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searching for Autophosphorylation 323 found (393 total)

alternate case: autophosphorylation

EEF2K (1,651 words) [view diff] exact match in snippet view article find links to article

activate the kinase domain, triggering rapid autophosphorylation of Thr-348. In the second step, autophosphorylation of Thr-348 leads to a conformational change
Elongation factor 2 kinase (893 words) [view diff] exact match in snippet view article find links to article
activate the kinase domain, triggering rapid autophosphorylation of Thr-348. In the second step, autophosphorylation of Thr-348 leads to a conformational change
TXK (gene) (718 words) [view diff] exact match in snippet view article
Suzuki N, Takeno M, et al. (2002). "Evidence of autophosphorylation in Txk: Y91 is an autophosphorylation site". Biol. Pharm. Bull. 25 (6): 718–21. doi:10
PTK6 (999 words) [view diff] exact match in snippet view article find links to article
epithelial tissues. The encoded protein has been shown to undergo autophosphorylation. Overexpression of this gene in mammary epithelial cells leads to
PLK4 (2,217 words) [view diff] exact match in snippet view article find links to article
which facilitates oligomerization, targeting, and promotes trans-autophosphorylation, limiting centriole duplication to once per cell cycle. Inhibitors
Megakaryocyte-associated tyrosine kinase (1,177 words) [view diff] exact match in snippet view article find links to article
lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal
CPS operon (219 words) [view diff] exact match in snippet view article find links to article
proteins. Reduced levels of membrane-derived oligosaccharides result in autophosphorylation of RcsC. This results in a phosphate group being transferred from
Tyrosine-protein kinase Yes (1,028 words) [view diff] exact match in snippet view article find links to article
S2CID 45071719. Toshima J, Ohashi K, Iwashita S, Mizuno K (1995). "Autophosphorylation activity and association with Src family kinase of Sky receptor tyrosine
DDR1 (1,207 words) [view diff] exact match in snippet view article find links to article
discoideum protein discoidin I in their extracellular domain. Its autophosphorylation is achieved by all collagens so far tested (type I to type VI). A
FER (gene) (968 words) [view diff] exact match in snippet view article
Priel-Halachmi S, et al. (2000). "N-terminal sequences direct the autophosphorylation states of the FER tyrosine kinases in vivo". Biochemistry. 39 (36):
RET proto-oncogene (2,385 words) [view diff] exact match in snippet view article find links to article
complex then brings together two molecules of RET, triggering trans-autophosphorylation of specific tyrosine residues within the tyrosine kinase domain of
Tyrosine-protein kinase CSK (977 words) [view diff] exact match in snippet view article find links to article
regulation of phagocytosis, dendrocyte differentiation, peptidyl-tyrosine autophosphorylation, platelet activation, positive regulation of MAP kinase activity
CAMK2B (1,157 words) [view diff] exact match in snippet view article find links to article
protein kinase II: identification of threonine-286 as the autophosphorylation site in the alpha subunit associated with the generation of Ca2+-independent
ATP13A2 (712 words) [view diff] exact match in snippet view article find links to article
response to manganese ion cellular iron ion homeostasis protein autophosphorylation cellular zinc ion homeostasis autophagosome organization regulation
ZAP70 (2,769 words) [view diff] exact match in snippet view article find links to article
ZAP-70 to phosphorylated T-cell receptor zeta and eta enhances its autophosphorylation and generates specific binding sites for SH2 domain-containing proteins"
DAPK2 (695 words) [view diff] exact match in snippet view article find links to article
PMID 10629061. Shani G, Henis-Korenblit S, Jona G, et al. (2001). "Autophosphorylation restrains the apoptotic activity of DRP-1 kinase by controlling dimerization
TTK (gene) (835 words) [view diff] exact match in snippet view article
Mattison CP, Old WM, Steiner E, et al. (2007). "Mps1 activation loop autophosphorylation enhances kinase activity". J. Biol. Chem. 282 (42): 30553–61. doi:10
Calcium/calmodulin-dependent protein kinase type II subunit alpha (1,466 words) [view diff] exact match in snippet view article find links to article
calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding
EPHB3 (933 words) [view diff] exact match in snippet view article find links to article
Rübsamen-Waigmann H, Strebhardt K (Jul 1998). "Tyrosine-614, the major autophosphorylation site of the receptor tyrosine kinase HEK2, functions as multi-docking
MAP3K11 (1,259 words) [view diff] exact match in snippet view article find links to article
activation loop is the key to mixed lineage kinase-3 activation via both autophosphorylation and hematopoietic progenitor kinase 1 phosphorylation". J. Biol.
Protein kinase (1,635 words) [view diff] exact match in snippet view article find links to article
extracellular signal. Trans-autophosphorylation (phosphorylation by the other kinase in the dimer) of the kinase. Autophosphorylation stabilizes the active
Ste5 (702 words) [view diff] exact match in snippet view article find links to article
is also involved in down regulating of signalling. It stimulates autophosphorylation of Fus3, which results in phosphorylation of Ste5, causing a downregulation
Vascular endothelial growth factor A (3,053 words) [view diff] exact match in snippet view article find links to article
within the molecule in a process called auto-phosphorylation. The autophosphorylation of these amino acids allows for signalling molecules within to the
Tyrosine-protein kinase Fes/Fps (577 words) [view diff] exact match in snippet view article find links to article
polymerization peptidyl-tyrosine autophosphorylation regulation of cell differentiation protein autophosphorylation peptidyl-tyrosine phosphorylation
Tyrosin-protein kinase Lck (4,466 words) [view diff] exact match in snippet view article find links to article
coreceptor-free LCK via its cytoplasmic domain, promoting the LCK autophosphorylation. There is very little understanding of the role of CD45 isoforms
Tyrosine-protein kinase SYK (2,083 words) [view diff] exact match in snippet view article find links to article
positive regulation of peptidyl-tyrosine phosphorylation protein autophosphorylation leukotriene biosynthetic process viral process positive regulation
TYRO3 (962 words) [view diff] exact match in snippet view article find links to article
PMID 7511603. Toshima J, Ohashi K, Iwashita S, Mizuno K (1995). "Autophosphorylation activity and association with Src family kinase of Sky receptor tyrosine
KaiA (3,108 words) [view diff] exact match in snippet view article find links to article
is a timing input device that controls KaiA stimulation of KaiC autophosphorylation, thus crucial for circadian oscillation. There appear to be long
Janus kinase 3 (5,166 words) [view diff] exact match in snippet view article find links to article
using Jak3-wt or villin/gelsolin-wt as substrate showed that Jak3 autophosphorylation was the rate-limiting step during interactions between Jak3 and cytoskeletal
FGR (gene) (1,235 words) [view diff] exact match in snippet view article
of cell shape peptidyl-tyrosine autophosphorylation integrin-mediated signaling pathway protein autophosphorylation positive regulation of phosphatidylinositol
Janus kinase 3 (5,166 words) [view diff] exact match in snippet view article find links to article
using Jak3-wt or villin/gelsolin-wt as substrate showed that Jak3 autophosphorylation was the rate-limiting step during interactions between Jak3 and cytoskeletal
DNAJC3 (1,254 words) [view diff] exact match in snippet view article find links to article
double-stranded RNA-dependent protein kinase, PKR, to regulate its autophosphorylation and activity". The Journal of Biological Chemistry. 271 (3): 1702–7
DAPK1 (1,172 words) [view diff] exact match in snippet view article find links to article
death-associated protein kinase is controlled by a unique inhibitory autophosphorylation-based mechanism". The Journal of Biological Chemistry. 276 (50):
ERN1 (2,089 words) [view diff] exact match in snippet view article find links to article
possesses two functional enzymatic domains, an endonuclease and a trans-autophosphorylation kinase domain. Upon activation, IRE1α oligomerizes and carries out
IRAK4 (2,536 words) [view diff] exact match in snippet view article find links to article
in a decrease in the kinase activity of IRAK4. A structure of the autophosphorylation of the activation loop has been determined in which the activation
Fus3 (742 words) [view diff] exact match in snippet view article find links to article
locates to the nucleus. One regulator of Fus3 is Ste5. Ste5 causes autophosphorylation of one of two locations modulated by the MAPK kinase Ste7 (the main
Epidermal growth factor receptor (6,879 words) [view diff] exact match in snippet view article find links to article
intrinsic intracellular protein-tyrosine kinase activity. As a result, autophosphorylation of several tyrosine (Y) residues in the C-terminal domain of EGFR
Non-receptor tyrosine kinase (2,717 words) [view diff] exact match in snippet view article find links to article
enzymatic activity. Activation loop phosphorylation occurs via trans-autophosphorylation or phosphorylation by different nRTKs. It is possible to negatively
Protein kinase R (4,412 words) [view diff] exact match in snippet view article find links to article
May ER, Cole JL (July 2019). "Structural Basis of Protein Kinase R Autophosphorylation". Biochemistry. 58 (27): 2967–2977. doi:10.1021/acs.biochem.9b00161
Proto-oncogene tyrosine-protein kinase Src (2,648 words) [view diff] exact match in snippet view article find links to article
resulting in the opening up of the SH3, SH2 and kinase domains and the autophosphorylation of the residue tyrosine 416. c-Src can be activated by many transmembrane
ERBB3 (2,816 words) [view diff] exact match in snippet view article find links to article
activated through autophosphorylation upon ligand binding, ErbB3 was found to be kinase impaired, having only 1/1000 the autophosphorylation activity of EGFR
CLK2 (948 words) [view diff] exact match in snippet view article find links to article
PDBe-KB. Lee K, Du C, Horn M, Rabinow L (Nov 1996). "Activity and autophosphorylation of LAMMER protein kinases". The Journal of Biological Chemistry.
