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Longer titles found: Toll-like receptor 1 (view), Toll-like receptor 10 (view), Toll-like receptor 11 (view), Toll-like receptor 2 (view), Toll-like receptor 3 (view), Toll-like receptor 4 (view), Toll-like receptor 5 (view), Toll-like receptor 6 (view), Toll-like receptor 7 (view), Toll-like receptor 8 (view), Toll-like receptor 9 (view)

searching for Toll-like receptor 297 found (489 total)

alternate case: toll-like receptor

Poly ICLC (122 words) [view diff] no match in snippet view article find links to article

polylysine. It is under trial for use in cancer. Poly I:C is a ligand for toll like receptor-3, which usually triggers on the structurally similar double-stranded
IRAK2 (704 words) [view diff] exact match in snippet view article find links to article
O'Neill LA (Sep 2001). "Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction". Nature. 413 (6851): 78–83. Bibcode:2001Natur
TICAM2 (493 words) [view diff] exact match in snippet view article find links to article
Information, U.S. National Library of Medicine. "Entrez Gene: TICAM2 toll-like receptor adaptor molecule 2". Sullivan C, Postlethwait JH, Lage CR, et al.
Polyinosinic:polycytidylic acid (407 words) [view diff] exact match in snippet view article find links to article
to simulate viral infections. Poly I:C is known to interact with toll-like receptor 3 (TLR3), which is expressed at the endosomal membrane of B-cells
Resiquimod (569 words) [view diff] exact match in snippet view article find links to article
macrophages. It has several mechanisms of action, being both an agonist for toll-like receptor 7 and 8, and an upregulator of the opioid growth factor receptor.
Entolimod (1,044 words) [view diff] exact match in snippet view article find links to article
treatment. Entolimod is a recombinant protein that acts as an agonist of toll-like receptor 5 (TLR5), an innate immunity receptor. Entolimod activation of TLR5
CpG oligodeoxynucleotide (1,393 words) [view diff] case mismatch in snippet view article find links to article
CpG PAMP is recognized by the pattern recognition receptor (PRR) Toll-Like Receptor 9 (TLR9), which is constitutively expressed only in B cells and plasmacytoid
Pokeweed mitogen (634 words) [view diff] exact match in snippet view article find links to article
proliferation of B cells, plasma cells and T cells. This lectin contains Toll-like receptor 4 (TLR4) proteins which signals for the B-cell for a proliferative
LILRA4 (548 words) [view diff] exact match in snippet view article find links to article
"Plasmacytoid dendritic cell–specific receptor ILT7–FcɛRIγ inhibits Toll-like receptor–induced interferon production". J. Exp. Med. 203 (6): 1399–405. doi:10
Lipid A (1,377 words) [view diff] exact match in snippet view article find links to article
processes. Lipid A (and LPS) has been demonstrated to activate cells via Toll-like receptor 4 (TLR4), MD-2 and CD14 on the cell surface. Consequently, lipid A
PIK3AP1 (421 words) [view diff] exact match in snippet view article find links to article
signaling toll-like receptor 9 signaling pathway toll-like receptor 2 signaling pathway toll-like receptor 4 signaling pathway toll-like receptor 7 signaling
Akiko Iwasaki (1,745 words) [view diff] exact match in snippet view article find links to article
infections. According to Google Scholar, one of her publications, "Toll-like receptor control of the adaptive immune response," has been cited over 5,300
Ubiquitin A-52 residue ribosomal protein fusion product 1 (825 words) [view diff] exact match in snippet view article find links to article
pathway regulation of type I interferon production TRIF-dependent toll-like receptor signaling pathway Fc-epsilon receptor signaling pathway endosomal
RAB7B (411 words) [view diff] exact match in snippet view article find links to article
selectively expressed in monocytic cells. By promoting the degradation of toll-like receptor 4, RAB7B can negatively regulate the inflammatory activation of macrophages
IRF7 (1,417 words) [view diff] exact match in snippet view article find links to article
MyD88-independent toll-like receptor signaling pathway positive regulation of type I interferon production innate immune response regulation of MyD88-dependent toll-like
Protease-activated receptor 2 (2,703 words) [view diff] exact match in snippet view article find links to article
regulation of toll-like receptor 4 signaling pathway positive regulation of I-kappaB kinase/NF-kappaB signaling positive regulation of toll-like receptor 2 signaling
HspE7 (1,008 words) [view diff] exact match in snippet view article find links to article
already infected with HPV. The candidate is being developed with a Toll-like receptor 3 (TLR3) agonist adjuvant for multiple indications, including cervical
40S ribosomal protein S27a (929 words) [view diff] exact match in snippet view article find links to article
pathway regulation of type I interferon production TRIF-dependent toll-like receptor signaling pathway Fc-epsilon receptor signaling pathway endosomal
Black guineafowl (656 words) [view diff] exact match in snippet view article find links to article
currently known to researchers. The black guineafowl's genome includes a toll-like receptor (TLR1) which plays an important role in the bird's immune system.
(+)-Morphine (302 words) [view diff] exact match in snippet view article
derives its antianalgesic effects by being a selective-agonist of the Toll-like receptor 4 (TLR4), which due to not binding to opioid receptors allows it to
PELI1 (510 words) [view diff] exact match in snippet view article find links to article
SH (Sep 2006). "Smad6 negatively regulates interleukin 1-receptor-Toll-like receptor signaling through direct interaction with the adaptor Pellino-1".
TNIP2 (783 words) [view diff] exact match in snippet view article find links to article
polymerase II apoptotic process toll-like receptor 9 signaling pathway toll-like receptor 2 signaling pathway toll-like receptor 3 signaling pathway protein
Baculoviral IAP repeat-containing protein 3 (1,388 words) [view diff] exact match in snippet view article find links to article
heterooligomerization MyD88-independent toll-like receptor signaling pathway TRIF-dependent toll-like receptor signaling pathway negative regulation of
List of human clusters of differentiation (467 words) [view diff] exact match in snippet view article find links to article
Toll-like receptor 8 (TLR8); Genetic variants in TLR8 have recently been linked to susceptibility to pulmonary tuberculosis. CD289 Toll-like receptor
TNFAIP3 (1,971 words) [view diff] exact match in snippet view article find links to article
ubiquitin-dependent protein catabolic process negative regulation of toll-like receptor 2 signaling pathway negative regulation of nucleotide-binding oligomerization
Pinocembrin (279 words) [view diff] exact match in snippet view article find links to article
"Pinocembrin protects hemorrhagic brain primarily by inhibiting toll-like receptor 4 and reducing M1 phenotype microglia". Brain Behav. Immun. 61: 326–339
S100A9 (2,090 words) [view diff] exact match in snippet view article find links to article
together, MRP8 and MRP14 regulate myeloid cell function by binding to Toll-like receptor 4 (TLR4) and the receptor for advanced glycation end products. Intracellular
Bartonella quintana (1,481 words) [view diff] exact match in snippet view article find links to article
is its lipopolysaccharide covering which is an antagonist of the toll-like receptor 4. The reason this infection might persist is because this organism
Baculoviral IAP repeat-containing protein 2 (1,879 words) [view diff] exact match in snippet view article find links to article
acid-templated transcription MyD88-independent toll-like receptor signaling pathway TRIF-dependent toll-like receptor signaling pathway positive regulation of
Caspase 8 (2,275 words) [view diff] exact match in snippet view article find links to article
(NF-κB) after stimulation through antigen receptors, Fc receptors, or Toll-like receptor 4 in T, B, and natural killer cells. Biochemically, caspase-8 was
UBE2D1 (1,507 words) [view diff] exact match in snippet view article find links to article
cycle phase transition MyD88-independent toll-like receptor signaling pathway TRIF-dependent toll-like receptor signaling pathway Sources:Amigo / QuickGO
UBE2D2 (1,291 words) [view diff] exact match in snippet view article find links to article
stimulatory C-type lectin receptor signaling pathway TRIF-dependent toll-like receptor signaling pathway Fc-epsilon receptor signaling pathway protein K48-linked
UBE2D3 (1,253 words) [view diff] exact match in snippet view article find links to article
damage stimulus protein K11-linked ubiquitination TRIF-dependent toll-like receptor signaling pathway protein K48-linked ubiquitination regulation of
Depyrogenation (1,759 words) [view diff] case mismatch in snippet view article find links to article
monocytes). This monomerises the aggregated LPS, as the LPS receptor Toll-like Receptor 4 (TLR4) cannot recognise LPS while aggregated. Monomeric LPS is then
