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Find link is a tool written by Edward Betts.Longer titles found: Dopaminergic cell groups (view), Dopaminergic pathways (view), Retracted article on dopaminergic neurotoxicity of MDMA (view), List of dopaminergic drugs (view)
searching for Dopaminergic 301 found (1104 total)
alternate case: dopaminergic
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function in energy homeostasis, ghrelin also activates the cholinergic–dopaminergic reward link in inputs to the ventral tegmental area and in the mesolimbicPars compacta (975 words) [view diff] exact match in snippet view article find links to article
reticulata); it is situated medial to the pars reticulata. It is formed by dopaminergic neurons. It projects to the striatum and portions of the cerebral cortexQuinpirole (445 words) [view diff] exact match in snippet view article find links to article
in primary neuronal cultures it also reduces the rate of firing in dopaminergic neurons. Quinelorane Eilam D, Szechtman H (February 1989). "BiphasicPropylnorapomorphine (428 words) [view diff] exact match in snippet view article find links to article
receptors, the latter of which overcomes the former to increase postsynaptic dopaminergic signaling only with high doses. Apomorphine "(6aS)-6-Propyl-5,6,6aProgesterone receptor (2,847 words) [view diff] exact match in snippet view article find links to article
(mPFC) of the mesocortical dopaminergic pathway. PR activity during this time period impacts the development of dopaminergic innervation of the mPFC fromSympathomimetic drug (891 words) [view diff] exact match in snippet view article find links to article
receptor), such as α-adrenergic agonists, β-adrenergic agonists, and dopaminergic agonists; or indirect-acting (interaction not between drug and receptor)UH-232 (501 words) [view diff] exact match in snippet view article find links to article
agonist at the D3 subtype, and an antagonist at D2Sh autoreceptors on dopaminergic nerve terminals. It causes dopamine release in the brain and has a stimulantDopamine dysregulation syndrome (1,536 words) [view diff] exact match in snippet view article find links to article
dysfunction of the reward system observed in some individuals taking dopaminergic medications for an extended length of time. It typically occurs in peopleNeurotoxicity (2,249 words) [view diff] exact match in snippet view article find links to article
(DOPAL), is a potent inducer of programmed cell death (apoptosis) in dopaminergic neurons. DOPAL may play an important role in the pathology of Parkinson'sMidbrain tegmentum (552 words) [view diff] exact match in snippet view article find links to article
and learning. The midbrain tegmentum is also an important part of the dopaminergic system which is essential for feelings of reward and pleasure. Two regionsCHRNA6 (956 words) [view diff] exact match in snippet view article find links to article
|alt=Nicotine Activity on Dopaminergic Neurons edit]] The interactive pathway map can be edited at WikiPathways: "NicotineDopaminergic_WP1602". Nicotinic acetylcholinePHA-543,613 (471 words) [view diff] exact match in snippet view article find links to article
deficits in schizophrenia. It reduces excitotoxicity and protects striatal dopaminergic neurons in rat models. It also potentiates cognitive enhancement fromUltradian rhythm (480 words) [view diff] exact match in snippet view article find links to article
lasting approximately 4 hours were attributed to the dopaminergic system in mammals. When the dopaminergic system is perturbed either by use of drugs or byPersonism (742 words) [view diff] exact match in snippet view article find links to article
required to achieve acceptable behavior, but a digital limbic system and a dopaminergic pathways alternative, would deliver a more acceptable result for futureEmedastine (463 words) [view diff] exact match in snippet view article find links to article
relieved. Emedastine appears to be devoid of effects on adrenergic, dopaminergic and serotonin receptors. This drug was developed by Alcon, which is globalPersonism (742 words) [view diff] exact match in snippet view article find links to article
required to achieve acceptable behavior, but a digital limbic system and a dopaminergic pathways alternative, would deliver a more acceptable result for future6-Br-APB (299 words) [view diff] exact match in snippet view article find links to article
self-administration in animals, with a similar but not identical profile to that of dopaminergic stimulants such as amphetamine. Neumeyer JL, et al. (December 1991).Rett syndrome (6,288 words) [view diff] exact match in snippet view article find links to article
caudate-putamen, the principal target of dopaminergic neurons arising from the SNpc. Moreover, a neurochemical analysis of dopaminergic contents in microdissected midbrainMotivational salience (3,234 words) [view diff] exact match in snippet view article find links to article
neurotransmission in the mesocorticolimbic projection, but activity in other dopaminergic pathways and hedonic hotspots (e.g., the ventral pallidum) also modulateGBR-12935 (370 words) [view diff] exact match in snippet view article find links to article
3H radiolabelled form for the purpose of mapping the distribution of dopaminergic neurons in the brain by selective labelling of dopamine transporter proteinsDimethocaine (1,530 words) [view diff] exact match in snippet view article find links to article
found to be a mixture of caffeine and lidocaine, and the lack of any dopaminergic stimulant ingredient in such mixes may explain the limited recreationalGlial cell line-derived neurotrophic factor (2,730 words) [view diff] exact match in snippet view article find links to article
this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neuronsGYKI 52895 (259 words) [view diff] exact match in snippet view article find links to article
methylphenidate and its derivatives (e.g. ethylphenidate). However, dopaminergic drugs are also prone to producing emetic effects such as in the caseTemgicoluril (751 words) [view diff] exact match in snippet view article find links to article
norepinephrine levels and increases brain serotonin levels without modulating dopaminergic systems or cholinergic systems. Temgicoluril purportedly has anti-anxietyEPPTB (276 words) [view diff] exact match in snippet view article find links to article
been used to demonstrate an important role for TAAR1 in regulation of dopaminergic signalling in the limbic system. Although EPPTB has high affinity forRestless legs syndrome (8,312 words) [view diff] exact match in snippet view article find links to article
Romero S, Cano-Pumarega I, García-Borreguero D (2019). "Non-dopaminergic vs. dopaminergic treatment options in restless legs syndrome". Pharmacology of6-Chloro-5-ethoxy-N-(pyridin-2-yl)indoline-1-carboxamide (109 words) [view diff] exact match in snippet view article
5-HT2C-mediated disinhibition of dopamine release can cause interactions with dopaminergic drugs. RS-102,221 SB-242,084 SCQ1 McCorvy JD, Harland AA, MaglathlinSerotonergic cell groups (575 words) [view diff] no match in snippet view article find links to article
Serotonergic cell groups refer to collections of neurons in the central nervous system that have been demonstrated by histochemical fluorescence to containCHRNB2 (1,073 words) [view diff] exact match in snippet view article find links to article
|alt=Nicotine Activity on Dopaminergic Neurons edit]] The interactive pathway map can be edited at WikiPathways: "NicotineDopaminergic_WP1602". Nicotinic acetylcholineTebufenpyrad (779 words) [view diff] exact match in snippet view article find links to article
been shown to affect the dopaminergic neuronal cell lines N27 by disrupting the mitochondrial dynamics. Loss of dopaminergic cells have been linked toOSU-6162 (900 words) [view diff] exact match in snippet view article find links to article
subhuman primates: evidence for tone-dependent normalization of striatal dopaminergic activity". Synapse. 28 (4): 280–7. doi:10.1002/(SICI)1098-2396(19980Amperozide (417 words) [view diff] exact match in snippet view article find links to article
but does inhibit dopamine release, and alters the firing pattern of dopaminergic neurons. It was investigated for the treatment of schizophrenia in humansAthetosis (2,645 words) [view diff] exact match in snippet view article find links to article
extracellular dopamine levels and therefore, an increase in the activity of the dopaminergic neurons. Furthermore, this increase in extracellular concentration is3,4-Dihydroxyphenylacetaldehyde (253 words) [view diff] exact match in snippet view article find links to article
associated with mitochondrial abnormalities and neurotoxicity by way of dopaminergic compounds, while reducing the emphasis on other dopamine derivativesΒ-Hexachlorocyclohexane (415 words) [view diff] exact match in snippet view article find links to article
beta-HCH, are neurotoxic, cause oxidative stress, and damage the brain's dopaminergic system. Human studies show that exposure to beta-HCH is linked to Parkinson's3-Methylmethcathinone (1,691 words) [view diff] exact match in snippet view article find links to article
potently inhibits norepinephrine uptake and displays more pronounced dopaminergic vs. serotonergic activity. 3-MMC was first encountered in Sweden in 2012Reticuline (346 words) [view diff] exact match in snippet view article find links to article
