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searching for Neural stem cell 82 found (130 total)

Stroke in China (996 words) [view diff] exact match in snippet view article find links to article

brain ischemia/reperfusion exploring, leukoencephalopathy (CADASIL), neural stem cell and stroke, neuroprotective treatment for stroke, clinical therapy

Neuroimmunology (2,796 words) [view diff] no match in snippet view article find links to article

Neuroimmunology is a field combining neuroscience, the study of the nervous system, and immunology, the study of the immune system. Neuroimmunologists

MiR-137 (2,115 words) [view diff] exact match in snippet view article find links to article

schizophrenia and other psychiatric disorders. miR-137 is shown to regulate neural stem cell proliferation and differentiation in mouse embryonic stem cells, and

Arnold Kriegstein (826 words) [view diff] exact match in snippet view article find links to article

Cell Research from 2004 to 2021. His main research interests include neural stem cell and brain development. He is a member of the National Academy of Medicine

Fanconi anemia (4,139 words) [view diff] exact match in snippet view article find links to article

and later during adult neurogenesis. This leads to depletion of the neural stem cell pool with aging. Much of the Fanconi anemia phenotype might be interpreted

Serrate RNA effector molecule homolog (569 words) [view diff] exact match in snippet view article find links to article

its activity on miRNAs, it is necessary and sufficient to promote neural stem cell self-renewal, by directly binding to the SOX2 promoter and positively

Injury-induced stem-cell niche (433 words) [view diff] exact match in snippet view article find links to article

injured CNS through the establishment of atypical ectopic perivascular neural stem cell niches". Archives Italiennes de Biologie. 148 (2): 173–183. PMID 20830978

TLX (936 words) [view diff] exact match in snippet view article find links to article

maintaining their undifferentiated state. Furthermore, TLX regulates adult neural stem cell proliferation. Removal of TLX from the adult mouse brain resulted in

Reflectin (1,621 words) [view diff] exact match in snippet view article find links to article

human neural and progenitor cells. Using reflectin as a material for neural stem cell growth Reflectins have been heterologously expressed in mammalian cells

Polycomb-group proteins (1,435 words) [view diff] exact match in snippet view article find links to article

cell self-renewal. The Bmi1 polycomb ring finger protein promotes neural stem cell self-renewal. Murine null mutants in PRC2 genes are embryonic lethals

CPNE1 (1,863 words) [view diff] exact match in snippet view article find links to article

importance in the neural stem cell functions in the course of brain development. Where it is detrimental in regulating the neural stem cell functions throughout

Stem-cell niche (8,026 words) [view diff] exact match in snippet view article find links to article

their niche are under intense research and debate.[citation needed] Neural stem cell niches are divided in two : the Subependymal zone (SEZ) and the Subgranular

Mir-184 (2,166 words) [view diff] exact match in snippet view article find links to article

deficiency. Numblike (Numbl) is known to be important in embryonic neural stem cell function and cortical brain development and has been identified as

Ependyma (641 words) [view diff] exact match in snippet view article find links to article

Clarke DL, Risling M, Lendahl U, Frisen J (1999). "Identification of a neural stem cell in the adult mammalian central nervous system". Cell. 96 (1): 25–34

Ann Tsukamoto (1,431 words) [view diff] exact match in snippet view article find links to article

second candidate stem cell for the liver. Under her guidance, the human neural stem cell transitioned into early clinical development for all three components

T-0156 (87 words) [view diff] case mismatch in snippet view article find links to article

Carreira, BP; Nobre, RJ; Carvalho, CM; Araújo, IM (2014). "Stimulation of Neural Stem Cell Proliferation by Inhibition of Phosphodiesterase 5". Stem Cells International

Mir-26 microRNA precursor family (3,054 words) [view diff] exact match in snippet view article find links to article

differentiation The expression of genes which, upon activation, induce neural stem cell differentiation into neurons are suppressed by a group of phosphatases

