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Longer titles found: Thymidine kinase 1 (view), Thymidine kinase 2, mitochondrial (view), Thymidine kinase from herpesvirus (view), Thymidine kinase in clinical chemistry (view), ADP—thymidine kinase (view), AMP—thymidine kinase (view)

searching for Thymidine kinase 45 found (100 total)

alternate case: thymidine kinase

Genetically modified vaccine (86 words) [view diff] exact match in snippet view article find links to article

longer effective. A simple genetically modified vaccine, based on a thymidine kinase deficient mutant of pseudorabies virus was reportedly available as

GL-ONC1 (907 words) [view diff] exact match in snippet view article find links to article

beta-galactosidase, and beta-glucuronidase) into the F14.5L, J2R (encoding thymidine kinase) and A56R (encoding hemagglutinin) loci of the parental viral Lister

Sp4 transcription factor (920 words) [view diff] exact match in snippet view article find links to article

the Sp1 family: interaction with E2F and regulation of the murine thymidine kinase promoter". Journal of Molecular Biology. 293 (5): 1005–15. doi:10.1006/jmbi

Sp2 transcription factor (797 words) [view diff] exact match in snippet view article find links to article

the Sp1 family: interaction with E2F and regulation of the murine thymidine kinase promoter". J. Mol. Biol. 293 (5): 1005–15. doi:10.1006/jmbi.1999.3213

Oncolytic AAV (1,342 words) [view diff] exact match in snippet view article find links to article

AAV-2-TRAIL where combined. AAV-2-HSV-TK: Herpes simplex virus type 1 thymidine kinase (HSV-TK) is a common anti-cancer therapy that converts the ganciclovir

Richard Axel (1,382 words) [view diff] exact match in snippet view article find links to article

Silverstein, S (1978). "The transfer and stable integration of the HSV thymidine kinase gene into mouse cells". Cell. 14 (1): 133–41. doi:10.1016/0092-8674(78)90308-2

TK cell therapy (487 words) [view diff] exact match in snippet view article find links to article

engineering of donor T lymphocytes in order to express a suicide gene (thymidine kinase of the Herpes simplex virus, namely TK) Once the lymphocytes donated

Prototype drug (349 words) [view diff] exact match in snippet view article find links to article

Acyclovir is the prototype antiviral agent that is activated by viral thymidine kinase Aspirin is the prototype NSAID Brophy, Kathleen Marion; Scarlett-Ferguson

Wadsworth Center (648 words) [view diff] exact match in snippet view article find links to article

"Construction of poxviruses as cloning vectors: insertion of the thymidine kinase gene from herpes simplex virus into the DNA of infectious vaccinia

TXNL4B (380 words) [view diff] exact match in snippet view article find links to article

that specifically inhibits growth of herpes simplex virus type 1 thymidine kinase-transduced osteosarcoma cells". J. Biol. Chem. 279 (31): 32832–8. doi:10

Transfection (4,154 words) [view diff] exact match in snippet view article find links to article

Bacchetti S, Graham FL (April 1977). "Transfer of the gene for thymidine kinase to thymidine kinase-deficient human cells by purified herpes simplex viral DNA"

Michael Wigler (2,176 words) [view diff] exact match in snippet view article find links to article

Cheng, Y. and Axel, R. (1977) "Transfer of purified herpes virus thymidine kinase gene to cultured mouse cells." Cell 11: 223-232. PMID 194704; Wigler

Genetically modified mouse (1,707 words) [view diff] exact match in snippet view article find links to article

Senear AW, Warren R, Palmiter RD (1981). "Somatic expression of herpes thymidine kinase in mice following injection of a fusion gene into eggs". Cell. 27 (1

Human artificial chromosome (1,264 words) [view diff] exact match in snippet view article find links to article

Using 21HAC, researchers were able to insert a herpes simplex virus thymidine kinase coding gene into tumor cells. This "suicide gene" is required to activate