precursor of morphine and many other alkaloids. It is also toxic to dopaminergic neurons causing a form of atypical parkinsonism known as GuadeloupeanCypermethrin (1,253 words) [view diff] exact match in snippet view article find links to article
found to induce dopaminergic neurodegeneration in rats, and postnatal exposure enhances the susceptibility of animals to dopaminergic neurodegenerationExtrapyramidal symptoms (1,359 words) [view diff] exact match in snippet view article find links to article
5-HT2A receptor affinity which lead to lower rates of EPS. Other anti-dopaminergic drugs, like the antiemetic metoclopramide, can also result in extrapyramidalRelated to receptor tyrosine kinase (893 words) [view diff] exact match in snippet view article find links to article
guidance Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation midbrain dopaminergic neuron differentiation planar cell polarity pathwayHallucination (6,892 words) [view diff] exact match in snippet view article find links to article
the person maintains an awareness that they are hallucinating, unlike dopaminergic hallucinations. Hallucinations are associated with structural and functionalNeurotensin (1,815 words) [view diff] exact match in snippet view article find links to article
hormone and prolactin release and has significant interaction with the dopaminergic system. Neurotensin was first isolated from extracts of bovine hypothalamusManagement of Parkinson's disease (8,447 words) [view diff] exact match in snippet view article find links to article
management of symptoms and side effects resulting from enhancement of dopaminergic function. The start of L-DOPA treatment may be delayed by using otherBiological basis of love (3,160 words) [view diff] exact match in snippet view article find links to article
tyramine) play a critical role in regulating neuronal activity in the dopaminergic pathways of the central nervous system. Testosterone and estrogen contributeVPS35 (4,050 words) [view diff] exact match in snippet view article find links to article
second most common neurodegenerative disease. It is characterized by dopaminergic neuron loss in the substantia nigra pars compacta and the toxic aggregationRTI-55 (983 words) [view diff] exact match in snippet view article find links to article
WIN35428 > RTI-31 > RTI-51. In contrast to RTI-31 which is predominantly dopaminergic, increasing the size of the covalently bonded halogen from a chlorinePITX3 (661 words) [view diff] exact match in snippet view article find links to article
Smits SM, Smidt MP (2006). "The role of Pitx3 in survival of midbrain dopaminergic neurons". Parkinson's Disease and Related Disorders. Journal of NeuralPolypyrimidine tract-binding protein (237 words) [view diff] exact match in snippet view article find links to article
mice models of Parkinson's disease in order to convert astrocytes to dopaminergic neurons and as a consequence restore motor function in these mice. PolypyrimidineVesicular monoamine transporter 2 (2,015 words) [view diff] exact match in snippet view article find links to article
PMID 12827358. S2CID 20764857. Tritsch NX, Ding JB, Sabatini BL (2012). "Dopaminergic neurons inhibit striatal output through non-canonical release of GABA"Cyclin-dependent kinase 5 (5,356 words) [view diff] exact match in snippet view article find links to article
|alt=Nicotine Activity on Dopaminergic Neurons edit]] The interactive pathway map can be edited at WikiPathways: "NicotineDopaminergic_WP1602". Cyclin-dependentParkinsonian gait (4,424 words) [view diff] exact match in snippet view article find links to article
with dopaminergic medication, perhaps pointing to a common underlying pathophysiology. It is possible to demonstrate poor and paradoxical dopaminergic medicationVesicular monoamine transporter 2 (2,015 words) [view diff] exact match in snippet view article find links to article
PMID 12827358. S2CID 20764857. Tritsch NX, Ding JB, Sabatini BL (2012). "Dopaminergic neurons inhibit striatal output through non-canonical release of GABA"Cyclin-dependent kinase 5 (5,356 words) [view diff] exact match in snippet view article find links to article
|alt=Nicotine Activity on Dopaminergic Neurons edit]] The interactive pathway map can be edited at WikiPathways: "NicotineDopaminergic_WP1602". Cyclin-dependent25B-NBOMe (3,153 words) [view diff] exact match in snippet view article find links to article
Custodio et al. (2019) evaluated the potential involvement of dysregulated dopaminergic system, neuroadaptation, and brain wave changes which may contributeMedium spiny neuron (4,043 words) [view diff] exact match in snippet view article find links to article
neuroscience.2015.06.033. PMC 4523218. PMID 26116518. [The striatum] receives dopaminergic inputs from the ventral tegmental area (VTA) and the substantia nigraDopamine transporter (4,635 words) [view diff] exact match in snippet view article find links to article
distribution of DAT has been found in areas of the brain with established dopaminergic circuitry, including the nigrostriatal, mesolimbic, and mesocorticalLenticular fasciculus (106 words) [view diff] exact match in snippet view article find links to article
Lenticular fasciculus The image shows dopaminergic pathways of the human brain in normal condition (left) and Parkinsons Disease (right). Red Arrows indicateGlutamate hypothesis of schizophrenia (3,902 words) [view diff] exact match in snippet view article find links to article
combined with a GABAA activating drug.[dubious – discuss] Likely, both dopaminergic and glutaminergic abnormalities are implicated in schizophrenia, from9-Methyl-β-carboline (553 words) [view diff] exact match in snippet view article find links to article
of primary mesencephalic dopaminergic neuron cell cultures, the substance increased the number of differentiated dopaminergic neurons and produced higherDopamine receptor D1 (3,089 words) [view diff] exact match in snippet view article find links to article
receptors (azodopa) has been described that allows reversible control of dopaminergic transmission in wildtype animals. Many typical and atypical antipsychoticsLMX1A (652 words) [view diff] exact match in snippet view article find links to article
hippocampus development regulation of cell growth brain development dopaminergic neuron differentiation regulation of gene expression positive regulationKenneth Blum (1,981 words) [view diff] exact match in snippet view article find links to article
induce dopamine homeostasis and is best described as a glutaminergic-dopaminergic optimization complex. There are over 30 clinical trials for a numberProto-oncogene Wnt-1 (1,008 words) [view diff] exact match in snippet view article find links to article
astrocyte-dopaminergic neuron signaling positive regulation of canonical Wnt signaling pathway Wnt signaling pathway involved in midbrain dopaminergic neuronTetrahydroisoquinoline (990 words) [view diff] exact match in snippet view article find links to article
"Isoquinolines, beta-carbolines and alcohol drinking: involvement of opioid and dopaminergic mechanisms". Experientia. 45 (5): 436–443. doi:10.1007/BF01952025. PMID 2656285Examples of in vitro transdifferentiation by lineage-instructive approach (1,129 words) [view diff] exact match in snippet view article find links to article
Brn2) Fibroblasts → dopaminergic neurons (Ascl1, Brn2, Myt1l, Lmx1a, and FoxA2) or (Ascl1, Nurr1, and Lmx1a) Astrocytes → dopaminergic neurons (Ascl1, Lmx1bDaT scan (556 words) [view diff] exact match in snippet view article find links to article
method, based on SPECT imaging, to investigate if there is a loss of dopaminergic neurons in striatum. The term may also refer to a brand name of IoflupaneLRP6 (1,411 words) [view diff] exact match in snippet view article find links to article
in somitogenesis cerebellum morphogenesis roof of mouth development dopaminergic neuron differentiation positive regulation of Wnt signaling pathway involvedCHRNA4 (1,178 words) [view diff] exact match in snippet view article find links to article
|alt=Nicotine Activity on Dopaminergic Neurons edit]] The interactive pathway map can be edited at WikiPathways: "NicotineDopaminergic_WP1602". Nicotinic acetylcholineIsotretinoin (7,349 words) [view diff] exact match in snippet view article find links to article
including isotretinoin, bind to dopaminergic receptors in the central nervous system. Isotretinoin may affect dopaminergic neurotransmission by disruptingGlobus pallidus (1,303 words) [view diff] exact match in snippet view article find links to article
than 90% of synapses.[citation needed] The two pallidal nuclei receive dopaminergic axons from the pars compacta of the substantia nigra. This area of theBehavioral addiction (2,888 words) [view diff] exact match in snippet view article find links to article
emotional significance and associated learning. Research shows that dopaminergic projections from the ventral tegmental area facilitate a motivationalPVLV (109 words) [view diff] exact match in snippet view article find links to article
behavioral and neural data on Pavlovian conditioning and the midbrain dopaminergic neurons that fire in proportion to unexpected rewards. It is an alternativeGNAI1 (1,434 words) [view diff] exact match in snippet view article find links to article
|alt=Nicotine Activity on Dopaminergic Neurons edit]] The interactive pathway map can be edited at WikiPathways: "NicotineDopaminergic_WP1602". GNAI1 has beenKCNK3 (1,048 words) [view diff] exact match in snippet view article find links to article
|alt=Nicotine Activity on Dopaminergic Neurons edit]] The interactive pathway map can be edited at WikiPathways: "NicotineDopaminergic_WP1602". KCNK3 has beenSH-SY5Y (1,387 words) [view diff] exact match in snippet view article find links to article
