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searching for Autophosphorylation 316 found (388 total)

EEF2K (1,651 words) [view diff] exact match in snippet view article find links to article

activate the kinase domain, triggering rapid autophosphorylation of Thr-348. In the second step, autophosphorylation of Thr-348 leads to a conformational change

Elongation factor 2 kinase (893 words) [view diff] exact match in snippet view article find links to article

activate the kinase domain, triggering rapid autophosphorylation of Thr-348. In the second step, autophosphorylation of Thr-348 leads to a conformational change

TXK (gene) (718 words) [view diff] exact match in snippet view article

Suzuki N, Takeno M, et al. (2002). "Evidence of autophosphorylation in Txk: Y91 is an autophosphorylation site". Biol. Pharm. Bull. 25 (6): 718–21. doi:10

PLK4 (2,217 words) [view diff] exact match in snippet view article find links to article

which facilitates oligomerization, targeting, and promotes trans-autophosphorylation, limiting centriole duplication to once per cell cycle. Inhibitors

PTK6 (999 words) [view diff] exact match in snippet view article find links to article

epithelial tissues. The encoded protein has been shown to undergo autophosphorylation. Overexpression of this gene in mammary epithelial cells leads to

Megakaryocyte-associated tyrosine kinase (1,177 words) [view diff] exact match in snippet view article find links to article

lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal

CPS operon (219 words) [view diff] exact match in snippet view article find links to article

proteins. Reduced levels of membrane-derived oligosaccharides result in autophosphorylation of RcsC. This results in a phosphate group being transferred from

YES1 (1,030 words) [view diff] exact match in snippet view article find links to article

S2CID 45071719. Toshima J, Ohashi K, Iwashita S, Mizuno K (1995). "Autophosphorylation activity and association with Src family kinase of Sky receptor tyrosine

CAMK2B (1,157 words) [view diff] exact match in snippet view article find links to article

protein kinase II: identification of threonine-286 as the autophosphorylation site in the alpha subunit associated with the generation of Ca2+-independent

FER (gene) (968 words) [view diff] exact match in snippet view article

Priel-Halachmi S, et al. (2000). "N-terminal sequences direct the autophosphorylation states of the FER tyrosine kinases in vivo". Biochemistry. 39 (36):

DDR1 (1,207 words) [view diff] exact match in snippet view article find links to article

discoideum protein discoidin I in their extracellular domain. Its autophosphorylation is achieved by all collagens so far tested (type I to type VI). A

Tyrosine-protein kinase CSK (977 words) [view diff] exact match in snippet view article find links to article

regulation of phagocytosis, dendrocyte differentiation, peptidyl-tyrosine autophosphorylation, platelet activation, positive regulation of MAP kinase activity

RET proto-oncogene (2,385 words) [view diff] exact match in snippet view article find links to article

complex then brings together two molecules of RET, triggering trans-autophosphorylation of specific tyrosine residues within the tyrosine kinase domain of

ATP13A2 (712 words) [view diff] exact match in snippet view article find links to article

response to manganese ion cellular iron ion homeostasis protein autophosphorylation cellular zinc ion homeostasis autophagosome organization regulation

ZAP70 (2,769 words) [view diff] exact match in snippet view article find links to article

ZAP-70 to phosphorylated T-cell receptor zeta and eta enhances its autophosphorylation and generates specific binding sites for SH2 domain-containing proteins"

TTK (gene) (836 words) [view diff] exact match in snippet view article

Mattison CP, Old WM, Steiner E, et al. (2007). "Mps1 activation loop autophosphorylation enhances kinase activity". J. Biol. Chem. 282 (42): 30553–61. doi:10

Proto-oncogene tyrosine-protein kinase Src (2,795 words) [view diff] exact match in snippet view article find links to article

the SH3, SH2 and kinase domains and the autophosphorylation of the residue tyrosine 416. The autophosphorylation of Y416 as well as phosphorylation of selected

Calcium/calmodulin-dependent protein kinase type II subunit alpha (1,466 words) [view diff] exact match in snippet view article find links to article

calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding

EPHB3 (933 words) [view diff] exact match in snippet view article find links to article

Rübsamen-Waigmann H, Strebhardt K (Jul 1998). "Tyrosine-614, the major autophosphorylation site of the receptor tyrosine kinase HEK2, functions as multi-docking

DAPK2 (700 words) [view diff] exact match in snippet view article find links to article

PMID 10629061. Shani G, Henis-Korenblit S, Jona G, et al. (2001). "Autophosphorylation restrains the apoptotic activity of DRP-1 kinase by controlling dimerization

Protein kinase (1,616 words) [view diff] exact match in snippet view article find links to article

extracellular signal. Trans-autophosphorylation (phosphorylation by the other kinase in the dimer) of the kinase. Autophosphorylation stabilizes the active

MAP3K11 (1,259 words) [view diff] exact match in snippet view article find links to article

activation loop is the key to mixed lineage kinase-3 activation via both autophosphorylation and hematopoietic progenitor kinase 1 phosphorylation". J. Biol.

Tyrosine-protein kinase Fes/Fps (577 words) [view diff] exact match in snippet view article find links to article

polymerization peptidyl-tyrosine autophosphorylation regulation of cell differentiation protein autophosphorylation peptidyl-tyrosine phosphorylation

Lck (4,453 words) [view diff] exact match in snippet view article find links to article

coreceptor-free LCK via its cytoplasmic domain, promoting the LCK autophosphorylation. There is very little understanding of the role of CD45 isoforms

Vascular endothelial growth factor A (3,053 words) [view diff] exact match in snippet view article find links to article

within the molecule in a process called auto-phosphorylation. The autophosphorylation of these amino acids allows for signalling molecules within to the

TYRO3 (962 words) [view diff] exact match in snippet view article find links to article

PMID 7511603. Toshima J, Ohashi K, Iwashita S, Mizuno K (1995). "Autophosphorylation activity and association with Src family kinase of Sky receptor tyrosine

Ste5 (702 words) [view diff] exact match in snippet view article find links to article

is also involved in down regulating of signalling. It stimulates autophosphorylation of Fus3, which results in phosphorylation of Ste5, causing a downregulation

BMX (gene) (1,196 words) [view diff] exact match in snippet view article

of cell population proliferation peptidyl-tyrosine autophosphorylation protein autophosphorylation mesoderm development innate immune response signal

DAPK1 (1,170 words) [view diff] exact match in snippet view article find links to article

death-associated protein kinase is controlled by a unique inhibitory autophosphorylation-based mechanism". The Journal of Biological Chemistry. 276 (50):

Janus kinase 3 (5,166 words) [view diff] exact match in snippet view article find links to article

using Jak3-wt or villin/gelsolin-wt as substrate showed that Jak3 autophosphorylation was the rate-limiting step during interactions between Jak3 and cytoskeletal

DAPK1 (1,170 words) [view diff] exact match in snippet view article find links to article

death-associated protein kinase is controlled by a unique inhibitory autophosphorylation-based mechanism". The Journal of Biological Chemistry. 276 (50):

ERN1 (1,889 words) [view diff] exact match in snippet view article find links to article

possesses two functional enzymatic domains, an endonuclease and a trans-autophosphorylation kinase domain. Upon activation, IRE1α oligomerizes and carries out

FGR (gene) (1,235 words) [view diff] exact match in snippet view article

of cell shape peptidyl-tyrosine autophosphorylation integrin-mediated signaling pathway protein autophosphorylation positive regulation of phosphatidylinositol

Fus3 (742 words) [view diff] exact match in snippet view article find links to article

locates to the nucleus. One regulator of Fus3 is Ste5. Ste5 causes autophosphorylation of one of two locations modulated by the MAPK kinase Ste7 (the main

IRAK4 (2,530 words) [view diff] exact match in snippet view article find links to article

in a decrease in the kinase activity of IRAK4. A structure of the autophosphorylation of the activation loop has been determined in which the activation

Epidermal growth factor receptor (6,879 words) [view diff] exact match in snippet view article find links to article

intrinsic intracellular protein-tyrosine kinase activity. As a result, autophosphorylation of several tyrosine (Y) residues in the C-terminal domain of EGFR

DNAJC3 (1,492 words) [view diff] exact match in snippet view article find links to article

double-stranded RNA-dependent protein kinase, PKR, to regulate its autophosphorylation and activity". The Journal of Biological Chemistry. 271 (3): 1702–7

Non-receptor tyrosine kinase (2,716 words) [view diff] exact match in snippet view article find links to article

enzymatic activity. Activation loop phosphorylation occurs via trans-autophosphorylation or phosphorylation by different nRTKs. It is possible to negatively

ERBB3 (2,750 words) [view diff] exact match in snippet view article find links to article

activated through autophosphorylation upon ligand binding, ErbB3 was found to be kinase impaired, having only 1/1000 the autophosphorylation activity of EGFR

CLK2 (948 words) [view diff] exact match in snippet view article find links to article

PDBe-KB. Lee K, Du C, Horn M, Rabinow L (Nov 1996). "Activity and autophosphorylation of LAMMER protein kinases". The Journal of Biological Chemistry.

