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searching for FOXP3 64 found (128 total)

alternate case: fOXP3

Neurovax (139 words) [view diff] exact match in snippet view article find links to article

currently in phase II clinical trials. Neurovax is designed to stimulate FOXP3+ regulatory T-cells that can then suppress the autoreactive T-cells in some
Hassall's corpuscles (542 words) [view diff] case mismatch in snippet view article find links to article
increases the ability of dendritic cells to convert naive thymocytes to a Foxp3+ regulatory T cell lineage. It is unknown if this is the physiological function
Death receptor 3 (1,586 words) [view diff] case mismatch in snippet view article find links to article
antigen-experienced T lymphocytes. TNFRSF25 is also highly expressed by FoxP3 positive regulatory T lymphocytes. TNFRSF25 is activated by a monogamous
IL2RA (558 words) [view diff] case mismatch in snippet view article find links to article
oligodendrocytes. Though IL2RA has been used as a marker to identify CD4+FoxP3+ regulatory T cells in mice, it has been found that a large proportion of
Hydroxycarboxylic acid receptor 2 (2,029 words) [view diff] exact match in snippet view article find links to article
causing increased acetylation of histone H3 in the Foxp3 CNS1 region, and thereby enhancing FOXP3 expression (180, 181). Short-chain fatty acids partially
Autoimmune enteropathy (453 words) [view diff] exact match in snippet view article find links to article
FOXP3 gene. This can only affect boys. Type 2: IPEX-like, which manifests similarly to IPEX syndrome but without recognizable mutations in the FOXP3 gene
GPR83 (325 words) [view diff] case mismatch in snippet view article find links to article
83 overexpression in naive CD4+CD25- T cells leads to the induction of Foxp3+ regulatory T cells in vivo". J. Immunol. 177 (1): 209–15. doi:10.4049/jimmunol
Hashimoto's thyroiditis (5,516 words) [view diff] case mismatch in snippet view article find links to article
secretion of TGF-β (inhibitor of cytokine production), and mutations of FoxP3, an essential regulatory factor for the Tregs development. Development of
Alfred Singer (920 words) [view diff] case mismatch in snippet view article find links to article
Wiessman JD, Singer A, Singer DS: Regulation of MHC class I expression by Foxp3 and its effect on regulatory T cell function. Journal of Immunology. 192:
Thymic epithelial cell (1,358 words) [view diff] case mismatch in snippet view article find links to article
implementation of self tolerance, which is mediated by CD4+CD25+Foxp3 nTreg cells. Foxp3 Treg development is supported by mTECs during negative selection
Decitabine (667 words) [view diff] exact match in snippet view article find links to article
Moon C, Kim SH (June 2009). "Use of epigenetic modification to induce FOXP3 expression in naïve T cells". Transplant. Proc. 41 (5): 1848–1854. doi:10
Decitabine (667 words) [view diff] exact match in snippet view article find links to article
Moon C, Kim SH (June 2009). "Use of epigenetic modification to induce FOXP3 expression in naïve T cells". Transplant. Proc. 41 (5): 1848–1854. doi:10
Mohan R. Wani (802 words) [view diff] case mismatch in snippet view article find links to article
Attenuates Collagen-Induced Arthritis by Modulating the Development of Foxp3+ Regulatory T Cells". The Journal of Immunology. 186 (4): 2262–2272. doi:10
Theralizumab (4,126 words) [view diff] exact match in snippet view article find links to article
FOXP3. However, eventually most of these cells downregulate their regulatory capabilities and become effector cells. Thus, attempts to induce FOXP3+
Trichostatin A (513 words) [view diff] exact match in snippet view article find links to article
(SAHA) Moon C, Kim SH (June 2009). "Use of epigenetic modification to induce FOXP3 expression in naïve T cells". Transplant. Proc. 41 (5): 1848–54. doi:10
Shyam Sundar (academic) (441 words) [view diff] case mismatch in snippet view article
Splenic accumulation of IL-10 mRNA in T cells distinct from CD4+CD25+ (Foxp3) regulatory T cells in human visceral leishmaniasis Trial of oral miltefosine
Harald von Boehmer (1,423 words) [view diff] case mismatch in snippet view article find links to article
MacIsaac, K. D., Levine, S. S., Fraenkel, E., von Boehmer, H., Young, R. A.: Foxp3 occupancy and regulation of key target genes during T-cell stimulation.
