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Longer titles found: Apoptotic DNA fragmentation (view)

searching for DNA fragmentation 106 found (149 total)

DFFA (1,405 words) [view diff] exact match in snippet view article find links to article

DNA fragmentation factor subunit alpha (DFFA), also known as Inhibitor of caspase-activated DNase (ICAD), is a protein that in humans is encoded by the

Spermatid (594 words) [view diff] exact match in snippet view article find links to article

breaks persist in mature sperm, the result can be increased sperm DNA fragmentation which is associated with impaired fertility and an increased incidence

Caspase-activated DNase (3,047 words) [view diff] exact match in snippet view article find links to article

Caspase-activated DNase (CAD) or DNA fragmentation factor subunit beta is a protein that in humans is encoded by the DFFB gene. It breaks up the DNA during

Fragmentation (cell biology) (1,724 words) [view diff] exact match in snippet view article

irregularities such as red blood cell fragmentation and sperm cell DNA fragmentation. DNA cloning can be performed spontaneously by the cell for reproductive

Aneugen (659 words) [view diff] exact match in snippet view article find links to article

(Xia et al., 2004). Exposure of male workers to carbaryl increased DNA fragmentation in spermatozoa, and also increased sex chromosome disomy by 1.7-fold

Deoxyribonuclease I (1,397 words) [view diff] exact match in snippet view article find links to article

been suggested to be one of the deoxyribonucleases responsible for DNA fragmentation during apoptosis. DNase I binds to the cytoskeletal protein actin

Restriction digest (784 words) [view diff] exact match in snippet view article find links to article

prepare DNA for analysis or other processing. It is sometimes termed DNA fragmentation, though this term is used for other procedures as well. In a restriction

CIDEA (744 words) [view diff] exact match in snippet view article find links to article

activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional

Pseudoapoptosis (845 words) [view diff] exact match in snippet view article find links to article

extent to which DNA fragmentation occurs. In the presence of large BLM concentrations, pseudoapoptosis is observed as rapid DNA fragmentation occurs, resulting

API5 (770 words) [view diff] exact match in snippet view article find links to article

negatively regulates acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of chemotherapeutic drugs

TMEM123 (704 words) [view diff] exact match in snippet view article find links to article

and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor

CIDEB (895 words) [view diff] case mismatch in snippet view article find links to article

Zhou L (2016-02-26). "Differential Roles of Cell Death-inducing DNA Fragmentation Factor-α-like Effector (CIDE) Proteins in Promoting Lipid Droplet

Caspase-2 (1,012 words) [view diff] exact match in snippet view article find links to article

substrates, triggering the distinct features of apoptosis, such as DNA fragmentation, chromatin condensation, and plasma membrane blebbing. Caspase-2,

DRIP-seq (1,997 words) [view diff] no match in snippet view article find links to article

DRIP-seq (DRIP-sequencing) is a technology for genome-wide profiling of a type of DNA-RNA hybrid called an "R-loop". DRIP-seq utilizes a sequence-independent

Seminiferous tubule (345 words) [view diff] exact match in snippet view article find links to article

S, Sabanegh E, Agarwal A (2010). "Semen characteristics and sperm DNA fragmentation in infertile men with low and high levels of seminal reactive oxygen

Marc Goldstein (1,280 words) [view diff] exact match in snippet view article find links to article

focuses on the relationship between high sperm DNA fragmentation and varicocele, mapping sperm DNA fragmentation in the male genital tract to determine the

Betulinic acid (1,916 words) [view diff] exact match in snippet view article find links to article

accompanied by caspase activation, mitochondrial membrane alterations and DNA fragmentation. Caspases are produced as inactive proenzymes, which are proteolytically

Parthanatos (3,633 words) [view diff] exact match in snippet view article find links to article

factor (AIF) from the mitochondria to the nucleus where it induces DNA fragmentation and ultimately cell death. This general pathway has been outlined

DUT (gene) (1,955 words) [view diff] exact match in snippet view article

removal and reincorporation of dUTP, is self-defeating and leads to DNA fragmentation and cell death. Alternative splicing of this gene leads to different

Supraorganization (115 words) [view diff] exact match in snippet view article find links to article

