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Longer titles found: Viral vector vaccine (view), Retinal gene therapy using lentiviral vectors (view), Lentiviral vector in gene therapy (view)

searching for Viral vector 89 found (274 total)

alternate case: viral vector

Zika virus vaccine (1,269 words) [view diff] no match in snippet view article find links to article

A Zika virus vaccine is designed to prevent the symptoms and complications of Zika virus infection in humans. As Zika virus infection of pregnant women

Bovine papular stomatitis (1,752 words) [view diff] exact match in snippet view article find links to article

skin disorders. BPSV has several advantageous features for use in a viral vector vaccine: It can carry large amounts of foreign DNA, is well-adapted to

Jesse Gelsinger (634 words) [view diff] exact match in snippet view article find links to article

having suffered a massive immune response triggered by the use of the viral vector to transport the gene into his cells, leading to multiple organ failure

Thermo Fisher Scientific (4,275 words) [view diff] case mismatch in snippet view article find links to article

Acquires Viral Vector Manufacturing Business from Novasep". BioSpace. "Thermo Fisher Takes Deep Dive into Cell and Gene Therapy with Viral Vector Business

Gene-activated matrix (183 words) [view diff] exact match in snippet view article find links to article

reproducible tissue regeneration. The matrix can be modified by incorporating a viral vector, mRNA or DNA bound to a delivery system, or a naked plasmid. Bonadio

Vaccine shedding (1,414 words) [view diff] exact match in snippet view article find links to article

vaccine technologies such as inactivated vaccine (killed-virus vaccines), viral vector vaccine, RNA vaccines (that contain no virus), or subunit vaccines (a

Mydicar (814 words) [view diff] exact match in snippet view article find links to article

The SERCA2a gene is delivered to the heart via an adeno-associated viral vector. Using the α-myosin heavy chain gene promoter in the cardiac muscle cells

Oncogene (3,173 words) [view diff] exact match in snippet view article find links to article

initially found to induce cancer in animals when they are introduced through viral vector infection, which carries genetic information from a prior host cell.

Ixoberogene soroparvovec (159 words) [view diff] exact match in snippet view article find links to article

Biotechnologies for wet age-related macular degeneration. It is delivered via the viral vector AAV.7m8. Gelfman, Claire M.; Grishanin, Ruslan; Bender, Kristina Oresic;

Animal models of Parkinson's disease (3,147 words) [view diff] exact match in snippet view article find links to article

fibrils to the SNpc, thus, lacking abundant neurodegeneration. Through the viral vector-mediated delivery of alpha-synuclein, the vectors can target the dopaminergic

Transposase (2,547 words) [view diff] exact match in snippet view article find links to article

Hackett, P.B. (2011). The Sleeping Beauty transposon system – A non-viral vector for gene therapy. Hum. Mol. Genet. (in press)Aronovich EL, McIvor RS

Marylyn Addo (1,268 words) [view diff] exact match in snippet view article find links to article

disease and the MERS coronavirus EMC/2012. She is currently developing a viral vector based COVID-19 vaccine. Addo is the daughter of a Ghanaian father and

Novasep (347 words) [view diff] exact match in snippet view article find links to article

headquarters was moved from Pompey in Lorraine to Lyon. Novasep's Belgium viral vector manufacturing division, Henogen, was sold to Thermo Fisher for €725 million

Etranacogene dezaparvovec (791 words) [view diff] exact match in snippet view article find links to article

adeno-associated virus vector-based gene therapy which consists of a viral vector carrying a gene for clotting Factor IX. The gene is expressed in the

Intravitreal gene therapy (864 words) [view diff] exact match in snippet view article find links to article

genes directly into the vitreous humor of the eye. This method uses a viral vector, often an adeno-associated virus (AAV), to carry genetic material into

Transflammation (690 words) [view diff] exact match in snippet view article find links to article

These conclusions suggest that transcription factor transfer by the viral vector enhances reprogramming efficiency and processes that are involved in

Adrian V. S. Hill (1,071 words) [view diff] exact match in snippet view article find links to article

partial efficacy using Adenovirus and Modified vaccinia Ankara (MVA) viral vector vaccines in a prime-boost regime. From 2005 he has played a leading role

