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searching for E2F1 66 found (116 total)

alternate case: e2F1

SIVA1 (1,004 words) [view diff] exact match in snippet view article find links to article

Siva is a direct transcriptional target for the tumor-suppressors p53 and E2F1. Siva (protein) GRCh38: Ensembl release 89: ENSG00000184990 – Ensembl, May

CCNDBP1 (732 words) [view diff] exact match in snippet view article find links to article

phosphorylation of Rb gene product by cyclin D-dependent protein kinase, and inhibit E2F1-mediated transcription activity. This protein was also found to interact

Mir-17 microRNA precursor family (4,138 words) [view diff] exact match in snippet view article find links to article

(2010). "Aurora kinase A induces miR-17-92 cluster through regulation of E2F1 transcription factor". Cell Mol Life Sci. 67 (12): 2069–76. doi:10.1007/s00018-010-0340-8

Mir-331 microRNA precursor family (340 words) [view diff] exact match in snippet view article find links to article

J, Gu Q, Liu B, Zhu Z, Yu Y (July 2010). "miRNA-331-3p directly targets E2F1 and induces growth arrest in human gastric cancer". Biochemical and Biophysical

Cell cycle hypothesis of Alzheimer's disease (1,732 words) [view diff] exact match in snippet view article find links to article

Additionally, the E2F1 transcription factor in the AD brain is found primarily in the cytoplasm rather than its normal location in the nucleus. E2F1 normally regulates

Mir-330 microRNA precursor family (402 words) [view diff] exact match in snippet view article find links to article

tumor suppressor and induces apoptosis of prostate cancer cells through E2F1-mediated suppression of Akt phosphorylation". Oncogene. 28 (38): 3360–70

Transcription factor DP (117 words) [view diff] exact match in snippet view article find links to article

Pavletich NP (December 2005). "Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release". Cell. 123 (6):

Mir-455 microRNA precursor family (760 words) [view diff] exact match in snippet view article find links to article

HR, Groshong S, Schwartz DA, Yang IV (September 2012). "The role of the E2F1 transcription factor in the innate immune response to systemic LPS". American

Mir-326 microRNA precursor family (774 words) [view diff] exact match in snippet view article find links to article

pituitary GH adenomas: down-regulation of miRNA targeting HMGA1, HMGA2, and E2F1". The Journal of Clinical Endocrinology and Metabolism. 97 (7): E1128-38

Lobianchia (70 words) [view diff] case mismatch in snippet view article find links to article

IRMNG: 1286546 ITIS: 162752 NBN: NHMSYS0019995866 NCBI: 123233 NZOR: 1122e4e3-e2f1-4973-a364-633d3f63e380 Paleobiology Database: 35624 Plazi:

SCF complex (2,021 words) [view diff] case mismatch in snippet view article find links to article

cyclin family proteins: Cyclin D, Cyclin E transcriptional regulators: Myc, E2f1, p130 cyclin-dependent kinase inhibitors (CKIs): p27Kip1, p21, Wee1 centriole

Neuronal cell cycle (2,128 words) [view diff] exact match in snippet view article find links to article

retinoblastoma (Rb) protein and induces the release of the transcription factor E2F1 which is necessary for DNA replication (Liu et al., 1998). The G1/S transition

List of MeSH codes (D12.776.930) (1,091 words) [view diff] no match in snippet view article

The following is a partial list of the "D" codes for Medical Subject Headings (MeSH), as defined by the United States National Library of Medicine (NLM)

DNMT1 (2,381 words) [view diff] exact match in snippet view article find links to article

Wade PA, Jones PL, Wolffe AP (July 2000). "DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters". Nature

GRAMD4 (240 words) [view diff] exact match in snippet view article find links to article

that is encoded by the GRAMD4 gene. GRAMD4 is a mitochondrial effector of E2F1 (MIM 189971)-induced apoptosis. GRCh38: Ensembl release 89: ENSG00000075240

NRIP1 (2,697 words) [view diff] exact match in snippet view article find links to article

visceral adipose tissue. In breast cancer, RIP140 is involved in regulation of E2F1, an oncogene which discriminates between luminal and basal types of tumours

Cyclin E1 (1,720 words) [view diff] exact match in snippet view article find links to article

Nevins JR (1996). "Regulation of the cyclin E gene by transcription factor E2F1". Proc. Natl. Acad. Sci. U.S.A. 92 (26): 12146–50. doi:10.1073/pnas.92.26

CDKN2C (1,270 words) [view diff] exact match in snippet view article find links to article

cyclin-dependent kinase inhibitor p18INK4c by the transcription factors E2F1 and Sp1". J. Biol. Chem. 277 (35): 31679–93. doi:10.1074/jbc.M204554200.