GRK5 (1,986 words) [view diff] exact match in snippet view article find links to article

P, Gurevich VV, Benovic JL (Apr 1994). "Phospholipid-stimulated autophosphorylation activates the G protein-coupled receptor kinase GRK5". The Journal

ERBB4 (1,597 words) [view diff] exact match in snippet view article find links to article

positive regulation of protein localization to cell surface protein autophosphorylation cardiac muscle tissue regeneration positive regulation of phosphatidylinositol

Kinase insert domain receptor (794 words) [view diff] exact match in snippet view article find links to article

regulation of ERK1 and ERK2 cascade peptidyl-tyrosine autophosphorylation protein autophosphorylation positive regulation of focal adhesion assembly positive

PTK2B (1,887 words) [view diff] exact match in snippet view article find links to article

positive regulation of peptidyl-tyrosine phosphorylation protein autophosphorylation innate immune response negative regulation of myeloid cell differentiation

Integrated stress response (1,625 words) [view diff] exact match in snippet view article find links to article

from the luminal domain. This causes PERK to dimerize, leading to autophosphorylation and activation. The activated PERK kinase will then phosphorylate

Bruton's tyrosine kinase (2,389 words) [view diff] exact match in snippet view article find links to article

development intracellular signal transduction peptidyl-tyrosine autophosphorylation B cell activation positive regulation of NF-kappaB transcription

Protein kinase R (4,105 words) [view diff] exact match in snippet view article find links to article

double-stranded RNA-dependent protein kinase, PKR, to regulate its autophosphorylation and activity". The Journal of Biological Chemistry. 271 (3): 1702–1707

EPH receptor A4 (766 words) [view diff] exact match in snippet view article find links to article

PMID 8125298. Ellis C, Kasmi F, Ganju P, et al. (1996). "A juxtamembrane autophosphorylation site in the Eph family receptor tyrosine kinase, Sek, mediates high

SIK1 (375 words) [view diff] exact match in snippet view article find links to article

of mitotic cell cycle regulation of cell differentiation protein autophosphorylation cell cycle positive regulation of anoikis entrainment of circadian

LYN (3,807 words) [view diff] exact match in snippet view article find links to article

turn, activation of the insulin receptor has been shown to increase autophosphorylation of Lyn suggesting a possible feedback loop. The insulin secretagogue

MAP3K9 (462 words) [view diff] exact match in snippet view article find links to article

DNA-templated protein phosphorylation positive regulation of apoptotic process protein autophosphorylation apoptotic process MAPK cascade Sources:Amigo / QuickGO

PAK2 (2,164 words) [view diff] exact match in snippet view article find links to article

1995). "A novel serine kinase activated by rac1/CDC42Hs-dependent autophosphorylation is related to PAK65 and STE20". The EMBO Journal. 14 (9): 1970–8

STYK1 (476 words) [view diff] exact match in snippet view article find links to article

membrane plasma membrane membrane Biological process peptidyl-tyrosine autophosphorylation cell differentiation protein phosphorylation innate immune response

Janus kinase 1 (2,423 words) [view diff] exact match in snippet view article find links to article

interleukin-2-mediated signaling pathway peptidyl-tyrosine autophosphorylation protein autophosphorylation cell migration innate immune response interleukin-12-mediated

Janus kinase (974 words) [view diff] exact match in snippet view article find links to article

bringing the two JAKs close enough to phosphorylate each other. The JAK autophosphorylation induces a conformational change within itself, enabling it to transduce

MAP3K13 (451 words) [view diff] exact match in snippet view article find links to article

process phosphorylation JNK cascade protein phosphorylation protein autophosphorylation positive regulation of NF-kappaB transcription factor activity MAPK

TSSK2 (414 words) [view diff] exact match in snippet view article find links to article

development protein phosphorylation spermatogenesis spermatid development protein autophosphorylation peptidyl-serine phosphorylation Sources:Amigo / QuickGO

Potato carboxypeptidase inhibitor (605 words) [view diff] exact match in snippet view article find links to article

action is inhibition of receptor dimerization and receptor trans-autophosphorylation induced by epidermal growth factor (EGF). PCI blocks the formation

CDK12 (514 words) [view diff] exact match in snippet view article find links to article

phosphorylation regulation of RNA splicing RNA splicing protein autophosphorylation regulation of MAP kinase activity transcription elongation from RNA

CHEK2 (2,797 words) [view diff] exact match in snippet view article find links to article

form the dimer. After the protein dimerizes the KD is activated via autophosphorylation. Once the KD is activated the CHK2 dimer dissociates. The CHEK2 gene

TESK1 (740 words) [view diff] exact match in snippet view article find links to article

activity of testis-specific protein kinase 1 and its regulation by autophosphorylation of serine-215 within the activation loop". J. Biol. Chem. 274 (17):

HCK (2,331 words) [view diff] exact match in snippet view article find links to article

assembly peptidyl-tyrosine autophosphorylation phagocytosis integrin-mediated signaling pathway protein autophosphorylation peptidyl-tyrosine phosphorylation

Pedunculagin (519 words) [view diff] exact match in snippet view article find links to article

"Further characterization of galloyl pedunculagin as an effective autophosphorylation inhibitor of C-kinase in vitro". Biological & Pharmaceutical Bulletin

TAOK2 (953 words) [view diff] exact match in snippet view article find links to article

protein autophosphorylation activation of protein kinase activity regulation of actin cytoskeleton organization protein autophosphorylation basal dendrite

MAPKAPK5 (756 words) [view diff] exact match in snippet view article find links to article

phosphorylation positive regulation of telomerase activity protein autophosphorylation Ras protein signal transduction regulation of translation signal

KSR1 (553 words) [view diff] exact match in snippet view article find links to article

(2011). "KSR1 is a functional protein kinase capable of serine autophosphorylation and direct phosphorylation of MEK1". Exp. Cell Res. 317 (4): 452–63

EIF2AK4 (501 words) [view diff] exact match in snippet view article find links to article

endoplasmic reticulum stress induction by virus of host autophagy protein autophosphorylation cell cycle negative regulation by host of viral genome replication

Receptor tyrosine kinase (3,078 words) [view diff] exact match in snippet view article find links to article

the kinase activity of these receptors, which catalyses receptor autophosphorylation and tyrosine phosphorylation of RTK substrates. A kinase is a type

INSRR (657 words) [view diff] exact match in snippet view article find links to article

axon Biological process actin cytoskeleton reorganization protein autophosphorylation protein phosphorylation cellular response to alkaline pH male sex

Tropomyosin receptor kinase C (3,936 words) [view diff] exact match in snippet view article find links to article

ligand binding induces receptor dimerization followed by trans-autophosphorylation on conserved tyrosine in the intracellular (cytoplasmic) domain of

Ectonucleotide pyrophosphatase/phosphodiesterase 1 (1,444 words) [view diff] exact match in snippet view article find links to article

PMID 2211644. Belli SI, Mercuri FA, Sali A, Goding JW (1995). "Autophosphorylation of PC-1 (alkaline phosphodiesterase I/nucleotide pyrophosphatase)

STK10 (595 words) [view diff] exact match in snippet view article find links to article

aggregation phosphorylation regulation of lymphocyte migration protein autophosphorylation cell cycle protein phosphorylation neutrophil degranulation regulation

TAB1 (2,250 words) [view diff] exact match in snippet view article find links to article

"MAPKK-independent activation of p38alpha mediated by TAB1-dependent autophosphorylation of p38alpha". Science. 295 (5558): 1291–4. Bibcode:2002Sci...295

Ectonucleotide pyrophosphatase/phosphodiesterase 1 (1,444 words) [view diff] exact match in snippet view article find links to article

PMID 2211644. Belli SI, Mercuri FA, Sali A, Goding JW (1995). "Autophosphorylation of PC-1 (alkaline phosphodiesterase I/nucleotide pyrophosphatase)

STK10 (595 words) [view diff] exact match in snippet view article find links to article

aggregation phosphorylation regulation of lymphocyte migration protein autophosphorylation cell cycle protein phosphorylation neutrophil degranulation regulation

Fyn-related kinase (575 words) [view diff] exact match in snippet view article find links to article

transcription by RNA polymerase II protein phosphorylation peptidyl-tyrosine autophosphorylation innate immune response negative regulation of cell population proliferation

DAPK3 (843 words) [view diff] exact match in snippet view article find links to article

response to interferon-gamma apoptotic signaling pathway protein autophosphorylation regulation of translation regulation of mitotic nuclear division

DYRK1B (894 words) [view diff] exact match in snippet view article find links to article

phosphorylation peptidyl-tyrosine phosphorylation myoblast fusion adipose tissue development phosphorylation protein autophosphorylation Sources:Amigo / QuickGO

