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searching for Adaptive immune system 93 found (277 total)

Receptor editing (283 words) [view diff] exact match in snippet view article find links to article

occurs during the maturation of B cells, which are part of the adaptive immune system. This process forms part of central tolerance to attempt to change

Severe combined immunodeficiency (non-human) (1,429 words) [view diff] exact match in snippet view article

disorder that is characterized by the complete inability of the adaptive immune system to mount, coordinate, and sustain an appropriate immune response

Giardiasis (5,501 words) [view diff] no match in snippet view article find links to article

Giardiasis is a parasitic disease caused by Giardia duodenalis (also known as G. lamblia and G. intestinalis). Infected individuals who experience symptoms

Phase variation (1,663 words) [view diff] exact match in snippet view article find links to article

one type of flagellin, or if a previous encounter has left the adaptive immune system ready to deal with one type of flagellin, switching types renders

CRISPR RNA (1,149 words) [view diff] exact match in snippet view article find links to article

interspaced short palindromic repeats - CRISPR associated systems) is an adaptive immune system found in bacteria and archaea to protect against mobile genetic

Susumu Tonegawa (1,605 words) [view diff] exact match in snippet view article find links to article

Tonegawa's Nobel Prize work elucidated the genetic mechanism of the adaptive immune system, which had been the central question of immunology for over 100

Tulane University School of Medicine (1,951 words) [view diff] exact match in snippet view article find links to article

monumental achievement that provided the organizing principle of the adaptive immune system and launched the course of modern immunology Harold Cummins, M.D

Type I hypersensitivity (840 words) [view diff] case mismatch in snippet view article find links to article

(1–2): 43–49. doi:10.1016/S0300-483X(00)00400-5. PMID 11164991. "The Adaptive Immune System: Type I Immediate Hypersensitivity". Archived from the original

Haematopoietic system (1,205 words) [view diff] exact match in snippet view article find links to article

rate of erythropoiesis. Lymphocytes are the cornerstone of the adaptive immune system. They are derived from common lymphoid progenitors. The lymphoid

Robert D. Schreiber (1,006 words) [view diff] exact match in snippet view article find links to article

paper, Stutman tested whether athymic, nude mice which lack an adaptive immune system have an increased incidence of tumors. His finding that the incidence

Cas9 (5,896 words) [view diff] exact match in snippet view article find links to article

Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) adaptive immune system in Streptococcus pyogenes. S. pyogenes utilizes CRISPR to memorize

Urticarial vasculitis (715 words) [view diff] exact match in snippet view article find links to article

system – the innate immune system: a broad defence system; and the adaptive immune system: the strong immune response capable of remembering previous infections

Immunopathology (1,245 words) [view diff] exact match in snippet view article find links to article

considered nonspecific. It is usually a more immediate response than the adaptive immune system, usually responding within minutes to hours. It is composed of physical

Streptamer (613 words) [view diff] exact match in snippet view article find links to article

and basic T-cell research. T cells play an important role in the adaptive immune system. They are capable of orchestrating, regulating and coordinating

Ectopic thymus (1,055 words) [view diff] exact match in snippet view article find links to article

likely be left to involute. Given the thymus's role in the body's adaptive immune system, it should be confirmed that the patient has a mediastinal thymus

Non-peptidic antigen (303 words) [view diff] exact match in snippet view article find links to article

Antigen recognition by human γδ T cells: pattern recognition by the adaptive immune system. Springer Semin Immunopathol. 2000;22:191-217. PMID 11116953 Eberl

Animal virus (1,974 words) [view diff] exact match in snippet view article find links to article

Invertebrates do not produce antibodies by the lymphocyte-based adaptive immune system that is central to vertebrate immunity, but they are capable of

NLRC5 (798 words) [view diff] exact match in snippet view article find links to article

I (MHCI) molecule expression, playing a significant role in the adaptive immune system. This aspect of NLRC5 function was further investigated with the

Northwest Biotherapeutics (1,104 words) [view diff] exact match in snippet view article find links to article

Dr. Ralph Steinman, dendritic cells act as the general for the adaptive immune system. They educate and direct T-Cells and other immune system cells to

