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Longer titles found: Planar cell polarity (view), Prickle planar cell polarity protein 2 (view), Wd repeat containing planar cell polarity effector (view)

searching for Cell polarity 364 found (441 total)

alternate case: cell polarity

Flamingo (protein) (804 words) [view diff] exact match in snippet view article

was originally identified as a Drosophila protein involved in planar cell polarity. Mammals have three flamingo homologs, CELSR1, CELSR2, CELSR3. In mice

Dishevelled (1,387 words) [view diff] exact match in snippet view article find links to article

the embryo and the adult, ranging from cellular differentiation and cell polarity to social behavior. There are three human genes that encode for the

Receptor tyrosine kinase-like orphan receptor (85 words) [view diff] exact match in snippet view article find links to article

in regulating skeletal and neuronal development, cell migration and cell polarity. ROR proteins (ROR1 and ROR2 in humans) can modulate Wnt signaling by

PARD3 (1,122 words) [view diff] exact match in snippet view article find links to article

polarized growth, whereas CDC42 (MIM 116952) mediates the establishment of cell polarity. The CDC42 GTPase, which is controlled by nucleotide exchange factors

PARD6B (593 words) [view diff] exact match in snippet view article find links to article

Sumimoto H (March 2001). "Human homologues of the Caenorhabditis elegans cell polarity protein PAR6 as an adaptor that links the small GTPases Rac and Cdc42

STK11 (2,791 words) [view diff] exact match in snippet view article find links to article

which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumour suppressor. LKB1 is a primary upstream kinase

Frizzled-3 (802 words) [view diff] exact match in snippet view article find links to article

derived from mouse studies. Fzd3 in the mouse functions through planar cell polarity signaling instead of the canonical Wnt/beta-catenin pathway. Fzd3 controls

Protein Wnt-5a (3,404 words) [view diff] exact match in snippet view article find links to article

Biological process somitogenesis cellular response to retinoic acid planar cell polarity pathway involved in outflow tract morphogenesis excitatory synapse assembly

Fucus (1,772 words) [view diff] exact match in snippet view article find links to article

zygotes, several Fucus species have been used as model organisms to study cell polarity, the development of growth axes, and the role of the cell wall in establishing

Prickle (protein) (923 words) [view diff] exact match in snippet view article

of the non-canonical Wnt signaling pathway that establishes planar cell polarity. A gain or loss of function of Prickle1 causes defects in the convergent

Cell growth (4,893 words) [view diff] exact match in snippet view article find links to article

Cdr2-dependent negative regulation of Wee1 at the medial cortical nodes. Cell polarity factors positioned at the cell tips provide spatial cues to limit Cdr2

Centre for Genomic Regulation (905 words) [view diff] exact match in snippet view article find links to article

networks, and the effect of stochastic noise at the organism level. Cell polarity is a prerequisite for several fundamental operations in animal cells

Caulobacter crescentus (3,357 words) [view diff] exact match in snippet view article find links to article

gives rise to morphologically similar daughter cells. In C. crescentus, cell polarity is readily apparent by the assembly of polar organelles and by the polarization

PARD6A (1,395 words) [view diff] exact match in snippet view article find links to article

Sumimoto H (March 2001). "Human homologues of the Caenorhabditis elegans cell polarity protein PAR6 as an adaptor that links the small GTPases Rac and Cdc42

PARD3B (593 words) [view diff] exact match in snippet view article find links to article

Takeuchi K, Sumimoto H (Dec 2002). "PAR3beta, a novel homologue of the cell polarity protein PAR3, localizes to tight junctions". Biochem Biophys Res Commun

PRICKLE1 (618 words) [view diff] exact match in snippet view article find links to article

Prickle planar cell polarity protein 1 is a protein that in humans is encoded by the PRICKLE1 gene. This gene encodes a nuclear receptor that may be a

MARK2 (1,143 words) [view diff] exact match in snippet view article find links to article

small family of ser/thr protein kinases involved in the control of cell polarity, microtubule stability and cancer. Several cDNA clones have been isolated

F11 receptor (1,329 words) [view diff] exact match in snippet view article find links to article

JAM-2 and JAM-3 associate with the cell polarity protein PAR-3: a possible role for JAMs in endothelial cell polarity". Journal of Cell Science. 116 (Pt

Frizzled (809 words) [view diff] exact match in snippet view article find links to article

sponges to humans. Frizzled proteins also play key roles in governing cell polarity, embryonic development, formation of neural synapses, cell proliferation

JAM3 (1,137 words) [view diff] exact match in snippet view article find links to article

JAM-2 and JAM-3 associate with the cell polarity protein PAR-3: a possible role for JAMs in endothelial cell polarity". J. Cell Sci. 116 (Pt 19): 3879–91

FMNL1 (610 words) [view diff] exact match in snippet view article find links to article

Formin-related proteins have been implicated in morphogenesis, cytokinesis, and cell polarity. An alternative splice variant has been described but its full length

Strabismus (protein) (406 words) [view diff] exact match in snippet view article

was originally identified as a Drosophila protein involved in planar cell polarity. Flies with mutated strabismus genes have altered development of ommatidia

Septin (3,025 words) [view diff] exact match in snippet view article find links to article

These protein complexes are involved in cytokinesis, chitin deposition, cell polarity, spore formation, in the morphogenesis checkpoint, spindle alignment

CELSR1 (731 words) [view diff] exact match in snippet view article find links to article

orientation planar cell polarity pathway involved in neural tube closure multicellular organism development Wnt signaling pathway, planar cell polarity pathway central

Frizzled-1 (587 words) [view diff] exact match in snippet view article find links to article

DNA-binding transcription factor activity Wnt signaling pathway planar cell polarity pathway involved in neural tube closure negative regulation of BMP signaling

ZIC3 (1,047 words) [view diff] exact match in snippet view article find links to article

defects caused by loss of Zic3 have been linked to defective planar cell polarity. ZIC3 is also of particular interest as it has been shown to be required

Frizzled-2 (592 words) [view diff] exact match in snippet view article find links to article

DNA-binding transcription factor activity Wnt signaling pathway planar cell polarity pathway involved in neural tube closure positive regulation of transcription

CELSR3 (555 words) [view diff] exact match in snippet view article find links to article

localization multicellular organism development Wnt signaling pathway, planar cell polarity pathway cell surface receptor signaling pathway cell adhesion axonal

LLGL1 (657 words) [view diff] exact match in snippet view article find links to article

complex with PAR-6 and aPKC independently of PAR-3 to regulate epithelial cell polarity". Curr. Biol. 13 (9): 734–43. doi:10.1016/S0960-9822(03)00244-6. PMID 12725730

STAU1 (2,553 words) [view diff] exact match in snippet view article find links to article

mitosis. A variety of cell polarity proteins are classified as tumor suppressors or proto-oncogenes as a disruption of cell polarity has been linked to cancer

Zhang Mingjie (345 words) [view diff] exact match in snippet view article find links to article

regulation of neuronal signaling complexes and machineries in controlling cell polarity by using protein crystallography and NMR spectroscopy. In 2006, his

NPHP3 (590 words) [view diff] exact match in snippet view article find links to article

gastrulation ureter development regulation of Wnt signaling pathway, planar cell polarity pathway negative regulation of canonical Wnt signaling pathway epithelial

FGD1 (1,607 words) [view diff] exact match in snippet view article find links to article

exchange on the GTPase Cdc42, a key player in the establishment of cell polarity in all eukaryotic cells. The GEF activity of FGD1, which activates Cdc42

WNT11 (782 words) [view diff] exact match in snippet view article find links to article

fiber assembly planar cell polarity pathway involved in gastrula mediolateral intercalation Wnt signaling pathway, planar cell polarity pathway Wnt signaling

WNT9B (437 words) [view diff] exact match in snippet view article find links to article

Chirumamilla R, Aoki S, et al. (2009). "Wnt9b signaling regulates planar cell polarity and kidney tubule morphogenesis". Nat Genet. 41 (7): 793–799. doi:10

CRB3 (451 words) [view diff] exact match in snippet view article find links to article

Crumbs family of proteins. This protein may play a role in epithelial cell polarity and is associated with tight junctions at the apical surface of epithelial

David G. Drubin (1,434 words) [view diff] exact match in snippet view article find links to article

study its biological function. He distilled general principles for cell polarity development while defining it as the ultimate reflection of complex

ROR2 (1,123 words) [view diff] exact match in snippet view article find links to article

binding coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway mitogen-activated protein kinase kinase kinase binding receptor

ALS2CR2 (789 words) [view diff] exact match in snippet view article find links to article

activation of serine/threonine kinase 11, a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation

Pseudopodia (1,740 words) [view diff] exact match in snippet view article find links to article

Lani F.; Weiner, Orion D. (2012-01-20). "Membrane tension maintains cell polarity by confining signals to the leading edge during neutrophil migration"

InaD-like protein (933 words) [view diff] exact match in snippet view article find links to article

"Structural basis for L27 domain-mediated assembly of signaling and cell polarity complexes". EMBO J. 23 (14): 2723–33. doi:10.1038/sj.emboj.7600294.

