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searching for Phage display 76 found (162 total)

John McCafferty (735 words) [view diff] exact match in snippet view article find links to article

He is well known as one of the inventors of scFv antibody fragment phage display, a technology that revolutionised the monoclonal antibody drug discovery

Creative Biolabs (951 words) [view diff] exact match in snippet view article find links to article

discovery and development, including various phage display libraries such as pre-made libraries, phage display services, antibody sequencing, and antibody

Jane Osbourn (2,277 words) [view diff] case mismatch in snippet view article find links to article

Antibody Technology. CAT, as it was called, would pioneer the use of Phage Display technology that ultimately discovered important drugs such as Humira

Pancreatic lipase family (1,644 words) [view diff] exact match in snippet view article find links to article

orlistat can be used as a treatment for obesity. One peptide selected by phage display was found to inhibit pancreatic lipase. Orlistat (a pancreatic lipase

Erkki Ruoslahti (1,433 words) [view diff] exact match in snippet view article find links to article

that can be targeted by affinity ligands, and used in vivo peptide phage display to prove the concept and develop numerous tumor-homing peptides. Ruoslahti

Anti-sp100 antibodies (193 words) [view diff] no match in snippet view article find links to article

epitopes on the sp100 nuclear PBC autoantigen by the gene-fragment phage-display technology". Autoimmunity. 29 (1): 33–42. doi:10.3109/08916939908995970

Target-site overlap (577 words) [view diff] exact match in snippet view article find links to article

interpreting the zinc finger repertoires presented by investigations using ZFP phage display, it is important to appreciate the effects that the rest of the zinc

Phage monographs (4,280 words) [view diff] case mismatch in snippet view article find links to article

therapy, plus an editorial. Carnazza, S., Guglielmino, S. eds. 2010. Phage Display As a Tool for Synthetic Biology. Nova Science Publishers, Hauppauge

Lee Byung-heon (biochemist) (2,910 words) [view diff] exact match in snippet view article

research interest is “discovery of tissue-specific homing peptides using phage display and their applications to molecular imaging and targeted therapy”. He

Conformational epitope (291 words) [view diff] exact match in snippet view article find links to article

interactions: benchmark datasets and prediction tools evaluation EpiSearch, a new method to predict conformational epitopes using phage display peptide sequences

Kim Janda (1,978 words) [view diff] exact match in snippet view article find links to article

K. D. (May 25, 1999). "Making artificial antibodies: A format for phage display of combinatorial heterodimeric arrays". Proceedings of the National

Ekkehard Bautz (642 words) [view diff] exact match in snippet view article find links to article

transcription. Later, he focused on novel selection methods, in particular phage display and the generation of recombinant antibodies. In 1981, he founded the

SH3 domain (922 words) [view diff] exact match in snippet view article find links to article

Interaction Domains in Signal Transduction - The SH3 domain GENEART - Screen your protein against all human SH3 domains in a single phage display cycle

40S ribosomal protein S18 (693 words) [view diff] exact match in snippet view article find links to article

"Ribosomal protein S18 identified as a cofilin-binding protein by using phage display library". Mol. Cell. Biochem. 262 (1–2): 187–93. doi:10.1023/B:MCBI

BioPerl (1,192 words) [view diff] exact match in snippet view article find links to article

Gutteridge, A.; Honda, W.; Kanehisa, M. (2006). "MIMOX: A web tool for phage display based epitope mapping". BMC Bioinformatics. 7: 451. doi:10.1186/1471-2105-7-451

Colony picker (239 words) [view diff] exact match in snippet view article find links to article

and screening procedure on microplates for antibody generation from phage display libraries". J Biomol Screen. 14 (3): 282–93. doi:10.1177/1087057108330113

Heparan sulfate (4,151 words) [view diff] exact match in snippet view article find links to article

human monoclonal antibody with high affinity for heparan sulfate by phage display. The antibody binds heparan sulfate, not chondroitin sulfate. The binding

MASP2 (protein) (1,482 words) [view diff] exact match in snippet view article

(2010). "Selective inhibition of the lectin pathway of complement with phage display selected peptides against mannose-binding lectin-associated serine protease

Willem P. C. Stemmer (636 words) [view diff] exact match in snippet view article find links to article

he conducted postdoctoral research with Professor Fred Blattner on phage display of random peptide libraries and antibody fragment expression in E. coli

TRIB2 (923 words) [view diff] exact match in snippet view article find links to article

"Identification of tribbles homolog 2 as an autoantigen in autoimmune uveitis by phage display". Mol. Immunol. 42 (11): 1275–81. doi:10.1016/j.molimm.2004.11.020.