and differentiation. They are adrenergic in phenotype but also express dopaminergic markers and, as such, have been used to study Parkinson's disease, neurogenesisLisdexamfetamine (10,355 words) [view diff] exact match in snippet view article find links to article
release of dopamine in the central nervous system. Amphetamine and other dopaminergic drugs also increase power output at fixed levels of perceived exertionAnsa lenticularis (94 words) [view diff] exact match in snippet view article find links to article
Ansa lenticularis The image shows dopaminergic pathways of the human brain in normal condition (left) and Parkinsons Disease (right). Red Arrows indicateThalamic fasciculus (153 words) [view diff] exact match in snippet view article find links to article
Thalamic fasciculus The image shows dopaminergic pathways of the human brain in normal condition (left) and Parkinsons Disease (right). Red Arrows indicateN,N-Dimethyldopamine (1,653 words) [view diff] exact match in snippet view article find links to article
(1975). "Cholinergic effects of molecular segments of apomorphine and dopaminergic effects of N,N-dialkylated dopamines." J. Med. Chem. 18 1194-1200. RD. James Surmeier (2,529 words) [view diff] exact match in snippet view article find links to article
despite widespread consensus regarding the clinical relevance of striatal dopaminergic signaling, the distribution and segregation of different classes of dopamineGDNF family of ligands (1,125 words) [view diff] exact match in snippet view article find links to article
migration. In particular signalling by GDNF promotes the survival of dopaminergic neurons. At the cell surface of target cells, a signalling complex formsPEPAP (388 words) [view diff] exact match in snippet view article find links to article
N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine structure were active as dopaminergic neurotoxins. Most structural changes, including replacing the N-methylGDNF family of ligands (1,125 words) [view diff] exact match in snippet view article find links to article
migration. In particular signalling by GDNF promotes the survival of dopaminergic neurons. At the cell surface of target cells, a signalling complex formsPEPAP (388 words) [view diff] exact match in snippet view article find links to article
N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine structure were active as dopaminergic neurotoxins. Most structural changes, including replacing the N-methylETS transcription factor family (1,020 words) [view diff] exact match in snippet view article find links to article
to be important players in the specification and differentiation of dopaminergic neurons in both C. elegans and olfactory bulbs of mice. Amongst membersTranscranial direct stimulation in Parkinson's disease gait rehabilitation (2,753 words) [view diff] exact match in snippet view article find links to article
as it is independent of the walking speed. During the ON phase of the Dopaminergic treatment there is increase in gait speed and step length. Cadence andAporphine (2,203 words) [view diff] exact match in snippet view article find links to article
(S)-(+)-N-Propylnorapomorphine is highly selective for meso-limbic dopaminergic tracts and function as efficacious partial agonists, with no elevationLomerizine (1,470 words) [view diff] exact match in snippet view article find links to article
While some calcium-channel blockers, such as flunarizine, act on the dopaminergic system, lomerizine is ineffective in vivo at inhibiting the release ofTenilapine (156 words) [view diff] exact match in snippet view article find links to article
E, Di Matteo V (2011). "The 5-HT2C Receptor Subtype Controls Central Dopaminergic Systems: Evidence from Electrophysiological and Neurochemical Studies"Heterosynaptic plasticity (1,640 words) [view diff] exact match in snippet view article find links to article
memories in mammals, while serotonin's occurs in invertebrates. Within dopaminergic and GABAergic terminals, the neuromodulator dopamine is released viaVAMP1 (895 words) [view diff] exact match in snippet view article find links to article
|alt=Nicotine Activity on Dopaminergic Neurons edit]] The interactive pathway map can be edited at WikiPathways: "NicotineDopaminergic_WP1602". GRCh38: EnsemblGNG2 (1,092 words) [view diff] exact match in snippet view article find links to article
|alt=Nicotine Activity on Dopaminergic Neurons edit]] The interactive pathway map can be edited at WikiPathways: "NicotineDopaminergic_WP1602". GRCh38: EnsemblArea postrema (3,006 words) [view diff] exact match in snippet view article find links to article
vomiting by the ferrets. Yet a pre-treatment with 6-hydroxydopamine, a dopaminergic neurotoxin, significantly reduced the number of emetic episodes in thePutamen (3,308 words) [view diff] exact match in snippet view article find links to article
the amount of dopamine binding to post synaptic terminals, presynaptic dopaminergic neurons function to reuptake the excess dopamine. The putamen also playsMichael Hausser (468 words) [view diff] exact match in snippet view article find links to article
Häusser, M. A.; Jack, J. J. (1991). "Electrophysiology of dopaminergic and non-dopaminergic neurones of the guinea-pig substantia nigra pars compactaCauses of Parkinson's disease (3,255 words) [view diff] exact match in snippet view article find links to article
Parkinson's disease (PD) is primarily caused by the gradual degeneration of dopaminergic neurons in the region known as the substantia nigra along with otherDeoxyepinephrine (1,372 words) [view diff] exact match in snippet view article find links to article
Pharmacol. 107 303–310. A. Daul et al. (1995). "Dose-dependent separation of dopaminergic and adrenergic effects of epinine in healthy volunteers." Naunyn-SchmiedebergsTemperament and Character Inventory (1,676 words) [view diff] exact match in snippet view article find links to article
harm avoidance, and reward dependence, was correlated with low basal dopaminergic activity, high serotonergic activity, and low basal noradrenergic activityMir-7 microRNA precursor (1,373 words) [view diff] exact match in snippet view article find links to article
miRNA-7a mediated gene silencing, which is necessary to control the rate of dopaminergic neuron production in the olfactory bulb. Multiple roles and targets ofCHRNA3 (1,040 words) [view diff] exact match in snippet view article find links to article
[[ ]] [[ ]] [[ ]] [[ ]] [[ ]] [[ ]] [[ ]] [[ ]] |alt=Nicotine Activity on Dopaminergic Neurons edit]] Nicotine Activity on Dopaminergic Neurons editHolmes tremor (1,175 words) [view diff] exact match in snippet view article find links to article
characteristics of the tremor. Because the disease is involved with the dopaminergic system, most treatments involve levodopa. Drugs used to treat other typesAmmTX3 (823 words) [view diff] exact match in snippet view article find links to article
increases spontaneous pacemaking frequency in substantia nigra pars compacta dopaminergic neurons The Ki of AmmTX3 was found to be approximately 131 nM when testedHP-505 (289 words) [view diff] exact match in snippet view article find links to article
"Spiroisobenzofuran Piperidine Derivatives. Interaction with Pre- and Post-Synaptic Dopaminergic Sites". In Usdin E, Kopin IJ, Barchas J (eds.). Catecholamines: BasicPituitary pars intermedia dysfunction (2,770 words) [view diff] exact match in snippet view article find links to article
"Nitration and increased alpha-synuclein expression associated with dopaminergic neurodegeneration in equine pituitary pars intermedia dysfunction". JournalAmy Hauck Newman (357 words) [view diff] exact match in snippet view article find links to article
substance use disorders, with an emphasis on selective ligands for the dopaminergic system. Newman completed a B.S. in chemistry at the Mary Washington CollegePsychosis (14,902 words) [view diff] exact match in snippet view article find links to article
hypothesis' may be oversimplified. Soyka and colleagues found no evidence of dopaminergic dysfunction in people with alcohol-induced psychosis and Zoldan et alPallidothalamic tracts (273 words) [view diff] exact match in snippet view article find links to article
Pallidothalamic tracts The image shows dopaminergic pathways of the human brain in normal condition (left) and Parkinsons Disease (right). Red Arrows indicateCatechol-O-methyltransferase (3,206 words) [view diff] exact match in snippet view article find links to article
dopamine levels following neurotransmitter release, ultimately increasing dopaminergic stimulation of the postsynaptic neuron. Given the preferential role ofHypofrontality (2,404 words) [view diff] exact match in snippet view article find links to article
linked to an increase in norepinephrine transmission and decrease in dopaminergic transmission with reduced dopamine efflux in the frontal cortex. OthersMania (5,447 words) [view diff] exact match in snippet view article find links to article
risk of switching while on an antidepressant is between 6-69 percent. Dopaminergic drugs such as reuptake inhibitors and dopamine agonists may also increaseDopamine receptor D3 (3,175 words) [view diff] exact match in snippet view article find links to article
Hamperl K, Hübner H, Gmeiner P (November 2008). "Novel D3 selective dopaminergics incorporating enyne units as nonaromatic catechol bioisosteres: synthesisArcuate nucleus (1,776 words) [view diff] exact match in snippet view article find links to article
