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searching for Pyridoxal phosphate 69 found (310 total)

Cysteine metabolism (492 words) [view diff] exact match in snippet view article find links to article

D-cysteine pyridoxal phosphate cysteine lyase → L-cysteate/hydrogen sulfide pyridoxal phosphate/sulfite cystathionine γ-lyase → pyruvate/NH3/H2S pyridoxal phosphate

GOT1 (793 words) [view diff] exact match in snippet view article find links to article

encoded by the GOT1 gene. Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and mitochondrial forms

Cystathioninuria (731 words) [view diff] exact match in snippet view article find links to article

important anti-oxidant, glutathione. Cystathionase has a co-enzyme, pyridoxal phosphate, which is the active form the vitamin B6. This means that vitamin

Aminotransferase, class V (168 words) [view diff] no match in snippet view article find links to article

mechanistic features with other pyridoxal- phosphate dependent enzymes, such as the covalent binding of the pyridoxal- phosphate group to a lysine residue.

Threo-3-hydroxy-D-aspartate ammonia-lyase (124 words) [view diff] no match in snippet view article find links to article

{\displaystyle \rightleftharpoons } oxaloacetate + NH3 This enzyme is a pyridoxal-phosphate protein. Maeda T, Takeda Y, Murakami T, Yokota A, Wada M (December

D-threonine aldolase (410 words) [view diff] no match in snippet view article find links to article

{\displaystyle \rightleftharpoons } glycine + acetaldehyde This pyridoxal-phosphate protein is activated by divalent metal cations (e.g. Co2+, Ni2+,

Phosphoserine transaminase (297 words) [view diff] no match in snippet view article find links to article

(3R)-3-hydroxy-2-oxo-4-phosphonooxybutanoate + L-glutamate This enzyme is a pyridoxal-phosphate protein. PSAT1 Hirsch H, Greenberg DM (May 1967). "Studies on phosphoserine

UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine transaminase (223 words) [view diff] no match in snippet view article find links to article

6-dideoxy-beta-L-arabino-hex-4-ulose + L-glutamate This enzyme is a pyridoxal-phosphate protein. Schoenhofen IC, McNally DJ, Vinogradov E, Whitfield D, Young

O-phospho-L-seryl-tRNASec:L-selenocysteinyl-tRNA synthase (302 words) [view diff] no match in snippet view article find links to article

selenophosphate ⇌ L-selenocysteinyl-tRNASec + phosphate This enzyme is pyridoxal-phosphate protein. Palioura S, Sherrer RL, Steitz TA, Söll D, Simonovic M (July

Pyridoxal phosphatase (205 words) [view diff] no match in snippet view article find links to article

pyridoxal 5′-phosphate + H2O ⇌ {\displaystyle \rightleftharpoons } pyridoxal + phosphate This enzyme belongs to the family of hydrolases, specifically those

3-hydroxy-D-aspartate aldolase (126 words) [view diff] no match in snippet view article find links to article

{\displaystyle \rightleftharpoons } glycine + glyoxylate This enzyme is a pyridoxal-phosphate protein. Liu JQ, Dairi T, Itoh N, Kataoka M, Shimizu S (July 2003)

Putrescine aminotransferase (214 words) [view diff] no match in snippet view article find links to article

\rightleftharpoons } 1-pyrroline + H2O (spontaneous) This enzyme is a pyridoxal-phosphate protein. Prieto-Santos MI, Martín-Checa J, Balaña-Fouce R, Garrido-Pertierra

5-phosphonooxy-L-lysine phospho-lyase (174 words) [view diff] no match in snippet view article find links to article

} (S)-2-amino-6-oxohexanoate + NH3 + phosphate This enzyme is a pyridoxal-phosphate protein. Tsai CH, Henderson LM (September 1974). "Degradation of

Low-specificity L-threonine aldolase (309 words) [view diff] exact match in snippet view article find links to article

\rightleftharpoons } glycine + acetaldehyde This enzyme requires pyridoxal phosphate. Yamada H, Kumagai H, Nagate T, Yoshida H (April 1970). "Crystalline

GCSH (1,457 words) [view diff] exact match in snippet view article find links to article

system (GCS), which is composed of 4 protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing

UDP-4-amino-4,6-dideoxy-N-acetyl-alpha-D-glucosamine transaminase (302 words) [view diff] no match in snippet view article find links to article

6-dideoxy-alpha-D-xylo-hex-4-ulose + L-glutamate This enzyme is a pyridoxal-phosphate protein. Olivier NB, Chen MM, Behr JR, Imperiali B (November 2006)

DTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose transaminase (167 words) [view diff] no match in snippet view article find links to article

dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose + L-glutamate This enzyme is a pyridoxal-phosphate protein. Pfoestl A, Hofinger A, Kosma P, Messner P (July 2003). "Biosynthesis

Group IV pyridoxal-dependent decarboxylases (315 words) [view diff] no match in snippet view article find links to article

which is known, in mouse ODC to be the site of attachment of the pyridoxal-phosphate group. The proteins also contain a stretch of three consecutive glycine

DTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose transaminase (179 words) [view diff] no match in snippet view article find links to article

dTDP-3-dehydro-6-deoxy-alpha-D-glucopyranose + L-glutamate This enzyme is a pyridoxal-phosphate protein. Melançon CE, Hong L, White JA, Liu YN, Liu HW (January 2007)

Zwitterion (1,106 words) [view diff] exact match in snippet view article find links to article

gained from the results of theoretical calculations. For example, pyridoxal phosphate, a form of vitamin B6, in aqueous solution is predicted to have an

Cys/Met metabolism PLP-dependent enzyme family (610 words) [view diff] exact match in snippet view article find links to article

PMID 24939187. Toney MD (January 2005). "Reaction specificity in pyridoxal phosphate enzymes". Arch. Biochem. Biophys. 433 (1): 279–87. doi:10.1016/j

Toxopyrimidine (133 words) [view diff] exact match in snippet view article find links to article

phosphate as an inhibitor of bacterial enzyme systems that require pyridoxal phosphate". The Biochemical Journal. 70 (4): 660–5. doi:10.1042/bj0700660.

Micronutrient deficiency (1,880 words) [view diff] exact match in snippet view article find links to article

1002/mnfr.201200477. PMID 23038656. The decarboyxlase enzymes have pyridoxal phosphate as a coenzyme, the form in which vitamin B6 occurs most commonly

Pyridoxal 5'-phosphate synthase (glutamine hydrolyzing) (447 words) [view diff] exact match in snippet view article

Dorrestein PC, Begley TP (March 2008). "Mechanistic studies on pyridoxal phosphate synthase: the reaction pathway leading to a chromophoric intermediate"

AGXT2 (455 words) [view diff] no match in snippet view article find links to article

aminotransferase 2. The protein encoded by this gene is a class III pyridoxal-phosphate-dependent mitochondrial aminotransferase. It catalyzes the conversion

Ruma Banerjee (342 words) [view diff] exact match in snippet view article find links to article

The coenzymes that she studies include vitamins B2 (flavin), B6 (pyridoxal phosphate), B12 (cobalamin), and heme, which support key junction enzymes that

PDXK (807 words) [view diff] exact match in snippet view article find links to article

ion binding metal ion binding kinase activity lithium ion binding pyridoxal phosphate binding ATP binding magnesium ion binding Cellular component cytosol

Indole test (573 words) [view diff] exact match in snippet view article find links to article

the reaction are indole, pyruvic acid, ammonium (NH4+) and energy. Pyridoxal phosphate is required as a coenzyme. Like many biochemical tests on bacteria

KYAT3 (62 words) [view diff] exact match in snippet view article find links to article

kynurenine-oxoglutarate transaminase activity catalytic activity lyase activity pyridoxal phosphate binding protein homodimerization activity kynurenine-glyoxylate transaminase

Pyridoxal kinase (198 words) [view diff] exact match in snippet view article find links to article

PMID 13773826. Trufanov AF; Krisanova JA. "Biosynthesis of pyridoxal phosphate by liver sections of rat in vitro". Byull. Eksp. Biol. Med. 22: 40–43

MOCOS (364 words) [view diff] exact match in snippet view article find links to article

ontology Molecular function transferase activity molybdenum ion binding pyridoxal phosphate binding protein binding catalytic activity Mo-molybdopterin cofactor

PROSC (351 words) [view diff] exact match in snippet view article find links to article

Gene ontology Molecular function pyridoxal phosphate binding Cellular component cytoplasm intracellular anatomical structure Biological process biological

AADAT (171 words) [view diff] exact match in snippet view article find links to article

Gene ontology Molecular function transferase activity pyridoxal phosphate binding kynurenine-oxoglutarate transaminase activity 2-aminoadipate transaminase

AGXT (964 words) [view diff] exact match in snippet view article find links to article

activity protein self-association catalytic activity protein binding pyridoxal phosphate binding signaling receptor binding identical protein binding Cellular