DTYMK (493 words) [view diff] exact match in snippet view article find links to article

et al. (1989). "Co-purification of thymidylate kinase and cytosolic thymidine kinase from human term placenta by affinity chromatography". Biochim. Biophys

Frank Bengel (573 words) [view diff] exact match in snippet view article find links to article

in cardiac cells after adenoviral transfer of the herpesvirus thymidine kinase gene: the cellular basis for cardiac gene imaging. Circulation. 2000

Zidovudine (4,932 words) [view diff] exact match in snippet view article find links to article

"Identification and characterization of mitochondrial factors modulating thymidine kinase 2 activity". Nucleosides, Nucleotides & Nucleic Acids. 29 (4–6): 382–385

NFYB (1,235 words) [view diff] exact match in snippet view article find links to article

9.5092. PMC 230756. PMID 7651426. Chang ZF, Liu CJ (1994). "Human thymidine kinase CCAAT-binding protein is NF-Y, whose A subunit expression is serum-dependent

OECD Guidelines for the Testing of Chemicals (152 words) [view diff] case mismatch in snippet view article find links to article

Comet Assay 490 In Vitro Mammalian Cell Gene Mutation Tests Using the Thymidine Kinase Gene 491 Short Time Exposure In Vitro Test Method for Identifying i)

DGUOK (1,023 words) [view diff] exact match in snippet view article find links to article

two patients with novel mutations in the deoxyguanosine kinase and thymidine kinase 2 genes". Mol. Genet. Metab. 84 (1): 75–82. doi:10.1016/j.ymgme.2004

NT5M (818 words) [view diff] exact match in snippet view article find links to article

deoxyribonucleotide pools within mitochondria, in conjunction with the mitochondrial thymidine kinase, as part of the thymidine (dTTP)/dTMP substrate cycle. Since excess

Suicide gene (2,163 words) [view diff] exact match in snippet view article find links to article

commonly studied strategy based on transfection of herpes simplex virus thymidine kinase (HSV-TK) along with administration of ganciclovir (GSV), in which HSK-TK

E2F1 (1,875 words) [view diff] exact match in snippet view article find links to article

the Sp1 family: interaction with E2F and regulation of the murine thymidine kinase promoter". J. Mol. Biol. 293 (5): 1005–15. doi:10.1006/jmbi.1999.3213

Gap junction (10,868 words) [view diff] exact match in snippet view article find links to article

play a role in the 'bystander effect' of the herpes simplex virus thymidine kinase/ganciclovir system in vitro". Gene Ther. 3 (1): 85–92. PMID 8929915

Growth medium (2,206 words) [view diff] exact match in snippet view article find links to article

kill cells that carry its respective marker, the Herpes simplex virus thymidine kinase. Examples of selective media: Eosin methylene blue contains dyes that

Enzo Paoletti (1,293 words) [view diff] exact match in snippet view article find links to article

"Construction of poxviruses as cloning vectors: insertion of the thymidine kinase gene from herpes simplex virus into the DNA of infectious vaccinia

Elizabeth Gavis (769 words) [view diff] exact match in snippet view article find links to article

1981). "Analysis of transcriptional regulatory signals of the HSV thymidine kinase gene: Identification of an upstream control region". Cell. 25 (2):

Griffith R. Harsh (1,283 words) [view diff] exact match in snippet view article find links to article

Silver J, Qureshi N, Kracher J, Finkelstein D, Chiocca A, Hochberg F. Thymidine kinase activation of ganciclovir in recurrent malignant gliomas: A gene marking

Pseudorabies (1,887 words) [view diff] exact match in snippet view article find links to article

transmission to other animals is minimal. In gene-deleted vaccines, the thymidine kinase gene has also been deleted; thus, the virus cannot infect and replicate