manner to decrease its levels by stimulating the release of dopamine. Dopaminergic neurons of the arcuate also inhibit the release of gonadotropin-releasingMonoamine oxidase B (4,091 words) [view diff] exact match in snippet view article find links to article
reaction"). MAO-A also exists in catecholaminergic neurons, such as dopaminergic neurons in SN, norepinephrine neurons in locus coeruleus, etc. [18].Electroretinography (1,249 words) [view diff] exact match in snippet view article find links to article
treatment modalities. A 2013 study by Nasser et al. found that the retinal dopaminergic response to eating a brownie is equivalent in magnitude to the responseTardive psychosis (492 words) [view diff] exact match in snippet view article find links to article
needed] In addition to dopaminergic upregulation in the nigrostriatal tracts, many investigators have suggested that dopaminergic upregulation may occurStimulant psychosis (2,352 words) [view diff] exact match in snippet view article find links to article
"Isopropylphenidate: An ester homolog of methylphenidate with sustained and selective dopaminergic activity and reduced drug interaction liability". Journal of Child andNancy Zahniser (1,187 words) [view diff] exact match in snippet view article find links to article
American pharmacologist, best known for her work involving the mechanism of dopaminergic pathways and chemical modifications of them. Although born in Ann ArborTardive psychosis (492 words) [view diff] exact match in snippet view article find links to article
needed] In addition to dopaminergic upregulation in the nigrostriatal tracts, many investigators have suggested that dopaminergic upregulation may occurBiogenesis of lysosome-related organelles complex 1 (1,679 words) [view diff] exact match in snippet view article find links to article
not the D1 receptor. BLOC-1 mutations in dysbindin therefore can alter dopaminergic signaling in the brain which may confer symptoms of schizophrenia. TheseIvar Mendez (3,067 words) [view diff] exact match in snippet view article find links to article
Hong M, Miles GB, et al. (August 2008). "A multitarget basal ganglia dopaminergic and GABAergic transplantation strategy enhances behavioural recoveryOR5T1 (225 words) [view diff] exact match in snippet view article find links to article
smell signal transduction response to stimulus synaptic transmission, dopaminergic negative regulation of adenylate cyclase activity adenylate cyclase-inhibitingOR56A1 (223 words) [view diff] exact match in snippet view article find links to article
smell signal transduction response to stimulus synaptic transmission, dopaminergic negative regulation of adenylate cyclase activity adenylate cyclase-inhibitingPsychological dependence (2,177 words) [view diff] exact match in snippet view article find links to article
regulation of α6β2*n-icotinic acetylcholine receptors in the mesostriatal dopaminergic pathways. A study examined how rats experienced morphine withdrawal inPhenethylamine (4,237 words) [view diff] exact match in snippet view article find links to article
receptor 1 in the functional regulation of monoamine transporters and dopaminergic activity". Journal of Neurochemistry. 116 (2): 164–176. doi:10.1111/jProtein Wnt-5a (3,402 words) [view diff] exact match in snippet view article find links to article
planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation midbrain dopaminergic neuron differentiation neuron differentiationOR13F1 (271 words) [view diff] exact match in snippet view article find links to article
smell signal transduction response to stimulus synaptic transmission, dopaminergic negative regulation of adenylate cyclase activity adenylate cyclase-inhibitingGNB1 (1,276 words) [view diff] exact match in snippet view article find links to article
|alt=Nicotine Activity on Dopaminergic Neurons edit]] The interactive pathway map can be edited at WikiPathways: "NicotineDopaminergic_WP1602". GNB1 has beenLateral hypothalamus (3,032 words) [view diff] exact match in snippet view article find links to article
pedunculopontine nucleus and laterodorsal tegmental nucleus. The histaminergic, dopaminergic, serotonergic, noradrenergic, and cholinergic nuclei which the lateralTAAR1 (6,646 words) [view diff] exact match in snippet view article find links to article
reduce the firing rate of dopamine neurons, in turn preventing a hyper-dopaminergic state. Amphetamine and trace amines can enter the presynaptic neuronAnimal model of schizophrenia (2,793 words) [view diff] exact match in snippet view article find links to article
There is evidence for increased activity of the mesolimbic pathway, a dopaminergic pathway, in schizophrenia patients. This comes from the discovery ofQuinelorane (165 words) [view diff] exact match in snippet view article find links to article
PMID 11923462. Gasior M, Paronis CA, Bergman J (January 2004). "Modification by dopaminergic drugs of choice behavior under concurrent schedules of intravenous salineNeurotransmission (2,477 words) [view diff] exact match in snippet view article find links to article
glutamatergic excitatory and GABAergic inhibitory synaptic inputs into the dopaminergic neurons of the VTA and the glutamate transmission in the NAc. Thus, theKCNK9 (1,559 words) [view diff] exact match in snippet view article find links to article
|alt=Nicotine Activity on Dopaminergic Neurons edit]] The interactive pathway map can be edited at WikiPathways: "NicotineDopaminergic_WP1602". Tandem poreHyperosmia (651 words) [view diff] exact match in snippet view article find links to article
hydrocarbons can cause hyperosmia, most likely due to the destruction of dopaminergic neurons in the olfactory bulb. Methotrexate, administered in the treatmentMesostriatal system (323 words) [view diff] exact match in snippet view article find links to article
mesostriatal nuclei have been performed, revealing that the midbrain dopaminergic nuclei receive projections from the pedunculopontine tegmentum and laterodorsalNeurturin (1,477 words) [view diff] exact match in snippet view article find links to article
potent effects on survival and function of developing and mature midbrain dopaminergic neurons (DA) in vitro. In vivo the direct administration of neurturinTridimensional Personality Questionnaire (341 words) [view diff] exact match in snippet view article find links to article
harm avoidance, and reward dependence, were correlated with low basal dopaminergic activity, high serotonergic activity, and low basal noradrenergic activityClozapine N-oxide (463 words) [view diff] exact match in snippet view article find links to article
clozapine. Clozapine can bind to a number of different serotonergic, dopaminergic and adrenergic receptors within the brain. Therefore, behavioural dataNational Institute on Drug Abuse (4,577 words) [view diff] exact match in snippet view article find links to article
touted as proving that MDMA (ecstasy) caused dopaminergic neurotoxicity in monkeys. His paper "Severe Dopaminergic Neurotoxicity in Primates After a CommonNeuropsychopharmacology (4,261 words) [view diff] exact match in snippet view article find links to article
5HT2A activity has a net pro-dopaminergic effect, whereas 5HT2C receptor agonism has an inhibitory effect on dopaminergic activity, particularly in theRMST (gene) (254 words) [view diff] exact match in snippet view article
the brain, RMST is expressed in the developing ventral midbrain where dopaminergic neurons are formed, the developing isthmus and in the dorsal midlineBrain mitochondrial carrier protein 1 (1,733 words) [view diff] exact match in snippet view article find links to article
accompanied by Parkinson's. This symptom occurs because of the loss of dopaminergic neurons during the elimination of dopamine neurotransmitters. BecausePathophysiology of Parkinson's disease (2,216 words) [view diff] exact match in snippet view article find links to article
The pathophysiology of Parkinson's disease is death of dopaminergic neurons as a result of changes in biological activity in the brain with respect toTrepipam (120 words) [view diff] exact match in snippet view article find links to article
Vargas R, Winnberg E, Martínez A (December 2020). "New information of dopaminergic agents based on quantum chemistry calculations". Sci Rep. 10 (1): 21581Johan Giesecke (289 words) [view diff] exact match in snippet view article find links to article
in Stockholm. He defended his thesis, On The Molecular Structure Of Dopaminergic Substances, at the Karolinska Institute. He trained as an infectiousOR56A4 (318 words) [view diff] exact match in snippet view article find links to article
smell signal transduction response to stimulus synaptic transmission, dopaminergic negative regulation of adenylate cyclase activity adenylate cyclase-inhibitingMesocarb (1,196 words) [view diff] exact match in snippet view article find links to article
"Characterization of pharmacological and wake-promoting properties of the dopaminergic stimulant sydnocarb in rats". The Journal of Pharmacology and ExperimentalCentral nervous system fatigue (4,122 words) [view diff] exact match in snippet view article find links to article
the VTA is an area dense in dopaminergic neurons that project to many areas of the brain, this suggests that dopaminergic neurotransmission drives physicalCentral nervous system fatigue (4,122 words) [view diff] exact match in snippet view article find links to article
