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searching for Co-receptor 129 found (244 total)

alternate case: co-receptor

Innate resistance to HIV (1,725 words) [view diff] exact match in snippet view article find links to article

main mechanism is a mutation of the gene encoding CCR5, which acts as a co-receptor for HIV. It is estimated that the proportion of people with some form
LRP6 (1,403 words) [view diff] exact match in snippet view article find links to article
by the LRP6 gene. LRP6 is a key component of the LRP5/LRP6/Frizzled co-receptor group that is involved in canonical Wnt pathway. LRP6 is a transmembrane
LRP5 (3,189 words) [view diff] exact match in snippet view article find links to article
by the LRP5 gene. LRP5 is a key component of the LRP5/LRP6/Frizzled co-receptor group that is involved in canonical Wnt pathway. Mutations in LRP5 can
Interleukin 11 (2,522 words) [view diff] exact match in snippet view article find links to article
IL-6-type cytokine family, distinguished based on their use of the common co-receptor gp130. Signal specificity is provided by the IL-11Rα subunit which is
HIV tropism (616 words) [view diff] exact match in snippet view article find links to article
patient is infected with virus that enters cells using the R5 co-receptor, the X4 co-receptor, or both (dual/mixed). Patients with strains of HIV that prefer
Neuregulin 3 (2,559 words) [view diff] exact match in snippet view article find links to article
heterodimers, often consisting of ERBB2, which is thought to function as a co-receptor as it has not been observed to bind any ligand. NRGs bind to the ERBB
CD8A (1,282 words) [view diff] exact match in snippet view article find links to article
CO-RECEPTOR CD8 AT 2.6 ANGSTROMS RESOLUTION 2hp4: Computational design and crystal structure of an enhanced affinity mutant human CD8-alpha-alpha co-receptor
Jasmonate (2,887 words) [view diff] exact match in snippet view article find links to article
demonstrating InsP5 to be a necessary component of the co-receptor and playing a role in potentiating the co-receptor complex. Sheard's results may show varying binding
Maraviroc (954 words) [view diff] exact match in snippet view article find links to article
of certain human cells. The chemokine receptor CCR5 is an essential co-receptor for most HIV strains and necessary for the entry process of the virus
Repulsive guidance molecule B (603 words) [view diff] exact match in snippet view article find links to article
guidance and outgrowth of neurite), is a bone morphogenetic protein (BMP) co-receptor of the repulsive guidance molecule family. In humans this protein is
MHC restriction (2,243 words) [view diff] exact match in snippet view article find links to article
such that both germline-encoded interactions between TCR and MHC and co-receptor interactions with CD4 or CD8 to signal T cell maturation occur during
GFRA1 (1,489 words) [view diff] exact match in snippet view article find links to article
"Over-representation of a germline variant in the gene encoding RET co-receptor GFRalpha-1 but not GFRalpha-2 or GFRalpha-3 in cases with sporadic medullary
Theralizumab (4,304 words) [view diff] exact match in snippet view article find links to article
agonist for, the CD28 receptor of the immune system's T cells. CD28 is the co-receptor for the T cell receptor; It binds to receptors on the interacting partner
DKK2 (479 words) [view diff] exact match in snippet view article find links to article
2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6). Hairy palms and soles GRCh38:
CXCR4 antagonist (320 words) [view diff] exact match in snippet view article find links to article
been targeted by antagonistic substances since being identified as a co-receptor in HIV and assisting the development of cancer. Macrocyclic ligands have
Leronlimab (2,001 words) [view diff] exact match in snippet view article find links to article
replication. It prevents the virus-cell binding at a distinct site in the CCR5 co-receptor without interfering with its natural activity. Unlike other entry inhibitors
Repulsive guidance molecule A (1,134 words) [view diff] exact match in snippet view article find links to article
Repulsive guidance molecule A (RGMa) is a bone morphogenetic protein (BMP) co-receptor of the repulsive guidance molecule family. Together with BMPR1A and BMPR1B