Integrated stress response (1,625 words) [view diff] exact match in snippet view article find links to article
from the luminal domain. This causes PERK to dimerize, leading to autophosphorylation and activation. The activated PERK kinase will then phosphorylate
GRK5 (1,986 words) [view diff] exact match in snippet view article find links to article
P, Gurevich VV, Benovic JL (Apr 1994). "Phospholipid-stimulated autophosphorylation activates the G protein-coupled receptor kinase GRK5". The Journal
Kinase insert domain receptor (794 words) [view diff] exact match in snippet view article find links to article
regulation of ERK1 and ERK2 cascade peptidyl-tyrosine autophosphorylation protein autophosphorylation positive regulation of focal adhesion assembly positive
ERBB4 (1,597 words) [view diff] exact match in snippet view article find links to article
positive regulation of protein localization to cell surface protein autophosphorylation cardiac muscle tissue regeneration positive regulation of phosphatidylinositol
PTK2B (1,887 words) [view diff] exact match in snippet view article find links to article
positive regulation of peptidyl-tyrosine phosphorylation protein autophosphorylation innate immune response negative regulation of myeloid cell differentiation
STYK1 (476 words) [view diff] exact match in snippet view article find links to article
membrane plasma membrane membrane Biological process peptidyl-tyrosine autophosphorylation cell differentiation protein phosphorylation innate immune response
EPH receptor A4 (766 words) [view diff] exact match in snippet view article find links to article
PMID 8125298. Ellis C, Kasmi F, Ganju P, et al. (1996). "A juxtamembrane autophosphorylation site in the Eph family receptor tyrosine kinase, Sek, mediates high
Bruton's tyrosine kinase (2,841 words) [view diff] exact match in snippet view article find links to article
development intracellular signal transduction peptidyl-tyrosine autophosphorylation B cell activation positive regulation of NF-kappaB transcription
TSSK2 (414 words) [view diff] exact match in snippet view article find links to article
development protein phosphorylation spermatogenesis spermatid development protein autophosphorylation peptidyl-serine phosphorylation Sources:Amigo / QuickGO
MAP3K9 (462 words) [view diff] exact match in snippet view article find links to article
DNA-templated protein phosphorylation positive regulation of apoptotic process protein autophosphorylation apoptotic process MAPK cascade Sources:Amigo / QuickGO
LYN (3,807 words) [view diff] exact match in snippet view article find links to article
turn, activation of the insulin receptor has been shown to increase autophosphorylation of Lyn suggesting a possible feedback loop. The insulin secretagogue
MAP3K13 (451 words) [view diff] exact match in snippet view article find links to article
process phosphorylation JNK cascade protein phosphorylation protein autophosphorylation positive regulation of NF-kappaB transcription factor activity MAPK
SIK1 (397 words) [view diff] exact match in snippet view article find links to article
of mitotic cell cycle regulation of cell differentiation protein autophosphorylation cell cycle positive regulation of anoikis entrainment of circadian
Janus kinase 1 (2,423 words) [view diff] exact match in snippet view article find links to article
interleukin-2-mediated signaling pathway peptidyl-tyrosine autophosphorylation protein autophosphorylation cell migration innate immune response interleukin-12-mediated
CDK12 (514 words) [view diff] exact match in snippet view article find links to article
phosphorylation regulation of RNA splicing RNA splicing protein autophosphorylation regulation of MAP kinase activity transcription elongation from RNA
Pedunculagin (519 words) [view diff] exact match in snippet view article find links to article
"Further characterization of galloyl pedunculagin as an effective autophosphorylation inhibitor of C-kinase in vitro". Biological & Pharmaceutical Bulletin
TAOK2 (953 words) [view diff] exact match in snippet view article find links to article
protein autophosphorylation activation of protein kinase activity regulation of actin cytoskeleton organization protein autophosphorylation basal dendrite
Janus kinase (974 words) [view diff] exact match in snippet view article find links to article
bringing the two JAKs close enough to phosphorylate each other. The JAK autophosphorylation induces a conformational change within itself, enabling it to transduce
Potato carboxypeptidase inhibitor (605 words) [view diff] exact match in snippet view article find links to article
action is inhibition of receptor dimerization and receptor trans-autophosphorylation induced by epidermal growth factor (EGF). PCI blocks the formation
KSR1 (553 words) [view diff] exact match in snippet view article find links to article
(2011). "KSR1 is a functional protein kinase capable of serine autophosphorylation and direct phosphorylation of MEK1". Exp. Cell Res. 317 (4): 452–63
HCK (2,331 words) [view diff] exact match in snippet view article find links to article
assembly peptidyl-tyrosine autophosphorylation phagocytosis integrin-mediated signaling pathway protein autophosphorylation peptidyl-tyrosine phosphorylation
TESK1 (740 words) [view diff] exact match in snippet view article find links to article
activity of testis-specific protein kinase 1 and its regulation by autophosphorylation of serine-215 within the activation loop". J. Biol. Chem. 274 (17):
STK38 (706 words) [view diff] exact match in snippet view article find links to article
"Mechanism of Ca2+-mediated regulation of NDR protein kinase through autophosphorylation and phosphorylation by an upstream kinase". J. Biol. Chem. 278 (9):
SNF1LK2 (676 words) [view diff] exact match in snippet view article find links to article
nucleotide-activated protein kinase complex Biological process protein autophosphorylation protein phosphorylation intracellular signal transduction phosphorylation
CHEK2 (2,797 words) [view diff] exact match in snippet view article find links to article
form the dimer. After the protein dimerizes the KD is activated via autophosphorylation. Once the KD is activated the CHK2 dimer dissociates. The CHEK2 gene
PAK2 (2,256 words) [view diff] exact match in snippet view article find links to article
1995). "A novel serine kinase activated by rac1/CDC42Hs-dependent autophosphorylation is related to PAK65 and STE20". The EMBO Journal. 14 (9): 1970–8
EIF2AK4 (501 words) [view diff] exact match in snippet view article find links to article
endoplasmic reticulum stress induction by virus of host autophagy protein autophosphorylation cell cycle negative regulation by host of viral genome replication
TAB1 (2,197 words) [view diff] exact match in snippet view article find links to article
"MAPKK-independent activation of p38alpha mediated by TAB1-dependent autophosphorylation of p38alpha". Science. 295 (5558): 1291–4. Bibcode:2002Sci...295
Receptor tyrosine kinase (3,078 words) [view diff] exact match in snippet view article find links to article
the kinase activity of these receptors, which catalyses receptor autophosphorylation and tyrosine phosphorylation of RTK substrates. A kinase is a type
INSRR (657 words) [view diff] exact match in snippet view article find links to article
axon Biological process actin cytoskeleton reorganization protein autophosphorylation protein phosphorylation cellular response to alkaline pH male sex
DYRK1B (894 words) [view diff] exact match in snippet view article find links to article
phosphorylation peptidyl-tyrosine phosphorylation myoblast fusion adipose tissue development phosphorylation protein autophosphorylation Sources:Amigo / QuickGO
MAPKAPK5 (756 words) [view diff] exact match in snippet view article find links to article
phosphorylation positive regulation of telomerase activity protein autophosphorylation Ras protein signal transduction regulation of translation signal
Tropomyosin receptor kinase C (3,901 words) [view diff] exact match in snippet view article find links to article
ligand binding induces receptor dimerization followed by trans-autophosphorylation on conserved tyrosine in the intracellular (cytoplasmic) domain of
MKNK2 (834 words) [view diff] exact match in snippet view article find links to article
extrinsic apoptotic signaling pathway in absence of ligand protein autophosphorylation regulation of translation apoptotic process hemopoiesis Sources:Amigo
PASK (796 words) [view diff] exact match in snippet view article find links to article
Biological process regulation of respiratory gaseous exchange protein autophosphorylation negative regulation of glycogen biosynthetic process positive regulation
Janus kinase 2 (3,166 words) [view diff] exact match in snippet view article find links to article
peptidyl-tyrosine phosphorylation erythrocyte differentiation protein autophosphorylation platelet-derived growth factor receptor signaling pathway positive
MAPKAPK5 (756 words) [view diff] exact match in snippet view article find links to article
phosphorylation positive regulation of telomerase activity protein autophosphorylation Ras protein signal transduction regulation of translation signal
FYN (4,778 words) [view diff] exact match in snippet view article find links to article
ZAP-70 to phosphorylated T-cell receptor zeta and eta enhances its autophosphorylation and generates specific binding sites for SH2 domain-containing proteins"
Ectonucleotide pyrophosphatase/phosphodiesterase 1 (1,444 words) [view diff] exact match in snippet view article find links to article
PMID 2211644. Belli SI, Mercuri FA, Sali A, Goding JW (1995). "Autophosphorylation of PC-1 (alkaline phosphodiesterase I/nucleotide pyrophosphatase)
Myosin-IIIa (637 words) [view diff] exact match in snippet view article find links to article
phosphorylation response to stimulus protein phosphorylation protein autophosphorylation visual perception hearing cochlea morphogenesis Sources:Amigo / QuickGO
PDGFB (434 words) [view diff] exact match in snippet view article find links to article
