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searching for Mitotic exit 32 found (37 total)

alternate case: mitotic exit

Biochemical switches in the cell cycle (6,676 words) [view diff] exact match in snippet view article find links to article

triggering irreversible mitotic exit. Clb2 degradation did shorten the Cdk1-inhibition period required for triggering irreversible mitotic exit indicating that
Cdc14 (2,755 words) [view diff] exact match in snippet view article find links to article
understood and most-studied, the activity of Cdc14 (ScCdc14) leads to mitotic exit by dephosphorylating targets of Cdk1, a well-studied cyclin-dependent
Telophase (2,649 words) [view diff] exact match in snippet view article find links to article
seen in budding yeast, which do not have redundant phosphatases for mitotic exit and rely on the phosphatase cdc14. Blocking cdc14 activation in these
Polo-like kinase (1,469 words) [view diff] exact match in snippet view article find links to article
serine/threonin kinases of the cell cycle involved in mitotic entry, mitotic exit, spindle formation, cytokinesis, and meiosis. Only one Plk is found in
BUB3 (2,194 words) [view diff] exact match in snippet view article find links to article
Anaphase Promoting Complex (APC), preventing early anaphase entry and mitotic exit; this serves as a mechanism for the fidelity of chromosomal segregation
CellCognition (461 words) [view diff] exact match in snippet view article find links to article
imaging RNAi screen identifies PP2A-B55alpha and importin-beta1 as key mitotic exit regulators in human cells". Nature Cell Biology. 12 (9): 886–93. doi:10
TPX2 (4,937 words) [view diff] exact match in snippet view article find links to article
regulated by the APC/CCdh1 pathway. The instability and drop in TPX2 at mitotic exit is dependent on both the anaphase-promoting complex/cyclosome (APC/C)
CDC14B (753 words) [view diff] exact match in snippet view article find links to article
"Role for human SIRT2 NAD-dependent deacetylase activity in control of mitotic exit in the cell cycle". Mol. Cell. Biol. 23 (9): 3173–3185. doi:10.1128/MCB
Anaphase-promoting complex (4,164 words) [view diff] exact match in snippet view article find links to article
extracts can prevent the destruction of endogenous cyclin A, cyclin B, and mitotic exit, suggesting that Emi1 is able to counteract the activity of the APC.
RPS6KA2 (1,057 words) [view diff] exact match in snippet view article find links to article
in Swiss 3T3 cells: a role for the MAP kinase pathway in regulating mitotic exit". Cell. Signal. 13 (9): 653–64. doi:10.1016/S0898-6568(01)00185-1. PMID 11495723
LATS1 (1,108 words) [view diff] exact match in snippet view article find links to article
PMID 16007220. Bothos J, Tuttle RL, Ottey M, et al. (2005). "Human LATS1 is a mitotic exit network kinase". Cancer Res. 65 (15): 6568–75. doi:10.1158/0008-5472
FOXM1 (1,468 words) [view diff] exact match in snippet view article find links to article
Alvarez-Fernandez M, Stahl M, Medema RH (September 2008). "FoxM1 is degraded at mitotic exit in a Cdh1-dependent manner". Cell Cycle. 7 (17): 2720–6. doi:10.4161/cc
Sirtuin 2 (3,647 words) [view diff] exact match in snippet view article find links to article
"Role for human SIRT2 NAD-dependent deacetylase activity in control of mitotic exit in the cell cycle". Molecular and Cellular Biology. 23 (9): 3173–85.
Sirtuin (2,683 words) [view diff] exact match in snippet view article find links to article
"Role for human SIRT2 NAD-dependent deacetylase activity in control of mitotic exit in the cell cycle". Molecular and Cellular Biology. 23 (9): 3173–85.
Whi5 (1,141 words) [view diff] exact match in snippet view article find links to article
nucleus. Whi5 is in the nucleus in late mitosis and G1 phase. Once the mitotic exit network is activated and CDK activity is reduced, Whi5 enters the nucleus
CKAP2 (809 words) [view diff] exact match in snippet view article find links to article
"CKAP2 is a spindle-associated protein degraded by APC/C-Cdh1 during mitotic exit". J. Biol. Chem. 282 (20): 15103–13. doi:10.1074/jbc.M701688200. PMID 17376772