MAP3K7 (1,695 words) [view diff] exact match in snippet view article find links to article
NF-kappaB-inducing kinase activity I-kappaB phosphorylation MyD88-dependent toll-like receptor signaling pathway transcription, DNA-templated Fc-epsilon receptor
IKK2 (1,527 words) [view diff] exact match in snippet view article find links to article
signaling pathway T cell receptor signaling pathway TRIF-dependent toll-like receptor signaling pathway Fc-epsilon receptor signaling pathway positive regulation
IKBKG (3,277 words) [view diff] exact match in snippet view article find links to article
polyubiquitination of IRAK-1 is required for interleukin-1 receptor- and toll-like receptor-mediated NF-kappaB activation". Molecular and Cellular Biology. 28
IRAK3 (708 words) [view diff] exact match in snippet view article find links to article
to exogenous dsRNA protein phosphorylation negative regulation of toll-like receptor signaling pathway cytokine-mediated signaling pathway response to
TNIP3 (gene) (576 words) [view diff] exact match in snippet view article
"Expression of the NF-kappaB inhibitor ABIN-3 in response to TNF and toll-like receptor 4 stimulation is itself regulated by NF-kappaB". J. Cell. Mol. Med
Mariano Barbacid (641 words) [view diff] case mismatch in snippet view article find links to article
mammalian cyclin-dependent kinases and their inhibitors." (2000). "Toll-like Receptor-4 (TLR4) Down-regulates MicroRNA-107, Increasing Macrophage Adhesion
CD300LF (764 words) [view diff] exact match in snippet view article find links to article
negative regulation of MyD88-dependent toll-like receptor signaling pathway TRIF-dependent toll-like receptor signaling pathway interleukin-13-mediated
FUT7 (1,001 words) [view diff] exact match in snippet view article find links to article
A, Hesselberth JR, Fields S (March 2006). "Binding specificity of Toll-like receptor cytoplasmic domains". European Journal of Immunology. 36 (3): 742–53
IRF1 (1,861 words) [view diff] exact match in snippet view article find links to article
IFN-gamma-induced IFN regulatory factor 1 transcription factor by MyD88 in Toll-like receptor-dependent gene induction program". Proc. Natl. Acad. Sci. U.S.A. 103
Cathepsin K (1,710 words) [view diff] exact match in snippet view article find links to article
K, Kato S, Saftig P, Takayanagi H,. (2008). Cathepsin K-dependent toll-like receptor 9 signaling revealed in experimental arthritis. Science, 319(5863)
Glucuronic acid (1,879 words) [view diff] exact match in snippet view article find links to article
glucuronidated metabolite of ethanol, ethyl glucuronide (ETG), act on toll-like receptor 4 to aggravate both acute and chronic inflammatory conditions as well
Ubiquitin B (979 words) [view diff] exact match in snippet view article find links to article
positive regulation of protein monoubiquitination TRIF-dependent toll-like receptor signaling pathway Fc-epsilon receptor signaling pathway endosomal
Zymosan (191 words) [view diff] exact match in snippet view article find links to article
action. Sato M, Sano H, Iwaki D, et al. (2003). "Direct binding of Toll-like receptor 2 to zymosan, and zymosan-induced NF-kappa B activation and TNF-alpha
Nucleoside-modified messenger RNA (2,503 words) [view diff] exact match in snippet view article find links to article
barriers against foreign mRNA, such as innate immune system receptors, toll-like receptor (TLR) 7 and TLR8, located in endosomal membranes. RNA sensors like
Dirt (921 words) [view diff] exact match in snippet view article find links to article
LV; Schmidt, RR (22 November 2009), "Commensal bacteria regulate Toll-like receptor 3–dependent inflammation after skin injury", Nature Medicine, 15 (12):
Farnesoid X receptor (1,979 words) [view diff] exact match in snippet view article find links to article
glucose stimulus positive regulation of ammonia assimilation cycle toll-like receptor 4 signaling pathway immune system process histone H3-R17 methylation
TANK-binding kinase 1 (2,296 words) [view diff] exact match in snippet view article find links to article
transcription factors, NF-kappa B and IFN-regulatory factor-3, in the Toll-like receptor signaling". Journal of Immunology. 171 (8): 4304–4310. doi:10.4049/jimmunol
MAP3K7IP3 (604 words) [view diff] exact match in snippet view article find links to article
stimulatory C-type lectin receptor signaling pathway MyD88-dependent toll-like receptor signaling pathway Fc-epsilon receptor signaling pathway JNK cascade
Receptor modulator (982 words) [view diff] exact match in snippet view article find links to article
effect. Some common examples are opium derivates, such as heroin and Toll-like receptor agonists. Heroin functions in this manner, along with other opioids
Katalin Karikó (4,069 words) [view diff] exact match in snippet view article find links to article
Karikó; Drew Weissman; Frank A Welsh (1 November 2004). "Inhibition of toll-like receptor and cytokine signaling--a unifying theme in ischemic tolerance". Journal
IRF8 (2,321 words) [view diff] exact match in snippet view article find links to article
sequence-binding protein regulate the myeloid expression of the human Toll-like receptor 4 gene". J. Biol. Chem. 275 (13): 9773–81. doi:10.1074/jbc.275.13
Plasmacytoid dendritic cell (1,833 words) [view diff] exact match in snippet view article find links to article
HLA-DR, CD123, blood-derived dendritic cell antigen-2 (BDCA-2), Toll-like receptor (TLR) 7 and TLR9 within endosomal compartments. Expression of TLR
RIPK2 (962 words) [view diff] exact match in snippet view article find links to article
regulation of transcription by RNA polymerase II toll-like receptor 4 signaling pathway toll-like receptor 2 signaling pathway innate immune response MAPK
Gunther Hartmann (1,528 words) [view diff] exact match in snippet view article find links to article
he characterized the CpG motif in DNA that is detected by human Toll-like receptor 9 (TLR9) and then back in Munich he studied the immunobiological consequences
LILRA1 (499 words) [view diff] exact match in snippet view article find links to article
PMID 21388353. Pilsbury LE, Allen RL, Vordermeier M (2010). "Modulation of Toll-like receptor activity by leukocyte Ig-like receptors and their effects during bacterial
S100A14 (610 words) [view diff] exact match in snippet view article find links to article
antimicrobial protein of the skin: regulation by E. coli through Toll-like receptor 4". The Journal of Investigative Dermatology. 127 (11): 2596–604.
White-winged flufftail (1,239 words) [view diff] exact match in snippet view article find links to article
Antoinette Kotze (November 9, 2016). "Lack of diversity at innate immunity Toll-like receptor genes in the Critically Endangered White-winged Flufftail (Sarothrura
CD300A (571 words) [view diff] exact match in snippet view article find links to article
proliferation signal transduction negative regulation of MyD88-dependent toll-like receptor signaling pathway neutrophil degranulation Sources:Amigo / QuickGO
Nicotinamide (2,437 words) [view diff] exact match in snippet view article find links to article
has been shown to prevent Cutibacterium acnes-induced activation of toll-like receptor 2, which ultimately results in the down-regulation of pro-inflammatory
Ubiquitin C (4,261 words) [view diff] exact match in snippet view article find links to article
polyubiquitination of IRAK-1 is required for interleukin-1 receptor- and toll-like receptor-mediated NF-kappaB activation". Molecular and Cellular Biology. 28
Burghardt Wittig (2,139 words) [view diff] exact match in snippet view article find links to article
Scheithauer, W; Schmoll, HJ (2015). "MGN1703, an immunomodulator and toll-like receptor 9 (TLR-9) agonist: From bench to bedside". Crit Rev Oncol Haematol
FLOT1 (1,178 words) [view diff] exact match in snippet view article find links to article
regulation of toll-like receptor 4 signaling pathway positive regulation of heterotypic cell-cell adhesion positive regulation of toll-like receptor 3 signaling
S100A8 (1,048 words) [view diff] exact match in snippet view article find links to article
Gene ontology Molecular function Toll-like receptor 4 binding RAGE receptor binding microtubule binding protein binding calcium ion binding arachidonic
CHUK (2,736 words) [view diff] exact match in snippet view article find links to article
response to hydroperoxide response to organic substance TRIF-dependent toll-like receptor signaling pathway Fc-epsilon receptor signaling pathway protein phosphorylation
MBL deficiency (890 words) [view diff] exact match in snippet view article find links to article
Zhengliang (March 7, 2011). "Mannan-binding lectin directly interacts with Toll-like receptor 4 and suppresses lipopolysaccharide-induced inflammatory cytokine
Septic shock (3,539 words) [view diff] exact match in snippet view article find links to article
as 10 pg/mL) results in intracellular signaling via an associated "Toll-like receptor" protein 4 (TLR-4). This signaling results in the activation of nuclear