Cholera toxin (3,334 words) [view diff] exact match in snippet view article find links to article

which enables visualisation of neuronal pathways. Additionally, in neural stem cell research, CTB has been observed to influence the localisation of the

François Guillemot (598 words) [view diff] case mismatch in snippet view article find links to article

Academy of Medical Sciences. Retrieved 20 August 2022. "Guillemot Lab: Neural Stem Cell Biology Laboratory". Francis Crick Institute. Retrieved 18 August 2022

Max Planck Institute for Molecular Genetics (225 words) [view diff] case mismatch in snippet view article find links to article

Cell Chromatin Group (Aydan Bulut-Karslioglu) Lab for Human Brain & Neural Stem Cell Studies (Yechiel Elkabetz) Precision Gene Control group (Denes Hnisz)

Basement membrane (1,239 words) [view diff] exact match in snippet view article find links to article

zone fractones are speckled basement membranes that function as a neural stem cell niche". Molecular Biology of the Cell. 30 (1): 56–68. doi:10.1091/mbc

FANCG (2,456 words) [view diff] exact match in snippet view article find links to article

2008). This effect persists in adulthood leading to depletion of the neural stem cell pool with aging. The FA phenotype can be interpreted as a premature

NTERA-2 (570 words) [view diff] exact match in snippet view article find links to article

"The human NTERA2 neural cell line generates neurons on growth under neural stem cell conditions and exhibits characteristics of radial glial cells". Mol

BMI1 (2,644 words) [view diff] exact match in snippet view article find links to article

He S, Bydon M, Morrison SJ, Pardal R (June 2005). "Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival

CHL1 (839 words) [view diff] exact match in snippet view article find links to article

Lim SD, Stallcup W, Lefkove B, et al. (2007). "Expression of the neural stem cell markers NG2 and L1 in human angiomyolipoma: are angiomyolipomas neoplasms

Samuel Weiss (neurobiologist) (699 words) [view diff] exact match in snippet view article

committees, has authored many publications, holds key patents in the neural stem cell field and has founded two biotechnology companies. The second company

Sean J. Morrison (2,332 words) [view diff] exact match in snippet view article find links to article

Morrison, Sean J. (October 2003). "Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation". Nature. 425 (6961): 962–967

Mir-351 microRNA precursor family (219 words) [view diff] exact match in snippet view article find links to article

2012). "MicroRNA-351 regulates TMEM 59 (DCF1) expression and mediates neural stem cell morphogenesis". RNA Biology. 9 (3): 292–301. doi:10.4161/rna.19100

HES5 (754 words) [view diff] exact match in snippet view article find links to article

and histogenesis of the nervous system by control of the timing of neural stem cell differentiation". Development. 131 (22): 5539–5550. doi:10.1242/dev

Allodynia (1,874 words) [view diff] exact match in snippet view article find links to article

Lilja JA (March 2005). "Allodynia limits the usefulness of intraspinal neural stem cell grafts; directed differentiation improves outcome". Nature Neuroscience

Mir-9/mir-79 microRNA precursor family (1,744 words) [view diff] exact match in snippet view article find links to article

feedback regulatory loop involving microRNA-9 and nuclear receptor TLX in neural stem cell fate determination". Nat Struct Mol Biol. 16 (4): 365–71. doi:10.1038/nsmb

Dipropylcyclopentylxanthine (633 words) [view diff] exact match in snippet view article find links to article

Sakurada K (October 2008). "Activation of adenosine A1 receptor-induced neural stem cell proliferation via MEK/ERK and Akt signaling pathways". Journal of Neuroscience

Rostral migratory stream (3,228 words) [view diff] exact match in snippet view article find links to article

PMC 3866012. PMID 20670825. Conover, Joanne; Notti, Ryan (2007). "The neural stem cell niche". Cell and Tissue Research. 331 (1): 211–224. doi:10.1007/s00441-007-0503-6

Elena Cattaneo (1,068 words) [view diff] exact match in snippet view article find links to article

specialized at the Massachusetts Institute of Technology. She studied neural stem cell differentiation in the area of the human brain associated with degenerative

