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searching for Pseudotyping 8 found (14 total)

Vectors in gene therapy (4,912 words) [view diff] no match in snippet view article find links to article

Gene therapy utilizes the delivery of DNA into cells, which can be accomplished by several methods, summarized below. The two major classes of methods

Adeno-associated virus (8,517 words) [view diff] exact match in snippet view article find links to article

tissue types. Tissue specificity is determined by the capsid serotype and pseudotyping of AAV vectors to alter their tropism range will likely be important

Reporter virus particles (1,073 words) [view diff] exact match in snippet view article find links to article

allow study of the later stages of the viral life cycle. RVPs formed by pseudotyping contain the native form of the viral Envelope (or Spike) protein, but

Retrograde tracing (1,211 words) [view diff] exact match in snippet view article find links to article

can be limited to monosynaptic transmission to a neuron of origin by pseudotyping the G protein and putting the gene under Cre-control. This viral spread

Klaus Cichutek (1,017 words) [view diff] exact match in snippet view article find links to article

K. Proc Natl Acad Sci U S A. 1994 Jan 18; 91(2):654-8. PMID 8290577 Pseudotyping of murine leukemia virus with the envelope glycoproteins of HIV generates

James E. K. Hildreth (948 words) [view diff] exact match in snippet view article find links to article

assembly and entry, proposed HIV-1 as a Trojan exosome, and natural pseudotyping enables HIV-1 to directly infect epithelial barrier cells in the female

RNA silencing (5,470 words) [view diff] exact match in snippet view article find links to article

mildly immunogenic, lasting expression in non-dividing cells, capsid pseudotyping/engineering facilitates specific cell-targeting Lentivirus Up to 13.5

Lentiviral vector in gene therapy (3,334 words) [view diff] exact match in snippet view article find links to article

self-inactivating plasmids and creating a more universal tropism by pseudotyping a vesicular stomatitis virus glycoprotein. In chronic granulomatous disease