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Longer titles found: Programmed cell death protein 1 (view)

searching for Programmed cell death 268 found (922 total)

alternate case: programmed cell death

Inhibitor of apoptosis (1,521 words) [view diff] exact match in snippet view article find links to article

of proteins that mainly act on the intrinsic pathway that block programmed cell death, which can frequently lead to cancer or other effects for the cell
Protein serine/threonine phosphatase (215 words) [view diff] exact match in snippet view article find links to article
regulates many cellular pathways involved in cell proliferation, programmed cell death (apoptosis), embryonic development, and cell differentiation. There
H. Robert Horvitz (1,925 words) [view diff] exact match in snippet view article find links to article
discoveries concerning the genetic regulation of organ development and programmed cell death" were "important for medical research and have shed new light on
Mitotic catastrophe (504 words) [view diff] exact match in snippet view article find links to article
chemical or physical stresses. Mitotic catastrophe is unrelated to programmed cell death or apoptosis and is observed in cells lacking functional apoptotic
PDCD4 (1,022 words) [view diff] exact match in snippet view article find links to article
Programmed cell death protein 4 is a protein that in humans is encoded by the PDCD4 gene. It is one of the targets of an oncomiR, MIRN21. This gene encodes
Bcl-2 family (2,011 words) [view diff] exact match in snippet view article find links to article
family is most notable for their regulation of apoptosis, a form of programmed cell death, at the mitochondrion. The Bcl-2 family proteins consists of members
Durvalumab (1,132 words) [view diff] exact match in snippet view article find links to article
kappa (IgG1κ) monoclonal antibody that blocks the interaction of programmed cell death ligand 1 (PD-L1) with the PD-1 (CD279). Durvalumab is known as a
Bcl-xL (861 words) [view diff] exact match in snippet view article find links to article
cytochrome c, which leads to caspase activation and ultimately, programmed cell death. It is a well-established concept in the field of apoptosis that
PDCD2 (959 words) [view diff] exact match in snippet view article find links to article
Programmed cell death protein 2 is a protein that in humans is encoded by the PDCD2 gene. This gene encodes a nuclear protein expressed in a variety of
Elesclomol (650 words) [view diff] exact match in snippet view article find links to article
Elesclomol (INN, codenamed STA-4783) is a drug that triggers apoptosis (programmed cell death) in cancer cells. It is being developed by Synta Pharmaceuticals
PDCD5 (742 words) [view diff] exact match in snippet view article find links to article
Programmed cell death protein 5 is a protein that in humans is encoded by the PDCD5 gene. This gene encodes a protein expressed in tumor cells during
PDCD10 (1,652 words) [view diff] exact match in snippet view article find links to article
Programmed cell death protein 10 is a protein that in humans is encoded by the PDCD10 gene. This gene encodes a protein, originally identified in a premyeloid
Nuclease S1 (828 words) [view diff] exact match in snippet view article find links to article
prokaryotes and eukaryotes and are thought to be associated in programmed cell death and also in tissue differentiation. Furthermore, they are secreted
PDCD6IP (1,242 words) [view diff] exact match in snippet view article find links to article
Programmed cell death 6-interacting protein also known as ALIX is a protein that in humans is encoded by the PDCD6IP gene. This gene encodes a protein
PDCD6 (1,225 words) [view diff] exact match in snippet view article find links to article
Programmed cell death protein 6 is a protein that in humans is encoded by the PDCD6 gene. This gene encodes a calcium-binding protein belonging to the
CAMK (884 words) [view diff] exact match in snippet view article find links to article
responding genes. CAMK also works to regulate the cell life cycle (i.e. programmed cell death), rearrangement of the cell's cytoskeletal network, and mechanisms
TNF receptor superfamily (496 words) [view diff] exact match in snippet view article find links to article
the fact that they seemed to play an important role in apoptosis (programmed cell death), although they are now known to play other roles as well. In the
PDCD7 (463 words) [view diff] exact match in snippet view article find links to article
Programmed cell death protein 7 is a protein that in humans is encoded by the PDCD7 gene. This gene encodes a protein with sequence similarity to a mouse
ABCA3 (950 words) [view diff] exact match in snippet view article find links to article
development of resistance to xenobiotics and engulfment during programmed cell death. Mutations in ABCA3 are associated to cataract-microcornea syndrome
Necroptosis (1,568 words) [view diff] exact match in snippet view article find links to article
cellular damage or infiltration by pathogens, in contrast to orderly, programmed cell death via apoptosis. The discovery of necroptosis showed that cells can
PTPN13 (1,142 words) [view diff] exact match in snippet view article find links to article
through the PDZ domains, which suggested its role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein
Tetrahydrobiopterin (2,481 words) [view diff] no match in snippet view article find links to article
Tetrahydrobiopterin (BH4, THB), also known as sapropterin (INN), is a cofactor of the three aromatic amino acid hydroxylase enzymes, used in the degradation
SIVA1 (990 words) [view diff] exact match in snippet view article find links to article
gene encodes a protein with an important role in the apoptotic (programmed cell death) pathway induced by the CD27 antigen, a member of the tumor necrosis
Cell fate determination (2,679 words) [view diff] exact match in snippet view article find links to article
include cell proliferation, differentiation, cellular movement and programmed cell death. Each cell in an embryo receives molecular signals from neighboring
MAPK phosphatase (1,868 words) [view diff] exact match in snippet view article find links to article
homeostasis. This can involve gene regulation, cell proliferation, programmed cell death and stress responses. MAPK phosphatases are therefore important
Ethidium homodimer assay (150 words) [view diff] exact match in snippet view article find links to article
dying cells, while TUNEL only stains cells that have undergone programmed cell death. Laing, J.; Gober, M.; Golembewski, E.; Thompson, S.; Gyure, K.;
Bogdan Đuričić (162 words) [view diff] exact match in snippet view article find links to article
chief area of scientific research was in molecular mechanisms of programmed cell death and biochemistry of ischemia. In 1974, he graduated from the Belgrade
Ced-9 (1,780 words) [view diff] exact match in snippet view article find links to article
a gene found in Caenorhabditis elegans that inhibits/represses programmed cell death (apoptosis). The gene was discovered while searching for mutations
Jerry Adams (534 words) [view diff] exact match in snippet view article find links to article
PhD student, David Vaux, made the connection between apoptosis (programmed cell death) and cancer, while studying the bcl-2 gene in follicular lymphoma
Receptor editing (280 words) [view diff] exact match in snippet view article find links to article
of self reactive immature B-cells, in order to rescue them from programmed cell death, called apoptosis. It is thought that 20-50% of all peripheral naive
Mitochondrial outer membrane permeabilization (304 words) [view diff] exact match in snippet view article find links to article