Thymic stromal lymphopoietin (1,574 words) [view diff] exact match in snippet view article find links to article
lymphopoietin-activated plasmacytoid dendritic cells induce the generation of FOXP3+ regulatory T cells in human thymus". Journal of Immunology. 184 (6): 2999–3007
MiR-155 (10,332 words) [view diff] case mismatch in snippet view article find links to article
Scudamore C, Turner M, Okkenhaug K, Vigorito E (Mar 2009). "Cutting edge: the Foxp3 target miR-155 contributes to the development of regulatory T cells". Journal
Lung microbiota (1,671 words) [view diff] exact match in snippet view article find links to article
response and anti-inflammatory interleukin (IL)-10, antimicrobial peptides, FOXP3, secretory immunoglobulin A (sIgA) production. Changes in microbial community
Leukocyte apheresis (293 words) [view diff] case mismatch in snippet view article find links to article
PMC 1727082. PMID 9616306. Muratov V.; et al. (2008). "Decreased numbers of FoxP3-positive and TLR-2-positive cells in intestinal mucosa are associated with
Interleukin 29 (1,659 words) [view diff] exact match in snippet view article find links to article
"Interferon-lambda-treated dendritic cells specifically induce proliferation of FOXP3-expressing suppressor T cells". Blood. 107 (11): 4417–23. doi:10.1182/blood-2005-10-4129
Interleukin-7 receptor-α (824 words) [view diff] exact match in snippet view article find links to article
"Cell-surface IL-7 receptor expression facilitates the purification of FOXP3(+) regulatory T cells". Trends Immunol. 27 (12): 541–4. doi:10.1016/j.it
Interferon Lambda 3 (1,468 words) [view diff] exact match in snippet view article find links to article
"Interferon-lambda-treated dendritic cells specifically induce proliferation of FOXP3-expressing suppressor T cells". Blood. 107 (11): 4417–23. doi:10.1182/blood-2005-10-4129
Brigitta Stockinger (740 words) [view diff] case mismatch in snippet view article find links to article
; O'Garra, A (2004). "IL-10-secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occurring CD4+CD25+
Javier Arias Stella (891 words) [view diff] exact match in snippet view article find links to article
suppressive B7H4(+) macrophages and the subpopulation of CD25(+) CD4(+) and FOXP3(+) regulatory T-cells in decidua during the secretory cycle phase, Arias
Interleukin 7 (1,666 words) [view diff] case mismatch in snippet view article find links to article
CD4+ T cells with a commensurate decrease in the percentage of CD4+CD25+Foxp3+ T regulatory cells. No objective cancer regression was observed, however
Immunosuppressive drug (2,984 words) [view diff] exact match in snippet view article find links to article
Mofetil-Based Immunosuppression Changes the Frequency and Phenotype of CD4+FOXP3+ Regulatory T Cells". Transplantation. 87 (7): 1062–1068. doi:10.1097/tp
MARCH7 (525 words) [view diff] exact match in snippet view article find links to article
Y, et al. (2007). "Evidence for functional inter-relationships between FOXP3, leukaemia inhibitory factor, and axotrophin/MARCH-7 in transplantation
Urbanization (9,428 words) [view diff] case mismatch in snippet view article find links to article
of developing asthma. Studies have shown a positive correlation between Foxp3 methylation and children's exposure to NO2, CO, and PM2.5. Furthermore,
Sertoli cell (2,862 words) [view diff] case mismatch in snippet view article find links to article
decreasing proliferation of effector T-cells Jagged1 (JAG1) – induction of Foxp3 transcription factor expression in naive T lymphocytes (increasing relative
Co-receptor (3,129 words) [view diff] case mismatch in snippet view article find links to article
effect then spreads to native T cells which then switch to a CD4+CD25+GITR+FoxP3+ T regulatory phenotype. Currently, the two most prominent areas of co-receptor
Chemoimmunotherapy (988 words) [view diff] exact match in snippet view article find links to article
growth and inhibit tumor-associated immune responses, including CD4+CD25+FOXP3+ regulatory T cells (Tregs), CD4+interleukin-17-producing T helper cells