multicellular organism development positive regulation of protein autophosphorylation positive regulation of reactive oxygen species metabolic process
STK10 (595 words) [view diff] exact match in snippet view article find links to article
aggregation phosphorylation regulation of lymphocyte migration protein autophosphorylation cell cycle protein phosphorylation neutrophil degranulation regulation
Fyn-related kinase (575 words) [view diff] exact match in snippet view article find links to article
transcription by RNA polymerase II protein phosphorylation peptidyl-tyrosine autophosphorylation innate immune response negative regulation of cell population proliferation
Timothy syndrome (1,234 words) [view diff] exact match in snippet view article find links to article
impulse propagation. Single cell studies identified that CaMKII autophosphorylation reduced the peak sodium current, thus causing the slowing of conduction
Integrin-linked kinase (2,654 words) [view diff] exact match in snippet view article find links to article
direct phosphorylation target of CML9. With the addition of CML9, autophosphorylation of ILK1 is diminished, the present irrespective of calcium available
CD79B (987 words) [view diff] exact match in snippet view article find links to article
alpha/Ig beta immunoreceptor tyrosine activation motif binding and autophosphorylation". J. Biol. Chem. 270 (19): 11590–4. doi:10.1074/jbc.270.19.11590
MAP3K12 (1,255 words) [view diff] exact match in snippet view article find links to article
phosphorylation JNK cascade peptidyl-serine phosphorylation protein autophosphorylation peptidyl-threonine phosphorylation negative regulation of motor neuron
TRPM7 (548 words) [view diff] exact match in snippet view article find links to article
protein phosphorylation calcium ion transmembrane transport protein autophosphorylation necroptosis calcium ion transport transmembrane transport Sources:Amigo
Tyrosine-protein kinase BLK (847 words) [view diff] exact match in snippet view article find links to article
phosphorylation regulation of cell population proliferation peptidyl-tyrosine autophosphorylation innate immune response positive regulation of insulin secretion cell
Zalutumumab (528 words) [view diff] exact match in snippet view article find links to article
epidermal growth factor or TGF alpha, dimerization occurs, leading to autophosphorylation on the intracellular tyrosine residues. Following phosphorylation
MAPK15 (1,095 words) [view diff] exact match in snippet view article find links to article
positive regulation of telomerase activity MAPK cascade protein autophosphorylation regulation of gene expression regulation of autophagy protein localization
MYLK2 (777 words) [view diff] exact match in snippet view article find links to article
of gene expression skeletal muscle cell differentiation protein autophosphorylation peptidyl-threonine phosphorylation striated muscle contraction peptidyl-serine
VEGFR1 (1,086 words) [view diff] exact match in snippet view article find links to article
receptor signaling pathway embryonic morphogenesis angiogenesis protein autophosphorylation positive regulation of phosphatidylinositol 3-kinase signaling peptidyl-tyrosine
PLK3 (1,212 words) [view diff] exact match in snippet view article find links to article
(2002). "Phosphorylation of threonine 68 promotes oligomerization and autophosphorylation of the Chk2 protein kinase via the forkhead-associated domain". J
LMTK2 (813 words) [view diff] exact match in snippet view article find links to article
recycling peptidyl-serine phosphorylation endocytic recycling protein autophosphorylation peptidyl-threonine phosphorylation negative regulation of phosphoprotein
Mary B. Kennedy (1,223 words) [view diff] exact match in snippet view article find links to article
major constituent of the postsynaptic density, and is regulated by autophosphorylation following activation by synaptic activity. Her lab later used micro-sequencing
EIF2S1 (1,448 words) [view diff] exact match in snippet view article find links to article
stress transmembrane transport translational initiation protein autophosphorylation regulation of translation regulation of translational initiation
PIAS1 (1,351 words) [view diff] exact match in snippet view article find links to article
"PIAS1-mediated sumoylation of focal adhesion kinase activates its autophosphorylation". J. Biol. Chem. 278 (48): 47434–47440. doi:10.1074/jbc.M308562200
PAK1 (5,202 words) [view diff] exact match in snippet view article find links to article
this autoinhibition and initiate conformational rearrangements and autophosphorylation events leading to kinase activation. IPA-3 (1,1′-disulfanediyldinaphthalen-2-ol)
MARK3 (1,217 words) [view diff] exact match in snippet view article find links to article
phosphorylation positive regulation of protein binding intracellular signal transduction peptidyl-serine autophosphorylation Sources:Amigo / QuickGO
AKT3 (1,189 words) [view diff] exact match in snippet view article find links to article
"Identification of serine 643 of protein kinase C-delta as an important autophosphorylation site for its enzymatic activity". J. Biol. Chem. 272 (39): 24550–5
PRKD2 (940 words) [view diff] exact match in snippet view article find links to article
vascular endothelial growth factor receptor signaling pathway protein autophosphorylation cellular response to vascular endothelial growth factor stimulus
MAPK11 (1,233 words) [view diff] exact match in snippet view article find links to article
"MAPKK-independent activation of p38alpha mediated by TAB1-dependent autophosphorylation of p38alpha". Science. 295 (5558): 1291–4. Bibcode:2002Sci...295
MKNK1 (1,031 words) [view diff] exact match in snippet view article find links to article
signal transduction phosphorylation protein phosphorylation protein autophosphorylation regulation of translation peptidyl-serine phosphorylation Sources:Amigo
PRKCG (526 words) [view diff] exact match in snippet view article find links to article
rhythm peptidyl-serine phosphorylation learning or memory protein autophosphorylation negative regulation of proteasomal protein catabolic process regulation
ABL (gene) (3,502 words) [view diff] exact match in snippet view article
binding cell adhesion regulation of autophagy peptidyl-tyrosine autophosphorylation alpha-beta T cell differentiation regulation of cellular senescence
MAP3K10 (1,089 words) [view diff] exact match in snippet view article find links to article
phosphorylation JNK cascade peptidyl-serine phosphorylation protein autophosphorylation smoothened signaling pathway peptidyl-threonine phosphorylation negative
MAP2K2 (1,231 words) [view diff] exact match in snippet view article find links to article
regulation of early endosome to late endosome transport peptidyl-serine autophosphorylation negative regulation of gene expression positive regulation of protein
Protein kinase D1 (1,304 words) [view diff] exact match in snippet view article find links to article
kinase/NF-kappaB signaling integrin-mediated signaling pathway protein autophosphorylation cellular response to oxidative stress cellular response to vascular
MOS (gene) (669 words) [view diff] exact match in snippet view article
Cellular component cytoplasm cytosol Biological process protein autophosphorylation establishment of meiotic spindle orientation chromatin organization
PDGFD (793 words) [view diff] exact match in snippet view article find links to article
regulation of monocyte extravasation positive regulation of protein autophosphorylation positive regulation of cell population proliferation positive regulation
MARK2 (1,143 words) [view diff] exact match in snippet view article find links to article
polarity positive regulation of neuron projection development protein autophosphorylation peptidyl-threonine phosphorylation activation of protein kinase activity
CAMKK2 (1,817 words) [view diff] exact match in snippet view article find links to article
determined. The identified isoforms exhibit a distinct ability to undergo autophosphorylation and to phosphorylate the downstream kinases. GRCh38: Ensembl release
GFRA2 (gene) (812 words) [view diff] exact match in snippet view article
guidance positive regulation of peptidyl-serine phosphorylation of STAT protein negative regulation of protein autophosphorylation Sources:Amigo / QuickGO
CAMK4 (1,126 words) [view diff] exact match in snippet view article find links to article
differentiation long-term memory peptidyl-serine phosphorylation protein autophosphorylation inflammatory response signal transduction Sources:Amigo / QuickGO
CAMK2D (872 words) [view diff] exact match in snippet view article find links to article
phosphorylation endoplasmic reticulum calcium ion homeostasis protein autophosphorylation relaxation of cardiac muscle cardiac muscle cell contraction regulation
CAMK2G (1,113 words) [view diff] exact match in snippet view article find links to article
oligomerization regulation of cellular response to heat protein autophosphorylation regulation of skeletal muscle adaptation calcium ion transport protein
MERTK (1,093 words) [view diff] exact match in snippet view article find links to article
Templeton D, Kung HJ (August 1996). "Identification of the major autophosphorylation sites of Nyk/Mer, an NCAM-related receptor tyrosine kinase". The
MELK (977 words) [view diff] exact match in snippet view article find links to article
cell proliferation positive regulation of apoptotic process protein autophosphorylation cell cycle cell population proliferation apoptotic process peptidyl-tyrosine
BCR (gene) (1,541 words) [view diff] exact match in snippet view article
regulation of neutrophil degranulation inner ear morphogenesis protein autophosphorylation platelet-derived growth factor receptor signaling pathway regulation
Ephrin receptor (3,454 words) [view diff] exact match in snippet view article find links to article
repress downstream signaling cascades. The structure of the trans-autophosphorylation of the juxtamembrane region of EPHA2 has been observed within a crystal
