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Combinatorial Chemistry & High Throughput Screening
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Combinatorial Chemistry & High Throughput Screening is a peer-reviewed scientific journal that covers combinatorial chemistry. It was established in 1998Allophycocyanin (427 words) [view diff] case mismatch in snippet view article find links to article
abbreviated APC. To be effectively used in applications such as FACS, High-Throughput Screening (HTS) and microscopy, APC needs to be chemically cross-linkedVaccine trial (1,189 words) [view diff] no match in snippet view article find links to article
identified through preclinical evaluations that could involve high throughput screening and selecting the proper antigen to invoke an immune responsePZM21 (440 words) [view diff] exact match in snippet view article find links to article
research was described as a compelling example of how modern high-throughput screening techniques can be used to discover new chemotypes with specificCeramidase (328 words) [view diff] exact match in snippet view article find links to article
reported to date. Inhibitors of nCDase were identified via a high-throughput screening effort of large chemical libraries at Scripps Research. MultipleVerenium Corporation (377 words) [view diff] exact match in snippet view article find links to article
collection of microbial genes, numbering in the billions, using high-throughput screening technologies designed to identify unique enzymes as product candidatesSLAS Discovery (301 words) [view diff] exact match in snippet view article find links to article
biomarker discovery; assay development; virtual, medium- or high-throughput screening; lead generation/optimization; chemical biology; and informaticsHomologous somatic pairing (809 words) [view diff] no match in snippet view article find links to article
Somatic pairing of homologous chromosomes is similar to pre- and early meiotic pairing (see article: Homologous chromosome#In meiosis), and has been observedBacMam (1,675 words) [view diff] no match in snippet view article find links to article
Baculovirus gene transfer into Mammalian cells (BacMam) is the use of a baculovirus to deliver genes to mammalian cells. Baculoviruses are insect virusesGerry Wright (450 words) [view diff] no match in snippet view article find links to article
Antimicrobial Research Centre, and co-founder of the McMaster High Throughput Screening Facility. Wright obtained his BSc in Biochemistry and his PhDBioinstructive material (819 words) [view diff] no match in snippet view article find links to article
general recognition of the important role of adsorbed biomolecules, high throughput screening of large libraries of materials, topographies, and shapes areList of Dove Medical Press academic journals (679 words) [view diff] no match in snippet view article find links to article
International Journal of General Medicine International Journal of High Throughput Screening† International Journal of Interferon, Cytokine and Mediator Research†Anoikis (640 words) [view diff] exact match in snippet view article find links to article
ἀν- "without", οἰκ- "house", and the suffix -ις. Using a novel high-throughput screening assay, Mawji et al. showed that anisomycin can sensitize metastaticUlrich Schwaneberg (839 words) [view diff] exact match in snippet view article find links to article
(e.g. PLICing, SeSaM, OmniChange, cepPCR, PePevo), as well as high-throughput screening systems (e.g. Fur-Shell). His work group has elucidated generalC+-probability (476 words) [view diff] case mismatch in snippet view article find links to article
2217/14622416.10.3.345. PMID 20397965. Zhang XHD (2011). Optimal High-Throughput Screening: Practical Experimental Design and Data Analysis for Genome-scaleWilliam Kisaalita (390 words) [view diff] no match in snippet view article find links to article
following: Tissue engineering Cell-surface interactions Assays for high throughput screening (HTS) Renewable energy utilization with emphasis on biogas-poweredReagent (752 words) [view diff] exact match in snippet view article find links to article
Walters, MA (July 2014). "The essential roles of chemistry in high-throughput screening triage". Future Medicinal Chemistry. 6 (11): 1265–1290. doi:10Life Sciences Institute (945 words) [view diff] exact match in snippet view article find links to article
the institute's first two research cores opened, supporting high-throughput screening and structural biology research : the Center for Structural BiologyViability assay (1,372 words) [view diff] case mismatch in snippet view article find links to article
(2013-03-04). "High-Throughput Screening Assays for the Assessment of Cytotoxicity". In Steinberg P (ed.). High-Throughput Screening Methods in ToxicityAnton Windfelder (1,622 words) [view diff] exact match in snippet view article find links to article
Trenczek. Windfelder received his doctorate in 2021 on the topic "High-throughput screening of insect larvae as a replacement for mammalian models of gutSMILES arbitrary target specification (1,749 words) [view diff] exact match in snippet view article find links to article
compounds when performing strategic pooling of compounds for high-throughput screening. The REOS (rapid elimination of swill) procedure uses SMARTS toCytotoxicity (1,379 words) [view diff] exact match in snippet view article find links to article
PMID 17512890. Fan F, Wood KV (February 2007). "Bioluminescent assays for high-throughput screening". Assay Drug Dev Technol. 5 (1): 127–36. doi:10.1089/adt.2006Reverse transfection (919 words) [view diff] exact match in snippet view article find links to article
transfection efficiency. Labour-saving materials (less DNA is required) High-throughput screening; hundreds of genes may be expressed in cells on a single microarrayGel doc (992 words) [view diff] no match in snippet view article find links to article
