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Longer titles found: Gene therapy for color blindness (view), Gene therapy for epilepsy (view), Gene therapy for osteoarthritis (view), Gene therapy in Parkinson's disease (view), Gene therapy of the human retina (view), Vectors in gene therapy (view), Lentiviral vector in gene therapy (view), Retinal gene therapy using lentiviral vectors (view), Current Gene Therapy (view), Center for Cell and Gene Therapy (view), 2002 French gene therapy trials (view), Bespoke Gene Therapy Consortium (view), Congenital Blindness Gene Therapy (view)

searching for Gene therapy 194 found (1450 total)

alternate case: gene therapy

Molecular cloning (3,953 words) [view diff] exact match in snippet view article find links to article

“germ line gene therapy” is considered by many to be unethical in human beings. The second type of gene therapy, “somatic cell gene therapy”, is analogous
List of Nature Research journals (629 words) [view diff] case mismatch in snippet view article find links to article
Bone Research British Dental Journal British Journal of Cancer Cancer Gene Therapy Cell Death & Disease Cell Death & Differentiation Cell Death Discovery
Ultragenyx (824 words) [view diff] exact match in snippet view article find links to article
Dimension Therapeutics in 2017 to obtain adeno-associated virus (AAV)-based gene therapy manufacturing technology. The company's recent research and development
Maple syrup urine disease (3,002 words) [view diff] exact match in snippet view article find links to article
descent. Gene therapy to overcome the genetic mutations that cause MSUD have already been proven safe in animals studies with MSUD. The gene therapy involves
Thymidine kinase (11,061 words) [view diff] exact match in snippet view article find links to article
kinase-based suicide gene therapy for malignant glioma--an alternative for Herpes Simplex virus-1 thymidine kinase". Cancer Gene Therapy. 22 (3): 130–7. doi:10
Telomerase reverse transcriptase (5,294 words) [view diff] exact match in snippet view article find links to article
aging in human fibroblasts. The hTERT gene has become a main focus for gene therapy involving cancer due to its expression in tumor cells but not somatic
Molecular Therapy (69 words) [view diff] case mismatch in snippet view article find links to article
- Elsevier". "Salk Scientist Inder Verma to Receive 2009 Outstanding Achievement Award from American Society of Gene Therapy". Official website v t e
BioDrugs (48 words) [view diff] no match in snippet view article find links to article
BioDrugs is a peer-reviewed pharmacology journal. BioDrugs covers the development and therapeutic application of biotechnology-based pharmaceuticals and
Flexion Therapeutics (603 words) [view diff] exact match in snippet view article find links to article
osteoarthritis-related knee pain. In December 2017, Flexion acquired an investigational gene therapy product candidate for the treatment of osteoarthritis (OA), known as
Sangamo Therapeutics (781 words) [view diff] exact match in snippet view article find links to article
biotechnology company based in Brisbane, California. It applies cell and gene therapy to combat haemophilia and other genetic diseases. The company was founded
Feline foamy virus (1,223 words) [view diff] exact match in snippet view article find links to article
Virus. However, ongoing studies are exploring the role of FeFV in viral gene therapy to treat other pathogenic feline diseases. Felines with FeFV often live
Restriction modification system (2,558 words) [view diff] exact match in snippet view article find links to article
PMID 27140615. Wayengera M (2003). "HIV and Gene Therapy: The proposed [R-M enzymatic] model for a gene therapy against HIV". Makerere Med J. 38: 28–30.
Feline foamy virus (1,223 words) [view diff] exact match in snippet view article find links to article
Virus. However, ongoing studies are exploring the role of FeFV in viral gene therapy to treat other pathogenic feline diseases. Felines with FeFV often live
HIV/AIDS research (3,759 words) [view diff] exact match in snippet view article find links to article
a biotechnology company with a first-in-human CRISPR-based one-time gene therapy to be evaluated in individuals with HIV. Research Foundation to Cure
Mitochondrial disease (3,136 words) [view diff] exact match in snippet view article find links to article
gov # NCT02161380) to examine the safety and efficacy of mitochondrial gene therapy in Leber's hereditary optic neuropathy. About 1 in 4,000 children in
Human artificial chromosome (1,262 words) [view diff] exact match in snippet view article find links to article
cells. This research opens a variety of opportunities for using HACs in gene therapy. In 2011, researchers formed a human artificial chromosome by truncating
Restriction modification system (2,558 words) [view diff] exact match in snippet view article find links to article
PMID 27140615. Wayengera M (2003). "HIV and Gene Therapy: The proposed [R-M enzymatic] model for a gene therapy against HIV". Makerere Med J. 38: 28–30.