mitochondrial outer membrane permeability, is one of two ways apoptosis (programmed cell death) can be activated. It is part of the intrinsic pathway of apoptosis
Cryoablation (2,458 words) [view diff] exact match in snippet view article find links to article
ischemia and cell death; and induction of apoptosis, the so-called programmed cell death cascade. The most common application of cryoablation is to ablate
ADP/ATP translocase 2 (1,932 words) [view diff] exact match in snippet view article find links to article
mitochondrial death pathway and cardiac myocyte apoptosis signaling. Programmed cell death is a distinct genetic and biochemical pathway essential to metazoans
Checkpoint inhibitor (1,658 words) [view diff] exact match in snippet view article find links to article
the molecules CTLA4, PD-1, and PD-L1. PD-1 is the transmembrane programmed cell death 1 protein (also called PDCD1 and CD279), which interacts with PD-L1
Rosalind and Morris Goodman Cancer Research Centre (158 words) [view diff] exact match in snippet view article find links to article
signalling • Metabolism and cancer • DNA damage and apoptosis (programmed cell death) As of 2014, they are made up of 26 full faculty members and 31
Polyamine (1,366 words) [view diff] exact match in snippet view article find links to article
hormone. In addition, they are directly involved in regulation of programmed cell death. Polyamines promote homologous recombination (HR)-mediated double-strand
TIA1 (1,263 words) [view diff] exact match in snippet view article find links to article
can bind the 5'TOP sequence of 5'TOP mRNAs. It is associated with programmed cell death (apoptosis) and regulates alternative splicing of the gene encoding
AKTIP (850 words) [view diff] exact match in snippet view article find links to article
these morphological abnormalities are caused by altered patterns of programmed cell death. The protein encoded by this gene is similar to the ubiquitin ligase
FAF1 (927 words) [view diff] exact match in snippet view article find links to article
of Fas ligand (TNFSF6) with the FAS antigen (TNFRSF6) mediates programmed cell death, also called apoptosis, in a number of organ systems. The protein
Stefanie Dimmeler (941 words) [view diff] exact match in snippet view article find links to article
Leibniz Prize of the German Research Foundation for her work on the programmed cell death of endothelial cells. Since 2008 she has led the Institute for Cardiovascular
ZFY (936 words) [view diff] exact match in snippet view article find links to article
spermatogenesis, wrongful expression of either Zfy1 or Zfy2 results in programmed cell death, apoptosis, at the mid-pachytene checkpoint. In mice, Zfy genes
Shigekazu Nagata (584 words) [view diff] exact match in snippet view article find links to article
biochemist, best known for research on apoptosis, the process of programmed cell death occurring in multi-cellular organisms. Nagata identified Interferon
Immunoglobulin V-set domain (367 words) [view diff] exact match in snippet view article find links to article
molecules (JAM); in tyrosine-protein kinase receptors; and in the programmed cell death protein 1 (PD1). Immunoglobulin V-set, subgroup InterPro: IPR003596
Reactive oxygen species (8,445 words) [view diff] exact match in snippet view article find links to article
damage is present in mitochondria, a cell undergoes apoptosis or programmed cell death. In addition, ROS are produced in immune cell signaling via the
PD-1 and PD-L1 inhibitors (2,496 words) [view diff] exact match in snippet view article find links to article
association of the programmed death-ligand 1 (PD-L1) with its receptor, programmed cell death protein 1 (PD-1). The interaction of these cell surface proteins
Focal adhesion targeting region (363 words) [view diff] exact match in snippet view article find links to article
FAK-related protein kinase PTK2B/FAK2/PYK2, and alpha-catenin, vinculin, Programmed cell death protein 10 (PDCD10)/Cerebral Cavernous Malformation protein 3 (CCM3)
Promyelocytic leukemia protein (4,041 words) [view diff] exact match in snippet view article find links to article
number of regulatory cellular functions, including involvement in programmed cell death, genome stability, antiviral effects and controlling cell division
Cell lineage (1,480 words) [view diff] exact match in snippet view article find links to article
differentiation pathways). This research led to the initial observations of programmed cell death, or apoptosis. After mapping various sections of the C. elegans'
Stanley J. Korsmeyer (327 words) [view diff] exact match in snippet view article find links to article
apoptosis, Korsmeyer helped develop the concepts of the role of programmed cell death in carcinogenesis. In 1989 Korsmeyer was among the first to confirm
Carlo Gambacorti-Passerini (557 words) [view diff] exact match in snippet view article find links to article
revolutionary drug. Specifically, he showed that apoptosis, or programmed cell death, was the predominant mechanism through which imatinib eliminates
Cryptic self epitopes (156 words) [view diff] exact match in snippet view article find links to article
developing T-cell and signal those "self-reactive" T-cells to die via programmed cell death (apoptosis) and thereby deletion from the T cell repertoire, preventing
Emad Alnemri (237 words) [view diff] case mismatch in snippet view article find links to article
his thesis was on "Molecular Mechanisms of Glucocorticoid-induced Programmed Cell Death in Lymphoid Tissues", under advisor Gerald Litwack. He has held
13-Methyltetradecanoic acid (1,071 words) [view diff] exact match in snippet view article find links to article
13-Methyltetradecanoic acid (13-MTD) is a fatty acid known to induce apoptosis or “programmed cell death” of certain human cancer cells. 13-MTD was originally purified from
PLSCR3 (1,028 words) [view diff] exact match in snippet view article find links to article
membrane protein that is rich in proline and integral in apoptosis, or programmed cell death. The regulation of apoptosis is critical for both cell development
Sjögren syndrome (7,596 words) [view diff] exact match in snippet view article find links to article
lymphomagenesis (origin of lymphoma). Dysregulation of apoptosis (programmed cell death) is believed to play a role in the pathogenesis of a variety of
Volasertib (1,673 words) [view diff] exact match in snippet view article find links to article
programmed cell death, however, in normal cells inhibition of PLK1 only causes temporary, reversible G1 and G2 arrest without programmed cell death.
Junying Yuan (1,607 words) [view diff] exact match in snippet view article find links to article
behind programmed cell death in the nematode Caenorhabditis elegans. She identified the proteins ced-3 and ced-4 as drivers behind programmed cell death in
Spermatogonium (279 words) [view diff] exact match in snippet view article find links to article
response, exposure of spermatogonia to doxorubicin can also induce programmed cell death (apoptosis). Transverse section of a tubule of the testis of a rat
Cavernous hemangioma (2,991 words) [view diff] exact match in snippet view article find links to article
genes – K-Rev interaction trapped 1 (ССМ1), Malcavernin (CCM2) and Programmed cell death protein 10 (ССМ3) – have been identified as having mutations thought
DAPK1 (1,168 words) [view diff] exact match in snippet view article find links to article
protein kinase 1 is a positive mediator of gamma-interferon induced programmed cell death. DAPK1 encodes a structurally unique 160-kD calmodulin dependent
Par stability determinant (547 words) [view diff] exact match in snippet view article find links to article
Franch T, Pedersen K, Mikkelsen ND (1997). "Antisense RNA-regulated programmed cell death". Annu. Rev. Genet. 31: 1–31. doi:10.1146/annurev.genet.31.1.1.