systems are broadly used to detect wide range of analytes with high- throughput screening due to its sensitivity, efficiency, low noise. Verifying the loadingChiral column chromatography (2,371 words) [view diff] exact match in snippet view article find links to article
a chiral method development laboratory settings, acts like a high-throughput screening protocol, of conducting a systematic screening of various CSP'sTransphosphorylation (327 words) [view diff] no match in snippet view article find links to article
murine intestinal alkaline phosphatase (ML260) by concurrent ultra-high throughput screening against human and mouse isozymes". Bioorganic & Medicinal ChemistryGinkgo Bioworks (1,464 words) [view diff] exact match in snippet view article find links to article
AG, a leading bioengineering company and its proprietary ultra-high-throughput screening platform.[self-published source] On 6 June 2022, it was reportedToxicogenomics (1,419 words) [view diff] exact match in snippet view article find links to article
concentration-response assessment of chemicals: the 1000 genomes high-throughput screening study". Environmental Health Perspectives. 123 (5): 458–66. doi:10Todd Golub (394 words) [view diff] exact match in snippet view article find links to article
SA, O'Malley S, Stockwell BR, Golub TR. Gene expression-based high-throughput screening (GE-HTS) and application to leukemia differentiation. Nat GenetDesorption electrospray ionization (3,121 words) [view diff] no match in snippet view article find links to article
reverse-phase HPLC can be combined with this procedure to produce high throughput screening of natural products as well. The incorporation of the electrochemistryPhycobiliprotein (538 words) [view diff] exact match in snippet view article find links to article
It is commonly used in immunoassays such as flow cytometry and high-throughput screening. It is also a common acceptor dye for FRET assays. StructuralAntiprion drug (240 words) [view diff] case mismatch in snippet view article find links to article
(26 May 2005). "Systematic Identification of Antiprion Drugs by High-Throughput Screening Based on Scanning for Intensely Fluorescent Targets". JournalMicrophysiometry (389 words) [view diff] no match in snippet view article find links to article
"High-performance microphysiometry in drug discovery", Devlin JP (ed) High Throughput Screening: The Discovery of Bioactive Substances. Marcel Dekker, New YorkPhytochemistry (1,243 words) [view diff] exact match in snippet view article find links to article
Walters MA (July 2014). "The essential roles of chemistry in high-throughput screening triage". Future Medicinal Chemistry. 6 (11): 1265–90. doi:10.4155/fmcSM-130686 (333 words) [view diff] no match in snippet view article find links to article
growth hormone secretagogue, SM-130686". Combinatorial Chemistry & High Throughput Screening. 9 (3): 187–96. doi:10.2174/138620706776055548. PMID 16533152Automated synthesis (2,989 words) [view diff] case mismatch in snippet view article find links to article
(January 2003). "Combinatorial Methods, Automated Synthesis and High-Throughput Screening in Polymer Research: Past and Present". Macromolecular Rapid CommunicationsMethods to investigate protein–protein interactions (4,515 words) [view diff] exact match in snippet view article find links to article
identified by the presence of the label. Phage display is used for the high-throughput screening of protein interactions. In-vivo crosslinking of protein complexesParallel artificial membrane permeability assay (615 words) [view diff] no match in snippet view article find links to article
Aug. Kansy M, Senner F, Gubernator K. (1998) Physicochemical high throughput screening: parallel artificial membrane permeability assay in the descriptionNational Toxicology Program (578 words) [view diff] exact match in snippet view article find links to article
NTP. Official website NICEATM website Tox21 – U.S. Government high-throughput screening initiative Ninth World Congress on Alternatives and Animal UseUgi reaction (1,497 words) [view diff] no match in snippet view article find links to article
natural and preparative chemistry". Combinatorial Chemistry & High Throughput Screening. 4 (1): 1–34. doi:10.2174/1386207013331291. PMID 11281825. BienaymeSurfactin (1,302 words) [view diff] no match in snippet view article find links to article
relationships to design new bioactive agents". Combinatorial Chemistry & High Throughput Screening. 6 (6): 541–56. doi:10.2174/138620703106298716. PMID 14529379Manduca sexta (2,957 words) [view diff] exact match in snippet view article find links to article
Gabriele A.; Vilcinskas, Andreas; Grimm, Jan (November 24, 2022). "High-throughput screening of caterpillars as a platform to study host–microbe interactionsTLX (936 words) [view diff] exact match in snippet view article find links to article
dydrogesterone), have been discovered in high-throughput screening that enhance TLX's ability of transcription repression with highMucoromycota (1,600 words) [view diff] exact match in snippet view article find links to article
Ekeberg D, Afseth NK, Mounier J, Shapaval V (December 2018). "High-throughput screening of Mucoromycota fungi for production of low- and high-value lipids"1-Deoxynojirimycin (682 words) [view diff] case mismatch in snippet view article find links to article
Shuang-Yan (2015-02-24). "Design and Application of a Novel High-throughput Screening Technique for 1-Deoxynojirimycin". Scientific Reports. 5 (1):Ipamorelin (478 words) [view diff] no match in snippet view article find links to article
2006). "Growth hormone secretagogues". Combinatorial Chemistry & High Throughput Screening. 9 (3): 175–80. doi:10.2174/138620706776055458. PMID 16533150Mannosylglycerate synthase (191 words) [view diff] exact match in snippet view article find links to article
Gilbert HJ, Davies GJ (July 2005). "Structural dissection and high-throughput screening of mannosylglycerate synthase". Nature Structural & MolecularMIMETAS (499 words) [view diff] exact match in snippet view article find links to article