TRPM7 (421 words) [view diff] exact match in snippet view article find links to article

protein phosphorylation calcium ion transmembrane transport protein autophosphorylation necroptosis calcium ion transport transmembrane transport Sources:Amigo

MKNK2 (834 words) [view diff] exact match in snippet view article find links to article

extrinsic apoptotic signaling pathway in absence of ligand protein autophosphorylation regulation of translation apoptotic process hemopoiesis Sources:Amigo

Janus kinase 2 (3,166 words) [view diff] exact match in snippet view article find links to article

peptidyl-tyrosine phosphorylation erythrocyte differentiation protein autophosphorylation platelet-derived growth factor receptor signaling pathway positive

FYN (4,778 words) [view diff] exact match in snippet view article find links to article

ZAP-70 to phosphorylated T-cell receptor zeta and eta enhances its autophosphorylation and generates specific binding sites for SH2 domain-containing proteins"

Integrin-linked kinase (2,654 words) [view diff] exact match in snippet view article find links to article

direct phosphorylation target of CML9. With the addition of CML9, autophosphorylation of ILK1 is diminished, the present irrespective of calcium available

PDGFB (434 words) [view diff] exact match in snippet view article find links to article

multicellular organism development positive regulation of protein autophosphorylation positive regulation of reactive oxygen species metabolic process

Myosin-IIIa (637 words) [view diff] exact match in snippet view article find links to article

phosphorylation response to stimulus protein phosphorylation protein autophosphorylation visual perception sensory perception of sound cochlea morphogenesis

PASK (796 words) [view diff] exact match in snippet view article find links to article

Biological process regulation of respiratory gaseous exchange protein autophosphorylation negative regulation of glycogen biosynthetic process positive regulation

Timothy syndrome (1,230 words) [view diff] exact match in snippet view article find links to article

impulse propagation. Single cell studies identified that CaMKII autophosphorylation reduced the peak sodium current, thus causing the slowing of conduction

LMTK2 (813 words) [view diff] exact match in snippet view article find links to article

recycling peptidyl-serine phosphorylation endocytic recycling protein autophosphorylation peptidyl-threonine phosphorylation negative regulation of phosphoprotein

MAP3K12 (1,255 words) [view diff] exact match in snippet view article find links to article

phosphorylation JNK cascade peptidyl-serine phosphorylation protein autophosphorylation peptidyl-threonine phosphorylation negative regulation of motor neuron

PRKCG (526 words) [view diff] exact match in snippet view article find links to article

rhythm peptidyl-serine phosphorylation learning or memory protein autophosphorylation negative regulation of proteasomal protein catabolic process regulation

CAMK4 (1,126 words) [view diff] exact match in snippet view article find links to article

differentiation long-term memory peptidyl-serine phosphorylation protein autophosphorylation inflammatory response signal transduction Sources:Amigo / QuickGO

Tyrosine-protein kinase BLK (847 words) [view diff] exact match in snippet view article find links to article

phosphorylation regulation of cell population proliferation peptidyl-tyrosine autophosphorylation innate immune response positive regulation of insulin secretion cell

CD79B (987 words) [view diff] exact match in snippet view article find links to article

alpha/Ig beta immunoreceptor tyrosine activation motif binding and autophosphorylation". J. Biol. Chem. 270 (19): 11590–4. doi:10.1074/jbc.270.19.11590

MAPK15 (1,095 words) [view diff] exact match in snippet view article find links to article

positive regulation of telomerase activity MAPK cascade protein autophosphorylation regulation of gene expression regulation of autophagy protein localization

MYLK2 (777 words) [view diff] exact match in snippet view article find links to article

of gene expression skeletal muscle cell differentiation protein autophosphorylation peptidyl-threonine phosphorylation striated muscle contraction peptidyl-serine

VEGFR1 (1,086 words) [view diff] exact match in snippet view article find links to article

receptor signaling pathway embryonic morphogenesis angiogenesis protein autophosphorylation positive regulation of phosphatidylinositol 3-kinase signaling peptidyl-tyrosine

AKT3 (1,189 words) [view diff] exact match in snippet view article find links to article

"Identification of serine 643 of protein kinase C-delta as an important autophosphorylation site for its enzymatic activity". J. Biol. Chem. 272 (39): 24550–5

PRKD2 (940 words) [view diff] exact match in snippet view article find links to article

vascular endothelial growth factor receptor signaling pathway protein autophosphorylation cellular response to vascular endothelial growth factor stimulus

PLK3 (1,212 words) [view diff] exact match in snippet view article find links to article

(2002). "Phosphorylation of threonine 68 promotes oligomerization and autophosphorylation of the Chk2 protein kinase via the forkhead-associated domain". J

EIF2S1 (1,448 words) [view diff] exact match in snippet view article find links to article

stress transmembrane transport translational initiation protein autophosphorylation regulation of translation regulation of translational initiation

MARK2 (1,143 words) [view diff] exact match in snippet view article find links to article

polarity positive regulation of neuron projection development protein autophosphorylation peptidyl-threonine phosphorylation activation of protein kinase activity

GFRA2 (gene) (812 words) [view diff] exact match in snippet view article

guidance positive regulation of peptidyl-serine phosphorylation of STAT protein negative regulation of protein autophosphorylation Sources:Amigo / QuickGO

MOS (gene) (669 words) [view diff] exact match in snippet view article

Cellular component cytoplasm cytosol Biological process protein autophosphorylation establishment of meiotic spindle orientation chromatin organization

PIAS1 (1,351 words) [view diff] exact match in snippet view article find links to article

"PIAS1-mediated sumoylation of focal adhesion kinase activates its autophosphorylation". J. Biol. Chem. 278 (48): 47434–47440. doi:10.1074/jbc.M308562200

ABL (gene) (3,496 words) [view diff] exact match in snippet view article

binding cell adhesion regulation of autophagy peptidyl-tyrosine autophosphorylation alpha-beta T cell differentiation regulation of cellular senescence

Zalutumumab (806 words) [view diff] exact match in snippet view article find links to article

epidermal growth factor or TGF alpha, dimerization occurs, leading to autophosphorylation on the intracellular tyrosine residues. Following phosphorylation

MKNK1 (1,031 words) [view diff] exact match in snippet view article find links to article

signal transduction phosphorylation protein phosphorylation protein autophosphorylation regulation of translation peptidyl-serine phosphorylation Sources:Amigo

MAPK11 (1,233 words) [view diff] exact match in snippet view article find links to article

"MAPKK-independent activation of p38alpha mediated by TAB1-dependent autophosphorylation of p38alpha". Science. 295 (5558): 1291–4. Bibcode:2002Sci...295

MAP2K2 (1,231 words) [view diff] exact match in snippet view article find links to article

regulation of early endosome to late endosome transport peptidyl-serine autophosphorylation negative regulation of gene expression positive regulation of protein

PAK1 (5,251 words) [view diff] exact match in snippet view article find links to article

this autoinhibition and initiate conformational rearrangements and autophosphorylation events leading to kinase activation. IPA-3 (1,1′-disulfanediyldinaphthalen-2-ol)

PDGFD (793 words) [view diff] exact match in snippet view article find links to article

regulation of monocyte extravasation positive regulation of protein autophosphorylation positive regulation of cell population proliferation positive regulation

MARK3 (1,217 words) [view diff] exact match in snippet view article find links to article

phosphorylation positive regulation of protein binding intracellular signal transduction peptidyl-serine autophosphorylation Sources:Amigo / QuickGO

MAP3K10 (1,089 words) [view diff] exact match in snippet view article find links to article

phosphorylation JNK cascade peptidyl-serine phosphorylation protein autophosphorylation smoothened signaling pathway peptidyl-threonine phosphorylation negative

Protein kinase D1 (1,304 words) [view diff] exact match in snippet view article find links to article

kinase/NF-kappaB signaling integrin-mediated signaling pathway protein autophosphorylation cellular response to oxidative stress cellular response to vascular

CAMK2D (872 words) [view diff] exact match in snippet view article find links to article

phosphorylation endoplasmic reticulum calcium ion homeostasis protein autophosphorylation relaxation of cardiac muscle cardiac muscle cell contraction regulation

CAMK2G (1,113 words) [view diff] exact match in snippet view article find links to article

oligomerization regulation of cellular response to heat protein autophosphorylation regulation of skeletal muscle adaptation calcium ion transport protein

CAMKK2 (1,817 words) [view diff] exact match in snippet view article find links to article

determined. The identified isoforms exhibit a distinct ability to undergo autophosphorylation and to phosphorylate the downstream kinases. GRCh38: Ensembl release

MELK (977 words) [view diff] exact match in snippet view article find links to article

cell proliferation positive regulation of apoptotic process protein autophosphorylation cell cycle cell population proliferation apoptotic process peptidyl-tyrosine

Cyclin-dependent kinase 9 (1,460 words) [view diff] exact match in snippet view article find links to article

EM, Meisenhelder J, Thompson NE, Jones KA (September 2000). "CDK9 autophosphorylation regulates high-affinity binding of the human immunodeficiency virus

