergone programmed cell death. Laing, J.; Gober, M.; Golembewski, E.; Thompson, S.; Gyure, K.;

SIVA1 (1,004 words) [view diff] exact match in snippet view article find links to article

gene encodes a protein with an important role in the apoptotic (programmed cell death) pathway induced by the CD27 antigen, a member of the tumor necrosis

Ced-9 (1,798 words) [view diff] exact match in snippet view article find links to article

a gene found in Caenorhabditis elegans that inhibits/represses programmed cell death (apoptosis). The gene was discovered while searching for mutations

Ced-9 (1,798 words) [view diff] exact match in snippet view article find links to article

a gene found in Caenorhabditis elegans that inhibits/represses programmed cell death (apoptosis). The gene was discovered while searching for mutations

Mitochondrial fission (1,386 words) [view diff] exact match in snippet view article find links to article

plays a role in the cellular stress response and in apoptosis (programmed cell death). The Drp1 protein, a member of the dynamin family of large GTPases

Receptor editing (283 words) [view diff] exact match in snippet view article find links to article

of self reactive immature B-cells, in order to rescue them from programmed cell death, called apoptosis. It is thought that 20-50% of all peripheral naive

Tetrahydrobiopterin (2,818 words) [view diff] no match in snippet view article find links to article

Tetrahydrobiopterin (BH4, THB), also known as sapropterin (INN), is a cofactor of the three aromatic amino acid hydroxylase enzymes, used in the metabolism

ADP/ATP translocase 2 (1,932 words) [view diff] exact match in snippet view article find links to article

mitochondrial death pathway and cardiac myocyte apoptosis signaling. Programmed cell death is a distinct genetic and biochemical pathway essential to metazoans

Cryoablation (2,484 words) [view diff] exact match in snippet view article find links to article

ischemia and cell death; and induction of apoptosis, the so-called programmed cell death cascade. The most common application of cryoablation is to ablate

Shigekazu Nagata (599 words) [view diff] exact match in snippet view article find links to article

biochemist, best known for research on apoptosis, the process of programmed cell death occurring in multi-cellular organisms. Nagata identified Interferon

TIA1 (1,285 words) [view diff] exact match in snippet view article find links to article

can bind the 5'TOP sequence of 5'TOP mRNAs. It is associated with programmed cell death (apoptosis) and regulates alternative splicing of the gene encoding

Stefanie Dimmeler (856 words) [view diff] exact match in snippet view article find links to article

Leibniz Prize of the German Research Foundation for her work on the programmed cell death of endothelial cells. Since 2008 she has led the Institute for Cardiovascular

Immunoglobulin V-set domain (371 words) [view diff] exact match in snippet view article find links to article

molecules (JAM); in tyrosine-protein kinase receptors; and in the programmed cell death protein 1 (PD1). Immunoglobulin V-set, subgroup InterPro: IPR003596

Rosalind and Morris Goodman Cancer Research Centre (158 words) [view diff] exact match in snippet view article find links to article

signalling • Metabolism and cancer • DNA damage and apoptosis (programmed cell death) As of 2014, they are made up of 26 full faculty members and 31

ZFY (929 words) [view diff] exact match in snippet view article find links to article

spermatogenesis, wrongful expression of either Zfy1 or Zfy2 results in programmed cell death, apoptosis, at the mid-pachytene checkpoint. In mice, Zfy genes

Reactive oxygen species (8,525 words) [view diff] exact match in snippet view article find links to article

either protect against singlet oxygen induced toxicity or initiate programmed cell death. Levels of jasmonate play a key role in the decision between cell

AKTIP (850 words) [view diff] exact match in snippet view article find links to article

these morphological abnormalities are caused by altered patterns of programmed cell death. The protein encoded by this gene is similar to the ubiquitin ligase

FAF1 (934 words) [view diff] exact match in snippet view article find links to article

of Fas ligand (TNFSF6) with the FAS antigen (TNFRSF6) mediates programmed cell death, also called apoptosis, in a number of organ systems. The protein

Checkpoint inhibitor (2,164 words) [view diff] exact match in snippet view article find links to article

the molecules CTLA4, PD-1, and PD-L1. PD-1 is the transmembrane programmed cell death 1 protein (also called PDCD1 and CD279), which interacts with PD-L1

Stanley J. Korsmeyer (1,365 words) [view diff] exact match in snippet view article find links to article

cancer-causing genes, providing the first example of how interfering with programmed cell death could lead to cancer development. Korsmeyer authored over 250 scientific

Polyamine (1,684 words) [view diff] exact match in snippet view article find links to article

hormone. In addition, they are directly involved in regulation of programmed cell death. Polyamines promote homologous recombination (HR)-mediated double-strand

Promyelocytic leukemia protein (4,053 words) [view diff] exact match in snippet view article find links to article

number of regulatory cellular functions, including involvement in programmed cell death, genome stability, antiviral effects and controlling cell division

Emad Alnemri (237 words) [view diff] case mismatch in snippet view article find links to article

his thesis was on "Molecular Mechanisms of Glucocorticoid-induced Programmed Cell Death in Lymphoid Tissues", under advisor Gerald Litwack. He has held

Focal adhesion targeting region (363 words) [view diff] exact match in snippet view article find links to article

FAK-related protein kinase PTK2B/FAK2/PYK2, and alpha-catenin, vinculin, Programmed cell death protein 10 (PDCD10)/Cerebral Cavernous Malformation protein 3 (CCM3)

ATC code L01 (932 words) [view diff] no match in snippet view article find links to article

ATC code L01 Antineoplastic agents is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes

Granzyme A (1,629 words) [view diff] exact match in snippet view article find links to article

residues. In CTL-targeted cells, it activates caspase-independent programmed cell death pathways that are unique and parallel to that of Granzyme B, although

Cell lineage (1,528 words) [view diff] exact match in snippet view article find links to article

neurons. This research also led to the initial observations of programmed cell death, or apoptosis. After mapping various sections of the C. elegans'

PLSCR3 (1,032 words) [view diff] exact match in snippet view article find links to article

membrane protein that is rich in proline and integral in apoptosis, or programmed cell death. The regulation of apoptosis is critical for both cell development

Cryptic self epitopes (156 words) [view diff] exact match in snippet view article find links to article

developing T-cell and signal those "self-reactive" T-cells to die via programmed cell death (apoptosis) and thereby deletion from the T cell repertoire, preventing

Junying Yuan (1,669 words) [view diff] exact match in snippet view article find links to article

behind programmed cell death in the nematode Caenorhabditis elegans. She identified the proteins ced-3 and ced-4 as drivers behind programmed cell death in

MtDNA control region (1,629 words) [view diff] exact match in snippet view article find links to article

metabolism, synthesizing hemoglobin and steroids, and regulating programmed cell death. Besides the production of ATP, there is a complex relationship

Volasertib (1,760 words) [view diff] exact match in snippet view article find links to article

programmed cell death, however, in normal cells inhibition of PLK1 only causes temporary, reversible G1 and G2 arrest without programmed cell death.

