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Longer titles found: Apoptotic DNA fragmentation (view)

searching for DNA fragmentation 93 found (133 total)

alternate case: dNA fragmentation

DFFA (1,403 words) [view diff] exact match in snippet view article find links to article

DNA fragmentation factor subunit alpha (DFFA), also known as Inhibitor of caspase-activated DNase (ICAD), is a protein that in humans is encoded by the
Caspase-activated DNase (3,073 words) [view diff] exact match in snippet view article find links to article
Caspase-activated DNase (CAD) or DNA fragmentation factor subunit beta is a protein that in humans is encoded by the DFFB gene. It breaks up the DNA during
Fragmentation (cell biology) (1,713 words) [view diff] exact match in snippet view article
irregularities such as red blood cell fragmentation and sperm cell DNA fragmentation. DNA cloning can be performed spontaneously by the cell for reproductive
Aneugen (575 words) [view diff] exact match in snippet view article find links to article
(Xia et al., 2004). Exposure of male workers to carbaryl increased DNA fragmentation in spermatozoa, and also increased sex chromosome disomy by 1.7-fold
Deoxyribonuclease I (1,382 words) [view diff] exact match in snippet view article find links to article
been suggested to be one of the deoxyribonucleases responsible for DNA fragmentation during apoptosis. DNase I binds to the cytoskeletal protein actin
CIDEA (741 words) [view diff] exact match in snippet view article find links to article
activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional
Restriction digest (860 words) [view diff] exact match in snippet view article find links to article
prepare DNA for analysis or other processing. It is sometimes termed DNA fragmentation (this term is used for other procedures as well). Hartl and Jones
Pseudoapoptosis (845 words) [view diff] exact match in snippet view article find links to article
extent to which DNA fragmentation occurs. In the presence of large BLM concentrations, pseudoapoptosis is observed as rapid DNA fragmentation occurs, resulting
API5 (770 words) [view diff] exact match in snippet view article find links to article
negatively regulates acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of chemotherapeutic drugs
TMEM123 (689 words) [view diff] exact match in snippet view article find links to article
and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor
CIDEB (697 words) [view diff] exact match in snippet view article find links to article
cell death activators with homology to the 45 kDa subunit of the DNA fragmentation factor". EMBO J. 17 (9): 2526–33. doi:10.1093/emboj/17.9.2526. PMC 1170594
DNASE1L3 (724 words) [view diff] exact match in snippet view article find links to article
endonuclease DNAS1L3 is required for etoposide-induced internucleosomal DNA fragmentation and increases etoposide cytotoxicity in transfected osteosarcoma cells"
DRIP-seq (1,972 words) [view diff] no match in snippet view article find links to article
DRIP-seq (DRIP-sequencing) is a technology for genome-wide profiling of a type of DNA-RNA hybrid called an "R-loop". DRIP-seq utilizes a sequence-independent
Parthanatos (3,623 words) [view diff] exact match in snippet view article find links to article
factor (AIF) from the mitochondria to the nucleus where it induces DNA fragmentation and ultimately cell death. This general pathway has been outlined
Marc Goldstein (1,304 words) [view diff] exact match in snippet view article find links to article
focuses on the relationship between high sperm DNA fragmentation and varicocele, mapping sperm DNA fragmentation in the male genital tract to determine the
DUT (gene) (1,937 words) [view diff] exact match in snippet view article
removal and reincorporation of dUTP, is self-defeating and leads to DNA fragmentation and cell death. Alternative splicing of this gene leads to different
Betulinic acid (1,827 words) [view diff] exact match in snippet view article find links to article
accompanied by caspase activation, mitochondrial membrane alterations and DNA fragmentation. Caspases are produced as inactive proenzymes, which are proteolytically
Seminiferous tubule (358 words) [view diff] exact match in snippet view article find links to article
S, Sabanegh E, Agarwal A (2010). "Semen characteristics and sperm DNA fragmentation in infertile men with low and high levels of seminal reactive oxygen
Oropouche orthobunyavirus (559 words) [view diff] exact match in snippet view article find links to article
induced by the virus. It was found that OROV causes apoptosis by DNA fragmentation. In UV-inactivated OROV, virus-receptor binding was not enough and
Staphylococcus aureus alpha toxin (791 words) [view diff] exact match in snippet view article find links to article
pores. This pore allows the exchange of monovalent ions, resulting in DNA fragmentation and eventually apoptosis. Higher concentrations result in the toxin
Supraorganization (114 words) [view diff] exact match in snippet view article find links to article
Vidal, BC; Mello, ML (February 2005). "Chromatin supraorganization, DNA fragmentation, and cell death in snake erythrocytes". Biochem Cell Biol. 83 (1):
