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searching for TREM2 16 found (37 total)

alternate case: tREM2

Immunoreceptor tyrosine-based activation motif (1,268 words) [view diff] exact match in snippet view article find links to article

Lanier, Lewis L.; Seaman, William E.; Nakamura, Mary C. (February 2006). "TREM2, a DAP12-associated receptor, regulates osteoclast differentiation and function"

Rudolph E. Tanzi (4,371 words) [view diff] exact match in snippet view article find links to article

innate immune gene, TREM2. Knockout of CD33 in AD mice attenuated amyloid-beta pathology and improved cognition while knockout of TREM2 led to opposite effects

James Adjaye (938 words) [view diff] exact match in snippet view article find links to article

Lymphoblast-derived integration-free iPSC line AD-TREM2-3 from a 74 year-old Alzheimer's disease patient expressing the TREM2 p.R47H variant., 2018; (contrib.) Modeling

Sam Gandy (1,355 words) [view diff] exact match in snippet view article find links to article

Samuel; Noggle, Scott. "Use of iPSC systems to define roles of microglial TREM2/DAP12 and CR3/DAP12 complexes and their genetic variants in specifying risk

David M. Holtzman (2,235 words) [view diff] exact match in snippet view article find links to article

Koscal LJ, Jiang H, Manis M, Colonna M, Lee VMY, Ulrich JD, Holtzman DM. TREM2 function impedes tau seeding in neuritic plaques. Nat Neurosci. 2019 Aug;22(8):1217-1222

Miriam Merad (2,046 words) [view diff] exact match in snippet view article find links to article

advances from the Merad team in this area include the identification of TREM2 tumor macrophages as immunosuppressive cells that limit natural killer cell

Alison Goate (2,373 words) [view diff] exact match in snippet view article find links to article

dependence." Am J Psychiatry PMCID: PMC2574742 Guerreiro R et al.; (2013) "TREM2 Variants in Alzheimer's Disease" NEJM PMCID: PMC3631573. Cruchaga C. et

Alzheimer's Research UK (1,426 words) [view diff] exact match in snippet view article find links to article

studied data from more than 25,000 people to link a rare variant of the TREM2 gene – which is known to play a role in the immune system – to a higher

Buddy Miller (2,644 words) [view diff] case mismatch in snippet view article find links to article

he often uses a Swart Atomic Space Tones amplifier and a Fulltone Supa-Trem2 pedal. He mostly records using Pro Tools, but in his recording studio Buddy

Reinhard Heun (1,559 words) [view diff] exact match in snippet view article find links to article

... & Daniilidou, M. (2017). Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. Nature

Janus kinase 3 (5,166 words) [view diff] exact match in snippet view article find links to article

deficiency is responsible for Jak3 deficiency in the brain, reduced microglial TREM2 expression, microglial activation and compromised clearance of Aβ and pTau

Albert Hofman (epidemiologist) (1,209 words) [view diff] exact match in snippet view article

N Engl J Med. 2013 Oct 17;369(16):1529-36. Jonsson T, et al. Variant of TREM2 Associated with the Risk of Alzheimer's Disease. N Engl J Med. 2013;368:107-116

Michal Schwartz (2,126 words) [view diff] exact match in snippet view article find links to article

disease modification mediated by bone marrow-derived macrophages via a TREM2-independent pathway in mouse model of amyloidosis". Nature Aging. 2 (1):

Tobacco smoking (14,445 words) [view diff] exact match in snippet view article find links to article

parenchyma; the expression levels of a panel of seven genes (KMO, CD1A, SPINK5, TREM2, CYBB, DNASE2B, FGG) are increased in the lung tissue of smokers. Passive

PLD3 (2,967 words) [view diff] exact match in snippet view article find links to article

S2CID 52869488. Jiao B, Liu X, Tang B, et al. (October 2014). "Investigation of TREM2, PLD3, and UNC5C variants in patients with Alzheimer's disease from mainland

2012 in science (38,776 words) [view diff] exact match in snippet view article find links to article

2012-11-12. Retrieved 2023-07-02. Guerreiro, Rita; et al. (2013-01-10). "TREM2 Variants in Alzheimer's Disease". New England Journal of Medicine. 368 (2)