the VTA is an area dense in dopaminergic neurons that project to many areas of the brain, this suggests that dopaminergic neurotransmission drives physicalPerirhinal cortex (945 words) [view diff] exact match in snippet view article find links to article
with a specific source. The perirhinal cortex also receives a large dopaminergic input and signals the rewards that are associated with visual stimuliTime perception (10,059 words) [view diff] exact match in snippet view article find links to article
variety of age-related changes in the aging brain, such as the lowering in dopaminergic levels with older age; however, the details are still being debated.Stimulant (13,076 words) [view diff] exact match in snippet view article find links to article
methamphetamine produces similar effects as well as marked degeneration of dopaminergic neurons, resulting in an increased risk for Parkinson's disease. StimulantsABT-724 (358 words) [view diff] exact match in snippet view article find links to article
2-(4-pyridin-2-ylpiperazin-1-ylmethyl)-1H-benzimidazole (ABT-724), a dopaminergic agent with a novel mode of action for the potential treatment of erectileIsopropylphenidate (205 words) [view diff] exact match in snippet view article find links to article
"Isopropylphenidate: an ester homolog of methylphenidate with sustained and selective dopaminergic activity and reduced drug interaction liability" (PDF). Journal of ChildFGF20 (221 words) [view diff] exact match in snippet view article find links to article
expressed in the brain and able to enhance the survival of midbrain dopaminergic neurons in vitro. Kirikoshi H, Sagara N, Saitoh T, Tanaka K, SekiharaWNT2 (976 words) [view diff] exact match in snippet view article find links to article
differentiation midbrain dopaminergic neuron differentiation canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation WntArousal (6,246 words) [view diff] exact match in snippet view article find links to article
in activating the acetylcholine neurons. Another arousal system, the dopaminergic system, releases dopamine produced by the substantia nigra. The neuronsSerotonin (13,723 words) [view diff] exact match in snippet view article find links to article
(fenfluramine, chlorphentermine, and aminorex), and certain anti-Parkinsonian dopaminergic agonists, which also stimulate serotonergic 5-HT2B receptors. These includeGDF5 (1,063 words) [view diff] exact match in snippet view article find links to article
factor 5 on the survival and morphology of embryonic rat midbrain dopaminergic neurones in vitro". J Neurocytol. 33 (5): 479–88. doi:10.1007/s11068-004-0511-yNMDA receptor modulator (496 words) [view diff] exact match in snippet view article find links to article
approved as antipsychotic medications gradually replace the current (dopaminergic) antipsychotics. "Essential Science Indicators". Heresco-Levy, Uriel;Orthodenticle homeobox 2 (2,642 words) [view diff] exact match in snippet view article find links to article
The Otx2 gene is an important transcription factor in the formation of dopaminergic neurons in the Ventral tegmental Area (VTA), an area located in the midbrainNeuroanatomy of intimacy (2,421 words) [view diff] exact match in snippet view article find links to article
ochrogaster) showed that forming a pair bond stimulated the mesolimbic dopaminergic pathway. In this pathway, dopamine is released from the ventral tegmentalWeber's syndrome (263 words) [view diff] exact match in snippet view article find links to article
damaged Effect substantia nigra contralateral parkinsonism because its dopaminergic projections to the basal ganglia innervate the ipsilateral hemisphereWNT9B (444 words) [view diff] exact match in snippet view article find links to article
maintenance midbrain dopaminergic neuron differentiation non-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiationInward-rectifier potassium channel (2,007 words) [view diff] exact match in snippet view article find links to article
FF, Melov S, Di Monte DA, Andersen JK (November 2006). "Nigrostriatal dopaminergic neurodegeneration in the weaver mouse is mediated via neuroinflammationDouglas G. McMahon (2,221 words) [view diff] exact match in snippet view article find links to article
retina involving the melanopsin containing ganglion cells and the retinal dopaminergic amacrine neurons. McMahon earned his Bachelor of Arts in biology fromAnnonacin (863 words) [view diff] exact match in snippet view article find links to article
to cell apoptosis or necrosis. The LC50 of annonacin is 0.018 μM to dopaminergic neurons, and it is the damage done to these neurons that results in theChorea (727 words) [view diff] exact match in snippet view article find links to article
Form Treatment Huntington's-related A common treatment is dopaminergic antagonists, although treatment is largely supportive. Tetrabenazine is the onlyDragana Rogulja (1,872 words) [view diff] exact match in snippet view article find links to article
that as males flies participated in copulations, they had increased dopaminergic activity, and decreased mating driving, highlighting the potential ofEye–hand coordination (2,569 words) [view diff] exact match in snippet view article find links to article
It is a movement disorder and occurs when there is degeneration of dopaminergic neurons that connect the substantia nigra with the caudate nucleus. AManganese (9,502 words) [view diff] exact match in snippet view article find links to article
condition known as manganism, a neurodegenerative disorder that causes dopaminergic neuronal death and symptoms similar to Parkinson's disease. ManganesePiquindone (596 words) [view diff] exact match in snippet view article find links to article
Iwata K (November 1984). "[3H]Ro 22-1319 (piquindone) binds to the D2 dopaminergic receptor subtype in a sodium-dependent manner". Molecular PharmacologyExternal globus pallidus (507 words) [view diff] exact match in snippet view article find links to article
and indirect striatopallidal pathways: Glutamatergic pathways are red, dopaminergic are magenta and GABAergic pathways are blue. STN: Subthalamic NucleusRepinotan (2,572 words) [view diff] exact match in snippet view article find links to article
D4, sigma sites, and 5-HT2C. It is able to increase activity of VTA dopaminergic neurons and medial prefrontal cortex dopamine release. Repinotan actsMedial forebrain bundle (1,156 words) [view diff] exact match in snippet view article find links to article
descending fibers. The mesolimbic pathway, which is a collection of dopaminergic neurons that projects from the ventral tegmental area to the nucleusMedial forebrain bundle (1,156 words) [view diff] exact match in snippet view article find links to article
descending fibers. The mesolimbic pathway, which is a collection of dopaminergic neurons that projects from the ventral tegmental area to the nucleusPersephin (394 words) [view diff] exact match in snippet view article find links to article
the morphological differentiation of cultured ventral mesencephalic dopaminergic neurons". Brain Research Bulletin. 68 (1–2): 42–53. doi:10.1016/j.brainresbullCELSR3 (555 words) [view diff] exact match in snippet view article find links to article
plasma membrane Biological process regulation of protein phosphorylation dopaminergic neuron axon guidance G protein-coupled receptor signaling pathway serotonergicJean-Pierre Changeux (5,468 words) [view diff] exact match in snippet view article find links to article
nicotinic receptors in the basal ganglia and in particular the mesencephalic dopaminergic system. Using mice deleted for nicotinic receptor genes, the group characterisedDihydrotetrabenazine (500 words) [view diff] exact match in snippet view article find links to article
[18F]AV-133 (or [18F]Fluoropropyl-(+)-DTBZ) to identify subjects with dopaminergic degeneration. Nuclear medicine List of PET radiotracers Koeppe, RA; GilmanADCY2 (1,512 words) [view diff] exact match in snippet view article find links to article
|alt=Nicotine Activity on Dopaminergic Neurons edit]] The interactive pathway map can be edited at WikiPathways: "NicotineDopaminergic_WP1602". GRCh38: EnsemblBesonprodil (404 words) [view diff] exact match in snippet view article find links to article
Lévesque D, Rouillard C, Di Paolo T (January 2010). "Effect of non-dopaminergic drug treatment on Levodopa induced dyskinesias in MPTP monkeys: commonProgabide (506 words) [view diff] exact match in snippet view article find links to article
dopamine while reducing striatal cholinergic activity so as to increase dopaminergic effects. Bartholini and colleagues concluded that it was this that causedInterpeduncular nucleus (699 words) [view diff] exact match in snippet view article find links to article
inhibitory influence of habenulointerpeduncular pathways upon cerebral dopaminergic transmission in the rat". Brain Research. 373 (1–2): 324–36. doi:10PPP1CA (1,801 words) [view diff] exact match in snippet view article find links to article
|alt=Nicotine Activity on Dopaminergic Neurons edit]] The interactive pathway map can be edited at WikiPathways: "NicotineDopaminergic_WP1602". PPP1CA has beenOpioid use disorder (12,649 words) [view diff] exact match in snippet view article find links to article
tegmental area control bidirectional reward signalling between dopaminergic and non-dopaminergic neural motivational systems". The European Journal of NeurosciencePersistence (psychology) (2,137 words) [view diff] exact match in snippet view article
subsequently associated with specific neurotransmitter activity, including dopaminergic, serotonergic and noradrenergic systems, whilst there is comparativelyBrain cell (747 words) [view diff] exact match in snippet view article find links to article