PIK3R4 (561 words) [view diff] exact match in snippet view article find links to article
transduction pathways mediated by the interaction of CpG DNA with Toll-like receptor 9". Semin. Immunol. 16 (1): 17–22. doi:10.1016/j.smim.2003.10.009
Granule (cell biology) (1,226 words) [view diff] exact match in snippet view article
hexosaminidase. An electron-dense granule defined by the presence of Toll-like receptor 9 (TLR9) and protein disulfide isomerase (PDI), termed the T granule
Cefodizime (625 words) [view diff] exact match in snippet view article find links to article
was shown in a 2004 study that cefodizime increased expression of toll-like receptor 4 (TLR-4) in neutrophils stimulated by Klebsiella pneumoniae infection
TRAF1 (2,025 words) [view diff] exact match in snippet view article find links to article
Watts TH (2017). "The signaling adaptor TRAF1 negatively regulates Toll-like receptor signaling and this underlies its role in rheumatic disease". Nature
FAM114A1 (721 words) [view diff] exact match in snippet view article find links to article
chromosome: TLR1: Toll-like receptor (TLR) 1 plays a role in pathogen recognition and activation of innate immunity. TLR6: Toll-like receptor (TLR) 6 plays
CD180 (790 words) [view diff] exact match in snippet view article find links to article
cell proliferation involved in immune response immune system process toll-like receptor signaling pathway inflammatory response Sources:Amigo / QuickGO
Andreas Peschel (737 words) [view diff] exact match in snippet view article find links to article
Macek B, Wolz C, Götz F, Otto M, Kretschmer D, Peschel A. 2016. “Toll-like receptor 2 activation depends on lipopeptide shedding by bacterial surfactants
HAVCR2 (2,900 words) [view diff] exact match in snippet view article find links to article
presenting cell negative regulation of tumor necrosis factor production toll-like receptor 9 signaling pathway negative regulation of type I interferon production
DAB2IP (861 words) [view diff] exact match in snippet view article find links to article
regulatory subunit binding phosphatidylinositol-4-phosphate binding Toll-like receptor 4 binding kinase binding protein phosphatase 2A binding mitogen-activated
CD86 (3,221 words) [view diff] exact match in snippet view article find links to article
cytokine stimulus T cell proliferation involved in immune response toll-like receptor signaling pathway positive regulation of transcription, DNA-templated
LILRA2 (697 words) [view diff] exact match in snippet view article find links to article
interleukin-6 production interleukin-8 production negative regulation of toll-like receptor 4 signaling pathway granulocyte colony-stimulating factor production
TRAF3 (2,200 words) [view diff] exact match in snippet view article find links to article
process Toll signaling pathway immune system process TRIF-dependent toll-like receptor signaling pathway protein ubiquitination negative regulation of NF-kappaB
TRAP1 (787 words) [view diff] exact match in snippet view article find links to article
Brown V, Brown RA, Ozinsky A, et al. (2006). "Binding specificity of Toll-like receptor cytoplasmic domains". Eur. J. Immunol. 36 (3): 742–53. doi:10.1002/eji
NLRP6 (325 words) [view diff] exact match in snippet view article find links to article
of immune response regulation of autophagy negative regulation of toll-like receptor signaling pathway negative regulation of inflammatory response to
FAM185A (769 words) [view diff] exact match in snippet view article find links to article
FAM185a expression is greatly decreased in ROR1-alpha knockout mice and toll-like receptor 5 knockout mice. Mice also show a decrease in FAM185a expression in
FADD (4,191 words) [view diff] exact match in snippet view article find links to article
SM, Pope RM (2004). "Fas ligation on macrophages enhances IL-1R1-Toll-like receptor 4 signaling and promotes chronic inflammation". Nature Immunology
Viperin (1,413 words) [view diff] exact match in snippet view article find links to article
activation immune system process response to virus positive regulation of toll-like receptor 7 signaling pathway negative regulation of viral genome replication
PPAR agonist (1,030 words) [view diff] case mismatch in snippet view article find links to article
"Targeting the Toll of Drug Abuse: The Translational Potential of Toll-Like Receptor 4". CNS & Neurological Disorders Drug Targets. 14 (6): 692–9. doi:10
MAP3K7IP2 (1,677 words) [view diff] exact match in snippet view article find links to article
M, Nie H, Silva AM, Williams BR, Li X (2003). "Poly(I-C)-induced Toll-like receptor 3 (TLR3)-mediated activation of NFkappa B and MAP kinase is through
TYRO3 (962 words) [view diff] exact match in snippet view article find links to article
cellular homeostasis protein kinase B signaling negative regulation of toll-like receptor signaling pathway secretion by cell negative regulation of inflammatory
Cell–cell recognition (2,047 words) [view diff] no match in snippet view article find links to article
Marta; Zhao, Lue Ping; Kaplan, Gilla; Aderem, Alan (15 January 2008). "TollLike Receptor 2 (TLR2) Polymorphisms Are Associated with Reversal Reaction in Leprosy"
Beth Mallard (299 words) [view diff] exact match in snippet view article find links to article
Times. Retrieved 10 July 2014. Mallard, Beth (2011). The role of Toll-like receptor 4 in Concanavalin A-induced immune-mediated hepatitis (Doctoral thesis)
CLEC10A (1,300 words) [view diff] case mismatch in snippet view article find links to article
Specific Marker for Human CD1c+ Dendritic Cells and Enhances Their Toll-Like Receptor 7/8-Induced Cytokine Secretion". Frontiers in Immunology. 9: 744.
Spontaneous remission (1,064 words) [view diff] exact match in snippet view article find links to article
has a shiga toxin-like structure and should be combined with other Toll-like receptor ligands in cancer therapy" (PDF). Cancer Immunology, Immunotherapy
RGC100 (79 words) [view diff] case mismatch in snippet view article find links to article
Rohayem, Jacques (2013). "Activation of Dendritic Cells by the Novel Toll-Like Receptor 3 Agonist RGC100". Clinical and Developmental Immunology. 2013: 283649
DUSP1 (1,177 words) [view diff] exact match in snippet view article find links to article
enhances nontypeable Haemophilus influenzae-induced expression of toll-like receptor 2". The Journal of Biological Chemistry. 277 (49): 47444–50. doi:10
RG7795 (196 words) [view diff] exact match in snippet view article find links to article
Bhagchandani, Jeremiah A.Johnson, and Darrell J.Irvine (2021). "Evolution of Toll-like receptor 7/8 agonist therapeutics and their delivery approaches: From antiviral
Immune complex (1,112 words) [view diff] exact match in snippet view article find links to article
Michelle R.; Gosselin, Edmund J. (November 2019). "Fcγ receptors and toll-like receptor 9 synergize to drive immune complex-induced dendritic cell maturation"
Fibrinogen alpha chain (1,087 words) [view diff] exact match in snippet view article find links to article
transduction induction of bacterial agglutination platelet activation toll-like receptor signaling pathway post-translational protein modification Sources:Amigo
Non-celiac gluten sensitivity (7,551 words) [view diff] exact match in snippet view article find links to article
part of the plant's natural defence against insects and may cause toll-like receptor 4 (TLR4)-mediated intestinal inflammation in humans. These TLR4-stimulating
RPS6KA3 (1,380 words) [view diff] exact match in snippet view article find links to article
transduction positive regulation of transcription by RNA polymerase II toll-like receptor signaling pathway apoptotic process peptidyl-serine phosphorylation
Galectin-9 (2,159 words) [view diff] exact match in snippet view article find links to article
regulation of interferon-gamma production response to interleukin-1 toll-like receptor 4 signaling pathway maternal process involved in female pregnancy
PTPN22 (3,898 words) [view diff] exact match in snippet view article find links to article
regulation of natural killer cell proliferation positive regulation of toll-like receptor 3 signaling pathway regulation of T cell receptor signaling pathway
Integrin beta 2 (1,299 words) [view diff] exact match in snippet view article find links to article
process leukocyte cell-cell adhesion endodermal cell differentiation toll-like receptor 4 signaling pathway positive regulation of nitric oxide biosynthetic
Xanthan gum (1,882 words) [view diff] exact match in snippet view article find links to article
administration of xanthan gum enhances antitumor activity through Toll-like receptor 4". International Immunopharmacology. 9 (13–14): 1562–1567. doi:10
LYN (3,789 words) [view diff] exact match in snippet view article find links to article
migration ephrin receptor signaling pathway negative regulation of toll-like receptor 2 signaling pathway T cell costimulation response to peptide hormone