Caenorhabditis elegans (10,941 words) [view diff] exact match in snippet view article find links to article

a very popular model system for studying developmental biology. Programmed cell death (apoptosis) eliminates many additional cells (131 in the hermaphrodite

Sjögren's disease (9,425 words) [view diff] exact match in snippet view article find links to article

lymphomagenesis (origin of lymphoma). Dysregulation of apoptosis (programmed cell death) is believed to play a role in the pathogenesis of a variety of

ABT-737 (649 words) [view diff] exact match in snippet view article find links to article

family is most notable for their regulation of apoptosis, a form of programmed cell death, at the mitochondrion; Bcl-2 and Bcl-xL are anti-apoptotic proteins

DAPK1 (1,172 words) [view diff] exact match in snippet view article find links to article

protein kinase 1 is a positive mediator of gamma-interferon induced programmed cell death. DAPK1 encodes a structurally unique 160-kD calmodulin dependent

Arenobufagin (1,539 words) [view diff] exact match in snippet view article find links to article

a high Bax/Bcl-2 ratio, which is associated with apoptosis, or programmed cell death. Bax translocation from cytosol to mitochondria was also found to

Par stability determinant (547 words) [view diff] exact match in snippet view article find links to article

Franch T, Pedersen K, Mikkelsen ND (1997). "Antisense RNA-regulated programmed cell death". Annu. Rev. Genet. 31: 1–31. doi:10.1146/annurev.genet.31.1.1.

Identification of cell death (1,397 words) [view diff] exact match in snippet view article find links to article

and proteins and a loss of compartmentalization. Apoptosis, or programmed cell death, is generally characterized by distinct morphological characteristics

Mitosis (7,272 words) [view diff] exact match in snippet view article find links to article

errors during mitosis can induce mitotic catastrophe, apoptosis (programmed cell death) or cause mutations. Certain types of cancers can arise from such

Immunologic checkpoint (385 words) [view diff] exact match in snippet view article find links to article

CD152), which is an inhibitory receptor found on immune cells and programmed cell death 1 (CD279), which has an important role in down-regulating the immune

Chris J. Leaver (1,124 words) [view diff] exact match in snippet view article find links to article

from the mitochondria to the cytosol occurs during heat-induced programmed cell death in cucumber plants". FEBS Letters. 463 (1–2): 151–154. Bibcode:1999FEBSL

Calliphora vomitoria (3,213 words) [view diff] exact match in snippet view article find links to article

the fly, such as cell death. While it is commonly believed that programmed cell death and apoptosis are the same, they are not always so. At the beginning

Hok/sok system (1,446 words) [view diff] exact match in snippet view article find links to article

Hayes F (September 2003). "Toxins-antitoxins: plasmid maintenance, programmed cell death, and cell cycle arrest". Science. 301 (5639): 1496–9. Bibcode:2003Sci

Angiotensin II receptor type 2 (1,722 words) [view diff] exact match in snippet view article find links to article

mediated by the renin–angiotensin system. This receptor mediates programmed cell death (apoptosis). Consistent with its apoptotic function, angiotensin

Tropomyosin receptor kinase A (3,328 words) [view diff] exact match in snippet view article find links to article

differentiation, neural proliferation, nociceptor response, and avoidance of programmed cell death. The binding of NGF to TrkA leads to a ligand-induced dimerization

ADP/ATP translocase 4 (1,608 words) [view diff] exact match in snippet view article find links to article

mitochondrial death pathway and cardiac myocyte apoptosis signaling. Programmed cell death is a distinct genetic and biochemical pathway essential to metazoans

Cavernous hemangioma (3,649 words) [view diff] exact match in snippet view article find links to article

genes – K-Rev interaction trapped 1 (ССМ1), malcavernin (CCM2) and programmed cell death protein 10 (ССМ3) – have been identified as having mutations thought

Megagametogenesis (1,073 words) [view diff] exact match in snippet view article find links to article

cells are involved with nourishing the embryo, but often undergo programmed cell death before fertilization occurs. Cell plates form around the antipodal

Imatinib (6,714 words) [view diff] exact match in snippet view article find links to article

the Bcr-Abl tyrosine-kinase. This can slow growth or result in programmed cell death of certain types of cancer cells. Imatinib was approved for medical

Pd1 (58 words) [view diff] exact match in snippet view article find links to article

refer to: Prussian S 3 a 19th-century steam locomotive PD-1 the Programmed cell death protein 1 receptor This disambiguation page lists articles associated

Giardiasis (5,501 words) [view diff] exact match in snippet view article find links to article

changes to the microvillus, increased intestinal permeability, and programmed cell death of small intestinal epithelial cells. Both trophozoites and cysts

VDAC3 (2,560 words) [view diff] exact match in snippet view article find links to article

mitochondrial death pathway and cardiac myocyte apoptosis signaling. Programmed cell death is a distinct genetic and biochemical pathway essential to metazoans

Dap (487 words) [view diff] exact match in snippet view article find links to article

human gene that encodes death-associated proteins, which mediate programmed cell death Diamidophosphate, phosphorylating compound Diaminopimelic acid,

MAPK14 (5,270 words) [view diff] exact match in snippet view article find links to article

implicated in diverse cellular functions, from gene expression to programmed cell death through a network of signaling molecules and transcription factors

Ischemic cell death (866 words) [view diff] exact match in snippet view article find links to article

caused by a failure in ion transporter function. Apoptosis, or programmed cell death involves a series of cell shrinking processes, beginning with cell

VDAC2 (2,675 words) [view diff] exact match in snippet view article find links to article

mitochondrial death pathway and cardiac myocyte apoptosis signaling. Programmed cell death is a distinct genetic and biochemical pathway essential to metazoans

Lymphoproliferative disorders (776 words) [view diff] exact match in snippet view article find links to article

shown to play a central role in the physiological regulation of programmed cell death. Normally, stimulation of recently activated T cells by antigen

ZBP1 (2,535 words) [view diff] exact match in snippet view article find links to article

sensor of influenza virus triggering the NLRP3 inflammasome and programmed cell death pathways". Science Immunology. 1 (2). doi:10.1126/sciimmunol.aag2045

Mixed lineage kinase domain like pseudokinase (810 words) [view diff] exact match in snippet view article find links to article

critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (RIP3)

ACER3 (326 words) [view diff] exact match in snippet view article find links to article

population proliferation inflammatory response myelination regulation of programmed cell death ceramide catabolic process lipid metabolism sphingolipid metabolic

Solasonine (540 words) [view diff] exact match in snippet view article find links to article

Solasonine enhances anticancer potential by inducing apoptosis, or programmed cell death, through the regulation of key pathways, such as the mitochondrial

