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searching for Immunogenicity 418 found (568 total)

alternate case: immunogenicity

Nanocovax (3,455 words) [view diff] exact match in snippet view article find links to article

having been successfully produced on a laboratory scale and provoked immunogenicity during animal testing. Preclinical studies of Nanocovax were conducted

produced thanks to their qualities of immunogenicity, immunogenic stability, and safety. Specific immunogenicity properties include highly efficient gene

was found to be safe and well tolerated. "Safety, Reactogenicity, and Immunogenicity of a Recombinant SARS-CoV-2 Vaccine LYB001 in healthy adults: a randomized

"An optimized purified inactivated Zika vaccine provides sustained immunogenicity and protection in cynomolgus macaques". npj Vaccines. 5 (1): 19. doi:10

Phase I trial were launched to assess safety, reactogenicity, and immunogenicity at multiple dose levels with 151 participants in Perth, Australia using

and using a conventional needle gives poor results and leads to low immunogenicity. In February 2020, Cadila Healthcare decided to develop a DNA plasmid

vaccine was non-inferior to a booster dose of BNT162b2. "Safety and Immunogenicity of an Intranasal RSV Vaccine Expressing SARS-CoV-2 Spike Protein (COVID-19

far on scytovirin and griffithsin have not shown a similar level of immunogenicity. Scytovirin and griffithsin are currently being investigated as potential

like to lead to allergic or auto-immune responses. Disadvantages: Poor immunogenicity. Unstable in cells. Lack of native conformation. Only effective for

immunogenic alone, adjuvantation is essential for a RBD-based vaccine immunogenicity. Researchers at the Precision Vaccine Program at Boston Children's Hospital

Clinical trial number NCT04756323 for "A Study to Evaluate Safety and Immunogenicity of Inactivated SARS-CoV-2 Vaccine (Vero Cells) in Healthy Population

Retrieved 29 April 2022. "A Study to Evaluate Safety, Reactogenicity, and Immunogenicity of mRNA-1283 and mRNA-1273 Vaccines in Healthy Adults Between 18 Years

ORF3a (previously known as X1 or U274) is a gene found in coronaviruses of the subgenus Sarbecovirus, including SARS-CoV and SARS-CoV-2. It encodes an

3389/fimmu.2022.836745. PMC 9179012. PMID 35693788. "Phase I, Safety and Immunogenicity of Razi SARS-CoV-2 recombinant Spike protein vaccine (Razi Cov Pars)

NCT04671017 for "Dose Finding Study to Evaluate Safety, Tolerability and Immunogenicity of an Inactiviated Adjuvanted Sars-Cov-2 Virus Vaccine Candidate Against

Bloomberg Markets. Clinical trial number NCT04666012 for "Safety and Immunogenicity Study of AdCLD-CoV19: A COVID-19 Preventive Vaccine in Healthy Volunteers"

"Efficacy, Immunogenicity and Safety of Inactivated Erucov-Vac Compared With Placebo in COVID-19 " at ClinicalTrials.gov "Efficacy, Immunogenicity, and Safety

commercial production. Early results from H5N1 clinical trials showed poor immunogenicity compared to the 15-mcg dose that induces immunity in a seasonal flu

Codagenix's nasal COVID-19 vaccine". mint. 22 September 2020. "Safety and Immunogenicity of COVI-VAC, a Live Attenuated Vaccine Against COVID-19". ClinicalTrials

Medicine. Retrieved 11 March 2021. "A Study to Evaluate the Safety and Immunogenicity of MVC-COV1901 Against COVID-19". clinicaltrials.gov. United States

2020. Clinical trial number NCT04336410 for "Safety, Tolerability and Immunogenicity of INO-4800 for COVID-19 in Healthy Volunteers" at ClinicalTrials.gov

of its third domestic COVID vaccine". Al Jazeera. "Phase 1, safety, immunogenicity and dose finding for two strengths of 0.5 × 10^6 and 2.5 × 10^6 (TCID50)

began Phase IIb trials on 481 participants to evaluate the safety and immunogenicity of Ad5-nCoV for children ages 6–17 and elderly individuals ages 56 and

volunteers to evaluate the safety, tolerability, and initial assessment of immunogenicity of the vaccine. The clinical trial Phase 2 enrolled 300 volunteers at