Cystic Fibrosis Trust (589 words) [view diff] exact match in snippet view article find links to article
two main categories: Gene therapy – The Trust currently invests over £3 million a year in a programme of research into gene therapy, in order to make it
Zinc finger nuclease (4,644 words) [view diff] case mismatch in snippet view article find links to article
PMID 21912434. Carroll D (2008). "Zinc-finger Nucleases as Gene Therapy Agents". Gene Therapy. 15 (22): 1463–1468. doi:10.1038/gt.2008.145. PMC 2747807
Mantle cell lymphoma (3,459 words) [view diff] case mismatch in snippet view article find links to article
source, which is in the public domain. "FDA Approves First Cell-Based Gene Therapy For Adult Patients with Relapsed or Refractory MCL". U.S. Food and Drug
Insertional mutagenesis (1,031 words) [view diff] exact match in snippet view article find links to article
Some DNA insertions will lead to no noticeable mutation. In recent gene therapy trials, the lentiviral vectors used to insert therapeutic DNA showed
Oregon Health and Science University Center for Women's Health (638 words) [view diff] exact match in snippet view article find links to article
Heroines". pdx.edu. Retrieved April 15, 2015. "Researchers test new gene therapy method in human cells...and it works". sciguru.org. Retrieved April 15
Mark Wainberg (721 words) [view diff] exact match in snippet view article find links to article
reverse transcriptase, the molecular basis for drug resistance, and gene therapy. He received a B.Sc. from McGill University in 1966, a Ph.D. from Columbia
Society for Hematology and Stem Cells (281 words) [view diff] exact match in snippet view article find links to article
application of basic hematology, immunology, stem cell research, cell and gene therapy and related aspects of research through publications, discussions, scientific
Prevention of HIV/AIDS (6,637 words) [view diff] exact match in snippet view article find links to article
K, Cathomen T (2015). "Editing CCR5: a novel approach to HIV gene therapy". Gene Therapy for HIV and Chronic Infections. Advances in Experimental Medicine
Oncolytic herpes virus (1,828 words) [view diff] case mismatch in snippet view article find links to article
early development of these was thoroughly reviewed in the journal Cancer Gene Therapy in 2002. This page describes (in the order of development) the most notable
Hearing loss (10,124 words) [view diff] exact match in snippet view article find links to article
the signals from hair cells to the brain. A 2008 study has shown that gene therapy targeting Atoh1 can cause hair cell growth and attract neuronal processes
Canavan disease (1,870 words) [view diff] exact match in snippet view article find links to article
as supportive therapy for children with Canavan disease. Experimental gene therapy trial results, published in 2002, used a healthy gene to take over for
Richard C. Mulligan (249 words) [view diff] case mismatch in snippet view article find links to article
Professor of Genetics at Harvard Medical School, and Director of the Harvard Gene Therapy Initiative. He is a Director of Enzon Pharmaceuticals, Inc., and Biogen
Coding region (2,486 words) [view diff] exact match in snippet view article find links to article
This can further assist in mapping the human genome and developing gene therapy. Although this term is also sometimes used interchangeably with exon
University of Navarra (778 words) [view diff] case mismatch in snippet view article find links to article
four main areas: Oncology, Neuroscience, Cardiovascular Sciences, and Gene Therapy and Hepatology. The institution was founded as the Estudio General de
WuXi AppTec (844 words) [view diff] exact match in snippet view article find links to article
and manufacturing, biologics R&D and manufacturing, cell therapy and gene therapy R&D and manufacturing, medical device testing, and molecular testing
Human foamy virus (1,315 words) [view diff] exact match in snippet view article find links to article
pathogenic in humans and is a retrovirus, it is an ideal vector for gene therapy. Another important feature of the virus is that the Gag, Pol, and Env
James Wilson (scientist) (687 words) [view diff] exact match in snippet view article
James M. Wilson is a biomedical researcher with expertise in gene therapy. Wilson graduated from Albion College (B.A., Chemistry) and the University of
Sarepta Therapeutics (1,078 words) [view diff] exact match in snippet view article find links to article
Sarepta acquired five gene therapy candidates for $165 million after one of them, MYO-101, produced results with a new gene therapy candidate for patients
Leukocyte adhesion deficiency-1 (333 words) [view diff] exact match in snippet view article find links to article
been cloned and sequenced, this disorder is a potential candidate for gene therapy. As of 2010[update], LAD1 has been observed in several hundred children
Sims (novel) (235 words) [view diff] exact match in snippet view article
future, there have been amazing advances in genetics research. Through gene therapy, many deadly diseases have been cured. The SimGen Corporation has created
Bleeding diathesis (791 words) [view diff] exact match in snippet view article find links to article
Bernard–Soulier syndrome, Wiskott–Aldrich syndrome and Glanzmann's thrombasthenia. Gene therapy treatments may be a solution as they involve in the insertion of normal
Transposase (2,457 words) [view diff] exact match in snippet view article find links to article
is used primarily in vertebrate animals for gene transfer, including gene therapy, and gene discovery. The engineered SB100X is an enzyme that directs
Adverum Biotechnologies (493 words) [view diff] exact match in snippet view article find links to article
Avalanche Biotechnologies, is a publicly traded (NASDAQ:ADVM) clinical stage gene therapy company located in Redwood City, California. The company is targeting
Hertz Nazaire (342 words) [view diff] exact match in snippet view article find links to article
Sickle-cell disease around the world, and supports the use of CRISPR for gene therapy. He is also a published author of an adult coloring book series titled
Protamine sulfate (936 words) [view diff] exact match in snippet view article find links to article
purification and in tissue cultures as a crosslinker for viral transduction. In gene therapy, protamine sulfate has been studied as a means to increase transduction