HU-308 (3,880 words) [view diff] exact match in snippet view article find links to article
attenuating oxidative stress, inflammatory response, and apoptosis (programmed cell death). HU-308 is also classified as a non-steroidal anti-inflammatory
ABT-737 (671 words) [view diff] exact match in snippet view article find links to article
family is most notable for their regulation of apoptosis, a form of programmed cell death, at the mitochondrion; Bcl-2 and Bcl-xL are anti-apoptotic proteins
Inflammasome (5,942 words) [view diff] exact match in snippet view article find links to article
resulting from this cleavage induces a pro-inflammatory form of programmed cell death distinct from apoptosis, referred to as pyroptosis, and is responsible
Identification of cell death (1,397 words) [view diff] exact match in snippet view article find links to article
and proteins and a loss of compartmentalization. Apoptosis, or programmed cell death, is generally characterized by distinct morphological characteristics
Immunologic checkpoint (385 words) [view diff] exact match in snippet view article find links to article
CD152), which is an inhibitory receptor found on immune cells and programmed cell death 1 (CD279), which has an important role in down-regulating the immune
Arenobufagin (1,480 words) [view diff] exact match in snippet view article find links to article
a high Bax/Bcl-2 ratio, which is associated with apoptosis, or programmed cell death. Bax translocation from cytosol to mitochondria was also found to
Hok/sok system (1,438 words) [view diff] exact match in snippet view article find links to article
Hayes F (September 2003). "Toxins-antitoxins: plasmid maintenance, programmed cell death, and cell cycle arrest". Science. 301 (5639): 1496–9. doi:10.1126/science
Mitosis (7,064 words) [view diff] exact match in snippet view article find links to article
multiplication). Other errors during mitosis can induce apoptosis (programmed cell death) or cause mutations. Certain types of cancer can arise from such
ADP/ATP translocase 4 (1,607 words) [view diff] exact match in snippet view article find links to article
mitochondrial death pathway and cardiac myocyte apoptosis signaling. Programmed cell death is a distinct genetic and biochemical pathway essential to metazoans
Imatinib (5,839 words) [view diff] exact match in snippet view article find links to article
the Bcr-Abl tyrosine-kinase. This can slow growth or result in programmed cell death of certain types of cancer cells. Imatinib was approved for medical
Calliphora vomitoria (3,215 words) [view diff] exact match in snippet view article find links to article
the fly, such as cell death. While it is commonly believed that programmed cell death and apoptosis are the same, they are not always so. At the beginning
Angiotensin II receptor type 2 (1,900 words) [view diff] exact match in snippet view article find links to article
mediated by the renin–angiotensin system. This receptor mediates programmed cell death (apoptosis). In adults, it is highly expressed in myometrium with
Megagametogenesis (1,082 words) [view diff] exact match in snippet view article find links to article
cells are involved with nourishing the embryo, but often undergo programmed cell death before fertilization occurs. Cell plates form around the antipodal
ZBP1 (897 words) [view diff] exact match in snippet view article find links to article
sensor of influenza virus triggering the NLRP3 inflammasome and programmed cell death pathways". Science Immunology. 1 (2): aag2045. doi:10.1126/sciimmunol
Tropomyosin receptor kinase A (3,264 words) [view diff] exact match in snippet view article find links to article
differentiation, neural proliferation, nociceptor response, and avoidance of programmed cell death. The binding of NGF to TrkA leads to a ligand-induced dimerization
Molecular mimicry (3,882 words) [view diff] exact match in snippet view article find links to article
think that many autoimmune diseases are due to mutations governing programmed cell death, or to environmental products that injure target tissues, thus causing
ACER3 (326 words) [view diff] exact match in snippet view article find links to article
proliferation • inflammatory response • myelination • regulation of programmed cell death • ceramide catabolic process • lipid metabolism • sphingolipid metabolic
DNASE1L3 (724 words) [view diff] exact match in snippet view article find links to article
process • DNA catabolic process • programmed cell death involved in cell development • apoptotic process • programmed cell death • apoptotic DNA fragmentation
Pd1 (58 words) [view diff] exact match in snippet view article find links to article
refer to: Prussian S 3 a 19th-century steam locomotive PD-1 the Programmed cell death protein 1 receptor This disambiguation page lists articles associated
Giardiasis (5,038 words) [view diff] exact match in snippet view article find links to article
changes to the microvillus, increased intestinal permeability, and programmed cell death of small intestinal epithelial cells. Both trophozoites and cysts
Webbed toes (568 words) [view diff] exact match in snippet view article find links to article
webbed fingers and webbed toes. Syndactyly occurs when apoptosis or programmed cell death during gestation is absent or incomplete. Webbed toes occur most
VDAC3 (2,533 words) [view diff] exact match in snippet view article find links to article
mitochondrial death pathway and cardiac myocyte apoptosis signaling. Programmed cell death is a distinct genetic and biochemical pathway essential to metazoans
VDAC2 (2,629 words) [view diff] exact match in snippet view article find links to article
mitochondrial death pathway and cardiac myocyte apoptosis signaling. Programmed cell death is a distinct genetic and biochemical pathway essential to metazoans
Ced-12 (1,437 words) [view diff] exact match in snippet view article find links to article
apoptosis has been triggered in a cell. Apoptosis, also known as programmed cell death, activates during development as well as in situations where a cell
Mixed lineage kinase domain like pseudokinase (774 words) [view diff] exact match in snippet view article find links to article
critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (RIP3)
MAPK14 (5,241 words) [view diff] exact match in snippet view article find links to article
implicated in diverse cellular function, from gene expression to programmed cell death through a network of signaling molecules and transcription factors
Lymphoproliferative disorders (763 words) [view diff] exact match in snippet view article find links to article
shown to play a central role in the physiological regulation of programmed cell death. Normally, stimulation of recently activated T cells by antigen
IAP (438 words) [view diff] exact match in snippet view article find links to article
Inhibitor of apoptosis, a protein family involved in the suppression of programmed cell death (apoptosis) Integrated automation platform Integrin Associated Protein
Jasmonate (2,535 words) [view diff] exact match in snippet view article find links to article
mitochondria membranes and compromise the cell by causing apoptosis, or programmed cell death. JAs' roles in these processes are suggestive of methods by which
GSDMC (128 words) [view diff] exact match in snippet view article find links to article
organizing center • cytosol • plasma membrane • membrane Biological process • programmed cell death • biological process • pyroptosis Sources:Amigo / QuickGO
EIF4G2 (1,110 words) [view diff] exact match in snippet view article find links to article
4G isolated as a putative modulator of gamma interferon-induced programmed cell death". Mol. Cell. Biol. 17 (3): 1615–25. doi:10.1128/mcb.17.3.1615. PMC 231887
PKM2 (4,510 words) [view diff] exact match in snippet view article find links to article
analogue, H2O2, or UV light has been linked with caspase-independent programmed cell death. PKM2 is expressed in most human tumors. Initially, a switch from
ENDOG (2,404 words) [view diff] exact match in snippet view article find links to article
mitochondrial death pathway and cardiac myocyte apoptosis signaling. Programmed cell death is a distinct genetic and biochemical pathway essential to metazoans
Chris J. Leaver (1,144 words) [view diff] exact match in snippet view article find links to article
from the mitochondria to the cytosol occurs during heat-induced programmed cell death in cucumber plants". FEBS Letters. 463 (1–2): 151–154. doi:10
Conidium (1,027 words) [view diff] exact match in snippet view article find links to article
immunity in the lung relies on targeting fungal apoptosis-like programmed cell death". Science. 357 (6355): 1037–1041. Bibcode:2017Sci...357.1037S. doi:10
NPHP3 (587 words) [view diff] exact match in snippet view article find links to article
class of P-loop NTPases including animal and plant regulators of programmed cell death: multiple, complex domain architectures, unusual phyletic patterns
Plant embryogenesis (2,412 words) [view diff] exact match in snippet view article find links to article