Fractone (974 words) [view diff] exact match in snippet view article find links to article

zone fractones are speckled basement membranes that function as a neural stem cell niche". Molecular Biology of the Cell. 30 (1): 56–68. doi:10.1091/mbc

Neuralstem, Inc. (416 words) [view diff] exact match in snippet view article find links to article

injury. Neuralstem also maintains the ability to generate stable human neural stem cell lines suitable for systematic screening of large chemical libraries

CHD7 (1,578 words) [view diff] exact match in snippet view article find links to article

Hegg CC, Raphael Y, Martens JR, Martin DM (Jun 2009). "Defects in neural stem cell proliferation and olfaction in Chd7 deficient mice indicate a mechanism

Yihua An (279 words) [view diff] exact match in snippet view article find links to article

Chongran, et al. "Modulation of the major histocompatibility complex by neural stem cell-derived neurotrophic factors used for regenerative therapy in a rat

Jay Pasricha (987 words) [view diff] exact match in snippet view article find links to article

POEM in humans. On the bench research side, he pioneered the use of neural stem cell transplantation for disorders of gastrointestinal motility. Notably

FANCA (4,761 words) [view diff] exact match in snippet view article find links to article

repair. This effect persists in adulthood leading to depletion of the neural stem cell pool with aging. The Fanconi anemia phenotype can be interpreted as

Zebrafish (12,494 words) [view diff] case mismatch in snippet view article find links to article

PMID 24706895. Kizil C (January 2018). "Mechanisms of Pathology-Induced Neural Stem Cell Plasticity and Neural Regeneration in Adult Zebrafish Brain". Current

Interleukin 4 (2,297 words) [view diff] case mismatch in snippet view article find links to article

Mashkaryan V, Froc C, et al. (October 2016). "IL4/STAT6 Signaling Activates Neural Stem Cell Proliferation and Neurogenesis upon Amyloid-β42 Aggregation in Adult

Ronald DePinho (1,217 words) [view diff] case mismatch in snippet view article find links to article

(November 2009). "FoxOs Cooperatively Regulate Diverse Pathways Governing Neural Stem Cell Homeostasis". Cell Stem Cell. 5 (5): 540–553. doi:10.1016/j.stem.2009

NLRP2 (1,501 words) [view diff] exact match in snippet view article find links to article

patients and healthy controls in the transition between iPS cell and neural stem cell stages". Translational Psychiatry. 7 (1): e1010. doi:10.1038/tp.2016

ID4 (3,045 words) [view diff] exact match in snippet view article find links to article

early cortical progenitors. It is complexly involved in regulating neural stem cell proliferation and differentiation by inhibiting proliferation of differentiating

CRABP1 (1,447 words) [view diff] exact match in snippet view article find links to article

and neural stem cells. Knockout mice without CRABP1 showed increased neural stem cell proliferation and thus hippocampus neurogenesis. Furthermore, learning

Translational glycobiology (1,592 words) [view diff] exact match in snippet view article find links to article

brain barrier. Additionally, glycoengineering has been utilized with neural stem cell cultures to increase adhesion to the extracellular matrix through the

Floor plate (biology) (1,961 words) [view diff] exact match in snippet view article

also reside in the FP region of the spinal cord. These cells are a neural stem cell population responsible for repopulating lost cells during injury. These

Bromodeoxyuridine (1,088 words) [view diff] exact match in snippet view article find links to article

Weidner, Norbert; Aigner, Ludwig (2011). "The dark side of BrdU in neural stem cell biology: Detrimental effects on cell cycle, differentiation and survival"

Glia (3,808 words) [view diff] exact match in snippet view article find links to article

Risling M, Lendahl U, Frisén J (January 1999). "Identification of a neural stem cell in the adult mammalian central nervous system". Cell. 96 (1): 25–34