George Stamatoyannopoulos (356 words) [view diff] exact match in snippet view article find links to article
felt that the American Society of Human Genetics did not fully discuss gene therapy. In 2004, he was made a fellow of the American Academy of Arts and Sciences
Beckman Research Institute (1,877 words) [view diff] exact match in snippet view article find links to article
Lentiviral vectors for delivering RNA-based gene therapy. This approach combines stem cell and gene therapy to deliver RNA molecules that can block the
Sperm-mediated gene transfer (1,053 words) [view diff] exact match in snippet view article find links to article
models for human diseases or lead to future discoveries relating to human gene therapy. The method for SMGT uses the sperm cell, a natural vector of genetic
Centennial Biomedical Campus of North Carolina State University (454 words) [view diff] exact match in snippet view article find links to article
Translational Research and houses research activities in genomic sciences, gene therapy, vaccine development, creation of diagnostic tests, new cancer immuno-therapy
Mavis Agbandje-McKenna (2,705 words) [view diff] exact match in snippet view article find links to article
AAV capsids has led to the development of viral capsid development and gene therapy approaches that evade immune detection and can be used to treat human
Acute lymphoblastic leukemia (7,745 words) [view diff] exact match in snippet view article find links to article
of the Commissioner. "Press Announcements—FDA approval brings first gene therapy to the United States". www.fda.gov. Archived from the original on 3 September
Urbach–Wiethe disease (2,458 words) [view diff] exact match in snippet view article find links to article
discovery of the mutations of the ECM1 gene has opened the possibility of gene therapy or a recombinant ECM1 protein for Urbach–Wiethe disease treatment, but
Mavis Agbandje-McKenna (2,705 words) [view diff] exact match in snippet view article find links to article
AAV capsids has led to the development of viral capsid development and gene therapy approaches that evade immune detection and can be used to treat human
Angiogenesis inhibitor (2,901 words) [view diff] exact match in snippet view article find links to article
, Celec, P., & Li, C. J. (2011). Gene therapy for cancer: bacteria-mediated anti-angiogenesis therapy. Gene therapy, 18(5), 425-431. Xu, Y. F., Zhu, L
Milomir Kovac (865 words) [view diff] exact match in snippet view article find links to article
(Great Britain), was the first in the world to successfully apply the gene therapy technology in the treatment of severe damage of equine tendon and ligaments
Elizabeth Rakoczy (530 words) [view diff] exact match in snippet view article find links to article
Institute. In 2017, Rakoczy was awarded the Florey Medal for her human gene therapy trial to modify viruses for the treatment of wet age-related macular
Genetic Information Research Institute (257 words) [view diff] exact match in snippet view article find links to article
the genetic makeup of different organisms, as a basis for potential gene therapy and genome engineering techniques." The institute specializes in applying
Progenitor cell (1,304 words) [view diff] exact match in snippet view article find links to article
ISBN 978-1-60535-470-5. OCLC 945169933. Boccardi V, Herbig U (August 2012). "Telomerase gene therapy: a novel approach to combat aging". EMBO Molecular Medicine. 4 (8): 685–7
Shaf Keshavjee (1,429 words) [view diff] exact match in snippet view article find links to article
preservation. His current studies examine molecular diagnostics and gene therapy strategies for engineering organs for lung transplantation. The Lab's
Jeff Lyon (335 words) [view diff] exact match in snippet view article find links to article
[the seven part ‘Altered Fates, The Promise of Gene Therapy’ 1986] series on the promises of gene therapy, which examined the implications of this revolutionary
Nuria Martí Gutiérrez (555 words) [view diff] case mismatch in snippet view article find links to article
currently a senior research associate at the Center for Embryonic Cell and Gene Therapy at Oregon Health & Science University (OHSU). She received her bachelors
Beverly Davidson (757 words) [view diff] exact match in snippet view article find links to article
Children's Hospital of Philadelphia. In this role, she investigates gene therapy for neurodegenerative diseases, specifically Huntington's. In 2019, Davidson
Simon J. Hall (1,189 words) [view diff] case mismatch in snippet view article find links to article
and. Conley BA. Gene Therapy for the Treatment of Cancer, In Kresina TF (Ed.), An Introduction to Molecular Medicine and Gene Therapy, John Wiley & Sons
Expert Review of Hematology (233 words) [view diff] exact match in snippet view article find links to article
research – in areas such as immunology, stem cell research, and cell and gene therapy – into the clinical context. Each review includes an ‘expert commentary’
Fabry disease (3,431 words) [view diff] exact match in snippet view article find links to article
forward into active site specific chaperones. Besides these drugs, a gene therapy treatment is in clinical trials, with the technology licensed to AvroBio
PTC Therapeutics (587 words) [view diff] exact match in snippet view article find links to article
focused on the development of orally administered small molecule drugs and gene therapy which regulate gene expression by targeting post-transcriptional control
Protamine (2,034 words) [view diff] exact match in snippet view article find links to article
been isolated. An analogue of this peptide has also been produced. In gene therapy, protamine sulfate's ability to condense plasmid DNA along with its approval
Paul A. Sieving (921 words) [view diff] exact match in snippet view article find links to article
developed a mouse model of XLRS and successfully treated the condition by gene therapy in mouse and rabbit models.  Sieving's team, in coordination with the
Arthur Caplan (3,435 words) [view diff] exact match in snippet view article find links to article
bioethicist to be sued for his professional role, after his involvement in a gene therapy trial that resulted in the death of research subject Jesse Gelsinger
Deborah Nelson (1,172 words) [view diff] exact match in snippet view article find links to article
Her news publications also have addressed issues of misconduct in the gene therapy field and medical research in developing countries. In 1997, Deborah