Reactogenicity and Immunogenicity Study of ReCOV" at ClinicalTrials.gov Clinical trial number NCT05084989 for "Efficacy, Safety, and Immunogenicity Study of the

study on February 23, 2021. The study is titled "Safety, Tolerance and Immunogenicity of EuCorVac-19 for the Prevention of COVID-19 in Healthy Adults" As

therapeutics" (PDF). Clinical trial number NCT04563702 for "Safety and Immunogenicity Trial of an Oral SARS-CoV-2 Vaccine (VXA-CoV2-1) for Prevention of COVID-19

Retrieved 7 July 2021. Clinical trial number NCT04352608 for "Safety and Immunogenicity Study of Inactivated Vaccine for Prophylaxis of SARS CoV-2 Infection

from the original on 3 May 2021. Retrieved 11 March 2021. "Safety and Immunogenicity of an Intranasal RSV Vaccine Expressing SARS-CoV-2 Spike Protein (COVID-19

Times. Retrieved 2 March 2021. Clinical trial number NCT04691908 for "Immunogenicity, Efficacy and Safety of QazCovid-in® COVID-19 Vaccine" at ClinicalTrials

DNA-based vaccine that encodes the SARS-CoV-2 spike protein. "Safety and Immunogenicity Study of GX-19, a COVID-19 Preventive DNA Vaccine in Healthy Adults"

Wilson RM, Douglas CA, Tattersall RB, Reeves WG (September 1985). "Immunogenicity of highly purified bovine insulin: a comparison with conventional bovine

attractive vaccine target for coronaviruses but is constrained by limited immunogenicity, however a dimeric form of MERS-CoV RBD offers greater protection. The

therapeutics" (PDF). Clinical trial number NCT04412538 for "Safety and Immunogenicity Study of an Inactivated SARS-CoV-2 Vaccine for Preventing Against COVID-19"

"SOBERANA 02-FaseIII". Retrieved 2021-09-08. "IRCT | Efficacy, safety, and immunogenicity of Soberana recombinant vaccine (product of Finlay Institute) based

Sarangi V, et al. (11 November 2021). "Efficacy, safety, and lot-to-lot immunogenicity of an inactivated SARS-CoV-2 vaccine (BBV152): interim results of a

588 participants. Researchers reported day 42 interim safety 17 and immunogenicity data from a Phase II, randomized, placebo-controlled trial in Adults

structural differences of penems from other β-lactams may be reduced immunogenicity and immunogenic cross-reactivity. Richard Wise (1990). "The carbapenems

Placebo-Controlled, Dose-Escalation Study to Evaluate the Safety, Immunogenicity and Potential Efficacy of an rVSV-SARS-CoV-2-S Vaccine (IIBR-100) in

(cBSA) is highly positively charged protein with significantly increased immunogenicity. This change possesses a greater number of possible conjugated antigens

Becker S, Belij-Rammerstorfer S, et al. (August 2020). "Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report

variable immunogenicity, with the antigen that stimulates the strongest response being the immunodominant one. The different levels of immunogenicity amongst

NCT04545749 for "A Study to Evaluate the Safety, Tolerability, and Immunogenicity of UB-612 COVID-19 Vaccine" at ClinicalTrials.gov Clinical trial number

"A Randomised, Controlled, Phase 1 Study to Evaluate the Safety and Immunogenicity of a Candidate Adjuvanted Recombinant Protein SARS-COV-2 Vaccine in

M; Koopmeiners J; de Vos A; Horwith G; Pentel PR (2005). "Safety and immunogenicity of a nicotine conjugate vaccine in current smokers". Clinical Pharmacology

July 2020. "A Phase 2/3 study to determine the efficacy, safety and immunogenicity of the candidate Coronavirus Disease (COVID-19) vaccine ChAdOx1 nCoV-19"

spermatids. Because of their tumor-restricted expression and strong in vivo immunogenicity, CT antigens are identified as ideal targets for tumor specific immunotherapeutic

Transdifferentiation, also known as lineage reprogramming, is the process in which one mature somatic cell is transformed into another mature somatic cell

