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searching for Cyclooxygenase-1 38 found (59 total)

Diproqualone (236 words) [view diff] exact match in snippet view article find links to article

antagonist activity at all histamine receptors, inhibition of the cyclooxygenase-1 enzyme, and possibly its agonist activity at both the sigma-1 receptor

Δ-Viniferin (650 words) [view diff] exact match in snippet view article find links to article

Delta-viniferin can also be produced from resveratrol by human PTGS1 (COX-1, cyclooxygenase-1) or from trans-resveratrol and (−)-epsilon-viniferin by horseradish

Ketorolac (2,684 words) [view diff] no match in snippet view article find links to article

of pregnancy or during breastfeeding. Ketorolac works by blocking cyclooxygenase 1 and 2 (COX1 and COX2), thereby decreasing production of prostaglandins

Arachidonate 5-lipoxygenase inhibitor (1,292 words) [view diff] exact match in snippet view article find links to article

Another important activity for hyperforin is a dual inhibitor of cyclooxygenase-1 and 5-lipoxygenase [59]. Moreover, this species attenuated the expression

Antileukotriene (1,015 words) [view diff] exact match in snippet view article find links to article

Another important activity for hyperforin is a dual inhibitor of cyclooxygenase-1 and 5-lipoxygenase [59]. Moreover, this species attenuated the expression

Mofezolac (507 words) [view diff] exact match in snippet view article find links to article

Cianciulli A, Salvatore R, Vitale P, et al. (2017). "Highly Selective Cyclooxygenase-1 Inhibitors P6 and Mofezolac Counteract Inflammatory State both In Vitro

Mechanism of action of aspirin (1,781 words) [view diff] exact match in snippet view article find links to article

I (March 2013). "Mechanism of the irreversible inhibition of human cyclooxygenase-1 by aspirin as predicted by QM/MM calculations". Journal of Molecular

Suicide inhibition (590 words) [view diff] no match in snippet view article find links to article

inhibits the acetaldehyde dehydrogenase enzyme. Aspirin, which inhibits cyclooxygenase 1 and 2 enzymes. Clavulanic acid, which inhibits β-lactamase: clavulanic

Ibuprofen (6,231 words) [view diff] exact match in snippet view article find links to article

Zheng X, Oda H, Harada S, Sugimoto Y, Sasaki K, et al. (April 2008). "Cyclooxygenase-1-selective inhibitors are attractive candidates for analgesics that

Mechanism of action (1,865 words) [view diff] exact match in snippet view article find links to article

Komaromi, I. (2013). "Mechanism of the irreversible inhibition of human cyclooxygenase-1 by aspirin as predicted by QM/MM calculations". Journal of Molecular

Antipyretic (1,185 words) [view diff] exact match in snippet view article find links to article

1542/peds.2010-3852. PMID 21357332. Cryer B, Feldman M (May 1998). "Cyclooxygenase-1 and cyclooxygenase-2 selectivity of widely used nonsteroidal anti-inflammatory

Cyclooxygenase-3 (2,584 words) [view diff] exact match in snippet view article find links to article

Evanson NK, Tomsik J, Elton TS, Simmons DL (October 2002). "COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic

Joy Ann Williams (505 words) [view diff] exact match in snippet view article find links to article

macrophage cytokine production by prostaglandin E₂: distinct roles of cyclooxygenase-1 and -2. As a graduate student, she worked at the National Cancer Institute

Furegrelate (1,892 words) [view diff] no match in snippet view article find links to article

metabolized to an endoperoxide called prostaglandin H2 by the enzyme cyclooxygenase 1. This endoperoxide is in turn metabolized to thromboxane A2 by thromboxane

Setipiprant (1,399 words) [view diff] no match in snippet view article find links to article

Setipiprant does not appreciably inhibit the activity of the enzyme cyclooxygenase 1 (COX-1), which is responsible for the synthesis of prostaglandins (including

Arachidonic acid (1,886 words) [view diff] exact match in snippet view article find links to article

Arachidonic acid is a precursor to a wide range of eicosanoids: The enzymes cyclooxygenase-1 and -2 (i.e. prostaglandin G/H synthase 1 and 2 [⁠PTGS1 and PTGS2])

Type II sensory fiber (652 words) [view diff] no match in snippet view article find links to article

of hyperpolarization-activated cyclic nucleotide gated channels via cyclooxygenase 1 cascade". Neuropharmacology. 113 (Pt A): 217–230. doi:10.1016/j.neuropharm

Prostacyclin (1,691 words) [view diff] exact match in snippet view article find links to article

Harrington LS, Leadbeater PD, Milne GL, Potter CM, et al. (October 2012). "Cyclooxygenase-1, not cyclooxygenase-2, is responsible for physiological production

Laminin, beta 1 (1,257 words) [view diff] exact match in snippet view article find links to article

subepithelial myofibroblasts express extracellular matrix proteins and cyclooxygenase-1 and -2". Am. J. Physiol. 273 (6 Pt 1): G1341–8. doi:10.1152/ajpgi.1997