Or83b odorant receptor (681 words) [view diff] exact match in snippet view article find links to article
Or83b, also known as Orco (short for "odorant receptor co-receptor"), is an odorant receptor and the corresponding gene that encodes it. The odorant receptor
Vicriviroc (2,046 words) [view diff] exact match in snippet view article find links to article
increased rate of development of AIDS and death. A focus on the CCR5 co-receptor as a potential target for anti-HIV medications began in 1996 with the
Aurintricarboxylic acid (522 words) [view diff] exact match in snippet view article find links to article
shown to block the binding of the HIV coat molecule gp120 to the CD4 co-receptor on T cells through which it invades.[citation needed] Aurintricarboxylic
ZAP70 (2,769 words) [view diff] exact match in snippet view article find links to article
the TCR co-receptor CD4 (expressed on T helper cells) or CD8 (expressed on cytotoxic T cells) binds to the MHC, activating the co-receptor associated
F2RL2 (902 words) [view diff] exact match in snippet view article find links to article
(2001). "Neutrophil proteases can inactivate human PAR3 and abolish the co-receptor function of PAR3 on murine platelets". Thromb. Haemost. 85 (3): 533–8
Adenoviridae (5,542 words) [view diff] exact match in snippet view article find links to article
with an integrin molecule. It is the co-receptor interaction that stimulates entry of the adenovirus. This co-receptor molecule is αV integrin. Binding to
Syndecan-4 (2,088 words) [view diff] exact match in snippet view article find links to article
bind to FGFs and bring them to the FGF receptor on the same cell. As a co-receptor or regulator, mutated certain proteoglycans could cause severe developmental
Apelin receptor (1,253 words) [view diff] exact match in snippet view article find links to article
2003). "Cell-cell fusion and internalization of the CNS-based, HIV-1 co-receptor, APJ". Virology. 307 (1): 22–36. doi:10.1016/S0042-6822(02)00021-1. PMID 12667811
Monogram Biosciences (195 words) [view diff] case mismatch in snippet view article find links to article
Progression [1] Four Studies Affirm Significance Of Monogram's Trofile(TM) HIV Co-Receptor Tropism Assay [2] Accuracy of Monogram's Trofile Assay in Determining
CD14 (846 words) [view diff] exact match in snippet view article find links to article
was the first described pattern recognition receptor. CD14 acts as a co-receptor (along with the Toll-like receptor TLR 4 and MD-2) for the detection
Hemojuvelin (1,834 words) [view diff] exact match in snippet view article find links to article
hemojuvelin interacts with bone morphogenetic protein (BMP), possibly as a co-receptor, and may signal via the SMAD pathway to regulate hepcidin expression
Lymphocyte-activation gene 3 (6,644 words) [view diff] exact match in snippet view article find links to article
"Atypical motifs in the cytoplasmic region of the inhibitory immune co-receptor LAG-3 inhibit T cell activation". Journal of Biological Chemistry. 294
CD160 (993 words) [view diff] exact match in snippet view article find links to article
Marie-Cardine A, Boumsell L, Bensussan A (2002). "BY55/CD160 acts as a co-receptor in TCR signal transduction of a human circulating cytotoxic effector
Myofibroblast (1,066 words) [view diff] exact match in snippet view article find links to article
differentiation pathway have been described, including hyaluronan and CD44 co-receptor activation of EGFR. In many organs like liver, lung, and kidneys, they
Gp41 (1,709 words) [view diff] exact match in snippet view article find links to article
stabilized by a non-covalent bond with gp120. Gp120 binds to a CD4 and a co-receptor (CCR5 or CXCR4), found on susceptible cells such as Helper T cells and
Intermediate mesoderm (1,553 words) [view diff] exact match in snippet view article find links to article
metanephrogenic blastema activates the receptor tyrosine kinase RET, via the co-receptor GFRα1 and triggers outgrowth of Ret positive cells from the nephric duct
Fibroblast growth factor receptor (827 words) [view diff] exact match in snippet view article find links to article
fibroblast growth factor receptor 1 regulates ligand and heparan sulfate co-receptor binding". The Journal of Biological Chemistry. 281 (37): 27178–89. doi:10