Inequalities in Global Health. Retrieved September 20, 2023. "Safety and Immunogenicity of a Human Hookworm Candidate Vaccine With or Without Additional Adjuvant

participants, testing three dose levels for safety, tolerability, and immunogenicity. The trial was expected to be complete by 15 February 2021, with full

ISBN 0-07-138076-0. "Phase 2 Study to Evaluate Safety, Pharmacokinetics, Immunogenicity and Pharmacodynamics/Efficacy of EDI200 in Male Infants With X-Linked

rabbits (Leenaars et al. 1994). Specol can be used for antigens of low immunogenicity and can be administered equally effectively by the subcutaneous or intraperitoneal

experiments with mice is ~75%. The lack of efficacy is due to variability of immunogenicity from one animal to another. Even when exposed to the exact same vaccine

027. PMID 22633322. Fujiwara RT, Bethony J, Bueno LL, et al. (2005). "Immunogenicity of the hookworm Na-ASP-2 vaccine candidate: characterization of humoral

pseudouridine-incorporated mRNA by providing enhanced protein expression and reduced immunogenicity in mammalian cell lines and mice". Journal of Controlled Release. 217:

Medicine. 6 August 2021. Retrieved 6 August 2021. "A Phase 1/2 Safety and Immunogenicity Trial of COVID-19 Vaccine COVIVAC". clinicaltrials.gov. United States

Zinc-finger nucleases (ZFNs) are artificial restriction enzymes generated by fusing a zinc finger DNA-binding domain to a DNA-cleavage domain. Zinc finger

Clinical trial number NCT04741061 for "Study to Evaluate Efficacy, Immunogenicity and Safety of the Sputnik-Light (SPUTNIK-LIGHT)" at ClinicalTrials.gov

India's health ministry said its drug regulator had found that safety and immunogenicity data from a local trial of Sputnik V coronavirus vaccine was comparable

and Immunogenicity of BVRS-GamVac". Archived from the original on 18 March 2020. Retrieved 18 March 2020. "Safety, Tolerability and Immunogenicity of Vaccine

Population. This Study is Designed to Evaluate Safety, Tolerability, and Immunogenicity of PTX-COVID19-B Vaccine in Healthy Seronegative Adults Aged 18-64"

from the original on 28 July 2021. Retrieved 28 July 2021. "Safety and Immunogenicity Study of SARS-CoV-2 Nanoparticle Vaccine (GBP510) Adjuvanted With or

on 21 September 2021. Retrieved 22 Sep 2021. "Assess the Safety and Immunogenicity of NDV-HXP-S Vaccine in Thailand". ClinicalTrials.gov. 21 February 2021

Molecule in Nonhuman Primates: Evaluation of Activity and Impact of Immunogenicity". Clin. Cancer Res. 24 (11): 2631–2641. doi:10.1158/1078-0432.CCR-17-2265

As of 2009, the manufacturer was conducting a trial to compare the immunogenicity and safety of Cervarix with Gardasil. Subsequent studies showed Cervarix

Harmonization ICH and WHO Guidance. O-acetylated polysaccharides influence the immunogenicity of meningococcal vaccines. It is well known that O acetylated at carbon

September 29, 2011. Mothe B, et al. (February 26, 2015). "Safety and immunogenicity of a modified vaccinia Ankara-based HIV-1 vaccine (MVA-B) in HIV-1-infected

inactivated vaccines is quick, the immunogenicity is poor. Live attenuated vaccines possess adequate immunogenicity but poor security and a lengthy development

Harmonization ICH and WHO Guidance. O-acetylated polysaccharides influence the immunogenicity of meningococcal vaccines. It is well known that O acetylated at carbon

inactivated vaccines is quick, the immunogenicity is poor. Live attenuated vaccines possess adequate immunogenicity but poor security and a lengthy development

Buckwold SL (October 1996). "Flanking residues alter antigenicity and immunogenicity of multi-unit CTL epitopes". Journal of Immunology. 157 (8): 3242–9

