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Caspase 6
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to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 beta-converting enzyme". J. Biol. Chem. 269 (49): 30761–4. doi:10Fibroblast growth factor (3,124 words) [view diff] no match in snippet view article find links to article
crystal structures of FGF1 have been solved and found to be related to interleukin 1-beta. Both families have the same beta trefoil fold consisting of 12-strandedCD33 (889 words) [view diff] no match in snippet view article find links to article
transduction positive regulation of protein secretion negative regulation of interleukin-1 beta production negative regulation of interleukin-8 production negativeMNDA (793 words) [view diff] no match in snippet view article find links to article
activation of innate immune response cellular response to interferon-beta positive regulation of interleukin-1 beta production Sources:Amigo / QuickGOMethotrexate (3,397 words) [view diff] no match in snippet view article find links to article
function. Another mechanism of MTX is the inhibition of the binding of interleukin 1-beta to its cell surface receptor. Thereby, it acts as anticytokine. InTroponin C, skeletal muscle (607 words) [view diff] exact match in snippet view article find links to article
"Actin, troponin C, Alzheimer amyloid precursor protein and pro-interleukin 1 beta as substrates of the protease from human immunodeficiency virus".S1PR3 (927 words) [view diff] no match in snippet view article find links to article
sphingosine-1-phosphate receptor signaling pathway regulation of interleukin-1 beta production cytokine production inflammatory response Sources:AmigoHistory of apoptosis research (1,598 words) [view diff] no match in snippet view article find links to article
Shaham and Junying Yuan working in Horvitz's laboratory identified interleukin-1-beta-converting enzyme as the mammalian homolog of the CED-3 enzyme. InATP6V0A2 (838 words) [view diff] exact match in snippet view article find links to article
tolerance factor modulates the effect of adenosine triphosphate-induced interleukin 1 beta secretion in human macrophages". Hum. Immunol. 65 (7): 676–682. doi:10HOXB4 (1,024 words) [view diff] no match in snippet view article find links to article
human HOX-2 genes in B/T acute lymphoid leukemia and interleukin-2/interleukin-1 beta-stimulated natural killer lymphocytes". Blood. 80 (1): 185–93. doi:10CYP1B1 (1,185 words) [view diff] no match in snippet view article find links to article
"Targets for dioxin: genes for plasminogen activator inhibitor-2 and interleukin-1 beta". Science. 254 (5030): 415–8. Bibcode:1991Sci...254..415S. doi:10Cholesterol crystal (494 words) [view diff] no match in snippet view article find links to article
1161/CIRCRESAHA.115.306656. PMC 4793711. PMID 26837745. Libby P (2017). "Interleukin-1 Beta as a Target for Atherosclerosis Therapy: Biological Basis of CANTOSJunying Yuan (1,656 words) [view diff] no match in snippet view article find links to article
subsequently identified the mammalian homologue of ced-3 known as interleukin-1 beta-converting enzyme(ICE), later called caspase-1. Junying Yuan establishedCARD (domain) (1,429 words) [view diff] no match in snippet view article
[2][permanent dead link] caspase-1: apoptosis-related cysteine peptidase (interleukin 1, beta, convertase; ICE) [3][permanent dead link] caspase-2: apoptosis-relatedTartrate-resistant acid phosphatase (1,746 words) [view diff] no match in snippet view article find links to article
dephosphorylation response to lipopolysaccharide negative regulation of interleukin-1 beta production negative regulation of interleukin-12 production negativeIFI16 (1,383 words) [view diff] no match in snippet view article find links to article
regulation of transcription by RNA polymerase II positive regulation of interleukin-1 beta production regulation of transcription, DNA-templated regulation ofFarrowia (580 words) [view diff] no match in snippet view article find links to article
Matsuda, Yuzuru; Nakanishi, Satoshi (2003). "EI-1941-1 and -2, Novel Interleukin-1.BETA. Converting Enzyme Inhibitors Produced by Farrowia sp. E-1941: I.MT1E (766 words) [view diff] no match in snippet view article find links to article
7392. PMC 392152. PMID 6095291. Kondo Y, Kuo SM, Lazo JS (1994). "Interleukin-1 beta-mediated metallothionein induction and cytoprotection against cadmiumSignal-regulatory protein alpha (1,664 words) [view diff] no match in snippet view article find links to article
adhesion regulation of interferon-gamma production regulation of interleukin-1 beta production regulation of interleukin-6 production regulation of tumorGrowth hormone secretagogue receptor (1,608 words) [view diff] no match in snippet view article find links to article