Christopher E. Rudd (898 words) [view diff] exact match in snippet view article find links to article
kinase glycogen synthase kinase-3 (GSK-3) to down-regulate the inhibitory co-receptor programmed cell death-1 (PD-1) in cancer immunotherapy. Rudd's work has
GPR15 (1,503 words) [view diff] exact match in snippet view article find links to article
anti-inflammatory function in mice. Human GPR15 was originally cloned as a co-receptor for HIV or the simian immunodeficiency virus. HIV-induced activation
Low-affinity nerve growth factor receptor (4,235 words) [view diff] exact match in snippet view article find links to article
rather than trimerize, because of its ability to act as a tyrosine kinase co-receptor, and because the neurotrophins are structurally unrelated to the ligands
CD278 (1,853 words) [view diff] exact match in snippet view article find links to article
Schneider H (Jul 2003). "Unifying concepts in CD28, ICOS and CTLA4 co-receptor signalling". Nature Reviews. Immunology. 3 (7): 544–56. doi:10.1038/nri1131
CCR3 (gene) (1,447 words) [view diff] exact match in snippet view article
possibly at sites of parasitic infection. It is also known to be an entry co-receptor for HIV-1, enabling viral infection in cells that also express CD4, the
CMKLR1 (1,262 words) [view diff] exact match in snippet view article find links to article
"Characterization of the human chemerin receptor--ChemR23/CMKLR1--as co-receptor for human and simian immunodeficiency virus infection, and identification
DKK1 (1,943 words) [view diff] exact match in snippet view article find links to article
the Wnt/β-catenin signalling pathway that acts by isolating the LRP6 co-receptor so that it cannot aid in activating the WNT signaling pathway. DKK1 was
SLAMF1 (2,008 words) [view diff] exact match in snippet view article find links to article
lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM". Nature. 395 (6701): 462–469. Bibcode:1998Natur.395..462S. doi:10
Interleukin 37 (1,707 words) [view diff] exact match in snippet view article find links to article
thus extracellular IL-37 can interact with IL-18 receptor (IL-18R) and co-receptor IL-1 receptor 8 (IL-1R8). The affinity of IL-37b to IL-18R alpha subunit
Neurturin (1,468 words) [view diff] exact match in snippet view article find links to article
phosphatidylinositol (GPI)-linked protein. Neurturin preferentially binds to the GFRα2 co-receptor. Upon assembly of the complex, specific tyrosine residues are phosphorylated
Management of HIV/AIDS (15,827 words) [view diff] exact match in snippet view article find links to article
available agents in this class. Maraviroc works by targeting CCR5, a co-receptor located on human helper T-cells. Caution should be used when administering
GSK-3 (5,581 words) [view diff] exact match in snippet view article find links to article
Tbet (Tbx21) and an inhibition of the transcription of the inhibitory co-receptor programmed cell death-1 (PD-1) on T-cells. GSK-3 inhibitors increased
Adeno-associated virus (8,517 words) [view diff] exact match in snippet view article find links to article
The first functions as a primary receptor, while the latter two have a co-receptor activity and enable AAV to enter the cell by receptor-mediated endocytosis
DC-SIGN (2,087 words) [view diff] exact match in snippet view article find links to article
high-mannose-containing glycoproteins on their surface, and can function as a co-receptor for several viruses such as HIV and Hepatitis C. Binding to DC-SIGN can
Reticulon 4 receptor (1,577 words) [view diff] exact match in snippet view article find links to article
R, He Z (November 2002). "P75 interacts with the Nogo receptor as a co-receptor for Nogo, MAG and OMgp". Nature. 420 (6911): 74–8. Bibcode:2002Natur
Inositol pentakisphosphate (234 words) [view diff] exact match in snippet view article find links to article
(2010). "Jasmonate perception by inositol phosphate-potentiated COI1-JAZ co-receptor". Nature. 468 (7322): 400–405. Bibcode:2010Natur.468..400S. doi:10.1038/nature09430
Brassinosteroid insensitive-1 (975 words) [view diff] exact match in snippet view article find links to article
the brassinosteroid molecule and for this reason they are considered a co-receptor. BRI1 and BAK1 sequentially phosphorylate each other in their kinase