Vidal, BC; Mello, ML (February 2005). "Chromatin supraorganization, DNA fragmentation, and cell death in snake erythrocytes". Biochem Cell Biol. 83 (1):

Ischemic cell death (1,082 words) [view diff] exact match in snippet view article find links to article

mediated by caspase activation, particularly caspase-3. Oligonuclosomal DNA fragmentation is initiated by caspase-activated deoxyribonuclease following caspase-3

Staphylococcus aureus alpha toxin (802 words) [view diff] exact match in snippet view article find links to article

pores. This pore allows the exchange of monovalent ions, resulting in DNA fragmentation and eventually apoptosis. Higher concentrations result in the toxin

ENDOG (2,404 words) [view diff] exact match in snippet view article find links to article

has also been implicated in Parkinson's disease (PD), as it induces DNA fragmentation in neurons when translocated from the mitochondria to nuclei. This

Karyorrhexis (1,555 words) [view diff] case mismatch in snippet view article find links to article

PMC 7184752. PMID 32351716. Nagata, Shigekazu (2000-04-10). "Apoptotic DNA Fragmentation". Experimental Cell Research. 256 (1): 12–18. doi:10.1006/excr.2000

Reproductive success (3,543 words) [view diff] exact match in snippet view article find links to article

with a high prevalence of sperm DNA damage as measured by DNA fragmentation. DNA fragmentation was also found to be inversely correlated with sperm motility

Testicular atrophy (2,820 words) [view diff] exact match in snippet view article find links to article

oxidative stress in the semen, there may also be higher levels of sperm DNA fragmentation for people with varicoceles. In some cases, people with testicular

Oropouche orthobunyavirus (1,060 words) [view diff] exact match in snippet view article find links to article

it induces apoptosis. It was found that OROV causes apoptosis by DNA fragmentation. In UV-inactivated OROV, virus-receptor binding was not enough and

Mir-145 (1,481 words) [view diff] exact match in snippet view article find links to article

J, Guo H, Qian G, et al. (2010). "MiR-145, a new regulator of the DNA fragmentation factor-45 (DFF45)-mediated apoptotic network". Molecular Cancer. 9:

List of MeSH codes (G05) (865 words) [view diff] case mismatch in snippet view article

telophase MeSH G05.180.099 – chromosome breakage MeSH G05.180.185 – dna fragmentation MeSH G05.192.095 – chromatin assembly and disassembly MeSH G05.195

Hydroxycitric acid (772 words) [view diff] exact match in snippet view article find links to article

extract on body weight, hepatic and testicular lipid peroxidation, DNA fragmentation and histopathological data over a period of 90 days". Mol. Cell. Biochem

Restriction fragment length polymorphism (1,164 words) [view diff] exact match in snippet view article find links to article

amount of sample DNA, and the combined process of probe labeling, DNA fragmentation, electrophoresis, blotting, hybridization, washing, and autoradiography

HMGB2 (1,194 words) [view diff] exact match in snippet view article find links to article

interferon-beta production nucleosome assembly DNA recombination apoptotic DNA fragmentation male gonad development regulation of transcription, DNA-templated

Caspase 3 (3,392 words) [view diff] exact match in snippet view article find links to article

apoptosis, where it is responsible for chromatin condensation and DNA fragmentation. Elevated levels of a fragment of Caspase-3, p17, in the bloodstream

Eosinophil cationic protein (2,337 words) [view diff] exact match in snippet view article find links to article

in chromatin condensation, sub-G1 population, PARP cleavage, and DNA fragmentation indicate that ECP induces apoptosis in human bronchial epithelial

Cell death (1,909 words) [view diff] exact match in snippet view article find links to article

shrinkage, nuclear fragmentation, chromatin condensation, and chromosomal DNA fragmentation. It is now thought that – in a developmental context – cells are induced

ACIN1 (645 words) [view diff] exact match in snippet view article find links to article

Schulze-Osthoff K, Schwerk C (2006). "Loss of Acinus inhibits oligonucleosomal DNA fragmentation but not chromatin condensation during apoptosis". J. Biol. Chem. 281

Finger (2,886 words) [view diff] exact match in snippet view article find links to article