Annexin A11 (1,059 words) [view diff] exact match in snippet view article find links to article

using recombinant human annexin XI-specific autoantibodies cloned by phage display". The Journal of Biological Chemistry. 278 (35): 33120–6. doi:10.1074/jbc

PECR (485 words) [view diff] exact match in snippet view article find links to article

4-dienoyl-CoA reductase related protein using the M13 phage protein VI phage display technology". Comb Chem High Throughput Screen. 4 (7): 545–52. doi:10

Anti-Müllerian hormone receptor (1,298 words) [view diff] exact match in snippet view article find links to article

Adams GP (March 2008). "Isolation of anti-MISIIR scFv molecules from a phage display library by cell sorter biopanning". Cancer Immunology, Immunotherapy

LMBR1L (435 words) [view diff] exact match in snippet view article find links to article

a novel lipocalin-1 interacting human cell membrane receptor using phage display". J Biol Chem. 276 (23): 20206–12. doi:10.1074/jbc.M101762200. PMID 11287427

HMGB2 (1,190 words) [view diff] exact match in snippet view article find links to article

PMID 10490593. Butteroni C, De Felici M, Schöler HR, Pesce M (Dec 2000). "Phage display screening reveals an association between germline-specific transcription

Tartrate-resistant acid phosphatase (1,746 words) [view diff] exact match in snippet view article find links to article

Martinez DA, O'Keefe RJ, Rosier RN, Zuscik MJ, Puzas JE (January 2003). "A phage display technique identifies a novel regulator of cell differentiation". The

KLK14 (1,185 words) [view diff] no match in snippet view article find links to article

et al. (March 2005). "Enzymatic profiling of human kallikrein 14 using phage-display substrate technology". Biological Chemistry. 386 (3): 291–8. doi:10

Beta-2 microglobulin (2,117 words) [view diff] exact match in snippet view article find links to article

2f53: Directed Evolution of Human T-cell Receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without apparent

DHRS4 (461 words) [view diff] exact match in snippet view article find links to article

"Identification of peroxisomal proteins by using M13 phage protein VI phage display: molecular evidence that mammalian peroxisomes contain a 2,4-dienoyl-CoA

GRWD1 (490 words) [view diff] exact match in snippet view article find links to article

partners for the N-terminal domain of human topoisomerase I revealed by phage display". Molecular Biology Reports. 29 (4): 347–52. doi:10.1023/A:1021237021338

Zonadhesin (343 words) [view diff] exact match in snippet view article find links to article

sex hormone binding globulin-interacting proteins in the brain using phage display screening". Int. J. Mol. Med. 24 (4): 421–6. doi:10.3892/ijmm_00000248

Richard F. Heck (1,578 words) [view diff] case mismatch in snippet view article find links to article

Sequence-Specific Palladium-Mediated Cross-Coupling Reaction Identified from Phage Display". ACS Chemical Biology. 9 (9): 2139–2148. doi:10.1021/cb500443x. PMC 4168780

Retrogenix (792 words) [view diff] exact match in snippet view article find links to article

Hudecek M & Rader C (2017). "Mining naïve rabbit antibody repertoires by phage display for monoclonal antibodies of therapeutic utility". Journal of Molecular

RESF1 (1,434 words) [view diff] exact match in snippet view article find links to article

lymph node. MDM2 was found to interact with RESF1 through the use of a phage display library. This interaction further suggests that RESF1 is a nuclear protein

Growth hormone receptor (1,925 words) [view diff] case mismatch in snippet view article find links to article

GROWTH HORMONE MUTANT G120R WITH ITS SOLUBLE BINDING PROTEIN 1kf9: PHAGE DISPLAY DERIVED VARIANT OF HUMAN GROWTH HORMONE COMPLEXED WITH TWO COPIES OF

CD48 (2,192 words) [view diff] exact match in snippet view article find links to article

human CD48 and isolation of a human anti-CD48 monoclonal antibody by phage display". Journal of Chemical Technology and Biotechnology. 80 (7): 782–795

MASP1 (protein) (2,168 words) [view diff] exact match in snippet view article

2010). "Selective inhibition of the lectin pathway of complement with phage display selected peptides against mannose-binding lectin-associated serine protease

Calcium pyrophosphate dihydrate crystal deposition disease (1,437 words) [view diff] case mismatch in snippet view article find links to article

Wieczorek RM, Marzec N, Garstka M, Misicka A (September 2021). "A Phage Display-Identified Short Peptide Capable of Hydrolyzing Calcium Pyrophosphate