Mir-449 microRNA precursor family (1,227 words) [view diff] exact match in snippet view article find links to article

S2CID 27292546. Feng M, Yu Q (January 2010). "miR-449 regulates CDK-Rb-E2F1 through an auto-regulatory feedback circuit". Cell Cycle. 9 (2): 213–4. doi:10

Trithorax-group proteins (853 words) [view diff] exact match in snippet view article find links to article

1007/s10577-006-1069-y. PMID 16821133. S2CID 19504262. Tyagi S, Herr W (October 2009). "E2F1 mediates DNA damage and apoptosis through HCF-1 and the MLL family of histone

Parachutist Badge (United Kingdom) (706 words) [view diff] exact match in snippet view article

Maquis. Greenhill Books. http://www.raf.mod.uk/rafcms/mediafiles/9647CE1A_E2F1_FD48_EE58A77DCDE87EBE.pdf Archived 24 March 2009 at the Wayback Machine AP

MIRH1 (439 words) [view diff] exact match in snippet view article find links to article

Wentzel EA, Zeller KI, et al. (2005). "c-Myc-regulated microRNAs modulate E2F1 expression". Nature. 435 (7043): 839–43. Bibcode:2005Natur.435..839O. doi:10

CDKN2A (3,317 words) [view diff] exact match in snippet view article find links to article

Therefore, Rb remains associated with transcription factor E2F1, preventing transcription of E2F1 target genes which are crucial for the G1/S transition.

Oncomir (1,974 words) [view diff] exact match in snippet view article find links to article

tumors. The oncomir-1 products inhibit expression of the transcription factor E2F1, which may impact apoptosis via the ARF-p53 pathway. It is predicted that

CDCA7 (584 words) [view diff] exact match in snippet view article find links to article

R, Muramatsu T, et al. (2006). "JPO1/CDCA7, a novel transcription factor E2F1-induced protein, possesses intrinsic transcriptional regulator activity"

XL-413 (248 words) [view diff] exact match in snippet view article find links to article

potential therapeutic target in oral squamous cell carcinoma and is regulated by E2F1". Journal of Molecular Medicine. 96 (6): 513–525. doi:10.1007/s00109-018-1636-7

Protein BTG3 (654 words) [view diff] exact match in snippet view article find links to article

candidate tumor suppressor BTG3 is a transcriptional target of p53 that inhibits E2F1". EMBO J. 26 (17): 3968–80. doi:10.1038/sj.emboj.7601825. PMC 1994125. PMID 17690688

AXIN2 (1,422 words) [view diff] exact match in snippet view article find links to article

doi:10.1074/jbc.M410806200. PMID 15611123. Hughes TA, Brady HJ (2005). "E2F1 up-regulates the expression of the tumour suppressor axin2 both by activation

Mir-432 microRNA precursor family (282 words) [view diff] exact match in snippet view article find links to article

pituitary GH adenomas: down-regulation of miRNA targeting HMGA1, HMGA2, and E2F1". The Journal of Clinical Endocrinology and Metabolism. 97 (7): E1128-38

MIR34A (1,123 words) [view diff] exact match in snippet view article find links to article

ME, Secchiero P (May 2011). "miR-34a induces the downregulation of both E2F1 and B-Myb oncogenes in leukemic cells". Clinical Cancer Research. 17 (9):

PA2G4 (1,255 words) [view diff] exact match in snippet view article find links to article

PMID 12429849. Zhang Y, Woodford N, Xia X, Hamburger AW (April 2003). "Repression of E2F1-mediated transcription by the ErbB3 binding protein Ebp1 involves histone

Phosphoinositide 3-kinase (3,463 words) [view diff] exact match in snippet view article find links to article

"PI3K signaling maintains c-myc expression to regulate transcription of E2F1 in pancreatic cancer cells". Molecular Carcinogenesis. 48 (12): 1149–58.