Ischemic cell death (1,093 words) [view diff] exact match in snippet view article find links to article
mediated by caspase activation, particularly caspase-3. Oligonuclosomal DNA fragmentation is initiated by caspase-activated deoxyribonuclease following caspase-3
ENDOG (2,404 words) [view diff] exact match in snippet view article find links to article
has also been implicated in Parkinson’s disease (PD), as it induces DNA fragmentation in neurons when translocated from the mitochondria to nuclei. This
Cell death (1,502 words) [view diff] exact match in snippet view article find links to article
shrinkage, nuclear fragmentation, chromatin condensation, and chromosomal DNA fragmentation. It is now thought that – in a developmental context – cells are induced
List of MeSH codes (G05) (865 words) [view diff] case mismatch in snippet view article
telophase MeSH G05.180.099 – chromosome breakage MeSH G05.180.185 – dna fragmentation MeSH G05.192.095 – chromatin assembly and disassembly MeSH G05.195
Mir-145 (1,757 words) [view diff] exact match in snippet view article find links to article
Ge S, Ji H, Hu X, Chen W (2010). "MiR-145, a new regulator of the DNA fragmentation factor-45 (DFF45)-mediated apoptotic network". Molecular Cancer. 9:
Restriction fragment length polymorphism (1,102 words) [view diff] exact match in snippet view article find links to article
amount of sample DNA, and the combined process of probe labeling, DNA fragmentation, electrophoresis, blotting, hybridization, washing, and autoradiography
Hydroxycitric acid (773 words) [view diff] exact match in snippet view article find links to article
extract on body weight, hepatic and testicular lipid peroxidation, DNA fragmentation and histopathological data over a period of 90 days". Mol. Cell. Biochem
HMGB2 (1,181 words) [view diff] exact match in snippet view article find links to article
production • nucleosome assembly • DNA recombination • apoptotic DNA fragmentation • male gonad development • regulation of transcription, DNA-templated
ACIN1 (635 words) [view diff] exact match in snippet view article find links to article
Schulze-Osthoff K, Schwerk C (2006). "Loss of Acinus inhibits oligonucleosomal DNA fragmentation but not chromatin condensation during apoptosis". J. Biol. Chem. 281
Caspase 3 (3,351 words) [view diff] exact match in snippet view article find links to article
apoptosis, where it is responsible for chromatin condensation and DNA fragmentation. Elevated levels of a fragment of Caspase-3, p17, in the bloodstream
Chromosome abnormality (1,580 words) [view diff] exact match in snippet view article find links to article
Gori M, Orvieto R, Piomboni P (2014). "Chromosomal aneuploidies and DNA fragmentation of human spermatozoa from patients exposed to perfluorinated compounds"
Eosinophil cationic protein (2,267 words) [view diff] exact match in snippet view article find links to article
in chromatin condensation, sub-G1 population, PARP cleavage, and DNA fragmentation indicate that ECP induces apoptosis in human bronchial epithelial
GZMM (533 words) [view diff] exact match in snippet view article find links to article
inhibitor of caspase-activated DNase (CAD) to unleash CAD leading to DNA fragmentation". J. Immunol. 177 (2): 1171–8. doi:10.4049/jimmunol.177.2.1171. PMID 16818775
Dinophysis (2,522 words) [view diff] exact match in snippet view article find links to article
A.M. (October 2014). "Does the marine biotoxin okadaic acid cause DNA fragmentation in the blue mussel and the pacific oyster?". Marine Environmental
Sperm washing (714 words) [view diff] exact match in snippet view article find links to article
Jurisicova A, Casper RF (September 2001). "Sperm swim-up techniques and DNA fragmentation". Hum. Reprod. 16 (9): 1950–3. doi:10.1093/humrep/16.9.1950. PMID 11527903
Liquid biopsy (1,187 words) [view diff] exact match in snippet view article find links to article
Watts C, Brindle KM, Rosenfeld N (2018). "Detection of cell-free DNA fragmentation and copy number alterations in cerebrospinal fluid from glioma patients"
FOXL2 (2,187 words) [view diff] exact match in snippet view article find links to article
bridge • nucleoplasm Biological process • oocyte growth • apoptotic DNA fragmentation • regulation of transcription, DNA-templated • extraocular skeletal
Deoxyribonuclease ii, lysosomal (187 words) [view diff] exact match in snippet view article find links to article
process • DNA catabolic process, endonucleolytic • apoptotic process • apoptotic DNA fragmentation • regulation of immune response Sources:Amigo / QuickGO
APAF1 (1,588 words) [view diff] exact match in snippet view article find links to article
signaling pathway • forebrain development • regulation of apoptotic DNA fragmentation • protein homooligomerization • activation of cysteine-type endopeptidase
CTL-mediated cytotoxicity (410 words) [view diff] exact match in snippet view article find links to article
activation, which is similar to granzyme B. This ultimately leads to DNA fragmentation. Kindt, Thomas, Richard Goldsby, Barbara Osborne, and Janis Kuby.