Related to receptor tyrosine kinase (893 words) [view diff] exact match in snippet view article find links to article

binding coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway receptor tyrosine kinase transmembrane receptor protein tyrosine

ROR1 (1,200 words) [view diff] exact match in snippet view article find links to article

activity coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway Wnt-activated receptor activity receptor tyrosine kinase transmembrane

DVL1 (1,276 words) [view diff] exact match in snippet view article find links to article

2003). "Identification of three novel Smad binding proteins involved in cell polarity". FEBS Lett. 539 (1–3): 167–73. Bibcode:2003FEBSL.539..167W. doi:10

NPHP1 (1,198 words) [view diff] exact match in snippet view article find links to article

epithelial cell-cell junctions, interaction with filamins, and establishing cell polarity". The Journal of Biological Chemistry. 277 (32): 29028–35. doi:10.1074/jbc

Mitotic exit (3,412 words) [view diff] exact match in snippet view article find links to article

concepts of cell polarity and mitotic regulation. Central to this network are the roles of Cdc14, a cell cycle phosphatase, and various cell polarity proteins

CRB1 (1,150 words) [view diff] exact match in snippet view article find links to article

Identifiers Aliases CRB1, LCA8, RP12, crumbs 1, cell polarity complex component, crumbs cell polarity complex component 1, CRB1-B, CRB1-C, CRB1-A External

PRKCI (1,731 words) [view diff] exact match in snippet view article find links to article

Takeuchi K, Sumimoto H (Dec 2002). "PAR3beta, a novel homologue of the cell polarity protein PAR3, localizes to tight junctions". Biochemical and Biophysical

Chonnettia Jones (426 words) [view diff] exact match in snippet view article find links to article

of Addgene. Jones, Chonnettia; Chen, Ping (February 2007). "Planar cell polarity signaling in vertebrates". BioEssays. 29 (2): 120–132. doi:10.1002/bies

RHOQ (1,273 words) [view diff] no match in snippet view article find links to article

PMID 11162552. Joberty G, Petersen C, Gao L, Macara I G (August 2000). "The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42". Nat

Jennifer Lippincott-Schwartz (2,471 words) [view diff] exact match in snippet view article find links to article

and cytoskeleton interaction, organelle assembly and disassembly, and cell polarity generation. There are also projects analyzing the dynamics of proteins

Α-Catenin (2,888 words) [view diff] exact match in snippet view article find links to article

mechanisms by which RhoGEF on endosomes interact with α-catenin to establish cell polarity and migration have been elucidate via biosensors and depletion assays

Prickle (81 words) [view diff] exact match in snippet view article find links to article

needle-like structures Prickle cell of the skin Prickle (protein), a planar cell polarity protein The collective noun for a pack of porcupines Prickle (Gumby

Glypican 6 (426 words) [view diff] exact match in snippet view article find links to article

binding coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway protein binding Cellular component Golgi lumen nucleus integral

PARVB (725 words) [view diff] exact match in snippet view article find links to article

assembly establishment or maintenance of cell polarity regulating cell shape establishment or maintenance of cell polarity substrate adhesion-dependent cell

Convergent extension (800 words) [view diff] exact match in snippet view article find links to article

convergent extension and recently the planar cell polarity (PCP) pathway was implicated in regulating the cell polarity of the factors involved in convergent

LIN7A (937 words) [view diff] exact match in snippet view article find links to article

An obligate heterodimerization involved in assembly of signaling and cell polarity complexes". J. Biol. Chem. 277 (38): 34902–8. doi:10.1074/jbc.M205856200

DLG1 (1,966 words) [view diff] exact match in snippet view article find links to article

Humbert P, Russell S, Richardson H (Jun 2003). "Dlg, Scribble and Lgl in cell polarity, cell proliferation and cancer". BioEssays. 25 (6): 542–53. doi:10.1002/bies

DVL3 (890 words) [view diff] exact match in snippet view article find links to article

canonical Wnt signaling pathway Wnt signaling pathway, planar cell polarity pathway planar cell polarity pathway involved in neural tube closure positive regulation

Colorectal adenoma (517 words) [view diff] exact match in snippet view article find links to article

dysplasia in a tubulovillous adenoma, in this case seen mainly as loss of cell polarity, as cells become more plump and haphazard than the elongated and parallel

Neuroepithelial cell (2,122 words) [view diff] exact match in snippet view article find links to article

the apical plasma membrane as well as tight junctions to maintain the cell polarity. Integrin alpha 6 anchors the neuroepithelial cells to the basal lamina

FSCN1 (1,019 words) [view diff] exact match in snippet view article find links to article

process regulation of microvillus assembly establishment of apical/basal cell polarity regulation of actin cytoskeleton organization actin filament organization

PSMA8 (121 words) [view diff] exact match in snippet view article find links to article

regulation of canonical Wnt signaling pathway Wnt signaling pathway, planar cell polarity pathway proteasome-mediated ubiquitin-dependent protein catabolic process

LIN7B (817 words) [view diff] exact match in snippet view article find links to article

Iwamoto I, Morishita R, Asano T, Nagata K (2007). "Identification of a cell polarity-related protein, Lin-7B, as a binding partner for a Rho effector, Rhotekin

Glypican 4 (584 words) [view diff] exact match in snippet view article find links to article

binding coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway Cellular component membrane plasma membrane integral component

ROCK2 (213 words) [view diff] exact match in snippet view article find links to article

I-kappaB kinase/NF-kappaB signaling regulation of establishment of cell polarity cortical actin cytoskeleton organization regulation of establishment

Daniel Louvard (1,566 words) [view diff] exact match in snippet view article find links to article

epithelial cells. He continues his research on the molecular basis of cell polarity, cell motility and cell plasticity. More recently, he has developed

SDCCAG8 (480 words) [view diff] exact match in snippet view article find links to article

cell cycle microtubule organizing center organization establishment of cell polarity tube formation ciliary basal body-plasma membrane docking centrosome

RhoH (1,032 words) [view diff] exact match in snippet view article find links to article

transduction actin filament organization establishment or maintenance of cell polarity Rho protein signal transduction regulation of cell shape actin cytoskeleton

Glycogen synthase kinase-3 beta (1,819 words) [view diff] exact match in snippet view article find links to article

positive regulation of gene expression establishment of cell polarity maintenance of cell polarity regulation of axon extension negative regulation of phosphoprotein

Erbin (protein) (1,517 words) [view diff] exact match in snippet view article

2003). "Identification of three novel Smad binding proteins involved in cell polarity". FEBS Lett. 539 (1–3): 167–73. doi:10.1016/s0014-5793(03)00155-8. PMID 12650946

Nephronophthisis (865 words) [view diff] exact match in snippet view article find links to article

gene mutations cause defects in signaling resulting in flaws of planar cell polarity. The ciliary theory indicates that multiple organs are involved in NPHP

Serous gland (1,028 words) [view diff] exact match in snippet view article find links to article

organization in the developing pancreas: a perspective on the role of cell polarity in coordinating tissue growth and differentiation". Journal of Cell

BRSK2 (493 words) [view diff] exact match in snippet view article find links to article

transport, ER to cytosol exocytosis apoptotic process establishment of cell polarity regulation of insulin secretion involved in cellular response to glucose

RIPOR2 (546 words) [view diff] exact match in snippet view article find links to article

regulation of myoblast fusion negative regulation of establishment of T cell polarity negative regulation of T cell migration negative regulation of T cell

Frizzled-6 (746 words) [view diff] exact match in snippet view article find links to article

activation multicellular organism development Wnt signaling pathway, planar cell polarity pathway embryonic nail plate morphogenesis cell surface receptor signaling

CELSR2 (493 words) [view diff] exact match in snippet view article find links to article

development regulation of cell-cell adhesion Wnt signaling pathway, planar cell polarity pathway G protein-coupled receptor signaling pathway signal transduction

CLASP1 (1,134 words) [view diff] exact match in snippet view article find links to article

microtubule kinetochore Biological process establishment of epithelial cell polarity vesicle targeting Golgi organization mitotic spindle organization regulation

MAPRE1 (1,242 words) [view diff] exact match in snippet view article find links to article

Bierer BE (May 2000). "EB1 proteins regulate microtubule dynamics, cell polarity, and chromosome stability". The Journal of Cell Biology. 149 (4): 761–6

MKS1 (760 words) [view diff] exact match in snippet view article find links to article

stereocilium organization regulation of Wnt signaling pathway, planar cell polarity pathway regulation of canonical Wnt signaling pathway motile cilium

NPHP4 (658 words) [view diff] exact match in snippet view article find links to article

epithelial cell-cell junctions, interaction with filamins, and establishing cell polarity". J. Biol. Chem. 277 (32): 29028–35. doi:10.1074/jbc.M111697200. PMID 12006559

Cell fate determination (2,966 words) [view diff] exact match in snippet view article find links to article

cell polarity pathways. Semin Cell Dev Biol 2009, 20:972-977. Segalen, M.; Bellaïche, Y. (2009). "Cell division orientation and planar cell polarity pathways"

MARK1 (957 words) [view diff] exact match in snippet view article find links to article

protein phosphorylation cytoskeleton organization establishment of cell polarity microtubule cytoskeleton organization regulation of neuron projection

Protein kinase C zeta type (2,686 words) [view diff] exact match in snippet view article find links to article

Sumimoto H (2001). "Human homologues of the Caenorhabditis elegans cell polarity protein PAR6 as an adaptor that links the small GTPases Rac and Cdc42

DVL2 (1,105 words) [view diff] exact match in snippet view article find links to article

JUN kinase activity planar cell polarity pathway involved in neural tube closure Wnt signaling pathway, planar cell polarity pathway beta-catenin destruction

SMURF1 (1,918 words) [view diff] exact match in snippet view article find links to article

Alexandrova E, Thomsen GH, Wrana JL (December 2003). "Regulation of cell polarity and protrusion formation by targeting RhoA for degradation". Science

AP2S1 (783 words) [view diff] exact match in snippet view article find links to article

transport microtubule-based movement Wnt signaling pathway, planar cell polarity pathway membrane organization low-density lipoprotein particle receptor

SFRP2 (1,128 words) [view diff] exact match in snippet view article find links to article

peptidyl-serine phosphorylation positive regulation of angiogenesis planar cell polarity pathway involved in neural tube closure negative regulation of BMP signaling

Frizzled-7 (795 words) [view diff] exact match in snippet view article find links to article

mesenchymal to epithelial transition Wnt signaling pathway, planar cell polarity pathway negative regulation of cardiac muscle cell differentiation regulation

Frizzled-5 (827 words) [view diff] exact match in snippet view article find links to article

signaling pathway, calcium modulating pathway Wnt signaling pathway, planar cell polarity pathway beta-catenin destruction complex disassembly Sources:Amigo /

CD3G (1,024 words) [view diff] exact match in snippet view article find links to article

Biological process protein transport establishment or maintenance of cell polarity cell surface receptor signaling pathway T cell receptor signaling pathway

SNX27 (490 words) [view diff] exact match in snippet view article find links to article

endosome cytosol Biological process establishment of natural killer cell polarity endosome to lysosome transport endosomal transport protein transport

MYO5B (982 words) [view diff] exact match in snippet view article find links to article

mutations cause microvillus inclusion disease and disrupt epithelial cell polarity". Nature Genetics. 40 (10): 1163–5. doi:10.1038/ng.225. PMID 18724368