plate format. This renders the technology suitable for low- to high-throughput screening applications. Mimetas develops a range of tissue- and diseaseGlycomics (1,861 words) [view diff] exact match in snippet view article find links to article
spectrometry in glycan analysis Lectin and antibody arrays provide high-throughput screening of many samples containing glycans. This method uses either naturallyZebraBox (360 words) [view diff] case mismatch in snippet view article find links to article
"Zebrafish Behavioral Assays in Toxicology". In Zhu H, Xia M (eds.). High-Throughput Screening Assays in Toxicology. Methods in Molecular Biology. Vol. 2474Gonadotropin-releasing hormone receptor (1,054 words) [view diff] no match in snippet view article find links to article
Chase P, Scampavia L, Janovick JA (May 2014). "A Phenotypic High Throughput Screening Assay for the Identification of Pharmacoperones for the GonadotropinMatrix-assisted laser desorption electrospray ionization (4,003 words) [view diff] exact match in snippet view article find links to article
tube ion mobility spectrometer-mass spectrometer (IMS-MS) for high-throughput screening. These integrations provide more reliable raw data for MSI asPesticide research (1,397 words) [view diff] exact match in snippet view article find links to article
primary hit rate of 10.9%, much higher than for conventional high-throughput screening. Other tools like three-dimensional (3D) shape, atom-type similarityChlorophyllin (905 words) [view diff] no match in snippet view article find links to article
c Mediated Pathway in Mice Model". Combinatorial Chemistry & High Throughput Screening. 24 (10): 1618–1627. doi:10.2174/1386207323666201230093510. PMID 33380297Lanosterol 14 alpha-demethylase (1,066 words) [view diff] exact match in snippet view article find links to article
"Small-molecule scaffolds for CYP51 inhibitors identified by high-throughput screening and defined by X-ray crystallography". Antimicrobial Agents andChemical compound microarray (463 words) [view diff] no match in snippet view article find links to article
8721–8726 [7]. Ma, H. et al. (2005) "Nanoliter Homogenous Ultra High Throughput Screening Microarray for Lead Discoveries and IC50 Profiling". Assay DrugCytopathic effect (1,407 words) [view diff] case mismatch in snippet view article find links to article
Tianyi (2012). "Development of a Robust Cytopathic Effect-Based High-Throughput Screening Assay to Identify Novel Inhibitors of Dengue Virus". AntimicrobialSalinomycin (822 words) [view diff] exact match in snippet view article find links to article
"Identification of selective inhibitors of cancer stem cells by high-throughput screening". Cell. 138 (4): 645–59. doi:10.1016/j.cell.2009.06.034. PMC 4892125Materiomics (705 words) [view diff] case mismatch in snippet view article find links to article
pp. 153–161, 2011, doi:10.1007/s12668-011-0022-5 Materiomics: High-Throughput Screening of Biomaterial Properties [7] Biomateriomics [8] Master of Materiomics:In vitro (3,138 words) [view diff] exact match in snippet view article find links to article
In vitro methods can be miniaturized and automated, yielding high-throughput screening methods for testing molecules in pharmacology or toxicology. TheCALUX (591 words) [view diff] exact match in snippet view article find links to article
disease, the AhR-CALUX bioassay is also being used widely as a high-throughput screening method to identify and characterize AhR-active chemicals as potentialBatch effect (925 words) [view diff] exact match in snippet view article find links to article
Berger, Bonnie (ed.). "BatchI: Batch effect Identification in high-throughput screening data using a dynamic programming algorithm". Bioinformatics. 35Brahm Shanker Srivastava (1,101 words) [view diff] no match in snippet view article find links to article
Mycobacterium aurum expressing firefly luciferase for rapid and high throughput screening of antimycobacterial drugs in vitro and in infected macrophages"Automated patch clamp (2,412 words) [view diff] no match in snippet view article find links to article
Large CH (2009). "Automated Patch Clamping Using the QPatch". High Throughput Screening. Methods in Molecular Biology. Vol. 565. pp. 209–23. doi:10Methylation specific oligonucleotide microarray (690 words) [view diff] no match in snippet view article find links to article
Finkelstein S, Ren B, Kokkinakis D, et al. (February 2005). "High throughput screening of methylation status of genes in prostate cancer using an oligonucleotideHigh production volume chemicals (1,772 words) [view diff] exact match in snippet view article find links to article
which uses "automated chemical screening technologies (called "high-throughput screening assays") to expose living cells or isolated proteins to chemicals"Vicriviroc (2,046 words) [view diff] exact match in snippet view article find links to article
first-generation compounds like SCH-C. Vicriviroc was discovered in high-throughput screening and structure-activity relationships (SAR) analysis. When comparedPregnane X receptor (1,978 words) [view diff] case mismatch in snippet view article find links to article
Lin W, Goktug AN, Wu J, Currier DG, Chen T (December 2017). "High-Throughput Screening Identifies 1,4,5-Substituted 1,2,3-Triazole Analogs as PotentZoliflodacin (643 words) [view diff] no match in snippet view article find links to article
separate bacterial DNA, thereby inhibiting cell replication. A high throughput screening campaign aimed at identifying compounds with whole cell antibacterial2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (596 words) [view diff] exact match in snippet view article find links to article
enzymes as antiinfective drug targets: substrate synthesis and high-throughput screening methods". J. Org. Chem. 71 (23): 8824–34. doi:10.1021/jo061466oPyridoxal phosphate (2,937 words) [view diff] exact match in snippet view article find links to article
