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searching for Imatinib 21 found (666 total)

alternate case: imatinib

K562 cells (1,386 words) [view diff] exact match in snippet view article find links to article

cycle regulation provides targets for cancer drugs. One of these drugs is Imatinib, which inhibits BCR/ABL causing growth to cease and apoptosis to begin

ABL2 (1,464 words) [view diff] exact match in snippet view article find links to article

domain in complex with INNO-406 2f4j: Structure of the Kinase Domain of an Imatinib-Resistant Abl Mutant in Complex with the Aurora Kinase Inhibitor VX-680

Chordoma (2,201 words) [view diff] exact match in snippet view article find links to article

objective response rate with median progression free survival of 18 months Imatinib: 2% objective response rate with median progression free survival of 9

Acute myeloblastic leukemia with maturation (3,160 words) [view diff] exact match in snippet view article find links to article

fusion oncoprotein – BCR-Abl. The developed tyrosine kinase inhibitor, imatinib mesylate, has had a tremendous effect on stopping cancer progression in

Mir-451 microRNA (828 words) [view diff] exact match in snippet view article find links to article

Lithwick-Yanai G, Amariglio N, Rechavi G, Givol D (2008). "MIR-451 and Imatinib mesylate inhibit tumor growth of Glioblastoma stem cells". Biochem Biophys

Mir-451 microRNA (828 words) [view diff] exact match in snippet view article find links to article

Lithwick-Yanai G, Amariglio N, Rechavi G, Givol D (2008). "MIR-451 and Imatinib mesylate inhibit tumor growth of Glioblastoma stem cells". Biochem Biophys

Erdheim–Chester disease (2,228 words) [view diff] exact match in snippet view article find links to article

Charlotte F, Salvatierra J, Wechsler B, Graux C, et al. (June 2008). "Imatinib mesylate for platelet-derived growth factor receptor-beta-positive Erdheim-Chester

GlaxoSmithKline Prize (135 words) [view diff] exact match in snippet view article find links to article

development and disease." - 2014 Nicholas Lydon "for the development of the drug imatinib, a targeted tyrosine kinase inhibitor that has transformed the treatment

Omacetaxine mepesuccinate (777 words) [view diff] exact match in snippet view article find links to article

patients showed a cytogenetic response. A study in patients who had failed imatinib and who had the drug resistant T315I mutation achieved cytogenetic response

Anagrelide (877 words) [view diff] exact match in snippet view article find links to article

2024. Voglová J, Maisnar V, Beránek M, Chrobák L (2006). "[Combination of imatinib and anagrelide in treatment of chronic myeloid leukemia in blastic phase]"

Wolfram Samlowski (1,658 words) [view diff] exact match in snippet view article find links to article

and neck (SCCHN): Phase II (S0007). Co-investigator. A Phase II trial of imatinib mesylate (Gleevec) in neuroendocrine carcinoma of the skin (Merkel Cell

Portopulmonary hypertension (3,181 words) [view diff] exact match in snippet view article find links to article

morphological changes persist, sometimes necessitating lung transplantation. Imatinib, designed to treat chronic myeloid leukemia, has been shown to reverse

Tyrosine-protein kinase Yes (1,028 words) [view diff] exact match in snippet view article find links to article

kinase domain in complex with covalent inhibitor PD168393 2oiq: Crystal Structure of chicken c-Src kinase domain in complex with the cancer drug imatinib.

John Kuriyan (628 words) [view diff] exact match in snippet view article find links to article

mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia The

Ariel Fernandez (758 words) [view diff] exact match in snippet view article find links to article

1038/nrd2524. S2CID 27083179. Demetri G. D. Structural reengineering of imatinib to decrease cardiac risk in cancer therapy.2007 Dec 3; J Clin Invest. 117(12):3650–3653

Ninein (911 words) [view diff] exact match in snippet view article find links to article

protein, is fused to PDGFRB in a patient with a t(5;14)(q33;q24) and an imatinib-responsive myeloproliferative disorder". Cancer Res. 64 (8): 2673–6. doi:10

Somatic evolution in cancer (9,913 words) [view diff] exact match in snippet view article find links to article

copies of TYMS, thereby diluting the drug's effect. In the case of Gleevec (Imatinib), which targets the BCR-ABL fusion gene in chronic myeloid leukemia, resistance

Lankenau Institute for Medical Research (507 words) [view diff] exact match in snippet view article find links to article

first molecule-targeted drug to be created for cancer therapy, Gleevec (imatinib), acts by blocking this genetic abnormality.[citation needed] LHRI researcher

Salivary gland tumour (1,998 words) [view diff] exact match in snippet view article find links to article

histogenetic origin of the tumor cells. Various targeted agents, such as imatinib, cetuximab, gefitinib, trastuzumab, had been used for exploring new treatment

Public Eye on Davos (1,818 words) [view diff] exact match in snippet view article find links to article

Novartis received the Swiss Award for the patenting of the cancer drug Imatinib, forcing a halt in production of Indian generics. As a result, ten thousand

Signet ring cell carcinoma (2,270 words) [view diff] exact match in snippet view article find links to article

hypertension and coagulation problems that could be successfully treated with Imatinib. These aggressive tumors are generally diagnosed at advanced stages and