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Longer titles found: Caspase 10 (view), Caspase 11 (view), Caspase 12 (view), Caspase 13 (view), Caspase 14 (view), Caspase 16, pseudogene (view)

searching for Caspase 1 44 found (102 total)

alternate case: caspase 1

NLRP2 (1,575 words) [view diff] no match in snippet view article find links to article

an N-terminal pyrin domain (PYD) and are involved in the activation of caspase-1 (CASP1; MIM 147678) by Toll-like receptors(see TLR4). They may also be
COP1 (393 words) [view diff] case mismatch in snippet view article find links to article
"Cop, a caspase recruitment domain-containing protein and inhibitor of caspase-1 activation processing". J Biol Chem. 276 (37): 34495–500. doi:10.1074/jbc
NLRP7 (639 words) [view diff] no match in snippet view article find links to article
PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing". J Biol Chem. 277 (33): 29874–80. doi:10
Early 35 kDa protein (1,236 words) [view diff] no match in snippet view article find links to article
equilibrium state. In insect cells, P35 inhibits an enzyme called Sf caspase-1, which was identified as a structural and functional ortholog of human
NLRP11 (440 words) [view diff] no match in snippet view article find links to article
family members identifies PYPAF5 as a novel regulator of NF-kappaB and caspase-1". FEBS Lett. 530 (1–3): 73–8. doi:10.1016/S0014-5793(02)03416-6. PMID 12387869
Inhibitor of apoptosis (1,521 words) [view diff] exact match in snippet view article find links to article
caspases and preventing inflammatory responses and apoptosis. By inhibiting caspase 1, also known as interleukin 1β converting enzyme (ICE), crmA prevents cytokines
NLRP4 (512 words) [view diff] no match in snippet view article find links to article
PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing". J Biol Chem. 277 (33): 29874–80. doi:10
RIPK2 (962 words) [view diff] no match in snippet view article find links to article
1998). "Identification of CARDIAK, a RIP-like kinase that associates with caspase-1". Curr Biol. 8 (15): 885–8. doi:10.1016/S0960-9822(07)00352-1. PMID 9705938
NLRP1 (2,218 words) [view diff] no match in snippet view article find links to article
responsible for the recruitment and activation of pro-caspase-1 in the active form of caspase-1. Human NLRP1 activation can be elicited by several means
Rab (G-protein) (1,315 words) [view diff] no match in snippet view article
endoplasmic reticulum RAB25 small-scale transport, promoter for tumor development RAB29 recruits LRRK2 to TGN RAB39A binds Caspase-1 in inflammasome
IL18R1 (990 words) [view diff] no match in snippet view article find links to article
MR, et al. (2003). "Interleukin-1F7B (IL-1H4/IL-1F7) is processed by caspase-1 and mature IL-1F7B binds to the IL-18 receptor but does not induce IFN-gamma
Asymptomatic carrier (2,174 words) [view diff] no match in snippet view article find links to article
"The Salmonella invasin SipB induces macrophage apoptosis by binding to caspase-1". Proceedings of the National Academy of Sciences. 96 (5): 2396–2401.
Resiquimod (595 words) [view diff] no match in snippet view article find links to article
antibodies show synergistic effects on the induction of IL-1beta and caspase-1 in monocytes and dendritic cells". Immunobiology. 214 (8): 683–91. doi:10
Autoinflammatory diseases (2,106 words) [view diff] exact match in snippet view article find links to article
a cell. The sensors of the innate immunity help to activate caspase 1 from pro-caspase 1. When activated, it cleaves precursors of the pro-inflammatory
IFT57 (531 words) [view diff] no match in snippet view article find links to article
Bhattacharyya NP (2007). "Interaction of HIPPI with putative promoter sequence of caspase-1 in vitro and in vivo". Biochem. Biophys. Res. Commun. 353 (1): 80–5. doi:10
PTPN2 (1,085 words) [view diff] no match in snippet view article find links to article
(2003). "A nuclear protein tyrosine phosphatase activates p53 and induces caspase-1-dependent apoptosis". FEBS Lett. 532 (1–2): 61–6. doi:10.1016/S0014-5793(02)03628-1
Myxoma virus (1,025 words) [view diff] no match in snippet view article find links to article
inhibit the caspases by binding to the CARD protein, which is part of the caspase-1-activating inflammasome complex. By binding it is able to inhibit apoptosis
NLRP12 (647 words) [view diff] no match in snippet view article find links to article
PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing". J Biol Chem. 277 (33): 29874–80. doi:10
Vermistatin (103 words) [view diff] no match in snippet view article find links to article
7164/antibiotics.39.1605. PMID 3793630. Stierle AA, Stierle DB, Girtsman T (2012). "Caspase-1 inhibitors from an extremophilic fungus that target specific leukemia
SERPINB9 (1,041 words) [view diff] no match in snippet view article find links to article
27802. PMID 8910377. Annand RR, Dahlen JR, Sprecher CA, et al. (1999). "Caspase-1 (interleukin-1beta-converting enzyme) is inhibited by the human serpin
Cornus officinalis (1,339 words) [view diff] no match in snippet view article find links to article
chondrocyte pyroptosis. It inhibits matrix metalloproteinase-13 (MMP13), Caspase-1 and nod-like receptor protein-3 (NLRP3) expression in DMM mice and IL-1β-stimulated
NOD1 (931 words) [view diff] no match in snippet view article find links to article
enhances pro-interleukin-1beta processing through the interaction with pro-caspase-1". Biochemical and Biophysical Research Communications. 299 (4): 652–8