CDKN2BAS (1,125 words) [view diff] exact match in snippet view article find links to article

implicated in the regulation of nucleus and potential transcriptional target of E2F1". Oncology Reports. 24 (3): 701–707. doi:10.3892/or_00000910. PMID 20664976

CIP2A (1,824 words) [view diff] exact match in snippet view article find links to article

breast cancer cells is defined by positive feedback loop between CIP2A and E2F1". Cancer Discovery. 3 (2): 182–197. doi:10.1158/2159-8290.CD-12-0292. PMC 3572190

The Fifty-Nine Icosahedra (1,341 words) [view diff] case mismatch in snippet view article find links to article

e1f1f2g2 3' 5 6' 7' 9' 10 11 99 99 44 De1f1f2g2 4 5 6' 7' 9' 10 11 99 99 45 e2f1 4' 5' 6 7 9 10 40 Fifteenth stellation 99 Fifteenth stellation of icosahedron

MIR106A (713 words) [view diff] exact match in snippet view article find links to article

Yang B, Zhao S (2011). "MiR-106a inhibits glioma cell growth by targeting E2F1 independent of p53 status". J. Mol. Med. 89 (10): 1037–50. doi:10.1007/s00109-011-0775-x

TP53BP1 (1,857 words) [view diff] exact match in snippet view article find links to article

TJ, Hunt K (Mar 2003). "P202, an interferon-inducible protein, inhibits E2F1-mediated apoptosis in prostate cancer cells". Biochemical and Biophysical

MicroRNA 93 (645 words) [view diff] exact match in snippet view article find links to article

S, Alder H, Ruco LP, Baldassarre G, Croce CM, Vecchione A (March 2008). "E2F1-regulated microRNAs impair TGFbeta-dependent cell-cycle arrest and apoptosis

Low-affinity nerve growth factor receptor (4,235 words) [view diff] exact match in snippet view article find links to article

(January 2004). "Necdin-related MAGE proteins differentially interact with the E2F1 transcription factor and the p75 neurotrophin receptor". The Journal of Biological

Cellular Inhibitor of Apoptosis Protein 1 (1,478 words) [view diff] exact match in snippet view article find links to article

(2011). "Cellular Inhibitor of Apoptosis Protein-1 (cIAP1) Can Regulate E2F1 Transcription Factor-mediated Control of Cyclin Transcription". J Biol Chem

C16orf86 (2,429 words) [view diff] exact match in snippet view article find links to article

cycle from G1 cell to G0. If there is activation, S phase is going to bind E2F1/2/3 with other transcription factors to activate transcription in the cell

DDB2 (2,071 words) [view diff] exact match in snippet view article find links to article

putative DNA repair protein, can function as a transcriptional partner of E2F1". Molecular and Cellular Biology. 18 (1): 240–9. doi:10.1128/mcb.18.1.240

Karen E. Knudsen (1,450 words) [view diff] exact match in snippet view article find links to article

Laere, Bram; Dirix, Luc (January 2018). "Differential impact of RB status on E2F1 reprogramming in human cancer". The Journal of Clinical Investigation. 128

Papillomaviridae (7,242 words) [view diff] exact match in snippet view article find links to article

transcription activator—when interacting with the cellular transcription factor, E2F1/DP1. E6 can also bind to PDZ-domains, short sequences which are often found

HDAC1 (5,476 words) [view diff] exact match in snippet view article find links to article

2003). "A putative coiled-coil domain of prohibitin is sufficient to repress E2F1-mediated transcription and induce apoptosis". Biochemical and Biophysical

Cyclin D (4,605 words) [view diff] exact match in snippet view article find links to article

the G1/S transition (2) allowing Rb dissociation from chromatin, and (3) E2F1 activation. Cyclin D is regulated by the downstream pathway of mitogen receptors

Proliferating cell nuclear antigen (6,161 words) [view diff] exact match in snippet view article find links to article

Drives DNA Anabolism and Proliferation through SRC-3 Phosphorylation and E2F1-Regulated Genes". Cancer Research. 76 (6): 1463–1475. doi:10.1158/0008-5472

Jeffrey Hill (1,460 words) [view diff] exact match in snippet view article find links to article

Kwanmin; Ding, Ling-Wen (2021-03-01). "MNK1 and MNK2 enforce expression of E2F1, FOXM1, and WEE1 to drive soft tissue sarcoma". Oncogene. 40 (10): 1851–1867

Nucleolar and spindle associated protein 1 (573 words) [view diff] exact match in snippet view article find links to article

"Increased expression of NuSAP in recurrent prostate cancer is mediated by E2F1". Oncogene. 32 (1): 70–7. doi:10.1038/onc.2012.27. PMC 3360134. PMID 22349817

C-Raf (8,674 words) [view diff] exact match in snippet view article find links to article

