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searching for Effector cell 42 found (52 total)

Activation-induced cell death (434 words) [view diff] exact match in snippet view article find links to article

Alteration of the process may lead to autoimmune diseases. The AICD effector cell is one that expresses FasL, and apoptosis is induced in the cell expressing

EPR1 (544 words) [view diff] exact match in snippet view article find links to article

Effector cell peptidase receptor 1, also known as EPR1, is a withdrawn database record. This locus represents an antisense transcript of the survivin

CCL28 (751 words) [view diff] exact match in snippet view article find links to article

pro-inflammatory cytokines and certain bacterial products implying a role in effector cell recruitment to sites of epithelial injury. CCL28 has also been implicated

B cell (3,748 words) [view diff] exact match in snippet view article find links to article

antigen, it proliferates and differentiates into an antibody-secreting effector cell, known as a plasmablast or plasma cell. In addition, B cells present

Synapse (4,320 words) [view diff] exact match in snippet view article find links to article

pass an electrical or chemical signal to another neuron or a target effector cell. Synapses can be chemical or electrical. In the case of electrical synapses

Immunodominance (1,086 words) [view diff] exact match in snippet view article find links to article

thousands of different peptides from the proteins of pathogens. Yet, the effector cell population that is reactive against the pathogen is dominated by cells

Pseudoallergy (1,411 words) [view diff] exact match in snippet view article find links to article

hypersensitivity in the Gell and Coombs classification in that the effector cell is also mast cell. In pseudoallergic reaction, the mast cell is directly

Obecabtagene autoleucel (560 words) [view diff] exact match in snippet view article find links to article

bacterial infectious disorders, diarrhea, febrile neutropenia, immune effector cell-associated neurotoxicity syndrome, hypotension, pain, fatigue, headache

CAR T cell (8,772 words) [view diff] no match in snippet view article find links to article

In biology, chimeric antigen receptors (CARs)—also known as chimeric immunoreceptors, chimeric T cell receptors or artificial T cell receptors—are receptor

Nef (protein) (1,133 words) [view diff] exact match in snippet view article

of the infected cell by IL-2 also stimulates the cell to become an effector cell and initiate the machinery which HIV-1 relies upon for its own proliferation

Antibody opsonization (641 words) [view diff] exact match in snippet view article find links to article

does not need to be internalised to be destroyed. ADCC requires an effector cell with the ability to eliminate pathogens through release of cytotoxic

Matuzumab (842 words) [view diff] exact match in snippet view article find links to article

the epidermal growth factor receptor: immunologically mediated and effector cell-independent effects". Cancer Research. 47 (14): 3692–6. PMID 3297307

Immune checkpoint (3,473 words) [view diff] exact match in snippet view article find links to article

lymphocytes and dendritic cells. CD27 costimulation is known to suppress Th17 effector cell function. The American biotech company Celldex Therapeutics is working

Teclistamab (1,166 words) [view diff] exact match in snippet view article find links to article

cytokine release syndrome (CRS) and neurologic toxicity, including immune effector cell-associated neurotoxicity (ICANS). Among people who received teclistamab

Lymphotoxin (1,459 words) [view diff] exact match in snippet view article find links to article

receptor on the target cell can activate various signaling pathways in the effector cell such as the activation of the NF-κB pathway, a major signaling pathway

Survivin (8,391 words) [view diff] exact match in snippet view article find links to article

Library of Medicine. Altieri DC (February 1994). "Molecular cloning of effector cell protease receptor-1, a novel cell surface receptor for the protease

TOX (1,814 words) [view diff] exact match in snippet view article find links to article

TOX2-deficient tumor-specific CAR T cells additionally have increased antitumor effector cell function as well as decreased levels of inhibitory receptors. NFAT transcription

SERPINB9 (1,045 words) [view diff] exact match in snippet view article find links to article

proteinase inhibitor 9, is up-regulated during accessory cell maturation and effector cell degranulation, and its overexpression enhances CTL potency". J. Immunol

Talin (protein) (1,874 words) [view diff] exact match in snippet view article

cytoplasmic organelles and the membrane-associated cytoskeleton in the effector cell". The Journal of Experimental Medicine. 163 (3): 489–98. doi:10.1084/jem

Cell polarity (2,558 words) [view diff] exact match in snippet view article find links to article

neurotransmitters are released to propagate the signal to another neuron or effector cell (e.g., muscle or gland). The polarity of the neuron thus facilitates

Monoclonal antibody (4,964 words) [view diff] exact match in snippet view article find links to article

with their Fab regions both to target antigen and to a conjugate or effector cell. Every intact antibody can bind to cell receptors or other proteins

Natural killer cell (9,227 words) [view diff] exact match in snippet view article find links to article

published similar data with respect to the unique nature of the mouse effector cell. The human data were confirmed, for the most part, by West et al. using