continued growth of the cotyledons and axis elongation. In addition, programmed cell death must occur during this stage. This is carried out throughout the
Thirumala-Devi Kanneganti (3,005 words) [view diff] exact match in snippet view article find links to article
'optosis', a form of programmed cell death). PANoptosis is defined as a unique, physiologically relevant, inflammatory programmed cell death pathway activated
Alpha-Eleostearic acid (456 words) [view diff] exact match in snippet view article find links to article
conjugated linoleic acid. The compound has been found to induce programmed cell death of fat cells, and of HL60 leukemia cells in vitro at a concentration
Gasdermin A (111 words) [view diff] exact match in snippet view article find links to article
cytoplasm • cytosol • plasma membrane • membrane Biological process • programmed cell death • apoptotic process • pyroptosis Sources:Amigo / QuickGO
Rakesh Bhatnagar (273 words) [view diff] case mismatch in snippet view article find links to article
Biology of Infectious Diseases, Recombinant Vaccine Development, and Programmed Cell Death in Prokaryotes. Kumar, Mamidala Jagadesh (1 August 2016). "Prof
Ischemic cell death (1,093 words) [view diff] exact match in snippet view article find links to article
caused by a failure in ion transporter function. Apoptosis, or programmed cell death involves a series of cell shrinking processes, beginning with cell
Egg cell (1,440 words) [view diff] exact match in snippet view article find links to article
and organelles to the oocytes. This transfer is followed by the programmed cell death (apoptosis) of the nurse cells. During oogenesis, 15 nurse cells
Cysteine protease (1,171 words) [view diff] exact match in snippet view article find links to article
other animals, they are responsible for senescence and apoptosis (programmed cell death), MHC class II immune responses, prohormone processing, and extracellular
GSDMB (172 words) [view diff] exact match in snippet view article find links to article
plasma membrane • membrane • cellular component Biological process • programmed cell death • biological process • pyroptosis Sources:Amigo / QuickGO
Canine coronavirus (1,057 words) [view diff] exact match in snippet view article find links to article
Intestinal disease may be related to virus-induced apoptosis (programmed cell death) of cells of the epithelial mucosa of the small intestine. Canine
Hugh McDevitt (603 words) [view diff] exact match in snippet view article find links to article
can trigger the onset of type-1 diabetes. "A normal process - programmed cell death - causes a normal response," McDevitt said. "But it does this in
TRPM7 (420 words) [view diff] exact match in snippet view article find links to article
magnesium ion homeostasis • calcium-dependent cell-matrix adhesion • programmed cell death • phosphorylation • actomyosin structure organization • cation transport
Caspase 2 (918 words) [view diff] exact match in snippet view article find links to article
• positive regulation of apoptotic process • ectopic germ cell programmed cell death • apoptotic signaling pathway • neural retina development • apoptotic
Blocking antibody (718 words) [view diff] no match in snippet view article find links to article
function. Some new treatments hypothesize the blocking of PD-1, a programmed cell-death protein, which will result in longer-lived T-cells. The blocking
EVA1A (210 words) [view diff] exact match in snippet view article find links to article
Aliases EVA1A, FAM176A, TMEM166, eva-1 homolog A, regulator of programmed cell death External IDs MGI: 2385247 HomoloGene: 12969 GeneCards: EVA1A Orthologs
MARK4 (843 words) [view diff] exact match in snippet view article find links to article
midbody Biological process • phosphorylation • positive regulation of programmed cell death • nervous system development • protein phosphorylation • microtubule
Topoisomerase (3,084 words) [view diff] exact match in snippet view article find links to article
cells. The mitochondria generate ATP as well as playing a role in programmed cell death and aging. The mitochondrial DNA of animal cells is a circular,
CAPN3 (1,371 words) [view diff] exact match in snippet view article find links to article
kinase/NF-kappaB signaling • apoptotic process • signal transduction • programmed cell death • protein-containing complex assembly • protein catabolic process
Nivolumab (4,110 words) [view diff] exact match in snippet view article find links to article
activated T cells. If another molecule, called programmed cell death 1 ligand 1 or programmed cell death 1 ligand 2 (PD-L1 or PD-L2), binds to PD-1, the
Pib2 (1,004 words) [view diff] exact match in snippet view article find links to article
PMID 25735653. S2CID 11609431. van Doorn WG (October 2011). "Classes of programmed cell death in plants, compared to those in animals". Journal of Experimental
Heme C (886 words) [view diff] exact match in snippet view article find links to article
cytoplasmic cytochrome c, which must still contain heme C, leads to programmed cell death. Cytochrome c can be measured in human serum and can be used as
PGAM5 (107 words) [view diff] exact match in snippet view article find links to article
protein dephosphorylation • GO:0060554, GO:0060555 necroptosis • programmed cell death • dephosphorylation • GO:0032320, GO:0032321, GO:0032855, GO:0043089
Rohon-Beard cell (278 words) [view diff] exact match in snippet view article find links to article
2004). "Slow degeneration of zebrafish Rohon-Beard neurons during programmed cell death". Dev Dyn. 229 (1): 30–41. doi:10.1002/dvdy.10488. PMID 14699575
BCL2-like 1 (2,210 words) [view diff] case mismatch in snippet view article find links to article
INHIBITOR OF PROGRAMMED CELL DEATH, MINIMIZED AVERAGE STRUCTURE 1maz: X-RAY STRUCTURE OF BCL-XL, AN INHIBITOR OF PROGRAMMED CELL DEATH 1pq0: Crystal
Undercard (album) (213 words) [view diff] case mismatch in snippet view article
"Cruiserweights" "Only Existing Footage" "Communicating Doors" "Programmed Cell Death" "How I Left the Ministry" "Some Other Way" "Ambivalent Landscape
Prolidase deficiency (1,130 words) [view diff] no match in snippet view article find links to article
proposed that the buildup of non-degraded dipeptides might induce programmed cell-death (apoptosis), whereafter the cell's contents would be expelled into
Anti-dsDNA antibodies (2,919 words) [view diff] exact match in snippet view article find links to article
extracellular DNA. Apoptosis is the highly organised process of programmed cell death in which the cell degrades the nuclear DNA and signals for phagocytosis
Avelumab (1,431 words) [view diff] exact match in snippet view article find links to article
death-ligand 1 (PD-L1) and therefore inhibits binding to its receptor programmed cell death 1 (PD-1). Formation of a PD-1/PD-L1 receptor/ligand complex leads
PPIF (1,580 words) [view diff] exact match in snippet view article find links to article
regulation of apoptotic process • cellular response to calcium ion • programmed cell death • negative regulation of intrinsic apoptotic signaling pathway •
Corneal keratocyte (1,357 words) [view diff] exact match in snippet view article find links to article
process that attracts special attention. In a healthy cornea the programmed cell death is a rare occasion, but immediately after an injury to the uppermost
Spontaneous remission (1,059 words) [view diff] exact match in snippet view article find links to article
explains the occurrence of spontaneous regression." Apoptosis (programmed cell death) and angiogenesis (growth of new blood vessels) are sometimes discussed
2002 in science (1,418 words) [view diff] exact match in snippet view article find links to article
discoveries concerning genetic regulation of organ development and programmed cell death" Turing Award: Ron Rivest, Adi Shamir, and Leonard Adleman Wollaston
SPATA2 (416 words) [view diff] exact match in snippet view article find links to article
regulation of necroptotic process • protein K63-linked deubiquitination • protein linear deubiquitination • programmed cell death Sources:Amigo / QuickGO
Erythropoiesis (1,479 words) [view diff] exact match in snippet view article find links to article
Föller; Stephan M. Huber; Florian Lang (August 2008). "Erythrocyte programmed cell death". IUBMB Life. 60 (10): 661–668. doi:10.1002/iub.106. PMID 18720418
Aspergillus nidulans (761 words) [view diff] exact match in snippet view article find links to article
caspase-like proteases were isolated from A. nidulans samples under which programmed cell death had been induced. Findings such as these play a key role in determining
SOD2 (3,219 words) [view diff] exact match in snippet view article find links to article
mitochondrial death pathway and cardiac myocyte apoptosis signaling. Programmed cell death is a distinct genetic and biochemical pathway essential to metazoans
Procarbazine (740 words) [view diff] exact match in snippet view article find links to article