Coolidge effect (3,895 words) [view diff] exact match in snippet view article find links to article
melanogaster, which processed a mutated Orco gene, which codes for a co-receptor that is important for olfaction. The result of this type of mutation
Plerixafor (1,658 words) [view diff] exact match in snippet view article find links to article
role in the blocking of CXCR4, a chemokine receptor which acts as a co-receptor for certain strains of HIV (along with the virus's main cellular receptor
Subtypes of HIV (3,870 words) [view diff] exact match in snippet view article find links to article
reverse transcriptase inhibitors (NNRTIs) with the addition of CCR5 co-receptor antagonists and fusion inhibitors. Choice of initial and/or second-line
FGF19 (2,557 words) [view diff] exact match in snippet view article find links to article
Xu J, Veniant MM, Li YS, Lindberg R, Chen JL, Tian H, Li Y (2007). "Co-receptor requirements for fibroblast growth factor-19 signaling". J. Biol. Chem
Nodal signaling pathway (3,355 words) [view diff] exact match in snippet view article find links to article
pathway. During Nodal transportation to the extracellular space, the Nodal co-receptor captures the Nodal precursor in lipid rafts and once in the cell surface
Sulfatide (5,620 words) [view diff] exact match in snippet view article find links to article
conformation allows the gp120 complex to interact with the chemokine co-receptor and the insertion of the fusion peptide, gp41, into the membrane of the
Australian bat lyssavirus (2,576 words) [view diff] exact match in snippet view article find links to article
spike protein either binds to a highly specific host receptor or uses a co-receptor in lipid rafts. Some of the proposed receptors include nicotinic acetylcholine
HFE (gene) (2,309 words) [view diff] exact match in snippet view article
Molecular function peptide antigen binding beta-2-microglobulin binding co-receptor binding protein binding transferrin receptor binding signaling receptor
Structure and genome of HIV (3,936 words) [view diff] exact match in snippet view article find links to article
is responsible for binding to its primary host receptor, CD4, and its co-receptor (mainly CCR5 or CXCR4), leading to viral entry into its target cell.
Host tropism (2,537 words) [view diff] exact match in snippet view article find links to article
the gp120 and gp41 proteins on its surface. HIV also requires a second co-receptor along with the CD4-gp120 complex to enter the target cells - either CCR5
Legionella pneumophila (4,495 words) [view diff] exact match in snippet view article find links to article
structure helps prevent interaction with a common LPS immune system co-receptor, CD14. There is also a correlation between an LPS with a high molecular-weight
Retinal ganglion cell (3,522 words) [view diff] exact match in snippet view article find links to article
Boc, or Brother of CDO (CAM-related/downregulated by oncogenes), a co-receptor for Shh that influences Shh signaling through Ptch1, seems to mediate
Brassinosteroid (1,777 words) [view diff] exact match in snippet view article find links to article
under the same conditions. BRs are perceived at the cell membrane by a co-receptor complex, comprising brassinosteroid insensitive-1 (BRI1) and BRI1-associated
WNT9B (444 words) [view diff] exact match in snippet view article find links to article
ontology Molecular function frizzled binding signaling receptor binding co-receptor binding receptor ligand activity Cellular component extracellular region
Cytochrome P450 (6,613 words) [view diff] exact match in snippet view article find links to article
considered activated. Then, JA-Ile synthesis leads to the assembly of the co-receptor complex compo`sed of COI1 and several JAZ proteins. Under low JA-Ile
Dally (gene) (825 words) [view diff] exact match in snippet view article
critical role in the process of modification of dally. Dally works as a co-receptor of some secreted signaling molecules as fibroblast growth factor, vascular
NEO1 (689 words) [view diff] exact match in snippet view article find links to article
Gene ontology Molecular function co-receptor binding protein binding signaling receptor activity Cellular component integral component of membrane plasma
Restriction enzyme (5,842 words) [view diff] exact match in snippet view article find links to article
