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Longer titles found: Huntingtin-associated protein 1 (view), Huntingtin-interacting protein 1 (view), Huntingtin Interacting Protein (view)

searching for Huntingtin 110 found (186 total)

alternate case: huntingtin

HIP1R (673 words) [view diff] exact match in snippet view article find links to article

Huntingtin-interacting protein 1-related protein is a protein that in humans is encoded by the HIP1R gene. GRCh38: Ensembl release 89: ENSG00000130787
IFT57 (531 words) [view diff] exact match in snippet view article find links to article
Nicholson DW (Feb 2002). "Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi". Nat. Cell Biol.
F8A1 (723 words) [view diff] exact match in snippet view article find links to article
40-kDa huntingtin-associated protein is a protein that in humans is encoded by the F8A1, F8A2, and F8A3 genes. F8A1 is contained entirely within intron
IWS1 (609 words) [view diff] exact match in snippet view article find links to article
for cell survival. It also recruits a SET2 histone methyltransferase (Huntingtin-interacting protein HYPB, also known as SETD2) to RNAPII during transcription
RNF2 (1,104 words) [view diff] exact match in snippet view article find links to article
proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess
KIF5C (468 words) [view diff] exact match in snippet view article find links to article
family member 5C". Engelender S, Sharp AH, Colomer V, et al. (1998). "Huntingtin-associated protein 1 (HAP1) interacts with the p150Glued subunit of dynactin"
GPRASP2 (494 words) [view diff] exact match in snippet view article find links to article
associated sorting protein 2". Horn SC, Lalowski M, Goehler H, et al. (2007). "Huntingtin interacts with the receptor sorting family protein GASP2". Journal of
DCTN1 (1,601 words) [view diff] exact match in snippet view article find links to article
Tokito MK, Lanahan A, Worley P, Holzbaur EL, Ross CA (December 1997). "Huntingtin-associated protein 1 (HAP1) interacts with the p150Glued subunit of dynactin"
G. Marius Clore (2,872 words) [view diff] exact match in snippet view article find links to article
oligomerization events and associated structures involving the protein encoded by huntingtin exon-1, which may provide a potential avenue for therapeutic intervention
NEUROD1 (1,238 words) [view diff] exact match in snippet view article find links to article
Gowan K, Lee JE (August 2003). "Stimulation of NeuroD activity by huntingtin and huntingtin-associated proteins HAP1 and MLK2". Proceedings of the National
PRPF40B (162 words) [view diff] exact match in snippet view article find links to article
Barnes GT, Srinidhi J, Chen J, Gusella JF, MacDonald ME (Sep 1998). "Huntingtin interacts with a family of WW domain proteins". Human Molecular Genetics
RAB8A (1,080 words) [view diff] exact match in snippet view article find links to article
family". Hattula K, Peränen J (2000). "FIP-2, a coiled-coil protein, links Huntingtin to Rab8 and modulates cellular morphogenesis". Current Biology. 10 (24):
Aggresome (1,481 words) [view diff] exact match in snippet view article find links to article
ankyrin-like repeat in synphilin 1 with an aggresome-targeting signal from huntingtin was sufficient for aggresome formation upon inhibition of the proteasome
ARFIP2 (673 words) [view diff] exact match in snippet view article find links to article
D'Souza-Schorey C (March 2002). "Arfaptin 2 regulates the aggregation of mutant huntingtin protein". Nature Cell Biology. 4 (3): 240–5. doi:10.1038/ncb761. PMID 11854752
SH3GL1 (887 words) [view diff] exact match in snippet view article find links to article
EEN gene family, new interacting partners for dynamin, synaptojanin and huntingtin proteins". Biochem. J. 348 (2): 447–58. doi:10.1042/0264-6021:3480447
Acetylation (5,191 words) [view diff] exact match in snippet view article find links to article
interaction partners are involved in the N-terminal acetylation by NatA. Huntingtin interacting protein K (HYPK) interacts with hNatA on the ribosome to affect
Molecular tweezers (1,928 words) [view diff] exact match in snippet view article find links to article
other synucleinopathies and is involved in spinal-cord injury; mutant huntingtin, which causes Huntington's disease; islet amyloid polypeptide (amylin)