PLSCR1 (1,138 words) [view diff] no match in snippet view article find links to article
resolution of phospholipid scramblase 1 (PLSCR1), caspase-3 activation and DNA-fragmentation in the human hippocampus after cerebral ischemia". Neurochem. Int
Ashok Agarwal (5,035 words) [view diff] exact match in snippet view article find links to article
SC; Ko, E; Ramasamy, R; Zini, A (2016). "Clinical utility of sperm DNA fragmentation testing: practice recommendations based on clinical scenarios". Transl
Flap structure-specific endonuclease 1 (2,440 words) [view diff] exact match in snippet view article find links to article
via semi-conservative replication • base-excision repair • apoptotic DNA fragmentation • retina development in camera-type eye Sources:Amigo / QuickGO
Karyopherin alpha 1 (1,126 words) [view diff] exact match in snippet view article find links to article
recombination • GO:0046795 intracellular transport of virus • apoptotic DNA fragmentation • protein import into nucleus • protein transport • modulation by
HSF1 (2,411 words) [view diff] exact match in snippet view article find links to article
regulation of inclusion body assembly • positive regulation of apoptotic DNA fragmentation • cellular response to L-glutamine • response to psychosocial stress
TIA1 (1,262 words) [view diff] exact match in snippet view article find links to article
as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein
Hydroxylation of estradiol (1,761 words) [view diff] exact match in snippet view article find links to article
via induction of caspase-8, followed by caspase-3 and eventually DNA fragmentation. Induction of apoptosis by 2-meOE2 may be p53 dependent or independent
Hemolysin (2,656 words) [view diff] exact match in snippet view article find links to article
since it allows the exchange of monovalent ions that would cause the DNA fragmentation. Some hemolysins damage the erythrocyte membrane by cleaving the phospholipids
Granzyme B (1,915 words) [view diff] exact match in snippet view article find links to article
release from the mitochondria. Granzyme B can cleave ICAD leading to DNA fragmentation and the laddering pattern associated with apoptosis. Granzyme B has
Chromosome (6,291 words) [view diff] exact match in snippet view article find links to article
Orvieto R, Piomboni P (November 2015). "Chromosomal aneuploidies and DNA fragmentation of human spermatozoa from patients exposed to perfluorinated compounds"
NMNAT1 (1,228 words) [view diff] exact match in snippet view article find links to article
regulation of neuron apoptotic process • negative regulation of apoptotic DNA fragmentation • nucleotide biosynthetic process Sources:Amigo / QuickGO
HMGB1 (3,069 words) [view diff] exact match in snippet view article find links to article
complex Biological process • T-helper 1 cell activation • apoptotic DNA fragmentation • adaptive immune response • regulation of transcription by RNA polymerase
Dicer (3,128 words) [view diff] exact match in snippet view article find links to article
involved in RNA interference • gene silencing by RNA • apoptotic DNA fragmentation • negative regulation of tumor necrosis factor production • NIK/NF-kappaB
Bcl-2-associated X protein (2,112 words) [view diff] exact match in snippet view article find links to article
morphogenesis • leukocyte homeostasis • positive regulation of apoptotic DNA fragmentation • mitochondrial fragmentation involved in apoptotic process • positive
Steroidogenic factor 1 (3,472 words) [view diff] exact match in snippet view article find links to article
maintaining elevated ACTH levels. Observed morphological changes and DNA fragmentation was consistent with apoptosis and structural regression resulting
AIFM1 (1,527 words) [view diff] exact match in snippet view article find links to article
regulation of neuron apoptotic process • regulation of apoptotic DNA fragmentation • cellular response to hydrogen peroxide • intrinsic apoptotic signaling
Deoxyribonuclease 2 beta (396 words) [view diff] exact match in snippet view article find links to article
region • lysosome • intracellular anatomical structure Biological process • DNA metabolic process • apoptotic DNA fragmentation Sources:Amigo / QuickGO
PAM16 (698 words) [view diff] exact match in snippet view article find links to article
process • negative regulation of release of cytochrome c from mitochondria • negative regulation of apoptotic DNA fragmentation Sources:Amigo / QuickGO
KPNB1 (1,907 words) [view diff] exact match in snippet view article find links to article