Outline of medicine (2,089 words) [view diff] exact match in snippet view article find links to article

Immunology – study of the immune system, which includes the innate and adaptive immune system in humans, for example. Laboratory medical biology Microbiology

HIV vaccine development (5,629 words) [view diff] exact match in snippet view article find links to article

vaccine would be available within two years. However, priming the adaptive immune system to recognize the viral envelope proteins did not prevent HIV acquisition

Lingyin Li (1,080 words) [view diff] exact match in snippet view article find links to article

inflammatory proteins that trigger the adaptive immune system. The combination of the innate and adaptive immune system eliminates pathogens and is predicted

Abscopal effect (1,126 words) [view diff] exact match in snippet view article find links to article

mediated by the immune system. Here, local radiation causes tumor cell death, which is followed by adaptive immune system recognition, not unlike a vaccine.

Jan Klein (4,880 words) [view diff] exact match in snippet view article find links to article

textbook sections emphasizing the importance of the so-called non-adaptive immune system (NAIS; he preferred to call it non-anticipatory). He also gave immunology

Jacques Miller (1,207 words) [view diff] exact match in snippet view article find links to article

that the thymus is vital for the development and function of the adaptive immune system. Prior to this, the thymus was believed to be a vestigial organ

CD79A (2,434 words) [view diff] exact match in snippet view article find links to article

Flajnik MF, Kasahara M (January 2010). "Origin and evolution of the adaptive immune system: genetic events and selective pressures". Nature Reviews. Genetics

Animal testing on invertebrates (899 words) [view diff] exact match in snippet view article find links to article

development of nerves to be studied in detail. However, the lack of an adaptive immune system and the simplicity of its organs prevent C. elegans from being used

Severe combined immunodeficient mice (1,209 words) [view diff] exact match in snippet view article find links to article

that some mice with SCIDs do in fact have a somewhat functional adaptive immune system. There are many types of SCID mice used by researchers at present

Autoimmune disease in women (5,184 words) [view diff] exact match in snippet view article find links to article

of human biology, including the development and response of the adaptive immune system. Sex hormones such as estrogen, progesterone, and testosterone are

MHC restriction (2,238 words) [view diff] exact match in snippet view article find links to article

Martin F.; Kasahara, Masanori (2010). "Origin and evolution of the adaptive immune system: genetic events and selective pressures". Nature Reviews Genetics

Trodusquemine (1,135 words) [view diff] exact match in snippet view article find links to article

for antimicrobial compounds in Squaliformes, which lack a robust adaptive immune system. It was hypothesized that their innate immunity might be conferred

Skin sloughing (1,148 words) [view diff] exact match in snippet view article find links to article

proliferation.[citation needed] Generally, psoriasis affects innate and adaptive immune system cells. Cells that are impacted in psoriasis include dendritic cells

Lasker Award (1,590 words) [view diff] exact match in snippet view article find links to article

monumental achievement that provided the organizing principle of the adaptive immune system and launched the course of modern immunology. Jacques Miller Clinical

Neuroimmune system (3,180 words) [view diff] exact match in snippet view article find links to article

involved in neurogenesis. Studies have shown that during times of adaptive immune system response, hippocampal neurogenesis is increased, and conversely

Sequence homology (4,302 words) [view diff] exact match in snippet view article find links to article

"Comparative genomics of the MHC: glimpses into the evolution of the adaptive immune system". Immunity. 15 (3): 351–62. doi:10.1016/S1074-7613(01)00198-4. PMID 11567626

Ellen Heber-Katz (1,538 words) [view diff] exact match in snippet view article find links to article

fundamental understanding of how ‘foreign’ antigens activate the adaptive immune system in mammals. In 1976, Heber-Katz was appointed as the Assistant Professor

Margaret Ackerman (740 words) [view diff] exact match in snippet view article find links to article

early response system that protects us from pathogens until our adaptive immune system responds. The ability of antibodies to recruit an innate immune

TRPV2 (2,673 words) [view diff] exact match in snippet view article find links to article

where T cells mature. T cells are an important component to the adaptive immune system, because it is where the body adapts to foreign substances; this