Gluten (6,771 words) [view diff] exact match in snippet view article find links to article
fibromyalgia, psychological disturbances, and dermatitis. ATIs may cause toll-like receptor 4 (TLR4)-mediated intestinal inflammation in humans. People can also
IKBKE (1,381 words) [view diff] exact match in snippet view article find links to article
interferon-beta cellular response to DNA damage stimulus TRIF-dependent toll-like receptor signaling pathway protein phosphorylation response to type I interferon
William Paul Duprex (2,008 words) [view diff] exact match in snippet view article find links to article
e1001263. Ligand-induced conformational changes allosterically activate Toll-like receptor 9 (2007). Nature immunology, 8 (7), 772–779. Predominant Infection
MAPKAPK3 (1,042 words) [view diff] exact match in snippet view article find links to article
peptidyl-serine phosphorylation protein autophosphorylation signal transduction toll-like receptor signaling pathway MAPK cascade intracellular signal transduction Sources:Amigo
PELI2 (391 words) [view diff] exact match in snippet view article find links to article
Dong W, Chen L, et al. (2004). "BCL10 mediates lipopolysaccharide/toll-like receptor-4 signaling through interaction with Pellino2". J. Biol. Chem. 279
Melanocyte (2,262 words) [view diff] no match in snippet view article find links to article
response to activation of Pattern Recognition Receptors (PRRs) such as Toll Like Receptor 4 (TLR4) which recognize MAMPs. MAMPs, also known as PAMPs, are microbial
PTPRS (1,380 words) [view diff] exact match in snippet view article find links to article
negative regulation of interferon-beta production negative regulation of toll-like receptor 9 signaling pathway negative regulation of neuron projection development
GFI1 (1,256 words) [view diff] exact match in snippet view article find links to article
development regulation of transcription, DNA-templated regulation of toll-like receptor signaling pathway regulation of histone H3-K4 methylation negative
Polyporus umbellatus (440 words) [view diff] exact match in snippet view article find links to article
activation and maturation of murine bone-derived dendritic cells via toll-like receptor 4". Cell Immunol. 265 (1): 50–6. doi:10.1016/j.cellimm.2010.07.002
Acute-phase protein (1,096 words) [view diff] exact match in snippet view article find links to article
of CD14 and lipopolysaccharide-binding protein for activation of toll-like receptor (TLR)2 as well as TLR4 Reconstitution of TLR2- and TLR4-activation
Imiquimod (1,712 words) [view diff] exact match in snippet view article find links to article
synergistically. Imiquimod stimulates the innate immune system by activating toll-like receptor 7 (TLR7), commonly involved in pathogen recognition. Cells activated
Coxsackie B virus (1,879 words) [view diff] exact match in snippet view article find links to article
arrhythmia. Studies in mice suggest that CB3 enters cells by means of toll-like receptor 4. Both CB3 and CB4 exploit cellular autophagy to promote replication
PJA2 (502 words) [view diff] exact match in snippet view article find links to article
protein ubiquitination inflammatory response positive regulation of toll-like receptor 2 signaling pathway regulation of macrophage activation innate immune
TRAFD1 (515 words) [view diff] exact match in snippet view article find links to article
interferon- and LPS-inducible gene acting as a negative regulator of toll-like receptor signaling". J. Biol. Chem. 280 (50): 41289–97. doi:10.1074/jbc.M508221200
Antigen (2,435 words) [view diff] exact match in snippet view article find links to article
(December 2006). "Adjuvant-enhanced antibody responses in the absence of toll-like receptor signaling". Science. 314 (5807): 1936–1938. Bibcode:2006Sci...314
IL17RD (1,360 words) [view diff] exact match in snippet view article find links to article
Wurst W, et al. (March 2015). "Orphan receptor IL-17RD regulates Toll-like receptor signalling via SEFIR/TIR interactions". Nature Communications. 6 (1):
MAP3K2 (1,517 words) [view diff] exact match in snippet view article find links to article
"Identification of MEKK2/3 serine phosphorylation site targeted by the Toll-like receptor and stress pathways". The EMBO Journal. 25 (1): 97–107. doi:10.1038/sj
CpG site (5,483 words) [view diff] exact match in snippet view article find links to article
chimpanzees. Unmethylated CpG dinucleotide sites can be detected by Toll-like receptor 9 (TLR 9) on plasmacytoid dendritic cells, monocytes, natural killer
IκBα (1,526 words) [view diff] exact match in snippet view article find links to article
transcription by RNA polymerase II apoptotic process liver regeneration toll-like receptor 4 signaling pathway protein deubiquitination I-kappaB kinase/NF-kappaB
Flufftail (971 words) [view diff] exact match in snippet view article find links to article
Kotze, Antoinette (2016-11-09). "Lack of diversity at innate immunity Toll-like receptor genes in the Critically Endangered White-winged Flufftail (Sarothrura
Chronic pulmonary aspergillosis (2,907 words) [view diff] exact match in snippet view article find links to article
of developing chronic pulmonary aspergillosis, such as defects to toll-like receptor (TLR) 4, IL1 and IL15, TLR3, TLR10, TREM1, VEGFA, DENND1B, and PLAT
Kupffer cell (1,861 words) [view diff] exact match in snippet view article find links to article
injury. The cascade begins with endotoxin-mediated activation of the Toll-like receptor 4 (TLR4) and CD14, receptors on the Kupffer cell that internalize
IFI16 (1,371 words) [view diff] exact match in snippet view article find links to article
Caneparo V, Raviola S, Debernardi I, Colangelo D, et al. (2020) Toll-like receptor 4-mediated inflammation triggered by extracellular IFI16 is enhanced
IRF5 (1,566 words) [view diff] exact match in snippet view article find links to article
"The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling". J. Biol. Chem. 280 (17): 17005–12. doi:10.1074/jbc.M412584200
Cathepsin B (1,346 words) [view diff] exact match in snippet view article find links to article
of apoptotic process epithelial cell differentiation proteolysis toll-like receptor signaling pathway decidualization cellular response to thyroid hormone
Roman Dziarski (5,581 words) [view diff] exact match in snippet view article find links to article
"Peptidoglycan- and lipoteichoic acid-induced cell activation is mediated by toll-like receptor 2". The Journal of Biological Chemistry. 274 (25): 17406–17409. doi:10
APPL2 (415 words) [view diff] exact match in snippet view article find links to article
migration signaling adiponectin-activated signaling pathway regulation of toll-like receptor 4 signaling pathway cellular response to hepatocyte growth factor
Fibrinogen gamma chain (471 words) [view diff] exact match in snippet view article find links to article
adhesion platelet aggregation signal transduction platelet activation toll-like receptor signaling pathway platelet maturation cellular response to interleukin-1
Caveolin 1 (1,551 words) [view diff] exact match in snippet view article find links to article
to transforming growth factor beta stimulus positive regulation of toll-like receptor 3 signaling pathway regulation of cytosolic calcium ion concentration
MAP3K3 (1,820 words) [view diff] exact match in snippet view article find links to article
(Jan 2004). "Differential regulation of interleukin 1 receptor and Toll-like receptor signaling by MEKK3". Nature Immunology. 5 (1): 98–103. doi:10.1038/ni1014
Phytolacca americana (4,213 words) [view diff] case mismatch in snippet view article find links to article
Parcina, Marijo; Heeg, Klaus (2012-01-04). "Poke Weed Mitogen Requires Toll-Like Receptor Ligands for Proliferative Activity in Human and Murine B Lymphocytes"
Serum amyloid A1 (4,261 words) [view diff] exact match in snippet view article find links to article
2009). "Serum amyloid A induces G-CSF expression and neutrophilia via Toll-like receptor 2". Blood. 113 (2): 429–37. doi:10.1182/blood-2008-03-139923. PMC 2615655
Cathepsin L1 (1,689 words) [view diff] exact match in snippet view article find links to article
antigen via MHC class II extracellular matrix disassembly proteolysis toll-like receptor signaling pathway cellular response to thyroid hormone stimulus collagen
OTUD4 (649 words) [view diff] exact match in snippet view article find links to article
deubiquitination proteolysis immune system process negative regulation of toll-like receptor signaling pathway innate immune response protein K63-linked deubiquitination
AOAH (802 words) [view diff] case mismatch in snippet view article find links to article
non-stimulatory and can be a potent inhibitor of LPS sensing via the MD-2--Toll-like Receptor 4 (TLR4). The enzyme's other known substrates include bacterial lipopeptides
Interleukin 23 (2,192 words) [view diff] exact match in snippet view article find links to article
PMC 1782263. PMID 16630024. Re F, Strominger JL (October 2001). "Toll-like receptor 2 (TLR2) and TLR4 differentially activate human dendritic cells".