component of synaptic membrane Biological process negative regulation of interleukin-1 beta production negative regulation of insulin secretion regulation ofACTG2 (1,017 words) [view diff] exact match in snippet view article find links to article
"Actin, troponin C, Alzheimer amyloid precursor protein and pro-interleukin 1 beta as substrates of the protease from human immunodeficiency virus".MAFF (gene) (1,840 words) [view diff] exact match in snippet view article
tissues. Human MAFF gene is induced by proinflammatory cytokines, interleukin 1 beta and tumor necrosis factor in myometrial cells. Because of sequenceH. Robert Horvitz (2,156 words) [view diff] no match in snippet view article find links to article
elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme". Cell. 75 (4): 641–52. doi:10.1016/0092-8674(93)90485-9Neonatal-onset multisystem inflammatory disease (1,193 words) [view diff] no match in snippet view article find links to article
Goldbach-Mansky, R. et al. Neonatal-Onset Multisystem Inflammatory Disease Responsive to Interleukin-1{beta} Inhibition N Engl J Med 2006 355: 581–592.NOD1 (937 words) [view diff] no match in snippet view article find links to article
complex oligomerization detection of bacterium positive regulation of interleukin-1 beta production positive regulation of ERK1 and ERK2 cascade positive regulationNLRP3 (1,736 words) [view diff] no match in snippet view article find links to article
T-helper 2 cell differentiation regulation of inflammatory response interleukin-1 beta production positive regulation of type 2 immune response inflammatoryGSTP1 (628 words) [view diff] no match in snippet view article find links to article
response to amino acid response to estradiol negative regulation of interleukin-1 beta production negative regulation of acute inflammatory response glutathioneNOD2 (1,530 words) [view diff] no match in snippet view article find links to article
interleukin-8 production detection of bacterium positive regulation of interleukin-1 beta production regulation of inflammatory response positive regulationActin, alpha skeletal muscle (1,505 words) [view diff] exact match in snippet view article find links to article
"Actin, troponin C, Alzheimer amyloid precursor protein and pro-interleukin 1 beta as substrates of the protease from human immunodeficiency virus".MEFV (1,128 words) [view diff] no match in snippet view article find links to article
regulation of cysteine-type endopeptidase activity negative regulation of interleukin-1 beta production response to interferon-gamma positive regulation of autophagyACTA2 (1,136 words) [view diff] exact match in snippet view article find links to article
"Actin, troponin C, Alzheimer amyloid precursor protein and pro-interleukin 1 beta as substrates of the protease from human immunodeficiency virus".Anemia of chronic disease (1,640 words) [view diff] exact match in snippet view article find links to article
"Mechanism of anaemia in rheumatoid arthritis: demonstration of raised interleukin 1 beta concentrations in anaemic patients and of interleukin 1 mediated suppressionERRFI1 (932 words) [view diff] no match in snippet view article find links to article
nucleus cytoplasm cytosol Biological process negative regulation of interleukin-1 beta production negative regulation of epidermal growth factor receptorAnthrax (10,239 words) [view diff] exact match in snippet view article find links to article
lethal factor was presumed to cause macrophages to make TNF-alpha and interleukin 1 beta (IL1B). TNF-alpha is a cytokine whose primary role is to regulateCaspase 8 (2,278 words) [view diff] no match in snippet view article find links to article
neuron death extrinsic apoptotic signaling pathway via death domain receptors positive regulation of interleukin-1 beta production Sources:Amigo / QuickGOACTC1 (2,007 words) [view diff] exact match in snippet view article find links to article
"Actin, troponin C, Alzheimer amyloid precursor protein and pro-interleukin 1 beta as substrates of the protease from human immunodeficiency virus".Fas receptor (2,675 words) [view diff] no match in snippet view article find links to article
amino terminus, which facilitates binding to the DED of FADD-like interleukin-1 beta-converting enzyme (FLICE), more commonly referred to as caspase-8Familial Mediterranean fever (2,650 words) [view diff] no match in snippet view article find links to article
daily colchicine regimen has been successful. Canakinumab, an anti-interleukin-1-beta monoclonal antibody, has likewise been shown to be effective in controllingProteinase-activated receptor 1 (2,285 words) [view diff] no match in snippet view article find links to article