HES1 (2,892 words) [view diff] exact match in snippet view article find links to article

and histogenesis of the nervous system by control of the timing of neural stem cell differentiation". Development. 131 (22): 5539–5550. doi:10.1242/dev

OLIG2 (3,206 words) [view diff] exact match in snippet view article find links to article

for OLIG2 in glioma progression. It is believed that OLIG2 promotes neural stem cell and progenitor cell proliferation by opposing p53 pathway, which potentially

Christopher Gregg (588 words) [view diff] exact match in snippet view article find links to article

before receiving his PhD from the University of Calgary in Canada in neural stem cell biology. While working with Samuel Weiss at the Hotchkiss Brain Institute

Wolfgang A. Tomé (937 words) [view diff] no match in snippet view article find links to article

"Preservation of memory with conformal avoidance of the hippocampal neural stem-cell compartment during whole-brain radiotherapy for brain metastases (RTOG

EGFL7 (2,109 words) [view diff] exact match in snippet view article find links to article

factor-like domain 7 (EGFL7) modulates Notch signalling and affects neural stem cell renewal". Nat. Cell Biol. 11 (7): 873–80. doi:10.1038/ncb1896. PMID 19503073

Notch signaling pathway (11,032 words) [view diff] exact match in snippet view article find links to article

Gaiano N, Fishell G (2002). "The role of notch in promoting glial and neural stem cell fates". Annual Review of Neuroscience. 25 (1): 471–490. doi:10.1146/annurev

Xenopus (5,807 words) [view diff] exact match in snippet view article find links to article

Gaiano N, Fishell G (2002). "The role of notch in promoting glial and neural stem cell fates". Annual Review of Neuroscience. 25 (1). Annual Reviews: 471–490

Motor neuron diseases (2,166 words) [view diff] exact match in snippet view article find links to article

localization in spinal motor neurons of TDP43. In TDP-43 depleted human neural stem cell-derived motor neurons, as well as in sporadic ALS patients' spinal

Behavioral epigenetics (7,936 words) [view diff] exact match in snippet view article find links to article

Juliandi B, Abematsu M, Nakashima K (Aug 2010). "Epigenetic regulation in neural stem cell differentiation". Development, Growth & Differentiation. 52 (6): 493–504

Wnt signaling pathway (7,432 words) [view diff] exact match in snippet view article find links to article

nervous system cells, which is further evidence of a role in promoting neural stem cell proliferation. Wnt signaling is involved in germ cell determination

Wnt signaling pathway (7,432 words) [view diff] exact match in snippet view article find links to article

nervous system cells, which is further evidence of a role in promoting neural stem cell proliferation. Wnt signaling is involved in germ cell determination

TAR DNA-binding protein 43 (4,646 words) [view diff] exact match in snippet view article find links to article

complex that then acts to seal the DNA breaks. In TDP-43 depleted human neural stem cell-derived motor neurons, as well as in sporadic ALS patients' spinal

Long-term impact of alcohol on the brain (5,291 words) [view diff] exact match in snippet view article find links to article

drinking) causes a decrease in hippocampal neurogenesis, via decreases in neural stem cell proliferation and newborn cell survival. Alcohol decreases the number

Niemann–Pick disease type C (5,033 words) [view diff] exact match in snippet view article find links to article

PMID 16940355. Ahmad I, Hunter RE, Flax JD, Snyder EY, Erickson RP (2007). "Neural stem cell implantation extends life in Niemann-Pick C1 mice". Journal of Applied

Gyrification (4,562 words) [view diff] exact match in snippet view article find links to article

timing of infection as well as its severity during the schedule of neural stem cell proliferation and neurogenesis. Earlier infections would generally

Fibrin scaffold (3,814 words) [view diff] exact match in snippet view article find links to article

Keung AJ, Irwin EF, et al. (November 2008). "Substrate modulus directs neural stem cell behavior". Biophysical Journal. 95 (9): 4426–38. Bibcode:2008BpJ..