BCR (gene) (1,541 words) [view diff] exact match in snippet view article

regulation of neutrophil degranulation inner ear morphogenesis protein autophosphorylation platelet-derived growth factor receptor signaling pathway regulation

MERTK (1,093 words) [view diff] exact match in snippet view article find links to article

Templeton D, Kung HJ (August 1996). "Identification of the major autophosphorylation sites of Nyk/Mer, an NCAM-related receptor tyrosine kinase". The

EIF2AK3 (1,365 words) [view diff] exact match in snippet view article find links to article

phosphorylation in response to endoplasmic reticulum stress protein autophosphorylation positive regulation of vascular endothelial growth factor production

Ephrin receptor (3,454 words) [view diff] exact match in snippet view article find links to article

repress downstream signaling cascades. The structure of the trans-autophosphorylation of the juxtamembrane region of EPHA2 has been observed within a crystal

MAP3K2 (1,505 words) [view diff] exact match in snippet view article find links to article

MEKK2 is activated through homodimerization and subsequent trans-autophosphorylation at MEKK2-S519. MEKK2 is regulated by 14-3-3 proteins which bind to

Marina Picciotto (1,359 words) [view diff] exact match in snippet view article find links to article

"Calcium/calmodulin-dependent protein kinase I - cDNA cloning and identification of autophosphorylation site". J. Biol. Chem. 268 (35): 26512–26521. doi:10.1016/S0021-9258(19)74343-9

FLT4 (1,183 words) [view diff] exact match in snippet view article find links to article

proliferation positive regulation of ERK1 and ERK2 cascade protein autophosphorylation positive regulation of vascular endothelial growth factor production

Ataxia telangiectasia and Rad3 related (3,425 words) [view diff] exact match in snippet view article find links to article

(January 2003). "DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation". Nature. 421 (6922): 499–506. Bibcode:2003Natur

MAPKAPK3 (1,042 words) [view diff] exact match in snippet view article find links to article

pathway macropinocytosis peptidyl-serine phosphorylation protein autophosphorylation signal transduction toll-like receptor signaling pathway MAPK cascade

MAPK3 (1,178 words) [view diff] exact match in snippet view article find links to article

activity positive regulation of telomerase activity peptidyl-tyrosine autophosphorylation sensory perception of pain positive regulation of cyclase activity

KdpD/KdpE two-component system (1,806 words) [view diff] exact match in snippet view article find links to article

potassium affects the autophosphorylation of KdpD. High concentrations of intracellular potassium inhibit the autophosphorylation of KdpD. KdpD also detects

PDGFRB (3,403 words) [view diff] exact match in snippet view article find links to article

Wernstedt C, Claesson-Welsh L, Heldin CH (October 1994). "A unique autophosphorylation site in the platelet-derived growth factor alpha receptor from a

CAD protein (1,156 words) [view diff] exact match in snippet view article find links to article

biosynthetic process pyrimidine nucleotide biosynthetic process protein autophosphorylation metabolism peptidyl-threonine phosphorylation 'de novo' UMP biosynthetic

Signal transduction (7,624 words) [view diff] exact match in snippet view article find links to article

The interaction between the cytoplasmic domains stimulates the autophosphorylation of tyrosine residues within the intracellular kinase domains of the

ACVR1B (1,542 words) [view diff] exact match in snippet view article find links to article

of signal transduction negative regulation of cell growth protein autophosphorylation peptidyl-threonine phosphorylation signal transduction positive regulation

TEK tyrosine kinase (1,695 words) [view diff] exact match in snippet view article find links to article

ERK1 and ERK2 cascade negative regulation of angiogenesis protein autophosphorylation positive regulation of focal adhesion assembly regulation of establishment

EPH receptor A1 (622 words) [view diff] exact match in snippet view article find links to article

angiogenesis positive regulation of cell population proliferation protein autophosphorylation peptidyl-tyrosine phosphorylation substrate adhesion-dependent cell

Nucleoside-diphosphate kinase (2,538 words) [view diff] exact match in snippet view article find links to article

kinase in plants are analogous to activities described in humans as autophosphorylation activity takes place from ATP and GTP. In addition to this, plants

TRIM24 (1,301 words) [view diff] exact match in snippet view article find links to article

expression protein catabolic process protein ubiquitination protein autophosphorylation negative regulation of transcription, DNA-templated negative regulation

Neratinib (1,299 words) [view diff] exact match in snippet view article find links to article

and 1.4 μM, respectively. In BT474 cells, neratinib reduces HER2 autophosphorylation, and inhibited cyclin D1 expression while reduced proliferation has

Sporulation in Bacillus subtilis (734 words) [view diff] exact match in snippet view article find links to article

phosphate to the Spo0F Sda Blocks autophosphorylation of KinA KinB Transfers phosphate to the Spo0F KipI Blocks autophosphorylation of KinA Spo0A Activates several

MAP3K3 (1,820 words) [view diff] exact match in snippet view article find links to article

protein phosphorylation positive regulation of p38MAPK cascade protein autophosphorylation blood vessel development phosphorylation positive regulation of I-kappaB

PDGFA (1,108 words) [view diff] exact match in snippet view article find links to article

biosynthetic process angiogenesis positive regulation of protein autophosphorylation positive regulation of ERK1 and ERK2 cascade regulation of smooth

ITK (gene) (1,508 words) [view diff] exact match in snippet view article

response regulation of cell population proliferation peptidyl-tyrosine autophosphorylation T cell receptor signaling pathway T cell activation signal transduction

PDGFC (1,369 words) [view diff] exact match in snippet view article find links to article

population proliferation bone development positive regulation of protein autophosphorylation positive regulation of phosphatidylinositol 3-kinase signaling multicellular

PTPRF (1,451 words) [view diff] exact match in snippet view article find links to article

CA, Dixon JE (1996). "Oncogenic RET receptors display different autophosphorylation sites and substrate binding specificities". J. Biol. Chem. 271 (10):

EPHA8 (783 words) [view diff] exact match in snippet view article find links to article

peptidyl-tyrosine phosphorylation substrate-dependent cell migration protein autophosphorylation axon guidance neuron projection development regulation of cell adhesion

Caveolin 1 (1,555 words) [view diff] exact match in snippet view article find links to article

contraction vesicle organization negative regulation of peptidyl-tyrosine autophosphorylation regulation of cardiac muscle cell action potential involved in regulation

MEX3B (459 words) [view diff] exact match in snippet view article find links to article

component cytoplasm P-body nucleus nucleoplasm cytosol Biological process protein autophosphorylation protein phosphorylation Sources:Amigo / QuickGO

EnvZ/OmpR two-component system (924 words) [view diff] exact match in snippet view article find links to article

follows: Activation of the inner membrane sensor histidine kinase EnvZ, Autophosphorylation of EnvZ at His243, Phosphate transfer to OmpR at Asp 55, Binding

PTK2 (4,724 words) [view diff] exact match in snippet view article find links to article

phosphorylation epidermal growth factor receptor signaling pathway protein autophosphorylation nuclear migration negative regulation of autophagy positive regulation

WNK4 (3,205 words) [view diff] exact match in snippet view article find links to article

EJ (May 2014). "Chloride sensing by WNK1 involves inhibition of autophosphorylation". Science Signaling. 7 (324): ra41. doi:10.1126/scisignal.2005050

Cyclin E1 (1,720 words) [view diff] exact match in snippet view article find links to article

(1996). "Activation of cyclin E/CDK2 is coupled to site-specific autophosphorylation and ubiquitin-dependent degradation of cyclin E." EMBO J. 15 (16):

MAPKAPK2 (1,726 words) [view diff] exact match in snippet view article find links to article

vascular endothelial growth factor stimulus mRNA stabilization protein autophosphorylation 3'-UTR-mediated mRNA stabilization cellular response to DNA damage

CD79A (2,457 words) [view diff] exact match in snippet view article find links to article

Pao L, Sada K, Yamamura H, Cambier JC (Dec 1995). "Role of the Syk autophosphorylation site and SH2 domains in B cell antigen receptor signaling". The Journal

Platycarya strobilacea (202 words) [view diff] exact match in snippet view article find links to article

"Further characterization of galloyl pedunculagin as an effective autophosphorylation inhibitor of C-kinase in vitro". Biological & Pharmaceutical Bulletin

Platelet-derived growth factor receptor A (3,354 words) [view diff] exact match in snippet view article find links to article

Wernstedt C, Claesson-Welsh L, Heldin CH (October 1994). "A unique autophosphorylation site in the platelet-derived growth factor alpha receptor from a

Histidine kinase (2,109 words) [view diff] exact match in snippet view article find links to article

motifs. These motifs include the H, N, G1, F, and G2 boxes. The autophosphorylation H-box is contained in the N-terminal dimerization and histidine phosphotransfer

IRAK3 (708 words) [view diff] exact match in snippet view article find links to article

transduction negative regulation of macrophage cytokine production protein autophosphorylation negative regulation of protein-containing complex disassembly response