Retinal gene therapy using lentiviral vectors (1,503 words) [view diff] exact match in snippet view article find links to article

them falling under either activity by the innate immune system or adaptive immune system. In the cases of some HIV-1-derived lentiviral vectors, both immune

Katherine Belov (1,372 words) [view diff] exact match in snippet view article find links to article

Genetics, genomics, marsupial and monotreme genomics, evolution of the adaptive immune system Notable works Genetics of Tasmanian devil facial tumor disease

Heterosis (4,525 words) [view diff] exact match in snippet view article find links to article

each parent, which are used in antigen presentation as part of the adaptive immune system. Each different copy of the genes is able to bind and present a

STAT2 (3,261 words) [view diff] exact match in snippet view article find links to article

for patients with STAT2 deficiency during childhood, until their adaptive immune system has sufficiently developed. From the age 5 years, the frequency

2R hypothesis (2,201 words) [view diff] exact match in snippet view article find links to article

"Comparative genomics of the MHC: glimpses into the evolution of the adaptive immune system". Immunity. 15 (3): 351–62. doi:10.1016/S1074-7613(01)00198-4. PMID 11567626

Pre-metastatic niche (1,586 words) [view diff] exact match in snippet view article find links to article

by the tumor, can protect the cancer cells from detection by the adaptive immune system, which would otherwise be halting metastasis. Myeloid progenitor

Network of Cancer Genes (1,570 words) [view diff] exact match in snippet view article find links to article

Mamie Z.; Haigis, Kevin M.; Elledge, Stephen J. (2021-09-17). "The adaptive immune system is a major driver of selection for tumor suppressor gene inactivation"

Guide RNA (3,643 words) [view diff] exact match in snippet view article find links to article

short palindromic repeats) and its associated Cas enzymes, as their adaptive immune system. When prokaryotes are infected by phages, and manage to fend off

T cell receptor revision (1,333 words) [view diff] exact match in snippet view article find links to article

generating much higher T cell plasticity in the development of the adaptive immune system than we have previously anticipated. Activation-dependent T cell

Jeffrey I. Gordon (1,908 words) [view diff] exact match in snippet view article find links to article

habitat. This approach has been extended to describe the role of the adaptive immune system in maintaining the host-microbial relationship. Gordon is the lead

EF-Tu receptor (1,511 words) [view diff] exact match in snippet view article find links to article

immune cells that can travel this way. Plants also do not have an adaptive immune system, so other forms of immunity are required. One is the use of pattern-recognition

CRISPR interference (2,898 words) [view diff] exact match in snippet view article find links to article

genes on the mRNA level. Many bacteria and most archaea have an adaptive immune system which incorporates CRISPR RNA (crRNA) and CRISPR-associated (cas)

Matthew Tirrell (1,267 words) [view diff] exact match in snippet view article find links to article

to diagnose and treat atherosclerosis, and also to stimulate the adaptive immune system to generate desired B-cell and T-cell responses. The other principal

Heat shock protein (5,533 words) [view diff] exact match in snippet view article find links to article

"Functions of heat shock proteins in pathways of the innate and adaptive immune system". Journal of Immunology. 193 (12): 5765–5771. doi:10.4049/jimmunol

RNA interference (15,409 words) [view diff] exact match in snippet view article find links to article

divided into two separate branches: the innate immune system and the adaptive immune system. The innate immune system is the first defense against infection

Medicine (9,787 words) [view diff] exact match in snippet view article find links to article

is the study of the immune system, which includes the innate and adaptive immune system in humans, for example. Lifestyle medicine is the study of the chronic

Adenosine A2A receptor (5,207 words) [view diff] exact match in snippet view article find links to article

A2A receptor has also been shown to play a regulatory role in the adaptive immune system. In this role, it functions similarly to programmed cell death-1

List of primary immunodeficiencies (1,836 words) [view diff] exact match in snippet view article find links to article

Otulipenia/ORAS The complement system is part of the innate as well as the adaptive immune system; it is a group of circulating proteins that can bind pathogens and

