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Find link is a tool written by Edward Betts.searching for MLH1 31 found (100 total)
alternate case: mLH1
Endometrial intraepithelial neoplasia
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PMID 7585555. Esteller M, Catasus L, Matias-Guiu X, et al. (November 1999). "hMLH1 promoter hypermethylation is an early event in human endometrial tumorigenesis"Field cancerization (1,850 words) [view diff] exact match in snippet view article find links to article
Park CS, Juhng SW, Lee JH (October 2011). "Promoter methylation status of hMLH1, hMSH2, and MGMT genes in colorectal cancer associated with adenoma-carcinomaChromosomal crossover (3,779 words) [view diff] exact match in snippet view article find links to article
crossovers in eukaryotes. The majority of them are repaired by MutL homologs MLH1 and MLH3, which defines the class I crossovers. The remaining are the resultShapiro–Senapathy algorithm (6,804 words) [view diff] exact match in snippet view article find links to article
ovarian cancer (e.g., SLC9A3R1, COL7A1, HSD17B7), colon cancer (e.g., APC, MLH1, DPYD), colorectal cancer (e.g., COL3A1, APC, HLA-A), skin cancer (e.g.,Richard Kolodner (635 words) [view diff] exact match in snippet view article find links to article
bacteria and yeast, Kolodner identified two DNA mismatch repair genes, MSH2 and MLH1, that lead to 95 percent of hereditary colon cancer cases. In both casesSebaceous carcinoma (3,254 words) [view diff] exact match in snippet view article find links to article
colorectal adenocarcinoma. MTS results from defects in DNA mismatch repair genes, MLH1, MSH2, and MSH6, leading to a buildup of unstable microsatellite sequencesList of genes mutated in cutaneous conditions (108 words) [view diff] exact match in snippet view article find links to article
(Wermer syndrome) Merlin Neurofibromatosis type 2 Merosin Infantile hemangioma MLH1 Muir–Torre syndrome MLPH Griscelli syndrome MITF Waardenburg syndrome typeCarcinoma (3,246 words) [view diff] case mismatch in snippet view article find links to article
genetic instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6". Carcinogenesis. 27 (12): 2402–2408. doi:10.1093/carcin/bgl079MAX (gene) (2,166 words) [view diff] exact match in snippet view article
et al. (February 2003). "Interactions of the DNA mismatch repair proteins MLH1 and MSH2 with c-MYC and MAX". Oncogene. 22 (6): 819–825. doi:10.1038/sj.oncCell damage (2,829 words) [view diff] case mismatch in snippet view article find links to article
genetic instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6". Carcinogenesis. 27 (12): 2402–2408. doi:10.1093/carcin/bgl079Dana–Farber Cancer Institute (2,337 words) [view diff] exact match in snippet view article find links to article
the risk for a common type of colon cancer. The MSH2 gene and later the MLH1 gene (also by DFCI investigators) are linked to hereditary nonpolyposis colorectalDeleted in lung and esophageal cancer 1 (699 words) [view diff] exact match in snippet view article find links to article
Sutherland RL, Kennedy C, McCaughan B, Kohonen-Corish MR (July 2008). "DLEC1 and MLH1 promoter methylation are associated with poor prognosis in non-small cellTemozolomide (2,971 words) [view diff] exact match in snippet view article find links to article
with temozolomide and then selection or induction of mutant MSH6, MSH2, MLH1, or PMS2 proteins and cells which are MMRd and temozolomide resistant. TheMUS81 (1,406 words) [view diff] exact match in snippet view article find links to article
J, Edelmann W, McGowan CH, Cohen PE (2008). "MUS81 generates a subset of MLH1-MLH3-independent crossovers in mammalian meiosis". PLOS Genet. 4 (9): e1000186Bert Vogelstein (3,828 words) [view diff] exact match in snippet view article find links to article
soon led them and other groups to identify repair genes such as MSH2 and MLH1 that are responsible for most cases of this syndrome. In the early 2000sPaula Cohen (717 words) [view diff] exact match in snippet view article find links to article