G, Luo B, Wang W, Liu P, Guo W, Yang X (January 2021). "Safety and immunogenicity of an inactivated SARS-CoV-2 vaccine, BBIBP-CorV: a randomised, double-blind

chain. 2axf: The Immunogenicity of a Viral Cytotoxic T Cell Epitope is controlled by its MHC-bound Conformation 2axg: The Immunogenicity of a Viral Cytotoxic

vaccination.[citation needed] GeoVax published results of Phase 1 safety and immunogenicity testing for its preventive vaccine trial on March 1, 2011. Based on

promoter had much higher expression rates. More recently, expression and immunogenicity have been further increased in model systems by the use of the cytomegalovirus

chemically linked to the Neisseria meningitidis outer protein P64k for immunogenicity; Montanide ISA 51 is used as an adjuvant to potentiate the immune response

placebo-controlled phase I clinical trial to evaluate the safety and immunogenicity of mRNACOVID-19 vaccine in healthy susceptible populations aged 18 years

NCT05043285. Retrieved 14 September 2021. "Safety, Tolerability and Immunogenicity of SCTV01C in Healthy Population Aged ≥18 Years Previously Unvaccinated"

sequential and adaptive study to assess safety, reactogenicity and explore immunogenicity of the vaccine. Phase IIa involved 100 Cubans, and phase IIb of the

found to enhance the immunogenicity of bacterial polysaccharides. The pharmaceutical company Wyeth took advantage of this immunogenicity in the 1990s when

immunology Thaunat, Olivier; Morelon, Emmanuel (2007). "Modulation of Immunogenicity". In Lanzetta, Marco; Dubernard, Jean-Michel (eds.). Hand transplantation

Lee JM, Kim HG, Chung DK, Park JW (October 2004). "Comparison of the immunogenicity of recombinant VP2 and VP3 of infectious pancreatic necrosis virus and

Spike (S) glycoprotein (sometimes also called spike protein, formerly known as E2) is the largest of the four major structural proteins found in coronaviruses

seroprevalence: improved systems for vector derivation and comparative immunogenicity". PLOS ONE. 7 (7): e40385. Bibcode:2012PLoSO...740385D. doi:10.1371/journal

was developed by NIAID, that were tested separately for safety and immunogenicity. The vaccine passed phase I trials and phase II studies in the US, Thailand

phase 2 human trials demonstrated safety and significant levels of immunogenicity; however in October 2020, results of the phase 3 study were published

Retrieved 16 July 2015. Clinical trial number NCT02313077 for "A Safety and Immunogenicity Study of Heterologous Prime-Boost Ebola Vaccine Regimens in Healthy

Nakayama S, Ata K, Nakamura H, et al. (29 June 2022). "Safety and immunogenicity of an inactivated SARS-CoV-2 vaccine, KD-414, in healthy adult and elderly

Descamps, Dominique; Dubin, Gary; HPV Study Group for Adult Women (2009). "Immunogenicity and tolerability of an HPV-16/18 AS04-adjuvanted prophylactic cervical

randomized, double-blind, placebo-controlled trial to evaluate the safety, immunogenicity, and efficacy of an Epstein-Barr virus vaccine in healthy young adults"

Placebo-Controlled Study to Evaluate the Safety, Tolerability, and Immunogenicity of the COVID-19 (SARS-CoV-2) Vaccine Candidates VBI-2902a and VBI-2905a

Yang YK, Du LF, Xu K, Shao S, Liang Y, et al. (June 2022). "Safety and immunogenicity of a hybrid-type vaccine booster in BBIBP-CorV recipients in a randomized

Schneider J; Sarah Gilbert; Blanchard TJ; et al. (1 April 1998). "Enhanced immunogenicity for CD8+ T cell induction and complete protective efficacy of malaria

Vajo Z, Tamas F, Sinka L, Jankovics I (January 2010). "Safety and immunogenicity of a 2009 pandemic influenza A H1N1 vaccine when administered alone

A, Gentile M, Battella S, Lahm A, Sommella A, et al. (April 2021). "Immunogenicity of a new gorilla adenovirus vaccine candidate for COVID-19". Molecular

COVID-19 vaccines for 6 months or longer. "A Study to Evaluate Safety and Immunogenicity of DelNS1-nCoV-RBD LAIV for COVID-19". clinicaltrials.gov. United States

mechanism of action, composition, ease of application, adherence to tissue, immunogenicity and cost. These agents permit rapid hemostasis, better visualization