G. Dhinakar Raj (1,286 words) [view diff] exact match in snippet view article find links to article
Dhanasekaran, S.; Tirumurugaan, K.G.; Raja, A. (2012). "Comparative in vitro toll-like receptor ligand induced cytokine profiles of Toda and Murrah buffaloes—Identification
G. Dhinakar Raj (1,286 words) [view diff] exact match in snippet view article find links to article
Dhanasekaran, S.; Tirumurugaan, K.G.; Raja, A. (2012). "Comparative in vitro toll-like receptor ligand induced cytokine profiles of Toda and Murrah buffaloes—Identification
PIK3C3 (901 words) [view diff] exact match in snippet view article find links to article
endosome transport phosphatidylinositol biosynthetic process cell cycle toll-like receptor 9 signaling pathway macroautophagy regulation of protein secretion
Richard Bonneau (880 words) [view diff] exact match in snippet view article find links to article
Smith KD, Bonneau R, Strong RK, Aderem A. A conserved surface on Toll-like receptor 5 recognizes bacterial flagellin. (2007) J Exp Med. Feb 19;204(2):393-403
GRAMD4 (240 words) [view diff] exact match in snippet view article find links to article
cysteine-type endopeptidase activity involved in apoptotic process negative regulation of toll-like receptor 9 signaling pathway Sources:Amigo / QuickGO
Neuroimmunology (2,716 words) [view diff] no match in snippet view article find links to article
be linked to inflammatory markers. Studies have demonstrated that Toll like-receptor (TLR4) is critically involved in neuroinflammation and T cell recruitment
NLRP12 (1,230 words) [view diff] exact match in snippet view article find links to article
et al. (2006). "The CATERPILLER protein monarch-1 is an antagonist of toll-like receptor-, tumor necrosis factor alpha-, and Mycobacterium tuberculosis-induced
Liver X receptor alpha (1,699 words) [view diff] exact match in snippet view article find links to article
complex nucleus cytoplasm Biological process positive regulation of toll-like receptor 4 signaling pathway sterol homeostasis negative regulation of pancreatic
TRIL (gene) (541 words) [view diff] exact match in snippet view article
involved in immune response innate immune response inflammatory response toll-like receptor 4 signaling pathway immune system process Sources:Amigo / QuickGO
Dermatomyositis (2,794 words) [view diff] exact match in snippet view article find links to article
adrenocorticotropic hormone gel (Phase IV, open label), IMO-8400, an antagonist of Toll-like receptor 7,8 and 9 (Ph II), abatacept (Phase IV, open label), and sodium thiosulfate
Death receptor 3 (1,588 words) [view diff] case mismatch in snippet view article find links to article
in antigen presenting cells and some endothelial cells following Toll-Like Receptor or Fc receptor activation. This receptor has been shown to signal
Daniel J. Drucker (1,905 words) [view diff] exact match in snippet view article find links to article
2024). "Central glucagon-like peptide 1 receptor activation inhibits Toll-like receptor agonist-induced inflammation". Cell Metabolism. 36 (1): 130–143.e5
OSCAR (gene) (583 words) [view diff] exact match in snippet view article
induces survival and maturation of dendritic cells and modulates Toll-like receptor responses". Blood. 105 (9): 3623–32. doi:10.1182/blood-2004-07-2809
LUC7L3 (644 words) [view diff] exact match in snippet view article find links to article
Brown V, Brown RA, Ozinsky A, et al. (2006). "Binding specificity of Toll-like receptor cytoplasmic domains". Eur. J. Immunol. 36 (3): 742–53. doi:10.1002/eji
Collectin-12 (593 words) [view diff] exact match in snippet view article find links to article
exogenous dsRNA phagocytosis, recognition innate immune response toll-like receptor 3 signaling pathway protein homooligomerization regulation of immune
CYP1A1 (1,835 words) [view diff] case mismatch in snippet view article find links to article
intestine, but not the liver, CYP1A1 expression moreover depends on TOLL-like receptor 2 (TLR2), which recognizes bacterial surface structures such as lipoteichoic
Tivadar Tulassay (326 words) [view diff] exact match in snippet view article find links to article
the rat kidney (co-author, 2004) Increased mucosal expression of Toll-like receptor (TLR)2 and TLR4 in coeliac disease (co-author, 2007) Index: Lemond
T helper 3 cell (1,235 words) [view diff] exact match in snippet view article find links to article
(transforming growth factor-β1) expression on CD4+ T cells reduces Toll-like receptor 4 ligand-induced tumour necrosis factor-α production in a transforming
F8A1 (791 words) [view diff] exact match in snippet view article find links to article
Ozinsky A, Hesselberth JR, Fields S (2006). "Binding specificity of Toll-like receptor cytoplasmic domains". Eur. J. Immunol. 36 (3): 742–53. doi:10.1002/eji
Altered Schaedler flora (2,579 words) [view diff] exact match in snippet view article find links to article
maturation of lymphoid follicles into large B cell clusters by the toll-like receptor signaling. In another study, the innate detection system generates
P38 mitogen-activated protein kinases (1,385 words) [view diff] exact match in snippet view article find links to article
key regulator of proinflammatory cytokine up-regulation induced by toll-like receptor (TLR) ligands or beta-amyloid (Aβ)". Journal of Neuroinflammation
RAB11FIP2 (1,023 words) [view diff] exact match in snippet view article find links to article
protein localization to plasma membrane phagocytosis TRAM-dependent toll-like receptor 4 signaling pathway positive regulation of GTPase activity Sources:Amigo
Bruton's tyrosine kinase (2,210 words) [view diff] exact match in snippet view article find links to article
phosphorylation negative regulation of cytokine production MyD88-dependent toll-like receptor signaling pathway apoptotic signaling pathway calcium-mediated signaling
MAPKAPK2 (1,839 words) [view diff] exact match in snippet view article find links to article
response macropinocytosis regulation of tumor necrosis factor production toll-like receptor signaling pathway intracellular signal transduction Sources:Amigo
Electrospray (1,951 words) [view diff] case mismatch in snippet view article find links to article
2174/1573413052953192. Duong, A.D. (2013). "Electrospray Encapsulation of Toll-Like Receptor Agonist Resiquimod in Polymer Microparticles for the Treatment of
Fungal immunomodulatory protein (633 words) [view diff] exact match in snippet view article find links to article
2009). "A novel immunomodulatory protein from Poria cocos induces Toll-like receptor 4-dependent activation within mouse peritoneal macrophages". Journal
LGR4 (294 words) [view diff] exact match in snippet view article find links to article
osteoblast differentiation bone mineralization negative regulation of toll-like receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor
List of withdrawn drugs (1,956 words) [view diff] exact match in snippet view article find links to article
Bhagchandani, Jeremiah A.Johnson, and Darrell J.Irvine (2021). "Evolution of Toll-like receptor 7/8 agonist therapeutics and their delivery approaches: From antiviral
Novimmune (361 words) [view diff] case mismatch in snippet view article find links to article
- Bloomberg". www.bloomberg.com. "First in Human Study of an Anti-Toll-like Receptor 4 (TLR4) Monoclonal Antibody (NI-0101) in Adult Healthy Volunteers
Alloimmunity (2,381 words) [view diff] exact match in snippet view article find links to article
WE, Goldstein DR (August 2007). "Neonatal B cells suppress innate toll-like receptor immune responses and modulate alloimmunity". J. Immunol. 179 (3):
RAB11A (1,390 words) [view diff] exact match in snippet view article find links to article
TE, Bakke O, Espevik T (October 2010). "The Rab11a GTPase controls Toll-like receptor 4-induced activation of interferon regulatory factor-3 on phagosomes"
Ischemic preconditioning (1,235 words) [view diff] exact match in snippet view article find links to article
LN, Zhu W, Li Y, Xu XL, Guo LJ, Lu Q, Wang J (2014). "Astrocytic Toll-like receptor 3 is associated with ischemic preconditioning-induced protection against
IRF4 (2,598 words) [view diff] exact match in snippet view article find links to article
DNA-templated peptidyl-lysine methylation negative regulation of toll-like receptor signaling pathway type I interferon signaling pathway histone H3 acetylation
UBQLN1 (1,428 words) [view diff] exact match in snippet view article find links to article
positive regulation of protein ubiquitination negative regulation of toll-like receptor 3 signaling pathway cellular response to hypoxia autophagosome maturation
Benzo(a)pyrene (2,659 words) [view diff] case mismatch in snippet view article
circulation. Intestinal, but not hepatic, expression of CYP1A1 depends on TOLL-like receptor 2 (TLR2), which is a eukaryotic receptor for bacterial surface structures
Tyrosine-protein kinase SYK (2,083 words) [view diff] exact match in snippet view article find links to article
activity protein kinase binding nucleotide binding phosphatase binding Toll-like receptor binding phosphotyrosine residue binding SH2 domain binding interleukin-15
BCL10 (1,813 words) [view diff] exact match in snippet view article find links to article
signaling pathway negative regulation of mature B cell apoptotic process toll-like receptor signaling pathway positive regulation of transcription, DNA-templated
UBQLN1 (1,428 words) [view diff] exact match in snippet view article find links to article
positive regulation of protein ubiquitination negative regulation of toll-like receptor 3 signaling pathway cellular response to hypoxia autophagosome maturation
Spliceman (1,092 words) [view diff] case mismatch in snippet view article find links to article
"AP1S3 Mutations Are Associated with Pustular Psoriasis and Impaired Toll-like Receptor 3 Trafficking". American Journal of Human Genetics. 94 (5): 790–797
Dipyaman Ganguly (1,502 words) [view diff] case mismatch in snippet view article find links to article
(May 2020). "A Chemical Switch for Transforming a Purine Agonist for Toll-like Receptor 7 to a Clinically Relevant Antagonist". Journal of Medicinal Chemistry
Clindamycin/benzoyl peroxide (1,473 words) [view diff] exact match in snippet view article find links to article
"Review of the innate immune response in acne vulgaris: activation of Toll-like receptor 2 in acne triggers inflammatory cytokine responses". Dermatology.