Marina Picciotto (1,388 words) [view diff] exact match in snippet view article find links to article
"Calcium/calmodulin-dependent protein kinase I - cDNA cloning and identification of autophosphorylation site". J. Biol. Chem. 268 (35): 26512–26521. doi:10.1016/S0021-9258(19)74343-9
PDGFRB (3,403 words) [view diff] exact match in snippet view article find links to article
Wernstedt C, Claesson-Welsh L, Heldin CH (October 1994). "A unique autophosphorylation site in the platelet-derived growth factor alpha receptor from a
MAPKAPK3 (1,042 words) [view diff] exact match in snippet view article find links to article
pathway macropinocytosis peptidyl-serine phosphorylation protein autophosphorylation signal transduction toll-like receptor signaling pathway MAPK cascade
Cyclin-dependent kinase 9 (1,460 words) [view diff] exact match in snippet view article find links to article
EM, Meisenhelder J, Thompson NE, Jones KA (September 2000). "CDK9 autophosphorylation regulates high-affinity binding of the human immunodeficiency virus
FLT4 (1,183 words) [view diff] exact match in snippet view article find links to article
proliferation positive regulation of ERK1 and ERK2 cascade protein autophosphorylation positive regulation of vascular endothelial growth factor production
Ataxia telangiectasia and Rad3 related (3,429 words) [view diff] exact match in snippet view article find links to article
(January 2003). "DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation". Nature. 421 (6922): 499–506. Bibcode:2003Natur
MAP3K2 (1,505 words) [view diff] exact match in snippet view article find links to article
MEKK2 is activated through homodimerization and subsequent trans-autophosphorylation at MEKK2-S519. MEKK2 is regulated by 14-3-3 proteins which bind to
MAPK3 (1,140 words) [view diff] exact match in snippet view article find links to article
activity positive regulation of telomerase activity peptidyl-tyrosine autophosphorylation sensory perception of pain positive regulation of cyclase activity
EIF2AK3 (1,365 words) [view diff] exact match in snippet view article find links to article
phosphorylation in response to endoplasmic reticulum stress protein autophosphorylation positive regulation of vascular endothelial growth factor production
EPH receptor A1 (622 words) [view diff] exact match in snippet view article find links to article
angiogenesis positive regulation of cell population proliferation protein autophosphorylation peptidyl-tyrosine phosphorylation substrate adhesion-dependent cell
KdpD/KdpE two-component system (1,806 words) [view diff] exact match in snippet view article find links to article
potassium affects the autophosphorylation of KdpD. High concentrations of intracellular potassium inhibit the autophosphorylation of KdpD. KdpD also detects
PTK2 (4,724 words) [view diff] exact match in snippet view article find links to article
phosphorylation epidermal growth factor receptor signaling pathway protein autophosphorylation nuclear migration negative regulation of autophagy positive regulation
TEK tyrosine kinase (1,695 words) [view diff] exact match in snippet view article find links to article
ERK1 and ERK2 cascade negative regulation of angiogenesis protein autophosphorylation positive regulation of focal adhesion assembly regulation of establishment
Signal transduction (7,609 words) [view diff] exact match in snippet view article find links to article
The interaction between the cytoplasmic domains stimulates the autophosphorylation of tyrosine residues within the intracellular kinase domains of the
Sporulation in Bacillus subtilis (734 words) [view diff] exact match in snippet view article find links to article
phosphate to the Spo0F Sda Blocks autophosphorylation of KinA KinB Transfers phosphate to the Spo0F KipI Blocks autophosphorylation of KinA Spo0A Activates several
CAD protein (1,156 words) [view diff] exact match in snippet view article find links to article
biosynthetic process pyrimidine nucleotide biosynthetic process protein autophosphorylation metabolism peptidyl-threonine phosphorylation 'de novo' UMP biosynthetic
ACVR1B (1,542 words) [view diff] exact match in snippet view article find links to article
of signal transduction negative regulation of cell growth protein autophosphorylation peptidyl-threonine phosphorylation signal transduction positive regulation
MAP3K3 (1,820 words) [view diff] exact match in snippet view article find links to article
protein phosphorylation positive regulation of p38MAPK cascade protein autophosphorylation blood vessel development phosphorylation positive regulation of I-kappaB
ITK (gene) (1,522 words) [view diff] exact match in snippet view article
response regulation of cell population proliferation peptidyl-tyrosine autophosphorylation T cell receptor signaling pathway T cell activation signal transduction
TRIM24 (1,289 words) [view diff] exact match in snippet view article find links to article
expression protein catabolic process protein ubiquitination protein autophosphorylation negative regulation of transcription, DNA-templated negative regulation
PDGFA (1,108 words) [view diff] exact match in snippet view article find links to article
biosynthetic process angiogenesis positive regulation of protein autophosphorylation positive regulation of ERK1 and ERK2 cascade regulation of smooth
Nucleoside-diphosphate kinase (2,538 words) [view diff] exact match in snippet view article find links to article
kinase in plants are analogous to activities described in humans as autophosphorylation activity takes place from ATP and GTP. In addition to this, plants
PTPRF (1,451 words) [view diff] exact match in snippet view article find links to article
CA, Dixon JE (1996). "Oncogenic RET receptors display different autophosphorylation sites and substrate binding specificities". J. Biol. Chem. 271 (10):
EnvZ/OmpR two-component system (928 words) [view diff] exact match in snippet view article find links to article
follows: Activation of the inner membrane sensor histidine kinase EnvZ, Autophosphorylation of EnvZ at His243, Phosphate transfer to OmpR at Asp 55, Binding
MEX3B (459 words) [view diff] exact match in snippet view article find links to article
component cytoplasm P-body nucleus nucleoplasm cytosol Biological process protein autophosphorylation protein phosphorylation Sources:Amigo / QuickGO
Caveolin 1 (1,555 words) [view diff] exact match in snippet view article find links to article
contraction vesicle organization negative regulation of peptidyl-tyrosine autophosphorylation regulation of cardiac muscle cell action potential involved in regulation
Cyclin E1 (1,720 words) [view diff] exact match in snippet view article find links to article
(1996). "Activation of cyclin E/CDK2 is coupled to site-specific autophosphorylation and ubiquitin-dependent degradation of cyclin E." EMBO J. 15 (16):
CD79A (2,434 words) [view diff] exact match in snippet view article find links to article
Sada K, Yamamura H, Cambier JC (December 1995). "Role of the Syk autophosphorylation site and SH2 domains in B cell antigen receptor signaling". The Journal
Neratinib (1,300 words) [view diff] exact match in snippet view article find links to article
and 1.4 μM, respectively. In BT474 cells, neratinib reduces HER2 autophosphorylation, and inhibited cyclin D1 expression while reduced proliferation has
EPHA8 (783 words) [view diff] exact match in snippet view article find links to article
peptidyl-tyrosine phosphorylation substrate-dependent cell migration protein autophosphorylation axon guidance neuron projection development regulation of cell adhesion
Platelet-derived growth factor receptor A (3,354 words) [view diff] exact match in snippet view article find links to article
Wernstedt C, Claesson-Welsh L, Heldin CH (October 1994). "A unique autophosphorylation site in the platelet-derived growth factor alpha receptor from a
PDGFC (1,369 words) [view diff] exact match in snippet view article find links to article
population proliferation bone development positive regulation of protein autophosphorylation positive regulation of phosphatidylinositol 3-kinase signaling multicellular
Platycarya strobilacea (202 words) [view diff] exact match in snippet view article find links to article
"Further characterization of galloyl pedunculagin as an effective autophosphorylation inhibitor of C-kinase in vitro". Biological & Pharmaceutical Bulletin
STK25 (665 words) [view diff] exact match in snippet view article find links to article
cell polarity protein phosphorylation Golgi localization protein autophosphorylation response to hydrogen peroxide signal transduction positive regulation
ABL2 (1,464 words) [view diff] exact match in snippet view article find links to article
positive regulation of neuron projection development peptidyl-tyrosine autophosphorylation peptidyl-tyrosine phosphorylation innate immune response signal transduction
Histidine kinase (2,112 words) [view diff] exact match in snippet view article find links to article
motifs. These motifs include the H, N, G1, F, and G2 boxes. The autophosphorylation H-box is contained in the N-terminal dimerization and histidine phosphotransfer
MAPKAPK2 (1,726 words) [view diff] exact match in snippet view article find links to article
vascular endothelial growth factor stimulus mRNA stabilization protein autophosphorylation 3'-UTR-mediated mRNA stabilization cellular response to DNA damage
Platelet-derived growth factor receptor (1,563 words) [view diff] exact match in snippet view article find links to article
PMID 18392794. S2CID 21872247. Kazlauskas A, Cooper JA (September 1989). "Autophosphorylation of the PDGF receptor in the kinase insert region regulates interactions
IRAK3 (708 words) [view diff] exact match in snippet view article find links to article
transduction negative regulation of macrophage cytokine production protein autophosphorylation negative regulation of protein-containing complex disassembly response
EPHA7 (711 words) [view diff] exact match in snippet view article find links to article