Serine hydroxymethyltransferase 2 (99 words) [view diff] exact match in snippet view article find links to article

identical protein binding glycine hydroxymethyltransferase activity pyridoxal phosphate binding zinc ion binding cobalt ion binding serine binding Cellular

Hyperprolinemia (1,133 words) [view diff] exact match in snippet view article find links to article

73–80. doi:10.1007/s11011-005-2478-x. PMID 15918552. S2CID 27367341. Pyridoxal phosphate de-activation by pyrroline-5-carboxylic acid. Increased risk of vitamin

GAD2 (290 words) [view diff] exact match in snippet view article find links to article

catalytic activity lyase activity protein heterodimerization activity pyridoxal phosphate binding carboxy-lyase activity glutamate binding glutamate decarboxylase

Aminodeoxychorismate lyase (381 words) [view diff] exact match in snippet view article find links to article

Escherichia coli pabC, the gene encoding aminodeoxychorismate lyase, a pyridoxal phosphate-containing enzyme". J. Bacteriol. 174 (16): 5317–23. doi:10.1128/jb

MARC2 (446 words) [view diff] exact match in snippet view article find links to article

cofactor binding molybdenum ion binding oxidoreductase activity pyridoxal phosphate binding nitrate reductase activity catalytic activity Cellular component

Aminodeoxychorismate lyase (381 words) [view diff] exact match in snippet view article find links to article

Escherichia coli pabC, the gene encoding aminodeoxychorismate lyase, a pyridoxal phosphate-containing enzyme". J. Bacteriol. 174 (16): 5317–23. doi:10.1128/jb

SGPL1 (491 words) [view diff] exact match in snippet view article find links to article

Molecular function protein binding catalytic activity lyase activity pyridoxal phosphate binding carboxy-lyase activity sphinganine-1-phosphate aldolase activity

YjeF N terminal protein domain (425 words) [view diff] exact match in snippet view article find links to article

that encode enzymes of diverse functions. Examples of such include: pyridoxal phosphate biosynthetic protein PdxJ; phosphopanteine-protein transferase; ATP/GTP

4-Deoxypyridoxine (506 words) [view diff] exact match in snippet view article find links to article

1981). "Effects of vitamin B-6 deficiency and 4'- deoxypyridoxine on pyridoxal phosphate concentrations, pyridoxine kinase and other aspects of metabolism

2,4-diaminopentanoate dehydrogenase (222 words) [view diff] exact match in snippet view article find links to article

acid via 2,4-diaminopentanoic acid; participation of B12 coenzyme, pyridoxal phosphate, and pyridine nucleotide". J. Biol. Chem. 245 (22): 5914–26. PMID 4394942

Dagmar Ringe (570 words) [view diff] exact match in snippet view article find links to article

February 20, 1942 (age 83) Nationality American Known for Structures of pyridoxal phosphate dependent enzymes, Solvent mapping as an approach to drug discovery

GADL1 (714 words) [view diff] exact match in snippet view article find links to article

ontology Molecular function sulfinoalanine decarboxylase activity pyridoxal phosphate binding catalytic activity carboxy-lyase activity aspartate 1-decarboxylase

KYAT1 (712 words) [view diff] exact match in snippet view article find links to article

lyase activity L-phenylalanine:pyruvate aminotransferase activity pyridoxal phosphate binding L-glutamine aminotransferase activity cysteine-S-conjugate

4-hydroxythreonine-4-phosphate dehydrogenase (309 words) [view diff] exact match in snippet view article find links to article

"Crystal structure of Escherichia coli PdxA, an enzyme involved in the pyridoxal phosphate biosynthesis pathway". J. Biol. Chem. 278 (44): 43682–90. doi:10

ALAS1 (1,075 words) [view diff] exact match in snippet view article find links to article

Gene ontology Molecular function transferase activity pyridoxal phosphate binding acyltransferase activity protein binding catalytic activity 5-aminolevulinate

Amine oxidase (copper-containing) (1,159 words) [view diff] exact match in snippet view article

PMID 5888801. Mondovi B, Costa MT, Agro AF, Rotilio G (1967). "Pyridoxal phosphate as a prosthetic group of pig kidney diamine oxidase". Arch. Biochem

Mitochondrial amidoxime reducing component 1 (460 words) [view diff] exact match in snippet view article find links to article

cofactor binding molybdenum ion binding oxidoreductase activity pyridoxal phosphate binding nitrate reductase activity catalytic activity Cellular component