HLA-A (3,411 words) [view diff] exact match in snippet view article find links to article

2f53: Directed Evolution of Human T-cell Receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without apparent

Glypican 4 (584 words) [view diff] exact match in snippet view article find links to article

Schwarz EM, O'Keefe RJ, Rosier RN, Puzas JE (May 2002). "Use of a phage display technique to identify potential osteoblast binding sites within osteoclast

FCER1A (1,096 words) [view diff] case mismatch in snippet view article find links to article

FC(EPSILON)RI(ALPHA), TETRAGONAL CRYSTAL FORM 2 1rpq: High Affinity IgE Receptor (alpha chain) Complexed with Tight-Binding E131 'zeta' Peptide from Phage Display

T cell receptor T cell therapy (601 words) [view diff] exact match in snippet view article find links to article

screened out, leaving only those unique to the tumorous cells. Then a TCR phage display library is used to pick TCRs with high affinity and specificity. A preclinical

Eukaryotic translation elongation factor 1 alpha 1 (2,672 words) [view diff] exact match in snippet view article find links to article

J, Shibata H, McDonnell DP, Clyne CD, Young MJ (Sep 2014). "Use of phage display to identify novel mineralocorticoid receptor-interacting proteins".

Epidermal growth factor (1,735 words) [view diff] exact match in snippet view article find links to article

N-terminus of epidermal growth factor in ErbB-2/ErbB-3 binding studied by phage display". Biochemistry. 41 (27): 8732–41. doi:10.1021/bi025878c. PMID 12093292

FGFBP1 (800 words) [view diff] exact match in snippet view article find links to article

factor (FGF)-interacting domain in a secreted FGF-binding protein by phage display". J. Biol. Chem. 281 (2): 1137–44. doi:10.1074/jbc.M510754200. PMID 16257968

Alanine scanning (820 words) [view diff] exact match in snippet view article find links to article

concepts of alanine scanning mutagenesis and binomial mutagenesis with phage display technology was used. Another critical application of alanine scanning

Synthetic antibody (1,198 words) [view diff] exact match in snippet view article find links to article

authors list (link) Hammers, C.M. and Stanley, J.R. (2014). "Antibody phage display: Technique and applications". J. Invest. Dermatol. 134 (2): 1–5. doi:10

Peter G. Schultz (2,084 words) [view diff] no match in snippet view article find links to article

Richard Lerner, he was one of the critical players in the development of phage-display libraries, and surface-library chips. For high-throughput bioassays

GJB6 (2,915 words) [view diff] exact match in snippet view article find links to article

Targan SR, Iwanczyk L, Vidrich A, Gordon LK, Braun J (May 1996). "Phage display cloning and characterization of an immunogenetic marker (perinuclear

Racemic crystallography (1,480 words) [view diff] exact match in snippet view article find links to article

factor A (VEGF-A). The mirror image D-protein form of VEGF-A was used in phage display to identify a 56 residue L-protein binder with nanomolar affinity; the

Growth hormone 1 (404 words) [view diff] case mismatch in snippet view article find links to article

GROWTH HORMONE MUTANT G120R WITH ITS SOLUBLE BINDING PROTEIN 1kf9: PHAGE DISPLAY DERIVED VARIANT OF HUMAN GROWTH HORMONE COMPLEXED WITH TWO COPIES OF

Carlos F. Barbas III (872 words) [view diff] exact match in snippet view article find links to article

laboratory manual of antibody phage with his colleagues at Scripps. The phage display is the most straightforward technique to study the interactions between

Lipocalin 1 (1,463 words) [view diff] exact match in snippet view article find links to article

a novel lipocalin-1 interacting human cell membrane receptor using phage display". The Journal of Biological Chemistry. 276 (23): 20206–12. doi:10.1074/jbc

CD97 (3,476 words) [view diff] exact match in snippet view article find links to article

Mulkearns-Hubert EE, Man J, Hjelmeland AB, Yu J, Lathia JD, Rich JN (Aug 2014). "Phage display discovery of novel molecular targets in glioblastoma-initiating cells"

ARAF (1,985 words) [view diff] exact match in snippet view article find links to article

PMID 10848612. King TR, Fang Y, Mahon ES, Anderson DH (2000). "Using a phage display library to identify basic residues in A-Raf required to mediate binding

Phytaspase (684 words) [view diff] exact match in snippet view article find links to article

P. N. (1998-11-01). "Stabilizing the subtilisin BPN' pro-domain by phage display selection: how restrictive is the amino acid code for maximum protein