Jean Bennett (2,354 words) [view diff] exact match in snippet view article find links to article

testing visual function using virtual mobility tests, (2019). Trans-viral vector mediated gene transfer to the retina, (abandoned). Modified AAV8 capsid

Short hairpin RNA (1,259 words) [view diff] exact match in snippet view article find links to article

developed acute T-cell leukaemia. This was determined to have been caused by viral vector insertion location. Potential oversaturation of RISC is also a problem

Transposon mutagenesis (2,213 words) [view diff] exact match in snippet view article find links to article

Sleeping Beauty transposon system (SBTS) is the first successful non-viral vector for incorporation of a gene cassette into a vertebrate genome. Up until

Gene therapy for color blindness (2,336 words) [view diff] exact match in snippet view article find links to article

Gene expression could stabilize if a sufficiently high dose of the viral vector is given. In 2009, adult dichromatic squirrel monkeys were converted

Hydrodynamic delivery (1,012 words) [view diff] exact match in snippet view article find links to article

Alternative methods can be used to insert genes into an organism without a viral vector. These can be split into physical and chemical techniques. Physical methods:

Gene therapy of the human retina (4,992 words) [view diff] exact match in snippet view article find links to article

Bennett J (December 2001). "Exchange of surface proteins impacts on viral vector cellular specificity and transduction characteristics: the retina as

Vole (2,798 words) [view diff] exact match in snippet view article find links to article

behavior to resemble that of prairie voles in experiments in which a viral vector was used to increase a single gene's expression within a particular brain

Human foamy virus (1,310 words) [view diff] exact match in snippet view article find links to article

(endoplasmic reticulum membrane); it results in low extracellular titers of the viral vector. Meiering, Christopher D.; Maxine L. Linial (January 2001). "Historical

Alipogene tiparvovec (1,171 words) [view diff] exact match in snippet view article find links to article

three patients for €1 each. The adeno-associated virus serotype 1 (AAV1) viral vector delivers an intact copy of the human lipoprotein lipase (LPL) gene to

Michael W. Bevan (821 words) [view diff] exact match in snippet view article find links to article

"Expression of a flower-specific Myb protein in leaf cells using a viral vector causes ectopic activation of a target promoter". Proceedings of the National

Academy of Military Medical Sciences (1,008 words) [view diff] exact match in snippet view article find links to article

66% efficacy in a global trial. Convidecia is also similar to other viral vector vaccines like the Oxford–AstraZeneca vaccine and Sputnik V vaccine. Its

Mirus Bio (582 words) [view diff] exact match in snippet view article find links to article

mouse liver; new chemistries for transfection; development of a non-viral vector providing sustained liver-specific transgene expression for more than

Neurturin (1,477 words) [view diff] exact match in snippet view article find links to article

Ceregene sponsored a double-blind phase II clinical trial of CERE-120, a viral vector mediated gene transfer drug that allows for the continuous delivery of

Genetically modified sperm (635 words) [view diff] exact match in snippet view article find links to article

inserted into living cells in order to change how proteins are created. A viral vector is often used to deliver the gene of interest to the chromosomes in the

ATC code J07 (708 words) [view diff] exact match in snippet view article find links to article

33, 45, 52, 58) J07BN01 Covid-19, RNA-based vaccine J07BN02 Covid-19, viral vector, non-replicating J07BN03 Covid-19, inactivated virus J07BN04 Covid-19

Allotopic expression (725 words) [view diff] exact match in snippet view article find links to article

areas. The company suspected the outcome was due to the transferal of viral vector DNA from the treated eye to the untreated eye of each patient, and thus

Orthobunyavirus (1,679 words) [view diff] exact match in snippet view article find links to article

paraensis). Although transmission by ticks and bed bugs may also occur. Viral vector preference is generally strict, with only a one or very small number

Conditional gene knockout (1,292 words) [view diff] exact match in snippet view article find links to article

recombination and gene trapping. Both methods usually have a modified viral vector or a linear fragment as the mode of transportation of the artificial