E. Cohen; M. Kane; et al. (28 June 1996). "Meiotic pachytene arrest in MLH1-deficient mice". Cell. 85 (7): 1125–1134. doi:10.1016/S0092-8674(00)81312-4Combined bisulfite restriction analysis (1,300 words) [view diff] exact match in snippet view article find links to article
PMID 16174854. Suter, Catherine, M.; et al. (2004). "Germline epimutation in MLH1 in individuals with multiple cancers". Nature Genetics. 36 (5): 497–501.Glioma (7,034 words) [view diff] case mismatch in snippet view article find links to article
genetic instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6". Carcinogenesis. 27 (12): 2402–8. doi:10.1093/carcin/bgl079Human genome (10,102 words) [view diff] exact match in snippet view article find links to article
nonpolyposis coli) 1:3500 APC Lynch syndrome 5–10% of all cases of bowel cancer MLH1, MSH2, MSH6, PMS2 Fanconi anemia 1:130000 births FANCC Neurological conditionsPeter Propping (1,403 words) [view diff] exact match in snippet view article find links to article
Mangold, . . . P. Propping: Spectrum and frequenciens of mutations in MSH2 and MLH1 in 1721 German families suspected of hereditary nonpolyposis colorectal cancerSynthetic lethality (2,804 words) [view diff] case mismatch in snippet view article find links to article
genetic instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6". Carcinogenesis. 27 (12): 2402–8. doi:10.1093/carcin/bgl079Male breast cancer (4,659 words) [view diff] exact match in snippet view article find links to article
Lynch syndrome with mutations in any of the four DNA mismatch repair genes (MLH1, MSH2, MSH6, PMS2), or the EpCAM gene. The relative risks of men vs. womenZygotene (650 words) [view diff] exact match in snippet view article find links to article
occurs between the non-sister chromatids. Key recombination proteins like MLH1/3 and MSH4/5 mark the sites of crossover formation. The number and positioningPachytene (888 words) [view diff] exact match in snippet view article find links to article
non-sister chromatids that were initiated during zygotene. Proteins like MLH1 and MLH3 stabilize the crossover events, ensuring at least one obligatoryMUTYH (2,955 words) [view diff] exact match in snippet view article find links to article
the interaction of Mismatch Repair proteins (MMR) such as MSH 2,3 and 6, MLH1, PMS1 and 2, and MUTYH in which the proposed result of their partnering isBristol LH (1,703 words) [view diff] exact match in snippet view article find links to article
Fleet numbers Registrations Type Built MLH1–19 SMS 671–678H, SWG 669–679H LH C38F 1970 MLH20–33 WMS 920J–925J, WWG 326J–333J LH C41F 1971 MLH34–38 BWG 334–338LTalazoparib (1,230 words) [view diff] exact match in snippet view article find links to article
inhibitor or docetaxel. HRR genes (ATM, ATR, BRCA1, BRCA2, CDK12, CHEK2, FANCA, MLH1, MRE11A, NBN, PALB2, or RAD51C) were assessed prospectively using tumor tissueRAD9A (3,997 words) [view diff] exact match in snippet view article find links to article
have a number of key interactions with mismatch repair protein complexes MLH1, MSH2, MSH3, and MSH6. Also, it has known interaction in the following repairPOLD1 (7,954 words) [view diff] exact match in snippet view article find links to article
example, germline mutations in DNA repair proteins involved in MMR (MSH2, MLH1, MSH6, and PMS2) have been described in Lynch syndrome (LS), which is characterizedSarah Tabrizi (3,638 words) [view diff] exact match in snippet view article find links to article
Sarah J. (August 2021). "FAN1 controls mismatch repair complex assembly via MLH1 retention to stabilize CAG repeat expansion in Huntington's disease". CellUnstable DNA sequence (2,187 words) [view diff] exact match in snippet view article find links to article
A., Peltomäki, P. (1 May 2000). "Genetic and epigenetic modification of MLH1 accounts for a major share of Microsatellite-Unstable colorectal cancers"