process • GO:0046795 intracellular transport of virus • apoptotic DNA fragmentation • Ran protein signal transduction • establishment of protein localization
Capacitation (2,031 words) [view diff] exact match in snippet view article find links to article
is the most suitable method to improve fertilization and to reduce DNA fragmentation positive spermatozoa of infertile men". Anatolian Journal of Obstetrics
Pyroptosis (3,656 words) [view diff] exact match in snippet view article find links to article
NO YES YES Pore formation NO YES YES Membrane blebbing YES YES NO DNA fragmentation YES YES YES Nucleus intact NO YES NO Mechanism Caspase-1 activation
Paleogenomics (2,594 words) [view diff] exact match in snippet view article find links to article
(HTS) to identify depurination (a process that drives post-mortem DNA fragmentation, younger samples present more adenine than guanine), single strand
H2AFX (2,601 words) [view diff] exact match in snippet view article find links to article
Nieves-Neira W, Boon C, Pommier Y, Bonner WM (Mar 2000). "Initiation of DNA fragmentation during apoptosis induces phosphorylation of H2AX histone at serine
KCNB1 (3,743 words) [view diff] exact match in snippet view article find links to article
surge of KCNB1 current induces activation of a pro-apoptotic pathway, DNA fragmentation, and caspase activation. Another proposed mechanism for regulation
Fumonisin B1 (3,188 words) [view diff] exact match in snippet view article find links to article
synthase is not responsible for this effect. The main factors could be DNA fragmentation and caspase-3 activation. FB1 has also immunotoxic effects, but much
Ceramide kinase (1,800 words) [view diff] exact match in snippet view article find links to article
apoptosis by inhibiting the caspase-9/caspase-3 pathway and preventing DNA fragmentation in macrophages. This is thought to occur via C-1-P interacting with
Douglas R. Green (901 words) [view diff] exact match in snippet view article find links to article
in T cell hybridomas is due to apoptosis. Morphologic aspects and DNA fragmentation". Journal of Immunology. 144 (9): 3326–33. PMID 1691753. Shi, Y; Glynn
Superoxide dismutase (5,110 words) [view diff] exact match in snippet view article find links to article
(February 2014). "Absence of superoxide dismutase activity causes nuclear DNA fragmentation during the aging process" (PDF). Biochem. Biophys. Res. Commun. 444
Citrinin (3,831 words) [view diff] exact match in snippet view article find links to article
apoptosis and not necrosis as CTN exposure led to an increase of nuclear DNA fragmentation or breakdown of chromatin, which are both characteristics of apoptosis
Adenosine A2A receptor (4,866 words) [view diff] exact match in snippet view article find links to article
PMC 3427751. PMID 7775460. Szondy Z (December 1994). "Adenosine stimulates DNA fragmentation in human thymocytes by Ca(2+)-mediated mechanisms". The Biochemical
Self-incompatibility (4,215 words) [view diff] exact match in snippet view article find links to article
F. C. H. Franklin, and V. E. Franklin-Tong (2000). "Evidence for DNA fragmentation triggered in the selfincompatibility response in pollen of Papaver
P16 (4,171 words) [view diff] exact match in snippet view article find links to article
activity involved in apoptotic process • regulation of apoptotic DNA fragmentation • positive regulation of transcription by RNA polymerase II • positive
Intracytoplasmic morphologically selected sperm injection (651 words) [view diff] exact match in snippet view article find links to article
40-70% of the head. Cases where IMSI may be used: High levels of DNA fragmentation. High levels of sperm aneuploidy. Men with severe oligozoospermia
TPEN (1,094 words) [view diff] exact match in snippet view article find links to article
When these T lymphocytes were pretreated with caspase inhibitors, DNA fragmentation (an indicator of apoptosis) was prevented. This suggests that apoptosis
Ranjith Ramasamy (956 words) [view diff] exact match in snippet view article find links to article
to Miller School of Medicine students. "Clinical utility of sperm DNA fragmentation testing: practice recommendations based on clinical scenarios", A
Benzodiazepine (16,059 words) [view diff] exact match in snippet view article find links to article
Finollo R, Ledda A, Brambilla G (January 1989). "Absence of liver DNA fragmentation in rats treated with high oral doses of 32 benzodiazepine drugs".
