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Longer titles found: Caspase 10 (view), Caspase 11 (view), Caspase 12 (view), Caspase 13 (view), Caspase 14 (view), Caspase 16, pseudogene (view)

searching for caspase 1 49 found (112 total)

alternate case: Caspase 1

NLRP2 (1,498 words) [view diff] no match in snippet view article find links to article

an N-terminal pyrin domain (PYD) and are involved in the activation of caspase-1 (CASP1; MIM 147678) by Toll-like receptors(see TLR4). They may also be

NLRP7 (642 words) [view diff] no match in snippet view article find links to article

PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing". J Biol Chem. 277 (33): 29874–80. doi:10

COP1 (386 words) [view diff] case mismatch in snippet view article find links to article

"Cop, a caspase recruitment domain-containing protein and inhibitor of caspase-1 activation processing". J Biol Chem. 276 (37): 34495–500. doi:10.1074/jbc

NLRP12 (1,453 words) [view diff] no match in snippet view article find links to article

PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing". J Biol Chem. 277 (33): 29874–80. doi:10

Early 35 kDa protein (1,249 words) [view diff] no match in snippet view article find links to article

equilibrium state. In insect cells, P35 inhibits an enzyme called Sf caspase-1, which was identified as a structural and functional ortholog of human

Inhibitor of apoptosis (1,524 words) [view diff] exact match in snippet view article find links to article

caspases and preventing inflammatory responses and apoptosis. By inhibiting caspase 1, also known as interleukin 1β converting enzyme (ICE), crmA prevents cytokines

NLRP1 (2,089 words) [view diff] no match in snippet view article find links to article

responsible for the recruitment and activation of pro-caspase-1 in the active form of caspase-1. Human NLRP1 activation can be elicited by several means

NLRP4 (515 words) [view diff] no match in snippet view article find links to article

PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing". J Biol Chem. 277 (33): 29874–80. doi:10

RIPK2 (965 words) [view diff] no match in snippet view article find links to article

1998). "Identification of CARDIAK, a RIP-like kinase that associates with caspase-1". Curr Biol. 8 (15): 885–8. Bibcode:1998CBio....8..885T. doi:10

Rab (G-protein) (1,327 words) [view diff] no match in snippet view article

Small-scale transport, promoter for tumor development RAB27 Extracellular vesicles, endosome RAB29 Recruits LRRK2 to TGN RAB39A Binds Caspase-1 in inflammasome

Early-onset Alzheimer's disease (3,621 words) [view diff] no match in snippet view article find links to article

neuroinflammation of rats with Alzheimer's disease via regulating the SP1/BACE1/NLRP3/Caspase-1 signaling pathway". Bosnian Journal of Basic Medical Sciences. 22 (4):

Resiquimod (569 words) [view diff] no match in snippet view article find links to article

antibodies show synergistic effects on the induction of IL-1beta and caspase-1 in monocytes and dendritic cells". Immunobiology. 214 (8): 683–691. doi:10

Resiquimod (569 words) [view diff] no match in snippet view article find links to article

antibodies show synergistic effects on the induction of IL-1beta and caspase-1 in monocytes and dendritic cells". Immunobiology. 214 (8): 683–691. doi:10

Asymptomatic carrier (2,261 words) [view diff] no match in snippet view article find links to article

"The Salmonella invasin SipB induces macrophage apoptosis by binding to caspase-1". Proceedings of the National Academy of Sciences. 96 (5): 2396–2401.

IL18R1 (1,003 words) [view diff] no match in snippet view article find links to article

MR, et al. (2003). "Interleukin-1F7B (IL-1H4/IL-1F7) is processed by caspase-1 and mature IL-1F7B binds to the IL-18 receptor but does not induce IFN-gamma

PTPN2 (1,206 words) [view diff] no match in snippet view article find links to article

(2003). "A nuclear protein tyrosine phosphatase activates p53 and induces caspase-1-dependent apoptosis". FEBS Lett. 532 (1–2): 61–6. doi:10.1016/S0014-5793(02)03628-1

IFT57 (531 words) [view diff] no match in snippet view article find links to article

Bhattacharyya NP (2007). "Interaction of HIPPI with putative promoter sequence of caspase-1 in vitro and in vivo". Biochem. Biophys. Res. Commun. 353 (1): 80–5. doi:10