Microchimerism (5,060 words) [view diff] exact match in snippet view article find links to article
interface. Mother’s fetal-specific CD4+ T cells proliferate, and due to FOXP3 expression, differentiate into Treg cells. Mice models show that fetal-specific
NFKBID (838 words) [view diff] case mismatch in snippet view article find links to article
"IκB(NS) protein mediates regulatory T cell development via induction of the Foxp3 transcription factor". Immunity. 37 (6): 998–1008. doi:10.1016/j.immuni
Acrolein (1,931 words) [view diff] case mismatch in snippet view article find links to article
prevents allergy but accelerates tumor growth by promoting immunoregulatory Foxp3+ cells: Mouse model for passive respiratory exposure". Scientific Reports
CD86 (3,195 words) [view diff] case mismatch in snippet view article find links to article
PMID 31130955. Onishi Y, Fehervari Z, Yamaguchi T, Sakaguchi S (July 2008). "Foxp3+ natural regulatory T cells preferentially form aggregates on dendritic
Aplastic anemia (4,319 words) [view diff] exact match in snippet view article find links to article
expression of HLA‐DR2 and HLA‐DR15 (mean age of two groups- 34 and 21 years), FOXP3, CD95, and CCR4, lower expression of CD45RA (mean age – 45 years), and expression
Regulatory macrophages (1,834 words) [view diff] case mismatch in snippet view article find links to article
Evans HG, van Herwijnen MJ, John S, Taams LS (December 2007). "CD4+CD25+Foxp3+ regulatory T cells induce alternative activation of human monocytes/macrophages"
Immune privilege (3,157 words) [view diff] case mismatch in snippet view article find links to article
(IL-10) have all been implicated in the induction of immune tolerance. Foxp3 and neuropillin are markers expressed by the regulatory T-cells by which
Autoimmunity (5,475 words) [view diff] case mismatch in snippet view article find links to article
Regulatory T cell theory, wherein regulatory T-lymphocytes (commonly CD4+FoxP3+ cells, among others) function to prevent, downregulate, or limit autoaggressive
FCRL3 (1,837 words) [view diff] exact match in snippet view article find links to article
natural killer cells, CD4+ and CD8+ T cells, as well as regulatory CD4+FOXP3+ T cells. Notably, it has also been observed on a subpopulation of natural
Vitamin A (6,491 words) [view diff] case mismatch in snippet view article find links to article
intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid". The Journal of Experimental Medicine. 204
Prostaglandin DP1 receptor (3,020 words) [view diff] case mismatch in snippet view article find links to article
cells to suppress airway allergic inflammation by increasing the number of Foxp3+ CD4+ ][regulatory T cell]s]. Furthermore, DP1 activation reduces eosinophilia
List of autoimmune diseases (3,385 words) [view diff] exact match in snippet view article find links to article
J. J.; Nieuwenhuis, Edward E. (2007). "IPEX as a Result of Mutations in FOXP3". Clinical and Developmental Immunology. 2007: 89017. doi:10.1155/2007/89017
John J. O'Shea (1,263 words) [view diff] case mismatch in snippet view article find links to article
Davidson, T. S.; Ramsey, H.; O'Shea, J. J.; Shevach, E. M. (2008). "CD4+FoxP3+ regulatory T cells confer infectious tolerance in a TGF- -dependent manner"
Kari Nadeau (2,614 words) [view diff] case mismatch in snippet view article find links to article
immunotherapy) on Treg function and epigenetic changes of pivotal loci in Foxp3 and IL-10, IFN-γ, and IL-4. This research led to novel findings on markers
Juven (1,205 words) [view diff] exact match in snippet view article find links to article
Schulze JJ, Olek S, Kühn T (September 2016). "The Ratio of Regulatory (FOXP3+) to Total (CD3+) T Cells Determined by Epigenetic Cell Counting and Cardiovascular
Bernd Schröppel (1,055 words) [view diff] case mismatch in snippet view article find links to article
signals have physiologically divergent effects on epigenetic regulation of Foxp3 expression and Treg function, Am J Transplantation, 11(2):203-214, 2011