Enadenotucirev (368 words) [view diff] exact match in snippet view article find links to article
additional genes using the tumor-specific immuno-gene therapy (T-SIGn) platform to develop novel cancer gene therapy agents. The T-SIGn vectors at clinical study
Axovant Sciences (806 words) [view diff] exact match in snippet view article find links to article
Pavan Cheruvu became the new CEO. In December 2018, Axovant added two gene therapy programs[which?] to treat GM1 gangliosidosis and Tay–Sachs and Sandhoff
Leonard W. Seymour (363 words) [view diff] case mismatch in snippet view article find links to article
Leonard W. Seymour is Professor of Gene Therapy within the University of Oxford's oncology division. As a cancer-oriented translational researcher, he
Orthodontics (3,391 words) [view diff] exact match in snippet view article find links to article
malocclusions are mild. Biology of tooth movement and how advances in gene therapy and molecular biology technology may shape the future of orthodontic
Beta adrenergic receptor kinase carboxyl-terminus (839 words) [view diff] exact match in snippet view article find links to article
located in the plasma membrane of cells. It is currently an experimental gene therapy for the treatment of heart failure. During heart failure, the heart is
Theodore Friedmann (315 words) [view diff] exact match in snippet view article find links to article
16, 1935) is an American researcher most noted for his work in human gene therapy. Friedmann received his A.B in 1956 and M.D. in 1960 from the University
Roger D. Cone (249 words) [view diff] exact match in snippet view article find links to article
Massachusetts Institute of Technology in 1985 under the mentorship of the gene therapy pioneer Richard C. Mulligan. He is largely cited in his field. In 2008
Max Cynader (765 words) [view diff] exact match in snippet view article find links to article
cofounded NeuroVir, a Vancouver-based biotechnology company which developed gene therapy products to treat brain diseases. This company, which grew to over 60
Endogenous retrovirus (7,096 words) [view diff] exact match in snippet view article find links to article
and with other endogenous DNA sequences, it would be beneficial for gene therapy to explore the potential risks HERVs can cause, if any. Also, this ability
Expression cassette (365 words) [view diff] case mismatch in snippet view article find links to article
and Control Elements: Designing Expression Cassettes for Gene Therapy". Current Gene Therapy. 4 (4): 89–113. CiteSeerX 10.1.1.494.3472. doi:10.2174/1566523044578077
Barth syndrome (2,119 words) [view diff] exact match in snippet view article find links to article
Syndrome". Human Gene Therapy. 30 (2): 139–154. doi:10.1089/hum.2018.020. ISSN 1043-0342. PMC 6383582. PMID 30070157. "Gene therapy for heart, skeletal
Victor Dzau (728 words) [view diff] exact match in snippet view article find links to article
He pioneered gene therapy for vascular disease, being the first to introduce DNA decoy molecules to block transcriptions as gene therapy in humans. Dzau's
Thomas Chang (422 words) [view diff] exact match in snippet view article find links to article
years ahead of the modern era of nanotechnology, regenerative medicine, gene therapy, stem cell/cell therapy and blood substitutes. Evidence of his stature
Vascular endothelial growth factor A (3,053 words) [view diff] exact match in snippet view article find links to article
formation and increased the viability of the cells in that area. In gene therapy, DNA which encodes the gene of interest is integrated into a vector along
Astellas Pharma (2,165 words) [view diff] exact match in snippet view article find links to article
into Gene Therapy". BioSpace (in American English). Retrieved 2020-04-21. "Japan's Astellas to buy Audentes for $3 billion in high-priced gene therapy bet"
Meganuclease (2,295 words) [view diff] exact match in snippet view article find links to article
elimination of viral genetic material or the "repair" of damaged genes using gene therapy. Meganucleases are found in a large number of organisms – Archaea or
Helen Heslop (628 words) [view diff] case mismatch in snippet view article find links to article
Baylor College of Medicine and the director of the Center for Cell and Gene Therapy at Baylor College of Medicine, Texas Children’s Hospital and Houston
Recombinant AAV mediated genome engineering (2,671 words) [view diff] exact match in snippet view article find links to article
nature of rAAV, it has emerged as a desirable vector for performing gene therapy in live patients. The rAAV genome is built of single-stranded deoxyribonucleic
X-linked myotubular myopathy (580 words) [view diff] exact match in snippet view article find links to article
[citation needed] Audentes Therapeutics is developing an experimental gene therapy to treat the condition. A clinical trial was halted in 2020 after two
Markus Grompe (325 words) [view diff] exact match in snippet view article find links to article
have been used to model diseases such as malaria and to optimize human gene therapy strategies Dr. Grompe has made major contributions to the study of Fanconi
Burdwan Medical College and Hospital (1,626 words) [view diff] no match in snippet view article find links to article
Burdwan Medical College and Hospital is a public hospital and medical research institute located in Burdwan Town, Purba Bardhaman district, West Bengal
Steel (John Henry Irons) (7,149 words) [view diff] exact match in snippet view article
that he had been injected with a small dosage of Lex Luthor's new exo-gene therapy, causing his skin to mutate into stainless steel and back again. He returned
Doping (151 words) [view diff] exact match in snippet view article find links to article
autonomic dysreflexia Gene doping, the hypothetical non-therapeutic use of gene therapy by athletes Stem cell doping Technology doping Doping in China Doping
Factor VIII (medication) (691 words) [view diff] exact match in snippet view article
medical costs for people with hemophilia. They are so expensive that gene therapy for haemophilia might be less expensive, especially for people with severe
Combinatorial ablation and immunotherapy (1,180 words) [view diff] exact match in snippet view article find links to article
heat shock protein promoter-controlled HSV-TK gene therapy: Toward imaging-guided interventional gene therapy". Oncotarget. 7 (40): 65042–65051. doi:10.18632/oncotarget