MARK3 (1,217 words) [view diff] exact match in snippet view article find links to article

phosphorylation microtubule cytoskeleton organization establishment of cell polarity negative regulation of hippo signaling peptidyl-serine phosphorylation

Microvillous inclusion disease (841 words) [view diff] exact match in snippet view article find links to article

mutations cause microvillus inclusion disease and disrupt epithelial cell polarity". Nat Genet. 40 (10): 1163–5. doi:10.1038/ng.225. PMID 18724368. S2CID 205345488

Wee1-like protein kinase (1,028 words) [view diff] exact match in snippet view article find links to article

process cell cycle neuron projection morphogenesis establishment of cell polarity cell division G2/M transition of mitotic cell cycle microtubule cytoskeleton

PTPRB (1,030 words) [view diff] exact match in snippet view article find links to article

"VE-PTP regulates VEGFR2 activity in stalk cells to establish endothelial cell polarity and lumen formation". Nature Communications. 4 (1): 1672. Bibcode:2013NatCo

ARF6 (1,429 words) [view diff] exact match in snippet view article find links to article

glutamatergic synapse Biological process establishment of epithelial cell polarity cell differentiation regulation of filopodium assembly positive regulation

Kathryn Ayscough (661 words) [view diff] exact match in snippet view article find links to article

budding yeast and roles for actin in establishment and maintenance of cell polarity revealed using the actin inhibitor latrunculin-A Latrunculin alters

CD43 (1,283 words) [view diff] exact match in snippet view article find links to article

thymic T cell selection chemotaxis establishment or maintenance of cell polarity cellular defense response cell surface receptor signaling pathway negative

Tight junction protein ZO-1 (2,034 words) [view diff] exact match in snippet view article find links to article

JAM-2 and JAM-3 associate with the cell polarity protein PAR-3: a possible role for JAMs in endothelial cell polarity". Journal of Cell Science. 116 (Pt

Exocyst (551 words) [view diff] exact match in snippet view article find links to article

exocyst also interacts with Rho GTPases responsible for controlling cell polarity and the activity of the cytoskeleton. Hints of a multi-subunit complex

Blastomere (1,740 words) [view diff] no match in snippet view article find links to article

at that time. The other, more widely accepted model is known as the "cell-polarity model". This model states that the orientation of the cleavage plane

PSME4 (828 words) [view diff] exact match in snippet view article find links to article

ubiquitin-dependent protein catabolic process Wnt signaling pathway, planar cell polarity pathway proteasomal ubiquitin-independent protein catabolic process

PRICKLE4 (325 words) [view diff] exact match in snippet view article find links to article

Identifiers Aliases PRICKLE4, C6orf49, OBTP, OEBT, TOMM6, prickle planar cell polarity protein 4 External IDs OMIM: 611389; MGI: 2685785; HomoloGene: 22752;

Xin Lu (997 words) [view diff] exact match in snippet view article find links to article

"STAT1-induced ASPP2 transcription identifies a link between neuroinflammation, cell polarity, and tumor suppression". Proceedings of the National Academy of Sciences

AP2A2 (1,092 words) [view diff] exact match in snippet view article find links to article

transport microtubule-based movement Wnt signaling pathway, planar cell polarity pathway neutrophil degranulation membrane organization low-density lipoprotein

Protein c-Fos (3,991 words) [view diff] exact match in snippet view article find links to article

important factor for cancer development. It can also induce a loss of cell polarity and epithelial-mesenchymal transition, leading to invasive and metastatic

Flamingo (disambiguation) (586 words) [view diff] exact match in snippet view article

Glass Sport Motors Flamingo (protein), a protein involved in planar cell polarity and dendrite structure Flamingo flower, common name for flowers in the

HES5 (754 words) [view diff] exact match in snippet view article find links to article

auditory receptor cell fate determination establishment of epithelial cell polarity cell differentiation negative regulation of astrocyte differentiation

Angiomotin (2,243 words) [view diff] exact match in snippet view article find links to article

Ser-176 inhibits cell migration and angiogenesis. In the outer cells, the cell polarity sequesters AMOT from basolateral adherens junctions to apical domains

Arp2/3 complex (4,153 words) [view diff] exact match in snippet view article find links to article

complex has also been shown to be involved in the establishment of cell polarity and the migration of fibroblast monolayers in a wound-healing model

BCAS3 (766 words) [view diff] exact match in snippet view article find links to article

of GTPase activity Golgi organization regulation of establishment of cell polarity tube formation regulation of transcription, DNA-templated positive regulation

CLIC4 (1,251 words) [view diff] exact match in snippet view article find links to article

migration fertilization establishment or maintenance of apical/basal cell polarity chloride transport branching morphogenesis of an epithelial tube retina

CAP2 (320 words) [view diff] exact match in snippet view article find links to article

postsynaptic density Biological process establishment or maintenance of cell polarity cytoskeleton organization signal transduction activation of adenylate

FLNB (1,335 words) [view diff] exact match in snippet view article find links to article

epithelial cell-cell junctions, interaction with filamins, and establishing cell polarity". J. Biol. Chem. 277 (32): 29028–35. doi:10.1074/jbc.M111697200. PMID 12006559

RICTOR (2,139 words) [view diff] exact match in snippet view article find links to article

phosphorylation regulation of protein kinase B signaling establishment of cell polarity regulation of inflammatory response positive regulation of peptidyl-tyrosine

FSCN3 (362 words) [view diff] exact match in snippet view article find links to article

anatomical structure morphogenesis establishment or maintenance of cell polarity actin filament bundle assembly cell migration Sources:Amigo / QuickGO

Frizzled-4 (1,162 words) [view diff] exact match in snippet view article find links to article

signaling pathway, calcium modulating pathway Wnt signaling pathway, planar cell polarity pathway membrane organization non-canonical Wnt signaling pathway positive

AP2B1 (1,298 words) [view diff] exact match in snippet view article find links to article

transport microtubule-based movement Wnt signaling pathway, planar cell polarity pathway membrane organization neurotransmitter receptor internalization

RHOBTB3 (416 words) [view diff] exact match in snippet view article find links to article

transport actin filament organization establishment or maintenance of cell polarity Rho protein signal transduction regulation of cell shape actin cytoskeleton

Nectin-3 (1,766 words) [view diff] exact match in snippet view article find links to article

Takeuchi M, Monden M, Takai Y (February 2003). "Direct binding of cell polarity protein PAR-3 to cell-cell adhesion molecule nectin at neuroepithelial

FERMT1 (852 words) [view diff] exact match in snippet view article find links to article

proliferation cell adhesion keratinocyte migration establishment of epithelial cell polarity positive regulation of cell-matrix adhesion negative regulation of gene

Polycystin 1 (839 words) [view diff] exact match in snippet view article find links to article

export from nucleus detection of mechanical stimulus establishment of cell polarity spinal cord development metanephric collecting duct development liver

AP2M1 (1,313 words) [view diff] exact match in snippet view article find links to article

transport intracellular protein transport Wnt signaling pathway, planar cell polarity pathway microtubule-based movement membrane organization low-density

Poliovirus receptor-related 1 (1,379 words) [view diff] exact match in snippet view article find links to article

Morimoto K, Takeuchi M, Monden M, Takai Y (2003). "Direct binding of cell polarity protein PAR-3 to cell–cell adhesion molecule nectin at neuroepithelial

Gary Struhl (1,548 words) [view diff] exact match in snippet view article find links to article

published a paper relating to frizzled function that analyzed the planar cell polarity of epithelial cells. In this paper, it was concluded that each of the

Ubiquitin A-52 residue ribosomal protein fusion product 1 (825 words) [view diff] exact match in snippet view article find links to article

signal transduction by p53 class mediator Wnt signaling pathway, planar cell polarity pathway nucleotide-excision repair, DNA incision, 5'-to lesion protein

FLNA (1,270 words) [view diff] exact match in snippet view article find links to article

epithelial cell-cell junctions, interaction with filamins, and establishing cell polarity". Journal of Biological Chemistry. 277 (32): 29028–29035. doi:10.1074/jbc

Tight junction (2,079 words) [view diff] exact match in snippet view article find links to article

function of tight junctions and is also involved in helping to maintain cell polarity. As part of the immunoglobin superfamily, JAMs have important roles

Adaptor-related protein complex 2, alpha 1 (1,005 words) [view diff] exact match in snippet view article find links to article

endocytosis microtubule-based movement Wnt signaling pathway, planar cell polarity pathway negative regulation of hyaluronan biosynthetic process membrane

Syntaxin 3 (1,462 words) [view diff] exact match in snippet view article find links to article

separate clusters on the plasma membrane before the establishment of cell polarity". Mol. Biol. Cell. 17 (2): 977–89. doi:10.1091/mbc.E05-05-0462. PMC 1356605

Inner cell mass (1,750 words) [view diff] exact match in snippet view article find links to article

Development 135, 953-962 (2008) Jedrusik, Agnieszka, et al. Role of Cdx2 and cell polarity in cell allocation and specification of trophectoderm and inner cell

CLTC (1,087 words) [view diff] exact match in snippet view article find links to article

process intracellular protein transport Wnt signaling pathway, planar cell polarity pathway regulation of mitotic spindle organization autophagy microtubule-based

Cofilin 1 (1,199 words) [view diff] exact match in snippet view article find links to article

protein phosphorylation actin filament organization establishment of cell polarity actin filament fragmentation positive regulation of actin filament depolymerization

RIKEN Quantitative Biology Center (458 words) [view diff] case mismatch in snippet view article find links to article

Research Core The Cell Dynamics Research Core houses the Laboratory for Cell Polarity Regulation, led by Yasushi Okada. Okada reported the first visualization

Hypoblast (1,618 words) [view diff] exact match in snippet view article find links to article

regulated by FGFs from the hypoblast, which activates the Wnt planar cell polarity pathway in the epiblast. The Wnt pathway, in turn, is activated by FGFs

VE-cadherin (2,113 words) [view diff] exact match in snippet view article find links to article

factor beta receptor signaling pathway regulation of establishment of cell polarity negative regulation of cell population proliferation homophilic cell