Proliferating cancer cells need to replicate their DNA and undergo programmed cell death (apoptosis) in response to DNA strand breaks. Normal or non-proliferating
Death effector domain (2,404 words) [view diff] exact match in snippet view article find links to article
both life and death cell decisions. Apoptosis is a controlled and programmed cell death that confers advantages during an organism lifecycle. The extrinsic
Chemotherapy (16,701 words) [view diff] exact match in snippet view article find links to article
to repair it, the DNA strands can break. This leads to a form of programmed cell death called apoptosis. Alkylating agents will work at any point in the
Pathophysiology of HIV/AIDS (1,838 words) [view diff] exact match in snippet view article find links to article
inflammasomes and inducing pyroptosis, a highly inflammatory form of programmed cell death. These findings cast CD4 T-cell death during HIV infection in a
ETS transcription factor family (1,020 words) [view diff] exact match in snippet view article find links to article
cell cycle control, cell migration, cell proliferation, apoptosis (programmed cell death) and angiogenesis. Multiple ETS factors have been found to be associated
LARP6 (354 words) [view diff] exact match in snippet view article find links to article
novel member of the Lupus Antigen family, is induced during the programmed cell death of skeletal muscles in the moth Manduca sexta". Gene. 393 (1–2):
POU4F2 (992 words) [view diff] exact match in snippet view article find links to article
of transcription by RNA polymerase II • positive regulation of programmed cell death • negative regulation of cell differentiation • positive regulation
Pioneer neuron (350 words) [view diff] no match in snippet view article find links to article
appropriate target. In many systems pioneer neurons are eliminated by programmed cell-death and are not present in the adult. Neural development Meyer G, Soria
Caspase-2 (378 words) [view diff] exact match in snippet view article find links to article
Ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell death". Cell. 78 (5): 739–50. doi:10.1016/S0092-8674(94)90422-7. PMID 8087842
Proteasome (12,317 words) [view diff] exact match in snippet view article find links to article
and external signals can lead to the induction of apoptosis, or programmed cell death. The resulting deconstruction of cellular components is primarily
Central nervous system cavernous hemangioma (1,679 words) [view diff] exact match in snippet view article find links to article
the most recently identified CCM gene . CCM3 is known as PDCD10 (programmed cell death 10), which was initially identified as a gene that is up-regulated
John Savill (748 words) [view diff] exact match in snippet view article find links to article
"Macrophage phagocytosis of aging neutrophils in inflammation. Programmed cell death in the neutrophil leads to its recognition by macrophages". Journal
Integrin beta 5 (1,175 words) [view diff] exact match in snippet view article find links to article
Pasqualini Renata (May 2003). "Alpha v beta 5 integrin-dependent programmed cell death triggered by a peptide mimic of annexin V". Mol. Cell. 11 (5): 1151–62
DNAJC3 (1,471 words) [view diff] exact match in snippet view article find links to article
processes. It plays an important role during embryonal development as programmed cell death and accompanies a variety of normal involutional processes in which
PHLDA1 (616 words) [view diff] case mismatch in snippet view article find links to article
"TDAG51 Is Induced by Homocysteine, Promotes Detachment-mediated Programmed Cell Death, and Contributes to the Development of Atherosclerosis in Hyperhomocysteinemia"
Heterophyes heterophyes (1,548 words) [view diff] exact match in snippet view article find links to article
NF-jB. Caspase-3 and NF-jB are protein that are essential to induce programmed cell death, apoptosis. Diagnosis done by stool examination is difficult when
STAT5 (1,215 words) [view diff] exact match in snippet view article find links to article
with: controlled cell growth and division, or cell proliferation programmed cell death, or apoptosis cell specialization, or differentiation and inflammation
School of Medical Sciences, University of Manchester (1,092 words) [view diff] exact match in snippet view article find links to article
discoveries concerning 'genetic regulation of organ development and programmed cell death'. Raymond Tallis, gerontologist. Nesta Wells, first British female
Zeta toxin protein domain (336 words) [view diff] exact match in snippet view article find links to article
, Shoeman, R.L. and Meinhart, A. (2011). "A novel mechanism of programmed cell death in bacteria by toxin-antitoxin systems corrupts peptidoglycan synthesis"
Nucleoside-modified messenger RNA (1,757 words) [view diff] exact match in snippet view article find links to article
interferon and TNF-alpha, and when sufficiently intense lead to programmed cell death. The inflammatory nature of exogenous RNA can be masked by modifying
Antamanide (688 words) [view diff] exact match in snippet view article find links to article
to determine whether the antamanide also inhibits the apoptosis (programmed cell death) of human cervical carcinoma cells caused by the permeability transition
Obligate parasite (2,099 words) [view diff] exact match in snippet view article find links to article
to reduce the replication and spread of pathogens is apoptosis (programmed cell death). Some obligate parasites have developed ways to suppress this phenomenon
IFI16 (1,363 words) [view diff] exact match in snippet view article find links to article
helper CD4 T cells by pyroptosis, a highly inflammatory form of programmed cell death. Recently, it has been shown how IFI16, once extracellularly released
Ancrod (1,790 words) [view diff] exact match in snippet view article find links to article
that the substance has interesting apoptotic properties (causing programmed cell death), which remain to be explored. The half-life of ancrod is 3 to 5
Chromosome 19 (2,374 words) [view diff] exact match in snippet view article find links to article
receptor PALM: encoding protein Paralemmin PDCD5: encoding protein Programmed cell death protein 5 PEX11G: peroxisomal biogenesis factor 11 gamma PGK1P2:
Phycodnaviridae (9,306 words) [view diff] exact match in snippet view article find links to article
viral sphingolipids produced during the lytic stage are involved in programmed cell death in coccolithophore populations. A high correlation was found between
Growth factor (1,112 words) [view diff] exact match in snippet view article find links to article
are used as "death" signals; they cause target cells to undergo programmed cell death or apoptosis. The growth factor was first discovered by Rita Levi-Montalcini
Omigapil (2,239 words) [view diff] exact match in snippet view article find links to article
Kingdom at Great Ormond Street Hospital (UCL). Omigapil inhibits programmed cell death (apoptosis) through the enzymes glyceraldehyde 3-phosphate dehydrogenase
Chromosome 3 (1,743 words) [view diff] exact match in snippet view article find links to article
PCCB: propionyl Coenzyme A carboxylase, beta polypeptide PDCD10: programmed cell death 10 PIK3CA: phosphoinositide-3-kinase, catalytic, alpha polypeptide
MIR22HG (2,491 words) [view diff] exact match in snippet view article find links to article
type to another, usually more mature, cell type), apoptosis (i.e. programmed cell death), and the expression of various genes through chromatin remodeling
Phytoalexin (1,654 words) [view diff] exact match in snippet view article find links to article
surrounding the site of infection are signaled to undergo apoptosis, or programmed cell death, in order to prevent the spread of the pathogen to the rest of the
APBB2 (645 words) [view diff] exact match in snippet view article find links to article
FE65-like protein 1 regulates both apoptotic and caspase-independent programmed cell death mediated by tumor necrosis factor". Biochem. Biophys. Res. Commun
Nuclear bodies (1,579 words) [view diff] exact match in snippet view article find links to article
it is targeted to dots. whereas overexpression of PML results in programmed cell death. One hypothesized function of the dots is as a 'nuclear dump' or
Gregori Aminoff Prize (146 words) [view diff] exact match in snippet view article find links to article
crystallographic studies of proteins and protein complexes that regulate programmed cell death" 2015 Ian Robinson (United Kingdom) "for his development of diffraction
DAD1 (682 words) [view diff] exact match in snippet view article find links to article
cell death, was initially identified as a negative regulator of programmed cell death in the temperature sensitive tsBN7 cell line. The DAD1 protein disappeared
RAB9A (869 words) [view diff] exact match in snippet view article find links to article
"A tomato homologue of the human protein PIRIN is induced during programmed cell death". Plant Mol. Biol. 46 (4): 459–68. doi:10.1023/A:1010618515051.
