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Thymidine kinase
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poxviruses. The herpesvirus thymidine kinase gene has also been used as a "suicide gene" as a safety system in gene therapy experiments, allowing cells expressingVirotherapy (3,501 words) [view diff] exact match in snippet view article find links to article
types of treatment methods: gene overexpression, gene knockout, and suicide gene delivery. Gene overexpression adds genetic sequences that compensateHorne Prize (554 words) [view diff] case mismatch in snippet view article find links to article
journalism in Australia. The inaugural winner was Anna Spargo-Ryan for The Suicide Gene. In 2018 a guideline was introduced concerning the need for people fromTK cell therapy (487 words) [view diff] exact match in snippet view article find links to article
the genetical engineering of donor T lymphocytes in order to express a suicide gene (thymidine kinase of the Herpes simplex virus, namely TK) Once the lymphocytesOncolytic virus (8,503 words) [view diff] exact match in snippet view article find links to article
neighbouring cells. One herpes simplex virus, encoding a thymidine kinase suicide gene, has progressed to phase III clinical trials. The herpes simplex virusBruce Lahn (1,137 words) [view diff] exact match in snippet view article find links to article
is currently working on. They range anywhere from looking at if the suicide gene can be modified with stem cells, to looking at stem cells as a potentialCAR T cell (8,019 words) [view diff] exact match in snippet view article find links to article
that have been integrated into CAR T cells. In the iCasp9 system, the suicide gene complex has two elements: a mutated FK506-binding protein with high specificityAnna Spargo-Ryan (877 words) [view diff] case mismatch in snippet view article find links to article
2016 she was the inaugural winner of the Horne Prize for her essay The Suicide Gene. Anna Spargo-Ryan was born in Adelaide, South Australia, and educatedGenetics of aging (2,249 words) [view diff] exact match in snippet view article find links to article
senescent cells from progeroid mice by introducing a drug-inducible suicide gene and then treating the mice with the drug to kill senescent cells selectivelyHuman artificial chromosome (1,264 words) [view diff] exact match in snippet view article find links to article
herpes simplex virus thymidine kinase coding gene into tumor cells. This "suicide gene" is required to activate many antiviral medications. These targeted tumorCytosine deaminase (221 words) [view diff] case mismatch in snippet view article find links to article
(2015-08-11). "Bioactive Core–Shell Nanofiber Hybrid Scaffold for Efficient Suicide Gene Transfection and Subsequent Time Resolved Delivery of Prodrug for AnticancerThe Human Condition (Man Must Die album) (117 words) [view diff] case mismatch in snippet view article
"You Stand Alone" – 4:29 "Elitist" – 4:39 "Organized Insanity" – 3:19 "Suicide Gene" – 5:34 Joe McGlynn – vocals Alan McFarland – guitar Danny McNab – bassSave the Green Planet! (1,306 words) [view diff] exact match in snippet view article find links to article
Odyssey), about how his race was originally trying to save humanity from a suicide gene (that leads to killing a member of their own species) by experimentingDavid Baskin (720 words) [view diff] exact match in snippet view article find links to article
3611–3619. doi:10.1200/JCO.2011.35.5222. PMC 3179270. PMID 21844505. "Novel suicide gene therapy combined with standard treatment treats malignant brain tumors"Herpes simplex research (8,434 words) [view diff] exact match in snippet view article find links to article
assist in the treatment of malignant tumors. A study conducted using suicide gene transfer by a cytotoxic approach examined a way to eradicate malignantDeaths in December 2001 (4,909 words) [view diff] no match in snippet view article find links to article
Mayol, 74, French diver and holder of many records in free diving, suicide. Gene Taylor, 72, American jazz double bassist. Liu Zihou, 92, Chinese politicianCombinatorial ablation and immunotherapy (1,148 words) [view diff] exact match in snippet view article find links to article
S (2000). "Eradication of breast cancer xenografts by hyperthermic suicide gene therapy under the control of the heat shock protein promoter". HumanBrain tumor (10,618 words) [view diff] exact match in snippet view article find links to article
Wang WJ, Chen TC, Kasahara N (November 2005). "Single-shot, multicycle suicide gene therapy by replication-competent retrovirus vectors achieves long-termTelomerase reverse transcriptase (5,301 words) [view diff] exact match in snippet view article find links to article
Lee KW, Kim MH, Kim KT, et al. (November 2003). "Adenovirus-mediated suicide gene therapy using the human telomerase catalytic subunit (hTERT) gene promoterChelsea Watego (1,736 words) [view diff] case mismatch in snippet view article find links to article
nominated for the 2016 Horne Prize, but lost to Anna Spargo-Ryan's The Suicide Gene. From 2017 to 2020, she hosted Wild Black Women with Angelina HurleyCaspase-9 (4,330 words) [view diff] exact match in snippet view article find links to article
binding protein. iCasp9 can be added to the CAR T cells as an inducible suicide gene. If therapy with CAR T cells results in severe side effects, iCasp9 can5-HT2A receptor (9,591 words) [view diff] no match in snippet view article find links to article
serotonin 2A receptor genetic variations, stressful life events and suicide". Gene. 658: 191–197. doi:10.1016/j.gene.2018.03.023. PMID 29526601. S2CID 4854262Management of HIV/AIDS (15,824 words) [view diff] exact match in snippet view article find links to article
PMID 24597865. HIV-1 CCR5 gene therapy will fail unless it is combined with a suicide gene Aridaman Pandit & Rob J. de Boer. Scientific Reports volume 5, ArticleOncolytic adenovirus (4,209 words) [view diff] exact match in snippet view article find links to article
"Phase I study of replication-competent adenovirus-mediated double suicide gene therapy for the treatment of locally recurrent prostate cancer". CancerSynthetic biology (18,297 words) [view diff] exact match in snippet view article find links to article
F. & Di Stasi, A. Improving the safety of cell therapy products by suicide gene transfer. Front. Pharmacol. 5, 254 (2014). Wei P, Wong WW, Park JS, CorcoranArtificial gene synthesis (7,073 words) [view diff] exact match in snippet view article find links to article
cassette flanked by attP sites. The Gateway cassette contains a bacterial suicide gene (e.g. ccdB) that will allow for survival and selection of successfullyList of deaths from drug overdose and intoxication (17,712 words) [view diff] case mismatch in snippet view article find links to article
their arms Ruan Lingyu 1910 1935 24 Actress Sleeping pills Disputed suicide Gene Lipscomb 1931 1963 31 American football player Heroin Unknown AthinaList of deaths in rock and roll (1980s) (855 words) [view diff] case mismatch in snippet view article
John Spence No Doubt 18 December 21, 1987 Anaheim, California, U.S. Suicide Gene "Bowlegs" Miller 54 December 25, 1987 Memphis, Tennessee, U.S. UnknownRachel Kann (3,212 words) [view diff] exact match in snippet view article find links to article
deficit hyperactivity disorder in her art, describing herself as having a "suicide gene" and suggesting that "ADD-doused hyperactivity" caused her childhood