). "New classes of alanine racemase inhibitors identified by high-throughput screening show antimicrobial activity against Mycobacterium tuberculosis"CCDC22 (657 words) [view diff] no match in snippet view article find links to article
"Systematically generated antibodies against human gene products: high throughput screening on sections from the rat nervous system". Neuroscience. 146 (4):Tom Baruch (1,268 words) [view diff] no match in snippet view article find links to article
genomics, Moore’s law hardware and custom software to enable high throughput screening of new materials. Tom has pioneered CMEA’s investments in companiesPost-metallocene catalyst (958 words) [view diff] no match in snippet view article find links to article
cyclopentadienyl derivatives, but great diversity was uncovered through high throughput screening. These post-metallocene catalysts employ a range of chelatingBenzatropine (1,439 words) [view diff] no match in snippet view article find links to article
Parkinson's disease. Benzatropine has been also identified, by a high throughput screening approach, as a potent differentiating agent for oligodendrocytesSphingosine-1-phosphate receptor (1,266 words) [view diff] exact match in snippet view article find links to article
Rosen H, Mandala S (December 2004). "A rational utilization of high-throughput screening affords selective, orally bioavailable 1-benzyl-3-carboxyazetidineCambridge Biomedical Campus (1,822 words) [view diff] no match in snippet view article find links to article
groups, including antibody engineering, medicinal chemistry and high throughput screening. The University of Cambridge Medical School, established in 1976Susan Lindquist (2,779 words) [view diff] exact match in snippet view article find links to article
neurodegenerative diseases and to test therapeutic strategies through high-throughput screening. Tardiff DF, Jui NT, Khurana V, Tambe MA, Thompson ML, Chung CYLuciferase (2,896 words) [view diff] exact match in snippet view article find links to article
PMID 3407940. Fan F, Wood KV (Feb 2007). "Bioluminescent assays for high-throughput screening". ASSAY and Drug Development Technologies. 5 (1): 127–36. doi:10Aspergillus vadensis (664 words) [view diff] no match in snippet view article find links to article
development of a miniaturized culture method and an automated high‐throughput screening". Letters in Applied Microbiology. 49 (2): 278–282. doi:10.1111/jTILLING (molecular biology) (1,335 words) [view diff] exact match in snippet view article
MN; Yeung, AT; McCallum, CM; Comai, L; Henikoff, S (Jun 2001). "High-throughput screening for induced point mutations". Plant Physiol. 126 (2): 480–4. doi:10Jakub Paś (1,677 words) [view diff] no match in snippet view article find links to article
"In silico prediction of SARS protease inhibitors by virtual high throughput screening". Chemical Biology & Drug Design. 69 (4): 269–79. doi:10.1111/jGlycan (3,161 words) [view diff] exact match in snippet view article find links to article
spectrometry in glycan analysis Lectin and antibody arrays provide high-throughput screening of many samples containing glycans. This method uses either naturallyFANCM (1,914 words) [view diff] case mismatch in snippet view article find links to article
PMID 31138795. Voter AF, Manthei KA, Keck JL (July 2016). "A High-Throughput Screening Strategy to Identify Protein-Protein Interaction Inhibitors ThatJohan Neyts (812 words) [view diff] no match in snippet view article find links to article
guidance of Dr. Pieter Leyssen, a unique lab-in-a-box that allows high throughput screening in a high biosafety environment was designed and built. TogetherErnst Lengyel (771 words) [view diff] exact match in snippet view article find links to article
published in Nature Communications, was the first to describe a high-throughput screening drug-discovery platform for ovarian cancer that mimics the structuralCardiac fibrosis (2,829 words) [view diff] exact match in snippet view article find links to article
5-HT2B agonist, based on the results of theoretical modeling and high-throughput screening. Pergolide was an antiparkinson medications that was in decreasingMALDI imaging (2,217 words) [view diff] no match in snippet view article find links to article
up to today: the state of the art". Combinatorial Chemistry & High Throughput Screening. 12 (2): 156–174. doi:10.2174/138620709787315454. PMID 19199884Amy Rowat (768 words) [view diff] no match in snippet view article find links to article
Ruprecht; Karlan, Beth (2019). "A scalable filtration method for high throughput screening based on cell deformability". Lab on a Chip. 19 (2): 343–357.Protein production (2,654 words) [view diff] no match in snippet view article find links to article
fluorescens is a metabolically versatile organism, allowing for high throughput screening and rapid development of complex proteins. P. fluorescens is mostAssociation of Biomolecular Resource Facilities (1,893 words) [view diff] no match in snippet view article find links to article
technologies that are implemented in core facility settings: Automation: high throughput screening, LIMS, robotics. Protein/Peptide Chemistry: amino acid analysisSeSaM-Biotech GmbH (882 words) [view diff] exact match in snippet view article find links to article
mutagenesis methods in combination with developing and applying high-throughput screening assays for the realization of extensive protein engineering projectsImidazoleglycerol-phosphate dehydratase (535 words) [view diff] exact match in snippet view article find links to article
ISSN 0022-2836. PMID 6990004. Cagney, G.; Uetz, P.; Fields, S. (2000). "High-throughput screening for protein-protein interactions using two-hybrid assay". ApplicationsSodium/iodide cotransporter (3,135 words) [view diff] case mismatch in snippet view article find links to article