Chanice; Lall, Paminder; Allen, Lauren (4 September 2021). "Safety and immunogenicity of heterologous versus homologous prime-boost schedules with an adenoviral

four months if experiments show the vaccine does produce effective immunogenicity and provide effective protection against COVID-19. It will be a foundation

The Asian giant hornet (Vespa mandarinia) or northern giant hornet, including the color form referred to as the Japanese giant hornet, is the world's largest

Gasteoenterology Association Fellow 2004 NHMRC Practitioner Fellowship Safety and immunogenicity of human neonatal RV3 rotavirus vaccine (Bio Farma) in adults, children

vaccine against Argentine hemorrhagic fever produced in Argentina. Immunogenicity and safety". Medicina. 70 (3): 215–222. PMID 20529769. Negrón, María

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thermostable anthrax vaccine formulation without compromising on the immunogenicity and its protective potential. The generation of a thermostable anthrax

This is to explore the ability of GRT-R910 to boost and expand the immunogenicity of AstraZeneca's first-generation COVID-19 vaccine AZD1222 (Vaxzevria)

in the dental pulp tissue. Additionally, DPSCs have displayed lower immunogenicity than MSCs. Atari et al., established a protocol for isolating and identifying

Interviewed by Vodovozov A. Retrieved 19 May 2021. "Clinical Trial of Immunogenicity Bridging of a Recombinant New Coronavirus（COVID-19）Vaccine (CHO Cell)"

kills living bone or bone marrow cells. This significantly reduces the immunogenicity (risk of graft rejection) such that no antirejection drugs are needed

hantavirus vaccine (Hantavax). Vaccine. 1999;17:2569–75. "Phase 2a Immunogenicity Study of Hantaan/Puumala Virus DNA Vaccine for Prevention of Hemorrhagic

animal proteins include high biocompatibility, biodegradability, non-immunogenicity, drug loading efficiency, cell uptake, and easy and cost-effective production

focuses on three main aspects: (i) immunogenicity; (ii) cross-reactivity; and (iii) clinical symptoms. Immunogenicity is due to responses of an IgE antibody-producing

administration routes and additional factors on vaccine safety and immunogenicity: a review of recent literature". Expert Review of Vaccines. 13 (3):

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Double-Blind, Placebo-Controlled Phase II Trial Investigating the Safety and Immunogenicity of Modified Vaccinia Ankara Smallpox Vaccine (MVA-BN®) in 56-80-Year-Old

emergency license was based on Phase I and II clinical data of safety and immunogenicity. Gam-COVID-Vac Dolzhikova IV, Tokarskaya EA, Dzharullaeva AS, Tukhvatulin

expressed lower levels of HLA Class I and II, contributing to their lower immunogenicity. Pre-clinical studies performed on the cord lining MSC have revealed

inaccessible for the general population. Drawbacks for ERIG are potential immunogenicity, which is when the immune system recognizes the RIG as foreign and causes

PMID 27036511. "A Phase I Study of the Safety, Reactogenicity, and Immunogenicity of Sm-TSP-2/Alhydrogel® With or Without GLA-AF for Intestinal Schistosomiasis

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Immunogenicity and Efficacy of Non-replicating ChAdOx1 SARS-CoV-2 Vaccine in South African Adults Living Without HIV; and Safety and Immunogenicity in

CR2/CD19 receptor complex of B lymphocytes that mediates the enhanced immunogenicity of C3-bearing antigens, and the counter-regulatory coreceptor, CD22

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tissues and organs will depend on successful strategies to overcome immunogenicity of the manipulated product. Autologous stem-cell transplantation involves

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peptide 2axf: The Immunogenicity of a Viral Cytotoxic T Cell Epitope is controlled by its MHC-bound Conformation 2axg: The Immunogenicity of a Viral Cytotoxic

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find a vaccine, which was published in a 2020 study titled Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report

TCR-exposed residues of MHC-bound peptides is associated with peptide immunogenicity. A native antigen is an antigen that is not yet processed by an APC

research focus is drug mechanisms, therapeutic drug monitoring and immunogenicity of biologics, response to biologic antibody drugs in IBD, and opportunistic

over viral methods, with simple large scale production and low host immunogenicity being just two. Previously, low levels of transfection and expression