Actin-binding protein (742 words) [view diff] exact match in snippet view article find links to article
Hrp65-2 Hectochlorin HS1 (actin binding protein) Helicase II Hsp27 HIP1 (Huntingtin Interacting protein 1) Hsp70 Histactophilin Hsp90 Histidine rich protein
EEF1G (1,194 words) [view diff] exact match in snippet view article find links to article
EE (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell. 15 (6): 853–65. doi:10
NAA15 (3,001 words) [view diff] exact match in snippet view article find links to article
scaffold for other factors, including the chaperone like protein HYPK (Huntingtin Interacting Protein K) and Naa50, the catalytic acetyltransferase subunit
DNAJA1 (928 words) [view diff] exact match in snippet view article find links to article
interaction of Hsp40 and Hsp70 family chaperones with truncated N-terminal huntingtin: their role in suppression of aggregation and cellular toxicity". Hum
GTF3A (877 words) [view diff] exact match in snippet view article find links to article
Kumar PD, Mizukami I, Smithson GM, Bradley SV, et al. (November 2001). "Huntingtin interacting protein 1 Is a clathrin coat binding protein required for
DNAJA2 (720 words) [view diff] exact match in snippet view article find links to article
MJ, et al. (2003). "Yeast genes that enhance the toxicity of a mutant huntingtin fragment or alpha-synuclein". Science. 302 (5651): 1769–72. doi:10.1126/science
Transcription elongation regulator 1 (1,194 words) [view diff] exact match in snippet view article find links to article
(2001). "The Gln-Ala repeat transcriptional activator CA150 interacts with huntingtin: neuropathologic and genetic evidence for a role in Huntington's disease
KIAA1377 (612 words) [view diff] exact match in snippet view article find links to article
et al. (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell. 15 (6): 853–65. doi:10
FKBP2 (838 words) [view diff] exact match in snippet view article find links to article
Muchowski PJ (2003). "Yeast genes that enhance the toxicity of a mutant huntingtin fragment or alpha-synuclein". Science. 302 (5651): 1769–72. Bibcode:2003Sci
PACSIN1 (473 words) [view diff] exact match in snippet view article find links to article
Charles V, Tagle DA, Plomann M (Oct 2002). "PACSIN 1 interacts with huntingtin and is absent from synaptic varicosities in presymptomatic Huntington's
DNAJB6 (1,104 words) [view diff] exact match in snippet view article find links to article
"Characterization of a brain-enriched chaperone, MRJ, that inhibits Huntingtin aggregation and toxicity independently". The Journal of Biological Chemistry
SERF2 (345 words) [view diff] exact match in snippet view article find links to article
Barnes GT, Srinidhi J, Chen J, Gusella JF, MacDonald ME (September 1998). "Huntingtin interacts with a family of WW domain proteins". Human Molecular Genetics
PFN2 (1,123 words) [view diff] exact match in snippet view article find links to article
et al. (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell. 15 (6): 853–65. doi:10
Axoplasm (1,231 words) [view diff] exact match in snippet view article find links to article
; Björkblom, B.; Coffey, E.; Bagnato, C.; Han, D. (2009). "Pathogenic huntingtin inhibits fast axonal transport by activating JNK3 and phosphorylating
AP2A2 (1,083 words) [view diff] exact match in snippet view article find links to article
Barnes GT, Srinidhi J, Chen J, Gusella JF, MacDonald ME (Sep 1998). "Huntingtin interacts with a family of WW domain proteins". Human Molecular Genetics
UTP14A (578 words) [view diff] exact match in snippet view article find links to article
et al. (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell. 15 (6): 853–65. doi:10
ING5 (455 words) [view diff] exact match in snippet view article find links to article
et al. (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell. 15 (6): 853–865. doi:10
Transmembrane protein 53 (708 words) [view diff] exact match in snippet view article find links to article
(Jan 2006). "Mutant huntingtin alters MAPK signaling pathways in PC12 and striatal cells: ERK1/2 protects against mutant huntingtin-associated toxicity"
ECH1 (554 words) [view diff] exact match in snippet view article find links to article