Transplant engineering (352 words) [view diff] case mismatch in snippet view article find links to article
Thomas K. (2009-10-28). "Functional Repair of Human Donor Lungs by IL-10 Gene Therapy". Science Translational Medicine. 1 (4): 4ra9. doi:10.1126/scitranslmed
Calpainopathy (958 words) [view diff] exact match in snippet view article find links to article
Research is being done to identify the proteins cleaved by calpain-3. Gene therapy is being studied to replace the function of the calpain-3. Injection
Gustav Gaudernack (2,244 words) [view diff] case mismatch in snippet view article find links to article
with dendritic cells transfected with autologous tumor-mRNA". Cancer Gene Therapy. 13 (10): 905–18. doi:10.1038/sj.cgt.7700961. PMID 16710345. Kyte, Jon
Great Ormond Street Hospital for Children NHS Foundation Trust (1,137 words) [view diff] no match in snippet view article find links to article
the UK. Recent[update] high-profile breakthroughs include successful gene-therapy for immune diseases. The trust is a member of the UCL Partners academic
Jonathan Simons (1,166 words) [view diff] exact match in snippet view article find links to article
Simons’ clinical team took the biotechnology into the world’s first human gene therapy clinical trials for advanced prostate cancer at Johns Hopkins. Simons
CCR5 (7,652 words) [view diff] exact match in snippet view article find links to article
Nazari R, Joshi S (Aug 2008). "CCR5 as target for HIV-1 gene therapy". Current Gene Therapy. 8 (4): 264–72. doi:10.2174/156652308785160674. PMID 18691022
Désiré Collen (5,230 words) [view diff] case mismatch in snippet view article find links to article
Vascular Biology) and the VIB Department for Transgene Technology and Gene Therapy (now VIB-KU Leuven Center for Cancer Biology). He authored and co-authored
ProSavin (265 words) [view diff] exact match in snippet view article find links to article
"Long-term safety and tolerability of ProSavin, a lentiviral vector-based gene therapy for Parkinson's disease: a dose escalation, open-label, phase 1/2 trial"
MYH6 (2,959 words) [view diff] exact match in snippet view article find links to article
ineffective. Gene therapy is currently being investigated as a possible treatment option. Myh6 gene is a possible target for gene therapy. Infected with
Jesús Prieto (719 words) [view diff] case mismatch in snippet view article find links to article
University of Navarra and Director of the Division of Hepatology and Gene Therapy of the Center for Applied Medical Research (CIMA). Since 2014 he is Emeritus
Myelitis (2,486 words) [view diff] exact match in snippet view article find links to article
enzymatic reaction. Biochemical repair Neurotropic factor therapy and gene therapy Neurotropic growth factors regulate growth, survival, and plasticity
Occult macular dystrophy (1,464 words) [view diff] exact match in snippet view article find links to article
approach would need to be developed for gene therapy to treat OMD. Since RP1 has the same size problem, a gene therapy for RP could have a spillover effect
Jay Neitz (448 words) [view diff] exact match in snippet view article find links to article
some attention in the popular science press. In this work, they gave gene therapy to two red-green color-blind squirrel monkeys, combined with training
Margaret Goodell (1,066 words) [view diff] case mismatch in snippet view article find links to article
College of Medicine since 1997 as a member of the Center for Cell and Gene Therapy, and the Departments of Pediatrics, Molecular and Human Genetic, and
Amit Patel (708 words) [view diff] exact match in snippet view article find links to article
of heart surgery and burns. He is also the founder of Xogenex LLC, a gene therapy company for heart failure. The project is code-names the "Bourne-Project"
Derek Crowther (192 words) [view diff] case mismatch in snippet view article find links to article
College, Cambridge. He was a member of the United Kingdom government's Gene Therapy Advisory Committee, which first convened in November 1993. In June 2015
Robert Williamson (physician) (1,688 words) [view diff] exact match in snippet view article
(APP). Williamson was an early proponent of human gene therapy, writing presciently in 1982: "Gene therapy is not yet possible, but may become feasible soon
Ofranergene obadenovec (315 words) [view diff] exact match in snippet view article find links to article
Ofranergene obadenovec, also known as VB-111, is an anti-angiogenic gene therapy. The vector is a non-replicating adenovirus 5. The payload is a chimeric
Michael Tomczyk (2,057 words) [view diff] exact match in snippet view article find links to article
also written book chapters and articles on the future of biosciences, gene therapy and medical innovations. During his career, he has studied and developed
Foundation Fighting Blindness (1,346 words) [view diff] exact match in snippet view article find links to article
funds research in a number of scientific areas including: genetics, gene therapy, nutrition, stem cells, and pharmaceutical therapies. After decades of
Jeans for Genes (550 words) [view diff] exact match in snippet view article find links to article
Chronic Granulomatous Disease (CGD) for his son and other CGD boys through gene therapy. This relatively new form of treatment still remains the greatest creator
Lymphocyte expansion molecule (145 words) [view diff] exact match in snippet view article find links to article
for drug discovery. Scientists at Imperial College are developing a gene therapy based on this protein. Knapton, Sarah (16 April 2015). "Scientists find
Novartis (10,678 words) [view diff] exact match in snippet view article find links to article
acquire Vedere Bio for $280 million boosting the businesses cell and gene therapy offerings. In October 2020, as part of a joint venture to develop therapeutic
Biogen (3,312 words) [view diff] exact match in snippet view article find links to article
progression. Biogen also has since 2015 an agreement with AGTC to develop gene therapy for several genetic diseases, including X-linked retinoschisis (XLRS)
Reza Dana (2,022 words) [view diff] exact match in snippet view article find links to article
promote corneal endothelial cell survival in transplantation, including gene therapy. 1981 – National Cum Laude Society 1984 – Phi Beta Kappa (Junior Year)
Genetics in fiction (2,601 words) [view diff] exact match in snippet view article find links to article
implications; the production company, Sony Pictures, consulted with a gene therapy researcher, French Anderson, to ensure that the portrayal of science