Fibroblast growth factor receptor 4 (1,289 words) [view diff] exact match in snippet view article find links to article

ERK1 and ERK2 cascade positive regulation of proteolysis protein autophosphorylation peptidyl-tyrosine phosphorylation cell migration phosphatidylinositol

Fibroblast growth factor receptor 4 (1,289 words) [view diff] exact match in snippet view article find links to article

ERK1 and ERK2 cascade positive regulation of proteolysis protein autophosphorylation peptidyl-tyrosine phosphorylation cell migration phosphatidylinositol

TAOK3 (502 words) [view diff] exact match in snippet view article find links to article

negative regulation of JNK cascade protein phosphorylation protein autophosphorylation mitotic G2 DNA damage checkpoint signaling DNA repair positive regulation

STK25 (665 words) [view diff] exact match in snippet view article find links to article

cell polarity protein phosphorylation Golgi localization protein autophosphorylation response to hydrogen peroxide signal transduction positive regulation

EPHA7 (711 words) [view diff] exact match in snippet view article find links to article

positive regulation of protein phosphorylation regulation of protein autophosphorylation phosphorylation transmembrane receptor protein tyrosine kinase signaling

Histidine kinase (2,109 words) [view diff] exact match in snippet view article find links to article

motifs. These motifs include the H, N, G1, F, and G2 boxes. The autophosphorylation H-box is contained in the N-terminal dimerization and histidine phosphotransfer

EPH receptor B4 (731 words) [view diff] exact match in snippet view article find links to article

development protein phosphorylation cell adhesion angiogenesis protein autophosphorylation peptidyl-tyrosine phosphorylation ephrin receptor signaling pathway

PRKACA (1,681 words) [view diff] exact match in snippet view article find links to article

formation neural tube closure peptidyl-threonine phosphorylation protein autophosphorylation positive regulation of protein export from nucleus sperm capacitation

TNK2 (1,756 words) [view diff] exact match in snippet view article find links to article

regulation of peptidyl-tyrosine phosphorylation peptidyl-tyrosine autophosphorylation regulation of clathrin-dependent endocytosis innate immune response

TGF alpha (2,040 words) [view diff] exact match in snippet view article find links to article

protein-tyrosine kinase. The activity of protein-tyrosine kinase causes an autophosphorylation to occur among several tyrosine residues within EGFR, influencing

TNKS1BP1 (663 words) [view diff] exact match in snippet view article find links to article

peptidyl-threonine phosphorylation positive regulation of protein autophosphorylation positive regulation of peptidyl-serine phosphorylation cellular response

Jeffrey L. Price (1,453 words) [view diff] exact match in snippet view article find links to article

named spaghetti, encoding the SPAG protein. SPAG antagonizes DBT autophosphorylation, increasing the stability of DBT during the day by delaying proteasomal

MAP4K1 (559 words) [view diff] exact match in snippet view article find links to article

membrane intracellular anatomical structure Biological process protein autophosphorylation protein phosphorylation response to stress cell population proliferation

Cyclin-dependent kinase 7 (2,347 words) [view diff] exact match in snippet view article find links to article

EM, Meisenhelder J, Thompson NE, Jones KA (September 2000). "CDK9 autophosphorylation regulates high-affinity binding of the human immunodeficiency virus

Tyrosine kinase 2 (2,850 words) [view diff] exact match in snippet view article find links to article

proliferation type I interferon signaling pathway peptidyl-tyrosine autophosphorylation innate immune response cell migration interleukin-12-mediated signaling

PRKRIR (611 words) [view diff] exact match in snippet view article find links to article

double-stranded RNA-dependent protein kinase, PKR, to regulate its autophosphorylation and activity". J. Biol. Chem. 271 (3): 1702–7. doi:10.1074/jbc.271

MDC1 (3,123 words) [view diff] exact match in snippet view article find links to article

Minter-Dykhouse K, Chen DJ, Chen J (Nov 2004). "MDC1 regulates DNA-PK autophosphorylation in response to DNA damage". J Biol Chem. 279 (45): 46359–62. doi:10

CD135 (1,728 words) [view diff] exact match in snippet view article find links to article

of cell population proliferation lymphocyte proliferation protein autophosphorylation positive regulation of phosphatidylinositol 3-kinase signaling peptidyl-tyrosine

TOM1L1 (582 words) [view diff] exact match in snippet view article find links to article

regulation of mitotic nuclear division positive regulation of protein autophosphorylation protein transport ubiquitin-dependent protein catabolic process via

MOBKL1A (383 words) [view diff] exact match in snippet view article find links to article

nucleus nucleolus cytosol Biological process regulation of protein autophosphorylation hippo signaling positive regulation of phosphorylation positive regulation

Fibroblast growth factor receptor 3 (1,955 words) [view diff] exact match in snippet view article find links to article

proliferation positive regulation of ERK1 and ERK2 cascade protein autophosphorylation peptidyl-tyrosine phosphorylation endochondral bone growth positive

EPH receptor B1 (1,109 words) [view diff] exact match in snippet view article find links to article

regulation of neuron death regulation of ERK1 and ERK2 cascade protein autophosphorylation peptidyl-tyrosine phosphorylation immunological synapse formation

WNK2 (527 words) [view diff] exact match in snippet view article find links to article

Biological process negative regulation of ERK1 and ERK2 cascade protein autophosphorylation protein phosphorylation positive regulation of sodium ion transmembrane

TNIK (628 words) [view diff] exact match in snippet view article find links to article

morphogenesis protein phosphorylation cytoskeleton organization protein autophosphorylation protein localization to plasma membrane regulation of mitotic cell

STK11 (2,646 words) [view diff] exact match in snippet view article find links to article

intrinsic apoptotic signaling pathway by p53 class mediator protein autophosphorylation cell cycle negative regulation of epithelial cell proliferation involved

TAOK1 (753 words) [view diff] exact match in snippet view article find links to article

kinase activity regulation of actin cytoskeleton organization protein autophosphorylation neuron cellular homeostasis regulation of microtubule cytoskeleton

Protein kinase A (2,665 words) [view diff] exact match in snippet view article find links to article

series of phosphorylation events, which can include modification by autophosphorylation and phosphorylation by regulatory kinases, such as PDK1. Thus, PKA

Major vault protein (1,426 words) [view diff] exact match in snippet view article find links to article

pathway negative regulation of signaling negative regulation of protein autophosphorylation neutrophil degranulation transport Sources:Amigo / QuickGO

ASK1 (2,219 words) [view diff] exact match in snippet view article find links to article

but also the NCC, which leads to full activation of ASK1 through autophosphorylation at threonine 845. ASK1 gene transcription can be induced by inflammatory

MINK1 (665 words) [view diff] exact match in snippet view article find links to article

phosphorylation JNK cascade regulation of cell-cell adhesion protein autophosphorylation chemical synaptic transmission regulation of mitotic cell cycle regulation

Endoglin (2,843 words) [view diff] exact match in snippet view article find links to article

of nitric-oxide synthase activity negative regulation of protein autophosphorylation venous blood vessel morphogenesis cell motility positive regulation

PKC alpha (2,643 words) [view diff] exact match in snippet view article find links to article

Ceryak S, Bouscarel B (Aug 2006). "Bile acids stimulate PKCalpha autophosphorylation and activation: role in the attenuation of prostaglandin E1-induced

Nerve growth factor (2,786 words) [view diff] exact match in snippet view article find links to article

drives the homodimerization of the receptor, which in turn causes the autophosphorylation of the tyrosine kinase segment. The tropomyosin receptor kinase A

DOK2 (1,058 words) [view diff] exact match in snippet view article find links to article

PMID 12522270. Jones N, Chen SH, Sturk C, et al. (2003). "A unique autophosphorylation site on Tie2/Tek mediates Dok-R phosphotyrosine binding domain binding

NLRP12 (1,453 words) [view diff] exact match in snippet view article find links to article

regulation of inflammatory response negative regulation of protein autophosphorylation positive regulation of MHC class I biosynthetic process negative

SLA2 (430 words) [view diff] exact match in snippet view article find links to article

signaling pathway cell migration cell differentiation peptidyl-tyrosine autophosphorylation regulation of cell population proliferation innate immune response

CD90 (3,170 words) [view diff] exact match in snippet view article find links to article

signaling pathway positive regulation of GTPase activity protein autophosphorylation negative regulation of protein kinase activity cell adhesion negative

Fibroblast growth factor receptor 2 (1,748 words) [view diff] exact match in snippet view article find links to article

gland morphogenesis regulation of ERK1 and ERK2 cascade protein autophosphorylation mammary gland bud formation pyramidal neuron development lacrimal

Adiponectin (3,593 words) [view diff] exact match in snippet view article find links to article

differentiation response to nutrient negative regulation of protein autophosphorylation negative regulation of intracellular protein transport membrane depolarization

