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searching for Gene product 524 found (1150 total)

alternate case: gene product

Nef (protein) (1,133 words) [view diff] no match in snippet view article

Nef (Negative Regulatory Factor) is a small 27-35 kDa myristoylated protein encoded by primate lentiviruses. These include Human Immunodeficiency Viruses
HES7 gene (2,159 words) [view diff] exact match in snippet view article find links to article
and Enhancer of Split families of Basic helix-loop-helix proteins. The gene product is a transcription factor and is expressed cyclically in the presomitic
B3GAT3 (701 words) [view diff] exact match in snippet view article find links to article
recognizing nonreducing terminal sugars and their anomeric linkages. This gene product catalyzes the formation of the glycosaminoglycan-protein linkage by way
GPR12 (346 words) [view diff] exact match in snippet view article find links to article
receptor 12 is a protein that in humans is encoded by the GPR12 gene. The gene product of GPR12 is an orphan receptor, meaning that its endogenous ligand is
Zebrafish Information Network (475 words) [view diff] exact match in snippet view article find links to article
sequence databases (e.g., GenBank) and to genome browsers are included. Gene product, gene expression, and phenotype data are annotated with terms from biomedical
Allele (1,887 words) [view diff] exact match in snippet view article find links to article
alleles observed result in little or no change in the function of the gene product it codes for. However, sometimes different alleles can result in different
Haploinsufficiency (1,184 words) [view diff] exact match in snippet view article find links to article
loss-of-function mutation in the variant allele, such that it yields little or no gene product (often a protein). Although the other, standard allele still produces
Gene nomenclature (4,153 words) [view diff] exact match in snippet view article find links to article
nomenclature, because it aims to unify the representation of gene and gene product attributes across all species. Gene nomenclature and protein nomenclature
ZNF41 (540 words) [view diff] exact match in snippet view article find links to article
protein 41 is a protein that in humans is encoded by the ZNF41 gene. This gene product is a likely zinc finger family transcription factor. It contains KRAB-A
SGK2 (562 words) [view diff] exact match in snippet view article find links to article
This gene encodes a serine/threonine protein kinase. Although this gene product is similar to serum- and glucocorticoid-induced protein kinase (SGK)
40S ribosomal protein S18 (693 words) [view diff] exact match in snippet view article find links to article
S13P family of ribosomal proteins. It is located in the cytoplasm. The gene product of the E. coli ortholog (ribosomal protein S13) is involved in the binding
40S ribosomal protein S11 (721 words) [view diff] exact match in snippet view article find links to article
S17P family of ribosomal proteins. It is located in the cytoplasm. The gene product of the E. coli ortholog (ribosomal protein S17) is thought to be involved
FlyBase (2,070 words) [view diff] exact match in snippet view article find links to article
insertions, sequence-level gene models, and molecular classification of gene product functions. Query tools allow navigation of FlyBase through DNA or protein
Bloom syndrome protein (2,565 words) [view diff] exact match in snippet view article find links to article
BLM gene and is not expressed in Bloom syndrome. The Bloom syndrome gene product is related to the RecQ subset of DExH box-containing DNA helicases and
P2RY11 (597 words) [view diff] exact match in snippet view article find links to article
and encodes a fusion protein that shares identity with each individual gene product. P2Y receptor GRCh38: Ensembl release 89: ENSG00000244165 – Ensembl,
HLA-B73 (288 words) [view diff] exact match in snippet view article find links to article
HLA-B73 (B73) is an HLA-B serotype. The serotype identifies the HLA-B*7301 gene product. Part of B*7301 is similar to the HLA-B22 family, however part resembles
DYRK3 (464 words) [view diff] exact match in snippet view article find links to article
kinase 3 is an enzyme that in humans is encoded by the DYRK3 gene. This gene product belongs to the DYRK family of dual-specificity protein kinases that catalyze
Gene-for-gene relationship (1,975 words) [view diff] exact match in snippet view article find links to article
Plants producing a specific R gene product are resistant towards a pathogen that produces the corresponding Avr gene product. Gene-for-gene relationships
CD82 (gene) (1,382 words) [view diff] exact match in snippet view article
a human protein encoded by the CD82 gene. This metastasis suppressor gene product is a membrane glycoprotein that is a member of the tetraspanin/transmembrane
PDGFD (793 words) [view diff] exact match in snippet view article find links to article
motif of eight cysteines, seven of which are found in this factor. This gene product only forms homodimers and, therefore, does not dimerize with the other
DUSP12 (556 words) [view diff] exact match in snippet view article find links to article
modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine
Bacterial transcription (2,369 words) [view diff] exact match in snippet view article find links to article
a series of genes that work together to code for the same protein or gene product and are controlled by a single promoter. Bacterial RNA polymerase is
Collagen, type VIII, alpha 1 (763 words) [view diff] exact match in snippet view article find links to article
gene encodes one of the two alpha chains of type VIII collagen. The gene product is a short chain collagen and a major component of the basement membrane
Asparagine endopeptidase (1,932 words) [view diff] exact match in snippet view article find links to article
asparaginyl endopeptidase, citvac, proteinase B, hemoglobinase, PRSC1 gene product or LGMN (Homo sapiens), vicilin peptidohydrolase and bean endopeptidase
DUSP2 (719 words) [view diff] exact match in snippet view article find links to article
modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1 and ERK2, is predominantly expressed in hematopoietic
PTPRO (710 words) [view diff] exact match in snippet view article find links to article
intracellular catalytic domain with a characteristic signature motif. The gene product, which has a transmembrane domain, is an integral membrane protein. Several
GATA6 (1,407 words) [view diff] exact match in snippet view article find links to article
(GATA6), is protein that in humans is encoded by the GATA6 gene. The gene product preferentially binds (A/T/C)GAT(A/T)(A) of the consensus binding sequence
Fibrocystin (357 words) [view diff] exact match in snippet view article find links to article
the primary cilia of epithelial cells and co-localizes with the Pkd2 gene product polycystin-2 (PC2), suggesting that these two proteins may function in
Collagen, type V, alpha 3 (668 words) [view diff] exact match in snippet view article find links to article
heterotypic fibers composed of both type I and type V collagen. This gene product is closely related to type XI collagen and it is possible that the collagen
Survival of motor neuron (1,384 words) [view diff] exact match in snippet view article find links to article
DEAD box protein that interacts with SMN, the spinal muscular atrophy gene product, and is a component of gems". The Journal of Cell Biology. 147 (6): 1181–94
Related to receptor tyrosine kinase (893 words) [view diff] exact match in snippet view article find links to article
conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by
HLA-DR10 (284 words) [view diff] exact match in snippet view article find links to article
HLA-DR10 (DR10) is a HLA-DR serotype that recognizes the DRB1*1001 gene product. The serological reaction of DR10 is relatively good. DR10 serotype or
Carboxypeptidase D (644 words) [view diff] exact match in snippet view article find links to article
6, cereal serine carboxypeptidase II, Saccharomyces cerevisiae KEX1 gene product, carboxypeptidase Kex1, gene KEX1 serine carboxypeptidase, KEX1 carboxypeptidase
SLAMF1 (2,005 words) [view diff] exact match in snippet view article find links to article
D, et al. (October 1998). "The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM". Nature.
Snapalysin (181 words) [view diff] exact match in snippet view article find links to article
Snapalysin (EC 3.4.24.77, small neutral protease, SnpA gene product (Streptomyces lividans)) is an enzyme. This enzyme catalyses the following chemical
Ataxin 3 (1,245 words) [view diff] exact match in snippet view article find links to article
Kotliarova S, Kanazawa I, Nukina N (Jul 2000). "Ataxin-3, the MJD1 gene product, interacts with the two human homologs of yeast DNA repair protein RAD23
Ocular albinism type 1 (2,871 words) [view diff] exact match in snippet view article find links to article
receptor, or mutations of either the Tyr gene or P transporter. Human Oa1 gene product was initially identified as a 60kDa protein formed from a 46-48kDa precursor
Operon (2,544 words) [view diff] exact match in snippet view article find links to article
translated separately, i.e. several strands of mRNA that each encode a single gene product. The result of this is that the genes contained in the operon are either
Perilipin-3 (1,309 words) [view diff] exact match in snippet view article find links to article
(M6PRBP1) is a protein which in humans is encoded by the M6PRBP1 gene. Its gene product, as well as the gene itself, is commonly known as TIP47. Mannose 6-phosphate
Testican (239 words) [view diff] exact match in snippet view article find links to article
activated astroglial cells of the cerebrum. Several functions of this gene product have now been demonstrated in vitro including membrane-type matrix metalloproteinase
Collagen, type V, alpha 1 (1,067 words) [view diff] exact match in snippet view article find links to article
heterotypic fibers composed of both type I and type V collagen. This gene product is closely related to type XI collagen and it is possible that the collagen
Collagen, type V, alpha 2 (1,121 words) [view diff] exact match in snippet view article find links to article
heterotypic fibers composed of both type I and type V collagen. This gene product is closely related to type XI collagen and it is possible that the collagen
Collagen, type V, alpha 2 (1,121 words) [view diff] exact match in snippet view article find links to article
heterotypic fibers composed of both type I and type V collagen. This gene product is closely related to type XI collagen and it is possible that the collagen
EcoCyc (309 words) [view diff] exact match in snippet view article find links to article
Data objects in the EcoCyc database describe each E. coli gene and gene product. Database objects also describe molecular interactions, including metabolic
PDGFA (1,108 words) [view diff] exact match in snippet view article find links to article
mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer or as a heterodimer with the platelet-derived
Dipeptidase E (177 words) [view diff] exact match in snippet view article find links to article
Dipeptidase E (EC 3.4.13.21, aspartyl dipeptidase, peptidase E, PepE gene product (Salmonella typhimurium)) is an enzyme. This enzyme catalyses the following
HLA-DR9 (105 words) [view diff] exact match in snippet view article find links to article
HLA-DR09 (DR9) is a HLA-DR serotype that recognizes the DRB1*0901 gene product. The serological reaction of DR9 is relatively good. The serology of DRB1*0902
CD84 (1,302 words) [view diff] exact match in snippet view article find links to article
receptors Ly-9 and CD84 recruit the X-linked lymphoproliferative disease gene product SAP". Blood. 97 (12): 3867–74. doi:10.1182/blood.V97.12.3867. PMID 11389028
PDSS1 (594 words) [view diff] exact match in snippet view article find links to article
or ubiquinone, one of the key elements in the respiratory chain. The gene product catalyzes the formation of all trans-polyprenyl pyrophosphates from isopentyl
Collagen, type XIII, alpha 1 (893 words) [view diff] exact match in snippet view article find links to article
alpha chain of one of the nonfibrillar collagens. The function of this gene product is not known, however, it has been detected at low levels in all connective
DUSP10 (844 words) [view diff] exact match in snippet view article find links to article
modes of inducibility of their expression by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK, but not MAPK/ERK. Its subcellular
Wilms tumor protein (3,085 words) [view diff] exact match in snippet view article find links to article
in-frame with the first AUG, leading to additional isoforms. The WT1 gene product shows similarity to the zinc fingers of the mammalian growth regulated
C-terminal processing peptidase (255 words) [view diff] exact match in snippet view article find links to article
C-terminal processing peptidase (EC 3.4.21.102, CtpA gene product (Synechocystis sp.), photosystem II D1 protein processing peptidase, protease Re, tail-specific
KCNAB3 (346 words) [view diff] exact match in snippet view article find links to article
Bahring R, Isbrandt D, Pongs O (Feb 1999). "Coexpression of the KCNA3B gene product with Kv1.5 leads to a novel A-type potassium channel". J Biol Chem. 273
SH2D1A (1,846 words) [view diff] exact match in snippet view article find links to article
G, Terhorst C (Oct 1998). "The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM". Nature.
MT-CYB (1,863 words) [view diff] exact match in snippet view article find links to article
Cytochrome b is a protein that in humans is encoded by the MT-CYB gene. Its gene product is a subunit of the respiratory chain protein ubiquinol–cytochrome c
Amino acid synthesis (3,932 words) [view diff] exact match in snippet view article find links to article
well as repression through a repressor encoded by the gene argR. The gene product of argR, ArgR an aporepressor, and arginine as a corepressor affect the
HLA-C (1,014 words) [view diff] exact match in snippet view article find links to article
receptors. The C receptor is a heterodimer consisting of a HLA-C mature gene product and β2-microglobulin. The mature C chain is anchored in the membrane
RENBP (895 words) [view diff] exact match in snippet view article find links to article
2-epimerase is an enzyme that in humans is encoded by the RENBP gene. The gene product inhibits renin activity by forming a dimer with renin, a complex known
DnaQ (1,473 words) [view diff] exact match in snippet view article find links to article
complex. The gene encodes two functional domains: the N-terminus of the gene product binds the θ subunit and carries out the exonuclease function and the
Myc-tag (296 words) [view diff] exact match in snippet view article find links to article
A myc tag is a polypeptide protein tag derived from the c-myc gene product that can be added to a protein using recombinant DNA technology. It can be used
PDCD6 (1,245 words) [view diff] exact match in snippet view article find links to article
This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however
MMACHC (1,096 words) [view diff] exact match in snippet view article find links to article
protein involved in energy transduction for cobalamin uptake. The MMACHC gene product catalyzes the decyanation of cyanocobalamin as well as the dealkylation
CNTRL (642 words) [view diff] exact match in snippet view article find links to article
for the centrosome to function as a microtubule organizing center. The gene product is also associated with centrosome maturation. One version of stem cell
Complementation (genetics) (1,476 words) [view diff] exact match in snippet view article
assigned to different genes without the exact knowledge of what the gene product is doing on a molecular level. American geneticist Edward B. Lewis developed
GDF5 (1,063 words) [view diff] exact match in snippet view article find links to article
osteochondrodysplasia, Grebe type. These associations confirm that the gene product plays a role in skeletal development. GDF5 is expressed in the developing
CCNDBP1 (732 words) [view diff] exact match in snippet view article find links to article
the CCNDBP1 gene. This gene was identified by the interaction of its gene product with Grap2, a leukocyte-specific adaptor protein important for immune
ARID3B (320 words) [view diff] exact match in snippet view article find links to article
protein is homologous with two proteins that bind to the retinoblastoma gene product, and also with the mouse Bright and Drosophila dead ringer proteins.
