cells. The BNIP3 pathway involves mitochondrial release and nuclear translocation of the endonuclease G. It is not clear, however, that how BNIP3 interacts
this gene is a functional homolog of BNIP3, a proapoptotic protein. This protein may function simultaneously with BNIP3 and may play a role in tumor suppression
amino-terminal targeting signal. ACAA2 has been shown to be a functional BNIP3 binding partner, which provides a possible link between fatty acid metabolism
Aryl hydrocarbon receptor CLOCK CREBBP CRY1 EP300 EPAS1 HIF1A NPAS2 SUMO3 BNIP3 Arntl2 - Arntl2 (Bmal2) is a paralog of Arntl (Bmal1) that encodes for a
1999). "BNIP3alpha: a human homolog of mitochondrial proapoptotic protein BNIP3". Cancer Research. 59 (3): 533–7. PMID 9973195. Human BNIPL genome location
(1999). "BNIP3alpha: a human homolog of mitochondrial proapoptotic protein BNIP3". Cancer Res. 59 (3): 533–7. PMID 9973195. Wang HG, Pathan N, Ethell IM
prolonged activation of HIF-1α can upregulate pro-apoptotic genes like BNIP3 and NIX, triggering mitochondrial dysfunction and cell death. The reliance
cells overexpressing a dominant-negative mutant of a pro-apoptotic BNIP3 (TM-BNIP3) were largely resistant to Brevinin-2R treatment. These 25 amino acid
malignant glioma cells by up-regulation of mitochondrial cell death protein BNIP3. Oncogene 24: 980-91, 2005. PMID 15592527 Germano IM,Gracies JM, Weisz DJ
transplantation", published on Int Immunopharmacol. 2011 Expression of NOV and BNIP3 gene in mouse myelomonocytic leukemia and its significance 2011 Relationship