M.; Pride, David T.; Kelly, Ciarán P.; Ho, David D. (2016-02-03). "Immunogenicity and protective efficacy of recombinant Clostridium difficile flagellar

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replicating vaccine.: 585  Japan evaluated MVA and rejected it due to its low immunogenicity, deciding to develop its own attenuated vaccine instead. In the 2000s

Reed JL, Noble W, Young NS, Koenig S (February 2003). "Safety and immunogenicity of a recombinant parvovirus B19 vaccine formulated with MF59C.1". The

cell epitopes have been identified and silenced. An RIT with reduced immunogenicity that targets mesothelin expressing cancers is being prepared for clinical

2015-04-15, retrieved 2013-10-28 Brinks, Vera (December 15, 2005), Immunogenicity of biosimilar monoclonal antibodies, Generics and Biosimilars Initiative

dose cohort study to assess safety, tolerability, pharmacokinetics and immunogenicity of GSK1223249 in patients with relapsing forms of multiple sclerosis

Lin AA, Schlom J, June CH, Sherwin SA. Safety, tumor trafficking and immunogenicity of chimeric antigen receptor (CAR)-T cells specific for TAG-72 in colorectal

Eisenlohr LC, Hunt DF, Engelhard VH, Riddell SR (January 2001). "The immunogenicity of a new human minor histocompatibility antigen results from differential

suppresses transplantation responses while minimizing acute toxicity and immunogenicity". Journal of Immunology. 155 (3): 1544–55. doi:10.4049/jimmunol.155

or in part by the Foundation includes: "A mechanism for the specific immunogenicity of heat shock protein-chaperoned peptides" by R Suto, PK Srivastava

Integrative Bioinformatics of Immune Systems Core Nonhuman Primate Immunogenicity Core Pandemic Response Repository through Microbial and Immune Surveillance

Loddenkemper C, Gellermann J, Schmidt K, Wust P, et al. (July 2008). "Immunogenicity of premalignant lesions is the primary cause of general cytotoxic T

Bakker M, Bunge EM, Marano C, de Ridder M, De Moerlooze L (July 2016). "Immunogenicity, effectiveness and safety of combined hepatitis A and B vaccine: a systematic

of the Environment (Tunisia): Chiheb Ben Ahmed:-Humoral and Cellular Immunogenicity of Six Different Vaccines against SARS-CoV-2 in Adults: A Comparative

non-dividing cells, long-term stable expression of a transgene, and low immunogenicity. Lentiviruses have also been successfully used for transduction of diabetic

KL, Alexander WA (July 2009). "A phase 3b, open-label, single-group immunogenicity and safety study of topical recombinant thrombin in surgical hemostasis"

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tissue, properties such as biodegradability, biocompatibility, and immunogenicity must all be carefully considered as they are key factors in the performance

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it to a protein that cuts the DNA rather than binding it. Improving immunogenicity and overcoming self-tolerance: By replacing strategically chosen tyrosines

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tested in animal models and in clinical trials, demonstrating safety and immunogenicity[excessive citations] The success of Okairos led to its acquisition by

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conformational epitopes and self association of such peptides to give high immunogenicity in humans." Chintan Shah 2011 BSc and MSc in Physics Physicist. He currently

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associated with a better prognosis, while treatment may enhance the immunogenicity of the tumour, and hence improve response, although to what extent is

CS1001, modeled after natural immunoglobulin G4 (IgG4), may reduce immunogenicity and other associated toxicities. In May 2024, the Committee for Medicinal

be manipulated and engineered, in addition to their low toxicity and immunogenicity. They have also inspired research into non-cell-based treatment methods

proteases in body fluids and at the same time reduces renal clearance and immunogenicity. The first application described here, deals with the formation of protein-protein

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(MSCs) make them ideal drug delivery vehicles. MSCs also have reduced immunogenicity due to their limited expression of costimulatory molecules. Using MSCs

vivo-like reactions of a human lymph node to analyze, for example, immunogenicity, immune functions and the immunotoxicity of substances. He was the CSO

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in mice and 64 h in cynomolgus monkeys. PEGylation can also decrease immunogenicity and protect a peptide from proteolysis and non-specific adsorption to