SYT11 (512 words) [view diff] exact match in snippet view article find links to article
(October 2003). "The autosomal recessive juvenile Parkinson disease gene product, parkin, interacts with and ubiquitinates synaptotagmin XI". Human Molecular
ARID domain (609 words) [view diff] exact match in snippet view article find links to article
B-cell-specific gene expression), dead ringer (a Drosophila melanogaster gene product required for normal development), and MRF-2 (which represses expression
WNT3 (692 words) [view diff] exact match in snippet view article find links to article
identity to mouse Wnt3 protein, and 84% to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation
Yapsin 1 (220 words) [view diff] exact match in snippet view article find links to article
Yapsin 1 (EC 3.4.23.41, yeast aspartic protease 3, Yap3 gene product (Saccharomyces cerevisiae)) is an enzyme. This enzyme catalyses the following chemical
Treacle protein (1,465 words) [view diff] exact match in snippet view article find links to article
RB, Dixon J, Dixon MJ (2004). "The Treacher Collins syndrome (TCOF1) gene product is involved in ribosomal DNA gene transcription by interacting with upstream
Midkine (2,372 words) [view diff] exact match in snippet view article find links to article
bridges. It is a developmentally important retinoic acid-responsive gene product strongly induced during mid-gestation, hence the name midkine. Restricted
EIF3D (1,093 words) [view diff] exact match in snippet view article find links to article
"Inhibition of protein synthesis by the T cell receptor-inducible human TDAG51 gene product". Cellular Signalling. 13 (5): 345–352. doi:10.1016/S0898-6568(01)00141-3
ACADVL (987 words) [view diff] exact match in snippet view article find links to article
to long-chain and very-long-chain fatty acids. A deficiency in this gene product reduces myocardial fatty acid beta-oxidation and is associated with cardiomyopathy
60S ribosomal protein L14 (911 words) [view diff] exact match in snippet view article find links to article
"Inhibition of protein synthesis by the T cell receptor-inducible human TDAG51 gene product". Cell. Signal. 13 (5): 345–52. doi:10.1016/S0898-6568(01)00141-3. PMID 11369516
Na–K–Cl cotransporter (2,654 words) [view diff] exact match in snippet view article find links to article
from keeping (isoform 1) or skipping (isoform 2) exon 21 in the final gene product. NKCC1 is widely distributed throughout the human body; it has important
PDCD6IP (1,242 words) [view diff] exact match in snippet view article find links to article
manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins
Small nuclear ribonucleoprotein D1 (1,522 words) [view diff] exact match in snippet view article find links to article
DEAD box protein that interacts with SMN, the spinal muscular atrophy gene product, and is a component of gems". The Journal of Cell Biology. 147 (6): 1181–94
LY9 (849 words) [view diff] exact match in snippet view article find links to article
receptors Ly-9 and CD84 recruit the X-linked lymphoproliferative disease gene product SAP". Blood. 97 (12): 3867–3874. doi:10.1182/blood.V97.12.3867. PMID 11389028
Guanosine nucleotide dissociation inhibitor (550 words) [view diff] exact match in snippet view article find links to article
and oxidases. Conserved regions common to GDI and the choroideraemia gene product, which delivers Rab to catalytic subunits of Rab geranylgeranyltransferase
Hsp90 cis-regulatory element (126 words) [view diff] exact match in snippet view article find links to article
increased translational efficiency during the heat shock response. The hsp90 gene product is involved in the Drosophila heat shock response. Translation of the
Histidine (2,533 words) [view diff] exact match in snippet view article find links to article
and 8) and it occurs in ten steps. This is possible because a single gene product has the ability to catalyze more than one reaction. For example, as shown
HLA-DQ9 (513 words) [view diff] exact match in snippet view article find links to article
determined by the antibody recognition of β9 and this generally detects the gene product of DQB1*0303. The serotyping efficiency of DQ9 is poor. The recognition
CD99 (2,292 words) [view diff] exact match in snippet view article find links to article
1993). "Monoclonal antibodies directed against the E2 protein (MIC2 gene product) induce exposure of phosphatidylserine at the thymocyte cell surface"
Synthetic biological circuit (2,187 words) [view diff] exact match in snippet view article find links to article
self-regulating mechanisms to create a time-dependent oscillation of gene product expression. Toggle-switch Gardner et al. used mutual repression between
RAS p21 protein activator 1 (1,605 words) [view diff] exact match in snippet view article find links to article
cytoplasm and is part of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic
Retinoblastoma-like protein 1 (1,999 words) [view diff] exact match in snippet view article find links to article
function to the product of the retinoblastoma 1 (RB1) gene. The RB1 gene product is a tumor suppressor protein that appears to be involved in cell cycle
CMA1 (939 words) [view diff] exact match in snippet view article find links to article
Chymase is an enzyme that in humans is encoded by the CMA1 gene. This gene product is a chymotryptic serine proteinase that belongs to the peptidase family
Glycerol-1-phosphatase (483 words) [view diff] exact match in snippet view article find links to article
GPP1 gene product; M. tuberculosis (bacteria) via the rv1692 gene product; and C57BL/6N mice and Wistar rats (mammals) via the PGP gene product. Caparrós-Martín
Glycerol-1-phosphatase (483 words) [view diff] exact match in snippet view article find links to article
GPP1 gene product; M. tuberculosis (bacteria) via the rv1692 gene product; and C57BL/6N mice and Wistar rats (mammals) via the PGP gene product. Caparrós-Martín
Gem-associated protein 2 (1,126 words) [view diff] exact match in snippet view article find links to article
F, Dreyfuss G (September 1997). "The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal
KCNAB2 (879 words) [view diff] exact match in snippet view article find links to article
Kv-alpha subunits. This member alters functional properties of the KCNA4 gene product. Alternative splicing of this gene results in two transcript variants
TRIM27 (1,049 words) [view diff] exact match in snippet view article find links to article
N-terminus of this protein with the truncated C-terminus of the RET gene product has been shown to result in production of the ret transforming protein
TH (gene) (472 words) [view diff] no match in snippet view article
The TH gene codes for the enzyme tyrosine hydroxylase. Tyrosine hydroxylase is the rate limiting enzyme responsible for the transformation of L-Tyrosine
Immunoscreening (241 words) [view diff] exact match in snippet view article find links to article
antibody-peptide interactions. Clones are screened for the presence of the gene product: the resulting protein. This strategy requires first that a gene library
CREBL1 (854 words) [view diff] exact match in snippet view article find links to article
"Identification of the G13 (cAMP-response-element-binding protein-related protein) gene product related to activating transcription factor 6 as a transcriptional activator
Glucose-6-phosphate isomerase (3,057 words) [view diff] exact match in snippet view article find links to article
to perform mechanistically distinct functions. In the cytoplasm, the gene product functions as a glycolytic enzyme (glucose-6-phosphate isomerase) that
PAFAH1B1 (1,513 words) [view diff] exact match in snippet view article find links to article
Albrecht U, Reiner O, Eichele G, Yu-Lee LY (May 1998). "The lissencephaly gene product Lis1, a protein involved in neuronal migration, interacts with a nuclear
Lewis antigen system (1,784 words) [view diff] exact match in snippet view article find links to article
the A gene product acts on the H antigen and adds an N-acetylgalactosamine, the A antigen results and the person is type A. When the B gene product acts
ECH1 (557 words) [view diff] exact match in snippet view article find links to article
This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-CoA hydratases of several species
MYO7A (1,718 words) [view diff] case mismatch in snippet view article find links to article
at the PDBe-KB. Wolfrum U (2003). "The Cellular Function of the Usher Gene Product Myosin VIIa is Specified by Its Ligands". Retinal Degenerations. Advances
RNAI (286 words) [view diff] exact match in snippet view article find links to article
This rate of degradation is aided by the pcnB (plasmid copy number B) gene product, which polyadenylates the 3' end of RNAI targeting it for degradation
Fragile X-associated tremor/ataxia syndrome (1,303 words) [view diff] exact match in snippet view article find links to article
transcriptionally silenced via DNA methylation. In both diseases the FMR1 gene product, Fragile X mental retardation protein (FMRP) is diminished, but in FXTAS
DDX20 (1,639 words) [view diff] exact match in snippet view article find links to article
survival of motor neuron (SMN) complex. SMN is the spinal muscular atrophy gene product, and may play a catalytic role in the function of the SMN complex on
Tripeptidyl peptidase I (1,650 words) [view diff] exact match in snippet view article find links to article
characterization of bovine brain lysosomal pepstatin-insensitive proteinase, the gene product deficient in the human late-infantile neuronal ceroid lipofuscinosis"
SPG21 (498 words) [view diff] exact match in snippet view article find links to article
hydrolase fold domain of this protein. It is thus proposed that this gene product modulates the stimulatory activity of CD4. SPG21 has been shown to interact
PTTG1 (1,388 words) [view diff] exact match in snippet view article find links to article
The gene product has transforming activity in vitro and tumorigenic activity in vivo, and the gene is highly expressed in various tumors. The gene product
Batten disease (3,610 words) [view diff] exact match in snippet view article find links to article
which produces a truncated mutant gene product of only 181 amino acids in length when compared to the wild-type gene product of 438 amino acids in length.
UQCRH (491 words) [view diff] exact match in snippet view article find links to article
mitochondrial is a protein that in humans is encoded by the UQCRH gene. Its gene product is a subunit of the respiratory chain protein Ubiquinol Cytochrome c
ARID4A (1,052 words) [view diff] exact match in snippet view article find links to article
"Cloning of cDNAs for cellular proteins that bind to the retinoblastoma gene product". Nature. 352 (6332): 251–4. Bibcode:1991Natur.352..251D. doi:10.1038/352251a0
Pleiotropy (5,016 words) [view diff] exact match in snippet view article find links to article
pleiotropy, and selectional pleiotropy. Gene pleiotropy occurs when a gene product interacts with multiple other proteins or catalyzes multiple reactions
Replication factor C (866 words) [view diff] exact match in snippet view article find links to article
Replication factor C is an emergency backup factor for DNA polymerases. RFC2 gene product required for a cell cycle checkpoint. RFC is a heteropentamer in budding
HLA-DP (905 words) [view diff] exact match in snippet view article find links to article
of Super B8. Each combination of DPA1 allele gene product with each combination of DPB1 'gene' product can potentially recombine to produce one isoform
TOP3A (1,648 words) [view diff] exact match in snippet view article find links to article
JF, Turley H, Gatter KC, Hickson ID (Mar 2000). "The Bloom's syndrome gene product interacts with topoisomerase III". The Journal of Biological Chemistry
List of proteins (794 words) [view diff] exact match in snippet view article find links to article
The human genome, categorized by function of each gene product, given both as number of genes and as percentage of all genes.
Cyanocobalamin (2,663 words) [view diff] exact match in snippet view article find links to article
adenosylcobalamin are commercially available as supplement pills. The MMACHC gene product catalyzes the decyanation of cyanocobalamin as well as the dealkylation
HgcC family RNA (278 words) [view diff] exact match in snippet view article find links to article
hgcC". A further RNA element, SscA RNA, was also identified. The HgcC gene product was experimentally validated by Northern blot and RACE-PCR analysis.