SERPINB9 (1,045 words) [view diff] no match in snippet view article find links to article

27802. PMID 8910377. Annand RR, Dahlen JR, Sprecher CA, et al. (1999). "Caspase-1 (interleukin-1beta-converting enzyme) is inhibited by the human serpin

Salmonellosis (6,758 words) [view diff] no match in snippet view article find links to article

recognize flagellin and activate NLRC4 inflammasome complex to activate caspase-1 and IL-1β and IL-18 release. Recruited monocytes are specifically adapted

Vermistatin (103 words) [view diff] no match in snippet view article find links to article

7164/antibiotics.39.1605. PMID 3793630. Stierle AA, Stierle DB, Girtsman T (2012). "Caspase-1 inhibitors from an extremophilic fungus that target specific leukemia

William Bachovchin (1,320 words) [view diff] no match in snippet view article find links to article

Bachovchin, W. W.; Bachovchin, D. A. (2016). "DPP8/9 inhibition induces pro-caspase-1-dependent monocyte and macrophage pyroptosis". Nature Chemical Biology

Myxoma virus (1,006 words) [view diff] no match in snippet view article find links to article

inhibit the caspases by binding to the CARD protein, which is part of the caspase-1-activating inflammasome complex. By binding, it is able to inhibit apoptosis

TNFRSF12A (2,216 words) [view diff] no match in snippet view article find links to article

TNFRSF12A promotes bile acid-induced hepatocyte pyroptosis through NFκB/Caspase-1/GSDMD signaling in cholestasis". Cell Death Discovery. 9 (1): 26. doi:10

Lysosome (4,709 words) [view diff] no match in snippet view article find links to article

Disrupts Lysosome Acidification in Systemic Lupus Erythematosus by Impairing Caspase-1 Cleavage of Rab39a". Journal of Immunology. 201 (2): 371–382. doi:10.4049/jimmunol

Mevalonate kinase deficiency (1,889 words) [view diff] no match in snippet view article find links to article

acts an inducer of IL-1β mRNA transcription independent of NLRP3- or caspase-1 activity. Due to defective RhoA there is a formation of defective mitochondria

NOD1 (937 words) [view diff] no match in snippet view article find links to article

enhances pro-interleukin-1beta processing through the interaction with pro-caspase-1". Biochemical and Biophysical Research Communications. 299 (4): 652–8

Baculoviral IAP repeat-containing protein 2 (1,879 words) [view diff] no match in snippet view article find links to article

(1998). "Identification of CARDIAK, a RIP-like kinase that associates with caspase-1". Curr. Biol. 8 (15): 885–8. doi:10.1016/S0960-9822(07)00352-1. PMID 9705938

Caspase recruitment domain-containing protein 8 (566 words) [view diff] no match in snippet view article find links to article

et al. (2002). "CARD-8 protein, a new CARD family member that regulates caspase-1 activation and apoptosis". J. Biol. Chem. 277 (16): 13952–8. doi:10.1074/jbc

Cornus officinalis (1,353 words) [view diff] no match in snippet view article find links to article

chondrocyte pyroptosis. It inhibits matrix metalloproteinase-13 (MMP13), Caspase-1 and nod-like receptor protein-3 (NLRP3) expression in DMM mice and IL-1β-stimulated

Innate immune system (4,797 words) [view diff] no match in snippet view article find links to article

has some similarities to animal pyroptosis, such as a requirement of caspase-1-like proteolytic activity of VPEγ, a cysteine protease that regulates

HIV/AIDS research (5,105 words) [view diff] no match in snippet view article find links to article

Identifying pyroptosis may provide novel therapeutic opportunities targeting caspase-1, which controls the pyroptotic cell death pathway. Specifically, these

Signalosome (765 words) [view diff] no match in snippet view article find links to article

filamentous assemblies that elicit host defense inside cells by activating caspase-1 for cytokine maturation and cell death. Cliffe, Adam; Hamada, Fumihiko;

Minocycline (4,673 words) [view diff] no match in snippet view article find links to article

Ferrante RJ, Fink KB, Zhu S, et al. (July 2000). "Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model