AS, Buckalew AR, Simmons SO, Laws SC, Stoker TE (May 2018). "High-Throughput Screening and Quantitative Chemical Ranking for Sodium-Iodide SymporterSouthern Research (1,762 words) [view diff] no match in snippet view article find links to article
disease, and neuroscience. Their current service areas include: High Throughput Screening (HTS), Chemistry, Oncology, Infectious Disease, Neuroscience,Microreactor (2,746 words) [view diff] exact match in snippet view article find links to article
readily be extended to other enzyme-based systems, for example, high-throughput screening of new enzymes and to precision measurements of new processesNoctiluca scintillans (3,598 words) [view diff] case mismatch in snippet view article find links to article
Imaging in Temporal Reaction of G Protein-Coupled Receptor for High-Throughput Screening and Analysis", Bioluminescence, Methods in Molecular Biology,Channel blocker (3,020 words) [view diff] exact match in snippet view article find links to article
(December 2002). "Thiazolidinone CFTR inhibitor identified by high-throughput screening blocks cholera toxin-induced intestinal fluid secretion". TheAkane Kawamura (467 words) [view diff] case mismatch in snippet view article find links to article
Li; Masaaki Sakurai; et al. (23 November 2010). "Quantitative High-Throughput Screening Identifies 8-Hydroxyquinolines as Cell-Active Histone DemethylaseMicroplate (2,565 words) [view diff] exact match in snippet view article find links to article
ISSN 1473-0197. PMC 5996734. PMID 29781496. Inglin, Raffael C. (2015). "High-throughput screening assays for antibacterial and antifungal activities of LactobacillusAssay (3,326 words) [view diff] no match in snippet view article find links to article
automated platform in 96-, 384- or 1536-well microplate formats (High Throughput Screening). Such assays are able to test large number of compounds or analytesDirect analysis in real time (2,883 words) [view diff] exact match in snippet view article find links to article
Hu-Wei (2013-05-07). "Applications of ambient mass spectrometry in high-throughput screening". The Analyst. 138 (11): 3097–103. Bibcode:2013Ana...138.3097LPolyethylenimine (2,400 words) [view diff] no match in snippet view article find links to article
Chemistry. 14 (3): 581–587. doi:10.1021/bc0200529. PMID 12757382. "High Throughput Screening « Polyplus Transfection". Archived from the original on 2010-03-02Moxifloxacin (3,378 words) [view diff] exact match in snippet view article find links to article
"Identification of new drug candidates against Borrelia burgdorferi using high-throughput screening". Drug Design, Development and Therapy. 10: 1307–1322. doi:10Arenavirus (4,051 words) [view diff] no match in snippet view article find links to article
regions where these infections are occurring. For this reason high throughput screening (HTS) of small molecular libraries could be the answer to findingMulti-label classification (2,945 words) [view diff] exact match in snippet view article find links to article
Vladimir B. (2016-11-10). "DRABAL: novel method to mine large high-throughput screening assays using Bayesian active learning". Journal of CheminformaticsWound healing assay (1,516 words) [view diff] no match in snippet view article find links to article
various numbered well-plates options (96 or 384) and allows for high throughput screening, which is a major advantage for various medical research studiesDoug Hilton (1,283 words) [view diff] exact match in snippet view article find links to article
investigative innovations including structural biology, chemistry, high-throughput screening, and mathematics and computational science. expanding the translationalBen Feringa (3,610 words) [view diff] no match in snippet view article find links to article
services in the area of organic synthesis but later developed high throughput screening methods. Staff (20 December 2016). "The Nobel Prize in ChemistryPseudogymnoascus destructans (2,112 words) [view diff] exact match in snippet view article find links to article
GJ; Shtutman M; Chaturvedi V (2011). "Anti fungal testing and high-throughput screening of compound library against Geomyces destructans, the etiologicJames C. Stevens (1,369 words) [view diff] exact match in snippet view article find links to article
first to recognize the potential of combinatorial chemistry and high-throughput screening in the discovery of olefin polymerization catalysts. Stevens’Lactobacillus (4,171 words) [view diff] exact match in snippet view article find links to article
Inglin RC, Stevens MJ, Meile L, Lacroix C, Meile L (July 2015). "High-throughput screening assays for antibacterial and antifungal activities of LactobacillusStandardized mean of a contrast variable (1,733 words) [view diff] case mismatch in snippet view article find links to article
{n}}\lambda \right).} Dual-flashlight plot Zhang XHD (2011). Optimal High-Throughput Screening: Practical Experimental Design and Data Analysis for Genome-scaleScoring functions for docking (2,547 words) [view diff] exact match in snippet view article find links to article
PMID 17554857. Seifert MH, Kraus J, Kramer B (May 2007). "Virtual high-throughput screening of molecular databases". Current Opinion in Drug Discovery & DevelopmentComputer Atlas of Surface Topography of Proteins (1,472 words) [view diff] exact match in snippet view article find links to article
industry, the current priority strategy for target assessment is high-throughput screening (HTS). NMR screenings are applied against large compound datasetsGuangxitoxin (1,770 words) [view diff] no match in snippet view article find links to article
(November 2009). "A KV2.1 gating modifier binding assay suitable for high throughput screening". Channels. 3 (6): 437–47. doi:10.4161/chan.3.6.10201. PMID 21150283Calotropis gigantea (2,361 words) [view diff] no match in snippet view article find links to article
Novel Inhibitor of Sperm Maturation". Combinatorial Chemistry & High Throughput Screening. 20 (1): 82–92. doi:10.2174/1386207320666170116120104. PMID 28093975Roger Y. Tsien (3,942 words) [view diff] no match in snippet view article find links to article
