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searching for Caspase 2 20 found (37 total)

alternate case: caspase 2

Sally Kornbluth (1,125 words) [view diff] no match in snippet view article find links to article

length of female fertility in vertebrates, in a mechanism regulated by caspase-2. At Duke she received a Research Mentoring award in 2012 and the Distinguished

Anterior ischemic optic neuropathy (2,629 words) [view diff] exact match in snippet view article find links to article

gov/). This trial will test the use of a synthetic siRNA that blocks caspase 2, an important enzyme in the apoptosis cycle. In addition to such research

Xenopus (5,807 words) [view diff] no match in snippet view article find links to article

Recently, oocytes were used recently to study the biochemical mechanisms of caspase-2 activation; importantly, this mechanism turns out to be conserved in mammals

A. Thomas Look (1,392 words) [view diff] no match in snippet view article find links to article

define distinct oncogenic subgroups in T-ALL Discovery of CHK1 suppressed caspase-2 apoptotic pathway in response to DNA damage Discovery of activating ALK

ContraPest (941 words) [view diff] no match in snippet view article find links to article

Kolesnick, Richard N.; Yuan, Junying; Flavell, Richard A. (2003-01-01). "Bax, caspase-2, and caspase-3 are required for ovarian follicle loss caused by 4-vinylcyclohexene

Vinylcyclohexene dioxide (527 words) [view diff] no match in snippet view article find links to article

Kolesnick, Richard N.; Yuan, Junying; Flavell, Richard A. (2003-01-01). "Bax, caspase-2, and caspase-3 are required for ovarian follicle loss caused by 4-vinylcyclohexene

MZB1 (559 words) [view diff] no match in snippet view article find links to article

F, Cooper NR (August 2001). "Characterization of a novel proapoptotic caspase-2- and caspase-9-binding protein". The Journal of Biological Chemistry.

Hexokinase II (2,542 words) [view diff] no match in snippet view article find links to article

the mitochondria potentiates cisplatin induced cytotoxicity through a caspase-2 dependent mechanism". Cell Cycle. 8 (20): 3355–64. doi:10.4161/cc.8.20

AIFM1 (1,545 words) [view diff] no match in snippet view article find links to article

Prévost MC, Alzari PM, Kroemer G (January 1999). "Mitochondrial release of caspase-2 and -9 during the apoptotic process". The Journal of Experimental Medicine

GOLGA3 (905 words) [view diff] no match in snippet view article find links to article

PMC 16267. PMID 10737800. Mancini M, Machamer CE, Roy S, et al. (2000). "Caspase-2 Is Localized at the Golgi Complex and Cleaves Golgin-160 during Apoptosis"

Bcl-2 (4,564 words) [view diff] no match in snippet view article find links to article

Srinivasula SM, Druilhe A, Fernandes-Alnemri T, Alnemri ES (April 2002). "Caspase-2 induces apoptosis by releasing proapoptotic proteins from mitochondria"

Tetrapeptide (1,938 words) [view diff] no match in snippet view article find links to article

accompanied by the processing of activation of caspase-3 and potentially caspase-2. Benzyloxycarbonyl-Val-Ala-Asp-(OMe)-fluoromethylketone (zVAD.fmk), a

YWHAZ (3,619 words) [view diff] no match in snippet view article find links to article

with many apoptotic proteins, including Raf kinases, BAX, BAD, NOXA, and caspase-2. For the most part, 14-3-3ζ negatively regulates apoptosis by binding

List of EC numbers (EC 3) (15,555 words) [view diff] no match in snippet view article

calpain-1 EC 3.4.22.53: calpain-2 EC 3.4.22.54: calpain-3 EC 3.4.22.55: caspase-2 EC 3.4.22.56: caspase-3 EC 3.4.22.57: caspase-4 EC 3.4.22.58: caspase-5

James J. Chou (1,422 words) [view diff] no match in snippet view article find links to article

Structure of the RAIDD CARD Domain and Model for CARD/CARD Interaction in Caspase-2 and Caspase-9 Recruitment". Cell. 94 (2): 171–80. doi:10.1016/s0092-8674(00)81417-8

RNA silencing (5,449 words) [view diff] exact match in snippet view article find links to article

disorders QPI-1007 Non-arteritic anterior ischaemic optic neuropathy Caspase 2 Ocular and retinal disorders AGN211745 Age-related macular degeneration

Karen Ashe (3,047 words) [view diff] no match in snippet view article find links to article

Hlynialuk C, Zahs K, Ramsden M, Cleary J, Ashe KH (November 2016). "Caspase-2 cleavage of tau reversibly impairs memory". Nat Med. 22 (11): 1268–1276

Protein acetylation (4,895 words) [view diff] no match in snippet view article find links to article

because of reduced protein N-terminal acetylation. But in contrast, the caspase-2, which is acetylated by NatA, can interact with the adaptor protein RIP

RIPK1 (4,951 words) [view diff] no match in snippet view article find links to article

(February 1997). "CRADD, a novel human apoptotic adaptor molecule for caspase-2, and FasL/tumor necrosis factor receptor-interacting protein RIP". Cancer

RBM10 (5,530 words) [view diff] exact match in snippet view article find links to article

Sutherland LC, Wu JY (October 2008). "Up-regulation of the proapoptotic caspase 2 splicing isoform by a candidate tumor suppressor, RBM5". Proceedings of