Nventa Biopharmaceuticals Corporation (803 words) [view diff] exact match in snippet view article find links to article
specific diseases. Nventa is developing HspE7 in combination with the Toll-like receptor 3 (TLR3) agonist adjuvant Poly-ICLC for multiple indications, including
Tretinoin (2,940 words) [view diff] exact match in snippet view article find links to article
involved in inflammation. Retinoids also down-regulate expression of toll-like receptor (TLR)-2, which has been implicated in the inflammatory response in
Burkholderia mallei (2,962 words) [view diff] case mismatch in snippet view article find links to article
"Structural Relationship of the Lipid A Acyl Groups to Activation of Murine Toll-Like Receptor 4 by Lipopolysaccharides from Pathogenic Strains of Burkholderia mallei
RIPK3 (948 words) [view diff] exact match in snippet view article find links to article
Kelliher M, Tschopp J (May 2004). "RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B activation" (PDF). Nature Immunology. 5 (5):
Hermann Wagner (880 words) [view diff] exact match in snippet view article find links to article
March 2004). "Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8". Science. 303 (5663): 1526–1529. Bibcode:2004Sci...303.1526H
LGMN (771 words) [view diff] exact match in snippet view article find links to article
vacuolar protein processing receptor catabolic process proteolysis toll-like receptor signaling pathway proteolysis involved in cellular protein catabolic
Mihai Netea (2,194 words) [view diff] exact match in snippet view article find links to article
Diet and Health" (400.000 euro) EP2076282 – Novel antagonists of the Toll-like receptor 4. EP6030245 - Novel method for diagnosing Lyme disease using a cellular
Cathepsin S (2,251 words) [view diff] exact match in snippet view article find links to article
II protein processing extracellular matrix disassembly proteolysis toll-like receptor signaling pathway antigen processing and presentation of peptide antigen
GPS2 (gene) (1,333 words) [view diff] exact match in snippet view article
lipid metabolic process B cell differentiation negative regulation of toll-like receptor signaling pathway positive regulation of peroxisome proliferator activated
Interleukin 26 (2,809 words) [view diff] exact match in snippet view article find links to article
type I interferon by plasmacytoid dendritic cells via activation of Toll-like receptor 9, but independently of the IL-26 receptor. Monocytes infected with
CD300LB (gene) (411 words) [view diff] case mismatch in snippet view article
(June 2016). "Lipopolysaccharide-Induced CD300b Receptor Binding to Toll-like Receptor 4 Alters Signaling to Drive Cytokine Responses that Enhance Septic
CD19 (3,948 words) [view diff] exact match in snippet view article find links to article
Conley ME, Reisli I, Franco JL, Meffre E (March 2016). "CD19 controls Toll-like receptor 9 responses in human B cells". The Journal of Allergy and Clinical
Arrestin beta 2 (1,958 words) [view diff] exact match in snippet view article find links to article
development negative regulation of GTPase activity negative regulation of toll-like receptor signaling pathway protein ubiquitination positive regulation of DNA
MAP3K1 (3,167 words) [view diff] exact match in snippet view article find links to article
cytoplasm cytosol Biological process phosphorylation MyD88-dependent toll-like receptor signaling pathway Fc-epsilon receptor signaling pathway protein phosphorylation
CD200R1 (1,187 words) [view diff] exact match in snippet view article find links to article
impaired in membrane glycoprotein CD200-deficient mice: a role for Toll-like receptor activation". The Journal of Biological Chemistry. 286 (40): 34722–32
APPL1 (1,166 words) [view diff] exact match in snippet view article find links to article
migration signaling adiponectin-activated signaling pathway regulation of toll-like receptor 4 signaling pathway cellular response to hepatocyte growth factor
Fibrinogen beta chain (972 words) [view diff] exact match in snippet view article find links to article
aggregation signal transduction induction of bacterial agglutination platelet activation toll-like receptor signaling pathway Sources:Amigo / QuickGO
Mitochondrial biogenesis (2,583 words) [view diff] exact match in snippet view article find links to article
(February 2015). "Suppression of mitochondrial biogenesis through toll-like receptor 4-dependent mitogen-activated protein kinase kinase/extracellular
Katherine A. Fitzgerald (907 words) [view diff] exact match in snippet view article find links to article
McMurray, Diane (2001). "Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction". Nature. 413 (6851): 78–83. Bibcode:2001Natur
TANK (gene) (1,420 words) [view diff] exact match in snippet view article
cytosol protein-containing complex Biological process TRIF-dependent toll-like receptor signaling pathway signal transduction positive regulation of ubiquitin-specific
Burkitt lymphoma (4,423 words) [view diff] exact match in snippet view article find links to article
reactivation of latent EBV and also MYC translocations via activation of the toll-like receptor 9. Malaria also promotes B-cell proliferation by altering the regular
Statera BioPharma (858 words) [view diff] case mismatch in snippet view article find links to article
process for human pharmaceuticals. Entolimod acts through activation of Toll-like Receptor 5 to mobilize antitumor immune response and reduce radiation effects
Sarcoidosis (12,895 words) [view diff] exact match in snippet view article find links to article
Crouser ED (February 2013). "Nicotine treatment improves Toll-like receptor 2 and Toll-like receptor 9 responsiveness in active pulmonary sarcoidosis". Chest
Curli (1,701 words) [view diff] case mismatch in snippet view article find links to article
is recognized in the innate immune system and activates the TLR2 (Toll-Like Receptor 2). This then causes a downstream response by producing a pro-inflammatory
NOX2 (2,434 words) [view diff] case mismatch in snippet view article find links to article
Inflammation and Hypotension in Endotoxemia by Controlling Expression of Toll-Like Receptor 4". Shock. 56 (2): 268–277. doi:10.1097/SHK.0000000000001706. PMC 8284354
Major histocompatibility complex and sexual selection (4,280 words) [view diff] exact match in snippet view article find links to article
Tschirren, Barbara (2014-08-01). "Naturally occurring Toll-like receptor 11 (TLR11) and Toll-like receptor 12 (TLR12) polymorphisms are not associated with
Catastrophic antiphospholipid syndrome (1,425 words) [view diff] exact match in snippet view article find links to article
favors a hypercoagulable state, which has been noted to activate toll-like receptor 4 resulting in what is known as a cytokine storm or a thrombotic storm
Douglas R. Green (954 words) [view diff] exact match in snippet view article find links to article
M; Tanaka, K; Cleveland, J. L.; Withoff, S; Green, D. R. (2007). "Toll-like receptor signalling in macrophages links the autophagy pathway to phagocytosis"
Mannose receptor (3,682 words) [view diff] exact match in snippet view article find links to article
HEK 293 cells co-transfected with human mannose receptor and human Toll-like receptor 2 cDNA are able to secrete IL-8 in response to P. carinii infection
Apilimod (658 words) [view diff] exact match in snippet view article find links to article
the small molecular IL-12/IL-23 inhibitor apilimod and a player in Toll-like receptor signaling". Chemistry & Biology. 20 (7): 912–21. doi:10.1016/j.chembiol
(+)-Benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide (1,494 words) [view diff] case mismatch in snippet view article
circulation. Intestinal, but not hepatic, expression of CYP1A1 depends on TOLL-like receptor 2 (TLR2), which is a eucaryotic receptor for bacterial surface structures
Mitochondrial antiviral-signaling protein (1,918 words) [view diff] exact match in snippet view article find links to article
Double stranded RNA viruses are recognized by either the transmembrane toll-like receptor 3 (TLR3) or by one of two cytosolic proteins, retinoic acid-inducible
Caspase 1 (2,389 words) [view diff] exact match in snippet view article find links to article
Balosso S, Sanchez MA, Bartfai T (October 2011). "IL-1 receptor/Toll-like receptor signaling in infection, inflammation, stress and neurodegeneration
Mollaret's meningitis (1,601 words) [view diff] case mismatch in snippet view article find links to article
Ahmad-Nejad; Michael Neumaier; Michael G. Hennerici; Marc Fatar (2010). "Toll-Like Receptor 3 Immune Deficiency May Be Causative for HSV-2-Associated Mollaret
Noscapine (2,870 words) [view diff] exact match in snippet view article find links to article
effects than noscapine. Again, this brominated derivative also inhibits toll-like receptor (TLR), tumour necrosis factor α (TNF-α), and NO in human and mous
Surfactant protein D (1,678 words) [view diff] exact match in snippet view article find links to article
immune response lung alveolus development innate immune response toll-like receptor signaling pathway induction of bacterial agglutination regulation
S100-A1 (4,914 words) [view diff] exact match in snippet view article find links to article
released from ischemic cardiomyocytes and signals myocardial damage via Toll-like receptor 4". EMBO Molecular Medicine. 6 (6): 778–94. doi:10.15252/emmm.201303498
HDAC7 (2,069 words) [view diff] exact match in snippet view article find links to article
KM, Fairlie DP, Sweet MJ (2013). "Histone deacetylase 7 promotes Toll-like receptor 4-dependent proinflammatory gene expression in macrophages". The Journal
NFKBIZ (1,238 words) [view diff] exact match in snippet view article find links to article
lipopolysaccharide induces mRNA expression of an IkappaB MAIL through toll-like receptor 4". The Journal of Veterinary Medical Science. 64 (5): 419–22. doi:10
Adeno-associated virus (8,517 words) [view diff] exact match in snippet view article find links to article
longer. In-vivo studies indicate that AAV vectors interact with the Toll-like receptor (TLR)9- and TLR2-MyD88 pathways to trigger the innate immune response
Bacterial morphological plasticity (3,629 words) [view diff] exact match in snippet view article find links to article
response to host innate immune response (more exactly in response to Toll-like receptor 4-TLR4). TLR-4 is stimulated by the lipopolysaccharide (LPS) and recruits
Amphotericin B (3,979 words) [view diff] exact match in snippet view article find links to article
antifungal drug amphotericin B promotes inflammatory cytokine release by a Toll-like receptor- and CD14-dependent mechanism". The Journal of Biological Chemistry
NLRP1 (2,215 words) [view diff] exact match in snippet view article find links to article
Keestra AM, van Putten JP (March 2011). "Cleavage and activation of a Toll-like receptor by microbial proteases". Proceedings of the National Academy of Sciences
Alison Rich (academic) (531 words) [view diff] exact match in snippet view article
VP, Seymour GJ, Rich AM. Forkhead box-P3+ regulatory T cells and toll-like receptor 2 co-expression in oral squamous cell carcinoma. Acta Histochemica
Tomáš Cihlář (1,342 words) [view diff] exact match in snippet view article find links to article
capsids. Recently, these entail low molecular weight agonists of TLR7 (toll-like receptor 7). TLR7 receptors recognize single-stranded RNA in endosomes and
Cutibacterium acnes (3,840 words) [view diff] exact match in snippet view article find links to article
"Review of the innate immune response in acne vulgaris: activation of Toll-like receptor 2 in acne triggers inflammatory cytokine responses". Dermatology.