positive regulation of protein phosphorylation regulation of protein autophosphorylation phosphorylation transmembrane receptor protein tyrosine kinase signaling
Fibroblast growth factor receptor 4 (1,291 words) [view diff] exact match in snippet view article find links to article
ERK1 and ERK2 cascade positive regulation of proteolysis protein autophosphorylation peptidyl-tyrosine phosphorylation cell migration phosphatidylinositol
IRAK3 (708 words) [view diff] exact match in snippet view article find links to article
transduction negative regulation of macrophage cytokine production protein autophosphorylation negative regulation of protein-containing complex disassembly response
Major vault protein (1,419 words) [view diff] exact match in snippet view article find links to article
pathway negative regulation of signaling negative regulation of protein autophosphorylation neutrophil degranulation transport Sources:Amigo / QuickGO
MAP4K1 (559 words) [view diff] exact match in snippet view article find links to article
membrane intracellular anatomical structure Biological process protein autophosphorylation protein phosphorylation response to stress cell population proliferation
CD135 (1,727 words) [view diff] exact match in snippet view article find links to article
of cell population proliferation lymphocyte proliferation protein autophosphorylation positive regulation of phosphatidylinositol 3-kinase signaling peptidyl-tyrosine
EPH receptor B4 (731 words) [view diff] exact match in snippet view article find links to article
development protein phosphorylation cell adhesion angiogenesis protein autophosphorylation peptidyl-tyrosine phosphorylation ephrin receptor signaling pathway
PRKRIR (611 words) [view diff] exact match in snippet view article find links to article
double-stranded RNA-dependent protein kinase, PKR, to regulate its autophosphorylation and activity". J. Biol. Chem. 271 (3): 1702–7. doi:10.1074/jbc.271
PRKACA (1,681 words) [view diff] exact match in snippet view article find links to article
formation neural tube closure peptidyl-threonine phosphorylation protein autophosphorylation positive regulation of protein export from nucleus sperm capacitation
TNK2 (1,756 words) [view diff] exact match in snippet view article find links to article
regulation of peptidyl-tyrosine phosphorylation peptidyl-tyrosine autophosphorylation regulation of clathrin-dependent endocytosis innate immune response
Fibroblast growth factor receptor 3 (1,845 words) [view diff] exact match in snippet view article find links to article
proliferation positive regulation of ERK1 and ERK2 cascade protein autophosphorylation peptidyl-tyrosine phosphorylation endochondral bone growth positive
TGF alpha (2,112 words) [view diff] exact match in snippet view article find links to article
protein-tyrosine kinase. The activity of protein-tyrosine kinase causes an autophosphorylation to occur among several tyrosine residues within EGFR, influencing
EPH receptor B1 (1,109 words) [view diff] exact match in snippet view article find links to article
regulation of neuron death regulation of ERK1 and ERK2 cascade protein autophosphorylation peptidyl-tyrosine phosphorylation immunological synapse formation
MOBKL1A (383 words) [view diff] exact match in snippet view article find links to article
nucleus nucleolus cytosol Biological process regulation of protein autophosphorylation hippo signaling positive regulation of phosphorylation positive regulation
WNK4 (3,448 words) [view diff] exact match in snippet view article find links to article
EJ (May 2014). "Chloride sensing by WNK1 involves inhibition of autophosphorylation". Science Signaling. 7 (324): ra41. doi:10.1126/scisignal.2005050
TNKS1BP1 (663 words) [view diff] exact match in snippet view article find links to article
peptidyl-threonine phosphorylation positive regulation of protein autophosphorylation positive regulation of peptidyl-serine phosphorylation cellular response
MDC1 (3,123 words) [view diff] exact match in snippet view article find links to article
Minter-Dykhouse K, Chen DJ, Chen J (Nov 2004). "MDC1 regulates DNA-PK autophosphorylation in response to DNA damage". J Biol Chem. 279 (45): 46359–62. doi:10
Cyclin-dependent kinase 7 (2,347 words) [view diff] exact match in snippet view article find links to article
EM, Meisenhelder J, Thompson NE, Jones KA (September 2000). "CDK9 autophosphorylation regulates high-affinity binding of the human immunodeficiency virus
Tyrosine kinase 2 (2,850 words) [view diff] exact match in snippet view article find links to article
proliferation type I interferon signaling pathway peptidyl-tyrosine autophosphorylation innate immune response cell migration interleukin-12-mediated signaling
TOM1L1 (589 words) [view diff] exact match in snippet view article find links to article
regulation of mitotic nuclear division positive regulation of protein autophosphorylation protein transport ubiquitin-dependent protein catabolic process via
SLA2 (430 words) [view diff] exact match in snippet view article find links to article
signaling pathway cell migration cell differentiation peptidyl-tyrosine autophosphorylation regulation of cell population proliferation innate immune response
TAOK1 (753 words) [view diff] exact match in snippet view article find links to article
kinase activity regulation of actin cytoskeleton organization protein autophosphorylation neuron cellular homeostasis regulation of microtubule cytoskeleton
STK11 (2,831 words) [view diff] exact match in snippet view article find links to article
intrinsic apoptotic signaling pathway by p53 class mediator protein autophosphorylation cell cycle negative regulation of epithelial cell proliferation involved
Endoglin (2,843 words) [view diff] exact match in snippet view article find links to article
of nitric-oxide synthase activity negative regulation of protein autophosphorylation venous blood vessel morphogenesis cell motility positive regulation
Protein kinase A (2,665 words) [view diff] exact match in snippet view article find links to article
series of phosphorylation events, which can include modification by autophosphorylation and phosphorylation by regulatory kinases, such as PDK1. Thus, PKA
MINK1 (665 words) [view diff] exact match in snippet view article find links to article
phosphorylation JNK cascade regulation of cell-cell adhesion protein autophosphorylation chemical synaptic transmission regulation of mitotic cell cycle regulation
Adiponectin (3,593 words) [view diff] exact match in snippet view article find links to article
differentiation response to nutrient negative regulation of protein autophosphorylation negative regulation of intracellular protein transport membrane depolarization
Jeffrey L. Price (1,453 words) [view diff] exact match in snippet view article find links to article
named spaghetti, encoding the SPAG protein. SPAG antagonizes DBT autophosphorylation, increasing the stability of DBT during the day by delaying proteasomal
PKC alpha (2,643 words) [view diff] exact match in snippet view article find links to article
Ceryak S, Bouscarel B (Aug 2006). "Bile acids stimulate PKCalpha autophosphorylation and activation: role in the attenuation of prostaglandin E1-induced
ASK1 (2,222 words) [view diff] exact match in snippet view article find links to article
but also the NCC, which leads to full activation of ASK1 through autophosphorylation at threonine 845. ASK1 gene transcription can be induced by inflammatory
DOK2 (1,058 words) [view diff] exact match in snippet view article find links to article
PMID 12522270. Jones N, Chen SH, Sturk C, et al. (2003). "A unique autophosphorylation site on Tie2/Tek mediates Dok-R phosphotyrosine binding domain binding
KaiB (2,981 words) [view diff] exact match in snippet view article find links to article
phosphorylation of the Ser431 residue. This interaction drives SasA autophosphorylation and subsequent phosphotransfer to RpaA. Phospho-RpaA activates the
Phosphoglucosamine mutase (345 words) [view diff] exact match in snippet view article find links to article
Pompeo F, van Heijenoort J, Fassy F, Mengin-Lecreulx D (2000). "Autophosphorylation of phosphoglucosamine mutase from Escherichia coli". J. Bacteriol
NME1-NME2 (206 words) [view diff] exact match in snippet view article find links to article
projection development cellular response to oxidative stress protein autophosphorylation protein complex oligomerization response to growth hormone cellular
RASSF5 (1,022 words) [view diff] exact match in snippet view article find links to article
Ortiz-Vega S, Avruch J (Jul 2004). "Regulation of the MST1 kinase by autophosphorylation, by the growth inhibitory proteins, RASSF1 and NORE1, and by Ras"
Angiotensin-converting enzyme (2,565 words) [view diff] exact match in snippet view article find links to article
proliferation in bone marrow positive regulation of peptidyl-tyrosine autophosphorylation regulation of hematopoietic stem cell proliferation negative regulation
WNK2 (527 words) [view diff] exact match in snippet view article find links to article
Biological process negative regulation of ERK1 and ERK2 cascade protein autophosphorylation protein phosphorylation positive regulation of sodium ion transmembrane
Fibroblast growth factor receptor 2 (1,745 words) [view diff] exact match in snippet view article find links to article
gland morphogenesis regulation of ERK1 and ERK2 cascade protein autophosphorylation mammary gland bud formation pyramidal neuron development lacrimal
AXL receptor tyrosine kinase (2,361 words) [view diff] exact match in snippet view article find links to article
migration, differentiation and survival. Activation of Axl leads to autophosphorylation of its intracellular domain. Proteolytic cleavage of the AXL extracellular
PPP2R5E (915 words) [view diff] exact match in snippet view article find links to article
transduction regulation of phosphoprotein phosphatase activity regulation of protein autophosphorylation protein dephosphorylation Sources:Amigo / QuickGO
Ravi Radhakrishnan (1,323 words) [view diff] exact match in snippet view article find links to article