Embryomics (2,179 words) [view diff] exact match in snippet view article find links to article
into mature adult somatic cell types, or which disappear due to programmed cell death (apoptosis). The entire process of embryogenesis can be described
Retinoic acid receptor gamma (1,088 words) [view diff] exact match in snippet view article find links to article
positive regulation of apoptotic process • positive regulation of programmed cell death • cellular response to leukemia inhibitory factor • multicellular
Ben Barres (3,202 words) [view diff] exact match in snippet view article find links to article
connections with their targets. These studies investigated how this programmed cell death, apoptosis, occurred in such a tremendous scale. Additionally, he
Mebendazole (1,590 words) [view diff] exact match in snippet view article find links to article
which allows pro-apoptotic protein Bax to dimerize and initiate programmed cell death. Mebendazole is available as a generic medication. Mebendazole is
Antimutagen (977 words) [view diff] exact match in snippet view article find links to article
nucleotide excision repair such as XPA and XPC; Selenium: Induces programmed cell death via many signalling pathways as well as protects the cells against
ANKRD25 (524 words) [view diff] exact match in snippet view article find links to article
G1/S transition of mitotic cell cycle • negative regulation of programmed cell death • negative regulation of intracellular estrogen receptor signaling
Senolytic (1,448 words) [view diff] exact match in snippet view article find links to article
cytosol where it would activate caspases, leading to apoptosis (programmed cell death). Instead, retention of p53 in the nucleus by FOXO4 promotes cellular
Dz13 (1,065 words) [view diff] case mismatch in snippet view article find links to article
Cytotoxicity in Endothelial Cells with Features of Nonapoptotic Programmed Cell Death. Oligonucleotides 18(3), 257-268. Fahmy, R. et al (2006) Suppression
UDP-N-acetylglucosamine kinase (278 words) [view diff] exact match in snippet view article find links to article
Gebhardt M, Shoeman RL, Meinhart A (March 2011). "A novel mechanism of programmed cell death in bacteria by toxin-antitoxin systems corrupts peptidoglycan synthesis"
DNA damage-inducible transcript 3 (5,471 words) [view diff] exact match in snippet view article find links to article
PMC 4284148. PMID 24994655. Elmore S (June 2007). "Apoptosis: a review of programmed cell death". Toxicologic Pathology. 35 (4): 495–516. doi:10.1080/01926230701320337
HAVCR2 (2,716 words) [view diff] exact match in snippet view article find links to article
checkpoint and together with other inhibitory receptors including programmed cell death protein 1 (PD-1) and lymphocyte activation gene 3 protein (LAG3)
Aortic aneurysm (2,810 words) [view diff] exact match in snippet view article find links to article
short, raising HDL cholesterol is beneficial because it induces programmed cell death. The walls of a failing aorta are replaced and strengthened. New
Anal cancer (2,485 words) [view diff] exact match in snippet view article find links to article
speculate that smoking interferes with a process called apoptosis, or programmed cell death, which helps rid the body of abnormal cells that could turn cancerous
Retinoic acid receptor beta (1,268 words) [view diff] exact match in snippet view article find links to article
organism growth • embryonic eye morphogenesis • positive regulation of programmed cell death • negative regulation of apoptotic process • negative regulation
6-Diazo-5-oxo-L-norleucine (964 words) [view diff] exact match in snippet view article find links to article
could be shown in vitro that DON treatment led to apoptosis, the programmed cell death. Different pathways were investigated. So it could be shown that
Retinoic acid receptor beta (1,268 words) [view diff] exact match in snippet view article find links to article
organism growth • embryonic eye morphogenesis • positive regulation of programmed cell death • negative regulation of apoptotic process • negative regulation
Animal testing on invertebrates (899 words) [view diff] exact match in snippet view article find links to article
programmed to die during development, leading to the discovery that programmed cell death is an active process under genetic control. The simple nervous system
PLCG2 (1,366 words) [view diff] exact match in snippet view article find links to article
phosphatidylinositol biosynthetic process • negative regulation of programmed cell death • B cell differentiation • T cell receptor signaling pathway • activation
The Extra Lens (357 words) [view diff] case mismatch in snippet view article find links to article
"Cruiserweights", "Only Existing Footage", "Communicating Doors", "Programmed Cell Death", "How I Left the Ministry", "Some Other Way", "Ambivalent Landscape
Efferocytosis (621 words) [view diff] exact match in snippet view article find links to article
inflammation). deCathelineau AM, Henson PM (2003). "The final step in programmed cell death: phagocytes carry apoptotic cells to the grave". Essays Biochem
Betulinic acid (1,827 words) [view diff] exact match in snippet view article find links to article
PMID 12118187. Tan Y, Yu R, Pezzuto JM (July 2003). "Betulinic acid-induced programmed cell death in human melanoma cells involves mitogen-activated protein kinase
Geoffrey M. Cooper (644 words) [view diff] exact match in snippet view article find links to article
Erhardt, P., Schremser, E.J., and Cooper, G.M. 1999. B-Raf inhibits programmed cell death downstream of cytochrome c release from mitochondria by activating
PAX2 (1,853 words) [view diff] exact match in snippet view article find links to article
development • cell fate determination • negative regulation of programmed cell death • vestibulocochlear nerve formation • camera-type eye development
DNA fragmentation (1,478 words) [view diff] exact match in snippet view article find links to article
fragmentation is a natural fragmentation that cells perform in apoptosis (programmed cell death). DNA fragmentation is a biochemical hallmark of apoptosis. In dying
Bortezomib (2,136 words) [view diff] exact match in snippet view article find links to article
prevent degradation of pro-apoptotic factors, thereby triggering programmed cell death in neoplastic cells. Recently, it was found that bortezomib caused
DFNA5 (917 words) [view diff] exact match in snippet view article find links to article
pathway • negative regulation of cell population proliferation • programmed cell death • cell death • positive regulation of MAPK cascade • necrotic cell
Lipid signaling (5,620 words) [view diff] exact match in snippet view article find links to article
mediates many cell-stress responses, including the regulation of programmed cell death (apoptosis) and cell aging (senescence). Numerous research works
Serine/threonine-specific protein kinase (962 words) [view diff] exact match in snippet view article find links to article
receptors play a role in the regulation of cell proliferation, programmed cell death (apoptosis), cell differentiation, and embryonic development. While
Osteocyte (2,364 words) [view diff] exact match in snippet view article find links to article
a consequence of senescence, degeneration/necrosis, apoptosis (programmed cell death), and/or osteoclastic engulfment. The percentage of dead osteocytes
Trichothecene (5,532 words) [view diff] exact match in snippet view article find links to article
which inevitably leads to oxidative stress and induction of the programmed cell death pathway, apoptosis. The induction of apoptosis in cells with high
Ubiquitin carboxy-terminal hydrolase L1 (2,634 words) [view diff] exact match in snippet view article find links to article
Uchl1 increases the susceptibility of pancreatic beta-cells to programmed cell death, indicating that this protein plays a protective role in neuroendocrine
Cell biology (3,127 words) [view diff] exact match in snippet view article find links to article
cell damage, terminal differentiation as occurs in nerve cells, or programmed cell death (apoptosis) during development. Maintenance of cell division potential
Benign tumor (2,676 words) [view diff] exact match in snippet view article find links to article