Cāng zhú (1,453 words) [view diff] exact match in snippet view article find links to article

Steigel; Zhong-liang Chen; Rudolf Bauer (1998). "5-Lipoxygenase and cyclooxygenase-1 inhibitory active compounds from Atractylodes lancea". J. Nat. Prod

PTGES3 (969 words) [view diff] exact match in snippet view article find links to article

cytosolic prostaglandin E2 synthase that is functionally coupled with cyclooxygenase-1 in immediate prostaglandin E2 biosynthesis". J. Biol. Chem. 275 (42):

Indometacin (2,258 words) [view diff] exact match in snippet view article find links to article

those of all other NSAIDs. For instance, indometacin inhibits both cyclooxygenase-1 and cyclooxygenase-2, which then inhibits the production of prostaglandins

Postherpetic neuralgia (2,910 words) [view diff] exact match in snippet view article find links to article

activated sodium channel (VGSC) blockade (funapide and lidocaine), cyclooxygenase-1 (COX-1) inhibition (TRK-700), adapter-associated kinase 1 inhibition

Endothelium-derived hyperpolarizing factor (1,377 words) [view diff] exact match in snippet view article find links to article

that lack both endothelial nitric oxide synthase (eNOS) and COX-1 (Cyclooxygenase-1, a protein that acts as an enzyme to speed up the production of certain

Peptic ulcer disease (5,882 words) [view diff] no match in snippet view article find links to article

stimulated by certain prostaglandins. NSAIDs block the function of cyclooxygenase 1 (COX-1), which is essential for the production of these prostaglandins

Glutathione peroxidase 4 (2,412 words) [view diff] no match in snippet view article find links to article

peroxidase up-regulates arachidonate metabolism by 12S-lipoxygenase and cyclooxygenase 1 in human epidermoid carcinoma A431 cells". FASEB Journal. 17 (12):

Cyclooxygenase-2 (3,662 words) [view diff] no match in snippet view article find links to article

at Brigham Young University. Arachidonic acid Cyclooxygenase Cyclooxygenase 1 NSAID Discovery and development of COX-2 selective inhibitors COX-2

Glucocorticoid (5,542 words) [view diff] exact match in snippet view article find links to article

Chen Z, Pace MC, Shaul PW (Feb 1999). "Glucocorticoids downregulate cyclooxygenase-1 gene expression and prostacyclin synthesis in fetal pulmonary artery

Diclofenac (5,373 words) [view diff] exact match in snippet view article find links to article

1016/0002-9343(86)90077-x. PMID 3085490. Cryer B, Feldman M (May 1998). "Cyclooxygenase-1 and cyclooxygenase-2 selectivity of widely used nonsteroidal anti-inflammatory

Uterotonic (2,321 words) [view diff] exact match in snippet view article find links to article

membrane phospholipids and is eventually converted to prostaglandins by cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2). Due to this mechanism, prostaglandins

Platelet (8,530 words) [view diff] exact match in snippet view article find links to article

(NSAIDS). Aspirin irreversibly disrupts platelet function by inhibiting cyclooxygenase-1 (COX1), and hence normal hemostasis. The resulting platelets are unable

Nonsteroidal anti-inflammatory drug (11,497 words) [view diff] exact match in snippet view article find links to article

inhibitors of the cyclooxygenase (COX) enzymes, inhibiting both the cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) isoenzymes. This inhibition is

Aspirin-exacerbated respiratory disease (5,530 words) [view diff] exact match in snippet view article find links to article

NSAIDs such as ibuprofen, and to any medication that inhibits the cyclooxygenase-1 (COX-1) enzyme, although paracetamol (acetaminophen) in low doses is

Arachidonate 5-lipoxygenase (7,553 words) [view diff] exact match in snippet view article find links to article

Steinhilber D, Werz O (Dec 2002). "Hyperforin is a dual inhibitor of cyclooxygenase-1 and 5-lipoxygenase". Biochemical Pharmacology. 64 (12): 1767–1775.

Free statistical software (3,299 words) [view diff] exact match in snippet view article find links to article

Bosetti, Francesca (2007). "Differential gene expression patterns in cyclooxygenase-1 and cyclooxygenase-2 deficient mouse brain". Genome Biol. 8 (1): R14

Depressant (12,985 words) [view diff] exact match in snippet view article find links to article

antagonist activity at all histamine receptors, inhibition of the cyclooxygenase-1 enzyme, and possibly its agonist activity at both the Sigma-1 receptor

Discovery and development of cyclooxygenase 2 inhibitors (4,471 words) [view diff] no match in snippet view article find links to article

using selective COX-2 inhibitors. Arachidonic acid Cyclooxygenase Cyclooxygenase 1 Cyclooxygenase 2 NSAID COX-2 selective inhibitor Marnett, L. J.; Kalgutkar

Lysine acetylsalicylate (2,797 words) [view diff] exact match in snippet view article find links to article

I (March 2013). "Mechanism of the irreversible inhibition of human cyclooxygenase-1 by aspirin as predicted by QM/MM calculations". Journal of Molecular