PMEL (gene) (1,534 words) [view diff] exact match in snippet view article
(gp100), is a protein that in humans is encoded by the PMEL gene. Its gene product may be referred to as PMEL, silver, ME20, gp100 or Pmel17. PMEL is a
UQCRC1 (814 words) [view diff] exact match in snippet view article find links to article
mitochondrial is a protein that in humans is encoded by the UQCRC1 gene. Its gene product is a subunit of the respiratory chain protein Ubiquinol Cytochrome c
HSN2 (363 words) [view diff] exact match in snippet view article find links to article
plentiful in sensory neurons than motor neurons. It is proposed that this gene product may play a role in the development and/or maintenance of peripheral sensory
POU3F4 (1,138 words) [view diff] exact match in snippet view article find links to article
EB (1998). "3rd Changes in the subcellular localization of the Brn4 gene product precede mesenchymal remodeling of the otic capsule". Hear. Res. 120 (1–2):
AGTRAP (708 words) [view diff] exact match in snippet view article find links to article
localized to the plasma membrane and perinuclear vesicular structures. The gene product interacts with the angiotensin II type I receptor and negatively regulates
PCDH7 (471 words) [view diff] exact match in snippet view article find links to article
protein with an extracellular domain containing 7 cadherin repeats. The gene product is an integral membrane protein that is thought to function in cell–cell
PPP1R12B (774 words) [view diff] exact match in snippet view article find links to article
phosphatase target subunit 1. sm-M20 shows higher binding affinity to this gene product than to myosin light chain phosphatase target subunit 2-MBS even though
METTL1 (480 words) [view diff] exact match in snippet view article find links to article
This gene is similar in sequence to the S. cerevisiae YDL201w gene. The gene product contains a conserved S-adenosylmethionine-binding motif and is inactivated
Tuberous sclerosis protein (1,075 words) [view diff] exact match in snippet view article find links to article
Wienecke R, DeClue JE (December 2000). "The tuberous sclerosis-1 (TSC1) gene product hamartin suppresses cell growth and augments the expression of the TSC2
UNC5C (576 words) [view diff] exact match in snippet view article find links to article
UNC5C is a protein that in humans is encoded by the UNC5C gene. This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted
MYBL2 (1,486 words) [view diff] exact match in snippet view article find links to article
S (August 1994). "Multiple nuclear localization signals of the B-myb gene product". FEBS Letters. 350 (1): 55–60. Bibcode:1994FEBSL.350...55T. doi:10
Viral structural protein (329 words) [view diff] no match in snippet view article find links to article
wild-type and amber mutants and their possible implications as to type of gene-product function: catalytic vs. stoichiometric. Virology. 1968;35(4):550-563
YY1AP1 (703 words) [view diff] exact match in snippet view article find links to article
a protein that in humans is encoded by the YY1AP1 gene. The encoded gene product presumably interacts with YY1 protein; however, its exact function is
KCNAB1 (985 words) [view diff] exact match in snippet view article find links to article
Shaker K+ channel beta 1 gene and functional expression of the beta 2 gene product". FEBS Lett. 370 (1–2): 32–6. Bibcode:1995FEBSL.370...32M. doi:10
Retron (796 words) [view diff] exact match in snippet view article find links to article
tyr-ala-asp-asp (YADD) sequence associated with the catalytic core. The ret gene product is responsible for processing the msd/msr portion of the RNA transcript
IL1RL1 (2,424 words) [view diff] exact match in snippet view article find links to article
(October 1999). "Presence and expression of a novel variant form of ST2 gene product in human leukemic cell line UT-7/GM". Biochemical and Biophysical Research
Small nuclear ribonucleoprotein polypeptide E (1,093 words) [view diff] exact match in snippet view article find links to article
DEAD box protein that interacts with SMN, the spinal muscular atrophy gene product, and is a component of gems". The Journal of Cell Biology. 147 (6): 1181–94
SEC24D (503 words) [view diff] exact match in snippet view article find links to article
complex responsible for vesicle budding from the ER. The role of this gene product is implicated in the shaping of the vesicle, and also in cargo selection
VAV3 (799 words) [view diff] exact match in snippet view article find links to article
actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent,
STEAP1 (484 words) [view diff] exact match in snippet view article find links to article
tissue, and is found to be upregulated in multiple cancer cell lines. The gene product is predicted to be a six-transmembrane protein, and was shown to be a
SNRPB (1,171 words) [view diff] exact match in snippet view article find links to article
DEAD box protein that interacts with SMN, the spinal muscular atrophy gene product, and is a component of gems". J. Cell Biol. 147 (6): 1181–94. doi:10
STEAP1 (484 words) [view diff] exact match in snippet view article find links to article
tissue, and is found to be upregulated in multiple cancer cell lines. The gene product is predicted to be a six-transmembrane protein, and was shown to be a
SPEN (855 words) [view diff] exact match in snippet view article find links to article
inducible transcriptional repressor. Repression of transcription by this gene product can occur through interactions with other repressors, by the recruitment
DGCR6 (555 words) [view diff] exact match in snippet view article find links to article
are associated with microdeletions in chromosomal region 22q11.2. This gene product shares homology with the Drosophila melanogaster gonadal protein, which
RMRP (872 words) [view diff] exact match in snippet view article find links to article
The enzyme is a ribonucleoprotein whose RNA component is a nuclear gene product. The RNA component is the first RNA encoded by a single-copy gene in
Galactoside acetyltransferase (253 words) [view diff] exact match in snippet view article find links to article
studies of galactoside acetyltransferase, the Escherichia coli LacA gene product". The Journal of Biological Chemistry. 270 (44): 26326–31. doi:10.1074/jbc
PDCD7 (466 words) [view diff] exact match in snippet view article find links to article
to ceramide-mediated signalling. These observations suggest that this gene product is involved in specific apoptotic processes in T-cells. GRCh38: Ensembl
Stringent response (766 words) [view diff] exact match in snippet view article find links to article
pppGpp is converted to ppGpp by the gpp gene product, releasing Pi. ppGpp is converted to GDP by the spoT gene product, releasing pyrophosphate (PPi). GDP
SNRPD3 (1,183 words) [view diff] exact match in snippet view article find links to article
DEAD box protein that interacts with SMN, the spinal muscular atrophy gene product, and is a component of gems". J. Cell Biol. 147 (6): 1181–94. doi:10
WASF3 (825 words) [view diff] exact match in snippet view article find links to article
encodes a member of the Wiskott–Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases
VNN1 (612 words) [view diff] exact match in snippet view article find links to article
Pantetheinase is an enzyme that in humans is encoded by the VNN1 gene. This gene product is a member of the Vanin family of proteins which share extensive sequence
Heredity (3,747 words) [view diff] exact match in snippet view article find links to article
dominant-negative process, wherein a mutated gene product adversely affects the non-mutated gene product within the same cell. Hard inheritance Lamarckism
KDELR2 (589 words) [view diff] exact match in snippet view article find links to article
identified, and it encodes a protein which is 83% identical to the KDELR1 gene product. Pathogenic variants in KDELR2 have been linked to Osteogenesis imperfecta
DSE (gene) (622 words) [view diff] exact match in snippet view article
in cancer patients and may be useful for specific immunotherapy. This gene product is localized to the endoplasmic reticulum. Two transcript variants encoding
SELENBP1 (723 words) [view diff] exact match in snippet view article find links to article
1 is a protein that in humans is encoded by the SELENBP1 gene. This gene product belongs to the selenium-binding protein family. Selenium is an essential
WASL (gene) (1,332 words) [view diff] exact match in snippet view article
filaments, and the cytoskeletal organizing complex, Arp2/3. The WASL gene product is a homolog of WAS protein, however, unlike the latter, it is ubiquitously
ANAPC4 (795 words) [view diff] exact match in snippet view article find links to article
conserved in organisms from yeast to humans. The exact function of this gene product is not known. ANAPC4 has been shown to interact with ANAPC1, ANAPC5,
NPM3 (437 words) [view diff] exact match in snippet view article find links to article
murine Npm3 gene. Based on the structural similarity of the human NPM3 gene product to nucleoplasmin and nucleophosmin, NPM3 may represent a new member of
Heterotopia (medicine) (505 words) [view diff] exact match in snippet view article
a gene product from what is typically found in one area to another area. It can also be further expanded to a subtle form of exaptation where a gene product
Ataxin 1 (1,998 words) [view diff] exact match in snippet view article find links to article
coilin, a coiled body-specific protein, interacts with ataxin-1, the SCA1 gene product". Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1638
Bx1 benzoxazin1 (1,496 words) [view diff] no match in snippet view article find links to article
Function Maize gene for first step in biosynthesis of benzoxazin, which aids in resistance to insect pests, pathogenic fungi and bacteria. First report
YAF2 (483 words) [view diff] exact match in snippet view article find links to article
protein involved in negative regulation of muscle-restricted genes. This gene product itself contains a single N-terminal C2-X10-C2 zinc finger, and in contrast
Small nuclear ribonucleoprotein D2 (1,233 words) [view diff] exact match in snippet view article find links to article
DEAD box protein that interacts with SMN, the spinal muscular atrophy gene product, and is a component of gems". J. Cell Biol. 147 (6). UNITED STATES: 1181–94
SEC14L1 (444 words) [view diff] exact match in snippet view article find links to article
to Japanese flying squid RALBP which suggests a possible role of the gene product in an intracellular transport system. GRCh38: Ensembl release 89: ENSG00000129657
Myotonin-protein kinase (2,426 words) [view diff] exact match in snippet view article find links to article
(DMPK) is an enzyme that in humans is encoded by the DMPK gene. The DMPK gene product is a Ser/Thr protein kinase homologous to the MRCK p21-activated kinases
HAX1 (1,053 words) [view diff] exact match in snippet view article find links to article
F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate
Exosome component 6 (516 words) [view diff] exact match in snippet view article find links to article
MTR3 is an enzyme that in humans is encoded by the EXOSC6 gene. This gene product constitutes one of the subunits of the multisubunit particle called the
MMP8 (1,257 words) [view diff] exact match in snippet view article find links to article
Mainardi CL (July 1990). "Human neutrophil collagenase. A distinct gene product with homology to other matrix metalloproteinases". J. Biol. Chem. 265
BCCIP (982 words) [view diff] exact match in snippet view article find links to article
protein is a protein that is encoded by the BCCIP gene in humans. This gene product was isolated based on its interaction with BRCA2 and p21 proteins. It
UBE2A (1,140 words) [view diff] exact match in snippet view article find links to article
Sumanasekera W, Zhang Y, Wu X, Wang Z (July 2000). "The human RAD18 gene product interacts with HHR6A and HHR6B". Nucleic Acids Research. 28 (14): 2847–2854
BRD2 (1,177 words) [view diff] exact match in snippet view article find links to article
BRD4, and BRDT in mammals Early descriptions demonstrated that BRD2 gene product is a mitogen-activated kinase which localizes to the nucleus. The gene
CIDEA (744 words) [view diff] exact match in snippet view article find links to article
to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Two alternative transcripts
AU-rich element (1,425 words) [view diff] exact match in snippet view article find links to article
gene or GM-CSF gene in mice leads to over expression of each respective gene product, causing dramatic disease phenotypes. AREs have been divided into three
NMNAT2 (828 words) [view diff] exact match in snippet view article find links to article
(NMNAT2) is an enzyme that in humans is encoded by the NMNAT2 gene. This gene product belongs to the nicotinamide-nucleotide adenylyltransferase (NMNAT) enzyme
Northern blot (2,120 words) [view diff] exact match in snippet view article find links to article
controls for comparison in a northern blot, samples not displaying the gene product of interest can be used after determination by microarrays or RT-PCR
PDLIM7 (759 words) [view diff] exact match in snippet view article find links to article
protein kinases, whereas the PDZ domain binds to actin filaments. The gene product is involved in the assembly of an actin filament-associated complex essential
VNN2 (766 words) [view diff] exact match in snippet view article find links to article
molecule 2 is a protein that in humans is encoded by the VNN2 gene. This gene product is a member of the Vanin family of proteins which share extensive sequence
Halloween genes (1,017 words) [view diff] exact match in snippet view article find links to article
(Cyp307a1) is expressed in the prothoracic gland, and in conjunction with the gene product of spookier (Cyp307a2), converts 7-dehydrocholesterol to Δ4-diketol.
PURB (713 words) [view diff] exact match in snippet view article find links to article
Pur-beta is a protein that in humans is encoded by the PURB gene. This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds
Craig M. Crews (2,879 words) [view diff] exact match in snippet view article find links to article
that phosphorylates and activates the Erk-1 gene product: relationship to the fission yeast byr1 gene product". Proceedings of the National Academy of Sciences
SYNGR1 (590 words) [view diff] exact match in snippet view article find links to article
synaptic plasticity without being required for synaptic transmission. The gene product belongs to the synaptogyrin gene family. Three alternatively spliced
UBE2B (969 words) [view diff] exact match in snippet view article find links to article
Sumanasekera W, Zhang Y, Wu X, Wang Z (July 2000). "The human RAD18 gene product interacts with HHR6A and HHR6B". Nucleic Acids Res. 28 (14). ENGLAND:
Grancalcin (645 words) [view diff] exact match in snippet view article find links to article
Grancalcin is a protein that in humans is encoded by the GCA gene. This gene product, grancalcin, is a calcium-binding protein abundant in neutrophils and
Extracellular signal-regulated kinases (1,128 words) [view diff] exact match in snippet view article find links to article
that phosphorylates and activates the Erk-1 gene product: relationship to the fission yeast byr1 gene product". Proceedings of the National Academy of Sciences
FEZ1 (1,052 words) [view diff] exact match in snippet view article find links to article
that it also functions in axonal outgrowth. The N-terminal half of the gene product is highly acidic. Alternatively spliced transcript variants encoding
SEC24B (423 words) [view diff] exact match in snippet view article find links to article
complex responsible for vesicle budding from the ER. The role of this gene product is implicated in the shaping of the vesicle, and also in cargo selection
VPREB3 (595 words) [view diff] exact match in snippet view article find links to article
is a protein that in humans is encoded by the VPREB3 gene. The VPREB3 gene product is the human homologue of the mouse VpreB3 (8HS20) protein, and is specifically
Dictyoglomus thermophilum (350 words) [view diff] exact match in snippet view article find links to article
the xynB gene from Dictyoglomus thermophilum Rt46B.1 and action of the gene product on kraft pulp". Appl. Environ. Microbiol. 64 (5): 1759–65. Bibcode:1998ApEnM
Grancalcin (645 words) [view diff] exact match in snippet view article find links to article
Grancalcin is a protein that in humans is encoded by the GCA gene. This gene product, grancalcin, is a calcium-binding protein abundant in neutrophils and
RASA3 (963 words) [view diff] exact match in snippet view article find links to article
gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic
SFXN1 (685 words) [view diff] exact match in snippet view article find links to article
humans is encoded by the SFXN1 gene. According to Nora Kory et al., SFXN1 gene product has mitochondrial serine transporter activity. GRCh38: Ensembl release
SYNGR1 (590 words) [view diff] exact match in snippet view article find links to article
synaptic plasticity without being required for synaptic transmission. The gene product belongs to the synaptogyrin gene family. Three alternatively spliced
PES1 (889 words) [view diff] exact match in snippet view article find links to article
containing a BRCT domain that is essential for the activity of this gene product. The gene plays a crucial role in cell proliferation and may be necessary
SCAMP2 (625 words) [view diff] exact match in snippet view article find links to article
protein 2 is a protein that in humans is encoded by the SCAMP2 gene. This gene product belongs to the SCAMP family of proteins which are secretory carrier membrane
POLRMT (793 words) [view diff] exact match in snippet view article find links to article
This gene encodes a mitochondrial DNA-directed RNA polymerase. The gene product is responsible for mitochondrial gene expression as well as for providing
RASGRF1 (187 words) [view diff] exact match in snippet view article find links to article
exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the
Serrate RNA effector molecule homolog (569 words) [view diff] exact match in snippet view article find links to article
(ARS2) is a protein that in humans is encoded by the SRRT gene. The SRRT gene product plays a role in RNA-mediated gene silencing (RNAi) by miRNAs. Independently
Inosine monophosphate synthase (788 words) [view diff] exact match in snippet view article find links to article
Medicine. Rayl EA, Moroson BA, Beardsley GP (Mar 1996). "The human purH gene product, 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP
Tektin-1 (406 words) [view diff] exact match in snippet view article find links to article
Tektin-1 is a protein that in humans is encoded by the TEKT1 gene. This gene product belongs to the tektin family of proteins. Tektins comprise a family of
SEPTIN4 (570 words) [view diff] exact match in snippet view article find links to article
long. There are currently no experimental structures for the SEPTIN4 gene product with a sequence identity >90%. Although SEPTIN4 is predicted to be an
Lac operon (5,255 words) [view diff] exact match in snippet view article find links to article
and their subsequent proteins translated: lacZ, lacY, and lacA. The gene product of lacZ is β-galactosidase which cleaves lactose, a disaccharide, into
CIDEA (744 words) [view diff] exact match in snippet view article find links to article
to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Two alternative transcripts
Atrophin 1 (1,923 words) [view diff] exact match in snippet view article find links to article
(September 2000). "Atrophin-1, the dentato-rubral and pallido-luysian atrophy gene product, interacts with ETO/MTG8 in the nuclear matrix and represses transcription"
ESM1 (715 words) [view diff] exact match in snippet view article find links to article
contains multiple polyadenylation and mRNA instability signals. The ESM-1 gene product is also called endocan since 2001, when it was characterized as a dermatan
WFDC1 (569 words) [view diff] exact match in snippet view article find links to article
Owing to its location and a possible growth inhibitory property of its gene product, this gene is suggested to be a tumor suppressor gene. GRCh38: Ensembl
ZFP91 (587 words) [view diff] exact match in snippet view article find links to article
by this gene is a member of the zinc finger family of proteins. The gene product contains C2H2 type domains, which are the classical zinc finger domains
HIRIP3 (477 words) [view diff] exact match in snippet view article find links to article
HIRA-interacting proteins, or HIRIPs, have been identified. In vitro, the HIRIP3 gene product binds HIRA, as well as H2B and H3 core histones, indicating that a complex
IFT140 (687 words) [view diff] exact match in snippet view article find links to article
homolog, is a protein that in humans is encoded by the IFT140 gene. The gene product forms a core component of IFT-A complex which is indipensible for retrograde
SART3 (1,146 words) [view diff] exact match in snippet view article find links to article
in cancer patients and may be useful for specific immunotherapy. This gene product is found to be an important cellular factor for HIV-1 gene expression
YES and YAS assay (523 words) [view diff] exact match in snippet view article find links to article
initiates a cascade of events leading to the expression of the reporter gene product (e.g. β-galctosidase) which converts a substrate (e.g. CPRG) which leads
Ubiquitin carboxy-terminal hydrolase L1 (2,637 words) [view diff] exact match in snippet view article find links to article
Rasmussen HH, Vandekerckhove J, Celis JE (Mar 1991). "Neuronal protein gene product 9.5 (IEF SSP 6104) is expressed in cultured human MRC-5 fibroblasts of
TMEM123 (704 words) [view diff] exact match in snippet view article find links to article
by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell
GTF2A1L (815 words) [view diff] exact match in snippet view article find links to article
protein consisting of sequence sharing identity with each individual gene product. GRCm38: Ensembl release 89: ENSMUSG00000024154 – Ensembl, May 2017 "Human
Reporter gene (1,981 words) [view diff] exact match in snippet view article find links to article
polypeptide linker region is usually included so that the reporter and the gene product will only minimally interfere with one another. Reporter genes can also
Ed Harlow (828 words) [view diff] exact match in snippet view article find links to article
papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product." Science 243.4893 (1989): 934–937. Whyte, Peter, et al. "Association
Brain mitochondrial carrier protein 1 (1,733 words) [view diff] exact match in snippet view article find links to article
in many tissues with the greatest abundance in brain and testis. The gene product has an N-terminal hydrophobic domain that is not present in other UCPs
Express (538 words) [view diff] exact match in snippet view article find links to article
which information from a gene is used in the synthesis of a functional gene product All pages with titles beginning with Express All pages with titles containing
WASF2 (1,041 words) [view diff] exact match in snippet view article find links to article
encodes a member of the Wiskott–Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases
Alkb homolog 1, histone h2a dioxygenase (584 words) [view diff] exact match in snippet view article find links to article
by the ALKBH1 gene. This gene encodes a homolog to the E. coli alkB gene product. The E. coli alkB protein is part of the adaptive response mechanism
MFD (219 words) [view diff] exact match in snippet view article find links to article
for presenting various information Mutation Frequency Decline, a gene/gene product used in transcription-coupled repair Multifunction device, an office
Early protein (441 words) [view diff] no match in snippet view article find links to article
wild-type and amber mutants and their possible implications as to type of gene-product function: catalytic vs. stoichiometric". Virology. 35 (4): 550–63. doi:10
L3MBTL (710 words) [view diff] exact match in snippet view article find links to article
neuroblasts and ganglion mother cells in the optic centers of the brain. This gene product is localized to condensed chromosomes in mitotic cells. Overexpression
Period (gene) (2,385 words) [view diff] exact match in snippet view article
Hall JC, Rosbash M (February 1990). "Feedback of the Drosophila period gene product on circadian cycling of its messenger RNA levels". Nature. 343 (6258):
Cell division cycle 7-related protein kinase (1,746 words) [view diff] exact match in snippet view article find links to article
a role in regulating cell cycle progression. Overexpression of this gene product may be associated with neoplastic transformation for some tumors. Additional
Olfactomedin 1 (698 words) [view diff] exact match in snippet view article find links to article
"neuronal olfactomedin-related endoplasmic reticulum-localized 1". This gene product shares extensive sequence similarity with the rat neuronal olfactomedin-related
DnaC (231 words) [view diff] exact match in snippet view article find links to article
Kobori JA, Kornberg A (November 1982). "The Escherichia coli dnaC gene product. III. Properties of the dnaB-dnaC protein complex". The Journal of Biological
TST (gene) (866 words) [view diff] exact match in snippet view article
iron-sulfur proteins, and the modification of sulfur-containing enzymes. The gene product contains two highly conservative domains (rhodanese homology domains)
Nasonia vitripennis (1,282 words) [view diff] exact match in snippet view article find links to article
Hymenoptera, determination of sex in development, and many protein and gene product comparisons to other insects have been studied using N. vitripennis (most
TAS2R8 (466 words) [view diff] exact match in snippet view article find links to article
member 8 is a protein that in humans is encoded by the TAS2R8 gene. This gene product belongs to the family of candidate taste receptors that are members of
Aryl hydrocarbon receptor nuclear translocator (1,768 words) [view diff] exact match in snippet view article find links to article
Moffett P, Reece M, Pelletier J (September 1997). "The murine Sim-2 gene product inhibits transcription by active repression and functional interference"
FARSA (gene) (539 words) [view diff] exact match in snippet view article
Saccharomyces cerevisiae phenylalanyl-tRNA synthetases (PheRS). This gene product has been shown to be expressed in a tumor-selective and cell cycle stage-
SKBR3 (363 words) [view diff] exact match in snippet view article find links to article
43-year-old caucasian female. The cell line over-expresses the HER2 gene product, which has been implicated in several breast cancer proliferation pathways
YWHAG (1,363 words) [view diff] exact match in snippet view article find links to article
gamma is a protein that in humans is encoded by the YWHAG gene. This gene product belongs to the 14-3-3 protein family which mediate signal transduction
THRSP (834 words) [view diff] exact match in snippet view article find links to article
by the THRSP gene. The protein encoded by this gene is similar to the gene product of S14, a rat gene whose expression is limited to liver and adipose tissue
Runt domain (334 words) [view diff] exact match in snippet view article find links to article
interaction. In addition to the highly conserved Runt domain, the AML-1 gene product carries a putative ATP-binding site (GRSGRGKS), and has a C-terminal
ALG2 (917 words) [view diff] exact match in snippet view article find links to article
calcium binding protein ALG-2 binds and stabilizes Scotin, a p53-inducible gene product localized at the endoplasmic reticulum membrane". Archives of Biochemistry
CA8 (660 words) [view diff] exact match in snippet view article find links to article
genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry
Retinoblastoma protein (9,501 words) [view diff] exact match in snippet view article find links to article
Wang NP, Qian YW, Lee EY, Lee WH (October 1991). "The retinoblastoma gene product regulates progression through the G1 phase of the cell cycle". Cell.
HAS1 (1,067 words) [view diff] exact match in snippet view article find links to article
and its amino acid sequence shows significant homology to the hasA gene product of Streptococcus pyogenes, a glycosaminoglycan synthetase (DG42) from
GNA12 (861 words) [view diff] exact match in snippet view article find links to article
cDNA cloning of a transforming gene encoding the wild-type G alpha 12 gene product". Molecular and Cellular Biology. 13 (2): 762–8. doi:10.1128/mcb.13.2
PDCD5 (988 words) [view diff] exact match in snippet view article find links to article
of the apoptosis-inducing stimuli. Prior to apoptosis induction, this gene product is distributed in both the nucleus and cytoplasm. Once apoptosis is induced
PLK1 (1,929 words) [view diff] exact match in snippet view article find links to article
CHO1/MKLP1. The homologous motor protein in Drosophila is the pavarotti gene product (PAR). Studies have shown that the loss of PLK1 expression can induce
PPAN (956 words) [view diff] exact match in snippet view article find links to article
evolutionarily conserved protein similar to yeast SSF1 as well as to the gene product of the Drosophila gene peter pan (PPAN). SSF1 is known to be involved
NUDT2 (832 words) [view diff] exact match in snippet view article find links to article
pyrophosphatases, a subset of the larger NUDIX hydrolase family. The gene product possesses a modification of the MutT sequence motif found in certain
WAC (gene) (692 words) [view diff] exact match in snippet view article
peptide motifs that are proline-rich or contain at least one proline. This gene product shares 94% sequence identity with the WAC protein in mouse, however,
Coilin (1,351 words) [view diff] exact match in snippet view article find links to article
coilin, a coiled body-specific protein, interacts with ataxin-1, the SCA1 gene product". Biochim. Biophys. Acta. 1638 (1): 35–42. doi:10.1016/s0925-4439(03)00038-3
SEMA3F (1,081 words) [view diff] exact match in snippet view article find links to article
al., 1995), a putative homolog of an axonal guidance associated UNC33 gene product (MIM 601168). SEMA3F is a secreted member of the semaphorin III family
Hok/sok system (1,446 words) [view diff] exact match in snippet view article find links to article
postsegregational killing by the hok gene product of the parB system of plasmid R1 and its homology with the relF gene product of the E. coli relB operon". EMBO
TAS2R7 (488 words) [view diff] exact match in snippet view article find links to article
member 7 is a protein that in humans is encoded by the TAS2R7 gene. This gene product belongs to the family of candidate taste receptors that are members of
TAS2R9 (520 words) [view diff] exact match in snippet view article find links to article
member 9 is a protein that in humans is encoded by the TAS2R9 gene. This gene product belongs to the family of candidate taste receptors that are members of
ABCA1 (2,084 words) [view diff] exact match in snippet view article find links to article
Schwartz K, Porter JG, et al. (October 1999). "The Tangier disease gene product ABC1 controls the cellular apolipoprotein-mediated lipid removal pathway"
Plakoglobin (4,698 words) [view diff] exact match in snippet view article find links to article
(Aug 1994). "Association of plakoglobin with APC, a tumor suppressor gene product, and its regulation by tyrosine phosphorylation". Biochemical and Biophysical
TAS2R13 (488 words) [view diff] exact match in snippet view article find links to article
13 is a protein that in humans is encoded by the TAS2R13 gene. This gene product belongs to the family of candidate taste receptors that are members of
NFKBIZ (1,238 words) [view diff] exact match in snippet view article find links to article
through ankyrin-repeat domains. Studies in mouse indicate that this gene product is one of the nuclear I kappa B proteins and an activator of IL-6 production
TRAF3IP2 (1,139 words) [view diff] exact match in snippet view article find links to article
immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated
Autosome (1,089 words) [view diff] exact match in snippet view article find links to article
aneuploidy are the result of improper gene dosage, not nonfunctional gene product. Aneuploidy (abnormal number of chromosomes) Autosomal dominant Autosomal
Monoecy (1,126 words) [view diff] exact match in snippet view article find links to article
undergo meiosis to produce pollen grains. Meiosis in maize requires gene product RAD51, a protein employed in recombinational repair of DNA double-strand
Small nuclear ribonucleoprotein polypeptide F (984 words) [view diff] exact match in snippet view article find links to article
DEAD box protein that interacts with SMN, the spinal muscular atrophy gene product, and is a component of gems". The Journal of Cell Biology. 147 (6): 1181–94
Dual specificity phosphatase 8 (301 words) [view diff] exact match in snippet view article find links to article
modes of inducibility of their expression by extracellular stimuli. This gene product inactivates SAPK/JNK and p38, is expressed predominantly in the adult
PABPC4 (932 words) [view diff] exact match in snippet view article find links to article
"Inhibition of protein synthesis by the T cell receptor-inducible human TDAG51 gene product". Cell. Signal. 13 (5): 345–52. doi:10.1016/S0898-6568(01)00141-3. PMID 11369516
Genetic disorder (3,613 words) [view diff] exact match in snippet view article find links to article
dominant-negative process, wherein a mutated gene product adversely affects the non-mutated gene product within the same cell. X-linked dominant disorders
Env (gene) (2,253 words) [view diff] exact match in snippet view article
protein. See Replication cycle of HIV. Env expression is regulated by the gene product of rev. Experimental deletion of rev resulted in the inability to detect
Fatty-acid peroxygenase (448 words) [view diff] exact match in snippet view article find links to article
Sumimoto T, Ichihara K (August 1999). "Characterization of the ybdT gene product of Bacillus subtilis: novel fatty acid beta-hydroxylating cytochrome
Ischemic cell death (866 words) [view diff] exact match in snippet view article find links to article
intracellular ATP levels, initiating the oncotic pathway. The anti-apoptotic gene product Bcl-2 is not an active inhibitor of UCP-2 initiated cell death, further
Sialidase-3 (1,122 words) [view diff] exact match in snippet view article find links to article
Sialidase-3 is an enzyme that in humans is encoded by the NEU3 gene. This gene product belongs to a family of glycohydrolytic enzymes which remove sialic acid
Precorrin-8X methylmutase (357 words) [view diff] exact match in snippet view article find links to article
in the biosynthesis of hydrogenobyrinic acid is catalyzed by the cobH gene product with precorrin-8x as the substrate". J. Bacteriol. 174 (3): 1043–9. doi:10
Chaperonin (2,320 words) [view diff] exact match in snippet view article find links to article
chaperonins, the general structure and mechanism are conserved. The gene product 31 (gp31) of bacteriophage T4 is a protein required for bacteriophage
ALOX15 (5,708 words) [view diff] exact match in snippet view article find links to article
products. ▼ Gene Function Kelavkar and Badr (1999) stated that the ALOX15 gene product is implicated in antiinflammation, membrane remodeling, and cancer
ART4 (731 words) [view diff] exact match in snippet view article find links to article
experimentally. Antigens of the Dombrock blood group system are located on the gene product, which is glycosylphosphatidylinositol-anchored to the erythrocyte membrane
SIX4 (455 words) [view diff] exact match in snippet view article find links to article
murine homeobox protein AREC3, a homologue of Drosophila sine oculis gene product, and implication in development". Nucleic Acids Res. 24 (2): 303–10.