IAP (446 words) [view diff] exact match in snippet view article find links to article

Inhibitor of apoptosis, a protein family involved in the suppression of programmed cell death (apoptosis) Integrated automation platform Integrin Associated Protein

Smoker's face (662 words) [view diff] case mismatch in snippet view article find links to article

Depletion, Opening of Mitochondrial Permeability Transition, and Programmed Cell Death". Plant Physiology. 128 (4): 1271–1281. doi:10.1104/pp.010999. PMC 154255

Michael Travisano (983 words) [view diff] exact match in snippet view article find links to article

higher rates of programmed cell death, as is seen in the protective boundary of skin cells. In snowflake yeast, programmed cell death is an adaptation

ENDOG (2,404 words) [view diff] exact match in snippet view article find links to article

mitochondrial death pathway and cardiac myocyte apoptosis signaling. Programmed cell death is a distinct genetic and biochemical pathway essential to metazoans

Ced-12 (1,471 words) [view diff] exact match in snippet view article find links to article

apoptosis has been triggered in a cell. Apoptosis, also known as programmed cell death, activates during development as well as in situations where a cell

Bacterial effector protein (3,272 words) [view diff] exact match in snippet view article find links to article

host programmed cell death. Induction of cell death. In contrast to inhibition of apoptosis, several effectors appear to induce programmed cell death. For

Plant embryonic development (2,507 words) [view diff] exact match in snippet view article find links to article

continued growth of the cotyledons and axis elongation. In addition, programmed cell death must occur during this stage. This is carried out throughout the

Webbed toes (705 words) [view diff] exact match in snippet view article find links to article

webbed fingers and webbed toes. Syndactyly occurs when apoptosis or programmed cell death during gestation is absent or incomplete. Webbed toes occur most

Egg cell (1,483 words) [view diff] exact match in snippet view article find links to article

and organelles to the oocytes. This transfer is followed by the programmed cell death (apoptosis) of the nurse cells. During oogenesis, 15 nurse cells

HMGA (407 words) [view diff] exact match in snippet view article find links to article

formation of 6-O-methylguanine) this causes an increase in apoptosis (programmed cell death). However, cells with diminished activity for either proteins HMGA1

Jasmonate (2,887 words) [view diff] exact match in snippet view article find links to article

mitochondria membranes and compromise the cell by causing apoptosis, or programmed cell death. JAs' roles in these processes are suggestive of methods by which

Guanylate-binding protein (1,262 words) [view diff] exact match in snippet view article find links to article

pathogens and causing bacterial cell lysis, GBP1 can also cause host-programmed cell death. The GBP family of proteins is highly conserved among many different

EIF4G2 (1,118 words) [view diff] exact match in snippet view article find links to article

4G isolated as a putative modulator of gamma interferon-induced programmed cell death". Mol. Cell. Biol. 17 (3): 1615–25. doi:10.1128/mcb.17.3.1615. PMC 231887

Hugh McDevitt (624 words) [view diff] exact match in snippet view article find links to article

can trigger the onset of type-1 diabetes. "A normal process - programmed cell death - causes a normal response," McDevitt said. "But it does this in

PKM2 (4,865 words) [view diff] exact match in snippet view article find links to article

analogue, H2O2, or UV light has been linked with caspase-independent programmed cell death. PKM2 is expressed in most human tumors. Initially, a switch from

GSDMC (118 words) [view diff] exact match in snippet view article find links to article

microtubule organizing center cytosol plasma membrane membrane Biological process programmed cell death biological process pyroptosis Sources:Amigo / QuickGO

Deoxyribonuclease gamma (1,191 words) [view diff] exact match in snippet view article find links to article

process DNA catabolic process programmed cell death involved in cell development apoptotic process programmed cell death apoptotic DNA fragmentation DNA

NPHP3 (590 words) [view diff] exact match in snippet view article find links to article

class of P-loop NTPases including animal and plant regulators of programmed cell death: multiple, complex domain architectures, unusual phyletic patterns

Spermatogonium (1,476 words) [view diff] exact match in snippet view article find links to article

response, exposure of spermatogonia to doxorubicin can also induce programmed cell death (apoptosis). Transverse section of a tubule of the testis of a rat

Heme C (892 words) [view diff] exact match in snippet view article find links to article

cytoplasmic cytochrome c, which must still contain heme C, leads to programmed cell death. Cytochrome c can be measured in human serum and can be used as

Blocking antibody (718 words) [view diff] no match in snippet view article find links to article

function. Some new treatments hypothesize the blocking of PD-1, a programmed cell-death protein, which will result in longer-lived T-cells. The blocking

Gasdermin A (111 words) [view diff] exact match in snippet view article find links to article

perinuclear region of cytoplasm cytosol plasma membrane membrane Biological process programmed cell death apoptotic process pyroptosis Sources:Amigo / QuickGO

Spontaneous remission (1,041 words) [view diff] exact match in snippet view article find links to article

explains the occurrence of spontaneous regression." Apoptosis (programmed cell death) and angiogenesis (growth of new blood vessels) are sometimes discussed

Pib2 (1,007 words) [view diff] exact match in snippet view article find links to article

PMID 25735653. S2CID 11609431. van Doorn WG (October 2011). "Classes of programmed cell death in plants, compared to those in animals". Journal of Experimental

Cysteine protease (1,278 words) [view diff] exact match in snippet view article find links to article

other animals, they are responsible for senescence and apoptosis (programmed cell death), MHC class II immune responses, prohormone processing, and extracellular

Interleukin 1 beta (3,273 words) [view diff] no match in snippet view article find links to article

abortively infected, where the virus gets detected inside the cell and a programmed cell-death, known as pyroptosis, kills the infected cell. Pyroptosis is mediated

Anti-dsDNA antibodies (2,924 words) [view diff] exact match in snippet view article find links to article

extracellular DNA. Apoptosis is the highly organised process of programmed cell death in which the cell degrades the nuclear DNA and signals for phagocytosis

Efferocytosis (832 words) [view diff] exact match in snippet view article find links to article

ISBN 9780826430212. deCathelineau AM, Henson PM (2003). "The final step in programmed cell death: phagocytes carry apoptotic cells to the grave". Essays in Biochemistry

Undercard (album) (215 words) [view diff] case mismatch in snippet view article

"Cruiserweights" "Only Existing Footage" "Communicating Doors" "Programmed Cell Death" "How I Left the Ministry" "Some Other Way" "Ambivalent Landscape

Suspensor (386 words) [view diff] exact match in snippet view article find links to article

Peng; Sun, Meng-Xiang (2019-08-02). "Maternal control of suspensor programmed cell death via gibberellin signaling". Nature Communications. 10 (1). doi:10

Inflammasome (7,866 words) [view diff] exact match in snippet view article find links to article

resulting from this cleavage induces a pro-inflammatory form of programmed cell death distinct from apoptosis, referred to as pyroptosis, which is responsible

