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Longer titles found: Toll-like receptor 1 (view), Toll-like receptor 10 (view), Toll-like receptor 11 (view), Toll-like receptor 2 (view), Toll-like receptor 3 (view), Toll-like receptor 4 (view), Toll-like receptor 5 (view), Toll-like receptor 6 (view), Toll-like receptor 7 (view), Toll-like receptor 8 (view), Toll-like receptor 9 (view)

searching for Toll-like receptor 303 found (494 total)

alternate case: toll-like receptor

Poly ICLC (122 words) [view diff] no match in snippet view article find links to article

polylysine. It is under trial for use in cancer. Poly I:C is a ligand for toll like receptor-3, which usually triggers on the structurally similar double-stranded

TICAM2 (497 words) [view diff] exact match in snippet view article find links to article

Information, U.S. National Library of Medicine. "Entrez Gene: TICAM2 toll-like receptor adaptor molecule 2". Sullivan C, Postlethwait JH, Lage CR, et al.

IRAK2 (704 words) [view diff] exact match in snippet view article find links to article

O'Neill LA (Sep 2001). "Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction". Nature. 413 (6851): 78–83. Bibcode:2001Natur

Polyinosinic:polycytidylic acid (396 words) [view diff] exact match in snippet view article find links to article

to simulate viral infections. Poly I:C is known to interact with toll-like receptor 3 (TLR3), which is expressed at the endosomal membrane of B-cells

Resiquimod (569 words) [view diff] exact match in snippet view article find links to article

macrophages. It has several mechanisms of action, being both an agonist for toll-like receptor 7 and 8, and an upregulator of the opioid growth factor receptor.

CpG oligodeoxynucleotide (1,393 words) [view diff] case mismatch in snippet view article find links to article

CpG PAMP is recognized by the pattern recognition receptor (PRR) Toll-Like Receptor 9 (TLR9), which is constitutively expressed only in B cells and plasmacytoid

Entolimod (1,044 words) [view diff] exact match in snippet view article find links to article

treatment. Entolimod is a recombinant protein that acts as an agonist of toll-like receptor 5 (TLR5), an innate immunity receptor. Entolimod activation of TLR5

UNC93B1 (538 words) [view diff] exact match in snippet view article find links to article

cytoplasmic vesicle Biological process toll-like receptor 9 signaling pathway intracellular protein transport toll-like receptor 3 signaling pathway adaptive immune

Pokeweed mitogen (636 words) [view diff] exact match in snippet view article find links to article

proliferation of B cells, plasma cells and T cells. This lectin contains Toll-like receptor 4 (TLR4) proteins which signals for the B-cell for a proliferative

LILRA4 (548 words) [view diff] exact match in snippet view article find links to article

"Plasmacytoid dendritic cell–specific receptor ILT7–FcɛRIγ inhibits Toll-like receptor–induced interferon production". J. Exp. Med. 203 (6): 1399–405. doi:10

Lipid A (1,384 words) [view diff] exact match in snippet view article find links to article

processes. Lipid A (and LPS) has been demonstrated to activate cells via Toll-like receptor 4 (TLR4), MD-2 and CD14 on the cell surface. Consequently, lipid A

MARCKS (1,376 words) [view diff] exact match in snippet view article find links to article

trafficking and mitogenesis. MARCKS has been shown to regulate the Toll-like receptor pathway in macrophages MARCKS has been shown to interact with TOB1

PIK3AP1 (421 words) [view diff] exact match in snippet view article find links to article

signaling toll-like receptor 9 signaling pathway toll-like receptor 2 signaling pathway toll-like receptor 4 signaling pathway toll-like receptor 7 signaling

PIK3AP1 (421 words) [view diff] exact match in snippet view article find links to article

signaling toll-like receptor 9 signaling pathway toll-like receptor 2 signaling pathway toll-like receptor 4 signaling pathway toll-like receptor 7 signaling

RAB7B (411 words) [view diff] exact match in snippet view article find links to article

selectively expressed in monocytic cells. By promoting the degradation of toll-like receptor 4, RAB7B can negatively regulate the inflammatory activation of macrophages

Ubiquitin A-52 residue ribosomal protein fusion product 1 (825 words) [view diff] exact match in snippet view article find links to article

pathway regulation of type I interferon production TRIF-dependent toll-like receptor signaling pathway Fc-epsilon receptor signaling pathway endosomal