Phase I clinical trial of ZFN for the targeted abolition of the CCR5 co-receptor for HIV-1 has been undertaken. Others have proposed using the bacteria
T cell (9,029 words) [view diff] exact match in snippet view article find links to article
commonly termed double-negative, as they express neither the CD4 nor CD8 co-receptor. The newly arrived CLP cells are CD4−CD8−CD44+CD25−ckit+ cells, and are
Neurotrophic factors (1,784 words) [view diff] exact match in snippet view article find links to article
GDNF uses a receptor tyrosine kinase and a high-affinity ligand-binding co-receptor GFRα. GDNF has an especially strong affinity for dopaminergic (DA) neurons
Robert Gallo (3,682 words) [view diff] exact match in snippet view article find links to article
(conceptually) in the advances that led to the discovery of the cell co-receptor for HIV infection, because this is the molecule the HIV inhibitory molecules
Restriction modification system (2,623 words) [view diff] exact match in snippet view article find links to article
Phase I clinical trial of ZFN for the targeted abolition of the CCR5 co-receptor for HIV-1 has been undertaken. R-M systems are major players in the co-evolutionary
Leslie B. Vosshall (1,395 words) [view diff] exact match in snippet view article find links to article
In addition, Vosshall and her associates discovered ORCO, a mosquito co-receptor responsible for preference for humans over non-human animals and sensitivity
Lipopolysaccharide binding protein (1,454 words) [view diff] exact match in snippet view article find links to article
protein has been shown to interact with CD14, TLR2, TLR4 and the co-receptor MD-2. GRCh38: Ensembl release 89: ENSG00000129988 - Ensembl, May 2017
CBL (gene) (3,814 words) [view diff] exact match in snippet view article
Rosenstein Y (January 2001). "Regulation of Cbl molecular interactions by the co-receptor molecule CD43 in human T cells". J. Biol. Chem. 276 (1): 729–37. doi:10
Transferrin receptor 2 (952 words) [view diff] exact match in snippet view article find links to article
Gene ontology Molecular function transferrin receptor activity co-receptor binding protein binding Cellular component cytoplasm integral component of
WNT3A (1,660 words) [view diff] exact match in snippet view article find links to article
function protein domain specific binding signaling receptor binding co-receptor binding frizzled binding protein binding transcription coactivator activity
General-purpose computing on graphics processing units (6,690 words) [view diff] exact match in snippet view article find links to article
Gorlatch, S; Heider, D (15 November 2014). "gCUP: rapid GPU-based HIV-1 co-receptor usage prediction for next-generation sequencing". Bioinformatics. 30
Shahid Jameel (1,930 words) [view diff] exact match in snippet view article find links to article
India and he continues his work focusing on HIV accessory proteins, HIV co-receptor dynamics, hepatitis B, X and SARS virus 3a proteins. He headed the group
Danger model (1,153 words) [view diff] exact match in snippet view article find links to article
molecules (MHC2). Helper T cells recognize these by expressing the CD4 co-receptor. The activation of a resting helper T cell causes it to release cytokines
GDNF family of ligands (1,125 words) [view diff] exact match in snippet view article find links to article
dimer, a receptor tyrosine kinase molecule RET, and a cell surface-bound co-receptor that is a member of the GFRα protein family. The primary ligands for
History of HIV/AIDS (13,385 words) [view diff] exact match in snippet view article find links to article
viral entry, and contain many activated T cells expressing the CCR5 co-receptor, the main cell targets of HIV. Sousa et al. use molecular dating techniques
Semaphorin-3A (1,729 words) [view diff] exact match in snippet view article find links to article
signaled through receptor complexes containing Neuropilin-1 (NRP1) and a co-receptor. One of the first identified intracellular messenger required for the
Paul Bieniasz (989 words) [view diff] exact match in snippet view article find links to article
mediated by multiple regions within both the viral envelope and the CCR-5 co-receptor". The EMBO Journal. 16 (10): 2599–609. doi:10.1093/emboj/16.10.2599.
