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searching for Necroptosis 30 found (232 total)

alternate case: necroptosis

Death domain (1,019 words) [view diff] exact match in snippet view article find links to article

these alterations occur in genes encoding mediators of apoptosis or necroptosis, potentially enabling the development of resistance to cell death, an
RIPK3 (774 words) [view diff] exact match in snippet view article find links to article
tumor necrosis factor (TNF) receptor-I signaling complex, and can induce necroptosis by interaction with RIPK1 and MLKL in a protein complex termed the necrosome
ADP-ribosylation (3,346 words) [view diff] exact match in snippet view article find links to article
failure of caspase activation under stress conditions were to occur, necroptosis would take place. Overactivation of PARPs has led to a necrotic cell
ZBP1 (897 words) [view diff] exact match in snippet view article find links to article
cumulating in a form of caspase independent, inflammatory cell death called necroptosis. A follow up study identified that ZBP1 senses the IAV ribonucleoprotein
CD14 (779 words) [view diff] exact match in snippet view article find links to article
pathway apoptotic process innate immune response GO:0060554, GO:0060555 necroptosis negative regulation of MyD88-independent toll-like receptor signaling
TRPM7 (420 words) [view diff] exact match in snippet view article find links to article
transmembrane transport protein autophosphorylation GO:0060554, GO:0060555 necroptosis calcium ion transport transmembrane transport Sources:Amigo / QuickGO
TLR3 (1,058 words) [view diff] exact match in snippet view article find links to article
regulation of transcription by RNA polymerase II GO:0060554, GO:0060555 necroptosis apoptotic signaling pathway negative regulation of MyD88-independent
Cry6Aa (1,445 words) [view diff] exact match in snippet view article find links to article
Long, J., and Ryan, K. (2012) "New frontiers in promoting tumour cell death: targeting apoptosis, necroptosis and autophagy". Oncogene. 31, 5045-5060
CYLD (gene) (1,063 words) [view diff] exact match in snippet view article
regulation of T cell receptor signaling pathway GO:0060554, GO:0060555 necroptosis protein K48-linked deubiquitination ripoptosome assembly involved in
Chimaphila umbellata (449 words) [view diff] exact match in snippet view article find links to article
anti-proliferative effect on human breast cancer cells via RIP1K/RIP3K-mediated necroptosis. Phytomedicine Plus, p.100159. Blanchan, Neltje (2005). Wild Flowers
Chrysophanol (1,423 words) [view diff] exact match in snippet view article find links to article
PMID 25206913. Choi JS (June 2016). "Chrysophanic Acid Induces Necrosis but not Necroptosis in Human Renal Cell Carcinoma Caki-2 Cells". Journal of Cancer Prevention
Chimaphila umbellata (449 words) [view diff] exact match in snippet view article find links to article
anti-proliferative effect on human breast cancer cells via RIP1K/RIP3K-mediated necroptosis. Phytomedicine Plus, p.100159. Blanchan, Neltje (2005). Wild Flowers
Fas ligand (2,083 words) [view diff] exact match in snippet view article find links to article
endopeptidase activity involved in apoptotic process GO:0060554, GO:0060555 necroptosis apoptotic signaling pathway negative regulation of extrinsic apoptotic
PGAM5 (107 words) [view diff] exact match in snippet view article find links to article
Biological process protein dephosphorylation GO:0060554, GO:0060555 necroptosis programmed cell death dephosphorylation GO:0032320, GO:0032321, GO:0032855
TICAM2 (480 words) [view diff] exact match in snippet view article find links to article
receptor signaling pathway signal transduction GO:0060554, GO:0060555 necroptosis apoptotic signaling pathway negative regulation of MyD88-independent
Lymphocyte antigen 96 (1,498 words) [view diff] exact match in snippet view article find links to article
receptor signaling pathway innate immune response GO:0060554, GO:0060555 necroptosis apoptotic signaling pathway toll-like receptor signaling pathway Sources:Amigo
ITPK1 (618 words) [view diff] exact match in snippet view article find links to article
process neural tube development signal transduction dephosphorylation GO:0060554, GO:0060555 necroptosis inositol phosphorylation Sources:Amigo / QuickGO
Emricasan (473 words) [view diff] exact match in snippet view article find links to article
inhibitor emricasan combines with the SMAC mimetic birinapant to induce necroptosis and treat acute myeloid leukemia". Science Translational Medicine. 8
Thirumala-Devi Kanneganti (3,500 words) [view diff] exact match in snippet view article find links to article
inflammasome/pyroptosis and also showed ZBP1 is a key regulator of apoptosis and necroptosis, establishing it as an upstream cell death sensor. This study also highlighted
Baculoviral IAP repeat-containing protein 2 (1,876 words) [view diff] exact match in snippet view article find links to article
ubiquitin-dependent protein catabolic process GO:0060554, GO:0060555 necroptosis apoptotic process protein deubiquitination cellular response to tumor
Crystallopathy (821 words) [view diff] exact match in snippet view article find links to article
IL-1b antagonists, NLRP3-antagonists, or blockers of ferroptosis and necroptosis. For protein-based crystallopathy, pharmacologic chaperones, protein
Prion (9,421 words) [view diff] exact match in snippet view article find links to article
doi:10.1038/news.2010.29. S2CID 84980140. Nailwal H, Chan FK (2019). "Necroptosis in anti-viral inflammation". Nature. 26 (1): 4–13. doi:10.1038/s41418-018-0172-x
TLR4 (5,509 words) [view diff] exact match in snippet view article find links to article
bacterium toll-like receptor signaling pathway GO:0060554, GO:0060555 necroptosis apoptotic signaling pathway negative regulation of MyD88-independent
Pseudoenzyme (1,379 words) [view diff] exact match in snippet view article find links to article
Silke J, Alexander WS (September 2013). "The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism". Immunity. 39 (3): 443–53. doi:10.1016/j
PPIF (1,579 words) [view diff] exact match in snippet view article find links to article
of release of cytochrome c from mitochondria GO:0060554, GO:0060555 necroptosis negative regulation of oxidative phosphorylation cellular response to
Bing Liu (scientist) (778 words) [view diff] exact match in snippet view article
Total Body Irradiation Mitigation by Drugs that Block Apoptosis and Necroptosis," Radiation Research, [Epub ahead of print] (2020). doi: 10.1667/RR15486
Bradlee Heckmann (1,064 words) [view diff] exact match in snippet view article find links to article
Green, Douglas R. (January 2019). "Crashing the computer: apoptosis vs. necroptosis in neuroinflammation". Cell Death & Differentiation. 26 (1): 41–52. doi:10
Damage-associated molecular pattern (3,562 words) [view diff] exact match in snippet view article find links to article
PMID 24762401. Kaczmarek A, Vandenabeele P, Krysko DV (February 2013). "Necroptosis: the release of damage-associated molecular patterns and its physiological
DNM1L (2,564 words) [view diff] exact match in snippet view article find links to article
of release of cytochrome c from mitochondria GO:0060554, GO:0060555 necroptosis dynamin family protein polymerization involved in mitochondrial fission
P53 (13,722 words) [view diff] exact match in snippet view article find links to article
stress regulation of thymocyte apoptotic process GO:0060554, GO:0060555 necroptosis cellular response to UV-C positive regulation of cell aging negative