LAG3 (6,239 words) [view diff] case mismatch in snippet view article find links to article
Castelli C (Jun 2010). "LAG-3 expression defines a subset of CD4(+)CD25(high)Foxp3(+) regulatory T cells that are expanded at tumor sites". Journal of Immunology
Siddhartha Mukherjee (4,484 words) [view diff] case mismatch in snippet view article find links to article
decarboxylase (HDC)-expressing granulocytic myeloid cells induce and recruit Foxp3+ regulatory T cells in murine colon cancer". OncoImmunology. 6 (3): e1290034
Spirocerca lupi (2,095 words) [view diff] case mismatch in snippet view article find links to article
organized lymphoid foci. There was no evidence of local accumulation of FoxP3+ cells, unlike many previous studies that reported elevated numbers of this
T cell receptor revision (1,333 words) [view diff] case mismatch in snippet view article find links to article
Pamela J. (Nov 1, 2007). "Cutting edge: TCR revision affects predominantly Foxp3 cells and skews them toward the Th17 lineage". Journal of Immunology. 179
Short course immune induction therapy (2,444 words) [view diff] case mismatch in snippet view article find links to article
induction and transient depletion of T cells, but an increase in CD4+ and CD8+ Foxp3+Tregs. While promising, islet function gradually decreased over time in
Mario Rosemblatt (1,366 words) [view diff] case mismatch in snippet view article find links to article
Fierro. Dendritic Cells and B Cells Cooperate in the Generation of CD4+CD25+Foxp3+ Allogeneic T Cells. Transplant. Proc. 42; 371-5, 2010 Elgueta R., Sepulveda
Microbial symbiosis and immunity (4,499 words) [view diff] exact match in snippet view article find links to article
and can also neutralize PAMPs. IgA promotes the development of TH17 and FOXP3+ regulatory T cells. Given its critical function in the GI tract, the number
Martin Turner (scientist) (1,629 words) [view diff] case mismatch in snippet view article
C., Turner, M., Okkenhaug, K., Vigorito, E. (2009). Cutting edge: The Foxp3 target miR-155 contributes to the development of regulatory T cells. J.
CD4+ T cells and antitumor immunity (3,981 words) [view diff] case mismatch in snippet view article find links to article
and immune homeostasis. Treg differentiation is induced by expression of FoxP3 transcription factor, and Tregs secrete a variety of immunosuppressive cytokines
Sankar Ghosh (2,344 words) [view diff] case mismatch in snippet view article find links to article
modulates regulatory T cell development by directly regulating expression of Foxp3 transcription factor. Immunity 18: 921-931. Park, S.-G., Schulze-Luehrman
Medullary thymic epithelial cells (3,472 words) [view diff] case mismatch in snippet view article find links to article
Hinterberger M, Emmerich J, Swee LK, Rolink A, Klein L (April 2007). "Selection of Foxp3+ regulatory T cells specific for self antigen expressed and presented by
C20orf27 (3,042 words) [view diff] exact match in snippet view article find links to article
Y, Li R, Guo TB, He D, Fang L, et al. (March 2013). "Phosphorylation of FOXP3 controls regulatory T cell function and is inhibited by TNF-α in rheumatoid
Francisco J. Quintana (1,816 words) [view diff] case mismatch in snippet view article find links to article
Quintana FJ. Aryl hydrocarbon receptor activation induces human Tr1-like and Foxp3+ Treg cells. Nature Immunology 11, 846-53 (2010). 6. Yeste, A., Nadeau,
Metronomic therapy (2,949 words) [view diff] exact match in snippet view article find links to article
means to evade immunosurveillance of the host. The number of CD4+ CD25+ FOXP3+ regulatory T cells (Tregs) was found to increase in various types of tumors
List of human transcription factors (81 words) [view diff] exact match in snippet view article find links to article
ENSG00000128573 Forkhead Known motif – High-throughput in vitro [281] RTAAAYAW FOXP3 ENSG00000049768 Forkhead Known motif – High-throughput in vitro [282] RTAAACA