Efflux pump (2,007 words) [view diff] exact match in snippet view article find links to article
aeruginosa is inducible by antibiotics that target ribosomes via the PA5471 gene product. Efflux pumps have also been shown to play a role in biofilm formation
MecA (2,473 words) [view diff] exact match in snippet view article find links to article
genome. That structure is conserved between the mecA gene product and a homologous mecA gene product in Staphylococcus sciuri. As of 2007, function for
Protein subunit (781 words) [view diff] exact match in snippet view article find links to article
Rendering of HLA-A11 showing the α (A*1101 gene product) and β (Beta-2 microglobulin) subunits. This receptor has a bound peptide (in the binding pocket)
PDE4A (1,373 words) [view diff] exact match in snippet view article find links to article
human phosphodiesterases homologous to the dunce learning and memory gene product of Drosophila melanogaster are potential targets for antidepressant drugs"
Kinesin-like protein KIF11 (7,112 words) [view diff] exact match in snippet view article find links to article
of spindle dynamics and essential for mitosis. The function of this gene product includes chromosome positioning, centrosome separation and establishing
DUSP5 (553 words) [view diff] exact match in snippet view article find links to article
modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1/2, is expressed in a variety of tissues with the highest
SNRPG (1,144 words) [view diff] exact match in snippet view article find links to article
DEAD box protein that interacts with SMN, the spinal muscular atrophy gene product, and is a component of gems". J. Cell Biol. 147 (6): 1181–94. doi:10
VCAM-1 (789 words) [view diff] exact match in snippet view article find links to article
known RNA transcripts that encode different isoforms in humans. The gene product is a cell surface sialoglycoprotein, a type I membrane protein that is
Mucin 2 (316 words) [view diff] exact match in snippet view article find links to article
Library of Medicine. Allen A, Hutton DA, Pearson JP (July 1998). "The MUC2 gene product: a human intestinal mucin". Int. J. Biochem. Cell Biol. 30 (7): 797–801
40S ribosomal protein S13 (1,008 words) [view diff] exact match in snippet view article find links to article
cytoplasm. The protein has been shown to bind to the 5.8S rRNA in rat. The gene product of the E. coli ortholog (ribosomal protein S15) functions at early steps
HNRNPR (1,425 words) [view diff] exact match in snippet view article find links to article
"Specific interaction of Smn, the spinal muscular atrophy determining gene product, with hnRNP-R and gry-rbp/hnRNP-Q: a role for Smn in RNA processing in
Collagenase (753 words) [view diff] exact match in snippet view article find links to article
collagenases.[citation needed] Analysis of the primary structure of the gene product from Clostridium perfringens has revealed that the enzyme is produced
DinI-like protein family (207 words) [view diff] exact match in snippet view article find links to article
co-protease activity of RecA. Escherichia coli DinI, a LexA-regulated SOS gene product, shuts off the initiation of the SOS response when overexpressed in vivo
Woolly monkey sarcoma virus (395 words) [view diff] case mismatch in snippet view article find links to article
Demonstration that its Acquired Cellular Sequences Encode the Transforming Gene Product p28sis, JSTOR 13744, PMC 393453 E. P. Gelmannn, E. Petri, A. Cetta, F
MutationTaster (679 words) [view diff] exact match in snippet view article find links to article
battery of in silico tests to estimate the impact of the variant on the gene product / protein. Tests are made on both, protein and DNA level, MutationTaster
Fibroblast growth factor receptor-like 1 (842 words) [view diff] exact match in snippet view article find links to article
influencing mitogenesis and differentiation. A marked difference between this gene product and the other family members is its lack of a cytoplasmic tyrosine kinase
Genetic marker (985 words) [view diff] exact match in snippet view article find links to article
into two classes: a) biochemical markers which detect variation at the gene product level such as changes in proteins and amino acids and b) molecular markers
Exonuclease (1,752 words) [view diff] exact match in snippet view article find links to article
epsilon-subunit of Escherichia coli DNA polymerase III holoenzyme as the dnaQ gene product: a fidelity subunit for DNA replication". Proc Natl Acad Sci U S A. 80
RAD23A (1,482 words) [view diff] exact match in snippet view article find links to article
Kotliarova S, Kanazawa I, Nukina N (July 2000). "Ataxin-3, the MJD1 gene product, interacts with the two human homologs of yeast DNA repair protein RAD23
Goa (disambiguation) (538 words) [view diff] exact match in snippet view article
capital Gene ontology Annotation, the practice of capturing data about a gene product General of the army, a military rank used in some countries to denote
ZNF43 (602 words) [view diff] exact match in snippet view article find links to article
development, and are quite conserved throughout evolution. Like this gene product, a third of the zinc finger proteins containing C2H2 fingers also contain
TEAD3 (590 words) [view diff] exact match in snippet view article find links to article
TEF-5 is a protein that in humans is encoded by the TEAD3 gene. This gene product is a member of the transcriptional enhancer factor (TEF) family of transcription
EIF4G2 (1,118 words) [view diff] exact match in snippet view article find links to article
which supports cap-dependent and independent translation, the eIF4G2 gene product functions as a general repressor of translation by forming translationally
PKD2L1 (712 words) [view diff] exact match in snippet view article find links to article
and cellular localization of a novel polycystic kidney disease-like gene product, polycystin-L". J. Am. Soc. Nephrol. 13 (2): 293–301. doi:10.1681/ASN
MCL1 (1,490 words) [view diff] exact match in snippet view article find links to article
The longer gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene product (isoform 2) promotes
EIF3S6 (1,091 words) [view diff] exact match in snippet view article find links to article
(October 1999). "Interaction between the Ret finger protein and the Int-6 gene product and co-localisation into nuclear bodies". J. Cell Sci. 112 ( Pt 19) (19):
EIF3C (1,078 words) [view diff] exact match in snippet view article find links to article
P (1999). "Interaction between the Ret finger protein and the Int-6 gene product and co-localisation into nuclear bodies". J. Cell Sci. 112 ( Pt 19) (19):
NDEL1 (2,014 words) [view diff] exact match in snippet view article find links to article
interacts with Lis1, regulating the activity of the dynein complex. This gene product is a thiol-activated oligopeptidase and is also known as Endooligopeptidase
HLA-DQ8 (5,460 words) [view diff] exact match in snippet view article find links to article
determined by the antibody recognition of β8 and this generally detects the gene product of DQB1*0302. DQ8 is commonly linked to autoimmune disease in the human
LSM2 (1,309 words) [view diff] exact match in snippet view article find links to article
DEAD box protein that interacts with SMN, the spinal muscular atrophy gene product, and is a component of gems". The Journal of Cell Biology. 147 (6): 1181–94
Steroidogenic factor 1 (3,478 words) [view diff] exact match in snippet view article find links to article
development of embryonic gonads into testes or ovaries is activated by the SRY gene product. Sexual differentiation is then directed by hormones produced by embryonic
MMP24 (620 words) [view diff] exact match in snippet view article find links to article
Koshikawa N, Miyamori H, et al. (2003). "Cleavage of metastasis suppressor gene product KiSS-1 protein/metastin by matrix metalloproteinases". Oncogene. 22 (30):
PHLDA1 (616 words) [view diff] exact match in snippet view article find links to article
"Inhibition of protein synthesis by the T cell receptor-inducible human TDAG51 gene product". Cell. Signal. 13 (5). England: 345–52. doi:10.1016/S0898-6568(01)00141-3
FANCF (2,441 words) [view diff] exact match in snippet view article find links to article
Hoatlin ME, Joenje H, de Winter JP (September 2004). "The Fanconi anemia gene product FANCF is a flexible adaptor protein". The Journal of Biological Chemistry
Cyclin-dependent kinase 4 (3,555 words) [view diff] exact match in snippet view article find links to article
the kinase is responsible for the phosphorylation of retinoblastoma gene product (Rb). The Ser/Thr-kinase component of cyclin D-CDK4 (DC) forms complexes
TYRP1 (2,071 words) [view diff] exact match in snippet view article find links to article
humans is encoded by the TYRP1 gene. Tyrp1 is a melanocyte-specific gene product involved in melanin synthesis within melanosomes. Most Tyrp1 possess
Transcription coregulator (1,039 words) [view diff] exact match in snippet view article find links to article
which information from a gene is used in the synthesis of a functional gene product such as a protein transcription – the process of making messenger RNA
Perennial (2,728 words) [view diff] exact match in snippet view article find links to article
associated with large increases in expression of two DNA repair genes (one gene product a photolyase and the other, a protein involved in nucleotide excision
Knockout mouse (1,889 words) [view diff] exact match in snippet view article find links to article
for both the neomycin resistance gene and the herpes tk+ gene, whose gene product reacts with Ganciclovir to produce a deadly toxin. Moreover, cells that
ACADSB (1,142 words) [view diff] exact match in snippet view article find links to article
characteristic used to define members of this gene family. The ACADSB gene product has the greatest activity towards the short branched chain acyl-CoA derivative
MAGI1 (1,322 words) [view diff] exact match in snippet view article find links to article
Kleiderlein JJ, Sharp AH, Ross CA (Jun 1998). "Atrophin-1, the DRPLA gene product, interacts with two families of WW domain-containing proteins". Molecular
B3GAT1 (1,391 words) [view diff] exact match in snippet view article find links to article
recognizing nonreducing terminal sugars and their anomeric linkages. This gene product functions as the key enzyme in a glucuronyl transfer reaction during
Autotaxin (1,692 words) [view diff] exact match in snippet view article find links to article
responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells, has angiogenic properties, and
Adenomatous polyposis coli (3,225 words) [view diff] exact match in snippet view article find links to article
(August 1994). "Association of plakoglobin with APC, a tumor suppressor gene product, and its regulation by tyrosine phosphorylation". Biochemical and Biophysical
MLX (gene) (974 words) [view diff] exact match in snippet view article
play a role in proliferation, determination and differentiation. This gene product may act to diversify Mad family function by its restricted association
UBE2E1 (752 words) [view diff] exact match in snippet view article find links to article
Kang S (Jun 2008). "UbcH6 interacts with and ubiquitinates the SCA1 gene product ataxin-1". Biochem. Biophys. Res. Commun. 371 (2): 256–60. doi:10.1016/j
PDGFB (434 words) [view diff] exact match in snippet view article find links to article
mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the
RAD23B (1,848 words) [view diff] exact match in snippet view article find links to article
Kotliarova S, Kanazawa I, Nukina N (Jul 2000). "Ataxin-3, the MJD1 gene product, interacts with the two human homologs of yeast DNA repair protein RAD23
CD68 (1,369 words) [view diff] exact match in snippet view article find links to article
cell tumor: immunohistochemical assessment of inhibin-alpha, protein gene product 9.5, S100 protein, CD68, and Ki-67 proliferative index with clinical
DOK1 (1,385 words) [view diff] exact match in snippet view article find links to article
Mosialos G, Kieff E (June 2000). "The X-linked lymphoproliferative syndrome gene product SH2D1A associates with p62dok (Dok1) and activates NF-kappa B". Proc
Gary Ruvkun (3,189 words) [view diff] exact match in snippet view article find links to article
the key regulatory element of the lin-14 gene recognized by the lin-4 gene product was in the lin-14 3’ untranslated region came from the analysis of lin-14
TEAD4 (1,017 words) [view diff] exact match in snippet view article find links to article
TEF-3 is a protein that in humans is encoded by the TEAD4 gene. This gene product is a member of the transcriptional enhancer factor (TEF) family of transcription
Complement factor B (1,095 words) [view diff] exact match in snippet view article find links to article
complement protein factor B, a class III major histocompatibility complex gene product". Proceedings of the National Academy of Sciences of the United States
Hol118 family (384 words) [view diff] exact match in snippet view article find links to article
(AUG-3) at nucleotide position 40 in the gene gives rise to a second gene product of 83 aas lacking TMS-1 (Hol118(83)). It is produced with the full length
Glycoside hydrolase family 48 (491 words) [view diff] exact match in snippet view article find links to article
thermophilic anaerobic bacterium Caldocellum saccharolyticum. The celA gene product is a polypeptide of 1751 amino acids; this has a multidomain structure
Transferrin receptor 1 (937 words) [view diff] exact match in snippet view article find links to article
VK, Lebrón JA, Watson N, et al. (February 1998). "The hemochromatosis gene product complexes with the transferrin receptor and lowers its affinity for ligand
PHC1 (1,006 words) [view diff] exact match in snippet view article find links to article
The gene product is a component of a multimeric protein complex that contains EDR2 and the vertebrate Polycomb protein BMI1. The gene product, the EDR2
1987 in science (939 words) [view diff] exact match in snippet view article find links to article
phosphatase isozyme conversion in Escherichia coli, and identification of the gene product". Journal of Bacteriology. 169 (12): 5429–33. doi:10.1128/jb.169.12.5429-5433
Functional genomics (4,013 words) [view diff] exact match in snippet view article find links to article
"biochemical, cellular, and/or physiological properties of each and every gene product" while some authors include the study of nongenic elements in their definition
CHAF1A (1,132 words) [view diff] exact match in snippet view article find links to article
2004). "Physical and functional interaction between the Bloom's syndrome gene product and the largest subunit of chromatin assembly factor 1". Mol. Cell. Biol
CD6 (1,219 words) [view diff] exact match in snippet view article find links to article
binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. Certain alleles of
David (disambiguation) (485 words) [view diff] exact match in snippet view article
States DAVID, a bioinformatics tool for high-throughput analysis of gene product functions DAVID (Digital Audio Video Interactive Decoder), a platform
Bloom syndrome (2,752 words) [view diff] exact match in snippet view article find links to article
mutations in components of the same protein complex to which the BLM gene product belongs, including TOP3A, which encodes the type I topoisomerase, topoisomerase
MID1 (2,218 words) [view diff] exact match in snippet view article find links to article
Suckow V, Muller YA, Walter G, et al. (March 1999). "The Opitz syndrome gene product, MID1, associates with microtubules". Proceedings of the National Academy
FGF6 (606 words) [view diff] exact match in snippet view article find links to article
F, Batoz M, Marics I, et al. (1991). "Putative structure of the FGF6 gene product and role of the signal peptide". Oncogene. 6 (8): 1437–44. PMID 1886714
Glycoside hydrolase family 48 (491 words) [view diff] exact match in snippet view article find links to article
thermophilic anaerobic bacterium Caldocellum saccharolyticum. The celA gene product is a polypeptide of 1751 amino acids; this has a multidomain structure
PAG1 (653 words) [view diff] exact match in snippet view article find links to article
PMID 11684085. S2CID 12676563. Wen ST, Van Etten RA (October 1997). "The PAG gene product, a stress-induced protein with antioxidant properties, is an Abl SH3-binding
SPTBN1 (997 words) [view diff] exact match in snippet view article find links to article
cerebellar Purkinje-cell bodies and interacts with neurofibromatosis type 2 gene product schwannomin". J. Mol. Neurosci. 17 (1): 59–70. doi:10.1385/JMN:17:1:59
DUSP4 (835 words) [view diff] exact match in snippet view article find links to article
modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues
SPP1 (76 words) [view diff] exact match in snippet view article find links to article
USSR firearm made for Soviet frogmen Secreted phosphoprotein 1, a human gene product Suppressor of Pericarp Pigmentation 1, a maize gene implied in the phlobaphene
EIF2AK1 (1,113 words) [view diff] exact match in snippet view article find links to article
from opposite strands. Studies in rat and rabbit suggest that the HRI gene product phosphorylates the alpha subunit of eukaryotic initiation factor 2. Its
NFYC (1,102 words) [view diff] exact match in snippet view article find links to article
to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit C, forms a tight dimer with the B subunit (NFYB), a prerequisite
HOXB5 (1,048 words) [view diff] exact match in snippet view article find links to article
"Cooperative DNA binding of the highly conserved human Hox 2.1 homeodomain gene product". The New Biologist. 4 (5): 558–68. PMID 1355360. Peverali FA, D'Esposito
E4F1 (1,192 words) [view diff] exact match in snippet view article find links to article
differentially regulated by E1A-induced phosphorylation. The full-length gene product represses transcription from the E4 promoter in the absence of E1A, while
PHOX2A (1,038 words) [view diff] exact match in snippet view article find links to article
paired-like homeodomain most similar to that of the Drosophila aristaless gene product. This protein is expressed specifically in noradrenergic cell types.