et al. (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell. 15 (6): 853–65. doi:10
Praobdellidae (264 words) [view diff] exact match in snippet view article find links to article
0010057&imageURI=info:doi/10.1371/journal.pone.0010057.g002# Kaltenbach LS et al. (2007) Huntingtin Interacting Proteins Are Genetic Modifiers of Neurodegeneration. PLoS
MAGEH1 (490 words) [view diff] exact match in snippet view article find links to article
et al. (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell. 15 (6): 853–65. doi:10
Pridopidine (1,410 words) [view diff] exact match in snippet view article find links to article
(2021). 6.Eddings, C. R. et al. Pridopidine protects neurons from mutant-huntingtin toxicity via the sigma-1 receptor. Neurobiol. Dis. (2019) doi:10.1016/j
Sangamo Therapeutics (783 words) [view diff] exact match in snippet view article find links to article
therapy updates". FierceBiotech. Retrieved July 29, 2020. "Exciting new Huntingtin lowering tool described - HDBuzz - Huntington's disease research news"
LUC7L (498 words) [view diff] exact match in snippet view article find links to article
et al. (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell. 15 (6): 853–65. doi:10
Clinical neurochemistry (2,609 words) [view diff] exact match in snippet view article find links to article
depression and psychosis. The disease is caused by a mutation in the Huntingtin gene, on chromosome 4, which causes abnormally large numbers of glutamate
Genome (6,467 words) [view diff] exact match in snippet view article find links to article
repeats in exons or introns can cause disease. For example, the human gene huntingtin typically contains 6–29 tandem repeats of the nucleotides CAG (encoding
Ligand-dependent nuclear receptor-interacting factor 1 (354 words) [view diff] exact match in snippet view article find links to article
(September 2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Molecular Cell. 15 (6): 853–65
IMMT (947 words) [view diff] exact match in snippet view article find links to article
et al. (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell. 15 (6): 853–65. doi:10
MTSS1 (742 words) [view diff] exact match in snippet view article find links to article
et al. (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell. 15 (6): 853–65. doi:10
PABPC4 (1,218 words) [view diff] exact match in snippet view article find links to article
EE (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell. 15 (6): 853–65. doi:10
HLTF (967 words) [view diff] exact match in snippet view article find links to article
et al. (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell. 15 (6): 853–65. doi:10
PLS3 (797 words) [view diff] exact match in snippet view article find links to article
PMID 15741236. Ralser M, Nonhoff U, Albrecht M, et al. (2005). "Ataxin-2 and huntingtin interact with endophilin-A complexes to function in plastin-associated
Caspase 8 (2,274 words) [view diff] exact match in snippet view article find links to article
Nicholson DW (February 2002). "Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi". Nat. Cell Biol.
RE1-silencing transcription factor (2,007 words) [view diff] exact match in snippet view article find links to article
BR, Hayden MR, Timmusk T, Rigamonti D, Cattaneo E (September 2003). "Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled
TFAP2A (3,046 words) [view diff] exact match in snippet view article find links to article
Mizukami I, Smithson GM, Bradley SV, Parlow AF, Ross TS (Nov 2001). "Huntingtin interacting protein 1 Is a clathrin coat binding protein required for
RE1-silencing transcription factor (2,007 words) [view diff] exact match in snippet view article find links to article
BR, Hayden MR, Timmusk T, Rigamonti D, Cattaneo E (September 2003). "Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled
PCM1 (1,716 words) [view diff] exact match in snippet view article find links to article
PMC 2119948. PMID 8120099. Engelender S, Sharp AH, Colomer V, et al. (1998). "Huntingtin-associated protein 1 (HAP1) interacts with the p150Glued subunit of dynactin"
GIT1 (1,278 words) [view diff] exact match in snippet view article find links to article
EE (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell. 15 (6): 853–865. doi:10