Avantor (936 words) [view diff] exact match in snippet view article find links to article
center in Shanghai, which focuses on monoclonal antibodies and cell and gene therapy. In 2020, Avantor doubled the size of its Bridgewater, New Jersey innovation
Lymphocyte expansion molecule (145 words) [view diff] exact match in snippet view article find links to article
for drug discovery. Scientists at Imperial College are developing a gene therapy based on this protein. Knapton, Sarah (16 April 2015). "Scientists find
Avantor (936 words) [view diff] exact match in snippet view article find links to article
center in Shanghai, which focuses on monoclonal antibodies and cell and gene therapy. In 2020, Avantor doubled the size of its Bridgewater, New Jersey innovation
Alicia Bertone (2,119 words) [view diff] exact match in snippet view article find links to article
regarding comparative orthopedic medicine, regenerative medicine, and gene therapy for the treatment of cartilage injury and bone repair. She is affiliated
Ferring Pharmaceuticals (1,858 words) [view diff] exact match in snippet view article find links to article
joint investment of over $570 million USD in an investigational novel gene therapy in late stage development for patients with high-grade, Bacillus Calmette-Guérin
Ribozyme (5,145 words) [view diff] exact match in snippet view article find links to article
have been proposed and developed for the treatment of disease through gene therapy (3). One major challenge of using RNA based enzymes as a therapeutic
Cedars-Sinai Medical Center (6,637 words) [view diff] exact match in snippet view article find links to article
Cedars-Sinai has research centers covering cardiovascular, genetics, gene therapy, gastroenterology, neuroscience, immunology, surgery, organ transplantation
Saving Eliza (393 words) [view diff] exact match in snippet view article find links to article
researchers at Nationwide Children's Hospital, in Columbus, Ohio, had found a gene therapy that worked on mice, but they would need an additional $2.5 million to
Amino acid N-carboxyanhydride (1,968 words) [view diff] exact match in snippet view article find links to article
in the field of biomaterials for their applications in drug delivery, gene therapy, antibiotics, and tissue engineering. Typically, these compounds are
Stargate Atlantis (season 5) (502 words) [view diff] exact match in snippet view article
with another hive and its Queen in order to get the Wraith to use a new gene therapy to eliminate their need to feed. It's not too long before suspicion is
Immunogenetics (739 words) [view diff] exact match in snippet view article find links to article
genetic dispositions and how these dispositions can be affected by agents (gene therapy). A special focus is often laid on the forecast regarding and therapy
Mason-Pfizer monkey virus (2,420 words) [view diff] exact match in snippet view article find links to article
the target cells aids the facilitation of the nuclear export for the gene therapy. Mason-Pfizer monkey virus (M-PMV) derived from breast tumor tissue of
GUIDE-Seq (831 words) [view diff] exact match in snippet view article find links to article
insert that preferentially integrates into double-stranded breaks. As gene therapy is an emerging field, GUIDE-Seq has gained traction as a cheap method
Restriction enzyme (5,834 words) [view diff] exact match in snippet view article find links to article
PMID 24597865. Wayengera M (2003). "HIV and Gene Therapy: The proposed [R-M enzymatic] model for a gene therapy against HIV". Makerere Med J. 38: 28–30.
Lonza Group (1,759 words) [view diff] exact match in snippet view article find links to article
of Houston). This is one of four sites which are focused on cell and gene therapy, the other three being in Portsmouth, New Hampshire; Geleen, Netherlands;
Epilepsy-intellectual disability in females (4,199 words) [view diff] no match in snippet view article find links to article
Epilepsy-intellectual disability in females also known as PCDH19 gene-related epilepsy or epileptic encephalopathy, early infantile, 9 (EIEE9), is a rare
Netherlands Institute for Neuroscience (726 words) [view diff] exact match in snippet view article find links to article
Start2Cure Foundation for a project to investigate the potential of a gene therapy approach to treat multiple sclerosis and to identify the genes involved
José-Alain Sahel (2,067 words) [view diff] exact match in snippet view article find links to article
biology, functional genomics, physiology and therapeutics (stem cells, gene therapy, pharmacology, artificial retina), research on relevant biomarkers and
Rose (Marvel Comics) (820 words) [view diff] no match in snippet view article
Phillip Hayes. He took up the Rose persona after he lost his funding in gene-therapy research after an accident in the Phelcorps laboratory, a result of which
Herpes simplex research (8,110 words) [view diff] exact match in snippet view article find links to article
by a cytotoxic approach examined a way to eradicate malignant tumors. Gene therapy is based on the cytotoxic genes that directly or indirectly kill tumor
John Ryker (646 words) [view diff] exact match in snippet view article find links to article
Corporation, which specializes in giving average people superpowers through gene therapy, and sending the new Gamma Corps: Black unit under Norman Osborn's auspices
José-Alain Sahel (2,067 words) [view diff] exact match in snippet view article find links to article
biology, functional genomics, physiology and therapeutics (stem cells, gene therapy, pharmacology, artificial retina), research on relevant biomarkers and
Maternal–fetal medicine (1,274 words) [view diff] case mismatch in snippet view article find links to article
Abi-Nader, Khalil N.; Rodeck, Charles H.; David, Anna L. (2009). "Prenatal Gene Therapy for the Early Treatment of Genetic Disorders". Expert Review of Obstetrics
Infected cell protein 34.5 (262 words) [view diff] case mismatch in snippet view article find links to article
with enhanced oncolytic, immune stimulating, and anti-tumour properties". Gene Therapy. 10 (4): 292–303. doi:10.1038/sj.gt.3301885. PMID 12595888. v t e
Provirus silencing (270 words) [view diff] exact match in snippet view article find links to article
This often leads to harmful impact on the host. However, in recent gene therapy techniques, retroviruses are often used to deliver desired genes instead