FMNL2 (434 words) [view diff] exact match in snippet view article find links to article

Formin-related proteins have been implicated in morphogenesis, cytokinesis, and cell polarity. FMNL2 expression is considerably higher in colorectal cancer tumors

PARVG (509 words) [view diff] exact match in snippet view article find links to article

cell-matrix adhesion cell adhesion establishment or maintenance of cell polarity cell projection assembly substrate adhesion-dependent cell spreading

PSME3 (1,147 words) [view diff] exact match in snippet view article find links to article

protein catabolic process apoptotic process Wnt signaling pathway, planar cell polarity pathway negative regulation of G2/M transition of mitotic cell cycle

PSME2 (1,178 words) [view diff] exact match in snippet view article find links to article

ubiquitin-dependent protein catabolic process Wnt signaling pathway, planar cell polarity pathway negative regulation of G2/M transition of mitotic cell cycle

AMOTL2 (490 words) [view diff] exact match in snippet view article find links to article

Biological process Wnt signaling pathway hippo signaling establishment of cell polarity involved in ameboidal cell migration actin cytoskeleton organization

STX2 (1,272 words) [view diff] exact match in snippet view article find links to article

separate clusters on the plasma membrane before the establishment of cell polarity". Molecular Biology of the Cell. 17 (2): 977–89. doi:10.1091/mbc.E05-05-0462

Dystonin (1,478 words) [view diff] exact match in snippet view article find links to article

cytoskeleton organization integrin-mediated signaling pathway maintenance of cell polarity microtubule cytoskeleton organization retrograde axonal transport cytoskeleton

LIN7C (697 words) [view diff] exact match in snippet view article find links to article

LIN7C, LIN-7-C, LIN-7C, MALS-3, MALS3, VELI3, lin-7 homolog C, crumbs cell polarity complex component External IDs OMIM: 612332; MGI: 1330839; HomoloGene:

PSME1 (1,255 words) [view diff] exact match in snippet view article find links to article

ubiquitin-dependent protein catabolic process Wnt signaling pathway, planar cell polarity pathway negative regulation of G2/M transition of mitotic cell cycle

FERM Domain Containing 4A (81 words) [view diff] exact match in snippet view article find links to article

junction cell junction Biological process establishment of epithelial cell polarity negative regulation of protein secretion positive regulation of protein

FERM Domain Containing 4A (81 words) [view diff] exact match in snippet view article find links to article

junction cell junction Biological process establishment of epithelial cell polarity negative regulation of protein secretion positive regulation of protein

PSMF1 (1,254 words) [view diff] exact match in snippet view article find links to article

ubiquitin-dependent protein catabolic process Wnt signaling pathway, planar cell polarity pathway negative regulation of endopeptidase activity negative regulation

NDR kinase (422 words) [view diff] exact match in snippet view article find links to article

the study of cell morphogenesis, the Ndr kinase Orb6 has a role in cell polarity and morphogenesis control in part by the regulation of small Rho-type

Sodium–hydrogen antiporter 1 (1,439 words) [view diff] exact match in snippet view article find links to article

action potential cellular response to mechanical stimulus maintenance of cell polarity cellular response to hypoxia positive regulation of mitochondrial membrane

PARVA (680 words) [view diff] exact match in snippet view article find links to article

outflow tract septum morphogenesis establishment or maintenance of cell polarity chemotaxis actin-mediated cell contraction cell adhesion cell projection

STK25 (665 words) [view diff] exact match in snippet view article find links to article

Golgi localization Golgi reassembly establishment or maintenance of cell polarity protein phosphorylation Golgi localization protein autophosphorylation

SEMA6A (580 words) [view diff] exact match in snippet view article find links to article

Katoh M (2007). "Comparative integromics on non-canonical WNT or planar cell polarity signaling molecules: transcriptional mechanism of PTK7 in colorectal

R-spondin 3 (483 words) [view diff] exact match in snippet view article find links to article

signaling pathway positive regulation of Wnt signaling pathway, planar cell polarity pathway Wnt signaling pathway branching involved in labyrinthine layer

WNT7A (1,066 words) [view diff] exact match in snippet view article find links to article

muscle regeneration angiogenesis oviduct development establishment of cell polarity central nervous system vasculogenesis positive regulation of excitatory

Kate Storey (650 words) [view diff] exact match in snippet view article find links to article

9:e1003614. Das, R.M. and Storey, K.G. (2014) Apical abscission alters cell polarity and dismantles the primary cilium during neurogenesis. Science 343,

CAP1 (857 words) [view diff] exact match in snippet view article find links to article

azurophil granule lumen Biological process establishment or maintenance of cell polarity ameboidal-type cell migration receptor-mediated endocytosis actin cytoskeleton

Prokaryotic cytoskeleton (2,466 words) [view diff] exact match in snippet view article find links to article

Z, Dye N, Shapiro L (June 2004). "An actin-like gene can determine cell polarity in bacteria". Proceedings of the National Academy of Sciences of the

Myosin light-chain kinase (1,731 words) [view diff] exact match in snippet view article find links to article

(September 2010). "Rho-kinase/ROCK: A key regulator of the cytoskeleton and cell polarity". Cytoskeleton. 67 (9): 545–54. doi:10.1002/cm.20472. PMC 3038199. PMID 20803696

40S ribosomal protein S27a (929 words) [view diff] exact match in snippet view article find links to article

rRNA processing ERBB2 signaling pathway Wnt signaling pathway, planar cell polarity pathway nucleotide-excision repair, preincision complex assembly proteasome-mediated

CLASP2 (691 words) [view diff] exact match in snippet view article find links to article

migration exit from mitosis cell division establishment or maintenance of cell polarity positive regulation of extracellular matrix disassembly positive regulation

Ensconsin (894 words) [view diff] exact match in snippet view article find links to article

process response to osmotic stress establishment or maintenance of cell polarity protein localization to plasma membrane microtubule cytoskeleton organization

KIF13B (132 words) [view diff] exact match in snippet view article find links to article

"Transport of PIP3 by GAKIN, a kinesin-3 family protein, regulates neuronal cell polarity". J. Cell Biol. 174 (3): 425–36. doi:10.1083/jcb.200604031. PMC 2064238

MAP1B (1,060 words) [view diff] exact match in snippet view article find links to article

mitochondrion transport along microtubule establishment of monopolar cell polarity cellular process or phenomenon microtubule cytoskeleton organization

Chromosome 6 (2,403 words) [view diff] exact match in snippet view article find links to article

disease 1 (autosomal recessive) (6p21.2-p12) PRICKLE4: prickle planar cell polarity protein 4 (6p21.1) PRSS16: protease, serine 16 (6p22.1) PSMB8-AS1: PSMB8

Richard Lounsbery Award (1,601 words) [view diff] exact match in snippet view article find links to article

timing, nucleus breakdown and reformation, and microtubule control of cell polarity and mitosis. 1991 Harold Weintraub, for elucidating a molecular mechanism

FOXJ1 (1,996 words) [view diff] exact match in snippet view article find links to article

differentiation in thymus cilium assembly establishment of apical/basal cell polarity activation of GTPase activity negative regulation of B cell activation

Transforming protein RhoA (5,373 words) [view diff] exact match in snippet view article find links to article

concerted action of ROCK and Dia is essential for the regulation of cell polarity and organization of microtubules. RhoA also regulates the integrity

CCL19 (1,396 words) [view diff] exact match in snippet view article find links to article

response positive regulation of ERK1 and ERK2 cascade establishment of T cell polarity positive regulation of glycoprotein biosynthetic process cellular response

MLLT3 (683 words) [view diff] exact match in snippet view article find links to article

Biological process positive regulation of Wnt signaling pathway, planar cell polarity pathway regulation of transcription, DNA-templated negative regulation

PAX8 (2,329 words) [view diff] exact match in snippet view article find links to article

proliferation and differentiation, signal transduction, apoptosis, cell polarity and transport, cell motility and adhesion. Mutations in this gene have

Dedicator of cytokinesis protein 8 (1,254 words) [view diff] exact match in snippet view article find links to article

regulation of GTPase activity positive regulation of establishment of T cell polarity cellular response to chemokine positive regulation of T cell migration

FLNC (gene) (2,371 words) [view diff] exact match in snippet view article

epithelial cell-cell junctions, interaction with filamins, and establishing cell polarity". The Journal of Biological Chemistry. 277 (32): 29028–35. doi:10.1074/jbc

FSCN2 (588 words) [view diff] exact match in snippet view article find links to article

actin filament bundle assembly eye photoreceptor cell development establishment or maintenance of cell polarity cell migration Sources:Amigo / QuickGO

EPH receptor B1 (1,109 words) [view diff] exact match in snippet view article find links to article

activation cranial nerve development neurogenesis establishment of cell polarity detection of temperature stimulus involved in sensory perception of

Chromosome 1 (3,304 words) [view diff] exact match in snippet view article find links to article

recessive, mild) USF1 (1q23) VANGL2: encoding protein VANGL planar cell polarity protein 2 VPS45: Vacuolar protein sorting-associated protein 45 VPS72:

NEK3 (585 words) [view diff] exact match in snippet view article find links to article

projection axon nucleus cytoplasm Biological process establishment of cell polarity cell cycle phosphorylation cell division neuron projection morphogenesis

PTK2B (1,887 words) [view diff] exact match in snippet view article find links to article

of nitric oxide biosynthetic process regulation of establishment of cell polarity response to hydrogen peroxide regulation of macrophage chemotaxis positive

STX4 (2,104 words) [view diff] exact match in snippet view article find links to article

separate clusters on the plasma membrane before the establishment of cell polarity". Molecular Biology of the Cell. 17 (2): 977–89. doi:10.1091/mbc.E05-05-0462

RAC1 (3,077 words) [view diff] exact match in snippet view article find links to article

H (February 2001). "Human homologues of the Caenorhabditis elegans cell polarity protein PAR6 as an adaptor that links the small GTPases Rac and Cdc42

Otolithic membrane (2,636 words) [view diff] exact match in snippet view article find links to article

of other hair cells in these organs. Ultimately, variations in hair cell polarity within the otolith organs produce patterns of vestibular nerve fiber

RhoG (2,844 words) [view diff] exact match in snippet view article find links to article

pathway actin filament organization establishment or maintenance of cell polarity regulation of cell shape regulation of actin cytoskeleton organization

Pollen tube (6,442 words) [view diff] exact match in snippet view article find links to article

PMID 20805480. Fu, Ying; Yang, Zhenbiao (2001). "Rop GTPase: a master switch of cell polarity development in plants". Trends in Plant Science. 6 (12): 545–547. doi:10

ANKRD15 (533 words) [view diff] exact match in snippet view article find links to article

substrate adhesion-dependent cell spreading regulation of establishment of cell polarity positive regulation of canonical Wnt signaling pathway regulation of

SFRP5 (527 words) [view diff] exact match in snippet view article find links to article

multicellular organism development establishment or maintenance of cell polarity negative regulation of Wnt signaling pathway involved in digestive tract

PAK1 (5,202 words) [view diff] exact match in snippet view article find links to article

(May 2012). "STE20-related kinase adaptor protein α (STRADα) regulates cell polarity and invasion through PAK1 signaling in LKB1-null cells". The Journal

B cell (3,750 words) [view diff] exact match in snippet view article find links to article

"How B cells capture, process and present antigens: a crucial role for cell polarity". Nature Reviews. Immunology. 13 (7): 475–486. doi:10.1038/nri3469.