in cell proliferation, differentiation, migration and apoptosis (programmed cell death), causing the growth of benign tumors. Tuberous sclerosis complex
Death-associated protein 6 (1,526 words) [view diff] exact match in snippet view article find links to article
death. It is also essential for development of nerval system by programmed cell death. The real apoptotic process starts after activating this pathway
Anti-neutrophil cytoplasmic antibody (2,053 words) [view diff] exact match in snippet view article find links to article
considered a type II hypersensitivity reaction. Neutrophil apoptosis, or programmed cell death, is vital in controlling the duration of the early inflammatory
RIPK3 (774 words) [view diff] exact match in snippet view article find links to article
of intrinsic apoptotic signaling pathway • signal transduction • programmed cell death • positive regulation of necrotic cell death • positive regulation
Annexin A5 affinity assay (851 words) [view diff] exact match in snippet view article find links to article
only on the inner leaflet of the membrane. Apoptosis is a form of programmed cell death that is used by the body to remove unwanted, damaged, or senescent
Biological life cycle (2,840 words) [view diff] exact match in snippet view article find links to article
cell damage, terminal differentiation as occurs in nerve cells, or programmed cell death (apoptosis) during development. Maintenance of cell division potential
Addiction module (699 words) [view diff] exact match in snippet view article find links to article
Engelberg-Kulka, Hanna; Gad Glaser (October 1999). "Addiction modules and programmed cell death and antideath in bacterial cultures". Annual Review of Microbiology
Christopher E. Rudd (893 words) [view diff] exact match in snippet view article find links to article
synthase kinase-3 (GSK-3) to down-regulate the inhibitory co-receptor programmed cell death-1 (PD-1) in cancer immunotherapy. Rudd's work has had important
Li–Fraumeni syndrome (2,248 words) [view diff] exact match in snippet view article find links to article
for DNA repair to be able to take place or to cause apoptosis (programmed cell death). LFS-L: Families who do not conform to the criteria of classical
FOXO3 (2,183 words) [view diff] exact match in snippet view article find links to article
apoptotic process • positive regulation of hydrogen peroxide-mediated programmed cell death • response to dexamethasone • cellular response to nerve growth
TMBIM4 (1,016 words) [view diff] exact match in snippet view article find links to article
protein present in the Golgi that helps regulate apoptosis, a form of programmed cell death. By regulating the fluxes of Ca+2, an increase of GAAP can help
MicroRNA 425 (546 words) [view diff] case mismatch in snippet view article find links to article
regulates chemoresistance in colorectal cancer cells via regulation of Programmed Cell Death 10". J. Cell. Mol. Med. 20 (2): 360–9. doi:10.1111/jcmm.12742. PMC 4727563
DLC1 (3,154 words) [view diff] exact match in snippet view article find links to article
phosphorylation is as yet unknown. DLC1 is responsible for inducing programmed cell death by at least two mechanisms: caspase-3-mediated apoptosis and Bcl-2
Ciliary neurotrophic factor (1,731 words) [view diff] exact match in snippet view article find links to article
morphogenesis • neuron development • regulation of retinal cell programmed cell death • nervous system development • ciliary neurotrophic factor-mediated
Venetoclax (2,327 words) [view diff] exact match in snippet view article find links to article
the anti-apoptotic B-cell lymphoma-2 (Bcl-2) protein, leading to programmed cell death of CLL cells. Overexpression of Bcl-2 in some lymphoid malignancies
AV-HALT (793 words) [view diff] exact match in snippet view article find links to article
Capron, A (1991). "Cell dysfunction and depletion in AIDS: The programmed cell death hypothesis". Immunology Today. 12 (4): 102–5. doi:10.1016/0167-5699(91)90092-8
DCPS (gene) (1,043 words) [view diff] exact match in snippet view article
process • mRNA cis splicing, via spliceosome • negative regulation of programmed cell death • mRNA processing • nuclear-transcribed mRNA catabolic process,
MAGED1 (1,188 words) [view diff] exact match in snippet view article find links to article
demonstrated to be involved in the p75 neurotrophin receptor mediated programmed cell death pathway. Three transcript variants encoding two different isoforms
POU4F1 (2,166 words) [view diff] exact match in snippet view article find links to article
of transcription by RNA polymerase II • negative regulation of programmed cell death • positive regulation of osteoclast differentiation • regulation
DNAJA3 (1,939 words) [view diff] exact match in snippet view article find links to article
positive regulation of apoptotic process • negative regulation of programmed cell death • GO:0048552 regulation of catalytic activity • negative regulation
Caenorhabditis elegans (8,986 words) [view diff] exact match in snippet view article find links to article
a very popular model system for studying developmental biology. Programmed cell death (apoptosis) eliminates many additional cells (131 in the hermaphrodite
Cell cycle withdrawal (2,150 words) [view diff] exact match in snippet view article find links to article
cells to stop their functions and differentiations to undergo a programmed cell death process called apoptosis. Furthermore, the withdrawal process could
Breast cancer (17,874 words) [view diff] exact match in snippet view article find links to article
and to die at the proper time. Normal cells will self-destruct (programmed cell death) when they are no longer needed. Until then, cells are protected
BAG1 (1,628 words) [view diff] exact match in snippet view article find links to article
protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred
Anti-nuclear antibody (6,060 words) [view diff] exact match in snippet view article find links to article
lymphocytes that recognise human proteins (autoantigens) either undergo programmed cell death (apoptosis) or become non-functional. This self-tolerance means
Josef Victor Rohon (407 words) [view diff] exact match in snippet view article find links to article
2004). "Slow degeneration of zebrafish Rohon-Beard neurons during programmed cell death". Developmental Dynamics. 229 (1): 30–41. doi:10.1002/dvdy.10488
Tillandsia paucifolia (788 words) [view diff] exact match in snippet view article find links to article
G.; Di Falco, P.; Brighigna, L. (2010). "Megasporogenesis and programmed cell death in tillandsia (bromeliacea)". Protoplasma. 248 (4): 651–662. doi:10
PAWR (1,347 words) [view diff] exact match in snippet view article find links to article
proliferation • positive regulation of hydrogen peroxide-mediated programmed cell death • positive regulation of apoptotic process Sources:Amigo / QuickGO
Osteopontin (7,467 words) [view diff] exact match in snippet view article find links to article
endothelial cells exposed to harmful stimuli. OPN prevents non-programmed cell death in inflammatory colitis. The fact that OPN interacts with multiple
Lina M. Obeid (855 words) [view diff] exact match in snippet view article find links to article
M., Corrine M. Linardic, Linda A. Karolak, and Yusuf A. Hannun "Programmed cell death induced by ceramide" Science, vol. 259, issue 5102, 1993, p. 1769-1771
CHEK2 (2,790 words) [view diff] exact match in snippet view article find links to article
the promyelocytic leukemia protein (PML) involved in apoptosis (programmed cell death). The CHK2 protein plays a critical role in the DNA damage checkpoint
B-cell prolymphocytic leukemia (2,383 words) [view diff] no match in snippet view article find links to article
checkpoint of the cell cycle as well as certain genes responsible for programmed-cell death (apoptosis). It is believed that mutations to TP53 are responsible
Myristoylation (2,199 words) [view diff] exact match in snippet view article find links to article
its receptor. Myristoylation is an integral part of apoptosis, or programmed cell death. Apoptosis is necessary for cell homeostasis and occurs when cells
Taurolidine (2,225 words) [view diff] exact match in snippet view article find links to article
Brock M, Möhler H (2003-06-01). "Enhancement of Fas-ligand-mediated programmed cell death by taurolidine". Anticancer Research. 23 (3B): 2309–14. PMID 12894508