H19 (gene) (6,235 words) [view diff] exact match in snippet view article
of using the H19 promoter in gene therapy to drive the expression of cytotoxic genes in tumorigenic cells. Gene therapy trials utilizing the H19 promoter
Roscoe Brady (1,158 words) [view diff] exact match in snippet view article find links to article
investigating substrate depletion, molecular chaperone therapy, and gene therapy for patients with metabolic storage disorders. Among his numerous awards
European Society for Primary Immunodeficiencies (657 words) [view diff] exact match in snippet view article find links to article
Bone Marrow Transplantation and Gene Therapy Working Party works to "improve the outcome of transplant and gene therapy for severe congenital immunodeficiencies
Timothy O'Brien (endocrinologist) (284 words) [view diff] exact match in snippet view article
regenerative medicine, an emerging field that combines the technologies of gene therapy and adult stem cell therapy. The goal is to use cells and genes to regenerate
Off-target genome editing (6,818 words) [view diff] exact match in snippet view article find links to article
off-target modification needs to be rendered obsolete. The safety of gene therapy treatment is of utmost concern, especially during clinical trials when
Poly(amidoamine) (4,500 words) [view diff] exact match in snippet view article
broad range of cell lines, they have taken an important place in modern gene therapy methodologies. The biotechnology company Qiagen currently offers two
Lee Rayfield (501 words) [view diff] case mismatch in snippet view article find links to article
Society of Ordained Scientists (SOSc) since 1995, and served on the Gene Therapy Advisory Committee (2000–2009) and on the Human Fertilisation and Embryology
David Baskin (795 words) [view diff] exact match in snippet view article find links to article
the Journal of Clinical Oncology regarding the efficacy of a type of gene therapy for malignant glioma, the most common form of brain tumor. This trial
Panos Ioannou (425 words) [view diff] case mismatch in snippet view article find links to article
Research Institute, Melbourne, Australia, where he led the Cell and Gene Therapy (CAGT) Research Group. He concentrated on the development of novel therapies
FUT8 (996 words) [view diff] case mismatch in snippet view article find links to article
(PDF). BioDrugs : Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy. 31 (3): 151–166. doi:10.1007/s40259-017-0223-8. PMID 28466278. S2CID 3722081
Hunter syndrome (2,581 words) [view diff] exact match in snippet view article find links to article
II was treated with gene therapy in an attempt to prevent further damage by the disease. This is the first case of gene therapy being used in vivo in
Retinitis (624 words) [view diff] exact match in snippet view article find links to article
One study including patients with retinitis was conducted by using gene therapy. Goldman, Lee (2011). Goldman-Cecil Medicine (24th ed.). Philadelphia:
AAV (169 words) [view diff] exact match in snippet view article find links to article
(2005-2008) Adeno-associated virus, a nonpathogenic virus used as a gene therapy tool Air admittance valve, a valve in a drain-waste-vent system Another
Colloidal gold (9,422 words) [view diff] no match in snippet view article find links to article
Colloidal gold is a sol or colloidal suspension of nanoparticles of gold in a fluid, usually water. The colloid is usually either an intense red colour
Kyowa Hakko Kirin (394 words) [view diff] case mismatch in snippet view article find links to article
(PDF). BioDrugs : Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy. 31 (3): 151–166. doi:10.1007/s40259-017-0223-8. PMID 28466278. S2CID 3722081
Isabelle M. Germano (1,607 words) [view diff] exact match in snippet view article find links to article
focus on brain tumors translational research with particular emphasis on gene therapy, stem cells, and induced pluripotent stem cells (iPSC).[citation needed]
Laura Brod (703 words) [view diff] exact match in snippet view article find links to article
effective gene therapy treatments for children with ultra rare genetic diseases. CCF was one of the first nonprofit biotechs in the gene therapy space with
Cell encapsulation (8,763 words) [view diff] exact match in snippet view article find links to article
primarily as anti-cancer treatments, but also exploring possible uses for gene therapy or antibody therapies. Using cellulose sulphate it has been possible
UCLA School of Nursing (1,612 words) [view diff] exact match in snippet view article find links to article
wound care Cellular targets for Alzheimer's treatments or prevention Gene therapy that has high potential to advance the science in HIV/AIDS Nutritional
Titer (667 words) [view diff] exact match in snippet view article find links to article
Michael G. Kaplitt; Arthur D. Loewy (August 1, 1995). Viral vectors: gene therapy and neuroscience applications. Academic Press. p. 304. ISBN 978-0-12-397570-6
Naoto Ueno (326 words) [view diff] exact match in snippet view article find links to article
breast cancer. He is best known for his preclinical development of E1A gene therapy and multiple preclinical development which led to novel clinical trials
Polypurine reverse-Hoogsteen hairpin (1,402 words) [view diff] exact match in snippet view article find links to article
stress (WEE1, CHK1) and Thymidilate synthase (TYMS) as part of a cancer gene therapy strategy. Their preclinical proof of principle has been proven in vivo
CDKL5 deficiency disorder (2,127 words) [view diff] exact match in snippet view article find links to article
clinical trial in CDD with fenfluramine Gene therapy Amicus announced a collaboration around a new AAV (gene therapy)-based technology to complement their
ALS Therapy Development Institute (1,271 words) [view diff] exact match in snippet view article find links to article
Foundation's first therapy concept was to replace EAAT2 protein using gene therapy. In 2004, the Foundation moved to a 16,000-square-foot (1,500 m2) location
Rudolf Podgornik (1,184 words) [view diff] exact match in snippet view article find links to article
Nonviral Vectors for Gene Delivery", in the leading textbook of gene therapy: "Gene Therapy: Therapeutic Mechanisms and Strategies" [5], N. Smyth – Templeton
CDV3 (gene) (919 words) [view diff] exact match in snippet view article
hepatocellular carcinoma. CDV3 has been considered as a potential target for gene therapy. It encodes the protein Histone H4. Related gene families include plasma