Sp3 transcription factor (517 words) [view diff] exact match in snippet view article find links to article

the Sp1 family: interaction with E2F and regulation of the murine thymidine kinase promoter". J. Mol. Biol. 293 (5): 1005–15. doi:10.1006/jmbi.1999.3213

HHV Latency Associated Transcript (1,463 words) [view diff] case mismatch in snippet view article find links to article

the expression of several lytic gene products, including ICP4 and Thymidine Kinase. LAT expression results in changes to Histones, thus converting portions

Fluorodeoxyuridylate (1,304 words) [view diff] exact match in snippet view article find links to article

5-fluoro-2-desoxiuridine (FUdR). Therefore, several cells lines, including thymidine kinase deficient (TK) and thymidylate synthase deficient (TS) were used in

Elephant endotheliotropic herpesvirus (2,828 words) [view diff] exact match in snippet view article find links to article

"Endotheliotropic elephant herpesvirus, the first betaherpesvirus with a thymidine kinase gene". Journal of General Virology. 87 (Pt 10): 2781–2789. doi:10.1099/vir

Herpes simplex research (8,434 words) [view diff] exact match in snippet view article find links to article

case the study uses the transfer of the Herpes simplex virus type I thymidine kinase (HSVtk) as the cytotoxic gene. Hela cells were used in these studies

Ralph L. Brinster (3,974 words) [view diff] exact match in snippet view article find links to article

W., Warren, R., and Palmiter, R. D. Somatic expression of herpes thymidine kinase in mice following injection of a fusion gene into eggs. Cell. 1981;

Virotherapy (3,501 words) [view diff] exact match in snippet view article find links to article

The HSV virus used as an oncolytic virus has retained their native thymidine kinase gene which allows it to be targeted with antiretroviral therapy in

Transcription factor Sp1 (3,446 words) [view diff] exact match in snippet view article find links to article

the Sp1 family: interaction with E2F and regulation of the murine thymidine kinase promoter". Journal of Molecular Biology. 293 (5): 1005–15. doi:10.1006/jmbi

Croton lechleri (2,208 words) [view diff] exact match in snippet view article find links to article

antiviral activity against the aforementioned viruses, as well as thymidine kinase mutants of HSV-1 and HSV-2 and acyclovir-resistant strains. Antidiarrhoeal

Lymphoma in animals (3,371 words) [view diff] exact match in snippet view article find links to article

Selting KA, Sharp CR, Ringold R, Knouse J (December 2015). "Serum thymidine kinase 1 and C-reactive protein as biomarkers for screening clinically healthy

Biological data visualization (6,672 words) [view diff] exact match in snippet view article find links to article

visualization strip (VF) to form an RPA-VF assay that targets the thymidine kinase gene, ensuring fast detection, high specificity, and zero cross-reactivity

Genome evolution (4,940 words) [view diff] exact match in snippet view article find links to article

"Slipping and sliding: frameshift mutations in herpes simplex virus thymidine kinase and drug-resistance". Drug Resistance Updates. 14 (6): 251–259. doi:10

William French Anderson (4,129 words) [view diff] exact match in snippet view article find links to article

Kretschmer, P.J.; Diacumakos, E.G.: Replication and expression of thymidine kinase and human globin genes microinjected into mouse fibroblasts. Proc.

Gene therapy (17,769 words) [view diff] exact match in snippet view article find links to article

treatment of brain tumors using intra-tumoral transduction with the thymidine kinase gene and intravenous ganciclovir". Human Gene Therapy. 4 (1): 39–69

Sanjiv Sam Gambhir (4,744 words) [view diff] exact match in snippet view article find links to article

E.; Herschman, H. R. (2000). "A mutant herpes simplex virus type 1 thymidine kinase reporter gene shows improved sensitivity for imaging reporter gene

Adult neurogenesis (12,661 words) [view diff] exact match in snippet view article find links to article

development of other regions in the brain. The herpes simplex virus thymidine kinase (HSV-TK) has been used in studies in conjunction with antiviral drugs