LRRK2 (1,929 words) [view diff] exact match in snippet view article find links to article
activity signaling receptor complex adaptor activity clathrin binding co-receptor binding transferase activity GTPase activator activity protein kinase
Oxymatrine (839 words) [view diff] exact match in snippet view article find links to article
the main signaling receptors involved in this pathway is the TGF-β1 co-receptor (complex of type I and type II receptors), which acts as a trans-membrane
CD4 immunoadhesin (2,863 words) [view diff] exact match in snippet view article find links to article
receptor by HIV to attach to the surface of target cells. HIV then uses a co-receptor, either CCR5 or CXCR4, to facilitate entry into the cell. The ability
Metastatic breast cancer (5,270 words) [view diff] exact match in snippet view article find links to article
glycoprotein which binds to integrins and other RGD ligands and is a co-receptor for TGF-beta. Brain-metastatic breast-tumor cells express endoglin in
SH2D1A (1,846 words) [view diff] exact match in snippet view article find links to article
lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM". Nature. 395 (6701): 462–9. Bibcode:1998Natur.395..462S. doi:10
DKK3 (918 words) [view diff] exact match in snippet view article find links to article
Gene ontology Molecular function co-receptor binding receptor antagonist activity Cellular component extracellular region extracellular space Biological
CCL3L1 (1,447 words) [view diff] exact match in snippet view article find links to article
(CCBP2 or D6) and chemokine (C-C motif) receptor 5 (CCR5). CCR5 is a co-receptor for HIV, and binding of CCL3L1 to CCR5 inhibits HIV entry. Furthermore
DKK4 (436 words) [view diff] exact match in snippet view article find links to article
Gene ontology Molecular function molecular function co-receptor binding receptor antagonist activity Cellular component extracellular region cellular
YWHAQ (1,999 words) [view diff] exact match in snippet view article find links to article
Rosenstein Y (January 2001). "Regulation of Cbl molecular interactions by the co-receptor molecule CD43 in human T cells". J. Biol. Chem. 276 (1): 729–37. doi:10
Discovery and development of nucleoside and nucleotide reverse-transcriptase inhibitors (3,232 words) [view diff] exact match in snippet view article find links to article
reverse-transcriptase inhibitors, protease inhibitors, entry inhibitors, co-receptor inhibitors and integrase inhibitors. The reverse transcriptase of HIV-1
2F5 antibody (1,646 words) [view diff] exact match in snippet view article find links to article
that associates with gp120 to bind the virus to CD4 and a chemokine co-receptor on the target cell and infect it. 2F5 binds to the variable regions of
Keiko Torii (1,246 words) [view diff] exact match in snippet view article find links to article
(September 2018). "Phosphocode-dependent functional dichotomy of a common co-receptor in plant signalling". Nature. 561 (7722): 248–252. Bibcode:2018Natur
PIK3R1 (3,132 words) [view diff] exact match in snippet view article find links to article
activation of phosphoinositide 3-kinase and Akt via the ErbB2/ErbB3 co-receptor". J. Biol. Chem. 276 (45): 42153–61. doi:10.1074/jbc.M102079200. PMID 11546794
Brassinolide (1,757 words) [view diff] exact match in snippet view article find links to article
inhibitor (BKI1) prevents the BRI1 receptor from interacting with the BAK1 co-receptor. This prevents the activation of BIN2, causing BZR1 and BES1 to be chemically
Intravascular lymphomas (4,733 words) [view diff] exact match in snippet view article find links to article
lymphoma as evidenced by the neoplastic cells' expression of T-cell co-receptor proteins (e.g. CD3, CD4, and/or CD8) as well as EBV marker proteins and/or
