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searching for PAK1 39 found (64 total)

alternate case: pAK1

PAK2 (2,256 words) [view diff] exact match in snippet view article find links to article

long polypeptide and a 1.2-kb long non-coding RNA transcript. Similar to PAK1, PAK2 contains a p21-binding domain (PBD) and an auto-inhibitory domain (AID)

PAK4 (3,029 words) [view diff] exact match in snippet view article find links to article

the PAK family of serine/threonine kinases which are divided into group I (PAK1, PAK2 and PAK3) and group II (PAK4, PAK6 and PAK5/7). PAK4 localizes in sub-cellular

GIT1 (1,286 words) [view diff] exact match in snippet view article find links to article

spine morphology and formation—this is thought to occur through the Rac1/PAK1/LIMK/CFL1 pathway. GIT1 has been shown to interact with: ARHGEF7, Beta adrenergic

Lim kinase (2,692 words) [view diff] case mismatch in snippet view article find links to article

through small GTPases of the Rho family. Upstream, LIMK1 is regulated by Pak1, and LIMK2 by the Rho-dependent kinase ROCK. Lim Kinases are activated by

Autophosphorylation (2,321 words) [view diff] exact match in snippet view article find links to article

IGF1R Tyr1165 site) Ser/Thr phosphorylation sites in activation loops: human PAK1, Thr423 (PDB: 3Q4Z, 4O0R, 4O0T, 4P90, 4ZLO, 4ZY4, 4ZY5, 4ZY6, 5DEY; the 4ZY4

Neurite (1,428 words) [view diff] case mismatch in snippet view article find links to article

(2013-03-18). "Conversion of a signal into forces for axon outgrowth through Pak1-mediated shootin1 phosphorylation". Current Biology. 23 (6): 529–534. Bibcode:2013CBio

Prisca Liberali (875 words) [view diff] case mismatch in snippet view article find links to article

and symmetry breaking in intestinal organoid development The closure of Pak1-dependent macropinosomes requires the phosphorylation of CtBP1/BARS Liberali

Mir-7 microRNA precursor (1,373 words) [view diff] case mismatch in snippet view article find links to article

insulin-like growth factor 1 receptor (IGF1R) and PIK3CD, E(spl) gene family and Pak1 (cancer cells). c-Fos is also a target of miR-7b in mice. Pax6 translation

Coldharbour, Greenwich (1,015 words) [view diff] case mismatch in snippet view article find links to article

%26_phstart%3DsuccessSource&treeid=&personid=&hintid=&usePUB=true&_phsrc=PaK1&_phstart=successSource&usePUBJs=true [user-generated source] The Kentish

NET1 (541 words) [view diff] exact match in snippet view article find links to article

M412141200. PMID 15611121. Alberts AS, Qin H, Carr HS, Frost JA (2005). "PAK1 negatively regulates the activity of the Rho exchange factor NET1". J. Biol

ACTG2 (1,017 words) [view diff] exact match in snippet view article find links to article

Type 1 Tat Regulates Endothelial Cell Actin Cytoskeletal Dynamics through PAK1 Activation and Oxidant Production". J. Virol. 78 (2): 779–89. doi:10.1128/JVI

Protein kinase N1 (1,759 words) [view diff] exact match in snippet view article find links to article

L, Baer M, Trejo J, Coughlin S, Chant J (1996). "Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway". Curr. Biol. 6 (5): 598–605

Barry James Thompson (1,798 words) [view diff] case mismatch in snippet view article find links to article

but Cdc42 appears to act primarily via activating the kinases aPKC and Pak1 in Drosophila follicle cells. His laboratory also discovered that planar

FOXL2 (2,264 words) [view diff] case mismatch in snippet view article find links to article

PMID 12529855. Mazumdar A, Kumar R (January 2003). "Estrogen regulation of Pak1 and FKHR pathways in breast cancer cells". FEBS Letters. 535 (1–3): 6–10

GIT2 (1,089 words) [view diff] exact match in snippet view article find links to article

PMID 10942595. Ku GM, Yablonski D, Manser E, Lim L, Weiss A (Feb 2001). "A PAK1-PIX-PKL complex is activated by the T-cell receptor independent of Nck, Slp-76

Protein design (7,685 words) [view diff] exact match in snippet view article find links to article

including TNT. More recently, Kuhlman and coworkers designed a biosensor of the PAK1. In a sense, protein design is a subset of battery design.[further explanation

SPEN (855 words) [view diff] case mismatch in snippet view article find links to article

Vadlamudi RK, Manavathi B, Singh RR, et al. (2005). "An essential role of Pak1 phosphorylation of SHARP in Notch signaling". Oncogene. 24 (28): 4591–6.