healing positive regulation of ERK1 and ERK2 cascade regulation of interleukin-1 beta production positive regulation of I-kappaB kinase/NF-kappaB signalingSphingosine kinase 1 (1,115 words) [view diff] no match in snippet view article find links to article
positive regulation of cell population proliferation regulation of interleukin-1 beta production inflammatory response sphingoid catabolic process positiveCyclooxygenase-1 (2,122 words) [view diff] exact match in snippet view article find links to article
of the resulting transcripts by transforming growth factor beta 1, interleukin 1 beta, and tumor necrosis factor alpha". The Journal of Biological ChemistryFibroblast growth factor 2 (2,698 words) [view diff] exact match in snippet view article find links to article
of human basic fibroblast growth factor, a structural homolog of interleukin 1 beta". Proceedings of the National Academy of Sciences of the United StatesCLEC7A (1,690 words) [view diff] no match in snippet view article find links to article
regulation of protein-containing complex assembly positive regulation of interleukin-1 beta production positive regulation of cysteine-type endopeptidase activityJanus kinase 2 (3,166 words) [view diff] no match in snippet view article find links to article
growth hormone receptor signaling pathway positive regulation of interleukin-1 beta production positive regulation of DNA binding mesoderm developmentPyroptosis (3,948 words) [view diff] no match in snippet view article find links to article
1995). "Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme". Science. 267 (5206): 2000–3. Bibcode:1995Sci.Actin, cytoplasmic 2 (2,991 words) [view diff] exact match in snippet view article find links to article
"Actin, troponin C, Alzheimer amyloid precursor protein and pro-interleukin 1 beta as substrates of the protease from human immunodeficiency virus".Ferritin light chain (1,879 words) [view diff] no match in snippet view article find links to article
KR (July 1994). "Translational enhancement of H-ferritin mRNA by interleukin-1 beta acts through 5' leader sequences distinct from the iron responsiveYoon Bo-hyun (1,019 words) [view diff] no match in snippet view article find links to article
"Amniotic fluid cytokines (interleukin-6, tumor necrosis factor-alpha, interleukin-1 beta, and interleukin-8) and the risk for the development of bronchopulmonaryHsp27 (3,343 words) [view diff] no match in snippet view article find links to article
endothelial growth factor receptor signaling pathway positive regulation of interleukin-1 beta production vascular endothelial growth factor receptor signaling pathwayArrestin beta 2 (1,965 words) [view diff] no match in snippet view article find links to article
transport regulation of protein phosphorylation negative regulation of interleukin-1 beta production negative regulation of protein kinase B signaling negativeGranzyme A (1,629 words) [view diff] exact match in snippet view article find links to article
Proudfoot A, Solari R, Tschopp J (1995-05-01). "Granzyme A is an interleukin 1 beta-converting enzyme". The Journal of Experimental Medicine. 181 (5):CX3C motif chemokine receptor 1 (3,133 words) [view diff] no match in snippet view article find links to article
signaling central nervous system maturation negative regulation of interleukin-1 beta production social behavior autocrine signaling innate immune responseTNFAIP3 (1,971 words) [view diff] no match in snippet view article find links to article
regulation of endothelial cell apoptotic process negative regulation of interleukin-1 beta production negative regulation of smooth muscle cell proliferationPaul Ridker (1,664 words) [view diff] no match in snippet view article find links to article
inflammation inhibition with Canakinumab, a monoclonal antibody targeting interleukin-1-beta, can significantly reduce future risks of heart attack, need for expensiveInsulin-like growth factor 1 (4,575 words) [view diff] no match in snippet view article find links to article
associated smooth muscle cell apoptotic process negative regulation of interleukin-1 beta production negative regulation of tumor necrosis factor productionMothers against decapentaplegic homolog 3 (4,115 words) [view diff] no match in snippet view article find links to article
regulation of alkaline phosphatase activity positive regulation of interleukin-1 beta production pericardium development regulation of binding negativeGhrelin (4,801 words) [view diff] no match in snippet view article find links to article
positive regulation of adipose tissue development negative regulation of interleukin-1 beta production gastric emptying positive regulation of insulin secretionCaspase 3 (3,392 words) [view diff] no match in snippet view article find links to article