CCL21 (1,981 words) [view diff] exact match in snippet view article find links to article

cellular response to interleukin-1 immune response establishment of T cell polarity positive regulation of ERK1 and ERK2 cascade positive regulation of

SMEK2 (740 words) [view diff] exact match in snippet view article find links to article

2005). "Loss of SMEK, a novel, conserved protein, suppresses MEK1 null cell polarity, chemotaxis, and gene expression defects". Molecular and Cellular Biology

Claudin 25 (201 words) [view diff] exact match in snippet view article find links to article

endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. [provided by RefSeq, Jun 2010]. GRCh38: Ensembl

Epsin (1,546 words) [view diff] exact match in snippet view article find links to article

activity which provides an alternative mechanism for epsin's role in cell polarity and migration. In addition, Epsin is thought to play a role in the Notch

RNF41 (647 words) [view diff] exact match in snippet view article find links to article

regulation of myeloid cell differentiation regulation of establishment of cell polarity negative regulation of cell population proliferation protein autoubiquitination

ARPC5 (669 words) [view diff] exact match in snippet view article find links to article

lamellipodium organization smooth muscle cell migration maintenance of cell polarity neutrophil degranulation membrane organization microtubule organizing

MAPRE2 (944 words) [view diff] exact match in snippet view article find links to article

JS, Bierer BE (2000). "EB1 proteins regulate microtubule dynamics, cell polarity, and chromosome stability". J. Cell Biol. 149 (4): 761–6. doi:10.1083/jcb

ARPC5 (669 words) [view diff] exact match in snippet view article find links to article

lamellipodium organization smooth muscle cell migration maintenance of cell polarity neutrophil degranulation membrane organization microtubule organizing

CAB39 (626 words) [view diff] exact match in snippet view article find links to article

Smit L, Clevers H (2004). "LKB1 tumor suppressor protein: PARtaker in cell polarity". Trends Cell Biol. 14 (6): 312–9. doi:10.1016/j.tcb.2004.04.001. PMID 15183188

BRSK1 (601 words) [view diff] exact match in snippet view article find links to article

response to DNA damage stimulus centrosome duplication establishment of cell polarity neurotransmitter secretion axonogenesis neuron differentiation protein

Statocyte (527 words) [view diff] exact match in snippet view article find links to article

Toyota, Masatsugu; Higaki, Takumi; Morita, Miyo Terao (2023-08-10). "Cell polarity linked to gravity sensing is generated by LZY translocation from statoliths

Koller's sickle (1,429 words) [view diff] exact match in snippet view article find links to article

the center of the epiblast following the activation of the Wnt planar cell polarity pathway by fibroblast growth factors made by the hypoblast. There is

Receptor for activated C kinase 1 (2,598 words) [view diff] exact match in snippet view article find links to article

cycle regulation of growth viral process regulation of establishment of cell polarity activation of cysteine-type endopeptidase activity involved in apoptotic

DLG5 (965 words) [view diff] exact match in snippet view article find links to article

population proliferation epithelial to mesenchymal transition maintenance of cell polarity negative regulation of cell migration negative regulation of hippo signaling

MYH10 (2,425 words) [view diff] exact match in snippet view article find links to article

play a role in cell-cell and cell-matrix adhesion, cell migration, cell polarity, and embryonic stem cell apoptosis. Insights into the function of NM-IIB

Proto-oncogene Wnt-1 (1,008 words) [view diff] exact match in snippet view article find links to article

midbrain dopaminergic neuron differentiation Wnt signaling pathway, planar cell polarity pathway beta-catenin destruction complex disassembly negative regulation

MED12 (1,685 words) [view diff] exact match in snippet view article find links to article

regulation of transcription, DNA-templated Wnt signaling pathway, planar cell polarity pathway heart development neural tube closure embryonic brain development

RAP1B (939 words) [view diff] exact match in snippet view article find links to article

assembly Rap protein signal transduction regulation of establishment of cell polarity cellular response to cAMP signal transduction neutrophil degranulation

Cadherin (3,588 words) [view diff] exact match in snippet view article find links to article

PMC 6859941. PMID 31742239. Butler MT, Wallingford JB (June 2017). "Planar cell polarity in development and disease". Nature Reviews Molecular Cell Biology.

Gelsolin (1,645 words) [view diff] exact match in snippet view article find links to article

apoptotic process striated muscle atrophy regulation of establishment of T cell polarity extracellular matrix disassembly positive regulation of cysteine-type

RAB11FIP2 (1,027 words) [view diff] exact match in snippet view article find links to article

transport regulated exocytosis renal water homeostasis establishment of cell polarity insulin secretion involved in cellular response to glucose stimulus

LOXL2 (1,205 words) [view diff] exact match in snippet view article find links to article

J, Cano A (2011). "Lysyl oxidase-like 2 (LOXL2), a new regulator of cell polarity required for metastatic dissemination of basal-like breast carcinomas"

CYP26B1 (1,262 words) [view diff] exact match in snippet view article find links to article

morphogenesis vitamin metabolic process spermatogenesis establishment of T cell polarity cornification cell fate determination inflammatory response regulation

Torsin A (910 words) [view diff] exact match in snippet view article find links to article

Ferrari Toninelli G, Spano P, Memo M (2003). "TorsinA, microtubules and cell polarity". Funct. Neurol. 18 (1): 7–10. PMID 12760408. Rothwell JC, Edwards M

Polycystic kidney disease (2,815 words) [view diff] exact match in snippet view article find links to article

calcium, Wnt/β-catenin, cyclic adenosine monophosphate (cAMP), or planar cell polarity (PCP). Function of the primary cilium is impaired, resulting in disruption

Shootin 1 (217 words) [view diff] exact match in snippet view article find links to article

morphogenesis endoplasmic reticulum polarization regulation of establishment of cell polarity regulation of neuron migration positive regulation of neuron migration

GBF1 (881 words) [view diff] exact match in snippet view article find links to article

organization post-Golgi vesicle-mediated transport establishment of monopolar cell polarity protein localization to endoplasmic reticulum exit site regulation of

Profilin 1 (2,606 words) [view diff] exact match in snippet view article find links to article

assembly actin cytoskeleton organization Wnt signaling pathway, planar cell polarity pathway response to organic substance positive regulation of transcription

Dedicator of cytokinesis protein 2 (1,587 words) [view diff] exact match in snippet view article find links to article

immune response positive thymic T cell selection establishment of T cell polarity immunological synapse formation actin cytoskeleton organization T cell

C-C chemokine receptor type 7 (2,527 words) [view diff] exact match in snippet view article find links to article

regulation of humoral immune response immune response establishment of T cell polarity positive regulation of ERK1 and ERK2 cascade positive regulation of

Ezrin (1,381 words) [view diff] exact match in snippet view article find links to article

intestinal D-glucose absorption establishment or maintenance of apical/basal cell polarity regulation of NIK/NF-kappaB signaling epithelial cell differentiation

Cdc42 binding protein kinase beta (353 words) [view diff] exact match in snippet view article find links to article

phosphorylation actomyosin structure organization establishment or maintenance of cell polarity protein phosphorylation cytoskeleton organization cell migration signal

SHFM1 (840 words) [view diff] exact match in snippet view article find links to article

signaling pathway transmembrane transport Wnt signaling pathway, planar cell polarity pathway regulation of transcription from RNA polymerase II promoter

Collecting duct system (2,212 words) [view diff] exact match in snippet view article find links to article

collecting duct protein involved in the in vitro plasticity of intercalated cell polarity". The Journal of Clinical Investigation. 98 (10): 2324–31. doi:10.1172/JCI119044

WWC1 (1,113 words) [view diff] exact match in snippet view article find links to article

DNA-templated negative regulation of hippo signaling establishment of cell polarity regulation of hippo signaling negative regulation of organ growth cell

Blastocyst (3,144 words) [view diff] exact match in snippet view article find links to article

is controlled by the combination of morphological cues arising from cell polarity with differential activity of signaling pathways such as Hippo and Notch

Epithelial dysplasia (1,162 words) [view diff] exact match in snippet view article find links to article

reduction of cellular cohesion Cellular pleomorphism Loss of basal cell polarity Koilocytosis Epithelial cell dysplasia is divided into three categories

Ralf Adams (531 words) [view diff] exact match in snippet view article find links to article

that Junctional Adhesion Molecules (JAMs) are critical regulators of cell polarity. After his move to the Max Planck Institute for Molecular Biomedicine

MAGI2 (944 words) [view diff] exact match in snippet view article find links to article

receptor signaling pathway nerve growth factor signaling pathway planar cell polarity pathway involved in axis elongation SMAD protein signal transduction

ARHGEF11 (1,581 words) [view diff] exact match in snippet view article find links to article

regulation of cell growth Rho protein signal transduction establishment of cell polarity positive regulation of apoptotic process regulation of Rho protein signal

