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searching for Polycystin 1 15 found (22 total)

PKD1L1 (195 words) [view diff] exact match in snippet view article find links to article

Polycystin 1 like 1, transient receptor potential channel interacting is a protein that in humans is encoded by the PKD1L1 gene. This gene encodes a member

TRPP (427 words) [view diff] no match in snippet view article find links to article

disease 1 (PKD1)-like, contains polycystin-1 (Previously known as TRPP1), PKDREJ, PKD1L1, PKD1L2, and PKD1L3. Polycystin-1 contains numerous N-terminal adhesive

Polycystin cation channel family (1,389 words) [view diff] exact match in snippet view article find links to article

3TE3, 4GIF PKD2: PDB: 2KLD, 2KLE, 3HRN, 3HRO, 2KQ6, 2Y4Q Human polycystin 1 is a huge protein of 4303 amino acyl residues (aas). Its repeated leucine-rich

EPCIP (gene) (972 words) [view diff] no match in snippet view article

Exosomal polycystin-1-interacting protein is a protein that, in humans, is encoded by the EPCIP gene. EPCIP is found on human chromosome 21, and it is

M. Amin Arnaout (722 words) [view diff] no match in snippet view article find links to article

for a routinely used diagnostic assay. He was the first to show that polycystin-1, one of two gene products mutated in patients with Autosomal Dominant

GAIN domain (267 words) [view diff] no match in snippet view article find links to article

"The Role of G-Protein-Coupled Receptor Proteolysis Site Cleavage of Polycystin-1 in Renal Physiology and Polycystic Kidney Disease". Cells. 5 (1): 3.

Zinc-dependent phospholipase C (480 words) [view diff] no match in snippet view article find links to article

Hofmann K, Bork P (August 1999). "A latrophilin/CL-1-like GPS domain in polycystin-1". Curr. Biol. 9 (16): R585–8. doi:10.1016/S0960-9822(99)80379-0. PMID 10469603

Autosomal dominant polycystic kidney disease (7,139 words) [view diff] no match in snippet view article find links to article

intercalated cells) show the presence of a single primary apical cilium. Polycystin-1, the protein encoded by the PKD1 gene, is present on these cilia and

RVxP motif (1,468 words) [view diff] no match in snippet view article find links to article

signal and GTPase complex are required for the ciliary transport of polycystin-1". Molecular Biology of the Cell. 22 (18): 3298. doi:10.1091/mbc.e11-01-0082

Chromosome 21 (3,068 words) [view diff] no match in snippet view article find links to article

tyrosine-(Y)-phosphorylation regulated kinase 1A EPCIP: encoding exosomal polycystin-1-interacting protein ERG: encoding protein transcriptional regulator ERG

PKD2L1 (712 words) [view diff] no match in snippet view article find links to article

Yu Z, et al. (2006). "Polycystin-2 traffics to cilia independently of polycystin-1 by using an N-terminal RVxP motif". J. Cell Sci. 119 (Pt 7): 1383–95

ARF4 (1,004 words) [view diff] no match in snippet view article find links to article

signal and GTPase complex are required for the ciliary transport of polycystin-1". Molecular Biology of the Cell. 22 (18): 3289–3305. doi:10.1091/mbc

Ciliopathy (2,341 words) [view diff] no match in snippet view article find links to article

ciliopathy is ADPKD, which is caused by mutations in PKD1 and PKD2, encoding polycystin-1 and -2, respectively. These proteins are essential for the mechanosensory

Catenin beta-1 (12,516 words) [view diff] no match in snippet view article find links to article

Li HP, Wilson PD (December 2000). "Modification of the composition of polycystin-1 multiprotein complexes by calcium and tyrosine phosphorylation". Biochimica

Folliculin (5,698 words) [view diff] exact match in snippet view article find links to article

regulate formation of the primary cilium via a rapamycin-insensitive and polycystin 1-independent pathway". Human Molecular Genetics. 18 (1): 151–63. doi:10