Systemic acquired resistance (906 words) [view diff] exact match in snippet view article find links to article

effector triggered immunity (ETI). ETI often results in a form of programmed cell death (PCD), called hypersensitive response (HR). Pathogens can then evolve

Caspase 2 (918 words) [view diff] exact match in snippet view article find links to article

ligand positive regulation of apoptotic process ectopic germ cell programmed cell death apoptotic signaling pathway neural retina development apoptotic

Corneal keratocyte (1,355 words) [view diff] exact match in snippet view article find links to article

process that attracts special attention. In a healthy cornea the programmed cell death is a rare occasion, but immediately after an injury to the uppermost

Ageing (11,510 words) [view diff] exact match in snippet view article find links to article

may cause ageing. Programmed ageing should not be confused with programmed cell death (apoptosis). Human beings and members of other species, especially

GSDMB (201 words) [view diff] exact match in snippet view article find links to article

cytoplasm cytosol plasma membrane membrane cellular component Biological process programmed cell death biological process pyroptosis Sources:Amigo / QuickGO

Death effector domain (2,410 words) [view diff] exact match in snippet view article find links to article

both life and death cell decisions. Apoptosis is a controlled and programmed cell death that confers advantages during an organism lifecycle. The extrinsic

TRPM7 (548 words) [view diff] exact match in snippet view article find links to article

magnesium ion homeostasis calcium-dependent cell-matrix adhesion programmed cell death phosphorylation actomyosin structure organization cation transport

MARK4 (852 words) [view diff] exact match in snippet view article find links to article

midbody Biological process phosphorylation positive regulation of programmed cell death nervous system development protein phosphorylation microtubule bundle

Canine coronavirus (1,061 words) [view diff] exact match in snippet view article find links to article

Intestinal disease may be related to virus-induced apoptosis (programmed cell death) of cells of the epithelial mucosa of the small intestine. Canine

Aspergillus nidulans (767 words) [view diff] exact match in snippet view article find links to article

caspase-like proteases were isolated from A. nidulans samples under which programmed cell death had been induced. Findings such as these play a key role in determining

Carcinogen (4,590 words) [view diff] exact match in snippet view article find links to article

in colon cells. Also 27 studies reported that bile acids cause programmed cell death (apoptosis). Increased apoptosis can result in selective survival

Bcl-2-like protein 1 (2,223 words) [view diff] case mismatch in snippet view article find links to article

INHIBITOR OF PROGRAMMED CELL DEATH, MINIMIZED AVERAGE STRUCTURE 1maz: X-RAY STRUCTURE OF BCL-XL, AN INHIBITOR OF PROGRAMMED CELL DEATH 1pq0: Crystal

2002 in science (1,529 words) [view diff] exact match in snippet view article find links to article

discoveries concerning genetic regulation of organ development and programmed cell death" Turing Award: Ron Rivest, Adi Shamir, and Leonard Adleman Wollaston

SOD2 (3,223 words) [view diff] exact match in snippet view article find links to article

mitochondrial death pathway and cardiac myocyte apoptosis signaling. Programmed cell death is a distinct genetic and biochemical pathway essential to metazoans

Α-Eleostearic acid (467 words) [view diff] exact match in snippet view article find links to article

conjugated linoleic acid. The compound has been found to induce programmed cell death of fat cells, and of HL60 leukemia cells in vitro at a concentration

POU4F2 (992 words) [view diff] exact match in snippet view article find links to article

regulation of transcription by RNA polymerase II positive regulation of programmed cell death negative regulation of cell differentiation positive regulation

Pathophysiology of HIV/AIDS (1,841 words) [view diff] exact match in snippet view article find links to article

inflammasomes and inducing pyroptosis, a highly inflammatory form of programmed cell death. These findings cast CD4 T-cell death during HIV infection in a

Chemotherapy (17,515 words) [view diff] exact match in snippet view article find links to article

to repair it, the DNA strands can break. This leads to a form of programmed cell death called apoptosis. Alkylating agents will work at any point in the

Proteasome (16,845 words) [view diff] exact match in snippet view article find links to article

have recently been shown to act as important metabolites for both programmed cell death and for immunity. Molecular glues that target BRD4 for degradation

Conidium (1,778 words) [view diff] exact match in snippet view article find links to article

immunity in the lung relies on targeting fungal apoptosis-like programmed cell death". Science. 357 (6355): 1037–1041. Bibcode:2017Sci...357.1037S. doi:10

ETS transcription factor family (1,058 words) [view diff] exact match in snippet view article find links to article

cell cycle control, cell migration, cell proliferation, apoptosis (programmed cell death) and angiogenesis. Multiple ETS factors have been found to be associated

PGAM5 (107 words) [view diff] exact match in snippet view article find links to article

membrane Biological process protein dephosphorylation necroptosis programmed cell death dephosphorylation positive regulation of GTPase activity macroautophagy

Antamanide (696 words) [view diff] exact match in snippet view article find links to article

to determine whether the antamanide also inhibits the apoptosis (programmed cell death) of human cervical carcinoma cells caused by the permeability transition

PPIF (1,594 words) [view diff] exact match in snippet view article find links to article

regulation of apoptotic process cellular response to calcium ion programmed cell death negative regulation of intrinsic apoptotic signaling pathway negative

Pioneer neuron (350 words) [view diff] no match in snippet view article find links to article

appropriate target. In many systems pioneer neurons are eliminated by programmed cell-death and are not present in the adult. Neural development Meyer G, Soria

Prolidase deficiency (1,233 words) [view diff] no match in snippet view article find links to article

proposed that the buildup of non-degraded dipeptides might induce programmed cell-death (apoptosis), whereafter the cell's contents would be expelled into

EVA1A (210 words) [view diff] exact match in snippet view article find links to article

Aliases EVA1A, FAM176A, TMEM166, eva-1 homolog A, regulator of programmed cell death External IDs MGI: 2385247; HomoloGene: 12969; GeneCards: EVA1A;

Growth factor (1,131 words) [view diff] exact match in snippet view article find links to article

are used as "death" signals; they cause target cells to undergo programmed cell death or apoptosis. The nerve growth factor (NGF) was first discovered

3,4-Dihydroxyphenylacetaldehyde (608 words) [view diff] exact match in snippet view article find links to article

mitochondria were highly potent in inducing a pathway associated with programmed cell death (or apoptosis), permeability transition. This suggests the cytotoxity

School of Medical Sciences, University of Manchester (1,136 words) [view diff] exact match in snippet view article find links to article

discoveries concerning 'genetic regulation of organ development and programmed cell death'. Raymond Tallis, gerontologist. Nesta Wells, first British female

School of Medical Sciences, University of Manchester (1,136 words) [view diff] exact match in snippet view article find links to article

discoveries concerning 'genetic regulation of organ development and programmed cell death'. Raymond Tallis, gerontologist. Nesta Wells, first British female