Nader Pourmand (682 words) [view diff] exact match in snippet view article find links to article
Chaves, Gepoliano; Stanley, John; Pourmand, Nader (2019-08-23). "Mutant Huntingtin Affects Diabetes and Alzheimer's Markers in Human and Cell Models of Huntington's
LUC7L2 (560 words) [view diff] exact match in snippet view article find links to article
et al. (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell. 15 (6): 853–65. doi:10
HSF1 (2,411 words) [view diff] exact match in snippet view article find links to article
shock response in cells expressing full-length polyglutamine-expanded huntingtin". PLOS ONE. 7 (5): e37929. Bibcode:2012PLoSO...737929C. doi:10.1371/journal
Clioquinol (1,176 words) [view diff] exact match in snippet view article find links to article
Nguyen T, Hamby A, Massa SM (2005). "Clioquinol down-regulates mutant huntingtin expression in vitro and mitigates pathology in a Huntington's disease
Extrasynaptic NMDA receptor (627 words) [view diff] exact match in snippet view article find links to article
NMDA receptor activity influences inclusions and neurotoxicity of mutant huntingtin". Nature Medicine. 15 (12): 1407–1413. doi:10.1038/nm.2056. ISSN 1546-170X
MAP1LC3A (1,140 words) [view diff] exact match in snippet view article find links to article
et al. (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell. 15 (6): 853–65. doi:10
Cytoskeleton (4,371 words) [view diff] exact match in snippet view article find links to article
PMC 2754410. PMID 19479823. Caviston JP, Holzbaur EL (April 2009). "Huntingtin protein is an essential integrator of intracellular vesicular trafficking"
BRD7 (1,068 words) [view diff] exact match in snippet view article find links to article
et al. (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell. 15 (6): 853–865. doi:10
BECN1 (1,411 words) [view diff] exact match in snippet view article find links to article
et al. (May 2006). "Regulation of intracellular accumulation of mutant Huntingtin by Beclin 1". The Journal of Biological Chemistry. 281 (20): 14474–85
PPHLN1 (623 words) [view diff] exact match in snippet view article find links to article
et al. (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell. 15 (6): 853–65. doi:10
Cystathionine beta synthase (3,179 words) [view diff] exact match in snippet view article find links to article
PMID 10338090. Jones AL (1999). "The localization and interactions of huntingtin". Philos. Trans. R. Soc. Lond. B Biol. Sci. 354 (1386): 1021–7. doi:10
MED31 (757 words) [view diff] exact match in snippet view article find links to article
et al. (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell. 15 (6): 853–865. doi:10
HGS (gene) (1,391 words) [view diff] exact match in snippet view article
1007/BF03402003. PMC 2039936. PMID 11984006. Li Y, Chin LS, Levey AI, Li L (2002). "Huntingtin-associated protein 1 interacts with hepatocyte growth factor-regulated
AKAP8L (1,012 words) [view diff] exact match in snippet view article find links to article
(2006). "Interaction of the nuclear matrix protein NAKAP with HypA and huntingtin: implications for nuclear toxicity in Huntington's disease pathogenesis"
CPLX2 (912 words) [view diff] exact match in snippet view article find links to article
Edwardson JM, Wang CT, Gong B, et al. (2003). "Expression of mutant huntingtin blocks exocytosis in PC12 cells by depletion of complexin II". J. Biol
KAT7 (gene) (1,232 words) [view diff] exact match in snippet view article
(Sep 2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Molecular Cell. 15 (6): 853–65
CRMP1 (1,021 words) [view diff] exact match in snippet view article find links to article
et al. (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell. 15 (6): 853–65. doi:10
SH3GL2 (1,178 words) [view diff] exact match in snippet view article find links to article
EEN gene family, new interacting partners for dynamin, synaptojanin and huntingtin proteins". Biochem. J. 348 (2): 447–58. doi:10.1042/0264-6021:3480447
MDH1 (770 words) [view diff] exact match in snippet view article find links to article
Kurschner C, Ellerby LM, Peltier JM, Botas J, Hughes RE (May 2007). "Huntingtin interacting proteins are genetic modifiers of neurodegeneration". PLOS
SYMPK (1,220 words) [view diff] exact match in snippet view article find links to article