Lysosome (4,776 words) [view diff] no match in snippet view article find links to article
Disrupts Lysosome Acidification in Systemic Lupus Erythematosus by Impairing Caspase-1 Cleavage of Rab39a". Journal of Immunology. 201 (2): 371–382. doi:10.4049/jimmunol
Innate immune system (4,752 words) [view diff] no match in snippet view article find links to article
has some similarities to animal pyroptosis, such as a requirement of caspase-1-like proteolytic activity of VPEγ, a cysteine protease that regulates
Mevalonate kinase deficiency (1,879 words) [view diff] no match in snippet view article find links to article
acts an inducer of IL-1β mRNA transcription independent of NLRP3- or caspase-1 activity. Due to defective RhoA there is a formation of defective mitochondria
Signalosome (731 words) [view diff] no match in snippet view article find links to article
filamentous assemblies that elicit host defense inside cells by activating caspase-1 for cytokine maturation and cell death. Cliffe, Adam; Hamada, Fumihiko;
Caspase recruitment domain-containing protein 8 (566 words) [view diff] no match in snippet view article find links to article
et al. (2002). "CARD-8 protein, a new CARD family member that regulates caspase-1 activation and apoptosis". J. Biol. Chem. 277 (16): 13952–8. doi:10.1074/jbc
HIV/AIDS research (4,129 words) [view diff] no match in snippet view article find links to article
Identifying pyroptosis may provide novel therapeutic opportunities targeting caspase-1, which controls the pyroptotic cell death pathway. Specifically, these
Baculoviral IAP repeat-containing protein 2 (1,876 words) [view diff] no match in snippet view article find links to article
(1998). "Identification of CARDIAK, a RIP-like kinase that associates with caspase-1". Curr. Biol. 8 (15): 885–8. doi:10.1016/S0960-9822(07)00352-1. PMID 9705938
Minocycline (3,873 words) [view diff] no match in snippet view article find links to article
W, Vonsattel JP, Cha JH, Friedlander RM (2000). "Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model
Immune system (12,840 words) [view diff] no match in snippet view article find links to article
(consisting of an NLR, the adaptor protein ASC, and the effector molecule pro-caspase-1) that form in response to cytosolic PAMPs and DAMPs, whose function is
Katherine A. Fitzgerald (901 words) [view diff] no match in snippet view article find links to article
Fitzgerald, Katherine A. (2009). "AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC". Nature. 458 (7237): 514–518. Bibcode:2009Natur
Serpin (13,648 words) [view diff] no match in snippet view article find links to article
through inhibition of IL-1 and IL-18 processing by the cysteine protease caspase-1. In eukaryotes, a plant serpin inhibits both metacaspases and a papain-like
Penicillium solitum (936 words) [view diff] no match in snippet view article find links to article
Stierle, Andrea A.; Girtsman, Teri; McIntyre, Kyle; Nichols, Jesse (2012). "Caspase-1 and -3 Inhibiting Drimane Sesquiterpenoids from the Extremophilic Fungus
Janelle Ayres (1,341 words) [view diff] no match in snippet view article find links to article
Epithelial Cell Expulsion with Eicosanoid and IL-18 Release via Activation of Caspase-1 and -8. (2017) Immunity. 46(4):649-659. DOI: 10.1016/j.immuni.2017.03
Gisou van der Goot (1,225 words) [view diff] no match in snippet view article find links to article
Laurence; Girardin, Stephen; Tschopp, Jurg; Van Der Goot, F. Gisou (2006). "Caspase-1 Activation of Lipid Metabolic Pathways in Response to Bacterial Pore-Forming
Galectin-9 (2,141 words) [view diff] no match in snippet view article find links to article
(April 2003). "Galectin-9 induces apoptosis through the calcium-calpain-caspase-1 pathway". Journal of Immunology. 170 (7): 3631–6. doi:10.4049/jimmunol
Fungal isolate (923 words) [view diff] no match in snippet view article find links to article
1021/np070421v. PMID 18163588. Stierle AA, Stierle DB, Girtsman T (2012). "Caspase-1 inhibitors from an extremophilic fungus that target specific leukemia
TREM1 (2,541 words) [view diff] no match in snippet view article find links to article
Zhao, Xuyang; Chen, Jiajia; Cheng, Nan; Feng, Xiujing (December 2017). "Caspase-1 cleaves PPARγ for potentiating the pro-tumor action of TAMs". Nature Communications
MTORC2 (3,576 words) [view diff] no match in snippet view article find links to article
Disrupts Lysosome Acidification in Systemic Lupus Erythematosus by Impairing Caspase-1 Cleavage of Rab39a". Journal of Immunology. 201 (2): 371–382. doi:10.4049/jimmunol
National Brain Research Centre (3,723 words) [view diff] no match in snippet view article find links to article
S-RBD- and Orf3a-induced extracellular HMGB1 release but also abrogated caspase-1 activation and rescued cell death. Benefits of anti-inflammatory properties
BNIP3 (2,667 words) [view diff] case mismatch in snippet view article find links to article
undergone autophagic cell death, occurring in the absence of apaf-1, caspase-1 or caspase 3, and without cytochrome c release. However, it still remains
Staci Bilbo (2,146 words) [view diff] no match in snippet view article find links to article
memory impairment after lipopolysaccharide in adulthood is prevented via caspase-1 inhibition. Journal of Neuroscience 25 (35), 8000-8009 Bilbo, SD, Bowers
Julio Licinio (5,463 words) [view diff] exact match in snippet view article find links to article
Elashoff, D.; McCann, S. M.; Licinio, J.; Wong, M.-L. (24 April 2007). "Caspase 1 deficiency reduces inflammation-induced brain transcription". Proceedings