may be termed by their associated neurotransmitter such as excitatory dopaminergic neurons and inhibitory GABAergic neurons. Cortical interneurons onlyGalanin-like peptide (591 words) [view diff] exact match in snippet view article find links to article
2009). "Galanin-like peptide stimulates feeding and sexual behavior via dopaminergic fibers within the medial preoptic area of adult male rats". Journal ofFoliglurax (290 words) [view diff] exact match in snippet view article find links to article
Gonzalez-Latapi P, Bhowmick SS, Saranza G, Fox SH (October 2020). "Non-Dopaminergic Treatments for Motor Control in Parkinson's Disease: An Update". CNSETM1 (90 words) [view diff] exact match in snippet view article find links to article
membrane membrane plasma membrane integral component of plasma membrane dopaminergic synapse glutamatergic synapse GABA-ergic synapse integral component ofFrizzled-1 (587 words) [view diff] exact match in snippet view article find links to article
DNA-templated signal transduction Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation beta-catenin destruction complex disassembly WntRAC1 (3,420 words) [view diff] exact match in snippet view article find links to article
cell population proliferation ruffle assembly lamellipodium assembly dopaminergic neuron differentiation cell-cell junction organization Fc-gamma receptorPOU domain (999 words) [view diff] exact match in snippet view article find links to article
protein to a sequence element regulating gene expression in specific dopaminergic neurons". Nature. 343 (6257): 467–470. doi:10.1038/343467a0. PMID 1967821O-Phenyl-3-iodotyramine (247 words) [view diff] exact match in snippet view article find links to article
"Trace amines depress D(2)-autoreceptor-mediated responses on midbrain dopaminergic cells". British Journal of Pharmacology. 160 (6): 1509–20. doi:10.1111/jFrizzled-3 (802 words) [view diff] exact match in snippet view article find links to article
integral component of membrane Biological process hair follicle development dopaminergic neuron axon guidance positive regulation of neuroblast proliferationFipexide (323 words) [view diff] exact match in snippet view article find links to article
Trabucchi M (February 1983). "[Fipexide: a new drug for the regulation of dopaminergic system at the macromolecular level]". Bollettino Chimico FarmaceuticoMonoamine neurotransmitter (1,409 words) [view diff] exact match in snippet view article find links to article
receptor 1 in the functional regulation of monoamine transporters and dopaminergic activity". J. Neurochem. 116 (2): 164–176. doi:10.1111/j.1471-4159.2010FOXA1 (802 words) [view diff] exact match in snippet view article find links to article
process Notch signaling pathway prostate gland stromal morphogenesis dopaminergic neuron differentiation positive regulation of intracellular estrogenCorticotropin-releasing hormone (2,919 words) [view diff] exact match in snippet view article find links to article
protein within the ventral tegmental area is expressed in a subset of dopaminergic neurons". The Journal of Comparative Neurology. 509 (3): 302–318. doi:10Alcohol myopia (2,665 words) [view diff] exact match in snippet view article find links to article
to analyze the probable outcomes of their actions. Alcohol activates dopaminergic circuits in the midbrain that also regulate the brain's analyzation andAntiporter (7,894 words) [view diff] exact match in snippet view article find links to article
neuronal cell death that characterize Parkinson's. In this case, if dopaminergic neurons of the substantia nigra are affected, it can contribute to thePentedrone (678 words) [view diff] exact match in snippet view article find links to article
designer compound pentedrone exhibits rewarding properties and affects dopaminergic activity". Addiction Biology. 22 (1): 117–128. doi:10.1111/adb.12299GBR-12783 (65 words) [view diff] exact match in snippet view article find links to article
A. T.; Lightfoot, J. T. (2012). "Pharmacological manipulation of the dopaminergic system affects wheel-running activity in differentially active mice"Prostaglandin D2 receptor (869 words) [view diff] exact match in snippet view article find links to article
progressive disease-like symptoms. They also discovered PGD2 receptors on dopaminergic cells but not on microglia. Eicosanoid receptor Prostaglandin E2 receptorPINK1 (2,677 words) [view diff] exact match in snippet view article find links to article
degradation. Parkinson's disease is often characterized by the degeneration of dopaminergic neurons and associated with the build-up of improperly folded proteinsCorticotropin-releasing hormone (2,919 words) [view diff] exact match in snippet view article find links to article
protein within the ventral tegmental area is expressed in a subset of dopaminergic neurons". The Journal of Comparative Neurology. 509 (3): 302–318. doi:10Cause of obsessive–compulsive disorder (3,408 words) [view diff] exact match in snippet view article find links to article
an underlying neurochemical etiology. Dopaminergic systems are implicated in OCD by the efficacy of dopaminergic agents, the fact that PANDAS may be implicatedAlcohol myopia (2,665 words) [view diff] exact match in snippet view article find links to article
to analyze the probable outcomes of their actions. Alcohol activates dopaminergic circuits in the midbrain that also regulate the brain's analyzation andGPR37 (1,103 words) [view diff] exact match in snippet view article find links to article
Nishimura I, Imai Y, Takahashi R, Lu B (March 2003). "Parkin suppresses dopaminergic neuron-selective neurotoxicity induced by Pael-R in Drosophila". NeuronCHRNB3 (745 words) [view diff] exact match in snippet view article find links to article
plasma membrane synapse cell junction acetylcholine-gated channel complex dopaminergic synapse integral component of plasma membrane neuron projection BiologicalBiogenic amine (1,436 words) [view diff] exact match in snippet view article find links to article
receptor 1 in the functional regulation of monoamine transporters and dopaminergic activity". J. Neurochem. 116 (2): 164–176. doi:10.1111/j.1471-4159.2010CDON (1,111 words) [view diff] exact match in snippet view article find links to article
development. CDON was shown to play a role in differentiation of midbrain dopaminergic neurons through the interference with of Shh signaling pathway. MutationsARMET (554 words) [view diff] exact match in snippet view article find links to article
mesencephalic, astrocyte-derived neurotrophic factor with selectivity for dopaminergic neurons". J Mol Neurosci. 20 (2): 173–88. doi:10.1385/JMN:20:2:173. PMID 12794311Azadirachtin (1,253 words) [view diff] exact match in snippet view article find links to article
digestive enzymes and could leave an aversive taste memory by activating dopaminergic neurons. Azadirachtin additionally has a long list of cellular and molecularCaffeine/ergotamine (376 words) [view diff] exact match in snippet view article find links to article
just as triptans do." This along with binding to other serotonergic and dopaminergic receptors is their presumed mechanism of action in treating migraineAmineptine (2,471 words) [view diff] exact match in snippet view article find links to article
PMID 3708219. Nishino S, Mao J, Sampathkumaran R, Shelton J (1998). "Increased dopaminergic transmission mediates the wake-promoting effects of CNS stimulants".LMX1B (1,074 words) [view diff] exact match in snippet view article find links to article
component nucleus Biological process multicellular organism development dopaminergic neuron differentiation in utero embryonic development regulation of transcriptionVentral pallidum (449 words) [view diff] exact match in snippet view article find links to article
of the thalamus. It is unclear whether the ventral pallidum receives dopaminergic inputs from the ventral tegmental area. The ventral pallidum receivesAaTX1 (434 words) [view diff] exact match in snippet view article find links to article
concentration of 250 nM, AaTX1 decreases the IA current amplitude by 90% in the dopaminergic neurons of the substantia nigra. IA currents, mediated by these specificTreatment-resistant depression (2,862 words) [view diff] exact match in snippet view article find links to article
dopaminergic stimulant such as methylphenidate, or even dextroamphetamine or methamphetamine can be helpful.[citation needed] Primarily dopaminergic orBazinaprine (187 words) [view diff] exact match in snippet view article find links to article
1987). "SR 95191, a selective inhibitor of type A monoamine oxidase with dopaminergic properties. II. Biochemical characterization of monoamine oxidase inhibition"Ream Al-Hasani (2,386 words) [view diff] no match in snippet view article find links to article
Ream Al-Hasani is a British neuroscientist and pharmacologist as well as an assistant professor of anesthesiology at Washington University in St. LouisQuinolinic acid (3,477 words) [view diff] exact match in snippet view article find links to article
Studies show that quinolinic acid is involved in the degeneration of the dopaminergic neurons in the substantia nigra (SN) of Parkinson's disease patientsSTX1A (2,987 words) [view diff] exact match in snippet view article find links to article
|alt=Nicotine Activity on Dopaminergic Neurons edit]] The interactive pathway map can be edited at WikiPathways: "NicotineDopaminergic_WP1602". STX1A has beenXanomeline (1,170 words) [view diff] exact match in snippet view article find links to article