Katherine A. Fitzgerald (907 words) [view diff] no match in snippet view article find links to article

Fitzgerald, Katherine A. (2009). "AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC". Nature. 458 (7237): 514–518. Bibcode:2009Natur

Immune system (13,493 words) [view diff] no match in snippet view article find links to article

(consisting of an NLR, the adaptor protein ASC, and the effector molecule pro-caspase-1) that form in response to cytosolic PAMPs and DAMPs, whose function is

Serpin (14,251 words) [view diff] no match in snippet view article find links to article

through inhibition of IL-1 and IL-18 processing by the cysteine protease caspase-1. In eukaryotes, a plant serpin inhibits both metacaspases and a papain-like

Penicillium solitum (1,078 words) [view diff] no match in snippet view article find links to article

Stierle, Andrea A.; Girtsman, Teri; McIntyre, Kyle; Nichols, Jesse (2012). "Caspase-1 and -3 Inhibiting Drimane Sesquiterpenoids from the Extremophilic Fungus

Gisou van der Goot (1,228 words) [view diff] no match in snippet view article find links to article

Laurence; Girardin, Stephen; Tschopp, Jurg; Van Der Goot, F. Gisou (2006). "Caspase-1 Activation of Lipid Metabolic Pathways in Response to Bacterial Pore-Forming

Fungal isolate (966 words) [view diff] no match in snippet view article find links to article

1021/np070421v. PMID 18163588. Stierle AA, Stierle DB, Girtsman T (2012). "Caspase-1 inhibitors from an extremophilic fungus that target specific leukemia

Janelle Ayres (1,361 words) [view diff] no match in snippet view article find links to article

Epithelial Cell Expulsion with Eicosanoid and IL-18 Release via Activation of Caspase-1 and -8. (2017) Immunity. 46(4):649-659. DOI: 10.1016/j.immuni.2017.03

Galectin-9 (2,159 words) [view diff] no match in snippet view article find links to article

(April 2003). "Galectin-9 induces apoptosis through the calcium-calpain-caspase-1 pathway". Journal of Immunology. 170 (7): 3631–6. doi:10.4049/jimmunol

TREM1 (2,762 words) [view diff] no match in snippet view article find links to article

N, Chen B, Wang Q, Zhao X, Chen J, Cheng N, Feng X (December 2017). "Caspase-1 cleaves PPARγ for potentiating the pro-tumor action of TAMs". Nature Communications

MTORC2 (3,678 words) [view diff] no match in snippet view article find links to article

Disrupts Lysosome Acidification in Systemic Lupus Erythematosus by Impairing Caspase-1 Cleavage of Rab39a". Journal of Immunology. 201 (2): 371–382. doi:10.4049/jimmunol

National Brain Research Centre (3,699 words) [view diff] no match in snippet view article find links to article

S-RBD- and Orf3a-induced extracellular HMGB1 release but also abrogated caspase-1 activation and rescued cell death. Benefits of anti-inflammatory properties

BNIP3 (2,672 words) [view diff] case mismatch in snippet view article find links to article

undergone autophagic cell death, occurring in the absence of apaf-1, caspase-1 or caspase 3, and without cytochrome c release. However, it still remains

Staci Bilbo (2,152 words) [view diff] no match in snippet view article find links to article

memory impairment after lipopolysaccharide in adulthood is prevented via caspase-1 inhibition. Journal of Neuroscience 25 (35), 8000-8009 Bilbo, SD, Bowers

Perfluorodecanoic acid (3,380 words) [view diff] no match in snippet view article find links to article

treatment. The PFDA-induced SREBP1 enhanced expression can be terminated by caspase-1 inhibitor and by siNLRP3. PFDA is resistant to hydrolysis, photolysis

Julio Licinio (4,628 words) [view diff] exact match in snippet view article find links to article

Elashoff, D.; McCann, S. M.; Licinio, J.; Wong, M.-L. (24 April 2007). "Caspase 1 deficiency reduces inflammation-induced brain transcription". Proceedings

Alzheimer's disease and COVID-19 (3,555 words) [view diff] no match in snippet view article find links to article

Once activated, NLRP3 will interact with two other proteins, ASC and pro-caspase-1, to form the inflammasome, a circular structure made of multiple copies