Vanessa Ruta (1,107 words) [view diff] exact match in snippet view article find links to article
Drosophila and solved the structure of the invertebrate olfactory receptor co-receptor (Orco). Her work on the structure of insect odorant receptors—a potential
Insect olfaction (1,598 words) [view diff] exact match in snippet view article find links to article
to an odorant binding protein which transports it to a receptor and co-receptor (Orco) team on the surface of the olfactory receptor neuron (ORN). This
Cédric Blanpain (2,716 words) [view diff] exact match in snippet view article find links to article
Parmentier lab characterized the CCR5 GPCR and discovered its role as a co-receptor in HIV infection. Cedric Blanpain earned his PhD in 2001 for his work
Paula Cannon (389 words) [view diff] exact match in snippet view article find links to article
and Harvard Cannon's recent work is aimed at disrupting the CCR viral co-receptor, CCR5, using zinc finger nucleases(ZFNs). She also studies SARS-CoV-2
Alan M. Krensky (1,082 words) [view diff] exact match in snippet view article find links to article
AM, Norment AM, Littman DR, Parham P: A binding site for the T cell co-receptor, CD8, on the alpha3 domain of HLA-A2. Nature. 1990; 345: 41-46. Salter
Glypican 3 (2,626 words) [view diff] exact match in snippet view article find links to article
triggers downstream signaling. The core protein of GPC3 may serve as a co-receptor or a receiver for Wnt. A cysteine-rich domain at the N-lobe of GPC3 has
Botrytis–induced kinase 1 (1,118 words) [view diff] exact match in snippet view article find links to article
kinase (RLCK) that associates with a cell-surface receptor, FLS2, and a co-receptor kinase, BAK1 to transduce signals when a PAMP is detected. In order for
Antonio Siccardi (685 words) [view diff] exact match in snippet view article find links to article
Littman, D. R.; Fenyö, E. M.; Lusso, P (1997). "In vivo evolution of HIV-1 co-receptor usage and sensitivity to chemokine-mediated suppression". Nature Medicine
C-C motif chemokine ligand 3 like 3 (218 words) [view diff] exact match in snippet view article find links to article
binding protein 2 and chemokine (C-C motif) receptor 5 (CCR5). CCR5 is a co-receptor for HIV, and binding of this protein to CCR5 inhibits HIV entry. The
Biochemical cascade (11,417 words) [view diff] exact match in snippet view article find links to article
The canonical signaling involves binding of Wnt to Frizzled and LRP5 co-receptor, leading to GSK3 phosphorylation and inhibition of β-catenin degradation
Common symbiosis signaling pathway (4,792 words) [view diff] exact match in snippet view article find links to article
has a prominent role in perception process and it is thought to be a co-receptor of MFR. Other plants such as rice may employ different mechanisms using
Peritubular myoid cell (1,366 words) [view diff] exact match in snippet view article find links to article
Following this, GDNF binds GFRA1 on spermatogonial stem cells, and RET co-receptor (a transmembrane tyrosine kinase) is consequently signalled throughout
Mammalian orthoreovirus (2,241 words) [view diff] exact match in snippet view article find links to article
Sialic acid, resident within the respiratory system of most mammals is a co-receptor for Mammalian orthoreovirus Type 3 (Dearing). After binding to the receptors
Collapsin response mediator protein family (2,518 words) [view diff] exact match in snippet view article find links to article
plexin directly. Instead, it interacts with neuropilins as ligand-binding co-receptor for plexin and releases plexin-based signaling. The signal transduction
Chemosensory speciation (1,424 words) [view diff] exact match in snippet view article find links to article