States National Academy of Sciences (1998) Award for Innovation in High Throughput Screening, Society for Biomolecular Screening (1998) Pearse Prize, RoyalInduced pluripotent stem cell (10,512 words) [view diff] exact match in snippet view article find links to article
Haodi; Holmström, Alexandra; Matsa, Elena (15 February 2017). "High-throughput screening of tyrosine kinase inhibitor cardiotoxicity with human inducedGlycome (1,501 words) [view diff] exact match in snippet view article find links to article
spectrometry in glycan analysis Lectin and antibody arrays provide high-throughput screening of many samples containing glycans. This method uses either naturallyChristoph Merten (739 words) [view diff] case mismatch in snippet view article find links to article
Christoph A. (2017). "Single-Virus Droplet Microfluidics for High-Throughput Screening of Neutralizing Epitopes on HIV Particles". Cell Chemical BiologyDrug permeability (519 words) [view diff] no match in snippet view article find links to article
M.; Senner, F.; Gubernator, K. (1998-03-26). "Physicochemical high throughput screening: parallel artificial membrane permeation assay in the descriptionLaser diode thermal desorption (1,995 words) [view diff] case mismatch in snippet view article find links to article
ISSN 1757-6199. PMID 22720651. "News | Changing the Game in High-Throughput Screening". Phytronix. 2018-08-01. Retrieved 2020-07-30. Dion‐Fortier, Annick;Isogenic human disease models (2,046 words) [view diff] exact match in snippet view article find links to article
Kinzler KW (October 2001). "Use of isogenic human cancer cells for high-throughput screening and drug discovery". Nat. Biotechnol. 19 (10): 940–5. doi:10.1038/nbt1001-940Lysozyme PEGylation (1,418 words) [view diff] no match in snippet view article find links to article
(2014). "Optimization of random PEGylation reactions by means of high throughput screening". Biotechnology and Bioengineering. 111 (1): 104–114. doi:10.1002/bitThe Soufflet Group (1,105 words) [view diff] exact match in snippet view article find links to article
OSIRIS: Development of droplet-based microfluidic platform for the high-throughput screening of industrial micro-organisms". www.lbc.espci.fr. Retrieved 2024-02-24Phage display (4,630 words) [view diff] exact match in snippet view article find links to article
libraries. Like the two-hybrid system, phage display is used for the high-throughput screening of protein interactions. In the case of M13 filamentous phageS. Joshua Swamidass (1,329 words) [view diff] no match in snippet view article find links to article
"Influence relevance voting: an accurate and interpretable virtual high throughput screening method". Journal of Chemical Information and Modeling. 49 (4):Bacterial one-hybrid system (1,925 words) [view diff] no match in snippet view article find links to article
Interrogating Zinc Fingure_DNA Interactions". Combinatorial Chemistry & High Throughput Screening. 9 (2006): 301–311. doi:10.2174/138620706776843147. PMID 16724921Impact of COVID-19 on neurological, psychological and other mental health outcomes (5,429 words) [view diff] no match in snippet view article find links to article
Neurology: A Mechanistic Insight". Combinatorial Chemistry & High Throughput Screening. 25 (5): 763–767. doi:10.2174/1386207324666210805121828. ISSN 1386-2073HIV vaccine development (5,624 words) [view diff] exact match in snippet view article find links to article
mechanism underlying promiscuous inhibitors from virtual and high-throughput screening". Journal of Medicinal Chemistry. 45 (8): 1712–22. doi:10.1021/jm010533yCobalamin riboswitch (2,354 words) [view diff] exact match in snippet view article find links to article
Zhang T, Zhu B, et al. (May 2018). "Engineering a vitamin B12 high-throughput screening system by riboswitch sensor in Sinorhizobium meliloti". BMC BiotechnologyHsp90 inhibitor (2,756 words) [view diff] no match in snippet view article find links to article
Medicinal Chemistry activities are focusing on the combined use of high throughput screening and structure-based design, coupled to the evaluation of the compoundsStuart Schreiber (3,391 words) [view diff] exact match in snippet view article find links to article
S2CID 39877841. Stockwell BR, Haggarty SJ, Schreiber SL (February 1999). "High-throughput screening of small molecules in miniaturized mammalian cell-based assaysJADE1 (6,055 words) [view diff] no match in snippet view article find links to article
(CK2). In addition, multiple phosphorylation sites are found by high throughput screening approaches and in silico analysis. Summary schematic for JADE1LDirected evolution (4,761 words) [view diff] exact match in snippet view article find links to article
traditional random mutagenesis library and so does not require such high-throughput screening. Creating a focused library requires some knowledge of which residuesFluorescence-activating and absorption-shifting tag (1,829 words) [view diff] exact match in snippet view article find links to article
reporters for cell identification, microbial cell biology and high-throughput screening of microbiota and genomic libraries". Current Opinion in BiotechnologyAntibody microarray (3,156 words) [view diff] exact match in snippet view article find links to article
Gorick, B. D., and Tomlinson, I. M. (2000) Antibody arrays for high-throughput screening of antibody-antigen interactions. Nature Biotechnol. 18, 989 –994Alternative splicing (7,813 words) [view diff] no match in snippet view article find links to article
alternatively spliced human pre-mRNAs". Combinatorial Chemistry & High Throughput Screening. 13 (3): 242–52. doi:10.2174/138620710790980522. PMC 3427726.Medicinal plants (8,315 words) [view diff] exact match in snippet view article find links to article