Microtubule-associated protein 2 (1,380 words) [view diff] exact match in snippet view article find links to article

neuron development axonogenesis dendrite development establishment of cell polarity regulation of axonogenesis cellular response to organic substance negative

HES1 (2,892 words) [view diff] exact match in snippet view article find links to article

signaling pathway midbrain development establishment of epithelial cell polarity pituitary gland development comma-shaped body morphogenesis somatic

CYTH1 (1,401 words) [view diff] exact match in snippet view article find links to article

protein signal transduction regulation of cell adhesion vesicle-mediated transport establishment of epithelial cell polarity Sources:Amigo / QuickGO

Catenin beta-1 (12,347 words) [view diff] exact match in snippet view article find links to article

(2012). "Chapter 3: Control of cell polarity and asymmetric division in C. elegans". In Yang Y (ed.). Planar Cell Polarity During Development. Current Topics

SMURF2 (1,326 words) [view diff] exact match in snippet view article find links to article

DNA-templated protein polyubiquitination Wnt signaling pathway, planar cell polarity pathway protein deubiquitination ubiquitin-dependent protein catabolic

Margaret Frame (biologist) (894 words) [view diff] exact match in snippet view article

FAK interacts with key regulators of directional migration and cancer cell polarity, and that tumour progression requires FAK in multiple epithelial cancer

PSMD5 (2,420 words) [view diff] exact match in snippet view article find links to article

signaling pathway transmembrane transport Wnt signaling pathway, planar cell polarity pathway regulation of transcription from RNA polymerase II promoter

WIPF1 (1,716 words) [view diff] exact match in snippet view article find links to article

(June 1999). "The human WASP-interacting protein, WIP, activates the cell polarity pathway in yeast". The Journal of Biological Chemistry. 274 (24): 17103–8

FEZ1 (1,052 words) [view diff] exact match in snippet view article find links to article

neuron projection development hippocampus development establishment of cell polarity positive regulation of anterograde axonal transport of mitochondrion

PSMC6 (2,202 words) [view diff] exact match in snippet view article find links to article

proteasomal protein catabolic process Wnt signaling pathway, planar cell polarity pathway proteasome-mediated ubiquitin-dependent protein catabolic process

SNAI1 (1,850 words) [view diff] exact match in snippet view article find links to article

been shown to interact with CTDSPL, CTDSP1 and CTDSP2. Snail1 affects cell polarity by interacting with members of the Crumbs family including CRUMBS3 and

SNAI1 (1,850 words) [view diff] exact match in snippet view article find links to article

been shown to interact with CTDSPL, CTDSP1 and CTDSP2. Snail1 affects cell polarity by interacting with members of the Crumbs family including CRUMBS3 and

PSMD8 (2,284 words) [view diff] exact match in snippet view article find links to article

ubiquitin-dependent protein catabolic process Wnt signaling pathway, planar cell polarity pathway negative regulation of G2/M transition of mitotic cell cycle

SPINT2 (1,145 words) [view diff] exact match in snippet view article find links to article

negative regulation of cell-cell adhesion establishment or maintenance of cell polarity negative regulation of neural precursor cell proliferation neural tube

PSMD6 (2,357 words) [view diff] exact match in snippet view article find links to article

signaling pathway transmembrane transport Wnt signaling pathway, planar cell polarity pathway regulation of transcription from RNA polymerase II promoter

MPDZ (1,136 words) [view diff] exact match in snippet view article find links to article

MPDZ Identifiers Aliases MPDZ, HYC2, MUPP1, multiple PDZ domain crumbs cell polarity complex component External IDs OMIM: 603785; MGI: 1343489; HomoloGene:

ACTR2 (938 words) [view diff] exact match in snippet view article find links to article

towards spindle pole meiotic cytokinesis establishment or maintenance of cell polarity meiosis asymmetric cell division Arp2/3 complex-mediated actin nucleation

Polarized membrane (1,315 words) [view diff] case mismatch in snippet view article find links to article

Benjamin; Lv, Zhiyi; Wu, Yi (2021). "Establishing and Maintaining Cell Polarity". Frontiers in Cell and Developmental Biology. 9. Creative Commons Attribution

Barbara Sloat (236 words) [view diff] exact match in snippet view article find links to article

two additional genes involved in budding and the establishment of cell polarity in the yeast Saccharomyces cerevisiae." The Journal of cell biology

T-cell lymphoma invasion and metastasis-inducing protein 1 (1,315 words) [view diff] exact match in snippet view article find links to article

axonogenesis neuron projection extension Wnt signaling pathway, planar cell polarity pathway regulation of dopaminergic neuron differentiation regulation

Myelination (2,277 words) [view diff] exact match in snippet view article find links to article

(2010). "On the biogenesis of myelin membranes: sorting, trafficking and cell polarity". FEBS Lett. 584 (9): 1760–70. Bibcode:2010FEBSL.584.1760B. doi:10.1016/j

MRC Laboratory of Molecular Biology (3,809 words) [view diff] exact match in snippet view article find links to article

reticulum, Golgi apparatus or the plasma membrane — and the role of this in cell polarity, have been elucidated by Bretscher, Hugh Pelham and Sean Munro. The

CYTH3 (728 words) [view diff] exact match in snippet view article find links to article

protein signal transduction Golgi vesicle transport positive regulation of cell adhesion establishment of epithelial cell polarity Sources:Amigo / QuickGO

DAB2 (1,389 words) [view diff] exact match in snippet view article find links to article

signaling pathway positive regulation of Wnt signaling pathway, planar cell polarity pathway cell population proliferation negative regulation of transcription

Gap junction (10,776 words) [view diff] exact match in snippet view article find links to article

studies suggested that gap junctions were key in the development of cell polarity and the left-right symmetry in animals. While signaling that determines

MPP5 (951 words) [view diff] exact match in snippet view article find links to article

protein-containing complex Biological process establishment of epithelial cell polarity peripheral nervous system myelin maintenance protein localization to

Stomach (5,248 words) [view diff] exact match in snippet view article find links to article

ability and many morphological and functional similarities, such as cell polarity and apical microvilli, similar organ-specific antigens and associated

USP9X (1,863 words) [view diff] exact match in snippet view article find links to article

slower blastomere cleavage rate, impaired cell adhesion and a loss of cell polarity. It has also been implicated that USP9X is likely to influence developmental

Secreted frizzled-related protein 1 (6,321 words) [view diff] exact match in snippet view article find links to article

regulation of osteoclast differentiation Wnt signaling pathway, planar cell polarity pathway neural crest cell fate commitment positive regulation of focal

PSMD11 (2,468 words) [view diff] exact match in snippet view article find links to article

regulation of canonical Wnt signaling pathway Wnt signaling pathway, planar cell polarity pathway proteasome-mediated ubiquitin-dependent protein catabolic process

HDAC6 (1,738 words) [view diff] exact match in snippet view article find links to article

(February 2007). "Ceramide regulates atypical PKCzeta/lambda-mediated cell polarity in primitive ectoderm cells. A novel function of sphingolipids in morphogenesis"

PSMD9 (2,486 words) [view diff] exact match in snippet view article find links to article

signaling pathway transmembrane transport Wnt signaling pathway, planar cell polarity pathway regulation of transcription from RNA polymerase II promoter

PSMD12 (2,490 words) [view diff] exact match in snippet view article find links to article

ubiquitin-dependent protein catabolic process Wnt signaling pathway, planar cell polarity pathway negative regulation of G2/M transition of mitotic cell cycle

Epiboly (1,710 words) [view diff] exact match in snippet view article find links to article

PMID 19609345. Mungo Marsden; Douglas W. DeSimone (2001-09-15). "Regulation of cell polarity, radial intercalation and epiboly in Xenopus: novel roles for integrin

DKK1 (1,886 words) [view diff] exact match in snippet view article find links to article

kinase activity positive regulation of Wnt signaling pathway, planar cell polarity pathway negative regulation of neuron projection development negative

Chudley–Mccullough syndrome (1,346 words) [view diff] exact match in snippet view article find links to article

exome sequencing and homozygosity mapping identify mutation in the cell polarity protein GPSM2 as the cause of nonsyndromic hearing loss DFNB82". American

PSMD3 (2,506 words) [view diff] exact match in snippet view article find links to article

regulation of canonical Wnt signaling pathway Wnt signaling pathway, planar cell polarity pathway proteasome-mediated ubiquitin-dependent protein catabolic process

David D. Sabatini (1,757 words) [view diff] exact match in snippet view article find links to article

now widely used MDCK cell culture system for the study of epithelial cell polarity and together with Enrique Rodriguez-Boulan reported the landmark discovery

PSMD13 (2,664 words) [view diff] exact match in snippet view article find links to article

signaling pathway proteasome assembly Wnt signaling pathway, planar cell polarity pathway proteasome-mediated ubiquitin-dependent protein catabolic process

PSMC3 (2,428 words) [view diff] exact match in snippet view article find links to article

protein catabolic process viral process Wnt signaling pathway, planar cell polarity pathway proteasome-mediated ubiquitin-dependent protein catabolic process

Arrestin beta 2 (1,965 words) [view diff] exact match in snippet view article find links to article

regulation of interleukin-12 production Wnt signaling pathway, planar cell polarity pathway negative regulation of protein phosphorylation G protein-coupled

HT-29 (1,768 words) [view diff] exact match in snippet view article find links to article

(January 1988). "HT-29 cells are an in vitro model for the generation of cell polarity in epithelia during embryonic differentiation". Proceedings of the National

PSMC2 (2,572 words) [view diff] exact match in snippet view article find links to article

ubiquitin-dependent protein catabolic process Wnt signaling pathway, planar cell polarity pathway viral process positive regulation of proteasomal protein catabolic

ACTR3 (1,193 words) [view diff] exact match in snippet view article find links to article

chromosome movement towards spindle pole establishment or maintenance of cell polarity meiotic cytokinesis membrane organization Sources:Amigo / QuickGO

Michael P. Snyder (1,512 words) [view diff] exact match in snippet view article find links to article

Proteomics. His research at Yale included work on chromosome segregation and cell polarity, leading to the identification of a number of related genes. In 2009