HGS (gene) (1,399 words) [view diff] case mismatch in snippet view article

for cytokine-mediated c-fos induction through interaction with TAK1 and Pak1". J. Biol. Chem. 276 (32): 29943–52. doi:10.1074/jbc.M104230200. PMID 11397816

Han Jiahuai (394 words) [view diff] case mismatch in snippet view article find links to article

Regulate p38 Mitogen-activated Protein Kinase through the Downstream Mediator Pak1". Journal of Biological Chemistry. 270 (41): 23934–23936. doi:10.1074/jbc

MAP2K1IP1 (1,022 words) [view diff] exact match in snippet view article find links to article

"The MEK1 scaffolding protein MP1 regulates cell spreading by integrating PAK1 and Rho signals". Mol. Cell. Biol. 25 (12): 5119–33. doi:10.1128/MCB.25.12

ARHGDIA (1,302 words) [view diff] case mismatch in snippet view article find links to article

DerMardirossian C, Schnelzer A, Bokoch GM (2004). "Phosphorylation of RhoGDI by Pak1 mediates dissociation of Rac GTPase". Mol. Cell. 15 (1): 117–27. doi:10.1016/j

25B-NBOMe (3,023 words) [view diff] exact match in snippet view article find links to article

substances downregulated expression level of p21 (CDC24/RAC)-activated kinase 1 (PAK1), an enzyme with documented cardiac protective effects. Preliminary studies

CDK5R1 (1,381 words) [view diff] case mismatch in snippet view article find links to article

PMID 11583627. Rashid T, Banerjee M, Nikolic M (2002). "Phosphorylation of Pak1 by the p35/Cdk5 kinase affects neuronal morphology". J. Biol. Chem. 276 (52):

25iP-NBOMe (1,767 words) [view diff] exact match in snippet view article find links to article

substances downregulated expression level of p21 (CDC24/RAC)-activated kinase 1 (PAK1), an enzyme with documented cardiac protective effects. Preliminary studies

25N-NBOMe (2,167 words) [view diff] exact match in snippet view article find links to article

substances downregulated expression level of p21 (CDC24/RAC)-activated kinase 1 (PAK1), an enzyme with documented cardiac protective effects. Preliminary studies

25D-NBOMe (2,183 words) [view diff] exact match in snippet view article find links to article

substances downregulated expression level of p21 (CDC24/RAC)-activated kinase 1 (PAK1), an enzyme with documented cardiac protective effects. Preliminary studies

25G-NBOMe (1,906 words) [view diff] exact match in snippet view article find links to article

substances downregulated expression level of p21 (CDC24/RAC)-activated kinase 1 (PAK1), an enzyme with documented cardiac protective effects. Preliminary studies

CDC42BPA (954 words) [view diff] case mismatch in snippet view article find links to article

DC, Sanders LC, Bokoch GM, Gill GN (1999). "Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics". Nat

CDC42BPA (954 words) [view diff] case mismatch in snippet view article find links to article

DC, Sanders LC, Bokoch GM, Gill GN (1999). "Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics". Nat

25C-NBOMe (2,913 words) [view diff] exact match in snippet view article find links to article

substances downregulated expression level of p21 (CDC24/RAC)-activated kinase 1 (PAK1), an enzyme with documented cardiac protective effects. Preliminary studies

PGM1 (2,065 words) [view diff] case mismatch in snippet view article find links to article

Ser108 as part of its catalytic mechanism. This is shown to be performed by Pak1, a previously identified signaling kinase. Phosphoglucomutase 1 (PGM1) deficiency

25H-NBOMe (1,935 words) [view diff] exact match in snippet view article find links to article

substances downregulated expression level of p21 (CDC24/RAC)-activated kinase 1 (PAK1), an enzyme with documented cardiac protective effects. Preliminary studies

Dendritic spine (5,682 words) [view diff] case mismatch in snippet view article find links to article

administration of the Cdc42 binding domain of Wasp or inhibitor targeting Pak1 activation-3 (IPA3) decreases this sustained growth in volume, demonstrating

Madin-Darby canine kidney cells (2,658 words) [view diff] case mismatch in snippet view article find links to article

Retrieved 2017-09-28 – via YouTube. Hunter MP, Zegers MM (July 2010). "Pak1 regulates branching morphogenesis in 3D MDCK cell culture by a PIX and

HIST1H4A (689 words) [view diff] exact match in snippet view article find links to article

PMID 14657027. Phee H, Abraham RT, Weiss A (2005). "Dynamic recruitment of PAK1 to the immunological synapse is mediated by PIX independently of SLP-76 and

Azeliragon (458 words) [view diff] exact match in snippet view article find links to article

Hu, Chunping; Sun, Xiaoyan; Cao, Peng (June 2023). "Azeliragon inhibits PAK1 and enhances the therapeutic efficacy of AKT inhibitors in pancreatic cancer"

25I-NBOMe (5,448 words) [view diff] exact match in snippet view article find links to article

substances downregulated expression level of p21 (CDC24/RAC)-activated kinase 1 (PAK1), an enzyme with documented cardiac protective effects. Preliminary studies

25-NB (2,960 words) [view diff] exact match in snippet view article find links to article

substances downregulated expression level of p21 (CDC24/RAC)-activated kinase 1 (PAK1), an enzyme with documented cardiac protective effects. Preliminary studies

P14 deficiency (2,488 words) [view diff] exact match in snippet view article find links to article

"The MEK1 Scaffolding Protein MP1 Regulates Cell Spreading by Integrating PAK1 and Rho Signals". Molecular and Cellular Biology. 25 (12): 5119–5133. doi:10