Akiko Iwasaki (1,760 words) [view diff] exact match in snippet view article find links to article

infections. According to Google Scholar, one of her publications, "Toll-like receptor control of the adaptive immune response," has been cited over 5,300

HspE7 (1,008 words) [view diff] exact match in snippet view article find links to article

already infected with HPV. The candidate is being developed with a Toll-like receptor 3 (TLR3) agonist adjuvant for multiple indications, including cervical

IRF7 (1,417 words) [view diff] exact match in snippet view article find links to article

MyD88-independent toll-like receptor signaling pathway positive regulation of type I interferon production innate immune response regulation of MyD88-dependent toll-like

Protease-activated receptor 2 (2,715 words) [view diff] exact match in snippet view article find links to article

regulation of toll-like receptor 4 signaling pathway positive regulation of I-kappaB kinase/NF-kappaB signaling positive regulation of toll-like receptor 2 signaling

40S ribosomal protein S27a (929 words) [view diff] exact match in snippet view article find links to article

pathway regulation of type I interferon production TRIF-dependent toll-like receptor signaling pathway Fc-epsilon receptor signaling pathway endosomal

PELI1 (510 words) [view diff] exact match in snippet view article find links to article

SH (Sep 2006). "Smad6 negatively regulates interleukin 1-receptor-Toll-like receptor signaling through direct interaction with the adaptor Pellino-1".

(+)-Morphine (302 words) [view diff] exact match in snippet view article

derives its antianalgesic effects by being a selective-agonist of the Toll-like receptor 4 (TLR4), which due to not binding to opioid receptors allows it to

Baculoviral IAP repeat-containing protein 3 (1,388 words) [view diff] exact match in snippet view article find links to article

heterooligomerization MyD88-independent toll-like receptor signaling pathway TRIF-dependent toll-like receptor signaling pathway negative regulation of

TNIP2 (783 words) [view diff] exact match in snippet view article find links to article

polymerase II apoptotic process toll-like receptor 9 signaling pathway toll-like receptor 2 signaling pathway toll-like receptor 3 signaling pathway protein

List of human clusters of differentiation (492 words) [view diff] exact match in snippet view article find links to article

Toll-like receptor 8 (TLR8); Genetic variants in TLR8 have recently been linked to susceptibility to pulmonary tuberculosis. CD289 Toll-like receptor

TNFAIP3 (1,971 words) [view diff] exact match in snippet view article find links to article

ubiquitin-dependent protein catabolic process negative regulation of toll-like receptor 2 signaling pathway negative regulation of nucleotide-binding oligomerization

S100A9 (2,090 words) [view diff] exact match in snippet view article find links to article

together, MRP8 and MRP14 regulate myeloid cell function by binding to Toll-like receptor 4 (TLR4) and the receptor for advanced glycation end products. Intracellular

Bartonella quintana (1,482 words) [view diff] exact match in snippet view article find links to article

is its lipopolysaccharide covering which is an antagonist of the toll-like receptor 4. The reason this infection might persist is because this organism

Caspase 8 (2,278 words) [view diff] exact match in snippet view article find links to article

(NF-κB) after stimulation through antigen receptors, Fc receptors, or Toll-like receptor 4 in T, B, and natural killer cells. Biochemically, caspase-8 was

UBE2D2 (1,291 words) [view diff] exact match in snippet view article find links to article

stimulatory C-type lectin receptor signaling pathway TRIF-dependent toll-like receptor signaling pathway Fc-epsilon receptor signaling pathway protein K48-linked

UBE2D1 (1,507 words) [view diff] exact match in snippet view article find links to article

cycle phase transition MyD88-independent toll-like receptor signaling pathway TRIF-dependent toll-like receptor signaling pathway Sources:Amigo / QuickGO

UBE2D3 (1,253 words) [view diff] exact match in snippet view article find links to article

damage stimulus protein K11-linked ubiquitination TRIF-dependent toll-like receptor signaling pathway protein K48-linked ubiquitination regulation of

Baculoviral IAP repeat-containing protein 2 (1,883 words) [view diff] exact match in snippet view article find links to article

acid-templated transcription MyD88-independent toll-like receptor signaling pathway TRIF-dependent toll-like receptor signaling pathway positive regulation of

Depyrogenation (1,759 words) [view diff] case mismatch in snippet view article find links to article

monocytes). This monomerises the aggregated LPS, as the LPS receptor Toll-like Receptor 4 (TLR4) cannot recognise LPS while aggregated. Monomeric LPS is then

Black guineafowl (850 words) [view diff] exact match in snippet view article find links to article

currently known to researchers. The black guineafowl's genome includes a toll-like receptor (TLR1) which plays an important role in the bird's immune system.