MVA-B (1,047 words) [view diff] exact match in snippet view article find links to article

titled Gag, Pol, Nef and Env. An improved version of the recombinant viral vector, which was titled MVA-B ΔA40R, was created and published in February

Sudhanshu Vrati (1,386 words) [view diff] exact match in snippet view article find links to article

December 2017. "Dna encoding ovine adenovirus (oav287) and its use as a viral vector". Google Patents. 12 December 2017. Retrieved 12 December 2017. "Biological

Obsidian Kingdom (2,344 words) [view diff] case mismatch in snippet view article find links to article

2005–present Members Rider G Omega Ojete Mordaza II Om Rex Orale Jade Riot Cul Viral Vector Lips Past members Eaten Roll I Seerborn Ape Tot Zer0 Æmeour Íggdrasil

Stanley Center for Psychiatric Research at Broad Institute (987 words) [view diff] case mismatch in snippet view article find links to article

Neurobiology Jen Pan Director, Translational Research Jeff Cottrell Director, Medicinal Chemistry Florence Wagner Director, Viral Vector Engineering Ben Deverman

LEAPER gene editing (783 words) [view diff] exact match in snippet view article find links to article

achieved when LEAPER editing using arRNA151 is delivered via a plasmid or viral vector or as a synthetic oligonucleotide, though this efficiency varied significantly

Cloning vector (2,517 words) [view diff] exact match in snippet view article find links to article

insertional mutagenesis caused by integration into host chromosomes by viral vector. Viruses that infect plant and animal cells have also been manipulated

Stanley Center for Psychiatric Research at Broad Institute (987 words) [view diff] case mismatch in snippet view article find links to article

Neurobiology Jen Pan Director, Translational Research Jeff Cottrell Director, Medicinal Chemistry Florence Wagner Director, Viral Vector Engineering Ben Deverman

Viviana Gradinaru (1,054 words) [view diff] exact match in snippet view article find links to article

These technologies include optogenetics and CLARITY. She developed viral vector screening methods to create gene delivery vehicles that can cross the

Video game piracy (2,152 words) [view diff] case mismatch in snippet view article find links to article

Moshirnia, Andrew (2018-01-01). "Typhoid Mario: Video Game Piracy as Viral Vector and National Security Threat". 93 Indiana Law Journal 975 (2018). 93

Sepik virus (2,022 words) [view diff] exact match in snippet view article find links to article

arboviruses, is transmitted from a host reservoir to humans through a viral vector. Some arboviruses can be maintained in a population with minimal input

Spark Therapeutics (869 words) [view diff] exact match in snippet view article find links to article

partnership with Pfizer. Fidanacogene elaparvovec is an adeno-associated viral vector which is designed to transfer a working copy of the Factor IX gene into

BioMarin Pharmaceutical (1,679 words) [view diff] exact match in snippet view article find links to article

Valoctocogene roxaparvovec (branded as Roctavian) is an adeno-associated viral vector for treatment of hemophilia A that aims to transfer a working copy of

Molecular biology (5,538 words) [view diff] exact match in snippet view article find links to article

naked DNA, conjugation via cell-cell contact or by transduction via viral vector. Introducing DNA into eukaryotic cells, such as animal cells, by physical

R. Jude Samulski (948 words) [view diff] exact match in snippet view article find links to article

current FDA-approved AAV gene therapies. His work demonstrated AAV2 as a viral vector for gene therapy which led to the first U.S. Patent for inserting genes

SEPT5 (1,358 words) [view diff] exact match in snippet view article find links to article

(October 2003). "Dopamine-dependent neurodegeneration in rats induced by viral vector-mediated overexpression of the parkin target protein, CDCrel-1". Proceedings

Vision rehabilitation (1,968 words) [view diff] exact match in snippet view article find links to article

treat visual impairments. In this approach, DNA is modified through a viral vector, and then cells related to vision cease translating faulty proteins.