investigated ErbB3/HER3 kinase activity, revealing its capacity for autophosphorylation and ATP binding despite structural differences, suggesting its role
MST4 (865 words) [view diff] exact match in snippet view article find links to article
hydrogen peroxide-induced cell death protein phosphorylation protein autophosphorylation response to hydrogen peroxide apoptotic process execution phase of
OXSR1 (774 words) [view diff] exact match in snippet view article find links to article
signaling pathway chemokine (C-X-C motif) ligand 12 signaling pathway protein autophosphorylation cellular response to chemokine Sources:Amigo / QuickGO
AAK1 (793 words) [view diff] exact match in snippet view article find links to article
protein stabilization regulation of protein localization protein autophosphorylation positive regulation of Notch signaling pathway protein phosphorylation
RASSF2 (848 words) [view diff] exact match in snippet view article find links to article
positive regulation of JNK cascade positive regulation of protein autophosphorylation skeletal system development regulation of osteoclast differentiation
MST4 (865 words) [view diff] exact match in snippet view article find links to article
hydrogen peroxide-induced cell death protein phosphorylation protein autophosphorylation response to hydrogen peroxide apoptotic process execution phase of
SKAP2 (896 words) [view diff] exact match in snippet view article find links to article
(August 2004). "RAFTK/Pyk2 activation is mediated by trans-acting autophosphorylation in a Src-independent manner". The Journal of Biological Chemistry
AXL receptor tyrosine kinase (2,361 words) [view diff] exact match in snippet view article find links to article
migration, differentiation and survival. Activation of Axl leads to autophosphorylation of its intracellular domain. Proteolytic cleavage of the AXL extracellular
RAS p21 protein activator 1 (1,605 words) [view diff] exact match in snippet view article find links to article
Rübsamen-Waigmann H, Strebhardt K (July 1998). "Tyrosine-614, the major autophosphorylation site of the receptor tyrosine kinase HEK2, functions as multi-docking
Glycogen synthase kinase-3 beta (1,819 words) [view diff] exact match in snippet view article find links to article
export from nucleus positive regulation of GTPase activity protein autophosphorylation cell differentiation negative regulation of protein localization
Yersinia pseudotuberculosis (3,565 words) [view diff] exact match in snippet view article find links to article
states by expressing GTPase activity. YpkA also catalyses serine autophosphorylation, so it may have regulatory functions in Yersinia or undermine host
MAP4K4 (3,301 words) [view diff] exact match in snippet view article find links to article
phosphorylation for the enzyme to assume full activation and is achieved via autophosphorylation or by upstream kinases. To date, MAP4K4 has been found to be expressed
PPP2R5D (1,090 words) [view diff] exact match in snippet view article find links to article
phosphoprotein phosphatase activity negative regulation of peptidyl-threonine phosphorylation regulation of protein autophosphorylation Sources:Amigo / QuickGO
GRAP (621 words) [view diff] exact match in snippet view article find links to article
signaling pathway cell migration cell differentiation peptidyl-tyrosine autophosphorylation regulation of cell population proliferation innate immune response
Nerve growth factor (3,107 words) [view diff] exact match in snippet view article find links to article
drives the homodimerization of the receptor, which in turn causes the autophosphorylation of the tyrosine kinase segment. The tropomyosin receptor kinase A
Aurora kinase A (2,764 words) [view diff] exact match in snippet view article find links to article
meiotic spindle organization mitotic centrosome separation protein autophosphorylation anaphase-promoting complex-dependent catabolic process protein localization
PIM1 (2,973 words) [view diff] exact match in snippet view article find links to article
development protein phosphorylation hyaluronan metabolic process protein autophosphorylation cell cycle cell population proliferation vitamin D receptor signaling
CDKL5 (2,659 words) [view diff] exact match in snippet view article find links to article
GTPase activity positive regulation of dendrite morphogenesis protein autophosphorylation positive regulation of axon extension regulation of dendrite development
CLK1 (1,132 words) [view diff] exact match in snippet view article find links to article
Cellular component cytoplasm nucleus Biological process protein autophosphorylation peptidyl-tyrosine phosphorylation regulation of RNA splicing protein
Vascular endothelial growth factor C (3,104 words) [view diff] exact match in snippet view article find links to article
cell migration signal transduction positive regulation of protein autophosphorylation multicellular organism development morphogenesis of embryonic epithelium
Cyclin T1 (1,358 words) [view diff] exact match in snippet view article find links to article
EM, Meisenhelder J, Thompson NE, Jones KA (September 2000). "CDK9 autophosphorylation regulates high-affinity binding of the human immunodeficiency virus
STK16 (748 words) [view diff] exact match in snippet view article find links to article
cytoplasm membrane cytoplasm cytosol Biological process protein autophosphorylation peptidyl-tyrosine phosphorylation protein phosphorylation transcription
TRIM28 (2,328 words) [view diff] exact match in snippet view article find links to article
protein phosphorylation protein complex oligomerization protein autophosphorylation DNA methylation involved in embryo development Ras protein signal
Insulin (13,818 words) [view diff] exact match in snippet view article find links to article
is triggered by the insulin binding. This activity provokes the autophosphorylation of the β subunits and subsequently the phosphorylation of proteins
ICK (gene) (606 words) [view diff] exact match in snippet view article
kinase within a mitogen-activated protein kinase-like TDY motif by autophosphorylation and cyclin-dependent protein kinase-activating kinase". Mol. Cell
Restriction point (2,746 words) [view diff] exact match in snippet view article find links to article
(RTK) triggers a conformational change and promotes dimerization and autophosphorylation of tyrosine residues on the cytoplasmic tail of the RTKs. These phosphorylated
AKT1 (2,803 words) [view diff] exact match in snippet view article find links to article
insulin stimulus cellular response to decreased oxygen levels protein autophosphorylation inflammatory response positive regulation of fat cell differentiation
CD90 (3,401 words) [view diff] exact match in snippet view article find links to article
signaling pathway positive regulation of GTPase activity protein autophosphorylation negative regulation of protein kinase activity cell adhesion negative
Pseudokinase (1,374 words) [view diff] exact match in snippet view article find links to article
"ErbB3/HER3 intracellular domain is competent to bind ATP and catalyze autophosphorylation". Proceedings of the National Academy of Sciences of the United States
STK39 (605 words) [view diff] exact match in snippet view article find links to article
protein phosphorylation peptidyl-serine phosphorylation protein autophosphorylation ion homeostasis positive regulation of T cell chemotaxis chemokine
MRE11A (2,149 words) [view diff] exact match in snippet view article find links to article
repair via homologous recombination positive regulation of protein autophosphorylation cell population proliferation mitotic G2 DNA damage checkpoint signaling
PPP2R5B (1,121 words) [view diff] exact match in snippet view article find links to article
complex cytoplasm nucleus Biological process regulation of protein autophosphorylation positive regulation of DNA-binding transcription factor activity
PPP2R5A (1,286 words) [view diff] exact match in snippet view article find links to article
membrane protein dephosphorylation regulation of phosphoprotein phosphatase activity regulation of protein autophosphorylation Sources:Amigo / QuickGO
Liprin-alpha-1 (1,160 words) [view diff] exact match in snippet view article find links to article
"Liprin phosphorylation regulates binding to LAR: evidence for liprin autophosphorylation". Biochemistry. 44 (48): 15715–15724. doi:10.1021/bi051434f. PMC 2529169
Martin J. Lohse (1,109 words) [view diff] exact match in snippet view article find links to article
Eva M; Lohse, Martin J (7 December 2008). "A new type of ERK1/2 autophosphorylation causes cardiac hypertrophy". Nature Medicine. 15 (1). Springer Science
GRAP2 (1,459 words) [view diff] exact match in snippet view article find links to article
signaling pathway cell migration cell differentiation peptidyl-tyrosine autophosphorylation regulation of cell population proliferation innate immune response
CLK3 (gene) (664 words) [view diff] exact match in snippet view article
phosphorylation protein phosphorylation regulation of RNA splicing protein autophosphorylation peptidyl-tyrosine phosphorylation Sources:Amigo / QuickGO
TNIK (749 words) [view diff] exact match in snippet view article find links to article
morphogenesis protein phosphorylation cytoskeleton organization protein autophosphorylation protein localization to plasma membrane regulation of mitotic cell
PIM3 (92 words) [view diff] exact match in snippet view article find links to article
Cellular component cytoplasm cytosol Biological process protein autophosphorylation protein phosphorylation cell cycle negative regulation of insulin
PRKX (445 words) [view diff] exact match in snippet view article find links to article
endothelial cell proliferation kidney morphogenesis angiogenesis protein autophosphorylation endothelial cell migration regulation of epithelial cell differentiation
Rad50 (2,139 words) [view diff] exact match in snippet view article find links to article
meiosis double-strand break repair positive regulation of protein autophosphorylation cell cycle viral process double-strand break repair via nonhomologous