Cell culture (8,466 words) [view diff] case mismatch in snippet view article find links to article

PMID 9548074. Pacey L, Stead S, Gleave J, Tomczyk K, Doering L (2006). "Neural Stem Cell Culture: Neurosphere generation, microscopical analysis and cryopreservation"

Life Length (2,065 words) [view diff] case mismatch in snippet view article find links to article

Brüstle, O. (2018). "A Stably Self-Renewing Adult Blood-derived Induced Neural Stem Cell Exhibiting Pattern Ability and Epigenetic Rejuvenation". Nature Communications

Let-7 microRNA family (8,447 words) [view diff] no match in snippet view article find links to article

loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment". Nature Cell Biology. 10 (8): 987–993. doi:10.1038/ncb1759

Genetically modified animal (10,789 words) [view diff] exact match in snippet view article find links to article

example, gene knockouts of the Sox2 gene confirm this region's role in neural stem cell amplification in the axolotl. The technology to do more complex conditional

Chlorpyrifos (11,542 words) [view diff] exact match in snippet view article find links to article

neurobehavioral teratogenicity in mice by nicotine administration and neural stem cell transplantation". Behavioural Brain Research. 205 (2): 499–504. doi:10

University of Georgia (23,811 words) [view diff] exact match in snippet view article find links to article

of the results of Center research is a new drug that is the first neural stem cell therapy that targets brain inflammation of ischemic stroke patients

Pediatric ependymoma (4,967 words) [view diff] exact match in snippet view article find links to article

Ependymomas have been suggested to arise from radial glial cells, suggesting neural stem cell maintenance pathways such as Notch, sonic hedgehog (SHH), and p53 are

Michael Sofroniew (2,110 words) [view diff] exact match in snippet view article find links to article

Harley I.; Sofroniew, Michael V. (April 1, 2003). "The predominant neural stem cell isolated from postnatal and adult forebrain but not early embryonic

Stem cell marker (5,691 words) [view diff] exact match in snippet view article find links to article

Walder S, Zhang F, Ferretti P (December 2003). "Up-regulation of neural stem cell markers suggests the occurrence of dedifferentiation in regenerating

Biochemical cascade (11,432 words) [view diff] exact match in snippet view article find links to article

Kim, I; Chada, K; Morrison, SJ (17 October 2008). "Hmga2 promotes neural stem cell self-renewal in young but not old mice by reducing p16Ink4a and p19Arf

Hedgehog pathway inhibitor (3,866 words) [view diff] exact match in snippet view article find links to article

24;109(17):E1038-47. Stecca B, i Altaba AR. A GLI1‐p53 inhibitory loop controls neural stem cell and tumour cell numbers. The EMBO Journal. 2009 Mar 18;28(6):663-76

Bio-MEMS (9,857 words) [view diff] exact match in snippet view article find links to article

H.; Lee, Abraham P.; Monuki, Edwin S.; Jeon, Noo Li (2005). "Human neural stem cell growth and differentiation in a gradient-generating microfluidic device"

Microfluidic cell culture (5,884 words) [view diff] case mismatch in snippet view article find links to article

Anna; Herland, Anna (July 2024). "On‐Chip Neural Induction Boosts Neural Stem Cell Commitment: Toward a Pipeline for iPSC‐Based Therapies". Advanced Science

Foetal brain cell graft (2,412 words) [view diff] exact match in snippet view article find links to article

Rechavi, Gideon (2009-02-17). "Donor-derived brain tumor following neural stem cell transplantation in an ataxia telangiectasia patient". PLOS Medicine

FOXG1 syndrome (3,519 words) [view diff] exact match in snippet view article find links to article

expression of p21, a low level of p21 contributes to the expansion of the neural stem cell pool and prevents early cell cycle exit. Alongside the expansion of

Murine respirovirus (32,094 words) [view diff] case mismatch in snippet view article find links to article

et al. (December 2009). "Brain Tumor Stem-Like Cells Identified by Neural Stem Cell Marker CD15". Translational Oncology. 2 (4): 247–257. doi:10.1593/tlo