RASSF5 (1,022 words) [view diff] exact match in snippet view article find links to article

Ortiz-Vega S, Avruch J (Jul 2004). "Regulation of the MST1 kinase by autophosphorylation, by the growth inhibitory proteins, RASSF1 and NORE1, and by Ras"

KaiB (2,981 words) [view diff] exact match in snippet view article find links to article

phosphorylation of the Ser431 residue. This interaction drives SasA autophosphorylation and subsequent phosphotransfer to RpaA. Phospho-RpaA activates the

Phosphoglucosamine mutase (345 words) [view diff] exact match in snippet view article find links to article

Pompeo F, van Heijenoort J, Fassy F, Mengin-Lecreulx D (2000). "Autophosphorylation of phosphoglucosamine mutase from Escherichia coli". J. Bacteriol

RAP2A (1,057 words) [view diff] exact match in snippet view article find links to article

epithelial cell apical/basal polarity positive regulation of protein autophosphorylation protein localization to plasma membrane signal transduction Sources:Amigo

Yersinia pseudotuberculosis (3,565 words) [view diff] exact match in snippet view article find links to article

states by expressing GTPase activity. YpkA also catalyses serine autophosphorylation, so it may have regulatory functions in Yersinia or undermine host

Angiotensin-converting enzyme (2,536 words) [view diff] exact match in snippet view article find links to article

proliferation in bone marrow positive regulation of peptidyl-tyrosine autophosphorylation regulation of hematopoietic stem cell proliferation negative regulation

RASSF2 (848 words) [view diff] exact match in snippet view article find links to article

positive regulation of JNK cascade positive regulation of protein autophosphorylation skeletal system development regulation of osteoclast differentiation

RAS p21 protein activator 1 (1,605 words) [view diff] exact match in snippet view article find links to article

Rübsamen-Waigmann H, Strebhardt K (July 1998). "Tyrosine-614, the major autophosphorylation site of the receptor tyrosine kinase HEK2, functions as multi-docking

MST4 (865 words) [view diff] exact match in snippet view article find links to article

hydrogen peroxide-induced cell death protein phosphorylation protein autophosphorylation response to hydrogen peroxide apoptotic process execution phase of

Yersinia pseudotuberculosis (3,565 words) [view diff] exact match in snippet view article find links to article

states by expressing GTPase activity. YpkA also catalyses serine autophosphorylation, so it may have regulatory functions in Yersinia or undermine host

Vascular endothelial growth factor C (3,104 words) [view diff] exact match in snippet view article find links to article

cell migration signal transduction positive regulation of protein autophosphorylation multicellular organism development morphogenesis of embryonic epithelium

NME1-NME2 (206 words) [view diff] exact match in snippet view article find links to article

projection development cellular response to oxidative stress protein autophosphorylation protein complex oligomerization response to growth hormone cellular

STK16 (748 words) [view diff] exact match in snippet view article find links to article

cytoplasm membrane cytoplasm cytosol Biological process protein autophosphorylation peptidyl-tyrosine phosphorylation protein phosphorylation transcription

AAK1 (793 words) [view diff] exact match in snippet view article find links to article

protein stabilization regulation of protein localization protein autophosphorylation positive regulation of Notch signaling pathway protein phosphorylation

Bordetella (2,572 words) [view diff] exact match in snippet view article find links to article

04227.x. PMID 15341649. S2CID 22884606. Uhl M, Miller J (1994). "Autophosphorylation and phosphotransfer in the Bordetella pertussis BvgAS signal transduction

SKAP2 (896 words) [view diff] exact match in snippet view article find links to article

(August 2004). "RAFTK/Pyk2 activation is mediated by trans-acting autophosphorylation in a Src-independent manner". The Journal of Biological Chemistry

MAP4K4 (3,301 words) [view diff] exact match in snippet view article find links to article

phosphorylation for the enzyme to assume full activation and is achieved via autophosphorylation or by upstream kinases. To date, MAP4K4 has been found to be expressed

Aurora kinase A (2,764 words) [view diff] exact match in snippet view article find links to article

meiotic spindle organization mitotic centrosome separation protein autophosphorylation anaphase-promoting complex-dependent catabolic process protein localization

CLK1 (1,132 words) [view diff] exact match in snippet view article find links to article

Cellular component cytoplasm nucleus Biological process protein autophosphorylation peptidyl-tyrosine phosphorylation regulation of RNA splicing protein

PPP2R5E (915 words) [view diff] exact match in snippet view article find links to article

transduction regulation of phosphoprotein phosphatase activity regulation of protein autophosphorylation protein dephosphorylation Sources:Amigo / QuickGO

STK39 (605 words) [view diff] exact match in snippet view article find links to article

protein phosphorylation peptidyl-serine phosphorylation protein autophosphorylation ion homeostasis positive regulation of T cell chemotaxis chemokine

RIPK1 (4,148 words) [view diff] exact match in snippet view article find links to article

phosphorylation regulation of ATP:ADP antiporter activity peptidyl-serine autophosphorylation regulation of tumor necrosis factor-mediated signaling pathway positive

PIM1 (2,973 words) [view diff] exact match in snippet view article find links to article

development protein phosphorylation hyaluronan metabolic process protein autophosphorylation cell cycle cell population proliferation vitamin D receptor signaling

Insulin (13,804 words) [view diff] exact match in snippet view article find links to article

is triggered by the insulin binding. This activity provokes the autophosphorylation of the β subunits and subsequently the phosphorylation of proteins

CDKL5 (2,565 words) [view diff] exact match in snippet view article find links to article

GTPase activity positive regulation of dendrite morphogenesis protein autophosphorylation positive regulation of axon extension regulation of dendrite development

TRIM28 (2,254 words) [view diff] exact match in snippet view article find links to article

protein phosphorylation protein complex oligomerization protein autophosphorylation DNA methylation involved in embryo development Ras protein signal

GRAP (621 words) [view diff] exact match in snippet view article find links to article

signaling pathway cell migration cell differentiation peptidyl-tyrosine autophosphorylation regulation of cell population proliferation innate immune response

Pseudokinase (1,374 words) [view diff] exact match in snippet view article find links to article

"ErbB3/HER3 intracellular domain is competent to bind ATP and catalyze autophosphorylation". Proceedings of the National Academy of Sciences of the United States

Restriction point (2,729 words) [view diff] exact match in snippet view article find links to article

(RTK) triggers a conformational change and promotes dimerization and autophosphorylation of tyrosine residues on the cytoplasmic tail of the RTKs. These phosphorylated

PPP2R5B (1,109 words) [view diff] exact match in snippet view article find links to article

complex cytoplasm nucleus Biological process regulation of protein autophosphorylation positive regulation of DNA-binding transcription factor activity

MRE11A (2,146 words) [view diff] exact match in snippet view article find links to article

repair via homologous recombination positive regulation of protein autophosphorylation cell population proliferation mitotic G2 DNA damage checkpoint signaling

Glycogen synthase kinase-3 beta (1,777 words) [view diff] exact match in snippet view article find links to article

export from nucleus positive regulation of GTPase activity protein autophosphorylation cell differentiation negative regulation of protein localization

ICK (gene) (606 words) [view diff] exact match in snippet view article

kinase within a mitogen-activated protein kinase-like TDY motif by autophosphorylation and cyclin-dependent protein kinase-activating kinase". Mol. Cell

PPP2R5A (1,286 words) [view diff] exact match in snippet view article find links to article

membrane protein dephosphorylation regulation of phosphoprotein phosphatase activity regulation of protein autophosphorylation Sources:Amigo / QuickGO

Liprin-alpha-1 (1,160 words) [view diff] exact match in snippet view article find links to article

"Liprin phosphorylation regulates binding to LAR: evidence for liprin autophosphorylation". Biochemistry. 44 (48): 15715–15724. doi:10.1021/bi051434f. PMC 2529169

CLK3 (gene) (664 words) [view diff] exact match in snippet view article

phosphorylation protein phosphorylation regulation of RNA splicing protein autophosphorylation peptidyl-tyrosine phosphorylation Sources:Amigo / QuickGO

NEK2 (1,182 words) [view diff] exact match in snippet view article find links to article

centrosome separation mitotic sister chromatid segregation protein autophosphorylation cell cycle negative regulation of centriole-centriole cohesion regulation

GRAP2 (1,459 words) [view diff] exact match in snippet view article find links to article

signaling pathway cell migration cell differentiation peptidyl-tyrosine autophosphorylation regulation of cell population proliferation innate immune response

PPP2R5D (1,090 words) [view diff] exact match in snippet view article find links to article

phosphoprotein phosphatase activity negative regulation of peptidyl-threonine phosphorylation regulation of protein autophosphorylation Sources:Amigo / QuickGO

SNX8 (4,216 words) [view diff] exact match in snippet view article find links to article

JAK1-SNX8-IKKβ complex. This linkage is essential for IKKβ activation through autophosphorylation at serine in position 177 (as SNX8 lacks enzymatic activity) and