RIPK1 (4,110 words) [view diff] exact match in snippet view article find links to article
extrinsic apoptotic signaling pathway • positive regulation of programmed cell death • tumor necrosis factor-mediated signaling pathway • positive regulation
STK24 (1,375 words) [view diff] exact match in snippet view article find links to article
regulation of multiple functions of the cells and interaction with programmed cell death 10 (CCM3). CCM is a pathological vascular situation that, influencing
XMEN disease (966 words) [view diff] case mismatch in snippet view article find links to article
Clinical trial number NCT00246857 for "Screening Protocol for Genetic Diseases of Lymphocyte Homeostasis and Programmed Cell Death" at ClinicalTrials.gov
Nucleoporin 62 (2,242 words) [view diff] exact match in snippet view article find links to article
kinase/NF-kappaB signaling • protein transport • negative regulation of programmed cell death • nuclear transport • GO:0022415 viral process • positive regulation
MYND zinc finger (558 words) [view diff] exact match in snippet view article find links to article
Cohen JJ (August 1991). "Identification of mRNAs associated with programmed cell death in immature thymocytes". Mol. Cell. Biol. 11 (8): 4177–88. doi:10
PDX1 (2,439 words) [view diff] exact match in snippet view article find links to article
be important in mediating the effect of insulin on the apoptotic programmed cell death of β-cells: a small concentration of insulin protects β-cells from
Transplant rejection (3,344 words) [view diff] exact match in snippet view article find links to article
recognize their matching epitope, and trigger the target cell's programmed cell death by apoptosis. Developed through an earlier primary exposure that
EIF4A1 (2,571 words) [view diff] exact match in snippet view article find links to article
3109/10409238.2014.887051. PMID 24520918. S2CID 207506515. "PDCD4 programmed cell death 4 [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Ali
HSPA1L (2,301 words) [view diff] exact match in snippet view article find links to article
processes. It plays an important role during embryonal development as programmed cell death and accompanies a variety of normal involutional processes in which
Bacterial effector protein (3,143 words) [view diff] exact match in snippet view article find links to article
reducing ER–Golgi transport (of IL-8 and other proteins). Apoptosis (programmed cell death). Apoptosis is usually a mechanism of defense to infection, given
FASTKD2 (933 words) [view diff] exact match in snippet view article find links to article
processes. It plays an important role during embryonal development as programmed cell death and accompanies a variety of normal involutional processes in which
Photorespiration (2,892 words) [view diff] exact match in snippet view article find links to article
responses controlling growth, environmental and defense responses, and programmed cell death. It has been postulated that photorespiration may function as a
Fox Chase Cancer Center (1,257 words) [view diff] exact match in snippet view article find links to article
and AKT2 genes - the first viral oncogenes described that inhibit programmed cell death. 1991 Timothy Yen discovers that a molecular motor controls the
Insulator (genetics) (2,004 words) [view diff] exact match in snippet view article
processes that are important for cell growth, cell differentiation, and programmed cell death (apoptosis). Two of these cell cycle regulation genes that are known
Colorectal cancer (13,001 words) [view diff] exact match in snippet view article find links to article
protein named BAX is mutated instead. Other proteins responsible for programmed cell death that are commonly deactivated in colorectal cancers are TGF-β and
Th 9 cell (3,136 words) [view diff] exact match in snippet view article find links to article
fully substitute the role of TGF-β in TH9 cells, then Jagged2, programmed cell death ligand (PD-L2), cyclooxy- genase (COX)-2, 1,25-dihydroxyvitamin
2002 in England (2,411 words) [view diff] exact match in snippet view article find links to article
discoveries concerning 'genetic regulation of organ development and programmed cell death'". Cherie Blair apologises for the embarrassment she caused in buying
Uncombable hair syndrome (2,640 words) [view diff] exact match in snippet view article find links to article
gene induces cell proliferation, migration, invasion, and promotes programmed cell death. This came to show that Transglutaminse 3 will be a candidate growth
Paraplegin (1,382 words) [view diff] exact match in snippet view article find links to article
permeability • mitochondrial outer membrane permeabilization involved in programmed cell death • mitochondrion organization • anterograde axonal transport Sources:Amigo
Translation (biology) (3,288 words) [view diff] exact match in snippet view article
cascade that can ultimately allow the cancer to escape apoptosis (programmed cell death) triggered by nutrition deprivation. Future cancer therapies may
Interleukin 1 beta (2,341 words) [view diff] exact match in snippet view article find links to article
colony-stimulating factor production • immune response • ectopic germ cell programmed cell death • leukocyte migration • lipopolysaccharide-mediated signaling pathway
Michael Karin (654 words) [view diff] exact match in snippet view article find links to article
immunity. Having found that IKK dependent NF-κB activation suppresses programmed cell death, Karin and colleagues postulated that NF-κB provided the long suspected
N. Louise Glass (663 words) [view diff] exact match in snippet view article find links to article
and molecular analyses of mating type, nonself recognition and programmed cell death in filamentous fungi. In 1999 she was recruited to the Plant and
Tumor suppressor gene (3,393 words) [view diff] exact match in snippet view article find links to article
induce apoptosis. If damage cannot be repaired, the cell initiates programmed cell death to remove the threat it poses to the organism as a whole. (e.g.
ParDE type II toxin-antitoxin system (396 words) [view diff] exact match in snippet view article find links to article
repressor. Toxin-antitoxin database Jensen RB, Gerdes K (1995). "Programmed cell death in bacteria: proteic plasmid stabilization systems". Mol Microbiol
WFS1 (1,186 words) [view diff] exact match in snippet view article find links to article
ERAD pathway • renal water homeostasis • negative regulation of programmed cell death • positive regulation of protein ubiquitination • negative regulation
IL1A (2,661 words) [view diff] exact match in snippet view article find links to article
apoptotic signaling pathway in absence of ligand • ectopic germ cell programmed cell death • positive regulation of vascular endothelial growth factor production
Eileen White (489 words) [view diff] exact match in snippet view article find links to article
that encodes Bcl-2, a mammalian protein that inhibits apoptosis, programmed cell death. She then joined Rutgers University as an assistant professor in
TxpA-RatA toxin-antitoxin system (569 words) [view diff] exact match in snippet view article find links to article
Hayes F (September 2003). "Toxins-antitoxins: plasmid maintenance, programmed cell death, and cell cycle arrest". Science. 301 (5639): 1496–1499. Bibcode:2003Sci
Hepatocyte growth factor (2,645 words) [view diff] exact match in snippet view article find links to article
apoptotic process • negative regulation of hydrogen peroxide-mediated programmed cell death • positive regulation of neuron projection regeneration • positive
Hormone (3,605 words) [view diff] exact match in snippet view article find links to article
circadian rhythms mood swings induction or suppression of apoptosis (programmed cell death) activation or inhibition of the immune system regulation of metabolism
Bcl-2-interacting killer (1,367 words) [view diff] exact match in snippet view article find links to article
proteins, such as BCL2 and the Epstein-Barr virus in order to enhance programmed cell death. Because its activity is suppressed in the presence of survival-promoting
AIFM1 (1,527 words) [view diff] exact match in snippet view article find links to article
"Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death". Nature. 410 (6828): 549–54. Bibcode:2001Natur.410..549J. doi:10