Sideroblastic anemia (1,715 words) [view diff] exact match in snippet view article find links to article

sideroblastic anemia SLC25A38 206000 pyridoxine-responsive sideroblastic anemia (vitamin B6 deficiency; pyridoxal phosphate required for heme synthesis)

Tyrosine hydroxylase deficiency (748 words) [view diff] exact match in snippet view article find links to article

glycol; NMN, normetanephrine; PAH, phenylalanine hydroxylase; PLP, pyridoxal phosphate; PNMT, phenylethanolamine N-methyltransferase; TH, tyrosine hydroxylase;

ALAS2 (1,189 words) [view diff] exact match in snippet view article find links to article

transferase activity glycine binding protein binding catalytic activity pyridoxal phosphate binding acyltransferase activity 5-aminolevulinate synthase activity

GAD1 (1,125 words) [view diff] exact match in snippet view article find links to article

catalytic activity lyase activity protein heterodimerization activity pyridoxal phosphate binding carboxy-lyase activity glutamate binding glutamate decarboxylase

Alpha glucan (729 words) [view diff] exact match in snippet view article find links to article

plant and animal: interrelationship between the polysaccharide and pyridoxal phosphate binding sites by affinity electrophoresis". Biochemistry. 19 (11):

Wayne W. Umbreit (913 words) [view diff] exact match in snippet view article find links to article

I. C.; Umbreit, W. W. (1945). "Function of the vitamin B6 group: pyridoxal phosphate (codecarboxylase) in transamination" (PDF). Journal of Biological

Rostral ventromedial medulla (2,209 words) [view diff] no match in snippet view article find links to article

cells by ATP was reversed by using the P2 antagonists suramin and pyridoxal-phosphate-6-azophenyl-2′,4′disulphonic acid (PPADS), but not with the P2Y antagonist

Pyridoxine 5′-phosphate oxidase (1,439 words) [view diff] exact match in snippet view article find links to article

pyridoxal 5′-phosphate + NH3 + H2O2 pyridoxine phosphate + O2 ⇌ H2O2 + pyridoxal phosphate Pyridoxine 5′-phosphate oxidase also plays a role in nitrogen metabolism

Glycogen storage disease type V (6,656 words) [view diff] exact match in snippet view article find links to article

in certain mutations. For example, R138W is known to disrupt to pyridoxal phosphate binding site. In 2006, another mutation (c.13_14delCT) was discovered

Kynurenine pathway (2,408 words) [view diff] exact match in snippet view article find links to article

reduced. The activity was appreciably restored by the addition of pyridoxal phosphate. Downregulation of kynurenine 3-monooxygenase (KMO) can be caused

Citric acid cycle (6,064 words) [view diff] exact match in snippet view article find links to article

amino groups from glutamate in a transamination reaction, in which pyridoxal phosphate is a cofactor. In this reaction the glutamate is converted into alpha-ketoglutarate

Isoniazid (3,789 words) [view diff] exact match in snippet view article find links to article

Isoniazid is also associated with increased excretion of pyridoxine. Pyridoxal phosphate (a derivative of pyridoxine) is required for δ-aminolevulinic acid

Human serum albumin (4,056 words) [view diff] exact match in snippet view article find links to article

binding antioxidant activity protein binding identical protein binding pyridoxal phosphate binding copper ion binding lipid binding toxic substance binding

4-Amino-5-hydroxymethyl-2-methylpyrimidine (1,463 words) [view diff] exact match in snippet view article find links to article

in Candida albicans : a remarkable reaction between histidine and pyridoxal phosphate". Journal of the American Chemical Society. 134 (22): 9157–9. Bibcode:2012JAChS

Choline (6,039 words) [view diff] exact match in snippet view article find links to article

synthesize ethanolamine by direct decarboxylation of serine using a pyridoxal phosphate enzyme". The Journal of Biological Chemistry. 276 (38): 35523–9.

Cholera autoinducer-1 (1,823 words) [view diff] exact match in snippet view article find links to article

34 g/mol, with the formula C13H26O2. It is synthesized by CqsA, a pyridoxal phosphate dependent amintotransferase enzyme, but its role is not fully known

Cooperative binding (5,539 words) [view diff] exact match in snippet view article find links to article

Chinchilla D, Eisenstein E (April 1998). "Structure and control of pyridoxal phosphate dependent allosteric threonine deaminase". Structure. 6 (4): 465–75

Helicoverpa zea nudivirus 2 (4,485 words) [view diff] exact match in snippet view article find links to article

1955). "The interconversion of serine and glycine: participation of pyridoxal phosphate". The Biochemical Journal. 61 (2): 315–23. doi:10.1042/bj0610315