pharmacology at the M2, M3 and M5 receptors. Xanomeline regulates key dopaminergic and glutamatergic circuits in the brain that are thought to be imbalancedWhite matter (2,188 words) [view diff] exact match in snippet view article find links to article
in the brain that appears darker due to higher levels of melanin in dopaminergic neurons than its nearby areas. Note that white matter can sometimes appearDimitri Krainc (1,333 words) [view diff] exact match in snippet view article find links to article
linked parkin mutation disrupts recycling of synaptic vesicles in human dopaminergic neurons. Neuron, 2023 Burbulla, L., Jeon, S., Zheng, J, Song, P, SilvermanBrasofensine (527 words) [view diff] exact match in snippet view article find links to article
symptoms do not begin to manifest until there has been an 80% reduction in dopaminergic neurons, particularly in the substantia nigra brain region. BrasofensineSigns and symptoms of Parkinson's disease (3,420 words) [view diff] exact match in snippet view article find links to article
by aromatic L-amino acid decarboxylase (AADC), which is found in both dopaminergic and serotonergic neurons, it is possible for serotonergic neurons toTyrosine hydroxylase (4,401 words) [view diff] exact match in snippet view article find links to article
A consistent abnormality in Parkinson's disease is degeneration of dopaminergic neurons in the substantia nigra, leading to a reduction of striatal dopamineLRRK2 (1,929 words) [view diff] exact match in snippet view article find links to article
Komatsu M, Holstein GR, Yue Z (May 2012). "Disrupted autophagy leads to dopaminergic axon and dendrite degeneration and promotes presynaptic accumulationSigma receptor (1,570 words) [view diff] exact match in snippet view article find links to article
(April 2004). "Involvement of the sigma 1 receptor in the modulation of dopaminergic transmission by amantadine". The European Journal of Neuroscience. 19EN1 (gene) (1,168 words) [view diff] exact match in snippet view article
negative regulation of neuron apoptotic process skeletal system development dopaminergic neuron differentiation proximal/distal pattern formation regulation ofTroll (EP) (150 words) [view diff] exact match in snippet view article
No. Title Length 1. "hedonic prison" 4:24 2. "bio-sewer" 4:00 3. "cyber bile" 6:48 4. "dopaminergic precision" 4:41 5. "sedentary seed" 5:20Troll (EP) (150 words) [view diff] exact match in snippet view article
No. Title Length 1. "hedonic prison" 4:24 2. "bio-sewer" 4:00 3. "cyber bile" 6:48 4. "dopaminergic precision" 4:41 5. "sedentary seed" 5:20J-113,397 (874 words) [view diff] exact match in snippet view article find links to article
signaling in rat substantia nigra pars reticulata stimulates nigrostriatal dopaminergic transmission and motor behavior". The Journal of Neuroscience. 24 (30):Mir-133 microRNA precursor family (1,472 words) [view diff] exact match in snippet view article find links to article
microRNA, mir133b, suppresses melanopsin expression mediated by failure dopaminergic amacrine cells in RCS rats". Cellular Signalling. 24 (3): 685–98. doi:10Decidua (804 words) [view diff] exact match in snippet view article find links to article
CRF, GnRH, prolactin, and relaxin. Decidual prolactin is not under dopaminergic control. Insulin-like growth factor-binding protein 1 (IGFBP1) also calledPlacebo (6,813 words) [view diff] exact match in snippet view article find links to article
frontal cortical areas that generate and maintain cognitive expectancies. Dopaminergic reward pathways may underlie these expectancies". "Diseases lacking majorAttention deficit hyperactivity disorder (27,036 words) [view diff] exact match in snippet view article find links to article
pathophysiology of ADHD, as well as imbalances in the noradrenergic and dopaminergic systems that mediate these brain regions. Genetic factors play an importantSB-216641 (312 words) [view diff] exact match in snippet view article find links to article
receptors within the ventral tegmental area in regulation of mesolimbic dopaminergic neuronal activity via GABA mechanisms: a study with dual-probe microdialysis"Astrocyte (9,291 words) [view diff] exact match in snippet view article find links to article
release of a hormone called prolactin from the pituitary. The activity of dopaminergic neurons declines during aging, leading to elevations in blood levelsAldehyde dehydrogenase (2,080 words) [view diff] exact match in snippet view article find links to article
model for PD etiology may help explain the selective vulnerability of dopaminergic neurons in PD and provide a potential mechanism through which environmentalFLOT1 (1,178 words) [view diff] exact match in snippet view article find links to article
junction external side of plasma membrane synapse presynaptic active zone dopaminergic synapse presynapse glutamatergic synapse GABA-ergic synapse BiologicalInternal globus pallidus (942 words) [view diff] exact match in snippet view article find links to article
and indirect striatopallidal pathways: Glutamatergic pathways are red, dopaminergic are magenta and GABAergic pathways are blue. STN: Subthalamic NucleusJudith R. Walters (268 words) [view diff] exact match in snippet view article find links to article
and her Ph.D. from Yale University. Her 1972 dissertation was titled Dopaminergic Neurons: Effect of Gamma-Hydroxybutyrate. She studied the pharmacologyPHOX2A (1,023 words) [view diff] exact match in snippet view article find links to article
nervous system development regulation of respiratory gaseous exchange dopaminergic neuron differentiation noradrenergic neuron differentiation locus ceruleusLeptin (13,116 words) [view diff] exact match in snippet view article find links to article
ventromedial nuclei, as well as other parts of the hypothalamus and dopaminergic neurons of the ventral tegmental area, consequently mediating feedingLorenz Studer (1,422 words) [view diff] exact match in snippet view article find links to article
successfully demonstrated that upon transplantation, these newly developed dopaminergic neurons can improve clinical symptoms in Parkinsonian rat models. OverStereotypy (1,361 words) [view diff] exact match in snippet view article find links to article
Punding may occur in individuals with Parkinson's disease treated with dopaminergic agents such as L-DOPA. Tweaking is a slang term for compulsive or repetitiveMethylergometrine (1,144 words) [view diff] exact match in snippet view article find links to article
"Ergot Alkaloids and their Derivatives as Ligands for Serotoninergic, Dopaminergic, and Adrenergic Receptors". In Křen V, Cvak L (eds.). Ergot: the genusAlpha-1B adrenergic receptor (1,333 words) [view diff] exact match in snippet view article find links to article
receptor has been shown to interact with AP2M1. A role in regulation of dopaminergic neurotransmission has also been suggested. Adrenergic receptor GRCh38:Indantadol (470 words) [view diff] exact match in snippet view article find links to article
(September 2001). "Anticonvulsant preclinical profile of CHF 3381: dopaminergic and glutamatergic mechanisms". Pharmacology Biochemistry and BehaviorGIMIAS (1,086 words) [view diff] exact match in snippet view article find links to article
quantification of the striatal uptake in neurotransmission SPECT studies of the dopaminergic system. I. Larrabide, P. Omedas, Y. Martelli, X. Planes, M. Nieber, JPomaglumetad (3,035 words) [view diff] exact match in snippet view article find links to article
effective in treating psychosis without any apparent interference in dopaminergic function. Existing antipsychotic medications primarily treat schizophreniaNeural stem cell (4,181 words) [view diff] exact match in snippet view article find links to article
of this technique is the targeted differentiation of ventral midbrain dopaminergic (DAergenic) neurons into different models of PD. Current therapies forDKK1 (1,959 words) [view diff] exact match in snippet view article find links to article
signal transduction regulation of dopaminergic neuron differentiation positive regulation of midbrain dopaminergic neuron differentiation negative regulationPhosphodiesterase inhibitor (2,348 words) [view diff] exact match in snippet view article find links to article
"Paraxanthine, the primary metabolite of caffeine, provides protection against dopaminergic cell death via stimulation of ryanodine receptor channels". MolecularFusiform gyrus (1,966 words) [view diff] exact match in snippet view article find links to article
recognition task. Dopamine is known to be related to the reward system. The dopaminergic system shows an active response to stimuli that predict possible rewardsHypomania (2,021 words) [view diff] exact match in snippet view article find links to article
pathophysiology is usually assumed to be the same. Given that norepinephrine and dopaminergic drugs are capable of triggering hypomania, theories relating to monoamineFOXA2 (1,550 words) [view diff] exact match in snippet view article find links to article
component cytoplasm nucleoplasm cell junction nucleus Biological process dopaminergic neuron differentiation regulation of insulin secretion involved in cellularIsoquinoline (1,037 words) [view diff] exact match in snippet view article find links to article
to Parkinson's disease in the 1980s. The active neurotoxins destroy dopaminergic neurons, leading to parkinsonism and Parkinson's disease. SeveralIoflupane (123I) (758 words) [view diff] exact match in snippet view article