Leaf Huang (297 words) [view diff] exact match in snippet view article find links to article

therapy and targeted drug delivery. He has pioneered the liposome non-viral vector and has designed and manufactured the cationic lipid vector for the first

Tobacco rattle virus (1,796 words) [view diff] exact match in snippet view article find links to article

such as alfalfa, to compete against weeds that may otherwise harbor the viral vector. In contrast, nightshade is a very problematic weed as it is an ideal

PerkinElmer (3,291 words) [view diff] exact match in snippet view article find links to article

the company announced it would acquire SIRION Biotech, a specialist in viral vector gene delivery methods. In July the business announced it would acquire

Myzus persicae (2,984 words) [view diff] exact match in snippet view article find links to article

different plant viruses, thus being the world's most versatile aphid viral vector. One useful control measure is to take advantage of the negative taxis

Programmed cell death protein 1 (4,995 words) [view diff] exact match in snippet view article find links to article

a role in negatively regulating CD8+ T cell responses, using an LCMV viral vector model of chronic infection, Rafi Ahmed's group showed that the PD-1-PD-L1

Optogenetics (11,917 words) [view diff] exact match in snippet view article find links to article

cells is challenging. A popular approach is to introduce an engineered viral vector that contains the optogenetic actuator gene attached to a specific promoter

Gene therapy in Parkinson's disease (1,828 words) [view diff] exact match in snippet view article find links to article

impact the development of the disease. There have been explored several viral vector-based gene delivery system that interfere with α- synuclein expression

Christine Rollier (732 words) [view diff] exact match in snippet view article find links to article

joined the Oxford Vaccine Group. She was interested in the design of viral vector vaccines specifically for bacterial diseases. Rollier focused on bacterial

Adherent culture (898 words) [view diff] exact match in snippet view article find links to article

"Adherent versus suspension based platforms: what is the near future of viral vector manufacturing?". BioInsights. Retrieved 2022-12-02. Kang, Wonmo; McNaughton

Glioma (6,986 words) [view diff] exact match in snippet view article find links to article

soon. Strains of Newcastle disease virus have also been used to create viral vector vaccine candidates against Ebola and Covid-19. Torticollis in foul shows

Zoonosis (7,184 words) [view diff] exact match in snippet view article find links to article

attenuated vaccines. There are also new vaccine technologies such as viral vector vaccines and DNA/RNA vaccines, which include many of the COVID-19 vaccines

Onasemnogene abeparvovec (2,436 words) [view diff] exact match in snippet view article find links to article

transgene along with synthetic promoters. Upon administration, the AAV9 viral vector delivers the SMN1 transgene to the affected motor neurons, where it leads

Self-administration (3,793 words) [view diff] exact match in snippet view article find links to article

previously exposed to cocaine for extended periods. Animals infected with a viral vector overexpressing miR-212 in the dorsal striatum produced the same initial

Suzanne Dickson (754 words) [view diff] exact match in snippet view article find links to article

studies in rats and transgenic mice and includes behavioural tasks, viral vector mapping, chemogenetics and RNAscope. Dickson is President and Executive

Genomic library (3,403 words) [view diff] exact match in snippet view article find links to article

above outlined steps. After a genomic library is constructed with a viral vector, such as lambda phage, the titer of the library can be determined. Calculating

Expression vector (4,182 words) [view diff] exact match in snippet view article find links to article

are being developed. The treatment is still a risky option due to the viral vector used which can cause ill-effects, for example giving rise to insertional

Sickle cell disease (14,974 words) [view diff] exact match in snippet view article find links to article

successfully treated in mice using gene therapy. The researchers used a viral vector to make the mice—which have essentially the same defect that causes human

Diabrotica speciosa (1,525 words) [view diff] exact match in snippet view article find links to article

observed distances has been found. There is evidence that D. speciosa is a viral vector for comoviruses, southern bean mosaic virus, mimosa mosaic virus, tymoviruses

Tablighi Jamaat (10,257 words) [view diff] exact match in snippet view article find links to article

Tablighi Jamaat event became India's worst coronavirus vector". "'Largest viral vector' — how Tablighi Jamaat spread coronavirus from Malaysia to India". ThePrint

Sleeping Beauty transposon system (2,762 words) [view diff] exact match in snippet view article find links to article

Hackett PB (April 2011). "The Sleeping Beauty transposon system: a non-viral vector for gene therapy". Human Molecular Genetics. 20 (R1): R14–R20. doi:10