Mesenchymal stem cell (4,861 words) [view diff] no match in snippet view article find links to article
Escherichia coli is mediated by secretion of beta- defensin- 2 via toll- like receptor 4 signalling". Cellular Microbiology. 18 (3): 424–36. doi:10.1111/cmi
MS100a7a15 (914 words) [view diff] exact match in snippet view article find links to article
antimicrobial protein of the skin: regulation by E. coli through Toll-like receptor 4". The Journal of Investigative Dermatology. 127 (11): 2596–604.
DHX36 (1,267 words) [view diff] exact match in snippet view article find links to article
A, Hesselberth JR, Fields S (March 2006). "Binding specificity of Toll-like receptor cytoplasmic domains". European Journal of Immunology. 36 (3): 742–53
Alkaline phosphatase (5,766 words) [view diff] exact match in snippet view article find links to article
well as in suppressing inflammation via repression of the downstream Toll-like receptor (TLR)-4-dependent and MyD88-dependent inflammatory cascade. It dephosphorylates
FLOT2 (1,370 words) [view diff] exact match in snippet view article find links to article
positive regulation of establishment of T cell polarity regulation of toll-like receptor 3 signaling pathway regulation of heterotypic cell-cell adhesion protein
Jawahar L. Mehta (1,198 words) [view diff] exact match in snippet view article find links to article
Ding Z, Liu S, ....Mehta JL. Lectin-like ox-LDL receptor-1 (LOX-1) - toll-like receptor 4 (TLR4) interaction and autophagy in CATH.a differentiated cells
Cord factor (3,844 words) [view diff] exact match in snippet view article find links to article
pro-inflammatory cytokines as well. However, there is also evidence that toll-like receptor 2 (TLR2) in conjunction with the protein MyD-88 is responsible for
FCRL3 (1,914 words) [view diff] exact match in snippet view article find links to article
production positive regulation of B cell proliferation regulation of toll-like receptor 9 signaling pathway positive regulation of MAPK cascade regulation
Tight junction protein 1 (2,033 words) [view diff] exact match in snippet view article find links to article
35179. PMID 10575001. Cario E, Gerken G, Podolsky DK (July 2004). "Toll-like receptor 2 enhances ZO-1-associated intestinal epithelial barrier integrity
Capnocytophaga canimorsus (2,869 words) [view diff] exact match in snippet view article find links to article
IL-8, IL-6 and IL-1α, interferon-γ, and nitric oxide. In addition, toll-like receptor 4 (TLR4 ) normally recognizes pathogens and begins a signalling cascade
Halothane (2,748 words) [view diff] exact match in snippet view article find links to article
anesthetics isoflurane and sevoflurane directly target and attenuate Toll-like receptor 4 system". FASEB Journal. 33 (12): 14528–14541. doi:10.1096/fj.201901570R
BPIFB1 (1,221 words) [view diff] exact match in snippet view article find links to article
response in mucosa innate immune response negative regulation of toll-like receptor 4 signaling pathway immune system process antimicrobial humoral response
Paola Ricciardi-Castagnoli (1,081 words) [view diff] exact match in snippet view article find links to article
Beutler, B (2000). "Physical contact between lipopolysaccharide and Toll-like receptor 4 revealed by genetic complementation". Proceedings of the National
Subunit vaccine (6,745 words) [view diff] exact match in snippet view article find links to article
Vi capsular antigen of Salmonella enterica serotype Typhi reduces Toll-like receptor-dependent interleukin-8 expression in the intestinal mucosa". Infection
Phosphoinositide-dependent kinase-1 (2,109 words) [view diff] exact match in snippet view article find links to article
apoptotic process focal adhesion assembly negative regulation of toll-like receptor signaling pathway peptidyl-serine phosphorylation regulation of endothelial
S100A7A (1,598 words) [view diff] exact match in snippet view article find links to article
antimicrobial protein of the skin: regulation by E. coli through Toll-like receptor 4". J. Invest. Dermatol. 127 (11): 2596–604. doi:10.1038/sj.jid.5700946
Ulf Landmesser (1,264 words) [view diff] case mismatch in snippet view article find links to article
High-Density Lipoprotein Induces Endothelial Dysfunction via Activation of Toll-like Receptor-2." Immunity 38, no. 4 (18 April 2013): 754–68. doi:10.1016/j.immuni
Small interfering RNA (6,732 words) [view diff] exact match in snippet view article find links to article
gene I (RIG-I) may also be involved. The induction of cytokines via toll-like receptor 7 (TLR7) has also been described. Chemical modification of siRNA is
Innate Immunotherapeutics (1,965 words) [view diff] exact match in snippet view article find links to article
T-cell-mediated autoimmune responses in EAE by simultaneously activating innate Toll-like receptor 9 and nucleotide-binding oligomerization domain-containing protein
Nickel allergy (3,598 words) [view diff] exact match in snippet view article find links to article
Th17, Th22, Th1/IFN and the innate immune responses consistent with toll-like receptor 4. Nickel has a wide utility of application in manufactured metals
TAB1 (2,250 words) [view diff] exact match in snippet view article find links to article
signaling pathway in utero embryonic development MyD88-dependent toll-like receptor signaling pathway coronary vasculature development Fc-epsilon receptor
Fc receptor (4,728 words) [view diff] case mismatch in snippet view article find links to article
"FcγRIIIa-Syk Co-signal Modulates CD4+ T-cell Response and Up-regulates Toll-like Receptor (TLR) Expression". J. Biol. Chem. 291 (3): 1368–86. doi:10.1074/jbc
Epizootic hemorrhagic disease (1,941 words) [view diff] case mismatch in snippet view article find links to article
Novakofski JE, et al. (February 2023). "The Impact of Variation in the Toll-like Receptor 3 Gene on Epizootic Hemorrhagic Disease in Illinois Wild White-Tailed
Antonio Lanzavecchia (1,709 words) [view diff] exact match in snippet view article find links to article
A.; Bertoni, F.; Sallusto, F.; Lanzavecchia, A. (2005). "Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1 -polarizing
Cathelicidin antimicrobial peptide (3,677 words) [view diff] exact match in snippet view article find links to article
Stenger S, Li H, Wenzel L, Tan BH, Krutzik SR, et al. (March 2006). "Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response".
ABO blood group system (5,847 words) [view diff] exact match in snippet view article find links to article
2007). "Translational mini-review series on Toll-like receptors: Toll-like receptor ligands as novel pharmaceuticals for allergic disorders". Clinical
Reticulon 4 (1,924 words) [view diff] exact match in snippet view article find links to article
membrane organization blastocyst formation positive regulation of toll-like receptor 9 signaling pathway protein localization to lysosome cellular sphingolipid
ABO (gene) (2,172 words) [view diff] exact match in snippet view article
2007). "Translational mini-review series on Toll-like receptors: Toll-like receptor ligands as novel pharmaceuticals for allergic disorders". Clinical
Apolipoprotein B (4,677 words) [view diff] exact match in snippet view article find links to article
cholesterol efflux post-embryonic development lipoprotein transport toll-like receptor signaling pathway response to estradiol membrane organization chylomicron
Detlef Schuppan (1,365 words) [view diff] exact match in snippet view article find links to article
trypsin inhibitors drive intestinal inflammation via activation of toll-like receptor 4". The Journal of Experimental Medicine. 209 (13): 2395–2408. doi:10
Igor P. Kaidashev (1,336 words) [view diff] exact match in snippet view article find links to article
109-114 Kutsenko NL, Izmailova OV, Vesnina LE, Kaidashev IP. Role of toll-like receptor 2 and 4 gene polymorphisms in the development of allergic diseases
Erythrina alkaloids (1,283 words) [view diff] case mismatch in snippet view article find links to article
Kanki; Hayashi, Masahiko (2013). "Inhibitory Effect of Erythraline on Toll-Like Receptor Signaling Pathway in RAW264.7 Cells". Biological and Pharmaceutical
Gabriella Campadelli-Fiume (1,624 words) [view diff] case mismatch in snippet view article find links to article
PMID 3561254. Herpes Simplex Virus Glycoproteins gH/gL and gB Bind Toll-Like Receptor 2, and Soluble gH/gL Is Sufficient To Activate NF-κB Singh GN, Gupta
Jennifer Stow (1,614 words) [view diff] case mismatch in snippet view article find links to article
Stow, J.L. (2016). "Distinct Roles for APPL1 and APPL2 in Regulating Toll-like Receptor 4 Signaling in Macrophages: APPL Regulation of TLR4 Signaling". Traffic
University of Texas Southwestern Medical Center (4,569 words) [view diff] exact match in snippet view article find links to article
Nobel Prize in Physiology or Medicine for his discovery that the Toll-like receptor 4 (TLR4) is the membrane-spanning component of the mammalian lipopolysaccharide
Systems immunology (3,351 words) [view diff] exact match in snippet view article find links to article
; 16 April 2019 (2019). "Cooperation between T cell receptor and Toll-like receptor 5 signaling for CD4+ T cell activation" (PDF). Science Signaling.