KIF20B (482 words) [view diff] exact match in snippet view article find links to article

regulation of neuron migration cell cycle regulation of establishment of cell polarity regulation of mitotic nuclear division Sources:Amigo / QuickGO

Mark Bretscher (2,026 words) [view diff] exact match in snippet view article find links to article

4419. PMC 25767. PMID 10588667. Thompson, CR; Bretscher, MS (2002). "Cell polarity and locomotion, as well as endocytosis, depend on NSF". Development

ABL (gene) (3,504 words) [view diff] exact match in snippet view article

depolarization positive regulation of Wnt signaling pathway, planar cell polarity pathway platelet-derived growth factor receptor signaling pathway regulation

GATA3 (3,723 words) [view diff] exact match in snippet view article find links to article

regulation of cell population proliferation regulation of establishment of cell polarity ureteric bud formation negative regulation of cell cycle thymic T cell

FAT1 (2,068 words) [view diff] exact match in snippet view article find links to article

anatomical structure morphogenesis establishment or maintenance of cell polarity cell adhesion cell migration homophilic cell adhesion via plasma membrane

PSMC5 (2,856 words) [view diff] exact match in snippet view article find links to article

ubiquitin-dependent protein catabolic process Wnt signaling pathway, planar cell polarity pathway positive regulation of proteasomal protein catabolic process

FLOT2 (1,370 words) [view diff] exact match in snippet view article find links to article

membrane Biological process positive regulation of establishment of T cell polarity regulation of toll-like receptor 3 signaling pathway regulation of heterotypic

Sea urchin (8,127 words) [view diff] exact match in snippet view article find links to article

It has been suggested that epithelial polarity together with planar cell polarity might be sufficient to drive gastrulation in sea urchins. An unusual

KRIT1 (1,402 words) [view diff] exact match in snippet view article find links to article

extracellular space Biological process regulation of establishment of cell polarity negative regulation of angiogenesis small GTPase mediated signal transduction

PSMB3 (2,761 words) [view diff] exact match in snippet view article find links to article

canonical Wnt signaling pathway viral process Wnt signaling pathway, planar cell polarity pathway negative regulation of G2/M transition of mitotic cell cycle

Escargot (transcription factor) (2,000 words) [view diff] exact match in snippet view article

induced in the follicle cells in-situ. It was discovered that loss of cell polarity induces heterogenous multilayering. Esg was upregulated in the heterogenous

PSMC4 (2,801 words) [view diff] exact match in snippet view article find links to article

proteasomal protein catabolic process Wnt signaling pathway, planar cell polarity pathway proteasome-mediated ubiquitin-dependent protein catabolic process

Escargot (transcription factor) (2,000 words) [view diff] exact match in snippet view article

induced in the follicle cells in-situ. It was discovered that loss of cell polarity induces heterogenous multilayering. Esg was upregulated in the heterogenous

PSMB3 (2,761 words) [view diff] exact match in snippet view article find links to article

canonical Wnt signaling pathway viral process Wnt signaling pathway, planar cell polarity pathway negative regulation of G2/M transition of mitotic cell cycle

PSMD4 (3,208 words) [view diff] exact match in snippet view article find links to article

ubiquitin-dependent protein catabolic process Wnt signaling pathway, planar cell polarity pathway negative regulation of G2/M transition of mitotic cell cycle

Euprymna scolopes (2,343 words) [view diff] exact match in snippet view article find links to article

C.; McFall-Ngai, Margaret J. (2017-11-01). "Characterization of the cell polarity gene crumbs during the early development and maintenance of the squid–vibrio

Collective cell migration (2,239 words) [view diff] exact match in snippet view article find links to article

(2017). "Mathematical model of collective cell migrations based on cell polarity". Development, Growth & Differentiation. 59 (5): 471–490. doi:10.1111/dgd

PSMA7 (3,229 words) [view diff] exact match in snippet view article find links to article

protein catabolic process viral process Wnt signaling pathway, planar cell polarity pathway negative regulation of G2/M transition of mitotic cell cycle

PSMA3 (3,160 words) [view diff] exact match in snippet view article find links to article

endopeptidase activity viral process Wnt signaling pathway, planar cell polarity pathway proteasome-mediated ubiquitin-dependent protein catabolic process

HSP90AB1 (3,113 words) [view diff] exact match in snippet view article find links to article

surface central nervous system neuron axonogenesis establishment of cell polarity positive regulation of peptidyl-serine phosphorylation axon extension

SYNE2 (1,178 words) [view diff] exact match in snippet view article find links to article

centrosome localization nuclear migration establishment or maintenance of cell polarity protein localization to nucleus nucleokinesis involved in cell motility

PSMD14 (2,797 words) [view diff] exact match in snippet view article find links to article

regulation of endopeptidase activity Wnt signaling pathway, planar cell polarity pathway proteasome-mediated ubiquitin-dependent protein catabolic process

Theoretical neuromorphology (1,319 words) [view diff] exact match in snippet view article find links to article

membrane traffic at the synapse, on the development and maintenance of cell polarity and on the mechanisms responsible for the heterogeneous distribution

Cyclase-associated protein family (1,424 words) [view diff] exact match in snippet view article find links to article

morphological processes, including mRNA localisation and the establishment of cell polarity. Actin exists both as globular (G) (monomeric) actin subunits and assembled

PDZ domain (3,565 words) [view diff] exact match in snippet view article find links to article

PMID 9434904. Liu J, Li J, Ren Y, Liu P (2014-01-01). "DLG5 in cell polarity maintenance and cancer development". International Journal of Biological

PSMA4 (3,063 words) [view diff] exact match in snippet view article find links to article

protein catabolic process viral process Wnt signaling pathway, planar cell polarity pathway negative regulation of G2/M transition of mitotic cell cycle

Proteasome (prosome, macropain) subunit, alpha 1 (2,972 words) [view diff] exact match in snippet view article

ubiquitin-dependent protein catabolic process Wnt signaling pathway, planar cell polarity pathway negative regulation of G2/M transition of mitotic cell cycle

PSMA5 (2,993 words) [view diff] exact match in snippet view article find links to article

regulation of canonical Wnt signaling pathway Wnt signaling pathway, planar cell polarity pathway negative regulation of G2/M transition of mitotic cell cycle

PSMA6 (3,040 words) [view diff] exact match in snippet view article find links to article

ubiquitin-dependent protein catabolic process Wnt signaling pathway, planar cell polarity pathway negative regulation of G2/M transition of mitotic cell cycle

Contrast-induced nephropathy (2,316 words) [view diff] exact match in snippet view article find links to article

variety of mechanisms, one proposed mechanism is by causing changes in cell polarity. The sodium potassium pump (also known as the Na+/K+ ATPase) is redistributed

PSMD1 (3,214 words) [view diff] exact match in snippet view article find links to article

regulation of canonical Wnt signaling pathway Wnt signaling pathway, planar cell polarity pathway negative regulation of G2/M transition of mitotic cell cycle

PSMB2 (2,861 words) [view diff] exact match in snippet view article find links to article

ubiquitin-dependent protein catabolic process Wnt signaling pathway, planar cell polarity pathway viral process negative regulation of G2/M transition of mitotic

Auxin binding protein (1,593 words) [view diff] exact match in snippet view article find links to article

PMID 26467289. Pan X, Chen J, Yang Z (December 2015). "Auxin regulation of cell polarity in plants". Current Opinion in Plant Biology. Cell biology. 28: 144–153

PSMD7 (3,217 words) [view diff] exact match in snippet view article find links to article

ubiquitin-dependent protein catabolic process Wnt signaling pathway, planar cell polarity pathway negative regulation of G2/M transition of mitotic cell cycle

PSMB5 (3,119 words) [view diff] exact match in snippet view article find links to article

protein catabolic process viral process Wnt signaling pathway, planar cell polarity pathway negative regulation of G2/M transition of mitotic cell cycle

Stuart Schreiber (3,451 words) [view diff] exact match in snippet view article find links to article

was introduced in 2002 and has provided insights into tumorigenesis, cell polarity, and chemical space, among others. Using diversity-oriented synthesis

PSMB7 (3,313 words) [view diff] exact match in snippet view article find links to article

regulation of canonical Wnt signaling pathway Wnt signaling pathway, planar cell polarity pathway proteasome-mediated ubiquitin-dependent protein catabolic process

Ubiquitin B (996 words) [view diff] exact match in snippet view article find links to article

5'-to lesion ERBB2 signaling pathway Wnt signaling pathway, planar cell polarity pathway nucleotide-excision repair, preincision complex assembly proteasome-mediated

Progeria (6,284 words) [view diff] exact match in snippet view article find links to article

expression also leads to defects in the establishment of fibroblast cell polarity, which is also seen in physiological aging. To date, over 1,400 SNPs

PTK2 (4,671 words) [view diff] exact match in snippet view article find links to article

axonogenesis regulation of endothelial cell migration establishment of cell polarity regulation of focal adhesion assembly phosphorylation netrin-activated

PSMD10 (3,047 words) [view diff] exact match in snippet view article find links to article

signaling pathway transmembrane transport Wnt signaling pathway, planar cell polarity pathway regulation of transcription from RNA polymerase II promoter

Collective–amoeboid transition (311 words) [view diff] exact match in snippet view article find links to article

Aneta; Vomastek, Tomáš; Rosel, Daniel; Brábek, Jan (8 February 2016). "Cell polarity signaling in the plasticity of cancer cell invasiveness". Oncotarget

Aspergillus fumigatus (4,593 words) [view diff] exact match in snippet view article find links to article

2008). "A sterol-regulatory element binding protein is required for cell polarity, hypoxia adaptation, azole drug resistance, and virulence in Aspergillus

PSMB1 (3,183 words) [view diff] exact match in snippet view article find links to article

protein catabolic process viral process Wnt signaling pathway, planar cell polarity pathway negative regulation of G2/M transition of mitotic cell cycle

Dishevelled binding antagonist of beta catenin 1 (917 words) [view diff] exact match in snippet view article find links to article

protein catabolic process regulation of Wnt signaling pathway, planar cell polarity pathway negative regulation of Wnt signaling pathway regulation of nodal

Microtubule (7,911 words) [view diff] exact match in snippet view article find links to article

stable modified microtubules are typically oriented towards the site of cell polarity in interphase cells, this subset of modified microtubules provide a