Gene Shearer (2,072 words) [view diff] exact match in snippet view article find links to article

mediated lympholysis to trinitrophenyl modified autologous lymphocytes: Effector cell specificity to modified cell surface components controlled by the H

Shane Crotty (1,128 words) [view diff] case mismatch in snippet view article find links to article

S (2011). "ICOS Receptor Instructs T Follicular Helper Cell versus Effector Cell Differentiation via Induction of the Transcriptional Repressor Bcl6"

GEMoaB Monoclonals (726 words) [view diff] exact match in snippet view article find links to article

can be rapidly turned off after TM withdrawal, promising to avoid T-effector cell exhaustion and to reduce potential side effects typically associated

Adaptive immune system (7,168 words) [view diff] exact match in snippet view article find links to article

T cell (predominately Th2 type)), it further differentiates into an effector cell, known as a plasma cell. Plasma cells are short-lived cells (2–3 days)

Index of oncology articles (5,119 words) [view diff] exact match in snippet view article find links to article

ectocervical – edatrexate – edotecarin – edrecolomab – efaproxiral – effector cell – efficacy – eflornithine – EGb761 – EGFR – EKB-569 – electroacupuncture

Tarlatamab (518 words) [view diff] exact match in snippet view article find links to article

cytokine release syndrome (CRS) and neurologic toxicity, including immune effector cell-associated neurotoxicity syndrome (ICANS). The most common adverse reactions

Gamma delta T cell (4,472 words) [view diff] case mismatch in snippet view article find links to article

S2CID 4937603. Shiromizu CM, Jancic CC (16 October 2018). "γδ T Lymphocytes: An Effector Cell in Autoimmunity and Infection". Frontiers in Immunology. 9: 2389. doi:10

Hepatocyte growth factor receptor (6,727 words) [view diff] exact match in snippet view article find links to article

forming a bridge between an effector and a target cells. This induces the effector cell activation, leading to phagocytosis of the tumor cell by neutrophils

Tumor microenvironment (6,977 words) [view diff] exact match in snippet view article find links to article

toxicity profile, including cytokine release syndrome (CRS), immune effector cell-associated neurotoxicity syndrome (ICANS), and cytopenias, becomes increasingly

Regulatory T cell (9,481 words) [view diff] exact match in snippet view article find links to article

that receives a weak signal will survive and be selected to become an effector cell. If a T cell receives an intermediate signal, then it will become a

KHYG-1 (1,016 words) [view diff] exact match in snippet view article find links to article

study of the mechanism of NK cell leukemogenesis and as a potential effector cell in NK cell-mediated cancer immunotherapy. In recent years there have

Cellular adoptive immunotherapy (2,170 words) [view diff] exact match in snippet view article find links to article

still lack well-explained pathogenesis [3]. Furthermore, the immune effector cell-associated neurotoxicity can cause death occasionally. Some hypothesized

Afamitresgene autoleucel (894 words) [view diff] exact match in snippet view article find links to article

decreased, and platelet count decreased. Recipients may also exhibit immune effector cell-associated neurotoxicity syndrome (ICANS), an immune system-related

Inflammasome (7,823 words) [view diff] exact match in snippet view article find links to article

cell death, (2) release of soluble pro-inflammatory molecules, and (3) effector cell recruitment and activation. In addition, epithelial inflammasome activation

He Jiankui affair (12,426 words) [view diff] exact match in snippet view article find links to article

milestone in the development and clinical application of gene-edited effector cell therapy," it was far from curing the diseases. One died after the clinical

Elranatamab (821 words) [view diff] exact match in snippet view article find links to article

cytokine release syndrome and neurologic toxicity, including immune effector cell-associated neurotoxicity. The safety and effectiveness of elranatamab

Talquetamab (1,157 words) [view diff] exact match in snippet view article find links to article

cytokine release syndrome and neurologic toxicity, including immune effector cell-associated neurotoxicity. In 2024, the molecular structure of GPRC5D

Innate lymphoid cell (10,510 words) [view diff] exact match in snippet view article find links to article

named ‘common helper like’ due to their similarity to the T helper effector cell fates. Each stage of differentiation is dependent on expression of different

Zanvil A. Cohn (4,965 words) [view diff] exact match in snippet view article find links to article

86:304-314. With C. F. Nathan and H. W. Murray. The macrophage as an effector cell. N. Engl. J. Med. 303:622-626. With W. A. Scott, J. M. Zrike, A. L.

Epigenetics of autoimmune disorders (7,834 words) [view diff] exact match in snippet view article find links to article

DNA methylation variability in type 1 diabetes across three immune effector cell types". Nature Communications. 7 (1): 13555. Bibcode:2016NatCo...713555P