Walters MA (July 2014). "The essential roles of chemistry in high-throughput screening triage". Future Medicinal Chemistry. 6 (11): 1265–90. doi:10.4155/fmcShort linear motif (4,048 words) [view diff] no match in snippet view article find links to article
experimental, structural and evolutionary evidence. However, high throughput screening such as phage display has seen a large increase in the availableAli Ertürk (1,198 words) [view diff] exact match in snippet view article find links to article
Biotech's approach combines machine learning, network biology, and high-throughput screening to identify promising drug candidates and optimize their efficacyLigand binding assay (4,118 words) [view diff] exact match in snippet view article find links to article
PMID 3431465. Sittampalam GS, Kahl SD, Janzen WP (October 1997). "High-throughput screening: advances in assay technologies". Current Opinion in ChemicalSumit Chanda (1,018 words) [view diff] exact match in snippet view article find links to article
Martin-Sancho and Sumit K. Chanda" (PDF). Molecular Cell. June 17, 2021. "High-throughput screening reveals 21 drugs with activity against COVID-19" (Press release)Ozanimod (3,309 words) [view diff] exact match in snippet view article find links to article
et al. (June 2005). "S1P1-selective in vivo-active agonists from high-throughput screening: off-the-shelf chemical probes of receptor interactions, signalingHigh-resolution melting analysis (2,581 words) [view diff] no match in snippet view article find links to article
for use in diagnostics, due to its capacity to be adapted to high throughput screening testing, and again it minimises the possibility of amplicon spreadSamir Mitragotri (1,374 words) [view diff] exact match in snippet view article find links to article
4, 2004). "Discovery of transdermal penetration enhancers by high-throughput screening". Nature Biotechnology. 22 (2): 192–197. doi:10.1038/nbt928. PMID 14704682HIV (14,115 words) [view diff] exact match in snippet view article find links to article
mechanism underlying promiscuous inhibitors from virtual and high-throughput screening". Journal of Medicinal Chemistry. 45 (8): 1712–22. doi:10.1021/jm010533yDroplet-based microfluidics (23,775 words) [view diff] exact match in snippet view article find links to article
Microchip electrophoresis can be applied generally as a method for high-throughput screening processes that help discover and evaluate drugs. Using MCE, specificallyC22orf23 (1,794 words) [view diff] exact match in snippet view article find links to article
Chen RB (September 2015). "Quantitative proteomic analysis for high-throughput screening of differential glycoproteins in hepatocellular carcinoma serum"CREB-binding protein (5,272 words) [view diff] no match in snippet view article find links to article
Protein Implicated in Prostate Cancer". Combinatorial Chemistry & High Throughput Screening. 23 (3): 178–184. doi:10.2174/1386207323666200219122057. PMID 32072894GNMT (3,150 words) [view diff] case mismatch in snippet view article find links to article
as a Glycine N-Methyltransferase Enhancer by High-Throughput Screening of Natural Products Inhibits Hepatocellular Carcinoma". InternationalAmitriptyline (8,729 words) [view diff] exact match in snippet view article find links to article
Parkkisenniemi-Kinnunen UM, Xhaard H, Scheinin M, et al. (December 2012). "High-throughput screening with a miniaturized radioligand competition assay identifies newMetal–organic framework (21,470 words) [view diff] no match in snippet view article find links to article
media to separate gases with low energy cost using computational high throughput screening from their adsorption or gas breakthrough/diffusion propertiesCandida albicans (9,974 words) [view diff] exact match in snippet view article find links to article
been detected using this system in a low scale set up. A first high-throughput screening has also been performed. Interacting proteins can be found atFred Wudl (1,986 words) [view diff] no match in snippet view article find links to article
Ivanovskaya, Anna; Fan, Jie; Wudl, Fred; Stucky, Galen D. (2009). "High throughput screening and measurements of proton conductivity of newly developed PEMMosquito control (6,976 words) [view diff] exact match in snippet view article find links to article
discovery of new attractant compounds through molecular biology and high-throughput screening methods, aiming to develop more universally effective and durableX-ray crystallography (11,623 words) [view diff] no match in snippet view article find links to article
on membrane proteins: mini review". Combinatorial Chemistry & High Throughput Screening. 7 (5): 431–439. doi:10.2174/1386207043328634. PMID 15320710.McGill University Faculty of Engineering (4,624 words) [view diff] no match in snippet view article find links to article
molecular and cellular engineering; and biomedical, diagnostics and high throughput screening. The department of Mechanical is located in McGill's main downtownCarnation Italian ringspot virus (2,441 words) [view diff] exact match in snippet view article find links to article
detect CIRV-specific proteins. These assays are valuable for high-throughput screening of plant samples. The breeding and genetic modification of carnationCASS4 (3,332 words) [view diff] no match in snippet view article find links to article
pathologies, typically based on detection of changes in CASS4 in high throughput screening, although the role of CASS4 in the pathology of these conditionsPerturb-seq (2,588 words) [view diff] exact match in snippet view article find links to article
molecular biology to integrate a multi-step workflow that couples high-throughput screening with complex phenotypic outputs. When compared to alternativeZebrafish (12,241 words) [view diff] exact match in snippet view article find links to article
et al. (August 2013). "Robotic injection of zebrafish embryos for high-throughput screening in disease models". Methods. 62 (3): 246–254. doi:10.1016/j.ymethScanning electrochemical microscopy (5,218 words) [view diff] no match in snippet view article find links to article