Peptide amphiphile (2,114 words) [view diff] exact match in snippet view article find links to article

and suggest several applications in regenerating tissues that rely on cell polarity and alignment for function. In another study, the combination of positively

PSMB6 (3,462 words) [view diff] exact match in snippet view article find links to article

protein catabolic process viral process Wnt signaling pathway, planar cell polarity pathway negative regulation of G2/M transition of mitotic cell cycle

Lens (vertebrate anatomy) (6,533 words) [view diff] exact match in snippet view article

Herman, Ken; Plageman, Timothy F. (April 2016). "Lens placode planar cell polarity is dependent on Cdc42-mediated junctional contraction inhibition". Developmental

PSMD2 (3,563 words) [view diff] exact match in snippet view article find links to article

regulation of canonical Wnt signaling pathway Wnt signaling pathway, planar cell polarity pathway negative regulation of G2/M transition of mitotic cell cycle

PSMB4 (3,031 words) [view diff] exact match in snippet view article find links to article

protein catabolic process viral process Wnt signaling pathway, planar cell polarity pathway negative regulation of G2/M transition of mitotic cell cycle

PSMB10 (3,483 words) [view diff] exact match in snippet view article find links to article

signaling pathway transmembrane transport Wnt signaling pathway, planar cell polarity pathway regulation of transcription from RNA polymerase II promoter

CRKL (3,165 words) [view diff] exact match in snippet view article find links to article

hippocampus development cerebral cortex development establishment of cell polarity regulation of cell adhesion mediated by integrin helper T cell diapedesis

Sonic hedgehog protein (7,452 words) [view diff] exact match in snippet view article find links to article

cell proliferation involved in ureter development establishment of cell polarity branching involved in blood vessel morphogenesis positive regulation

Germ-band extension (1,096 words) [view diff] exact match in snippet view article find links to article

Zallen, J.A. (2006). "Multicellular rosette formation links planar cell polarity to tissue morphogenesis". Developmental Cell. 11 (4): 459–470. doi:10

Glypican 3 (2,651 words) [view diff] exact match in snippet view article find links to article

regulation of growth positive regulation of Wnt signaling pathway, planar cell polarity pathway anterior/posterior axis specification negative regulation of

RUFY2 (1,357 words) [view diff] case mismatch in snippet view article find links to article

(2013). "RUFY, Rab and Rap Family Proteins Involved in a Regulation of Cell Polarity and Membrane Trafficking". International Journal of Molecular Sciences

Mental retardation and microcephaly with pontine and cerebellar hypoplasia (2,058 words) [view diff] exact match in snippet view article find links to article

"Genetic studies define MAGUK proteins as regulators of epithelial cell polarity". The International Journal of Developmental Biology. 46 (4): 511–518

Allomyces macrogynus (1,568 words) [view diff] exact match in snippet view article find links to article

R.; Gooday, G. W. (1988). "Bioelectric and biosynthetic aspects of cell polarity inAllomyces macrogynus". Protoplasma. 146 (2–3): 118–126. doi:10.1007/BF01405920

PSMC1 (3,859 words) [view diff] exact match in snippet view article find links to article

pathway negative regulation of neuron death Wnt signaling pathway, planar cell polarity pathway positive regulation of proteasomal protein catabolic process

Cordon-bleu protein (2,680 words) [view diff] exact match in snippet view article find links to article

defects in the inner ear suggesting a role of Cobl in postnatal planar cell polarity refinements and in the organization of the sensory structures in the

Adapter molecule crk (2,943 words) [view diff] exact match in snippet view article find links to article

hippocampus development cerebral cortex development establishment of cell polarity regulation of cell adhesion mediated by integrin helper T cell diapedesis

Histopathology of colorectal adenocarcinoma (2,114 words) [view diff] exact match in snippet view article find links to article

of juxtaposed gland lumens without stroma in between, with loss of cell polarity. Rarely, they have foci of squamous differentiation (morules). This

PSMB8 (3,957 words) [view diff] exact match in snippet view article find links to article

protein catabolic process viral process Wnt signaling pathway, planar cell polarity pathway negative regulation of G2/M transition of mitotic cell cycle

PSMB9 (3,811 words) [view diff] exact match in snippet view article find links to article

protein catabolic process viral process Wnt signaling pathway, planar cell polarity pathway negative regulation of G2/M transition of mitotic cell cycle

Magdalena Żernicka-Goetz (2,214 words) [view diff] exact match in snippet view article find links to article

regulation at the 4-cell stage that directs a molecular cascade establishing cell polarity, position and fate. Her recent development of systems permitting both

Helicobacter pylori (16,816 words) [view diff] exact match in snippet view article find links to article

cytoskeleton, adherence to adjacent cells, intracellular signaling, cell polarity, and other cellular activities. Once inside the cell, the CagA protein

MYH9 (6,056 words) [view diff] exact match in snippet view article find links to article

localization blood vessel endothelial cell migration establishment of T cell polarity myoblast fusion membrane protein ectodomain proteolysis actomyosin structure

Alexander F. Schier (1,852 words) [view diff] exact match in snippet view article find links to article

B., Jenny, A., Lee, D., Mlodzik, M. and Schier, A.F. (2006). Planar cell polarity signalling couples cell division and morphogenesis during neurulation

Dactylellina haptotyla (1,433 words) [view diff] exact match in snippet view article find links to article

expressed in mycelium and knobs. Some of those genes are responsible for cell polarity regulation. For example, profilin and cofilin are downregulated in knobs

Richard Carthew (1,993 words) [view diff] exact match in snippet view article find links to article

first to establish the Drosophila eye as a model system to study planar cell polarity. It was the first group to use Drosophila as a disease model to screen

Locomotor effects of shoes (2,842 words) [view diff] exact match in snippet view article find links to article

Nathans, Jeremy (ed.). "Cells must express components of the planar cell polarity system and extracellular matrix to support cytonemes". eLife. 5: e18979

MDia1 (1,955 words) [view diff] case mismatch in snippet view article find links to article

Hashimoto N, Matsuda M, Narumiya S (2006). "The Rho-mDia1 Pathway Regulates Cell Polarity and Focal Adhesion Turnover in Migrating Cells through Mobilizing Apc

Catenin alpha-1 (2,782 words) [view diff] exact match in snippet view article find links to article

regulation of neuroblast proliferation establishment or maintenance of cell polarity positive regulation of extrinsic apoptotic signaling pathway in absence

FAM203B (1,501 words) [view diff] exact match in snippet view article find links to article

Ahringer J (January 2013). "Systematic genetic interaction screens uncover cell polarity regulators and functional redundancy". Nature Cell Biology. 15 (1):

Ubiquitin C (4,261 words) [view diff] exact match in snippet view article find links to article

repair, preincision complex assembly Wnt signaling pathway, planar cell polarity pathway proteasome-mediated ubiquitin-dependent protein catabolic process

Polar organelle (2,509 words) [view diff] exact match in snippet view article find links to article

important in medical bacteriology, as many virulence factors are linked to cell polarity. FlhFG acts as a GTPase, which plays a crucial role in the development

Heat shock protein 90kDa alpha (cytosolic), member A1 (8,199 words) [view diff] exact match in snippet view article

pathway central nervous system neuron axonogenesis establishment of cell polarity positive regulation of protein polymerization positive regulation of

Cell biomechanics (3,022 words) [view diff] case mismatch in snippet view article find links to article

exploring cell and tissue mechanics in vivo", Methods in Cell Biology, Cell Polarity and Morphogenesis, 139, Academic Press: 187–201, doi:10.1016/bs.mcb

Amy Gladfelter (2,167 words) [view diff] exact match in snippet view article find links to article

proteins can permit autonomy among syncytial nuclei and help to establish cell polarity. Recently, the lab has begun examining phase separation in the context

Biochemical cascade (11,432 words) [view diff] exact match in snippet view article find links to article

transcription factor. The non-canonical Wnt signaling can be divided in planar cell polarity (PCP) pathway and Wnt/calcium pathway. It is characterized by binding

List of model organisms (4,711 words) [view diff] exact match in snippet view article find links to article

mushroom formation. Schizosaccharomyces pombe, fission yeast, (cell cycle, cell polarity, RNAi, centromere structure and function, transcription). Ustilago maydis

Mendel Lectures (857 words) [view diff] case mismatch in snippet view article find links to article

Mlodzik Icahn School of Medicine at Mount Sinai, USA "Wnt/Frizzled Planar Cell Polarity signaling in development and disease" 18 126 March 17, 2022 Ben Feringa

NEDD9 (8,012 words) [view diff] exact match in snippet view article find links to article

and screened for genes that simultaneously affected cell cycle and cell polarity controls, inducing a filamentous yeast budding phenotype, and thus identified

3D cell culture (7,831 words) [view diff] exact match in snippet view article find links to article

and is more relevant physiologically in cytoskeletal organization and cell polarity and shape of human cells. The three-dimensional arrangement allows the

Jeff Wrana (1,557 words) [view diff] exact match in snippet view article find links to article

cancer cells, promoting metastasis through induction of the core planar cell polarity pathway. In 2015, Wrana was appointed the inaugural CIBC Scientist in

Multi-state modeling of biomolecules (6,761 words) [view diff] exact match in snippet view article find links to article

PMC 3507550. PMID 22683827. Mogilner A, Allard J, Wollman R (April 2012). "Cell polarity: quantitative modeling as a tool in cell biology". Science. 336 (6078):

Clathrin-independent endocytosis (1,994 words) [view diff] exact match in snippet view article find links to article

2020). "Clathrin-independent endocytosis, retrograde trafficking, and cell polarity". Current Opinion in Cell Biology. 65: 112–121. doi:10.1016/j.ceb.2020

Meng Anming (3,279 words) [view diff] exact match in snippet view article find links to article

signalling receptor MCAM coordinates apical-basal polarity and planar cell polarity during morphogenesis". Nature Communications. 8 (1): 15279. Bibcode:2017NatCo

Nucleariid (2,905 words) [view diff] exact match in snippet view article find links to article

of nucleariids, however, had lost the opisthokont flagellum and its cell polarity, and had gained the characteristic mucous coat. The presence of filopodia