Curcumin synthase (1,624 words) [view diff] exact match in snippet view article find links to article
2002. PMC 118079. PMID 12097249. Zhang G, Ghosh S (January 2001). "Toll-like receptor-mediated NF-kappaB activation: a phylogenetically conserved paradigm
Lactoferrin (5,707 words) [view diff] exact match in snippet view article find links to article
regulation of I-kappaB kinase/NF-kappaB signaling positive regulation of toll-like receptor 4 signaling pathway siderophore-dependent iron import into cell antimicrobial
P110δ (2,559 words) [view diff] no match in snippet view article find links to article
species in neutrophils. p110δ controls lipopolysaccharide induced Toll-like-receptor-4 mediated innate immune responses in dendritic cells and mice carrying
Özlem Türeci (3,474 words) [view diff] exact match in snippet view article find links to article
Kerstin C Walzer; et al. (19 April 2019). "Intravenous delivery of the toll-like receptor 7 agonist SC1 confers tumor control by inducing a CD8+ T cell response"
Metatranscriptomics (4,185 words) [view diff] exact match in snippet view article find links to article
1038/nri3430. PMID 23618829. S2CID 205491968. Abreu MT (February 2010). "Toll-like receptor signalling in the intestinal epithelium: how bacterial recognition
Biodiversity and drugs (2,072 words) [view diff] exact match in snippet view article find links to article
Hadaś, Edward (2019). "The modulatory effect of Artemisia annua L. on toll-like receptor expression in Acanthamoeba infected mouse lungs". Experimental Parasitology
PRDM1 (2,688 words) [view diff] exact match in snippet view article find links to article
DNA (abundant in bacterial genomes), and cancer inflammation via Toll-like receptor (TLR) 3, TLR-4, TLR-9, and STAT signaling, respectively. The increased
PRKCE (6,268 words) [view diff] exact match in snippet view article find links to article
positive regulation of synaptic transmission, GABAergic TRAM-dependent toll-like receptor 4 signaling pathway locomotory exploration behavior platelet activation
Antimicrobial peptides (6,542 words) [view diff] no match in snippet view article find links to article
is an immunomodulator that acts through p62, a protein involved in toll like receptor based signalling of infection. The peptide is being examined in a
Surfactant protein A2 (3,586 words) [view diff] exact match in snippet view article find links to article
Biological process respiratory gaseous exchange by respiratory system toll-like receptor signaling pathway surfactant homeostasis positive regulation of phagocytosis
GroEL (5,438 words) [view diff] exact match in snippet view article find links to article
maturation positive regulation of macrophage activation MyD88-dependent toll-like receptor signaling pathway isotype switching to IgG isotypes B cell activation
Yellow fever (12,177 words) [view diff] exact match in snippet view article find links to article
"Sensing of viral infection and activation of innate immunity by toll-like receptor 3". Clinical Microbiology Reviews. 21 (1): 13–25. doi:10.1128/CMR
Leishmania (6,163 words) [view diff] exact match in snippet view article find links to article
over the outside of the cell. Lipophosphoglycan is a trigger for toll-like receptor 2, a signalling receptor involved in triggering an innate immune response
Nicotinamide phosphoribosyltransferase (3,216 words) [view diff] case mismatch in snippet view article find links to article
CL, Danilov SM, Zhou T, Chiang ET, et al. (August 2015). "Unique Toll-Like Receptor 4 Activation by NAMPT/PBEF Induces NFκB Signaling and Inflammatory
Coeliac disease (15,819 words) [view diff] exact match in snippet view article find links to article
disease, a subset of autoantibodies against transglutaminase binds toll-like receptor 4 and induces activation of monocytes". PLOS Med. 3 (9): e358. doi:10
Surfactant protein A1 (3,387 words) [view diff] exact match in snippet view article find links to article
respiratory gaseous exchange by respiratory system lipid transport toll-like receptor signaling pathway opsonization surfactant homeostasis positive regulation
Vein graft failure (2,577 words) [view diff] exact match in snippet view article find links to article
IE; Fischer, JW; Jukema, JW; Niessen, HW; Quax, PH (May 2011). "Toll-like receptor 4 is involved in human and mouse vein graft remodeling, and local
Estrogen receptor alpha (6,329 words) [view diff] exact match in snippet view article find links to article
regulation of inflammatory response response to estradiol regulation of toll-like receptor signaling pathway regulation of transcription by RNA polymerase II
Morphine (13,611 words) [view diff] exact match in snippet view article find links to article
pathway. Usually, the p38 within the dendritic cell expresses TLR 4 (toll-like receptor 4), which is activated through the ligand LPS (lipopolysaccharide)
Kishor Wasan (1,315 words) [view diff] case mismatch in snippet view article find links to article
Carlos G.; et al. (August 1, 2008). "Discovery and Development of Toll-Like Receptor 4 (TLR4) Antagonists: A New Paradigm for Treating Sepsis and Other
Jeffrey Flier (3,578 words) [view diff] exact match in snippet view article find links to article
inflammatory phenomena in metabolic disease, Flier helped establish that Toll-like receptor 4 (TLR4) activation in adipocytes and macrophages mediates inflammation
Human endogenous retrovirus-W (4,782 words) [view diff] exact match in snippet view article find links to article
envelope protein is a potent, endogenous and pathogenic agonist of human toll-like receptor 4: Relevance of GNbAC1 in multiple sclerosis treatment". Journal of
S. Murty Srinivasula (1,517 words) [view diff] exact match in snippet view article find links to article
Srinivasa M. (25 January 2011). "Nrf2-mediated induction of p62 controls Toll-like receptor-4-driven aggresome-like induced structure formation and autophagic
DSCAM (3,787 words) [view diff] exact match in snippet view article find links to article
0127.x. PMID 15199960. S2CID 6188654. Akira, S; Takeda K (2004). "Toll-like receptor signalling". Nat Rev Immunol. 4 (7): 499–511. doi:10.1038/nri1391
High Affinity K+ transporter HAK5 (2,305 words) [view diff] exact match in snippet view article find links to article
which signals a downstream immune response. In animal cells the toll-like receptor TLR4 binds the bacterial PAMP LPS (lipopolysaccharide) and induces
Influenza vaccine (17,526 words) [view diff] case mismatch in snippet view article find links to article
Massari P (April 2014). "Immune Adjuvant Effect of Molecularly-defined Toll-Like Receptor Ligands". Vaccines. 2 (2): 323–53. doi:10.3390/vaccines2020323. PMC 4494261
Julie McElrath (4,171 words) [view diff] case mismatch in snippet view article find links to article
Mullins, James I; McElrath, M. Juliana; Lingappa, Jairam R (2014). "Toll-like Receptor Polymorphism Associations with HIV-1 Outcomes Among Sub-Saharan Africans"
Cytochrome b-245, alpha polypeptide (4,832 words) [view diff] exact match in snippet view article find links to article
stimulus hydrogen peroxide biosynthetic process positive regulation of toll-like receptor 2 signaling pathway positive regulation of superoxide anion generation
Tuberculosis management (21,386 words) [view diff] exact match in snippet view article find links to article
Stenger S, Li H, Wenzel L, Tan BH, Krutzik SR, et al. (March 2006). "Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response".
2012 in science (38,831 words) [view diff] case mismatch in snippet view article find links to article
2022-01-17. Hutchinson, M. R.; et al. (2012-08-15). "Opioid Activation of Toll-Like Receptor 4 Contributes to Drug Reinforcement". Journal of Neuroscience. Society
Peptidoglycan recognition protein (11,844 words) [view diff] exact match in snippet view article find links to article
protein 6 (zfPGRP6) mediated differentially expressed genes involved in Toll-like receptor signaling pathway and caused increased susceptibility to Flavobacterium
Epigenetics of autoimmune disorders (5,725 words) [view diff] exact match in snippet view article find links to article
in regulating the immune system by providing negative feedback to toll-like receptor (TLR) signaling which is used to engage the innate immune response