SPATA2 (423 words) [view diff] exact match in snippet view article find links to article

response regulation of necroptotic process protein K63-linked deubiquitination protein linear deubiquitination programmed cell death Sources:Amigo / QuickGO

Mebendazole (1,311 words) [view diff] exact match in snippet view article find links to article

which allows pro-apoptotic protein Bax to dimerize and initiate programmed cell death. Mebendazole is available as a generic medication. Mebendazole is

ING1 (1,538 words) [view diff] exact match in snippet view article find links to article

in the elimination of UV-damaged cells through the induction of programmed cell death (apoptosis). ING1 is located near the following genes on Chromosome

Procarbazine (821 words) [view diff] exact match in snippet view article find links to article

Proliferating cancer cells need to replicate their DNA and undergo programmed cell death (apoptosis) in response to DNA strand breaks. Normal or non-proliferating

Obligate parasite (2,103 words) [view diff] exact match in snippet view article find links to article

to reduce the replication and spread of pathogens is apoptosis (programmed cell death). Some obligate parasites have developed ways to suppress this phenomenon

Phycodnaviridae (9,384 words) [view diff] exact match in snippet view article find links to article

viral sphingolipids produced during the lytic stage are involved in programmed cell death in coccolithophore populations. A high correlation was found between

Ancrod (1,762 words) [view diff] exact match in snippet view article find links to article

that the substance has interesting apoptotic properties (causing programmed cell death), which remain to be explored. The half-life of ancrod is 3 to 5

Trichostatin A (690 words) [view diff] case mismatch in snippet view article find links to article

Clinical Significance in Cancer: HDAC Inhibitor-Induced Apoptosis". Programmed Cell Death in Cancer Progression and Therapy. Advances in Experimental Medicine

Peptidomimetic (1,365 words) [view diff] exact match in snippet view article find links to article

cells, an approach known as targeted chemotherapy, by inducing programmed cell death by a process called apoptosis. The following two examples mimic

Embryomics (2,179 words) [view diff] exact match in snippet view article find links to article

into mature adult somatic cell types, or which disappear due to programmed cell death (apoptosis). The entire process of embryogenesis can be described

Omigapil (2,218 words) [view diff] exact match in snippet view article find links to article

Kingdom at Great Ormond Street Hospital (UCL). Omigapil inhibits programmed cell death (apoptosis) through the enzymes glyceraldehyde 3-phosphate dehydrogenase

RIPK1 (4,951 words) [view diff] exact match in snippet view article find links to article

sensor of influenza virus triggering the NLRP3 inflammasome and programmed cell death pathways". Science Immunology. 1 (2) (published 2016-08-05). doi:10

Central nervous system cavernous hemangioma (2,090 words) [view diff] exact match in snippet view article find links to article

the most recently identified CCM gene . CCM3 is known as PDCD10 (programmed cell death 10), which was initially identified as a gene that is up-regulated

LARP6 (354 words) [view diff] exact match in snippet view article find links to article

novel member of the Lupus Antigen family, is induced during the programmed cell death of skeletal muscles in the moth Manduca sexta". Gene. 393 (1–2):

4-Hydroxyestrone (1,093 words) [view diff] exact match in snippet view article find links to article

cancer treatment. 4-OHE1 acts as a ferroptosis inhibitor, a form of programmed cell death associated with cancer cell survival. Specifically, 4-OHE1 inhibits

Ben Barres (3,409 words) [view diff] exact match in snippet view article find links to article

connections with their targets. These studies investigated how this programmed cell death, apoptosis, occurred in such a tremendous scale. Additionally, he

Chromosome 19 (2,547 words) [view diff] exact match in snippet view article find links to article

receptor PALM: encoding protein Paralemmin PDCD5: encoding protein Programmed cell death protein 5 PEX11G: peroxisomal biogenesis factor 11 gamma PGK1P2:

DAD1 (695 words) [view diff] exact match in snippet view article find links to article

cell death, was initially identified as a negative regulator of programmed cell death in the temperature sensitive tsBN7 cell line. The DAD1 protein disappeared

PHLDA1 (616 words) [view diff] case mismatch in snippet view article find links to article

"TDAG51 Is Induced by Homocysteine, Promotes Detachment-mediated Programmed Cell Death, and Contributes to the Development of Atherosclerosis in Hyperhomocysteinemia"

IFI16 (1,383 words) [view diff] exact match in snippet view article find links to article

helper CD4 T cells by pyroptosis, a highly inflammatory form of programmed cell death. Recently, it has been shown how IFI16, once extracellularly released

Nociceptor (2,811 words) [view diff] exact match in snippet view article find links to article

abdomen: origins, dendritic morphology, and segment- and age-dependent programmed cell death". Neural Development. 4 (1): 37. doi:10.1186/1749-8104-4-37. ISSN 1749-8104

Chromosome 3 (1,991 words) [view diff] exact match in snippet view article find links to article

PCCB: propionyl Coenzyme A carboxylase, beta polypeptide PDCD10: programmed cell death 10 PIK3CA: phosphoinositide-3-kinase, catalytic, alpha polypeptide

John Savill (830 words) [view diff] exact match in snippet view article find links to article

"Macrophage phagocytosis of aging neutrophils in inflammation. Programmed cell death in the neutrophil leads to its recognition by macrophages". Journal

Erythropoiesis (1,771 words) [view diff] exact match in snippet view article find links to article

Föller; Stephan M. Huber; Florian Lang (August 2008). "Erythrocyte programmed cell death". IUBMB Life. 60 (10): 661–668. doi:10.1002/iub.106. PMID 18720418

Zeta toxin protein domain (338 words) [view diff] exact match in snippet view article find links to article

, Shoeman, R.L. and Meinhart, A. (2011). "A novel mechanism of programmed cell death in bacteria by toxin-antitoxin systems corrupts peptidoglycan synthesis"

Actibind (1,363 words) [view diff] exact match in snippet view article find links to article

unwanted cells that have been damaged beyond repair; the process of programmed cell death. Apoptosis' dysregulation can trigger irregular responses that contribute

DNA damage-inducible transcript 3 (5,472 words) [view diff] exact match in snippet view article find links to article

PMC 4284148. PMID 24994655. Elmore S (June 2007). "Apoptosis: a review of programmed cell death". Toxicologic Pathology. 35 (4): 495–516. doi:10.1080/01926230701320337

HAVCR2 (2,940 words) [view diff] exact match in snippet view article find links to article

checkpoint and together with other inhibitory receptors including programmed cell death protein 1 (PD-1) and lymphocyte activation gene 3 protein (LAG3)

Integrin beta 5 (1,273 words) [view diff] exact match in snippet view article find links to article