RAP2B (818 words) [view diff] exact match in snippet view article find links to article

negative regulation of cell migration positive regulation of protein autophosphorylation platelet aggregation signal transduction neutrophil degranulation

PRKX (445 words) [view diff] exact match in snippet view article find links to article

endothelial cell proliferation kidney morphogenesis angiogenesis protein autophosphorylation endothelial cell migration regulation of epithelial cell differentiation

ERRFI1 (932 words) [view diff] exact match in snippet view article find links to article

signaling pathway skin morphogenesis negative regulation of protein autophosphorylation cellular response to platelet-derived growth factor stimulus cellular

PPP2R5C (1,291 words) [view diff] exact match in snippet view article find links to article

regulation of phosphoprotein phosphatase activity regulation of protein autophosphorylation protein dephosphorylation negative regulation of protein kinase B

RIPK3 (952 words) [view diff] exact match in snippet view article find links to article

transcription factor activity apoptotic signaling pathway protein autophosphorylation positive regulation of ligase activity necroptosis regulation of

Cyclin T1 (1,358 words) [view diff] exact match in snippet view article find links to article

EM, Meisenhelder J, Thompson NE, Jones KA (September 2000). "CDK9 autophosphorylation regulates high-affinity binding of the human immunodeficiency virus

AKT1 (2,850 words) [view diff] exact match in snippet view article find links to article

insulin stimulus cellular response to decreased oxygen levels protein autophosphorylation inflammatory response positive regulation of fat cell differentiation

Rad50 (2,139 words) [view diff] exact match in snippet view article find links to article

meiosis double-strand break repair positive regulation of protein autophosphorylation cell cycle viral process double-strand break repair via nonhomologous

NME2 (1,265 words) [view diff] exact match in snippet view article find links to article

projection development cellular response to oxidative stress protein autophosphorylation protein complex oligomerization response to growth hormone cellular

Flagellum (7,055 words) [view diff] exact match in snippet view article find links to article

der Does, Chris; Hugel, Thorsten; Albers, Sonja-Verena (2021). "Autophosphorylation of the KaiC-like protein ArlH inhibits oligomerization and interaction

SUPT5H (1,231 words) [view diff] exact match in snippet view article find links to article

Suess EM, Meisenhelder J, Thompson NE, Jones KA (Sep 2000). "CDK9 autophosphorylation regulates high-affinity binding of the human immunodeficiency virus

LRRK2 (1,929 words) [view diff] exact match in snippet view article find links to article

receptor signaling pathway regulation of membrane potential protein autophosphorylation regulation of mitochondrial fission regulation of neuron maturation

Angiogenesis (5,763 words) [view diff] exact match in snippet view article find links to article

single-chain receptor tyrosine kinases that become activated through autophosphorylation induced by a mechanism of FGF-mediated receptor dimerization. Receptor

NEK6 (1,164 words) [view diff] exact match in snippet view article find links to article

positive regulation of I-kappaB kinase/NF-kappaB signaling protein autophosphorylation regulation of cellular senescence cell cycle apoptotic process signal

Calcineurin B homologous protein 1 (929 words) [view diff] exact match in snippet view article find links to article

cascade hyaluronan catabolic process negative regulation of protein autophosphorylation negative regulation of protein kinase activity positive regulation

NLK (1,049 words) [view diff] exact match in snippet view article find links to article

signaling pathway transcription, DNA-templated MAPK cascade protein autophosphorylation transforming growth factor beta receptor signaling pathway Wnt signaling

SLK (gene) (969 words) [view diff] exact match in snippet view article

microtubule organization regulation of focal adhesion assembly protein autophosphorylation apoptotic process regulation of cell migration regulation of apoptotic

PRKAR2B (1,406 words) [view diff] exact match in snippet view article find links to article

Merlo G, Clair T, Cho-Chung YS (Nov 1995). "Point mutation of the autophosphorylation site or in the nuclear location signal causes protein kinase A RII

KIT (gene) (4,118 words) [view diff] exact match in snippet view article

differentiation negative regulation of programmed cell death protein autophosphorylation mast cell degranulation inflammatory response positive regulation

CALM2 (1,228 words) [view diff] exact match in snippet view article find links to article

signaling substantia nigra development positive regulation of protein autophosphorylation regulation of cytokinesis positive regulation of phosphoprotein phosphatase

UHMK1 (1,122 words) [view diff] exact match in snippet view article find links to article

protein phosphorylation peptidyl-serine phosphorylation protein autophosphorylation neuron projection development positive regulation of translational

Akt/PKB signaling pathway (4,116 words) [view diff] exact match in snippet view article find links to article

phosphorylation is not fully understood but may also be influenced by autophosphorylation after Thr308 phosphorylation. After stimulation, the levels of PIP3

ROS1 (3,680 words) [view diff] exact match in snippet view article find links to article

spermatogenesis regulation of ERK1 and ERK2 cascade peptidyl-tyrosine autophosphorylation cell population proliferation columnar/cuboidal epithelial cell development

GDNF family of ligands (1,125 words) [view diff] exact match in snippet view article find links to article

complex then brings together two molecules of RET, triggering trans-autophosphorylation of specific tyrosine residues within the tyrosine kinase domain of

Interferon (7,054 words) [view diff] exact match in snippet view article find links to article

Envelope Protein E2 Does Not Inhibit PKR by Simple Competition with Autophosphorylation Sites in the RNA-Binding Domain". Journal of Virology. 75 (3): 1265–1273

Nerve injury (4,113 words) [view diff] exact match in snippet view article find links to article

tyrosine kinase receptors; binding to the specific receptor yields autophosphorylation and subsequent phosphorylation of tyrosine residues on proteins that

Neuregulin 1 (3,921 words) [view diff] exact match in snippet view article find links to article

ERBB4 signaling pathway positive regulation of peptidyl-tyrosine autophosphorylation myelination in peripheral nervous system intracellular signal transduction

Tropomyosin receptor kinase B (4,321 words) [view diff] exact match in snippet view article find links to article

transmembrane receptor protein tyrosine kinase signaling pathway protein autophosphorylation trans-synaptic signaling by neuropeptide, modulating synaptic transmission

Paracrine signaling (4,940 words) [view diff] exact match in snippet view article find links to article

transmembrane receptor to another RTK receptor, which causes the autophosphorylation and subsequent conformational change of the homodimerized receptor

Mitogen-activated protein kinase (5,501 words) [view diff] exact match in snippet view article find links to article

through induced N-C dissociation and dimerization-mediated trans autophosphorylation of the MTK1 kinase domain". Molecular and Cellular Biology. 27 (7):

MAK (gene) (640 words) [view diff] exact match in snippet view article

organism development protein phosphorylation spermatogenesis protein autophosphorylation regulation of gene expression intracellular signal transduction intraciliary

Substrate presentation (1,873 words) [view diff] exact match in snippet view article find links to article

cholesterol within lipid rafts. Once dimerized, the receptor undergoes autophosphorylation, which triggers a subsequent phosphorylation cascade. This is a specific

Alok Bhattacharya (2,119 words) [view diff] exact match in snippet view article find links to article

Mansuri; Mrigya Babuta; Sabir Ali; Alok Bhattacharya (January 2016). "Autophosphorylation at Thr279 of Entamoeba histolytica atypical kinase EhAK1 is required

Chromium in glucose metabolism (1,597 words) [view diff] exact match in snippet view article find links to article

and induces a conformational change. This change results in the autophosphorylation of the tyrosine residue located on the internal ß-subunit of the

ULK1 (1,926 words) [view diff] exact match in snippet view article find links to article

to nutrient levels axon extension response to starvation protein autophosphorylation neuron projection development signal transduction autophagy macroautophagy

Martin J. Lohse (1,109 words) [view diff] exact match in snippet view article find links to article

Eva M; Lohse, Martin J (7 December 2008). "A new type of ERK1/2 autophosphorylation causes cardiac hypertrophy". Nature Medicine. 15 (1). Springer Science

Cyclin H (1,468 words) [view diff] exact match in snippet view article find links to article

Suess EM, Meisenhelder J, Thompson NE, Jones KA (Sep 2000). "CDK9 autophosphorylation regulates high-affinity binding of the human immunodeficiency virus

Aurora kinase B (4,529 words) [view diff] exact match in snippet view article find links to article

checkpoint signaling positive regulation of telomerase activity protein autophosphorylation negative regulation of B cell apoptotic process negative regulation

Transcription factor Jun (5,496 words) [view diff] exact match in snippet view article find links to article

transcription by RNA polymerase II negative regulation of protein autophosphorylation membrane depolarization negative regulation of apoptotic process

Fibroblast growth factor receptor 1 (5,001 words) [view diff] exact match in snippet view article find links to article

morphogenesis positive regulation of neuron differentiation protein autophosphorylation auditory receptor cell development positive regulation of MAPK cascade

Nibrin (2,607 words) [view diff] exact match in snippet view article find links to article

capping DNA duplex unwinding meiosis positive regulation of protein autophosphorylation isotype switching cell cycle blastocyst growth cell population proliferation