SNX8 (4,218 words) [view diff] exact match in snippet view article find links to article
JAK1-SNX8-IKKβ complex. This linkage is essential for IKKβ activation through autophosphorylation at serine in position 177 (as SNX8 lacks enzymatic activity) and
ERRFI1 (932 words) [view diff] exact match in snippet view article find links to article
signaling pathway skin morphogenesis negative regulation of protein autophosphorylation cellular response to platelet-derived growth factor stimulus cellular
GDNF family of ligands (1,125 words) [view diff] exact match in snippet view article find links to article
complex then brings together two molecules of RET, triggering trans-autophosphorylation of specific tyrosine residues within the tyrosine kinase domain of
RAP2B (818 words) [view diff] exact match in snippet view article find links to article
negative regulation of cell migration positive regulation of protein autophosphorylation platelet aggregation signal transduction neutrophil degranulation
SUPT5H (1,231 words) [view diff] exact match in snippet view article find links to article
Suess EM, Meisenhelder J, Thompson NE, Jones KA (Sep 2000). "CDK9 autophosphorylation regulates high-affinity binding of the human immunodeficiency virus
SLK (gene) (969 words) [view diff] exact match in snippet view article
microtubule organization regulation of focal adhesion assembly protein autophosphorylation apoptotic process regulation of cell migration regulation of apoptotic
NEK2 (1,182 words) [view diff] exact match in snippet view article find links to article
centrosome separation mitotic sister chromatid segregation protein autophosphorylation cell cycle negative regulation of centriole-centriole cohesion regulation
UHMK1 (1,122 words) [view diff] exact match in snippet view article find links to article
protein phosphorylation peptidyl-serine phosphorylation protein autophosphorylation neuron projection development positive regulation of translational
Flagellum (7,259 words) [view diff] exact match in snippet view article find links to article
der Does, Chris; Hugel, Thorsten; Albers, Sonja-Verena (2021). "Autophosphorylation of the KaiC-like protein ArlH inhibits oligomerization and interaction
PRKAR2B (1,406 words) [view diff] exact match in snippet view article find links to article
Merlo G, Clair T, Cho-Chung YS (Nov 1995). "Point mutation of the autophosphorylation site or in the nuclear location signal causes protein kinase A RII
CALM2 (1,228 words) [view diff] exact match in snippet view article find links to article
signaling substantia nigra development positive regulation of protein autophosphorylation regulation of cytokinesis positive regulation of phosphoprotein phosphatase
Angiogenesis (5,887 words) [view diff] exact match in snippet view article find links to article
single-chain receptor tyrosine kinases that become activated through autophosphorylation induced by a mechanism of FGF-mediated receptor dimerization. Receptor
NME2 (1,267 words) [view diff] exact match in snippet view article find links to article
projection development cellular response to oxidative stress protein autophosphorylation protein complex oligomerization response to growth hormone cellular
Calcineurin B homologous protein 1 (929 words) [view diff] exact match in snippet view article find links to article
cascade hyaluronan catabolic process negative regulation of protein autophosphorylation negative regulation of protein kinase activity positive regulation
KIT (gene) (4,117 words) [view diff] exact match in snippet view article
differentiation negative regulation of programmed cell death protein autophosphorylation mast cell degranulation inflammatory response positive regulation
RIPK3 (1,078 words) [view diff] exact match in snippet view article find links to article
transcription factor activity apoptotic signaling pathway protein autophosphorylation positive regulation of ligase activity necroptosis regulation of
ROS1 (3,682 words) [view diff] exact match in snippet view article find links to article
spermatogenesis regulation of ERK1 and ERK2 cascade peptidyl-tyrosine autophosphorylation cell population proliferation columnar/cuboidal epithelial cell development
NEK6 (1,164 words) [view diff] exact match in snippet view article find links to article
positive regulation of I-kappaB kinase/NF-kappaB signaling protein autophosphorylation regulation of cellular senescence cell cycle apoptotic process signal
LRRK2 (2,253 words) [view diff] exact match in snippet view article find links to article
receptor signaling pathway regulation of membrane potential protein autophosphorylation regulation of mitochondrial fission regulation of neuron maturation
Akt/PKB signaling pathway (4,072 words) [view diff] exact match in snippet view article find links to article
phosphorylation is not fully understood but may also be influenced by autophosphorylation after Thr308 phosphorylation. After stimulation, the levels of PIP3
RIPK1 (4,951 words) [view diff] exact match in snippet view article find links to article
phosphorylation regulation of ATP:ADP antiporter activity peptidyl-serine autophosphorylation regulation of tumor necrosis factor-mediated signaling pathway positive
Mitogen-activated protein kinase (5,510 words) [view diff] exact match in snippet view article find links to article
through induced N-C dissociation and dimerization-mediated trans autophosphorylation of the MTK1 kinase domain". Molecular and Cellular Biology. 27 (7):
Nerve injury (4,113 words) [view diff] exact match in snippet view article find links to article
tyrosine kinase receptors; binding to the specific receptor yields autophosphorylation and subsequent phosphorylation of tyrosine residues on proteins that
PPP2R5C (1,313 words) [view diff] exact match in snippet view article find links to article
regulation of phosphoprotein phosphatase activity regulation of protein autophosphorylation protein dephosphorylation negative regulation of protein kinase B
Aurora kinase B (4,535 words) [view diff] exact match in snippet view article find links to article
checkpoint signaling positive regulation of telomerase activity protein autophosphorylation negative regulation of B cell apoptotic process negative regulation
MAK (gene) (640 words) [view diff] exact match in snippet view article
organism development protein phosphorylation spermatogenesis protein autophosphorylation regulation of gene expression intracellular signal transduction intraciliary
Interferon (7,065 words) [view diff] exact match in snippet view article find links to article
Envelope Protein E2 Does Not Inhibit PKR by Simple Competition with Autophosphorylation Sites in the RNA-Binding Domain". Journal of Virology. 75 (3): 1265–1273
Paracrine signaling (4,967 words) [view diff] exact match in snippet view article find links to article
transmembrane receptor to another RTK receptor, which causes the autophosphorylation and subsequent conformational change of the homodimerized receptor
Tropomyosin receptor kinase B (4,391 words) [view diff] exact match in snippet view article find links to article
transmembrane receptor protein tyrosine kinase signaling pathway protein autophosphorylation trans-synaptic signaling by neuropeptide, modulating synaptic transmission
NLRP12 (2,194 words) [view diff] exact match in snippet view article find links to article
regulation of inflammatory response negative regulation of protein autophosphorylation positive regulation of MHC class I biosynthetic process negative
ULK1 (1,930 words) [view diff] exact match in snippet view article find links to article
to nutrient levels axon extension response to starvation protein autophosphorylation neuron projection development signal transduction autophagy macroautophagy
Substrate presentation (1,881 words) [view diff] exact match in snippet view article find links to article
cholesterol within lipid rafts. Once dimerized, the receptor undergoes autophosphorylation, which triggers a subsequent phosphorylation cascade. This is a specific
Alok Bhattacharya (2,120 words) [view diff] exact match in snippet view article find links to article
Mansuri; Mrigya Babuta; Sabir Ali; Alok Bhattacharya (January 2016). "Autophosphorylation at Thr279 of Entamoeba histolytica atypical kinase EhAK1 is required
Transcription factor Jun (5,452 words) [view diff] exact match in snippet view article find links to article
transcription by RNA polymerase II negative regulation of protein autophosphorylation membrane depolarization negative regulation of apoptotic process
NLK (1,051 words) [view diff] exact match in snippet view article find links to article
signaling pathway transcription, DNA-templated MAPK cascade protein autophosphorylation transforming growth factor beta receptor signaling pathway Wnt signaling
Richard Ulevitch (315 words) [view diff] exact match in snippet view article find links to article
kinase-independent activation of p38a mediated by TAB 1-dependent autophosphorylation of p38a. Science 295:1291-1294, 2002. "Department of Immunology and
Cyclin H (1,468 words) [view diff] exact match in snippet view article find links to article
Suess EM, Meisenhelder J, Thompson NE, Jones KA (Sep 2000). "CDK9 autophosphorylation regulates high-affinity binding of the human immunodeficiency virus
Cyclin-dependent kinase 5 (5,166 words) [view diff] exact match in snippet view article find links to article
potential excitatory postsynaptic potential synapse assembly protein autophosphorylation positive regulation of actin cytoskeleton reorganization negative
Nibrin (2,609 words) [view diff] exact match in snippet view article find links to article
capping DNA duplex unwinding meiosis positive regulation of protein autophosphorylation isotype switching cell cycle blastocyst growth cell population proliferation
Fibroblast growth factor receptor 1 (5,003 words) [view diff] exact match in snippet view article find links to article
morphogenesis positive regulation of neuron differentiation protein autophosphorylation auditory receptor cell development positive regulation of MAPK cascade