Chellappan S (November 1999). "Rb and prohibitin target distinct regions of E2F1 for repression and respond to different upstream signals". Mol. Cell. Biol

Perilipin-1 (3,315 words) [view diff] exact match in snippet view article find links to article

characterization of the promoter region of perilipin 1 (PLIN1): Roles of E2F1, PLAG1, C/EBPβ, and SMAD3 in bovine adipocytes". Genomics. 112 (3): 2400–2409

Endoreduplication (2,989 words) [view diff] case mismatch in snippet view article find links to article

cycle regulation provided by PIP box- and Cul4Cdt2-mediated destruction of E2f1 during S phase". Developmental Cell. 15 (6): 890–900. doi:10.1016/j.devcel

CDK7 pathway (2,240 words) [view diff] exact match in snippet view article find links to article

unable to bind TFIIH. By contrast, type II activators such as VP16, p53 and E2F1, which supported both initiation and elongation, were able to bind to TFIIH

TP53-inducible glycolysis and apoptosis regulator (3,453 words) [view diff] exact match in snippet view article find links to article

2012). "TIGAR induces p53-mediated cell-cycle arrest by regulation of RB-E2F1 complex". Br. J. Cancer. 107 (3): 516–26. doi:10.1038/bjc.2012.260. PMC 3405207

DNA damage (naturally occurring) (10,148 words) [view diff] exact match in snippet view article

Dick FA (March 2012). "DNA damage signals through differentially modified E2F1 molecules to induce apoptosis". Molecular and Cellular Biology. 32 (5): 900–12

Richard Pestell (2,848 words) [view diff] exact match in snippet view article find links to article

Sakamaki, T.; Albanese, C.; Machii, T.; Pestell, R.G.; Kanakura, Y. (2002). "E2F1 and c-Myc potentiate apoptosis through inhibition of NF-κB activity that

Origin of replication (12,561 words) [view diff] exact match in snippet view article find links to article

origin-specific cis-elements and several protein factors, including the Myb complex, E2F1, and E2F2. This combinatorial specification and multifactorial regulation

STAU1 (2,556 words) [view diff] exact match in snippet view article find links to article

dysregulated in STAU-1 depleted cells. STAU1 was also shown to bind to the 3’UTR of E2F1 mRNA, which played a part in its translation and promotes G1/S transition

Cyclin D/Cdk4 (2,805 words) [view diff] exact match in snippet view article find links to article

Emilie; Chavey, Carine; Iankova, Irena; et al. (2009-07-13). "The CDK4–pRB–E2F1 pathway controls insulin secretion". Nature Cell Biology. 11 (8). Springer

C8orf48 (1,583 words) [view diff] exact match in snippet view article find links to article

org/cgi-bin/carddisp.pl?gene=LRRFIP1". www.genecards.org. Retrieved 2016-05-09. "E2F1 E2F transcription factor 1 [Homo sapiens (human)] - Gene - NCBI". www.ncbi

MECOM (4,864 words) [view diff] exact match in snippet view article find links to article

proliferation by interacting with BRG1 and blocking the repression of BRG1 on E2F1 activity". The Journal of Biological Chemistry. 278 (50): 49806–11. doi:10

Epigenetics and melanoma (2,898 words) [view diff] exact match in snippet view article find links to article

Zeller KI, Dang CV, Mendell JT. 2005. "c-Myc-regulated microRNAs modulate E2F1 expression". Nature. Vol 435, issue 7043:839–43. He L, Thomson JM, Hemann

Circular RNA (6,557 words) [view diff] exact match in snippet view article find links to article

Overexpression of circFOXO3 and its downregulation binds to the transcription factors E2F1, HIF1α and protein ID1, FAK, causing cardiomyopathy induced by DOX. Titin

TMEM39B (2,517 words) [view diff] exact match in snippet view article find links to article

family bHLH transcription factor 1 0.99 OSR2 Odd-skipped related 2 0.99 E2F1 E2F transcription factor 1 0.989 ZNF35 Human zinc finger protein ZNF35 0

Ankur Singh (2,644 words) [view diff] exact match in snippet view article find links to article

germinal centre formation through epigenetic silencing of CDKN1A and an Rb-E2F1 feedback loop". Nature Communications. 8 (1): 877. Bibcode:2017NatCo...8

List of human transcription factors (81 words) [view diff] exact match in snippet view article find links to article

specific TF according to literature or domain structure – No motif [170] E2F1 ENSG00000101412 E2F Known motif – High-throughput in vitro [171] WTTGGCGCCHWW