List of MeSH codes (G04) (2,119 words) [view diff] case mismatch in snippet view article
apoptosis MeSH G04.335.139.160.060 – anoikis MeSH G04.335.139.160.200 – dna fragmentation MeSH G04.335.139.399 – autophagy MeSH G04.335.139.638 – necrosis MeSH
Entosis (1,114 words) [view diff] exact match in snippet view article find links to article
escape from host cell. In clinical cancer specimens, evidence of DNA fragmentation has been found suggesting that non-apoptotic cell death may be a common
CDKN2A (3,319 words) [view diff] exact match in snippet view article find links to article
activity involved in apoptotic process • regulation of apoptotic DNA fragmentation • positive regulation of transcription by RNA polymerase II • positive
O-Toluidine (2,779 words) [view diff] exact match in snippet view article find links to article
Corbu, C.; Brambilla, G. (2002). "Correlation between induction of DNA fragmentation in urinary bladder cells from rats and humans and tissue-specific
Mechanism of anoxic depolarization in the brain (2,374 words) [view diff] exact match in snippet view article find links to article
lipolysis, proteolysis, cell swelling, microtubule disaggregation, and DNA fragmentation. Neurons are more susceptible to brain ischemia than the supporting
T helper cell (7,367 words) [view diff] exact match in snippet view article find links to article
apoptose virus-infected cells and to induce host as well as viral DNA fragmentation. IFN alpha/beta can suppress transcription to avoid virus replication
Inflammasome (5,779 words) [view diff] exact match in snippet view article find links to article
natural killer cell activation, cleavage and inactivation of IL-33, DNA fragmentation and cell pore formation, inhibition of glycolytic enzymes, activation
HPG80 (4,995 words) [view diff] exact match in snippet view article find links to article
significant loss of caspase 9 and caspase 3 activation and a decrease in DNA fragmentation. Therefore, the effect of hPG80 on cell survival results from both
Mega-telomere (2,158 words) [view diff] exact match in snippet view article find links to article
individual variability. Slot blot, however, is conducted without DNA fragmentation or separation, rather whole genomic DNA is used to quantify the total
Actin (20,848 words) [view diff] exact match in snippet view article find links to article
inhibitors, but not caspase inhibitors, prevent actin proteolysis and DNA fragmentation during apoptosis". Journal of Cell Science. 111 (Pt 6): 713–722. PMID 9472000
Withaferin A (3,398 words) [view diff] exact match in snippet view article find links to article
release of cytochrome c and activation of caspase-likeprotease and DNA fragmentation, finally leading to apoptosis. Animal and in vitro studies have shown
Cell-Cycle Hypothesis of Alzheimer's Disease (1,667 words) [view diff] exact match in snippet view article find links to article
has still been proven although the presence of apoptotic bodies, DNA fragmentation, granulated and marginated chromatin and shrunken and irregular cell
Valina L. Dawson (3,384 words) [view diff] exact match in snippet view article find links to article
the nucleus where the nuclease activity of MIF leads to large scale DNA fragmentation. To distinguish this form of cell death from other cell death signaling
Obesity and fertility (5,886 words) [view diff] exact match in snippet view article find links to article
associated with a reduction in sperm motility, an increase in sperm DNA fragmentation, and increased sperm oxidative stress. Sleep apnea is defined as a
John Aitken (biologist) (3,342 words) [view diff] exact match in snippet view article
and functional integrity of human spermatozoa: lipid peroxidation, DNA fragmentation and effectiveness of antioxidants". Human Reproduction. 13 (6): 1429–36
Safety of electronic cigarettes (36,427 words) [view diff] exact match in snippet view article find links to article
of OxPhos electron transport chain (ETC) complex IV subunit) and DNA fragmentation in lung fibroblasts." A 2013 review found metallic and nanoparticles