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searching for Cyclin E1 8 found (19 total)

alternate case: cyclin E1

Cyclin E/Cdk2 (1,334 words) [view diff] exact match in snippet view article find links to article

promote entry into S phase. Eukaryotic cells possess two types of cyclin, cyclin E1 and cyclin E2, with the protein sequences sharing 69.3% similarity in

Palbociclib (3,559 words) [view diff] exact match in snippet view article find links to article

Palbociclib is less effective in patients whose breast cancer cells overexpress cyclin E1 or E2, and Brk (breast tumor-related kinase). Brk is an intracellular

Ovarian clear-cell carcinoma (968 words) [view diff] exact match in snippet view article find links to article

receptors and Wilm tumor suppressor 1. The CCNE1 gene encodes for the cyclin E1 protein which accumulates at the G1-S phase transition point of the cell

MIR195 (698 words) [view diff] exact match in snippet view article find links to article

M, Yoshizato K, Ikeda K, Kawada N (October 2011). "Down-regulation of cyclin E1 expression by microRNA-195 accounts for interferon-β-induced inhibition

Louise Johnson (1,406 words) [view diff] exact match in snippet view article find links to article

V.; Cook, A.; Brown, N. R.; Johnson, L. N. (2005). "The structure of cyclin E1/CDK2: Implications for CDK2 activation and CDK2-independent roles". The

CDK inhibitor (2,633 words) [view diff] exact match in snippet view article find links to article

harboring KRAS mutations resulted in upregulation of cyclin D1, CDK4, and cyclin E1, negating the effects of administering the drug. Malumbres et al., categorized

Basal-like carcinoma (1,741 words) [view diff] exact match in snippet view article find links to article

of transcription factors (inducing CyclinE expression). Additionally, Cyclin E1 is more easily replicated in BLBC than other types of breast cancer, and

Neuronal cell cycle (2,128 words) [view diff] exact match in snippet view article find links to article

may regulate the activation of cell cycle progression by upregulating cyclin E1 and downregulating p27Kip1 (Busser et al., 1998; Yang et al., 2003). Alzheimer