PMID 33257543. V. Garcia-Martinez, D. Macias et al: Internucleosomal DNA fragmentation and programmed cell death (apoptosis) in the interdigital tissue of

Sperm washing (723 words) [view diff] exact match in snippet view article find links to article

Jurisicova A, Casper RF (September 2001). "Sperm swim-up techniques and DNA fragmentation". Hum. Reprod. 16 (9): 1950–3. doi:10.1093/humrep/16.9.1950. PMID 11527903

Chromosome abnormality (1,966 words) [view diff] exact match in snippet view article find links to article

Gori M, Orvieto R, Piomboni P (2014). "Chromosomal aneuploidies and DNA fragmentation of human spermatozoa from patients exposed to perfluorinated compounds"

Dinophysis (2,467 words) [view diff] exact match in snippet view article find links to article

A.M. (October 2014). "Does the marine biotoxin okadaic acid cause DNA fragmentation in the blue mussel and the pacific oyster?". Marine Environmental

CTL-mediated cytotoxicity (416 words) [view diff] exact match in snippet view article find links to article

activation, which is similar to granzyme B. This ultimately leads to DNA fragmentation. Kindt, Thomas, Richard Goldsby, Barbara Osborne, and Janis Kuby.

Hydroxylation of estradiol (1,786 words) [view diff] exact match in snippet view article find links to article

via induction of caspase-8, followed by caspase-3 and eventually DNA fragmentation. Induction of apoptosis by 2-meOE2 may be p53 dependent or independent

EPIC-Seq (6,409 words) [view diff] exact match in snippet view article find links to article

Henning (April 2022). "Inferring gene expression from cell-free DNA fragmentation profiles". Nature Biotechnology. 40 (4): 585–597. doi:10.1038/s41587-022-01222-4

FOXL2 (2,264 words) [view diff] exact match in snippet view article find links to article

intercellular bridge nucleoplasm Biological process oocyte growth apoptotic DNA fragmentation regulation of transcription, DNA-templated extraocular skeletal muscle

Endonuclease (2,688 words) [view diff] case mismatch in snippet view article find links to article

Takanori (2006-02-01). "Endonuclease Activation and Chromosomal DNA Fragmentation during Apoptosis in Leukemia Cells". International Journal of Hematology

GZMM (543 words) [view diff] exact match in snippet view article find links to article

inhibitor of caspase-activated DNase (CAD) to unleash CAD leading to DNA fragmentation". J. Immunol. 177 (2): 1171–8. doi:10.4049/jimmunol.177.2.1171. PMID 16818775

APAF1 (1,643 words) [view diff] exact match in snippet view article find links to article

apoptotic signaling pathway forebrain development regulation of apoptotic DNA fragmentation protein homooligomerization activation of cysteine-type endopeptidase

Heat shock factor protein 1 (2,454 words) [view diff] exact match in snippet view article find links to article

regulation of inclusion body assembly positive regulation of apoptotic DNA fragmentation cellular response to L-glutamine response to psychosocial stress response

Ashok Agarwal (5,377 words) [view diff] exact match in snippet view article find links to article

SC; Ko, E; Ramasamy, R; Zini, A (2016). "Clinical utility of sperm DNA fragmentation testing: practice recommendations based on clinical scenarios". Transl

Dicer (3,267 words) [view diff] exact match in snippet view article find links to article

production of siRNA involved in RNA interference gene silencing apoptotic DNA fragmentation negative regulation of tumor necrosis factor production NIK/NF-kappaB

TIA1 (1,282 words) [view diff] exact match in snippet view article find links to article

as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein

Deoxyribonuclease ii, lysosomal (187 words) [view diff] exact match in snippet view article find links to article

catabolic process DNA catabolic process, endonucleolytic apoptotic process apoptotic DNA fragmentation regulation of immune response Sources:Amigo / QuickGO

Flap structure-specific endonuclease 1 (2,642 words) [view diff] exact match in snippet view article find links to article

maintenance via semi-conservative replication base-excision repair apoptotic DNA fragmentation retina development in camera-type eye Sources:Amigo / QuickGO

Phospholipid scramblase 1 (1,146 words) [view diff] no match in snippet view article find links to article

resolution of phospholipid scramblase 1 (PLSCR1), caspase-3 activation and DNA-fragmentation in the human hippocampus after cerebral ischemia". Neurochem. Int