multicomponent systems can be acquired on a rapid screening platform. Such high throughput screening significantly assists the search for abundant, efficient and cost-effectiveKinetic imaging (2,064 words) [view diff] no match in snippet view article find links to article
stow-aways. Unfortunately, no known technology is capable of high throughput screening of the large volume of cargo for hidden pests. However, the additionSystematic evolution of ligands by exponential enrichment (4,747 words) [view diff] no match in snippet view article find links to article
towards therapeutic applications". Combinatorial Chemistry & High Throughput Screening. 9 (8): 619–32. doi:10.2174/138620706778249695. PMID 17017882Cambridge Antibody Technology (8,496 words) [view diff] no match in snippet view article find links to article
and ProAb. ProAb was announced in December 1997 and involved high throughput screening of antibody libraries against diseased and non-diseased tissueList of mass spectrometry software (3,977 words) [view diff] no match in snippet view article find links to article
LC-MALDI-MS Based Peptide Profiling". Combinatorial Chemistry & High Throughput Screening. 8 (8): 717–23. doi:10.2174/138620705774962481. PMID 16464158Organoid (8,995 words) [view diff] exact match in snippet view article find links to article
direct from cancer tissue is now easily achievable and affords high-throughput screening of these tumors against the current panel of approved drugs formDevelopmental bioelectricity (17,264 words) [view diff] exact match in snippet view article find links to article
is gaining ground in the field with the possibility to allow high-throughput screening assays of the large combinatory outputs. Progress in molecularCanadian university scientific research organizations (7,008 words) [view diff] no match in snippet view article find links to article
Services Utilization Research Unit Health Information Research Unit High Throughput Screening Laboratory Independence and Economic Security of the Older PopulationCancer stem cell (10,356 words) [view diff] exact match in snippet view article find links to article
"Identification of selective inhibitors of cancer stem cells by high-throughput screening". Cell. 138 (4): 645–659. doi:10.1016/j.cell.2009.06.034. PMC 4892125List of model organisms (4,626 words) [view diff] exact match in snippet view article find links to article
Gabriele A.; Vilcinskas, Andreas; Grimm, Jan (24 November 2022). "High-throughput screening of caterpillars as a platform to study host–microbe interactionsAmbient ionization (5,967 words) [view diff] no match in snippet view article find links to article
Surfaces in Ionization Processes". Combinatorial Chemistry & High Throughput Screening. 12 (2): 125–136. doi:10.2174/138620709787315427. ISSN 1386-2073Marcin Hoffmann (2,981 words) [view diff] no match in snippet view article find links to article
"In silico prediction of SARS protease inhibitors by virtual high throughput screening". Chemical Biology & Drug Design. 69 (4): 269–79. doi:10.1111/jBiaxial tensile testing (4,993 words) [view diff] exact match in snippet view article find links to article
to perform GBT in parallel for an array of specimens enables high-throughput screening of mechanical properties and facilitates rapid materials designSplit and pool synthesis (3,913 words) [view diff] no match in snippet view article find links to article
Synthesis. A Theoretical Approach. Combinatorial Chemistry & High Throughput Screening 2000, 3, 197–209. Á. Furka US Patent 7/16/2002. Á Furka, G DibóMale contraceptive (15,337 words) [view diff] exact match in snippet view article find links to article
Jabloñski M, Balestrini PA, Novero AG, Torres NI, et al. (2023). "High-throughput screening method for discovering CatSper inhibitors using membrane depolarizationComposition of electronic cigarette aerosol (12,834 words) [view diff] exact match in snippet view article find links to article
2018). "Evaluation of e-liquid toxicity using an open-source high-throughput screening assay". PLOS Biology. 16 (3): e2003904. doi:10.1371/journal.pbioBimolecular fluorescence complementation (5,192 words) [view diff] exact match in snippet view article find links to article
& Burgess, R. R. Luminescence resonance energy transfer-based high-throughput screening assay for inhibitors of essential protein–protein interactionsRBM10 (5,530 words) [view diff] exact match in snippet view article find links to article
Damoiseaux R, Chen L, Black DL (June 2013). "A broadly applicable high-throughput screening strategy identifies new regulators of Dlg4 (Psd-95) alternativeThermal shift assay (5,887 words) [view diff] exact match in snippet view article find links to article
of folded protein in the starting material. This assay allows high-throughput screening of ligands to the target protein and it is widely used in theJose Luis Mendoza-Cortes (2,921 words) [view diff] exact match in snippet view article find links to article
"Transforming materials discovery for artificial photosynthesis: High-throughput screening of earth-abundant semiconductors". Journal of Applied PhysicsMyelinoid (4,897 words) [view diff] no match in snippet view article find links to article
difficult to scale myelinoid experiment to an appropriate scale for high throughput screening due to the long duration of protocols and limited efficiency.MicroRNA biosensors (7,163 words) [view diff] exact match in snippet view article find links to article
comprehensive monitoring during treatment while facilitating high-throughput screening. Second, it can significantly reduce cost and time by allowingOrganic residue analysis (7,621 words) [view diff] no match in snippet view article find links to article
Archaeology. 2/3: 20–25. Correa-Ascencio, M., Evershed, R. P. (2014). "High throughput screening of organic residues in archaeological potsherds using direct acidified