Neurofibromatosis type II (3,350 words) [view diff] exact match in snippet view article find links to article
DH, Lal A (November 2008). "The neurofibromatosis 2 tumor suppressor gene product, merlin, regulates human meningioma cell growth by signaling through
Ribonuclease E (2,251 words) [view diff] exact match in snippet view article find links to article
McDowall KJ, Cohen SN (January 1996). "The N-terminal domain of the rne gene product has RNase E activity and is non-overlapping with the arginine-rich RNA-binding
Tyrosine-protein kinase Fes/Fps (577 words) [view diff] exact match in snippet view article find links to article
feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required
Fanconi anemia, complementation group C (2,397 words) [view diff] exact match in snippet view article find links to article
Hoatlin ME, Joenje H, de Winter JP (Sep 2004). "The Fanconi anemia gene product FANCF is a flexible adaptor protein". The Journal of Biological Chemistry
RABEP1 (1,213 words) [view diff] exact match in snippet view article find links to article
F, Jin F, Golemis EA, Yeung RS (Mar 1997). "The tuberous sclerosis 2 gene product, tuberin, functions as a Rab5 GTPase activating protein (GAP) in modulating
HCCS (gene) (1,014 words) [view diff] exact match in snippet view article
Y, Oda H, Munakata K, Goto Y, Ohta S (2005). "MIDAS/GPP34, a nuclear gene product, regulates total mitochondrial mass in response to mitochondrial dysfunction"
SIPA1 (723 words) [view diff] exact match in snippet view article find links to article
PMID 8889548. Kurachi H, Wada Y, Tsukamoto N, et al. (1997). "Human SPA-1 gene product selectively expressed in lymphoid tissues is a specific GTPase-activating
Bacterial morphological plasticity (3,631 words) [view diff] exact match in snippet view article find links to article
two-component signal transduction system, leading to inactivation of the ftsL gene product, penicillin binding protein 3 (PBP-3). The ftsL gene is a group of filamentation
Aprataxin (1,511 words) [view diff] exact match in snippet view article find links to article
Taylor AM, Caldecott KW (November 2004). "The ataxia-oculomotor apraxia 1 gene product has a role distinct from ATM and interacts with the DNA strand break
P-glycoprotein (3,930 words) [view diff] exact match in snippet view article find links to article
P-glycoprotein was solved (3G5U). The structure was derived from the mouse MDR3 gene product heterologously expressed in Pichia pastoris yeast. The structure of mouse
MMP16 (982 words) [view diff] exact match in snippet view article find links to article
Koshikawa N, Miyamori H (2003). "Cleavage of metastasis suppressor gene product KiSS-1 protein/metastin by matrix metalloproteinases". Oncogene. 22 (30):
Sense strand (502 words) [view diff] exact match in snippet view article find links to article
sense and antisense is relative to perspective). It is ultimately the gene product, or mRNA, that dictates which strand of one segment of dsDNA we call
Protein ZGRF1 (1,714 words) [view diff] exact match in snippet view article find links to article
gene also known as C4orf21, that has a weight of 236.6 kDa. The ZGRF1 gene product localizes to the cell nucleus and promotes DNA repair by stimulating
STAU1 (2,556 words) [view diff] exact match in snippet view article find links to article
that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the
40S ribosomal protein S27 (1,369 words) [view diff] exact match in snippet view article find links to article
Fernandez-Pol JA, Klos DJ, Hamilton PD (Aug 1994). "Metallopanstimulin gene product produced in a baculovirus expression system is a nuclear phosphoprotein
Morquio syndrome (1,017 words) [view diff] exact match in snippet view article find links to article
syndrome or MPS IVA and MPS IVB. The two forms are distinguished by the gene product involved; Type A involves a malfunction in the GALNS gene, while Type
Leukocyte receptor tyrosine kinase (857 words) [view diff] exact match in snippet view article find links to article
Hanai N, Yazaki Y, Hirai H (1993). "Identification of the human ltk gene product in placenta and hematopoietic cell lines". Biochem. Biophys. Res. Commun
Microviridae (2,393 words) [view diff] exact match in snippet view article find links to article
Uchiyama A, Fane BA (2007) Eliminating the requirement of an essential gene product in an already very small virus: scaffolding protein B-free øX174, B-free"
BNIP3L (880 words) [view diff] exact match in snippet view article find links to article
J, Oren M, Amson R, Telerman A (Mar 2003). "The p53-inducible TSAP6 gene product regulates apoptosis and the cell cycle and interacts with Nix and the
MAGI2 (944 words) [view diff] exact match in snippet view article find links to article
Kleiderlein J J; Sharp A H; Ross C A (Jun 1998). "Atrophin-1, the DRPLA gene product, interacts with two families of WW domain-containing proteins". Mol.
MLH1 (3,414 words) [view diff] exact match in snippet view article find links to article
Hickson ID, Jackson SP (August 2001). "Cleavage of the Bloom's syndrome gene product during apoptosis by caspase-3 results in an impaired interaction with
Lentivirus (1,771 words) [view diff] exact match in snippet view article find links to article
carbohydrates. Lentivirus is primarily a research tool used to introduce a gene product into in vitro systems or animal models. Large-scale collaborative efforts
TLL1 (510 words) [view diff] exact match in snippet view article find links to article
Brevard R, Hoffman GG, et al. (1997). "Characterization of a novel gene product (mammalian tolloid-like) with high sequence similarity to mammalian tolloid/bone
ATRX (1,758 words) [view diff] exact match in snippet view article find links to article
Colleaux L (April 1998). "Specific interaction between the XNP/ATR-X gene product and the SET domain of the human EZH2 protein". Human Molecular Genetics
FANCG (2,456 words) [view diff] exact match in snippet view article find links to article
Hoatlin ME, Joenje H, de Winter JP (September 2004). "The Fanconi anemia gene product FANCF is a flexible adaptor protein" (PDF). J. Biol. Chem. 279 (38):
ING1 (1,536 words) [view diff] exact match in snippet view article find links to article
Chen YT (Dec 1999). "Cancer-testis antigens and ING1 tumor suppressor gene product are breast cancer antigens: characterization of tissue-specific ING1
IKZF3 (1,215 words) [view diff] exact match in snippet view article find links to article
transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte
NFYB (1,235 words) [view diff] exact match in snippet view article find links to article
to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for
Protein AATF (1,226 words) [view diff] exact match in snippet view article find links to article
kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription
PDE4B (1,442 words) [view diff] exact match in snippet view article find links to article
human phosphodiesterases homologous to the dunce learning and memory gene product of Drosophila melanogaster are potential targets for antidepressant drugs"
Tyrosine-protein kinase CSK (977 words) [view diff] exact match in snippet view article find links to article
subunit of protein kinase A). Csk's interaction with a phosphatase ("Lyp", gene product of PTPN22) is possibly associated with the increased autoimmune diseases
COMMD1 (892 words) [view diff] exact match in snippet view article find links to article
PMID 12547404. Tao TY, Liu F, Klomp L, et al. (2004). "The copper toxicosis gene product Murr1 directly interacts with the Wilson disease protein". J. Biol. Chem
GRIA2 (3,304 words) [view diff] exact match in snippet view article find links to article
are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to
Abemaciclib (1,467 words) [view diff] exact match in snippet view article find links to article
Wang NP, Qian YW, Lee EY, Lee WH (October 1991). "The retinoblastoma gene product regulates progression through the G1 phase of the cell cycle". Cell.
TRPC1 (978 words) [view diff] exact match in snippet view article find links to article
Kim E, Walz G, Sukhatme VP (Mar 1999). "Specific association of the gene product of PKD2 with the TRPC1 channel". Proceedings of the National Academy
MST1R (1,088 words) [view diff] exact match in snippet view article find links to article
Wang MH, Ronsin C, Gesnel MC, et al. (1994). "Identification of the ron gene product as the receptor for the human macrophage stimulating protein". Science
SERPINI2 (628 words) [view diff] exact match in snippet view article find links to article
coagulation, fibrinolysis, development, malignancy and inflammation. The gene product may have a role in a growth-control, possibly growth-suppressing pathway
AIR synthetase (FGAM cyclase) (578 words) [view diff] exact match in snippet view article
Atkins CA (April 1998). "AIR synthetase in cowpea nodules: a single gene product targeted to two organelles?". Plant Mol. Biol. 36 (6): 811–20. doi:10
UBE2V1 (921 words) [view diff] exact match in snippet view article find links to article
protein consisting of sequence sharing identity with each individual gene product. UBE2V1 has been shown to interact with UBE2N. GRCh38: Ensembl release
THOC1 (867 words) [view diff] exact match in snippet view article find links to article
H (November 1994). "The amino-terminal region of the retinoblastoma gene product binds a novel nuclear matrix protein that co-localizes to centers for
NUDC (1,087 words) [view diff] exact match in snippet view article find links to article
Albrecht U, Reiner O, Eichele G, Yu-Lee LY (May 1998). "The lissencephaly gene product Lis1, a protein involved in neuronal migration, interacts with a nuclear
RUNX1T1 (1,732 words) [view diff] exact match in snippet view article find links to article
(2000). "Atrophin-1, the dentato-rubral and pallido-luysian atrophy gene product, interacts with ETO/MTG8 in the nuclear matrix and represses transcription"
Diagnosis of HIV/AIDS (5,753 words) [view diff] no match in snippet view article find links to article
for each of the GAG, POL, and ENV gene-product groups are present, the result is positive. The three-gene-product approach to western blot interpretation
RAP1GAP (998 words) [view diff] exact match in snippet view article find links to article
Kubota H, Hattori M, Iwai K, Minato N (October 1997). "Human SPA-1 gene product selectively expressed in lymphoid tissues is a specific GTPase-activating
Methylcobalamin (997 words) [view diff] exact match in snippet view article find links to article
of alkylcobalamins in mammalian cells: A role for the MMACHC (cblC) gene product". Molecular Genetics and Metabolism. 97 (4): 260–266. doi:10.1016/j.ymgme
CSTX (587 words) [view diff] exact match in snippet view article find links to article
amino acids having a size of 6708 Da. CSTX-2a is a variation of the same gene product, and it differs from CSTX-1 only on the last 13 amino acids of the C-terminal
Arxula adeninivorans (590 words) [view diff] exact match in snippet view article find links to article
activated upon binding. In this case a gene sequence of a reporter gene (the gene product can be easily monitored by simple assays) was fused to a control sequence
WWP2 (1,225 words) [view diff] exact match in snippet view article find links to article
Kleiderlein JJ, Sharp AH, Ross CA (June 1998). "Atrophin-1, the DRPLA gene product, interacts with two families of WW domain-containing proteins". Mol.
Calcitonin receptor (1,446 words) [view diff] exact match in snippet view article find links to article
activity-modifying protein interaction with the calcitonin receptor gene product". Molecular Pharmacology. 56 (1): 235–242. doi:10.1124/mol.56.1.235.