Chromosome (6,547 words) [view diff] exact match in snippet view article find links to article

Orvieto R, Piomboni P (November 2015). "Chromosomal aneuploidies and DNA fragmentation of human spermatozoa from patients exposed to perfluorinated compounds"

Importin subunit alpha-5 (1,132 words) [view diff] exact match in snippet view article find links to article

regulation of DNA recombination intracellular transport of virus apoptotic DNA fragmentation protein import into nucleus protein transport modulation by virus

Hemolysin (2,710 words) [view diff] exact match in snippet view article find links to article

since it allows the exchange of monovalent ions that would cause the DNA fragmentation. Some hemolysins damage the erythrocyte membrane by cleaving the phospholipids

AIFM1 (1,545 words) [view diff] exact match in snippet view article find links to article

positive regulation of neuron apoptotic process regulation of apoptotic DNA fragmentation cellular response to hydrogen peroxide intrinsic apoptotic signaling

Steroidogenic factor 1 (3,478 words) [view diff] exact match in snippet view article find links to article

maintaining elevated ACTH levels. Observed morphological changes and DNA fragmentation was consistent with apoptosis and structural regression resulting

Douglas R. Green (954 words) [view diff] exact match in snippet view article find links to article

in T cell hybridomas is due to apoptosis. Morphologic aspects and DNA fragmentation". Journal of Immunology. 144 (9): 3326–33. PMID 1691753. Shi, Y; Glynn

O-Toluidine (1,710 words) [view diff] exact match in snippet view article find links to article

Corbu, C.; Brambilla, G. (2002). "Correlation between induction of DNA fragmentation in urinary bladder cells from rats and humans and tissue-specific

HMGB1 (3,158 words) [view diff] exact match in snippet view article find links to article

integrin-HMGB1 complex Biological process T-helper 1 cell activation apoptotic DNA fragmentation adaptive immune response regulation of transcription by RNA polymerase

KPNB1 (1,942 words) [view diff] exact match in snippet view article find links to article

complex Biological process intracellular transport of virus apoptotic DNA fragmentation Ran protein signal transduction establishment of protein localization

Capacitation (2,027 words) [view diff] exact match in snippet view article find links to article

is the most suitable method to improve fertilization and to reduce DNA fragmentation positive spermatozoa of infertile men". Anatolian Journal of Obstetrics

Deoxyribonuclease 2 beta (396 words) [view diff] exact match in snippet view article find links to article

extracellular region lysosome intracellular anatomical structure Biological process DNA metabolic process apoptotic DNA fragmentation Sources:Amigo / QuickGO

Granzyme B (2,040 words) [view diff] exact match in snippet view article find links to article

release from the mitochondria. Granzyme B can cleave ICAD leading to DNA fragmentation and the laddering pattern associated with apoptosis. Granzyme B has

Apoptosis regulator BAX (2,092 words) [view diff] exact match in snippet view article find links to article

morphogenesis leukocyte homeostasis positive regulation of apoptotic DNA fragmentation mitochondrial fragmentation involved in apoptotic process positive

NMNAT1 (1,469 words) [view diff] exact match in snippet view article find links to article

negative regulation of neuron apoptotic process negative regulation of apoptotic DNA fragmentation nucleotide biosynthetic process Sources:Amigo / QuickGO

Deoxyribonuclease gamma (1,191 words) [view diff] exact match in snippet view article find links to article

cell development apoptotic process programmed cell death apoptotic DNA fragmentation DNA catabolic process, endonucleolytic neutrophil activation involved

MDA-MB-453 (1,323 words) [view diff] exact match in snippet view article find links to article

doi:10.3892/ol.2011.375. ISSN 1792-1074. PMC 3224077. PMID 22121396. "DNA fragmentation and Apoptosis - Flow Cytometry Core Facility". www.icms.qmul.ac.uk

TPEN (1,106 words) [view diff] exact match in snippet view article find links to article

When these T lymphocytes were pretreated with caspase inhibitors, DNA fragmentation (an indicator of apoptosis) was prevented. This suggests that apoptosis