Calmodulin 1 (1,681 words) [view diff] exact match in snippet view article find links to article
peptidyl-threonine phosphorylation positive regulation of protein autophosphorylation regulation of cardiac muscle contraction regulation of cell communication
Chemotaxis (7,443 words) [view diff] exact match in snippet view article find links to article
bind to the receptor. The absence of receptor activation results in autophosphorylation in the histidine kinase, CheA, at a single highly conserved histidine
Neuregulin 1 (4,863 words) [view diff] exact match in snippet view article find links to article
ERBB4 signaling pathway positive regulation of peptidyl-tyrosine autophosphorylation myelination in peripheral nervous system intracellular signal transduction
G protein-coupled receptor (9,384 words) [view diff] exact match in snippet view article find links to article
which has unique ability to increase its binding affinity to CaM by autophosphorylation, making CaM unavailable for the activation of other enzymes. The
BUB1B (2,313 words) [view diff] exact match in snippet view article find links to article
C, Ahmad S, Zhang J, Mao Y (July 2012). "CENP-E--dependent BubR1 autophosphorylation enhances chromosome alignment and the mitotic checkpoint". The Journal
TAF1 (2,422 words) [view diff] exact match in snippet view article find links to article
phosphorylation DNA-templated transcription, initiation protein autophosphorylation cell cycle transcription initiation from RNA polymerase II promoter
Interferon gamma (6,552 words) [view diff] exact match in snippet view article find links to article
IFN-γR1 and IFN-γR2 undergo conformational changes that result in the autophosphorylation and activation of JAK1 and JAK2. This leads to a signaling cascade
Artemis (protein) (1,937 words) [view diff] exact match in snippet view article
Marchetti C, Morrice N, Jeggo PA, Lees-Miller SP (2006-08-23). "DNA-PK autophosphorylation facilitates Artemis endonuclease activity". The EMBO Journal. 25
STK33 (166 words) [view diff] exact match in snippet view article find links to article
intracellular anatomical structure nucleus Biological process protein autophosphorylation protein phosphorylation phosphorylation peptidyl-serine phosphorylation
Phosphoinositide-dependent kinase-1 (2,127 words) [view diff] exact match in snippet view article find links to article
endothelial cell migration cellular response to insulin stimulus protein autophosphorylation regulation of mast cell degranulation peptidyl-threonine phosphorylation
VRK1 (863 words) [view diff] exact match in snippet view article find links to article
membrane reassembly Golgi disassembly regulation of cell shape protein autophosphorylation peptidyl-serine phosphorylation peptidyl-threonine phosphorylation
GPNMB (2,138 words) [view diff] exact match in snippet view article find links to article
positive regulation of cell migration positive regulation of protein autophosphorylation regulation of tissue remodeling negative regulation of T cell proliferation
SMG1 (1,216 words) [view diff] exact match in snippet view article find links to article
biosynthetic process cellular response to DNA damage stimulus protein autophosphorylation phosphorylation regulation of telomere maintenance DNA repair regulation
CALM3 (1,606 words) [view diff] exact match in snippet view article find links to article
peptidyl-threonine phosphorylation positive regulation of protein autophosphorylation regulation of cardiac muscle contraction regulation of cell communication
CSNK1D (14,740 words) [view diff] exact match in snippet view article find links to article
significant. These differences can be explained by various degrees of autophosphorylation of the transcription variants. Based on software analysis of the
PINK1 (2,677 words) [view diff] exact match in snippet view article find links to article
dephosphorylation ubiquitin-dependent protein catabolic process peptidyl-serine autophosphorylation regulation of neuron apoptotic process response to oxidative stress
WNK3 (929 words) [view diff] exact match in snippet view article find links to article
phosphorylation positive regulation of sodium ion transport protein autophosphorylation positive regulation of sodium ion transmembrane transporter activity
P110δ (2,500 words) [view diff] exact match in snippet view article find links to article
M, Anderson S, Brennan P, Ward SG, Waterfield MD (March 1999). "Autophosphorylation of p110delta phosphoinositide 3-kinase: a new paradigm for the regulation
CSNK2B (2,258 words) [view diff] exact match in snippet view article find links to article
subunit of casein kinase II in human A431 cells. Identification of the autophosphorylation site and a site phosphorylated by p34cdc2". J. Biol. Chem. 266 (30):
Ataxia–telangiectasia (10,766 words) [view diff] exact match in snippet view article find links to article
(January 2003). "DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation". Nature. 421 (6922): 499–506. Bibcode:2003Natur
Adapter molecule crk (2,943 words) [view diff] exact match in snippet view article find links to article
PMID 2173144. Schaller MD, Hildebrand JD, Shannon JD, et al. (1994). "Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding
DNA-PKcs (3,754 words) [view diff] exact match in snippet view article find links to article
been identified as substrates for the kinase activity of DNA-PK. Autophosphorylation of DNA-PKcs appears to play a key role in NHEJ and is thought to
DNA repair (15,900 words) [view diff] exact match in snippet view article find links to article
(January 2003). "DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation". Nature. 421 (6922): 499–506. Bibcode:2003Natur
Archaellum (3,642 words) [view diff] exact match in snippet view article find links to article
J, Chaudhury P, Kumariya R, van der Does C, et al. (July 2021). "Autophosphorylation of the KaiC-like protein ArlH inhibits oligomerisation and interaction
Nucleotide pyrophosphatase/phosphodiesterase (1,857 words) [view diff] exact match in snippet view article find links to article
Mercuri, Francesca A.; Sali, Adnan; Goding, James W. (1995-03-01). "Autophosphorylation of PC-1 (Alkaline Phosphodiesterase I/Nucleotide Pyrophosphatase)
Interleukin-1 receptor associated kinase (3,637 words) [view diff] exact match in snippet view article find links to article
and IRAK-4, allowing IRAK-4 to phosphorylate IRAK-1, leading to autophosphorylation and activation of IRAK-1 [1,2]. IRAK-4 is critical for IL-1R and
MTOR (12,661 words) [view diff] exact match in snippet view article find links to article
regulation of peptidyl-tyrosine phosphorylation social behavior protein autophosphorylation negative regulation of cholangiocyte apoptotic process regulation
Gcn2 (2,065 words) [view diff] exact match in snippet view article find links to article
results from a conformation that facilitates ATP binding, leading to autophosphorylation of an activation loop which leads to maximal GCN2 kinase activity
Autoinducer (3,939 words) [view diff] exact match in snippet view article find links to article
has reached a threshold concentration. Detection is followed by autophosphorylation of ComD, which in turn, phosphorylates ComE. ComE is a response regulator
Alexei Kharitonenkov (2,468 words) [view diff] exact match in snippet view article find links to article
PMID 2481508. Kharitonenkov, A. I.; Bulargina, T. V. (1991-02-01). "[Autophosphorylation of EGF receptors in the A431 cell line with an increased intracellular
RIOK1 (1,377 words) [view diff] exact match in snippet view article find links to article
Examples: P62166, O14776. The mutation (D324A) in RIOK1 abolishes autophosphorylation activity, enhances association with pre-40S ribosomal subunits and
IQGAP1 (3,922 words) [view diff] exact match in snippet view article find links to article
focal adhesion assembly positive regulation of peptidyl-tyrosine autophosphorylation positive regulation of GTPase activity positive regulation of protein
Denise Manahan-Vaughan (2,728 words) [view diff] exact match in snippet view article find links to article
PMID 26042007. Goh J, Manahan-Vaughan D (May 2015). "Role of inhibitory autophosphorylation of calcium/calmodulin-dependent kinase II (αCAMKII) in persistent
GRB2 (9,365 words) [view diff] exact match in snippet view article find links to article
organization cell migration cell differentiation peptidyl-tyrosine autophosphorylation regulation of cell population proliferation innate immune response
Cholera autoinducer-1 (1,895 words) [view diff] exact match in snippet view article find links to article
binding to CqsS includes multiple regulatory pathways. CqsS undergoes autophosphorylation which involves the transfer of the phosphate group to LuxO, a response
Double-strand break repair model (4,324 words) [view diff] exact match in snippet view article find links to article
Morotomi-Yano K, Jakob B, Taucher-Scholz G, et al. (April 2007). "Autophosphorylation of DNA-PKCS regulates its dynamics at DNA double-strand breaks".
SULF1 (6,584 words) [view diff] exact match in snippet view article find links to article
Receptor (FGFR) to cause receptor dimerization, activation, and autophosphorylation, which then leads to induction of the mitogen-activated protein kinase
Alcino J. Silva (6,318 words) [view diff] exact match in snippet view article find links to article
Giese, K.P.; Fedorov, N.B.; Filipkowski, R.K.; Silva, A.J. (1998). "Autophosphorylation at Thr286 of the alpha calcium-calmodulin kinase II in LTP and learning"
Molecular and epigenetic mechanisms of alcoholism (6,687 words) [view diff] exact match in snippet view article find links to article
receptors whose subsequent activation results in dimerization and autophosphorylation of the receptor. In its phosphorylated form, TrkB receptors recruit
Mastocytoma in dogs (5,640 words) [view diff] exact match in snippet view article find links to article
 481–493, ISSN 1944-7930. PMID 22204765. Y. Takeuchi et al.: Aberrant autophosphorylation of c-Kit receptor in canine mast cell tumor cell lines. In: Veterinary