Plant disease epidemiology (2,369 words) [view diff] exact match in snippet view article find links to article

move and fight foreign organisms and they do not have a somatic adaptive immune system, they do have and depend on innate immunity of each cell and on

HFE H63D gene mutation (2,659 words) [view diff] exact match in snippet view article find links to article

autoimmune reactions, including periods of decreased defense of the adaptive immune system. Fibrosis in various organ systems, including the skin. Impaired

Cd1-restricted T cell (1,585 words) [view diff] exact match in snippet view article find links to article

generated by somatic DNA rearrangement, a hallmark of cells of the adaptive immune system. A hallmark of NKT cells is their capacity to rapidly produce copious

Reactive oxygen species (8,460 words) [view diff] exact match in snippet view article find links to article

platelets to sites of injury. These also provide a link to the adaptive immune system via the recruitment of leukocytes.[citation needed] Reactive oxygen

Pattern recognition receptor (5,846 words) [view diff] exact match in snippet view article find links to article

innate immune system while NBS-LRR proteins are initiated in the adaptive immune system called the effector-triggered immunity. PRRs commonly associate

Macrophage (10,341 words) [view diff] exact match in snippet view article find links to article

cells, which serves as an important source of IFN-γ before the adaptive immune system is activated. IFN-γ enhances the innate immune response by inducing

Dennis Kasper (1,417 words) [view diff] exact match in snippet view article find links to article

2011). "A mechanism for glycoconjugate vaccine activation of the adaptive immune system and its implications for vaccine design". Nature Medicine. 17 (12):

Genome evolution in seadragons (1,798 words) [view diff] exact match in snippet view article find links to article

immunologic tolerance in embryos, before they develop their own adaptive immune system. The most recently discovered species is the ruby seadragon, whose

DNA vaccine (8,378 words) [view diff] exact match in snippet view article find links to article

and uptake into target cells. The innate system works with the adaptive immune system to mount a response against the DNA encoded protein. CpG-S sequences

Agent-based model (9,186 words) [view diff] exact match in snippet view article find links to article

example, in a study about CD4+ T cells (a key cell type in the adaptive immune system), the researchers modelled biological phenomena occurring at different

Altered Schaedler flora (2,578 words) [view diff] exact match in snippet view article find links to article

signaling. In another study, the innate detection system generates adaptive immune system to maintain intestinal homeostasis. Geuking, et al. examined the

Glossary of biology (11,418 words) [view diff] exact match in snippet view article find links to article

links B cell A type of lymphocyte in the humoral immunity of the adaptive immune system. bacteria An enormous and diverse clade of microscopic, prokaryotic

Sankar Ghosh (2,448 words) [view diff] exact match in snippet view article find links to article

identification and characterization of signaling intermediates in innate and adaptive immune system, and identification and characterization of a subset of Toll-like

Morphine (13,882 words) [view diff] exact match in snippet view article find links to article

proliferation, growth, and differentiation of T-cells (another cell of the adaptive immune system) and less interleukin-10 (IL-10), a cytokine responsible for promoting

Lynn Corcoran (758 words) [view diff] exact match in snippet view article find links to article

interested in the biology of B lymphocytes, effector cells of the adaptive immune system. They are generated in bone marrow, migrate to the periphery, and

CRISPR gene editing (20,481 words) [view diff] exact match in snippet view article find links to article

Danisco France SAS displayed experimentally how CRISPR systems are an adaptive immune system, and integrate new phage DNA into the CRISPR array, which is how

K. Christopher Garcia (2,327 words) [view diff] exact match in snippet view article find links to article

proving that CD47-based therapy relies upon stimulation of the adaptive immune system. Garcia's lab published the creation of an "orthogonal" IL-2 receptor

Genetic engineering techniques (6,765 words) [view diff] exact match in snippet view article find links to article

repeat / CRISPR associated protein) systems that function as an adaptive immune system in bacteria and archaea. The CRISPR/Cas system allows bacteria and

Blood transfusion (14,319 words) [view diff] exact match in snippet view article find links to article

different cancer types, through mechanisms involving the innate and adaptive immune system. Five major mechanisms for this include the lymphocyte-T set, myeloid-derived