Calmodulin 1 (1,681 words) [view diff] exact match in snippet view article find links to article

peptidyl-threonine phosphorylation positive regulation of protein autophosphorylation regulation of cardiac muscle contraction regulation of cell communication

Cyclin-dependent kinase 5 (5,356 words) [view diff] exact match in snippet view article find links to article

potential excitatory postsynaptic potential synapse assembly protein autophosphorylation positive regulation of actin cytoskeleton reorganization negative

BUB1B (2,313 words) [view diff] exact match in snippet view article find links to article

C, Ahmad S, Zhang J, Mao Y (July 2012). "CENP-E--dependent BubR1 autophosphorylation enhances chromosome alignment and the mitotic checkpoint". The Journal

Chemotaxis (7,290 words) [view diff] exact match in snippet view article find links to article

bind to the receptor. The absence of receptor activation results in autophosphorylation in the histidine kinase, CheA, at a single highly conserved histidine

Phosphoinositide-dependent kinase-1 (2,127 words) [view diff] exact match in snippet view article find links to article

endothelial cell migration cellular response to insulin stimulus protein autophosphorylation regulation of mast cell degranulation peptidyl-threonine phosphorylation

Richard Ulevitch (315 words) [view diff] exact match in snippet view article find links to article

kinase-independent activation of p38a mediated by TAB 1-dependent autophosphorylation of p38a. Science 295:1291-1294, 2002. "Department of Immunology and

VRK1 (863 words) [view diff] exact match in snippet view article find links to article

membrane reassembly Golgi disassembly regulation of cell shape protein autophosphorylation peptidyl-serine phosphorylation peptidyl-threonine phosphorylation

G protein-coupled receptor (9,376 words) [view diff] exact match in snippet view article find links to article

which has unique ability to increase its binding affinity to CaM by autophosphorylation, making CaM unavailable for the activation of other enzymes. The

TAF1 (2,422 words) [view diff] exact match in snippet view article find links to article

phosphorylation DNA-templated transcription, initiation protein autophosphorylation cell cycle transcription initiation from RNA polymerase II promoter

Interferon gamma (6,477 words) [view diff] exact match in snippet view article find links to article

IFNGR1 and IFNGR2 undergo conformational changes that result in the autophosphorylation and activation of JAK1 and JAK2. This leads to a signaling cascade

SMG1 (1,212 words) [view diff] exact match in snippet view article find links to article

biosynthetic process cellular response to DNA damage stimulus protein autophosphorylation phosphorylation regulation of telomere maintenance DNA repair regulation

CALM3 (1,606 words) [view diff] exact match in snippet view article find links to article

peptidyl-threonine phosphorylation positive regulation of protein autophosphorylation regulation of cardiac muscle contraction regulation of cell communication

GPNMB (2,138 words) [view diff] exact match in snippet view article find links to article

positive regulation of cell migration positive regulation of protein autophosphorylation regulation of tissue remodeling negative regulation of T cell proliferation

CSNK1D (14,738 words) [view diff] exact match in snippet view article find links to article

significant. These differences can be explained by various degrees of autophosphorylation of the transcription variants. Based on software analysis of the

WNK3 (927 words) [view diff] exact match in snippet view article find links to article

phosphorylation positive regulation of sodium ion transport protein autophosphorylation positive regulation of sodium ion transmembrane transporter activity

P110δ (2,559 words) [view diff] exact match in snippet view article find links to article

M, Anderson S, Brennan P, Ward SG, Waterfield MD (March 1999). "Autophosphorylation of p110delta phosphoinositide 3-kinase: a new paradigm for the regulation

PINK1 (2,677 words) [view diff] exact match in snippet view article find links to article

dephosphorylation ubiquitin-dependent protein catabolic process peptidyl-serine autophosphorylation regulation of neuron apoptotic process response to oxidative stress

DNA-PKcs (3,785 words) [view diff] exact match in snippet view article find links to article

been identified as substrates for the kinase activity of DNA-PK. Autophosphorylation of DNA-PKcs appears to play a key role in NHEJ and is thought to

Archaellum (3,642 words) [view diff] exact match in snippet view article find links to article

J, Chaudhury P, Kumariya R, van der Does C, et al. (July 2021). "Autophosphorylation of the KaiC-like protein ArlH inhibits oligomerisation and interaction

Adapter molecule crk (2,941 words) [view diff] exact match in snippet view article find links to article

PMID 2173144. Schaller MD, Hildebrand JD, Shannon JD, et al. (1994). "Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding

Interleukin-1 receptor associated kinase (3,637 words) [view diff] exact match in snippet view article find links to article

and IRAK-4, allowing IRAK-4 to phosphorylate IRAK-1, leading to autophosphorylation and activation of IRAK-1 [1,2]. IRAK-4 is critical for IL-1R and

DNA repair (15,713 words) [view diff] exact match in snippet view article find links to article

(January 2003). "DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation". Nature. 421 (6922): 499–506. Bibcode:2003Natur

Ataxia–telangiectasia (10,515 words) [view diff] exact match in snippet view article find links to article

(January 2003). "DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation". Nature. 421 (6922): 499–506. Bibcode:2003Natur

Nucleotide pyrophosphatase/phosphodiesterase (1,857 words) [view diff] exact match in snippet view article find links to article

Mercuri, Francesca A.; Sali, Adnan; Goding, James W. (1995-03-01). "Autophosphorylation of PC-1 (Alkaline Phosphodiesterase I/Nucleotide Pyrophosphatase)

CSNK2B (2,258 words) [view diff] exact match in snippet view article find links to article

subunit of casein kinase II in human A431 cells. Identification of the autophosphorylation site and a site phosphorylated by p34cdc2". J. Biol. Chem. 266 (30):

MTOR (12,710 words) [view diff] exact match in snippet view article find links to article

regulation of peptidyl-tyrosine phosphorylation social behavior protein autophosphorylation negative regulation of cholangiocyte apoptotic process regulation

Gcn2 (2,065 words) [view diff] exact match in snippet view article find links to article

results from a conformation that facilitates ATP binding, leading to autophosphorylation of an activation loop which leads to maximal GCN2 kinase activity

Alexei Kharitonenkov (2,468 words) [view diff] exact match in snippet view article find links to article

PMID 2481508. Kharitonenkov, A. I.; Bulargina, T. V. (1991-02-01). "[Autophosphorylation of EGF receptors in the A431 cell line with an increased intracellular

Autoinducer (3,901 words) [view diff] exact match in snippet view article find links to article

has reached a threshold concentration. Detection is followed by autophosphorylation of ComD, which in turn, phosphorylates ComE. ComE is a response regulator

RIOK1 (1,377 words) [view diff] exact match in snippet view article find links to article

Examples: P62166, O14776. The mutation (D324A) in RIOK1 abolishes autophosphorylation activity, enhances association with pre-40S ribosomal subunits and

Denise Manahan-Vaughan (2,728 words) [view diff] exact match in snippet view article find links to article

PMID 26042007. Goh J, Manahan-Vaughan D (May 2015). "Role of inhibitory autophosphorylation of calcium/calmodulin-dependent kinase II (αCAMKII) in persistent

IQGAP1 (3,922 words) [view diff] exact match in snippet view article find links to article

focal adhesion assembly positive regulation of peptidyl-tyrosine autophosphorylation positive regulation of GTPase activity positive regulation of protein

GRB2 (9,365 words) [view diff] exact match in snippet view article find links to article

organization cell migration cell differentiation peptidyl-tyrosine autophosphorylation regulation of cell population proliferation innate immune response

SULF1 (6,569 words) [view diff] exact match in snippet view article find links to article

Receptor (FGFR) to cause receptor dimerization, activation, and autophosphorylation, which then leads to induction of the mitogen-activated protein kinase

Double-strand break repair model (4,127 words) [view diff] exact match in snippet view article find links to article

Morotomi-Yano K, Jakob B, Taucher-Scholz G, et al. (April 2007). "Autophosphorylation of DNA-PKCS regulates its dynamics at DNA double-strand breaks".

Alcino J. Silva (6,318 words) [view diff] exact match in snippet view article find links to article

Giese, K.P.; Fedorov, N.B.; Filipkowski, R.K.; Silva, A.J. (1998). "Autophosphorylation at Thr286 of the alpha calcium-calmodulin kinase II in LTP and learning"

Molecular and epigenetic mechanisms of alcoholism (6,687 words) [view diff] exact match in snippet view article find links to article

receptors whose subsequent activation results in dimerization and autophosphorylation of the receptor. In its phosphorylated form, TrkB receptors recruit

Mastocytoma in dogs (5,640 words) [view diff] exact match in snippet view article find links to article

481–493, ISSN 1944-7930. PMID 22204765. Y. Takeuchi et al.: Aberrant autophosphorylation of c-Kit receptor in canine mast cell tumor cell lines. In: Veterinary