Barnes GT, Srinidhi J, Chen J, Gusella JF, MacDonald ME (Sep 1998). "Huntingtin interacts with a family of WW domain proteins". Human Molecular Genetics
Nuclear receptor co-repressor 1 (2,677 words) [view diff] exact match in snippet view article find links to article
transcriptional repressor proteins with the Huntington's disease gene product, huntingtin". Hum. Mol. Genet. 8 (9): 1647–55. doi:10.1093/hmg/8.9.1647. PMID 10441327
ZHX1 (874 words) [view diff] exact match in snippet view article find links to article
(September 2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Molecular Cell. 15 (6): 853–65
FEZ1 (1,052 words) [view diff] exact match in snippet view article find links to article
et al. (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell. 15 (6): 853–65. doi:10
SYVN1 (1,065 words) [view diff] exact match in snippet view article find links to article
the degradation and suppresses the toxicity of polyglutamine-expanded huntingtin". Experimental Cell Research. 313 (3): 538–50. doi:10.1016/j.yexcr.2006
Tropomyosin receptor kinase A (3,264 words) [view diff] exact match in snippet view article find links to article
YF (February 2002). "Expression of full-length polyglutamine-expanded Huntingtin disrupts growth factor receptor signaling in rat pheochromocytoma (PC12)
Caudate nucleus (4,490 words) [view diff] exact match in snippet view article find links to article
(September 2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Molecular Cell. 15 (6): 853–65
TADA3L (1,257 words) [view diff] exact match in snippet view article find links to article
(Sep 2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Molecular Cell. 15 (6): 853–65
SIN3A (3,125 words) [view diff] exact match in snippet view article find links to article
transcriptional repressor proteins with the Huntington's disease gene product, huntingtin". Human Molecular Genetics. 8 (9): 1647–55. doi:10.1093/hmg/8.9.1647.
Frameshift mutation (4,411 words) [view diff] exact match in snippet view article find links to article
deletion or single nucleotide insertion within the polyglutamine tract of huntingtin exon 1 would shift the CAG, polyglutamineen coding frame by +1 (+1 frame
SAP30 (1,833 words) [view diff] exact match in snippet view article find links to article
transcriptional repressor proteins with the Huntington's disease gene product, huntingtin". Human Molecular Genetics. 8 (9): 1647–55. doi:10.1093/hmg/8.9.1647.
Hilmar Bading (1,094 words) [view diff] exact match in snippet view article find links to article
NMDA receptor activity influences inclusions and neurotoxicity of mutant huntingtin". Nature Medicine. 15 (12): 1407–1413. doi:10.1038/nm.2056. ISSN 1546-170X
Binding immunoglobulin protein (3,624 words) [view diff] exact match in snippet view article find links to article
which promote ATP hydrolysis. BiP is also a validated substrate of HYPE (Huntingtin Yeast Interacting Partner E), which can adenylate BiP at multiple residues
Anne Bertolotti (1,272 words) [view diff] exact match in snippet view article find links to article
Bertolotti, Anne (2006-11-24). "Critical role of the proline-rich region in Huntingtin for aggregation and cytotoxicity in yeast". The Journal of Biological
Phillip D. Zamore (1,077 words) [view diff] exact match in snippet view article find links to article
; Zamore, P. D.; Aronin, N. (2007). "Therapeutic silencing of mutant huntingtin with siRNA attenuates striatal and cortical neuropathology and behavioral
Rohit Pappu (866 words) [view diff] exact match in snippet view article find links to article
"Unmasking the roles of N- and C-terminal flanking sequences from exon 1 of huntingtin as modulators of polyglutamine aggregation". Proceedings of the National
SETDB1 (2,001 words) [view diff] exact match in snippet view article find links to article
EE (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell. 15 (6): 853–65. doi:10
Growth differentiation factor-9 (3,318 words) [view diff] exact match in snippet view article find links to article
et al. (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell. 15 (6): 853–65. doi:10
N-alpha-acetyltransferase 10 (5,349 words) [view diff] exact match in snippet view article find links to article
Ronen (10 May 2018). "Structure of Human NatA and Its Regulation by the Huntingtin Interacting Protein HYPK". Structure. 26 (7): 925–935.e8. doi:10.1016/j