CRISPR (13,613 words) [view diff] exact match in snippet view article find links to article

immunity. In 2007, the first experimental evidence that CRISPR was an adaptive immune system was published. A CRISPR region in Streptococcus thermophilus acquired

Toll-like receptor 4 (9,110 words) [view diff] exact match in snippet view article find links to article

cytokine storms. The impact of TLR4 activation on the innate and adaptive immune system explains why TLR4 agonists, such as LPS derivatives, have been developed

Arsenic biochemistry (5,517 words) [view diff] exact match in snippet view article find links to article

repair proteins. Arsenic is highly detrimental to the innate and the adaptive immune system of the body. When the amount of unfolded and misfolded proteins

CGAS–STING cytosolic DNA sensing pathway (2,886 words) [view diff] exact match in snippet view article find links to article

dendritic cells (DCs). DCs link the innate immune system with the adaptive immune system through phagocytosis and MHC presentation of foreign antigen. The

Non-specific effect of vaccines (6,105 words) [view diff] exact match in snippet view article find links to article

pathogens (trained innate immunity). In SCID mice that have no adaptive immune system, BCG reduced mortality from an otherwise lethal candida infection

CRISPR-Display (2,133 words) [view diff] exact match in snippet view article find links to article

of Technology (MIT), USA. The CRISPR/Cas9 system is based on an adaptive immune system of prokaryotic organisms, and its use for genome editing was first

Ozone (18,196 words) [view diff] exact match in snippet view article find links to article

ability to clear bacteria appears impaired by exposure to ozone. The adaptive immune system is the branch of immunity that provides long-term protection via

Intelligent design (19,821 words) [view diff] exact match in snippet view article find links to article

flagellum of E. coli, the blood clotting cascade, cilia, and the adaptive immune system. Critics point out that the irreducible complexity argument assumes

Eftilagimod alpha (2,722 words) [view diff] exact match in snippet view article find links to article

with INSERM and Merck Serono, to elucidate LAG-3’s role in the adaptive immune system. Triebel et al. had successfully produced a soluble LAG-3Ig fusion

Proteasome (15,662 words) [view diff] exact match in snippet view article find links to article

plays a straightforward but critical role in the function of the adaptive immune system. Peptide antigens are displayed by the major histocompatibility

Animal testing (21,848 words) [view diff] exact match in snippet view article find links to article

large numbers may be housed and studied. However, the lack of an adaptive immune system and their simple organs prevent worms from being used in several

Ronald J. Falk (3,189 words) [view diff] exact match in snippet view article find links to article

observations reveal interactions between restricted MPO epitopes and the adaptive immune system within ANCA vasculitis that may inform new antigen-specific therapies

Autism therapies (18,922 words) [view diff] exact match in snippet view article find links to article

promise as treatment for the disorder. Changes in the innate and adaptive immune system have been observed- those with autism show an imbalance in CD3+

Moriya Tsuji (2,096 words) [view diff] exact match in snippet view article find links to article

2011). "A mechanism for glycoconjugate vaccine activation of the adaptive immune system and its implications for vaccine design". Nature Medicine. 17 (12):

Off-target genome editing (7,115 words) [view diff] exact match in snippet view article find links to article

increasingly precise and predictable. The CRISPR-Cas9 system works as the adaptive immune system in bacteria and archaea. When a virus infects the bacteria, this

Manyuan Long (2,802 words) [view diff] case mismatch in snippet view article find links to article

Dating Reveals an Early and Rapid Evolutionary Construction of the Adaptive Immune System". Genome Biology and Evolution. 15 (5). doi:10.1093/gbe/evad081

Genome-wide CRISPR-Cas9 knockout screens (6,172 words) [view diff] exact match in snippet view article find links to article

[citation needed] Since initial identification as a prokaryotic adaptive immune system, the bacterial type II clustered regularly interspaced short palindrome

De novo gene birth (13,540 words) [view diff] exact match in snippet view article find links to article

PMID 30065088. Bekpen C, Xie C, Tautz D (August 2018). "Dealing with the adaptive immune system during de novo evolution of genes from intergenic sequences". BMC