Pasqualini Renata (May 2003). "Alpha v beta 5 integrin-dependent programmed cell death triggered by a peptide mimic of annexin V". Mol. Cell. 11 (5): 1151–62

Phytoalexin (1,771 words) [view diff] exact match in snippet view article find links to article

surrounding the site of infection are signaled to undergo apoptosis, or programmed cell death, in order to prevent the spread of the pathogen to the rest of the

Retinoic acid receptor gamma (1,208 words) [view diff] exact match in snippet view article find links to article

positive regulation of apoptotic process positive regulation of programmed cell death cellular response to leukemia inhibitory factor multicellular organism

Trichothecene (5,688 words) [view diff] exact match in snippet view article find links to article

which inevitably leads to oxidative stress and induction of the programmed cell death pathway, apoptosis. Additionally, trichothecenes such as T-2 have

APBB2 (655 words) [view diff] exact match in snippet view article find links to article

FE65-like protein 1 regulates both apoptotic and caspase-independent programmed cell death mediated by tumor necrosis factor". Biochem. Biophys. Res. Commun

Retinoic acid receptor beta (1,275 words) [view diff] exact match in snippet view article find links to article

organism growth embryonic eye morphogenesis positive regulation of programmed cell death negative regulation of apoptotic process negative regulation of

Carlo Gambacorti-Passerini (634 words) [view diff] exact match in snippet view article find links to article

revolutionary drug. Specifically, he showed that apoptosis, or programmed cell death, was the predominant mechanism through which imatinib eliminates

UDP-N-acetylglucosamine kinase (289 words) [view diff] exact match in snippet view article find links to article

Gebhardt M, Shoeman RL, Meinhart A (March 2011). "A novel mechanism of programmed cell death in bacteria by toxin-antitoxin systems corrupts peptidoglycan synthesis"

Heterophyes heterophyes (1,657 words) [view diff] exact match in snippet view article find links to article

NF-jB. Caspase-3 and NF-jB are protein that are essential to induce programmed cell death, apoptosis. Diagnosis done by stool examination is difficult when

Neuroborreliosis (2,154 words) [view diff] exact match in snippet view article find links to article

Yang, Yong; Jiang, Gening; Zhang, Peng; Fan, Jie (December 2015). "Programmed cell death and its role in inflammation". Military Medical Research. 2 (1):

Betulinic acid (1,916 words) [view diff] exact match in snippet view article find links to article

PMID 12118187. Tan Y, Yu R, Pezzuto JM (July 2003). "Betulinic acid-induced programmed cell death in human melanoma cells involves mitogen-activated protein kinase

Finger (2,886 words) [view diff] exact match in snippet view article find links to article

Garcia-Martinez, D. Macias et al: Internucleosomal DNA fragmentation and programmed cell death (apoptosis) in the interdigital tissue of the embryonic chick leg

RAB9A (881 words) [view diff] exact match in snippet view article find links to article

"A tomato homologue of the human protein PIRIN is induced during programmed cell death". Plant Mol. Biol. 46 (4): 459–68. doi:10.1023/A:1010618515051.

DNA fragmentation (1,498 words) [view diff] exact match in snippet view article find links to article

fragmentation is a natural fragmentation that cells perform in apoptosis (programmed cell death). DNA fragmentation is a biochemical hallmark of apoptosis. In dying

ANKRD25 (527 words) [view diff] exact match in snippet view article find links to article

of G1/S transition of mitotic cell cycle negative regulation of programmed cell death negative regulation of intracellular estrogen receptor signaling

Antimutagen (1,049 words) [view diff] exact match in snippet view article find links to article

nucleotide excision repair such as XPA and XPC; Selenium: Induces programmed cell death via many signalling pathways as well as protects the cells against

2002 in England (2,416 words) [view diff] exact match in snippet view article find links to article

discoveries concerning 'genetic regulation of organ development and programmed cell death'". Cherie Blair apologises for the embarrassment she caused in buying

Chemical modification (1,476 words) [view diff] exact match in snippet view article find links to article

important during cell signaling, removing misfolded proteins, and programmed cell death (apoptosis). In some cases, proteolysis can be used to regulate

Ubiquitin carboxy-terminal hydrolase L1 (2,637 words) [view diff] exact match in snippet view article find links to article

Uchl1 increases the susceptibility of pancreatic beta-cells to programmed cell death, indicating that this protein plays a protective role in neuroendocrine

PAX2 (1,868 words) [view diff] exact match in snippet view article find links to article

system development cell fate determination negative regulation of programmed cell death vestibulocochlear nerve formation camera-type eye development metanephric

Phosphatidylserine (1,989 words) [view diff] exact match in snippet view article find links to article

cognitive decline. PS plays a crucial role in the process of apoptosis (programmed cell death). During apoptosis, PS translocates from the inner leaflet of the

Annexin A5 affinity assay (853 words) [view diff] exact match in snippet view article find links to article

only on the inner leaflet of the membrane. Apoptosis is a form of programmed cell death that is used by the body to remove unwanted, damaged, or senescent

Geoffrey M. Cooper (644 words) [view diff] exact match in snippet view article find links to article

Erhardt, P., Schremser, E.J., and Cooper, G.M. 1999. B-Raf inhibits programmed cell death downstream of cytochrome c release from mitochondria by activating

Osteocyte (2,565 words) [view diff] exact match in snippet view article find links to article

a consequence of senescence, degeneration/necrosis, apoptosis (programmed cell death), and/or osteoclastic engulfment. The percentage of dead osteocytes

Neurotoxicity (2,286 words) [view diff] exact match in snippet view article find links to article

3,4-Dihydroxyphenylacetaldehyde (DOPAL), is a potent inducer of programmed cell death (apoptosis) in dopaminergic neurons. DOPAL may play an important

T helper cell (6,618 words) [view diff] exact match in snippet view article find links to article

inflammasomes, thus causing pyroptosis (a highly inflammatory form of programmed cell death). At this point chronic inflammation ensues, and functional CD4+

Dz13 (1,060 words) [view diff] case mismatch in snippet view article find links to article

Cytotoxicity in Endothelial Cells with Features of Nonapoptotic Programmed Cell Death. Oligonucleotides 18(3), 257-268. Fahmy, R. et al (2006) Suppression

Anal cancer (3,017 words) [view diff] exact match in snippet view article find links to article

speculate that smoking interferes with a process called apoptosis, or programmed cell death, which helps rid the body of abnormal cells that could turn cancerous

PANoptosis (4,030 words) [view diff] exact match in snippet view article find links to article

sensor of influenza virus triggering the NLRP3 inflammasome and programmed cell death pathways". Science Immunology. 1 (2): aag2045. doi:10.1126/sciimmunol

Breast cancer (15,802 words) [view diff] exact match in snippet view article find links to article

and to die at the proper time. Normal cells will self-destruct (programmed cell death) when they are no longer needed. Until then, cells are protected