Ganciclovir (864 words) [view diff] exact match in snippet view article find links to article
data Bioavailability 5% (oral) Metabolism guanylate kinase (CMV UL97 gene product) Elimination half-life 2.5–5 hours Excretion Kidney Identifiers IUPAC
PAX5 (1,433 words) [view diff] exact match in snippet view article find links to article
has also been detected in developing CNS and testis, therefore, PAX5 gene product may not only play an important role in B-cell differentiation, but also
Melatonin receptor 1B (1,644 words) [view diff] exact match in snippet view article find links to article
for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane
Electrogenic sodium bicarbonate cotransporter 1 (1,216 words) [view diff] exact match in snippet view article find links to article
pancreas and elsewhere) NBCe1-C (expressed in the brain) The renal SLC4A4 gene product NBCe1-A is specifically expressed in the basolateral membranes of proximal
Chloride anion exchanger (1,139 words) [view diff] exact match in snippet view article find links to article
Gregor M, Seidler U (October 2002). "The down regulated in adenoma (dra) gene product binds to the second PDZ domain of the NHE3 kinase A regulatory protein
2-Hydroxymuconate-6-semialdehyde dehydrogenase (240 words) [view diff] exact match in snippet view article find links to article
benzaldehyde dehydrogenase (the xylC gene product) and 2-hydroxymuconic semialdehyde dehydrogenase (the xylG gene product) encoded by TOL plasmid pWW0 of Pseudomonas
RELB (1,560 words) [view diff] exact match in snippet view article find links to article
Park S, Ryseck RP, et al. (February 1992). "A novel mitogen-inducible gene product related to p50/p105-NF-kappa B participates in transactivation through
KDM5A (1,598 words) [view diff] exact match in snippet view article find links to article
"Cloning of cDNAs for cellular proteins that bind to the retinoblastoma gene product". Nature. 352 (6332): 251–4. Bibcode:1991Natur.352..251D. doi:10.1038/352251a0
Fusion gene (1,928 words) [view diff] exact match in snippet view article find links to article
high-grade serous ovarian cancer. Oncogenic fusion genes may lead to a gene product with a new or different function from the two fusion partners. Alternatively
TAL1 (1,404 words) [view diff] exact match in snippet view article find links to article
PMID 1311214. Aplan PD, Nakahara K, Orkin SH, Kirsch IR (1992). "The SCL gene product: a positive regulator of erythroid differentiation". EMBO J. 11 (11):
NFYA (1,466 words) [view diff] exact match in snippet view article find links to article
addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation
SMN1 (1,274 words) [view diff] exact match in snippet view article find links to article
F, Dreyfuss G (September 1997). "The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal
Interleukin-6 receptor (1,438 words) [view diff] exact match in snippet view article find links to article
"Functional murine interleukin 6 receptor with the intracisternal A particle gene product at its cytoplasmic domain. Its possible role in plasmacytomagenesis"
UBE2N (1,070 words) [view diff] exact match in snippet view article find links to article
human ubiquitin-conjugating enzyme similar to the Drosophila bendless gene product". J Biochem. 120 (3): 494–97. doi:10.1093/oxfordjournals.jbchem.a021440
Cre recombinase (1,745 words) [view diff] exact match in snippet view article find links to article
showed that a P1 gene product and a recombination site were both required for efficient recombination events to occur. The P1 gene product was named Cre
TOB1 (1,287 words) [view diff] exact match in snippet view article find links to article
protein with the v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 gene product p185 interferes with growth suppression. This protein inhibits T cell
Progeroid syndromes (8,748 words) [view diff] exact match in snippet view article find links to article
of its gene product is also unclear. Mutations in the TTDN1 gene explain another 10% of non-photosensitive TTD. The function of the gene product of TTDN1
Zamilon virophage (1,211 words) [view diff] exact match in snippet view article find links to article
function 1 111 none – – 2 73 none – – 3 135 Megavirus chilensis mg3 gene product 67 – 4 221 Sputnik virophage 2 putative IS3 family transposase A protein
HLA-B52 (633 words) [view diff] exact match in snippet view article find links to article
Serotypes B52, B5, B51, and B53 recognition of HLA B*5201 gene product B*52 B52 B5 B51 B53 Sample allele % % % % size (N) *5201 84 2 7 1 2823 Alleles link-out
DUSP1 (1,185 words) [view diff] exact match in snippet view article find links to article
CH, Lau LF, Tonks NK (Nov 1993). "MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in
BCR (gene) (1,541 words) [view diff] exact match in snippet view article
fusion protein has been much studied, the function of the normal BCR gene product is still not clear. The protein has serine/threonine kinase activity
DUSP6 (1,178 words) [view diff] exact match in snippet view article find links to article
modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest
INVS (808 words) [view diff] exact match in snippet view article find links to article
S2CID 4972004. Simons M, Gloy J, Ganner A, et al. (2005). "Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch
CDKN2B (1,386 words) [view diff] exact match in snippet view article find links to article
sequence but completely differ in the C-terminus. CDKN2B tumor suppressor gene product p15 has been shown to interact with cyclin-dependent kinase 4. GRCh38:
Extramacrochaetae (738 words) [view diff] exact match in snippet view article find links to article
difference between concentrations of the scute gene product, which is on the X-chromosome, and the emc gene product, which is on an autosomal chromosome. Specifically
KvLQT1 (1,503 words) [view diff] exact match in snippet view article find links to article
required for the repolarization phase of the cardiac action potential. The gene product can form heteromultimers with two other potassium channel proteins, KCNE1
MAGEA1 (938 words) [view diff] exact match in snippet view article find links to article
S2CID 11331427. Schultz-Thater E, Juretic A, Dellabona P, et al. (1994). "MAGE-1 gene product is a cytoplasmic protein". Int. J. Cancer. 59 (3): 435–9. doi:10.1002/ijc
PRKCH (1,139 words) [view diff] exact match in snippet view article find links to article
J, Shimon T, et al. (1992). "The protein kinase C-related PKC-L(eta) gene product is localized in the cell nucleus". Mol. Cell. Biol. 12 (3): 1304–11.
HLA-DQ (2,596 words) [view diff] exact match in snippet view article find links to article
a dimer containing two protein subunits, alpha (DQA1 gene product) and beta (DQB1 gene product), a DQ heterodimer. These receptors can be made from alpha+beta
CYP2A6 (1,131 words) [view diff] exact match in snippet view article find links to article
PMID 1944238. Yamano S, Tatsuno J, Gonzalez FJ (1990). "The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes". Biochemistry
Ventromedial nucleus of the hypothalamus (1,818 words) [view diff] exact match in snippet view article find links to article
Nakao K (March 1997). "Pathophysiological significance of the obese gene product, leptin, in ventromedial hypothalamus (VMH)-lesioned rats: evidence for
PTCH1 (1,629 words) [view diff] exact match in snippet view article find links to article
tumorigenesis. This gene functions as a tumor suppressor. The PTCH1 gene product, is a transmembrane protein that suppresses the release of another protein
Dynamin-like 120 kDa protein (2,081 words) [view diff] exact match in snippet view article find links to article
a poison exon between exons 5 and 6 or between exons 5b and 6. This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related
FANCB (1,025 words) [view diff] exact match in snippet view article find links to article
severity is associated with the extent of residual activity. The FANCB gene product is FANCB protein. FANCB is a component of a "core complex" of nine Fanconi
Histatin (796 words) [view diff] exact match in snippet view article find links to article
3 through the process of post-translational proteolysis of the HTN3 gene product. Therefore there are only two genes, HTN1 and HTN3. The N-terminus of
Gideon Dreyfuss (1,130 words) [view diff] exact match in snippet view article find links to article
Wang, F.; Dreyfuss, G. (1997). "The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal
DDB2 (2,071 words) [view diff] exact match in snippet view article find links to article
association of XRCC5/6 in the absence of DNA damage depends on the XPE gene product DDB2". Molecular Biology of the Cell. 28 (1): 192–200. doi:10.1091/mbc
Ronald J. Konopka (1,727 words) [view diff] exact match in snippet view article find links to article
dissipates during the subjective night. The model predicts that the per gene product is active during the subjective day and functions like a pump to establish
RBBP8 (1,867 words) [view diff] exact match in snippet view article find links to article
WH (July 2000). "Functional link of BRCA1 and ataxia telangiectasia gene product in DNA damage response". Nature. 406 (6792): 210–5. doi:10.1038/35018134
ELAC2 (1,265 words) [view diff] exact match in snippet view article find links to article
(September 2006). "ELAC2, a putative prostate cancer susceptibility gene product, potentiates TGF-beta/Smad-induced growth arrest of prostate cells".
Michael W. Young (1,858 words) [view diff] exact match in snippet view article find links to article
Michael Young (1986). "Changes in the abundance or structure of the per gene product can affect the periodicity of the Drosophila clock". Nature. 326 (6111):
KIR2DS4 (1,387 words) [view diff] case mismatch in snippet view article find links to article
(February 2007). "Studies on the Expression of the Deleted KIR2DS4*003 Gene Product and Distribution of KIR2DS4 Deleted and Nondeleted Versions in Different
Morphogenesis (2,724 words) [view diff] no match in snippet view article find links to article
wild-type and amber mutants and their possible implications as to type of gene-product function: Catalytic vs. Stoichiometric". Virology. 35 (4): 550–563. doi:10
LITAF (958 words) [view diff] exact match in snippet view article find links to article
et al. (2004). "PIG7/LITAF gene mutation and overexpression of its gene product in extramammary Paget's disease". Int. J. Cancer. 111 (2): 218–23. doi:10
TAS2R14 (1,957 words) [view diff] exact match in snippet view article find links to article
heart, thyroid, stomach, skin, urogenital, immune system, and more. This gene product belongs to the family of taste receptors that are members of the G-protein-coupled
Epitope (2,566 words) [view diff] exact match in snippet view article find links to article
resulting epitope tag allows the antibody to find the protein or other gene product enabling lab techniques for localisation, purification, and further molecular
PDSS2 (732 words) [view diff] exact match in snippet view article find links to article
or ubiquinone, one of the key elements in the respiratory chain. The gene product catalyzes the formation of all trans-polyprenyl pyrophosphates from isopentyl
HLA-DQB2 (948 words) [view diff] exact match in snippet view article find links to article
(1997). "The enhanced immune response to the HIV gp160/LAMP chimeric gene product targeted to the lysosome membrane protein trafficking pathway". J. Biol
Cadherin related family member 3 (812 words) [view diff] exact match in snippet view article find links to article
"Cadherin-related family member 3, a childhood asthma susceptibility gene product, mediates rhinovirus C binding and replication". Proceedings of the National
Visna-maedi virus (3,774 words) [view diff] exact match in snippet view article find links to article
The function of the auxiliary gene vif is not fully known. The vif gene product, a 29 kDa protein, induces a weak immune response in animals. Deletion
Cell adhesion molecule 1 (1,186 words) [view diff] exact match in snippet view article find links to article
(2003). "Promoter methylation of TSLC1 and tumor suppression by its gene product in human prostate cancer". Jpn. J. Cancer Res. 93 (6): 605–9. doi:10
MAP3K3 (1,820 words) [view diff] exact match in snippet view article find links to article
gene, which is located on the long arm of chromosome 17 (17q23.3). This gene product is a 626-amino acid polypeptide that is 96.5% identical to mouse MEKK3
PDGFC (1,369 words) [view diff] exact match in snippet view article find links to article
origin and are characterized by a core motif of eight cysteines. This gene product appears to form only homodimers. It differs from the platelet-derived
Subcloning (631 words) [view diff] exact match in snippet view article find links to article
contains regulatory elements allowing for the bacteria to produce a gene product (gene expression) if it is placed in the correct place in the plasmid
HAND2 (2,023 words) [view diff] exact match in snippet view article find links to article
to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins Hand1
Mitochondrial neurogastrointestinal encephalopathy syndrome (800 words) [view diff] exact match in snippet view article find links to article
POLIP syndrome Structure of thymidine phosphorylase enzyme, the main gene product of the TYMP gene. Mutations in the TYMP gene result in the loss of function
Kim Nasmyth (1,578 words) [view diff] exact match in snippet view article find links to article
characterising cell cycle mutants and the first identification of a gene product (DNA ligase) in these mutants. Nasmyth joined Ben Hall's lab in Seattle
Rhinovirus (3,278 words) [view diff] exact match in snippet view article find links to article
"Cadherin-related family member 3, a childhood asthma susceptibility gene product, mediates rhinovirus C binding and replication". Proceedings of the National
Caldococcus (990 words) [view diff] exact match in snippet view article find links to article
weight of the gene product was about 48,000. This estimate was consistent with an estimate from the deduced amino acid sequence. The gene product also displayed
Utrophin (1,241 words) [view diff] exact match in snippet view article find links to article
Ellis JM, et al. (1991). "Tissue distribution of the dystrophin-related gene product and expression in the mdx and dy mouse". Proc. Natl. Acad. Sci. U.S.A
ELOC (1,663 words) [view diff] exact match in snippet view article find links to article
protein (VBP-1) binding to the von Hippel-Lindau (VHL) tumor suppressor gene product". Cancer Res. 56 (13): 2881–5. PMID 8674032. Min JH, Yang H, Ivan M,
Biphenotypic acute leukaemia (1,904 words) [view diff] exact match in snippet view article find links to article
11q23. T(9;22) affect the ABL gene at 9q34 and BCR at 22q11. The hybrid gene product ABL/BCR is an oncogene which could lead several types of leukemia including
TAF1 (2,422 words) [view diff] exact match in snippet view article find links to article
Ruppert S, Robbins PD (April 1995). "The retinoblastoma-susceptibility gene product binds directly to the human TATA-binding protein-associated factor TAFII250"
CD244 (1,912 words) [view diff] exact match in snippet view article find links to article
(April 2002). "Association of the X-linked lymphoproliferative disease gene product SAP/SH2D1A with 2B4, a natural killer cell-activating molecule, is dependent
List of histologic stains that aid in diagnosis of cutaneous conditions (254 words) [view diff] exact match in snippet view article find links to article
(PTAH) Infantile digital fibromatosis Pogoda red Amyloidosis Protein gene product 9.5 (PGP9.5) Nerve sheath myxoma Silver nitrate Urate crystal Gout Sirius
NK2 homeobox 1 (2,118 words) [view diff] exact match in snippet view article find links to article
ras downstream pathways mediate functional repression of the homeobox gene product TTF-1". Molecular and Cellular Biology. 20 (8): 2783–93. doi:10.1128/MCB
Neutrophil collagenase (196 words) [view diff] exact match in snippet view article find links to article
Mainardi CL (July 1990). "Human neutrophil collagenase. A distinct gene product with homology to other matrix metalloproteinases". The Journal of Biological
Activating transcription factor 2 (2,261 words) [view diff] exact match in snippet view article find links to article
S, Liu F, O'Reilly MA, Robbins PD, Green MR (1992). "Retinoblastoma gene product activates expression of the human TGF-beta 2 gene through transcription
HD5 (94 words) [view diff] exact match in snippet view article find links to article
00h 05m 10.1829s; +02° 23′ 49.949″) Human Alpha Defensin 5, the DEFA5 gene product This disambiguation page lists articles associated with the same title
Jeffrey C. Hall (2,075 words) [view diff] exact match in snippet view article find links to article
Rosbash, Michael (February 8, 1990). "Feedback of the Drosophila period gene product on circadian cycling of its messenger RNA levels". Nature. 343 (6258):
Barth syndrome (1,717 words) [view diff] exact match in snippet view article find links to article
or NG_009634) is highly expressed in cardiac and skeletal muscle; its gene product, Taz1p, functions as an acyltransferase in complex lipid metabolism.