Microbubble (3,928 words) [view diff] exact match in snippet view article find links to article

macrophages do not engulf these particles. Microbubbles also serve a non-viral vector for gene transfection through electrostatic bonds between a positively

Indiana University School of Medicine (9,265 words) [view diff] exact match in snippet view article find links to article

Clinical Cancer Center, and the only National Institute of Health-funded viral vector production facility for clinical grade therapeutics. The school is known

RNA silencing (5,449 words) [view diff] exact match in snippet view article find links to article

Species/formulation Packaging capacity Applications and considerations Viral vector Adenovirus Usually < 10 Kb dsDNA vector with large packaging capacity

George Church (geneticist) (6,751 words) [view diff] exact match in snippet view article

therapy with the new TLR9-edited Adeno-associated viruses (AAV) as a safer viral vector. Based on the research, Church and a postdoc from his lab who was also

Polyvalent influenza vaccine (2,231 words) [view diff] exact match in snippet view article find links to article

with a baculovirus as a viral vector, which infects invertebrates. To guide the rapid HA antigen expression, the viral vector help deliver the flu HA

Eocyte hypothesis (4,792 words) [view diff] exact match in snippet view article find links to article

into archaeal genomes. The transduction of genetic material through a viral vector led to an increase in complexity in the pre-eukaryotic cells. All these

Potato virus Y (5,658 words) [view diff] exact match in snippet view article find links to article

(Myzus persicae) has been found to be most effective in its role as viral vector, but others such as Aphis fabae, Aphis gossypii, Aphis nasturtii, Macrosiphum

Tetratricopeptide repeat protein 39B (1,318 words) [view diff] exact match in snippet view article find links to article

correlating with increased HDL-C. Knockdown of the mouse ortholog TTC39B via a viral vector (50% knockdown) resulted in significantly higher plasma HDL-C levels

Hippocampal replay (2,320 words) [view diff] exact match in snippet view article find links to article

previously injected bilaterally in the hippocampus with a recombinant viral vector containing an inhibitory designer receptor exclusively activated by a

Riccardo Cortese (2,836 words) [view diff] exact match in snippet view article find links to article

continued independent work in the further development and manufacture of viral vector-based therapeutics and vaccines. In 2015, Cortese founded a new company

Triatoma virus (2,490 words) [view diff] exact match in snippet view article find links to article

populations, and health concerns in humans, wild and domestic animals, viral vector controls are being investigated. Hesitations in early uses of Triatoma

Mavis Agbandje-McKenna (2,706 words) [view diff] exact match in snippet view article find links to article

to the patient's own immune system producing antibodies against the viral vector being used for treatment. Agbandje-McKenna and her colleagues at UF sought

Glossary of cellular and molecular biology (M–Z) (24,915 words) [view diff] exact match in snippet view article

transduction The transfer of genetic material between cells by a virus or viral vector, either naturally or artificially. transfectant A cell which has undergone

Science diplomacy and pandemics (9,809 words) [view diff] exact match in snippet view article find links to article

resulting in a variety of COVID-19 vaccines worldwide such as: DNA vaccine, viral vector vaccine, protein subunit vaccine, RNA vaccine, inactivated vaccine, and

Erythropoietin in neuroprotection (3,678 words) [view diff] exact match in snippet view article find links to article

inhibitor of wild type Epo from binding to its receptor. Though, the viral vector expressed R103-E Epo mutant was shown to be inhibitory to the progression

David T. Curiel (1,653 words) [view diff] exact match in snippet view article find links to article

blood vessels in mice without affecting healthy tissues. His use of viral vector technology to optimize the immune system's response to vaccines earned

Murine respirovirus (31,942 words) [view diff] exact match in snippet view article find links to article

2019-08-13. Charlesworth CT, Nakauchi H (November 2022). "An optimized Sendai viral vector platform for reprogramming to naive pluripotency". Cell Reports Methods

Moriya Tsuji (2,096 words) [view diff] exact match in snippet view article find links to article

field of malaria vaccine development, particularly the development of viral vector-based malaria vaccines that can elicit a potent protective CD8+ T-cell