Death-associated protein 6 (1,528 words) [view diff] exact match in snippet view article find links to article

death. It is also essential for development of nerval system by programmed cell death. The real apoptotic process starts after activating this pathway

PLCG2 (1,405 words) [view diff] exact match in snippet view article find links to article

phosphatidylinositol biosynthetic process negative regulation of programmed cell death B cell differentiation T cell receptor signaling pathway activation

Lina M. Obeid (858 words) [view diff] case mismatch in snippet view article find links to article

Linardic, Corinne M.; Karolak, Linda A.; Hannun, Yusuf A. (1993). "Programmed Cell Death Induced by Ceramide". Science. 259 (5102): 1769–1771. Bibcode:1993Sci

FGF4 (1,874 words) [view diff] exact match in snippet view article find links to article

forelimbs and hindlimbs. It also regulates limb digit number and programmed cell death in the interdigital mesenchyme. Altered levels or regulation of

Death-associated protein 6 (1,528 words) [view diff] exact match in snippet view article find links to article

death. It is also essential for development of nerval system by programmed cell death. The real apoptotic process starts after activating this pathway

Lipid signaling (5,633 words) [view diff] exact match in snippet view article find links to article

mediates many cell-stress responses, including the regulation of programmed cell death (apoptosis) and cell aging (senescence). Numerous research works

Addiction module (701 words) [view diff] exact match in snippet view article find links to article

Engelberg-Kulka, Hanna; Gad Glaser (October 1999). "Addiction modules and programmed cell death and antideath in bacterial cultures". Annual Review of Microbiology

6-Diazo-5-oxo-L-norleucine (990 words) [view diff] exact match in snippet view article find links to article

could be shown in vitro that DON treatment led to apoptosis, or programmed cell death. Different pathways were investigated; it could be shown that the

POU4F1 (2,159 words) [view diff] exact match in snippet view article find links to article

regulation of transcription by RNA polymerase II negative regulation of programmed cell death positive regulation of osteoclast differentiation regulation of

Christopher E. Rudd (890 words) [view diff] exact match in snippet view article find links to article

synthase kinase-3 (GSK-3) to down-regulate the inhibitory co-receptor programmed cell death-1 (PD-1) in cancer immunotherapy. Rudd's work has had important

Animal testing on invertebrates (899 words) [view diff] exact match in snippet view article find links to article

programmed to die during development, leading to the discovery that programmed cell death is an active process under genetic control. The simple nervous system

Josef Victor Rohon (408 words) [view diff] exact match in snippet view article find links to article

2004). "Slow degeneration of zebrafish Rohon-Beard neurons during programmed cell death". Developmental Dynamics. 229 (1): 30–41. doi:10.1002/dvdy.10488

Rakesh Bhatnagar (353 words) [view diff] case mismatch in snippet view article find links to article

Biology of Infectious Diseases, Recombinant Vaccine Development, and Programmed Cell Death in Prokaryotes. Kumar, Mamidala Jagadesh (1 August 2016). "Prof

DFNA5 (922 words) [view diff] exact match in snippet view article find links to article

signaling pathway negative regulation of cell population proliferation programmed cell death cell death positive regulation of MAPK cascade necrotic cell death

Biological life cycle (2,972 words) [view diff] exact match in snippet view article find links to article

cell damage, terminal differentiation as occurs in nerve cells, or programmed cell death (apoptosis) during development. Maintenance of cell division potential

Taurolidine (2,201 words) [view diff] exact match in snippet view article find links to article

Brock M, Möhler H (2003-06-01). "Enhancement of Fas-ligand-mediated programmed cell death by taurolidine". Anticancer Research. 23 (3B): 2309–14. PMID 12894508

Nucleoside-modified messenger RNA (2,503 words) [view diff] exact match in snippet view article find links to article

interferon and TNF-alpha, and when sufficiently intense lead to programmed cell death. The inflammatory nature of exogenous RNA can be masked by modifying

DCPS (gene) (1,046 words) [view diff] exact match in snippet view article

process mRNA cis splicing, via spliceosome negative regulation of programmed cell death mRNA processing nuclear-transcribed mRNA catabolic process,

Antinuclear antibody (6,260 words) [view diff] exact match in snippet view article find links to article

lymphocytes that recognise human proteins (autoantigens) either undergo programmed cell death (apoptosis) or become non-functional. This self-tolerance means

AV-HALT (793 words) [view diff] exact match in snippet view article find links to article

Capron, A (1991). "Cell dysfunction and depletion in AIDS: The programmed cell death hypothesis". Immunology Today. 12 (4): 102–5. doi:10.1016/0167-5699(91)90092-8

Michael Karin (674 words) [view diff] exact match in snippet view article find links to article

immunity. Having found that IKK dependent NF-κB activation suppresses programmed cell death, Karin and colleagues postulated that NF-κB provided the long suspected

Serine/threonine-specific protein kinase (1,210 words) [view diff] exact match in snippet view article find links to article

Serine/threonine kinases play a role in the regulation of cell proliferation, programmed cell death (apoptosis), cell differentiation, and embryonic development.[citation

DLC1 (3,165 words) [view diff] exact match in snippet view article find links to article

phosphorylation is as yet unknown. DLC1 is responsible for inducing programmed cell death by at least two mechanisms: caspase-3-mediated apoptosis and Bcl-2

Ciliary neurotrophic factor (1,748 words) [view diff] exact match in snippet view article find links to article

organ morphogenesis neuron development regulation of retinal cell programmed cell death nervous system development ciliary neurotrophic factor-mediated

T cell (9,237 words) [view diff] exact match in snippet view article find links to article

exhausted the cells that present the same molecular markers (typically, programmed cell death protein 1 [PD-1])." Indeed, it is now starting to emerge that exhaustion

BAG1 (1,637 words) [view diff] exact match in snippet view article find links to article

protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred

Bortezomib (2,272 words) [view diff] exact match in snippet view article find links to article

prevent degradation of pro-apoptotic factors, thereby triggering programmed cell death in neoplastic cells. Bortezomib causes a rapid and dramatic change

Nuclear bodies (1,890 words) [view diff] exact match in snippet view article find links to article

it is targeted to dots. whereas overexpression of PML results in programmed cell death. One hypothesized function of the dots is as a 'nuclear dump' or

Fox Chase Cancer Center (2,130 words) [view diff] exact match in snippet view article find links to article

and AKT2 genes - the first viral oncogenes described that inhibit programmed cell death. 1991 Timothy Yen discovers that a molecular motor controls the

Chromosome 15 (3,031 words) [view diff] exact match in snippet view article find links to article

albinism II (pink-eye dilution homolog, mouse) PDCD7: encoding protein Programmed cell death protein 7 PIF1: encoding protein PIF1 5'-to-3' DNA helicase PIGBOS1:

Lung cancer (9,783 words) [view diff] exact match in snippet view article find links to article

affect the cell's normal functions, including cell proliferation, programmed cell death (apoptosis), and DNA repair. Eventually, cells gain enough genetic

XPB (2,065 words) [view diff] exact match in snippet view article find links to article

oxidative stress. XPB helicase is also a component of the p53-mediated programmed cell death (apoptosis) pathway. Mutations in XPB and other related complementation

Th 9 cell (3,209 words) [view diff] exact match in snippet view article find links to article

fully substitute the role of TGF-β in TH9 cells, then Jagged2, programmed cell death ligand (PD-L2), cyclooxy- genase (COX)-2, 1,25-dihydroxyvitamin

N. Louise Glass (666 words) [view diff] exact match in snippet view article find links to article

and molecular analyses of mating type, nonself recognition and programmed cell death in filamentous fungi. In 1999 she was recruited to the Plant and

Tumor suppressor gene (3,415 words) [view diff] exact match in snippet view article find links to article

induce apoptosis. If damage cannot be repaired, the cell initiates programmed cell death to remove the threat it poses to the organism as a whole. (e.g.

DNAJA3 (1,956 words) [view diff] exact match in snippet view article find links to article

positive regulation of apoptotic process negative regulation of programmed cell death regulation of catalytic activity negative regulation of NF-kappaB

MAGED1 (1,248 words) [view diff] exact match in snippet view article find links to article

demonstrated to be involved in the p75 neurotrophin receptor mediated programmed cell death pathway. Three transcript variants encoding two different isoforms

MicroRNA 425 (546 words) [view diff] case mismatch in snippet view article find links to article

regulates chemoresistance in colorectal cancer cells via regulation of Programmed Cell Death 10". J. Cell. Mol. Med. 20 (2): 360–9. doi:10.1111/jcmm.12742. PMC 4727563

Anteater (4,548 words) [view diff] exact match in snippet view article find links to article

adaptations that lead to very low rates of cancer among them, such as programmed cell death at very low levels of DNA damage. The silky anteater and both of

EIF4A1 (2,589 words) [view diff] exact match in snippet view article find links to article

3109/10409238.2014.887051. PMID 24520918. S2CID 207506515. "PDCD4 programmed cell death 4 [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Ali

Genotoxicity (3,530 words) [view diff] exact match in snippet view article find links to article

2007). "Helicobacter pylori infection induces oxidative stress and programmed cell death in human gastric epithelial cells". Infect Immun. 75 (8): 4030–9

John Angus Hickman (947 words) [view diff] exact match in snippet view article find links to article

"Drug-target interactions: only the first step in the commitment to a programmed cell death?". Br. J. Cancer. 64 (1): 192–196. doi:10.1038/bjc.1991.269. PMC 1977304

The Extra Lens (360 words) [view diff] case mismatch in snippet view article find links to article

"Cruiserweights", "Only Existing Footage", "Communicating Doors", "Programmed Cell Death", "How I Left the Ministry", "Some Other Way", "Ambivalent Landscape

Insulator (genetics) (2,065 words) [view diff] exact match in snippet view article

processes that are important for cell growth, cell differentiation, and programmed cell death (apoptosis). Two of these cell cycle regulation genes that are known

Adrenopause (615 words) [view diff] exact match in snippet view article find links to article

attributed to several factors: Apoptosis of Adrenal Cells: Age-related programmed cell death in the adrenal cortex reduces the number of androgen-secreting cells

STK24 (1,383 words) [view diff] exact match in snippet view article find links to article

regulation of multiple functions of the cells and interaction with programmed cell death 10 (CCM3). CCM is a pathological vascular situation that, influencing

TMBIM4 (1,028 words) [view diff] exact match in snippet view article find links to article

protein present in the Golgi that helps regulate apoptosis, a form of programmed cell death. By regulating the fluxes of Ca+2, an increase of GAAP can help

Cell cycle withdrawal (2,198 words) [view diff] exact match in snippet view article find links to article

cells to stop their functions and differentiations to undergo a programmed cell death process called apoptosis. Furthermore, the withdrawal process could

Anti-neutrophil cytoplasmic antibody (2,273 words) [view diff] exact match in snippet view article find links to article

hypersensitivity reaction.[citation needed] Neutrophil apoptosis, or programmed cell death, is vital in controlling the duration of the early inflammatory

Uncombable hair syndrome (2,429 words) [view diff] exact match in snippet view article find links to article

induces cell proliferation, migration, and invasion, and promotes programmed cell death. This came to show that transglutaminase 3 will be a candidate growth

Lysosome (4,211 words) [view diff] exact match in snippet view article find links to article

Additionally, lysosomal enzymes can trigger lysosomal-mediated programmed cell death (LM-PCD) if released into the cytoplasm. To maintain their acidic

Paraplegin (1,256 words) [view diff] exact match in snippet view article find links to article

permeability mitochondrial outer membrane permeabilization involved in programmed cell death mitochondrion organization anterograde axonal transport Sources:Amigo

Ureteral cancer (1,708 words) [view diff] exact match in snippet view article find links to article

undergo a DNA mutation resulting in abnormal growth of cells without programmed cell death; this eventually leads to blockage of the ureter and possibly other

Hepatocyte growth factor (2,623 words) [view diff] exact match in snippet view article find links to article

apoptotic process negative regulation of hydrogen peroxide-mediated programmed cell death positive regulation of neuron projection regeneration positive regulation

Nuclear pore glycoprotein p62 (2,260 words) [view diff] exact match in snippet view article find links to article

kinase/NF-kappaB signaling protein transport negative regulation of programmed cell death nuclear transport viral process positive regulation of epidermal

Aortic aneurysm (3,938 words) [view diff] exact match in snippet view article find links to article

short, raising HDL cholesterol is beneficial because it induces programmed cell death. The walls of a failing aorta are replaced and strengthened. New

Myristoylation (2,566 words) [view diff] exact match in snippet view article find links to article

its receptor. Myristoylation is an integral part of apoptosis, or programmed cell death. Apoptosis is necessary for cell homeostasis and occurs when cells

Eileen White (489 words) [view diff] exact match in snippet view article find links to article

that encodes Bcl-2, a mammalian protein that inhibits apoptosis, programmed cell death. She then joined Rutgers University as an assistant professor in

Lipid-anchored protein (2,151 words) [view diff] exact match in snippet view article find links to article

which the myristoylation of a protein is important is in apoptosis, programmed cell death. After the protein BH3 interacting-domain death agonist (Bid) has

WFS1 (1,173 words) [view diff] exact match in snippet view article find links to article

ubiquitin-dependent ERAD pathway renal water homeostasis negative regulation of programmed cell death positive regulation of protein ubiquitination negative regulation

Germ cell (4,040 words) [view diff] exact match in snippet view article find links to article

is also ensured by a balance between germ cell development and programmed cell death. Identification of «death triggering signals» and corresponding