TPEN (1,106 words) [view diff] exact match in snippet view article find links to article

When these T lymphocytes were pretreated with caspase inhibitors, DNA fragmentation (an indicator of apoptosis) was prevented. This suggests that apoptosis

Pyroptosis (3,956 words) [view diff] exact match in snippet view article find links to article

NO YES YES Pore formation NO YES YES Membrane blebbing YES YES NO DNA fragmentation YES YES YES Nucleus intact NO YES NO Mechanism Caspase-1 activation

Liquid biopsy (2,237 words) [view diff] exact match in snippet view article find links to article

Watts C, Brindle KM, Rosenfeld N (2018). "Detection of cell-free DNA fragmentation and copy number alterations in cerebrospinal fluid from glioma patients"

Paleogenomics (2,780 words) [view diff] exact match in snippet view article find links to article

(HTS) to identify depurination (a process that drives post-mortem DNA fragmentation, younger samples present more adenine than guanine), single strand

KCNB1 (3,755 words) [view diff] exact match in snippet view article find links to article

surge of KCNB1 current induces activation of a pro-apoptotic pathway, DNA fragmentation, and caspase activation. Another proposed mechanism for regulation

PAM16 (718 words) [view diff] exact match in snippet view article find links to article

apoptotic process negative regulation of release of cytochrome c from mitochondria negative regulation of apoptotic DNA fragmentation Sources:Amigo / QuickGO

Superoxide dismutase (5,242 words) [view diff] exact match in snippet view article find links to article

(February 2014). "Absence of superoxide dismutase activity causes nuclear DNA fragmentation during the aging process". Biochemical and Biophysical Research Communications

Citrinin (4,183 words) [view diff] exact match in snippet view article find links to article

apoptosis and not necrosis as CTN exposure led to an increase of nuclear DNA fragmentation or breakdown of chromatin, which are both characteristics of apoptosis

Ciprofloxacin (6,684 words) [view diff] exact match in snippet view article find links to article

separate bacterial DNA, thereby inhibiting cell division. Bacterial DNA fragmentation will occur as a result of inhibition of the enzymes. Ciprofloxacin

Ceramide kinase (1,895 words) [view diff] exact match in snippet view article find links to article

apoptosis by inhibiting the caspase-9/caspase-3 pathway and preventing DNA fragmentation in macrophages. This is thought to occur via C-1-P interacting with

Adenosine A2A receptor (5,133 words) [view diff] exact match in snippet view article find links to article

PMC 3427751. PMID 7775460. Szondy Z (December 1994). "Adenosine stimulates DNA fragmentation in human thymocytes by Ca(2+)-mediated mechanisms". The Biochemical

H2AFX (2,783 words) [view diff] exact match in snippet view article find links to article

Nieves-Neira W, Boon C, Pommier Y, Bonner WM (Mar 2000). "Initiation of DNA fragmentation during apoptosis induces phosphorylation of H2AX histone at serine

P16 (4,271 words) [view diff] exact match in snippet view article find links to article

endopeptidase activity involved in apoptotic process regulation of apoptotic DNA fragmentation positive regulation of transcription by RNA polymerase II positive

T helper cell (6,597 words) [view diff] exact match in snippet view article find links to article

apoptose virus-infected cells and to induce host as well as viral DNA fragmentation. IFN alpha/beta can suppress transcription to avoid virus replication

Self-incompatibility (4,787 words) [view diff] exact match in snippet view article find links to article

Jordan ND, Franklin FC, Franklin-Tong VE (August 2000). "Evidence for DNA fragmentation triggered in the self-incompatibility response in pollen of Papaver

Infertility (8,729 words) [view diff] exact match in snippet view article find links to article

this assay, the sperm's DNA will be denaturated and renatured. If DNA fragmentation occurs (double and single-strand-breaks) a halo will not appear surrounding

List of MeSH codes (G04) (2,119 words) [view diff] case mismatch in snippet view article

apoptosis MeSH G04.335.139.160.060 – anoikis MeSH G04.335.139.160.200 – dna fragmentation MeSH G04.335.139.399 – autophagy MeSH G04.335.139.638 – necrosis MeSH G04

CDKN2A (3,317 words) [view diff] exact match in snippet view article find links to article

endopeptidase activity involved in apoptotic process regulation of apoptotic DNA fragmentation positive regulation of transcription by RNA polymerase II positive

Benzodiazepine (16,665 words) [view diff] exact match in snippet view article find links to article

Finollo R, Ledda A, Brambilla G (January 1989). "Absence of liver DNA fragmentation in rats treated with high oral doses of 32 benzodiazepine drugs".