IRX1 (2,041 words) [view diff] exact match in snippet view article find links to article
5, from position 3596054 - 3601403 at the 5p15.3 location. The human gene product is a 1858 base pair mRNA with 4 predicted exons in humans. Promoter analysis
Virus latency (2,070 words) [view diff] exact match in snippet view article find links to article
more copies of the infected cell to be produced. An example of such a gene product is the latency associated transcripts (LAT) in herpes simplex virus,
KCNE5 (1,859 words) [view diff] exact match in snippet view article find links to article
(originally named KCNE1-L) that has sequence similarity to the KCNE1 gene product, a member of the potassium channel, voltage-gated, isk-related subfamily
HAND1 (2,187 words) [view diff] exact match in snippet view article find links to article
to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins are expressed
Chilblain lupus erythematosus (1,470 words) [view diff] exact match in snippet view article find links to article
causes apoptotic ss-DNA damage, which is mediated in part by the TREX1 gene product. Granzyme A-mediated cell death was substantially less effective in heterozygous
ArgJ protein family (156 words) [view diff] exact match in snippet view article find links to article
ArgJ ornithine acetyltransferase (orf6 gene product - clavulanic acid biosynthesis) from streptomyces clavuligerus Identifiers Symbol ArgJ Pfam PF01960
Polycystin 2 (1,206 words) [view diff] exact match in snippet view article find links to article
Kim E, Walz G, Sukhatme VP (March 1999). "Specific association of the gene product of PKD2 with the TRPC1 channel". Proceedings of the National Academy
Morphogen (1,863 words) [view diff] exact match in snippet view article find links to article
transcription of the gene and thus controls the level of expression of the gene product (usually a protein). 'Low-threshold' target genes require only low levels
Lisa Coussens (1,011 words) [view diff] exact match in snippet view article find links to article
factor-beta, adenovirus12-E1A, and by the retinoblastoma susceptibility gene product. OCLC 732921603. "Lisa M. Coussens M.D. (h.c.), Ph.D., FAACR | OHSU People
Pseudotyping (728 words) [view diff] exact match in snippet view article find links to article
prevented from infecting cells and producing the luminescent reporter gene product. When analysed, cell culture samples where an effective inhibitor of
Lawrence B. Salkoff (1,566 words) [view diff] exact match in snippet view article find links to article
mutations where the gene product is absent or non-functional, gain of function mutations where the functional properties of the gene product is changed, and
GNAS complex locus (1,696 words) [view diff] exact match in snippet view article find links to article
PHP1B. XLαs (Extra long alpha-s, Q5JWF2), paternal ALEX (Alternative gene product encoded by XL-exon, P84996), may inhibit XLαs NESP55 (Neuroendocrine
Proteome (3,013 words) [view diff] no match in snippet view article find links to article
Duncan MW, Harris R, Williams KL, Humphery-Smith I (1995). "Progress with gene-product mapping of the Mollicutes: Mycoplasma genitalium". Electrophoresis. 16
Ankyrin-3 (1,738 words) [view diff] exact match in snippet view article find links to article
protein encoded by this gene, ankyrin-3 is an immunologically distinct gene product from ankyrins ANK1 and ANK2, and was originally found at the axonal initial
TSC2 (1,786 words) [view diff] exact match in snippet view article find links to article
the TSC2 gene. Mutations in this gene lead to tuberous sclerosis. Its gene product is believed to be a tumor suppressor and is able to stimulate specific
NDUFA13 (1,912 words) [view diff] exact match in snippet view article find links to article
Runswick MJ, Walker JE, Hirst J (2001). "GRIM-19, a cell death regulatory gene product, is a subunit of bovine mitochondrial NADH:ubiquinone oxidoreductase
Neurofibromatosis type I (7,077 words) [view diff] exact match in snippet view article find links to article
cloning of the type 1 neurofibromatosis gene: complete sequence of the NF1 gene product". Genomics. 11 (4): 931–940. doi:10.1016/0888-7543(91)90017-9. hdl:2027
Pulmonary alveolar proteinosis (2,309 words) [view diff] exact match in snippet view article find links to article
receptor alpha is located in the 5q31 region of chromosome 5, and the gene product can also be referred to as granulocyte macrophage colony-stimulating
PEX16 (774 words) [view diff] exact match in snippet view article find links to article
Zellweger syndrome of the complementation group CGD/CG9. Expression of this gene product morphologically and biochemically restores the formation of new peroxisomes
Battenin (1,268 words) [view diff] exact match in snippet view article find links to article
Chataway TK, Sutherland GR, Callen DF (March 1999). "The Batten disease gene product (CLN3p) is a Golgi integral membrane protein". Human Molecular Genetics
Hfq protein (1,117 words) [view diff] no match in snippet view article find links to article
Schumacher MA1, Pearson RF, Møller T, Valentin-Hansen P, Brennan RG. hfq+Gene+Product at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
XPA (1,437 words) [view diff] exact match in snippet view article find links to article
(Oct 1991). "Identification and characterization of xpac protein, the gene product of the human XPAC (xeroderma pigmentosum group A complementing) gene"
ABL2 (1,464 words) [view diff] exact match in snippet view article find links to article
ABL2 gene is higher in KRAS mutant non-small cell lung cancer. The ABL2 gene product is expressed as two variants bearing different amino termini, both approximately
GRIA3 (2,077 words) [view diff] exact match in snippet view article find links to article
rise to the necessarily high diversity of these receptors. GluR3 is a gene product of the GRIA3 gene and its pre-mRNA is subject to RNA editing. A to I
PRDX3 (1,206 words) [view diff] exact match in snippet view article find links to article
Salmonella typhimurium alkylhydroperoxide reductase. Expression of this gene product in E. coli deficient in the C22-subunit gene rescued resistance of the
Tumor suppressor gene (3,409 words) [view diff] exact match in snippet view article find links to article
two-hit rule for tumor suppressors, such as certain mutations in the p53 gene product. p53 mutations can function as a dominant negative, meaning that a mutated
Epidermal growth factor (1,708 words) [view diff] exact match in snippet view article find links to article
This section is missing information about the entire 1207-aa long gene product: the pro-pre-EGF; what happens if things go wrong (renal hypomagnesemia
Netrin receptor DCC (5,119 words) [view diff] exact match in snippet view article find links to article
Snipas SJ, Assa-Munt N, Salvesen GS, Bredesen DE (October 1998). "The DCC gene product induces apoptosis by a mechanism requiring receptor proteolysis". Nature
HNF1A (2,614 words) [view diff] case mismatch in snippet view article find links to article
PDB gallery 1ic8: HEPATOCYTE NUCLEAR FACTOR 1A BOUND TO DNA : MODY3 GENE PRODUCT 1lfb: THE X-RAY STRUCTURE OF AN ATYPICAL HOMEODOMAIN PRESENT IN THE RAT
Tumor marker (1,850 words) [view diff] exact match in snippet view article find links to article
prognosis and measure how the patient responds to treatment, while genes or gene product can be analyzed to identify mutations in the genome or altered gene expression
Adaptive response (1,187 words) [view diff] exact match in snippet view article find links to article
activated, which is a consequence of the DNA repair activity. The alkA gene product is a glycosylase that can repair a variety of lesions, removing a base
Recombinant DNA (3,852 words) [view diff] exact match in snippet view article find links to article
encountered include toxicity to the host organism induced by the recombinant gene product, especially if it is over-expressed or expressed within inappropriate
Isochorismate synthase (440 words) [view diff] exact match in snippet view article find links to article
Populus angustifolia Populus tremuloides ICS1 Arabidopsis thaliana ICS1 gene product Arabidopsis thaliana Cyanidium caldarium ICS2 Arabidopsis thaliana Isochorismate
5-HT4 receptor (2,074 words) [view diff] exact match in snippet view article find links to article
cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral
Homeobox protein Nkx-2.5 (2,325 words) [view diff] exact match in snippet view article find links to article
site within the homeodomain of the cardiac tisue-specifying homeobox gene product Csx/Nkx2.5". Molecular and Cellular Biology. 19 (1): 526–36. doi:10.1128/mcb
FLNA (1,903 words) [view diff] exact match in snippet view article find links to article
protein (VBP-1) binding to the von Hippel-Lindau (VHL) tumor suppressor gene product". Cancer Res. 56 (13): 2881–5. PMID 8674032. Zhou MI, Wang H, Ross JJ
Michael Stuart Brown (3,286 words) [view diff] exact match in snippet view article find links to article
geranylgeranyl transferase: possible identity with the choroideremia gene product". Cell. 70 (6): 1049–57. doi:10.1016/0092-8674(92)90253-9. PMID 1525821
Adrenocortical carcinoma (2,065 words) [view diff] exact match in snippet view article find links to article
cortisol and aldosterone. Also, a loss occurs of activity of the p57kip2 gene product in virilizing adenomas and adrenal cortical carcinomas. In contrast,
UBE2V2 (1,677 words) [view diff] exact match in snippet view article find links to article
homology with ubiquitin-conjugating enzyme E2 variant 1 and yeast MMS2 gene product. UBE2V2 has also been implicated as an intracellular sensor of reactive
Maturity-onset diabetes of the young (2,494 words) [view diff] exact match in snippet view article find links to article
cases, there are significant differences in the activity of the mutant gene product that contribute to variations in the clinical features of the diabetes
CYP3A5 (1,959 words) [view diff] exact match in snippet view article find links to article
(June 1989). "Cytochrome P-450 hPCN3, a novel cytochrome P-450 IIIA gene product that is differentially expressed in adult human liver. cDNA and deduced
Alport syndrome (2,436 words) [view diff] exact match in snippet view article find links to article
network. Skin biopsies have been used to show the absence of the COL4A5 gene product, but these techniques are not straightforward, only apply to patients
STK11 (2,831 words) [view diff] exact match in snippet view article find links to article
Odze RD, Zhou XC, Zhu H, Shaw R, et al. (June 2001). "The Peutz-Jegher gene product LKB1 is a mediator of p53-dependent cell death". Molecular Cell. 7 (6):
Expressivity (genetics) (1,763 words) [view diff] exact match in snippet view article
expressivity of the FBN1 gene found on chromosome 15 (see figure 2). The gene product is involved in the proper assembly of microfibrils, which are structures
Renpenning's syndrome (340 words) [view diff] exact match in snippet view article find links to article
commonly occur. It is associated with mutations in the PQBP1 gene. The gene product is a polyglutamine-binding protein involved in transcription and pre-mRNA
Michael Rosbash (2,781 words) [view diff] exact match in snippet view article find links to article
Hall, J. C.; Rosbash, M. (1990). "Feedback of the Drosophila period gene product on circadian cycling of its messenger RNA levels". Nature. 343 (6258):
Kinetic logic (3,101 words) [view diff] exact match in snippet view article find links to article
rate of synthesis of the element. Thus, x = 0 means "gene product absent" x = 1 means "gene product present" & X = 0 means "gene off" X = 1 means "gene
Pertuzumab (2,276 words) [view diff] exact match in snippet view article find links to article
reactive to either the human epidermal growth factor receptor or HER2/neu gene product" (PDF). Cancer Research. 50 (5): 1550–1558. PMID 1689212. Archived (PDF)
CCHCR1 (1,771 words) [view diff] exact match in snippet view article find links to article
cytoplasm by its interaction with HCR, the psoriasis vulgaris candidate gene product". J. Cell Sci. 118 (Pt 18): 4253–60. doi:10.1242/jcs.02545. PMID 16141233
HLA-DOA (984 words) [view diff] exact match in snippet view article find links to article
(1997). "The enhanced immune response to the HIV gp160/LAMP chimeric gene product targeted to the lysosome membrane protein trafficking pathway". J. Biol
Janus kinase 1 (2,423 words) [view diff] exact match in snippet view article find links to article
"Through induction of juxtaposition and tyrosine kinase activity of Jak1, X-gene product of hepatitis B virus stimulates Ras and the transcriptional activation
ARID4B (492 words) [view diff] exact match in snippet view article find links to article
differentiation, apoptosis, oncogenesis, and cell fate determination. The gene product is recognized by IgG antibody isolated from a breast cancer patient and
Tellurium ion resistance (708 words) [view diff] exact match in snippet view article find links to article
C.; Cho, M.H. (2008). "Deletion of the chloroplast-localized AtTerC gene product in Arabidopsis thaliana leads to loss of the thylakoid membrane and to
Chaperone (protein) (3,501 words) [view diff] no match in snippet view article
wild-type and amber mutants and their possible implications as to type of gene-product function: catalytic vs. stoichiometric. Virology. 1968;35(4):550-563
GRIA4 (2,008 words) [view diff] exact match in snippet view article find links to article
This give rise to the necessary diversity of the receptors. GluR4 is a gene product of the GRIA4 gene, and its pre-mRNA is subject to RNA editing. A to I
Epithelial stromal interaction 1 (247 words) [view diff] exact match in snippet view article find links to article
valosin containing protein gene product, resulting in the nuclear translocation of the nuclear factor kappa B subunit 1 gene product, and activation of target
CCDC85B (548 words) [view diff] exact match in snippet view article find links to article
those of plant viroids. Delta-interacting protein A (DIPA), a cellular gene product, has been found to have homology to hepatitis delta virus antigen (HDAg)
Megalencephalic leukoencephalopathy with subcortical cysts (1,370 words) [view diff] exact match in snippet view article find links to article
start codon in exon 2 and an untranslated region in the 3’ end. The MLC1 gene product is a 377 amino acid protein highly expressed in the brain. The disease
Catenin (3,618 words) [view diff] exact match in snippet view article find links to article
formation that includes β-catenin, AXIN1, AXIN2, APC (a tumor suppressor gene product), CSNK1A1, and GSK3B. Following phosphorylation of the N-terminal Ser
Furin (2,288 words) [view diff] exact match in snippet view article find links to article
de Ven WJ (February 1990). "Structural homology between the human fur gene product and the subtilisin-like protease encoded by yeast KEX2". Nucleic Acids