Erika Holzbaur (795 words) [view diff] exact match in snippet view article find links to article
Worley, Paul; Holzbaur, Erika L.F.; Ross, Christopher A. (1997-12-01). "Huntingtin-associated Protein 1 (HAP1) Interacts with the p150Glued Bubunit of Dynactin"
GADD45G (3,092 words) [view diff] exact match in snippet view article find links to article
EE (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell. 15 (6): 853–65. doi:10
Proteopathy (4,529 words) [view diff] exact match in snippet view article find links to article
"Single-stranded RNAs use RNAi to potently and allele-selectively inhibit mutant huntingtin expression". Cell. 150 (5): 895–908. doi:10.1016/j.cell.2012.08.002. PMC 3444165
DSCR1 (1,991 words) [view diff] exact match in snippet view article find links to article
(RCAN1-1L) is deficient in Huntington disease and protective against mutant huntingtin toxicity in vitro". The Journal of Biological Chemistry. 284 (18): 11845–53
Weighted correlation network analysis (3,082 words) [view diff] exact match in snippet view article find links to article
Horvath S, Loo JA, Yang XW (12 July 2012). "Network organization of the huntingtin proteomic interactome in mammalian brain". Neuron. 75 (1): 41–57. doi:10
G-quadruplex (11,497 words) [view diff] exact match in snippet view article find links to article
in the Huntington disease gene / allele-specific silencing of mutant huntingtin". Molecular Therapy. 19 (12): 2178–85. doi:10.1038/mt.2011.201. PMC 3242664
DNM1L (2,553 words) [view diff] exact match in snippet view article find links to article
(September 2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Molecular Cell. 15 (6): 853–65
MTOR (12,966 words) [view diff] exact match in snippet view article find links to article
demonstrate that treatment with rapamycin facilitates the clearance of huntingtin aggregates. Perhaps the same treatment may be useful in clearing Aβ deposits
CRISPR gene editing (11,269 words) [view diff] exact match in snippet view article find links to article
WJ, Olejniczak M (2018). "Precise Excision of the CAG Tract from the Huntingtin Gene by Cas9 Nickases". Frontiers in Neuroscience. 12: 75. doi:10.3389/fnins
Alpha-synuclein (8,460 words) [view diff] exact match in snippet view article find links to article
PJ (December 2003). "Yeast genes that enhance the toxicity of a mutant huntingtin fragment or alpha-synuclein". Science. 302 (5651): 1769–72. Bibcode:2003Sci
XMAP215-Dis1 family (2,170 words) [view diff] exact match in snippet view article find links to article
members of the XMAP215/Dis1 family. Each domain consists of six HEAT (Huntingtin, Elongation factor 3, the PR65/A subunit of protein phosphatase 2A and
BNIP3 (2,667 words) [view diff] exact match in snippet view article find links to article
Marchi P, Ascardi C, Alberti L, Di Pardo A, et al. (January 2010). "Mutant Huntingtin induces activation of the Bcl-2/adenovirus E1B 19-kDa interacting protein
Jean-Louis Mandel (1,973 words) [view diff] exact match in snippet view article find links to article
Lunkes, A, […], Mandel, J.-L. and Trottier Y. Proteases acting on mutant Huntingtin generate cleaved products that differentially build up cytoplasmic and
Stress granule (12,979 words) [view diff] exact match in snippet view article find links to article
Chighladze E, Arbez N, Boronina T, Herbrich S, Cole RN, Ross CA (May 2012). "Huntingtin protein interactions altered by polyglutamine expansion as determined
Infrared Nanospectroscopy (AFM-IR) (7,790 words) [view diff] exact match in snippet view article
the behaviour of disease-related proteins and peptides, such as Aβ42, huntingtin and FUS, which are involved in the onset of Alzheimer's, Huntington's
Outline of the human brain (8,442 words) [view diff] exact match in snippet view article find links to article
globally by 2050. Huntington's disease – caused by a mutation in the huntingtin gene (HTT) causing and array of symptoms including abnormal involuntary
Ravi Allada (4,429 words) [view diff] exact match in snippet view article find links to article
Function in Concert with Heat Shock Organizing Protein to Modulate Mutant Huntingtin Aggregation and Toxicity". Cell Reports. 27 (1): 59–70.e4. doi:10.1016/j