MDMA (15,978 words) [view diff] exact match in snippet view article find links to article

Giorgi FS, Blandini F, Nigro M, Ruggieri S, et al. (September 2007). "DNA fragmentation and oxidative stress in the hippocampal formation: a bridge between

Entosis (1,352 words) [view diff] exact match in snippet view article find links to article

escape from host cell. In clinical cancer specimens, evidence of DNA fragmentation has been found suggesting that non-apoptotic cell death may be a common

Ranjith Ramasamy (1,400 words) [view diff] exact match in snippet view article find links to article

mentorship, clinical scholarship and research. "Clinical utility of sperm DNA fragmentation testing: practice recommendations based on clinical scenarios", A

Anoxic depolarization in the brain (2,385 words) [view diff] exact match in snippet view article find links to article

lipolysis, proteolysis, cell swelling, microtubule disaggregation, and DNA fragmentation. Neurons are more susceptible to brain ischemia than the supporting

Actin (18,282 words) [view diff] exact match in snippet view article find links to article

inhibitors, but not caspase inhibitors, prevent actin proteolysis and DNA fragmentation during apoptosis". Journal of Cell Science. 111 (Pt 6): 713–722. doi:10

Mega-telomere (2,185 words) [view diff] exact match in snippet view article find links to article

individual variability. Slot blot, however, is conducted without DNA fragmentation or separation, rather whole genomic DNA is used to quantify the total

Whole genome bisulfite sequencing (2,517 words) [view diff] exact match in snippet view article find links to article

assay coverage and efficacy. Library preparation protocols undergo DNA fragmentation, end repair, dA-tailing, and adapter ligation prior to bisulfite treatment

HPG80 (5,038 words) [view diff] exact match in snippet view article find links to article

significant loss of caspase 9 and caspase 3 activation and a decrease in DNA fragmentation. Therefore, the effect of hPG80 on cell survival results from both

Inflammasome (7,823 words) [view diff] exact match in snippet view article find links to article

secretion and natural killer cell activation, inactivation of IL-33, DNA fragmentation and cell pore formation, inhibition of glycolytic enzymes, activation

Cell cycle hypothesis of Alzheimer's disease (1,732 words) [view diff] exact match in snippet view article find links to article

has still been proven although the presence of apoptotic bodies, DNA fragmentation, granulated and marginated chromatin and shrunken and irregular cell

Valina L. Dawson (3,374 words) [view diff] exact match in snippet view article find links to article

the nucleus where the nuclease activity of MIF leads to large scale DNA fragmentation. To distinguish this form of cell death from other cell death signaling

Obesity and fertility (5,899 words) [view diff] exact match in snippet view article find links to article

associated with a reduction in sperm motility, an increase in sperm DNA fragmentation, and increased sperm oxidative stress. Sleep apnea is defined as a

John Aitken (biologist) (3,437 words) [view diff] exact match in snippet view article

and functional integrity of human spermatozoa: lipid peroxidation, DNA fragmentation and effectiveness of antioxidants". Human Reproduction. 13 (6): 1429–36

Circulating free DNA (4,208 words) [view diff] exact match in snippet view article find links to article

Mahya; et al. (April 2022). "Inferring gene expression from cell-free DNA fragmentation profiles". Nature Biotechnology. 40 (4): 585–597. doi:10.1038/s41587-022-01222-4

Health effects of electronic cigarettes (35,211 words) [view diff] exact match in snippet view article find links to article

of OxPhos electron transport chain (ETC) complex IV subunit) and DNA fragmentation in lung fibroblasts." A 2013 review found metallic and nanoparticles

Sonodynamic therapy (9,348 words) [view diff] exact match in snippet view article find links to article

concentration of calcium plays a significant role in cell death through DNA fragmentation and mitochondrial membrane disruption. While a decreased concentration