Raymond J. Deshaies (2,447 words) [view diff] exact match in snippet view article find links to article
protein Net1 in late anaphase, which is triggered by the action of the mitotic exit network (MEN). In later work, they established that an early step in
Cyclin-dependent kinase 1 (2,883 words) [view diff] exact match in snippet view article find links to article
cyclins leads to the final events of mitosis (e.g., spindle disassembly, mitotic exit). Given its essential role in cell cycle progression, Cdk1 is highly
CDH1 (gene) (3,836 words) [view diff] exact match in snippet view article
Alvarez-Fernandez M, Stahl M, Medema RH (September 2008). "FoxM1 is degraded at mitotic exit in a Cdh1-dependent manner". Cell Cycle. 7 (17): 2720–6. doi:10.4161/cc
PRC1 (1,773 words) [view diff] exact match in snippet view article find links to article
and G2/M phases of the cell cycle before dropping dramatically after mitotic exit and entrance into G1 phase. PRC1 is located in the nucleus during interphase
Aurora A kinase (2,705 words) [view diff] exact match in snippet view article find links to article
remains associated with the spindles through telophase. Right before mitotic exit, Aurora A relocalizes to the mid-zone of the spindle. During mitosis
Rong Li (2,694 words) [view diff] exact match in snippet view article find links to article
subsequently made a number of significant discoveries in the area of mitotic exit control and cytokinesis. She is recognized as a leader in the study of
Angelika Amon (2,283 words) [view diff] case mismatch in snippet view article find links to article
Tyers, Mike; Amon, Angelika (1998). "The Phosphatase Cdc14 Triggers Mitotic Exit by Reversal of Cdk-Dependent Phosphorylation". Molecular Cell. 2 (6):
P21 (3,907 words) [view diff] case mismatch in snippet view article find links to article
Proliferation-Quiescence Decision Is Controlled by a Bifurcation in CDK2 Activity at Mitotic Exit". Cell. 155 (2): 369–383. doi:10.1016/j.cell.2013.08.062. PMC 4001917
Mitosis (7,209 words) [view diff] exact match in snippet view article find links to article
signaling pathway that allows a single unattached kinetochore to inhibit mitotic exit". Progress in Cell Cycle Research. 5: 431–9. PMID 14593737. FitzHarris
Cell synchronization (2,120 words) [view diff] exact match in snippet view article find links to article
including the G2/M transition, the metaphase/anaphase transition, and mitotic exit. Nocodazole is a rapidly-reversible inhibitor of microtubule polymerization
TRIP13 (1,821 words) [view diff] case mismatch in snippet view article find links to article
(May 2017). "Mad2 Overexpression Uncovers a Critical Role for TRIP13 in Mitotic Exit". Cell Reports. 19 (9): 1832–1845. doi:10.1016/j.celrep.2017.05.021.
ANLN (2,956 words) [view diff] exact match in snippet view article find links to article
Rho-kinase. It has been observed that anillin proteolysis is triggered after mitotic exit by the Anaphase Promoting Complex (APC). Most anillins can be sequestered
Live single-cell imaging (2,110 words) [view diff] case mismatch in snippet view article find links to article
Proliferation-Quiescence Decision Is Controlled by a Bifurcation in CDK2 Activity at Mitotic Exit". Cell. 155 (2): 369–383. doi:10.1016/j.cell.2013.08.062. PMC 4001917
BTRC (gene) (3,341 words) [view diff] exact match in snippet view article
anaphase-metaphase transition (by inducing the proteolysis of Securin) and mitotic exit (by driving the degradation of mitotic CDK1 activating cyclin subunits)
FBXW11 (3,034 words) [view diff] exact match in snippet view article find links to article
anaphase-metaphase transition (by inducing the proteolysis of Securin) and mitotic exit (by driving the degradation of mitotic CDK1 activating cyclin subunits)
C8orf34 (2,299 words) [view diff] exact match in snippet view article find links to article
Hu Z, Li H, Li J (June 2017). "Pre-RC Protein MCM7 depletion promotes mitotic exit by Inhibiting CDK1 activity". Scientific Reports. 7 (1): 2854. Bibcode:2017NatSR