ALS Therapy Development Institute (1,271 words) [view diff] exact match in snippet view article find links to article
Foundation's first therapy concept was to replace EAAT2 protein using gene therapy. In 2004, the Foundation moved to a 16,000-square-foot (1,500 m2) location
Allan M. Campbell (1,129 words) [view diff] exact match in snippet view article find links to article
profound influence on several fields, including molecular cloning and gene therapy." Campbell's research has concentrated on the genetics of bacteria and
Impalefection (337 words) [view diff] case mismatch in snippet view article find links to article
1089/152489000414552. Huang, Leaf; Liu, Dexi (2015). Nonviral Vectors for Gene Therapy: Physical Methods and Medical Translation. Academic Press. p. 7. Pearce
Ernst Freese (714 words) [view diff] exact match in snippet view article find links to article
organized the first comprehensive conference focused on the prospects of gene therapy through the John E. Fogarty International Center. His laboratory identified
Scientific American (3,852 words) [view diff] case mismatch in snippet view article find links to article
of Higgs The End of the Space Shuttle Program The Death of Steve Jobs Gene Therapy Makes a Comeback The Sun Sets on Solyndra IBM's Watson Computer Wins
Timothy Ray Brown (1,177 words) [view diff] case mismatch in snippet view article find links to article
Retrieved March 31, 2009. Lunzen, J.; Fehse, B.; Hauber, J. (2011). "Gene Therapy Strategies: Can We Eradicate HIV?". Current HIV/AIDS Reports. 8 (2):
Tulane University School of Medicine (2,520 words) [view diff] case mismatch in snippet view article find links to article
and master of public health degrees. In 2001, the Tulane Center for Gene Therapy started as the first major center in the U.S. to focus on research using
N-Acetylglutamate synthase deficiency (438 words) [view diff] exact match in snippet view article find links to article
amino acid mixture and arginine, citrulline, experimental attempts at gene therapy, liver transplantation (which is curative), and also N-carbamylglutamate
Mary Ann Liebert (453 words) [view diff] case mismatch in snippet view article find links to article
Journal of Women's Health and Gender-Based Medicine (5,000), Human Gene Therapy (2,300), and AIDS Research and Human Retrovirus (2,150). In February
Adenovirus vaccine (526 words) [view diff] exact match in snippet view article find links to article
induced innate immune responses: impact upon efficacy and toxicity in gene therapy and vaccine applications". Virus Res. 132 (1–2): 1–14. doi:10.1016/j
Rev (HIV) (2,852 words) [view diff] exact match in snippet view article
replication in cell lines and primary T cells: implication for gene therapy of AIDS". Gene Therapy. 4 (2): 128–39. doi:10.1038/sj.gt.3300369. PMID 9081703.
Shimon Slavin (4,143 words) [view diff] exact match in snippet view article find links to article
San Raffaele Hospital in Milan pioneered the first successful use of gene therapy for treatment of bubble baby born with adenosine deaminase deficiency
Raymond F. Schinazi (2,433 words) [view diff] exact match in snippet view article find links to article
pharmacological and molecular genetic approaches, including molecular modeling and gene therapy. Schinazi was born on March 21, 1950 in Alexandria, Egypt to Jewish parents
Stargardt disease (2,380 words) [view diff] exact match in snippet view article find links to article
trials in various stages involving several potential therapeutic areas, gene therapy, stem cell therapy, drug therapy and artificial retinas. In general all
Martin Cline (242 words) [view diff] exact match in snippet view article find links to article
disorders. He did so in direct opposition to National Institute of Health gene therapy guidelines and without the approval of the Institutional Review Board
Green fluorescent protein (7,284 words) [view diff] exact match in snippet view article find links to article
been found that new lines of transgenic GFP rats can be relevant for gene therapy as well as regenerative medicine. By using "high-expresser" GFP, transgenic
Tripeptidyl peptidase I (1,559 words) [view diff] exact match in snippet view article find links to article
function deficits and structural changes. This result implies that ex vivo gene therapy using autologous stem cells may be an effective means of achieving sustained
H. Michael Shepard (721 words) [view diff] exact match in snippet view article find links to article
since it became available. Shepard has made seminal contributions to gene therapy of cancer, to tumor suppressor gene targeted small molecule therapeutics
RNA hydrolysis (726 words) [view diff] exact match in snippet view article find links to article
out in a controlled way. Applications include the use of ribozymes in gene therapy to control gene expression in bacteria and eukaryotes, and to inhibit
Transthyretin (2,349 words) [view diff] exact match in snippet view article find links to article
has historically relied on liver transplantation as a crude form of gene therapy. Because TTR is primarily produced in the liver, replacement of a liver
Adoptive cell transfer (4,004 words) [view diff] exact match in snippet view article find links to article
Ragnarsson GB, Greenberg PD (November 2009). "T cell receptor gene therapy for cancer". Human Gene Therapy. 20 (11): 1240–8. doi:10.1089/hum.2009.146. PMC 2829456
Management of HIV/AIDS (15,725 words) [view diff] exact match in snippet view article find links to article
research into other methods to try to block CCR5 expression through gene therapy. A procedure zinc-finger nuclease-based gene knockout has been used in
Bioassay (1,237 words) [view diff] case mismatch in snippet view article find links to article
PMID 14449182. "Guidance for Industry: Potency Tests for Cellular and Gene Therapy Products". Washington, D.C.: U.S. Food and Drug Administration. January
Gap junction (8,042 words) [view diff] exact match in snippet view article find links to article
retroviral gene therapy". Hum. Gene Ther. 4 (6): 725–31. doi:10.1089/hum.1993.4.6-725. PMID 8186287. Pitts, JD (November 1994). "Cancer gene therapy: a bystander
How Many (182 words) [view diff] case mismatch in snippet view article find links to article
Disc 2 "How Many" (Vibelicious Radio Edit) "How Many" (DJ Manolo and Gene Therapy Mix) "How Many" (Big Bang Mix) "How Many" (Bet Boyz Vocal Dub) "How Many"