the brain. A feature of Parkinson's disease is a marked reduction in dopaminergic neurons in the striatal region. By introducing an agent that binds toSB-242084 (564 words) [view diff] exact match in snippet view article find links to article
"SB 242084, a selective serotonin2C receptor antagonist, increases dopaminergic transmission in the mesolimbic system". Neuropharmacology. 38 (8): 1195–205Alpha-1 adrenergic receptor (1,528 words) [view diff] exact match in snippet view article find links to article
PMID 14634460. Cheng JT, Kuo DY (August 2003). "Both alpha1-adrenergic and D(1)-dopaminergic neurotransmissions are involved in phenylpropanolamine-mediated feedingIoflupane (123I) (758 words) [view diff] exact match in snippet view article
the brain. A feature of Parkinson's disease is a marked reduction in dopaminergic neurons in the striatal region. By introducing an agent that binds toNeuron (8,964 words) [view diff] exact match in snippet view article find links to article
synthesized from the amino acid glutamine by the enzyme glutamate synthase. Dopaminergic neurons—dopamine. Dopamine is a neurotransmitter that acts on D1 typeSNAP25 (5,006 words) [view diff] exact match in snippet view article find links to article
|alt=Nicotine Activity on Dopaminergic Neurons edit]] The interactive pathway map can be edited at WikiPathways: "NicotineDopaminergic_WP1602". SNAP-25 hasSKF-83,959 (465 words) [view diff] exact match in snippet view article find links to article
Holden, K. G., Hahn, R. A., Wardell, J. R., Alfonso, J. T. (April 1982). "Dopaminergic activity of substituted 6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines"Isoquinoline (1,037 words) [view diff] exact match in snippet view article find links to article
to Parkinson's disease in the 1980s. The active neurotoxins destroy dopaminergic neurons, leading to parkinsonism and Parkinson's disease. SeveralPHOX2B (1,363 words) [view diff] exact match in snippet view article find links to article
development in a lateral line nerve neuron differentiation neuron migration dopaminergic neuron differentiation noradrenergic neuron differentiation positiveGrowth differentiation factor (1,271 words) [view diff] exact match in snippet view article find links to article
factor 5 on the survival and morphology of embryonic rat midbrain dopaminergic neurones in vitro". J Neurocytol. 33 (5): 479–88. doi:10.1007/s11068-004-0511-yDynamin-like 120 kDa protein (1,957 words) [view diff] exact match in snippet view article find links to article
D (2016). "Quantification of mitochondrial morphology in neurites of dopaminergic neurons using multiple parameters". J Neurosci Methods. 262: 56–65. doi:10Adenosine receptor (1,954 words) [view diff] exact match in snippet view article find links to article
PSB 36 A2A ADORA2A Gs → cAMP↑ Coronary artery vasodilatation Decreased dopaminergic activity in CNS Inhibition of central neuron excitation. N6-3-methoxyl-4-hydroxybenzylAmacrine cell (1,448 words) [view diff] exact match in snippet view article find links to article
understood. Another subtype of GABAergic amacrine cells are those that are dopaminergic. These are all TH expressing and these amacrine cells modulate lightNeuroepigenetics (3,869 words) [view diff] exact match in snippet view article find links to article
nervous system. Studies have shown that accumulation of manganese leads to dopaminergic cell death and consequently plays a role in the onset of Parkinson'sTiapride (1,692 words) [view diff] exact match in snippet view article find links to article
treating these affective disorders. Moreover, its selectivity for the dopaminergic system is thought to account for its avoidance of the side effects typicallyPathophysiology (2,712 words) [view diff] exact match in snippet view article find links to article
patron saint. The pathophysiology of Parkinson's disease is death of dopaminergic neurons as a result of changes in biological activity in the brain withMetitepine (492 words) [view diff] exact match in snippet view article find links to article
of rats previously treated with methiothepin: possible involvement of dopaminergic system". Pharmacol. Biochem. Behav. 23 (1): 43–8. doi:10.1016/0091-3057(85)90128-5Bita Moghaddam (2,386 words) [view diff] exact match in snippet view article find links to article
in the Department of Psychiatry exploring the modulatory effects of dopaminergic signalling in the striatum. Moghaddam published 6 first author papersAdenosine A2A receptor antagonist (2,064 words) [view diff] exact match in snippet view article find links to article
neuroprotectors for their ability to reduce neuroinflammation. The degradation of dopaminergic neurons in the nigrostriatal pathway is the cause of the motor symptomsMDAI (1,576 words) [view diff] exact match in snippet view article find links to article
1991). "Serotonin neurotoxicity in rats after combined treatment with a dopaminergic agent followed by a nonneurotoxic 3,4-methylenedioxymethamphetamine (MDMA)Actoprotector (760 words) [view diff] exact match in snippet view article find links to article
upregulation of tyrosine hydroxylase, thereby indirectly increasing dopaminergic signaling in the brain. The action of amphetamine (a phenethylamine psychostimulant)Vesicular monoamine transporter (4,993 words) [view diff] exact match in snippet view article find links to article
on the understanding the increased cytosolic dopamine levels lead to dopaminergic cell death in PD, it has been proposed that regulatory polymorphismsGrowth hormone secretagogue receptor (1,600 words) [view diff] exact match in snippet view article find links to article
do indeed form dimers, this would somehow link ghrelin signaling to dopaminergic signaling. The growth hormone secretagogue receptor may also be linkedPukateine (270 words) [view diff] exact match in snippet view article find links to article
Silveira R, Protais P, Russell G, Cassels BK, Dajas F (March 1999). "Dopaminergic pharmacology and antioxidant properties of pukateine, a natural productAdenosine A2A receptor (5,102 words) [view diff] exact match in snippet view article find links to article
S2CID 44883687. Jenner P (December 2003). "A2A antagonists as novel non-dopaminergic therapy for motor dysfunction in PD". Neurology. 61 (11 Suppl 6): S32-8Atypical antipsychotic (9,280 words) [view diff] exact match in snippet view article find links to article
in order to effectively treat schizophrenia. D2 Receptor: Hyperactive dopaminergic activity on D2 receptors in the mesolimbic pathway is responsible forS-15535 (368 words) [view diff] exact match in snippet view article find links to article
Millan MJ (1998). "Induction of burst firing in ventral tegmental area dopaminergic neurons by activation of serotonin (5-HT)1A receptors: WAY 100,635-reversibleMefway (18F) (937 words) [view diff] exact match in snippet view article
Ryu YH, Cho WG, Jeon TJ, Lyoo CH, Kang YW, et al. (December 2014). "Dopaminergic neuron destruction reduces hippocampal serotonin 1A receptor uptake ofSB-206553 (786 words) [view diff] exact match in snippet view article find links to article
blockade of serotonin-2C/2B receptors enhances mesolimbic and mesostriatal dopaminergic function: a combined in vivo electrophysiological and microdialysis study"Heteroreceptor (498 words) [view diff] exact match in snippet view article find links to article
"Reciprocal autoreceptor and heteroreceptor control of serotonergic, dopaminergic and noradrenergic transmission in the frontal cortex: Relevance to theArmodafinil (1,872 words) [view diff] exact match in snippet view article find links to article
2014-10-14. Qu WM, Huang ZL, Xu XH, Matsumoto N, Urade Y (August 2008). "Dopaminergic D1 and D2 receptors are essential for the arousal effect of modafinil"Vitamin D and neurology (2,597 words) [view diff] exact match in snippet view article find links to article
of movement and coordination. Patients with Parkinson's disease lose dopaminergic (DA) neurons in the substantia nigra, a part of the brain that playsToxicity (3,097 words) [view diff] exact match in snippet view article find links to article
effects include anticholinergic effects, alpha-adrenergic blockade, and dopaminergic effects, among others. Toxicity can be measured by its effects on theA-77636 (737 words) [view diff] exact match in snippet view article find links to article
JR, Jackson LL, Meador-Woodruff JH, Jing D, Deutch AY (June 2005). "Dopaminergic regulation of orexin neurons" (PDF). The European Journal of NeuroscienceArtificial brain (1,309 words) [view diff] exact match in snippet view article find links to article
5 million neurons, includes features of the visual and motor cortices, GABAergic and dopaminergic connections, the ventral tegmental area (VTA), substantia nigra, andGabapentin enacarbil (648 words) [view diff] exact match in snippet view article find links to article
"Gabapentin enacarbil (XP13512/GSK1838262) as an alternative treatment to dopaminergic agents for restless legs syndrome". Expert Opinion on PharmacotherapyGRK6 (1,750 words) [view diff] exact match in snippet view article find links to article
Macrae AD, Torres GE, Kim KM, Lefkowitz RJ, Caron MG, Premont RT (2003). "Dopaminergic supersensitivity in G protein-coupled receptor kinase 6-deficient mice"Gray's biopsychological theory of personality (2,889 words) [view diff] exact match in snippet view article find links to article
psycho-pathological or dis-inhibitory disorders. Certain aspects of the dopaminergic reward system activate when reward cues and reinforcers are presented