Antibody (13,262 words) [view diff] exact match in snippet view article find links to article

like animal immunization and various in vitro approaches, such as the phage display method. Traditionally, most antibodies are produced by hybridoma cell

Phi X 174 (2,296 words) [view diff] exact match in snippet view article find links to article

bloodborne viruses. ΦX174 has also been modified to enable peptide display (phage display) from the viral capsid G protein. The ΦX174 genome was the first phage

Oct-4 (4,089 words) [view diff] exact match in snippet view article find links to article

PMID 11096094. Butteroni C, De Felici M, Schöler HR, Pesce M (December 2000). "Phage display screening reveals an association between germline-specific transcription

W. Ian Lipkin (6,008 words) [view diff] exact match in snippet view article find links to article

presence of antibodies to enterovirus in AFM patient CSF samples using phage display (VirScan). "It's always good to see reproducibility. It gives more confidence

Timeline of women in science in the United States (2,770 words) [view diff] exact match in snippet view article find links to article

shared it with George Smith and Gregory Winter, who received it "for the phage display of peptides and antibodies". This made Frances the first American woman

Mesothelin (2,785 words) [view diff] exact match in snippet view article find links to article

monoclonal antibodies HN1 and SD1 targeting mesothelin have been isolated by phage display. Mitchell Ho and Ira Pastan at the U.S. National Institutes of Health

Oncomatryx (1,688 words) [view diff] exact match in snippet view article find links to article

the tumor stroma marker "fibroblast activation protein" selected by phage display from an immunized FAP-/- knock-out mouse". Molecular Medicine. 7 (7):

Short linear motif (4,048 words) [view diff] exact match in snippet view article find links to article

and evolutionary evidence. However, high throughput screening such as phage display has seen a large increase in the available information for many motifs

Watershed stroke (3,828 words) [view diff] exact match in snippet view article find links to article

focal cerebral ischemia using a homing peptide selected from in vivo phage display". Journal of Controlled Release. 131 (3): 167–72. doi:10.1016/j.jconrel

Epidermal growth factor receptor (6,879 words) [view diff] exact match in snippet view article find links to article

N-terminus of epidermal growth factor in ErbB-2/ErbB-3 binding studied by phage display". Biochemistry. 41 (27): 8732–41. doi:10.1021/bi025878c. PMID 12093292

Matrilin-3 (2,170 words) [view diff] exact match in snippet view article find links to article

et al. (2007). "Identification of an ADAMTS-4 cleavage motif using phage display leads to the development of fluorogenic peptide substrates and reveals

Estrogen receptor alpha (6,357 words) [view diff] no match in snippet view article find links to article

box II peptide 2bj4: ESTROGEN RECEPTOR ALPHA LBD IN COMPLEX WITH A PHAGE-DISPLAY DERIVED PEPTIDE ANTAGONIST 2fai: Human Estrogen Receptor Alpha Ligand-Binding

Moein Moghimi (2,683 words) [view diff] exact match in snippet view article find links to article

blood-brain-barrier with nanoligand drug carriers self-assembled from a phage display peptide". Nature Communications. 10 (1): 4635. Bibcode:2019NatCo..10

Quantum dot (13,191 words) [view diff] exact match in snippet view article find links to article

semiconductor surfaces through the method of selection by combinatorial phage display. Additionally, it is known that liquid crystalline structures of wild-type

Jasna Rakonjac (834 words) [view diff] exact match in snippet view article find links to article

Marjorie Russel (18 April 2011). "Filamentous bacteriophage: biology, phage display and nanotechnology applications". Current Issues in Molecular Biology

Bill Harris (geneticist) (1,627 words) [view diff] exact match in snippet view article

those provided by traditional monoclonals through the use of antibody phage display libraries and combinatorial libraries based upon novel scaffolds. to

Riccardo Cortese (2,833 words) [view diff] exact match in snippet view article find links to article

drugs and vaccines for the treatment of infectious diseases. He used Phage display technology to isolate peptides for diagnostic and vaccination purposes

Functional cloning (3,006 words) [view diff] exact match in snippet view article find links to article

novel strategy for the functional cloning of enzymes using filamentous phage display: the case of nucleotidyl transferases Oxford Journals] Molecular genetics

Timeline of women in science (19,005 words) [view diff] exact match in snippet view article find links to article

shared it with George Smith and Gregory Winter, who received it "for the phage display of peptides and antibodies". This made Frances the first American woman

2018 in science (22,287 words) [view diff] exact match in snippet view article find links to article

evolution of enzymes", George P. Smith and Gregory P. Winter, "for the phage display of peptides and antibodies" January 5 – Thomas Bopp, American astronomer