(OR) for proper antennal lobe (AL) function; a gene knockout of an OR co-receptor drastically impaired AL development in the clonal raider ant, Ooceraea
Endothelial cell tropism (3,482 words) [view diff] exact match in snippet view article find links to article
cell surface receptors associated with viral entry include ACE2 and co-receptor TMPRSS2. TMPRSS2 is needed to cleave the spike protein for viral fusion
GAS1 (2,234 words) [view diff] exact match in snippet view article find links to article
Schueler-Furman O, Glick E, Segovia J, Linial M (February 2006). "Is GAS1 a co-receptor for the GDNF family of ligands?". Trends in Pharmacological Sciences
List of people associated with University College London (12,791 words) [view diff] exact match in snippet view article find links to article
Director of the Wohl Virus Research Centre, discovered that CD4 is the co-receptor for HIV Semir Zeki, Professor of Neurology, proponent for the role of
Breast cancer classification (9,503 words) [view diff] exact match in snippet view article find links to article
between genetic subtypes. Tumors overexpressing the Wnt signaling pathway co-receptor low-density lipoprotein receptor-related protein 6 (LRP6) may represent
MAPK networks (1,223 words) [view diff] exact match in snippet view article find links to article
colleges claim “AvrPto and AvrPtoB interact with the FLS2 receptor and its co-receptor BAK1. AvrPtoB catalyzes the polyubiquitination and subsequent proteasome-dependent
Zinc finger nuclease treatment of HIV (3,400 words) [view diff] exact match in snippet view article find links to article
; Petropoulos, C.J.; Whitcomb, J.M. (2005). "Assessing ch vbgemokine co-receptor usage in HIV". Curr. Opin. Infect. Dis. 18 (1): 9–15. doi:10
Catch bond (5,492 words) [view diff] exact match in snippet view article find links to article
immune recognition: TCR docking topologies, mechanotransduction, and co-receptor function". Immunological Reviews. 250 (1): 102–19. doi:10.1111/j.1600-065X
Lacritin (4,889 words) [view diff] exact match in snippet view article find links to article
(GPCR). A candidate GPCR is under study. Syndecan-1 likely serves as a co-receptor. Binding lacritin may improve its GPCR affinity. Lacritin survival signaling
Stem-cell niche (8,002 words) [view diff] exact match in snippet view article find links to article
expansion of mouse SSCs in culture. However, the GDNF receptor c-RET and co-receptor GFRa1 are not solely expressed on the SSCs but also on Apaired and Aaligned
T cell/histiocyte-rich large B-cell lymphoma (2,173 words) [view diff] exact match in snippet view article find links to article
cells as indicated by their expression of T-cell receptor, CD8 T-cell co-receptor, and CD5 cell surface proteins. And, the histiocytes in these lesions
Off-target genome editing (6,822 words) [view diff] exact match in snippet view article find links to article
ZFN disables the C-C chemokine receptor 5 (CCR5) gene, which encodes a co-receptor that is used by the HIV virus to enter the cell. As a result of the high
Secreted frizzled-related protein 1 (6,317 words) [view diff] exact match in snippet view article find links to article
binding of Wnt to a receptor complex encompassing a Fz receptor and LRP co-receptor. After Wnt binds, an intracellular protein named Dishevelled (Dvl) is
Georgette D. Kanmogne (2,345 words) [view diff] exact match in snippet view article find links to article
cells and cortical neurons for susceptibility to HIV-1 infection and co-receptor expression". Journal of Neurovirology. 6 (6): 519–28. doi:10.3109/13550280009091952
Malú G. Tansey (2,796 words) [view diff] exact match in snippet view article find links to article
proper GFL signalling, RET needed to be interacting with a GPI-linked co-receptor associated with a lipid raft in order for proper functioning. They further