to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 beta-converting enzyme". The Journal of Biological Chemistry. 269 (49):Nancy Thornberry (1,718 words) [view diff] no match in snippet view article find links to article
(April 1992). "A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes". Nature. 356 (6372): 768–74. Bibcode:1992NaturNancy Thornberry (1,718 words) [view diff] no match in snippet view article find links to article
(April 1992). "A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes". Nature. 356 (6372): 768–74. Bibcode:1992NaturMaple syrup urine disease (5,497 words) [view diff] no match in snippet view article find links to article
are seen in IL-6 (interleukin-6), IL-10 (interleukin-10), IL-1beta (interleukin-1 beta), TNF-gamma (tumor necrosis factor-gamma), TNF-alpha (tumor necrosisProstaglandin EP4 receptor (4,808 words) [view diff] no match in snippet view article find links to article
mRNA through activation of p38 mitogen-activated protein kinase in interleukin-1 beta-treated human synovial fibroblasts". The Journal of Biological ChemistryINAVA (1,225 words) [view diff] no match in snippet view article find links to article
peptidoglycan response to muramyl dipeptide positive regulation of interleukin-1 beta production positive regulation of interleukin-10 production positiveISL1 (1,484 words) [view diff] no match in snippet view article find links to article
regulation of cell population proliferation positive regulation of interleukin-1 beta production positive regulation of interleukin-6 production positiveCaspase-9 (4,330 words) [view diff] no match in snippet view article find links to article
to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 beta-converting enzyme". The Journal of Biological Chemistry. 269 (49):Apoptosis (10,639 words) [view diff] exact match in snippet view article find links to article
Korsmeyer SJ (December 1996). "BAX-induced cell death may not require interleukin 1 beta-converting enzyme-like proteases". Proceedings of the National AcademyAIM2 (2,817 words) [view diff] no match in snippet view article find links to article
transcription factor activity immune response positive regulation of interleukin-1 beta production positive regulation of protein oligomerization activationAortic stenosis (6,878 words) [view diff] no match in snippet view article find links to article
lymphocytes), followed by the release of inflammatory mediators such as interleukin-1-beta and transforming growth factor beta-1 occurs. Subsequently, fibroblastsNF-κB (9,773 words) [view diff] no match in snippet view article find links to article
reactive oxygen species (ROS), tumor necrosis factor alpha (TNFα), interleukin 1-beta (IL-1β), bacterial lipopolysaccharides (LPS), isoproterenol, cocaineCyclooxygenase-3 (2,584 words) [view diff] no match in snippet view article find links to article
vasculature express cyclooxygenase-2 mRNA in response to systemic interleukin-1 beta: a possible site of prostaglandin synthesis responsible for fever"TREM2 (4,092 words) [view diff] no match in snippet view article find links to article
microglial cell activation response to ischemia negative regulation of interleukin-1 beta production negative regulation of tumor necrosis factor productionSUCNR1 (8,861 words) [view diff] no match in snippet view article find links to article
into blood stream macrophage activation involved in immune response interleukin-1 beta production glucose homeostasis positive regulation of inflammatoryCed-3 (2,147 words) [view diff] no match in snippet view article find links to article
elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme". Cell. 75 (4): 641–52. doi:10.1016/0092-8674(93)90485-9Lidia Rudnicka (2,946 words) [view diff] no match in snippet view article find links to article
Kähäri VM, Ledo I, Wu M, Rudnicka L, Uitto J: Human recombinant interleukin -1 beta up=regulates elastin gene expression in derma fibroblasts. EvidenceMSX-3 (896 words) [view diff] no match in snippet view article find links to article
"Effort-related motivational effects of the pro-inflammatory cytokine interleukin 1-beta: studies with the concurrent fixed ratio 5/ chow feeding choice task"Serpin (14,301 words) [view diff] no match in snippet view article find links to article
inhibition of inflammation: cowpox virus encodes an inhibitor of the interleukin-1 beta converting enzyme". Cell. 69 (4): 597–604. doi:10.1016/0092-8674(92)90223-YRoberto Paganelli (2,959 words) [view diff] no match in snippet view article find links to article
accompanying the aging process. In his assessment of factors impacting Interleukin-1 beta (IL-1β) serum levels within a sizable and diverse population, he determined