IKK2 (1,527 words) [view diff] exact match in snippet view article find links to article

signaling pathway T cell receptor signaling pathway TRIF-dependent toll-like receptor signaling pathway Fc-epsilon receptor signaling pathway positive regulation

TNIP3 (gene) (576 words) [view diff] exact match in snippet view article

"Expression of the NF-kappaB inhibitor ABIN-3 in response to TNF and toll-like receptor 4 stimulation is itself regulated by NF-kappaB". J. Cell. Mol. Med

Mariano Barbacid (641 words) [view diff] case mismatch in snippet view article find links to article

mammalian cyclin-dependent kinases and their inhibitors." (2000). "Toll-like Receptor-4 (TLR4) Down-regulates MicroRNA-107, Increasing Macrophage Adhesion

IRAK3 (708 words) [view diff] exact match in snippet view article find links to article

to exogenous dsRNA protein phosphorylation negative regulation of toll-like receptor signaling pathway cytokine-mediated signaling pathway response to

IKBKG (3,277 words) [view diff] exact match in snippet view article find links to article

polyubiquitination of IRAK-1 is required for interleukin-1 receptor- and toll-like receptor-mediated NF-kappaB activation". Molecular and Cellular Biology. 28

MAP3K7 (1,717 words) [view diff] exact match in snippet view article find links to article

NF-kappaB-inducing kinase activity I-kappaB phosphorylation MyD88-dependent toll-like receptor signaling pathway transcription, DNA-templated Fc-epsilon receptor

Glucuronic acid (1,882 words) [view diff] exact match in snippet view article find links to article

glucuronidated metabolite of ethanol, ethyl glucuronide (ETG), act on toll-like receptor 4 to aggravate both acute and chronic inflammatory conditions as well

Gunther Hartmann (1,536 words) [view diff] exact match in snippet view article find links to article

he characterized the CpG motif in DNA that is detected by human Toll-like receptor 9 (TLR9) and then back in Munich he studied the immunobiological consequences

FUT7 (1,001 words) [view diff] exact match in snippet view article find links to article

A, Hesselberth JR, Fields S (March 2006). "Binding specificity of Toll-like receptor cytoplasmic domains". European Journal of Immunology. 36 (3): 742–53

Ubiquitin B (996 words) [view diff] exact match in snippet view article find links to article

positive regulation of protein monoubiquitination TRIF-dependent toll-like receptor signaling pathway Fc-epsilon receptor signaling pathway endosomal

Cathepsin K (1,713 words) [view diff] exact match in snippet view article find links to article

K, Kato S, Saftig P, Takayanagi H,. (2008). Cathepsin K-dependent toll-like receptor 9 signaling revealed in experimental arthritis. Science, 319(5863)

IRF1 (1,827 words) [view diff] exact match in snippet view article find links to article

IFN-gamma-induced IFN regulatory factor 1 transcription factor by MyD88 in Toll-like receptor-dependent gene induction program". Proc. Natl. Acad. Sci. U.S.A. 103

MAP3K7IP3 (604 words) [view diff] exact match in snippet view article find links to article

stimulatory C-type lectin receptor signaling pathway MyD88-dependent toll-like receptor signaling pathway Fc-epsilon receptor signaling pathway JNK cascade

CD300LF (764 words) [view diff] exact match in snippet view article find links to article

negative regulation of MyD88-dependent toll-like receptor signaling pathway TRIF-dependent toll-like receptor signaling pathway interleukin-13-mediated

Zymosan (191 words) [view diff] exact match in snippet view article find links to article

action. Sato M, Sano H, Iwaki D, et al. (2003). "Direct binding of Toll-like receptor 2 to zymosan, and zymosan-induced NF-kappa B activation and TNF-alpha

Nicotinamide (2,425 words) [view diff] exact match in snippet view article find links to article

has been shown to prevent Cutibacterium acnes-induced activation of toll-like receptor 2, which ultimately results in the down-regulation of pro-inflammatory

Nucleoside-modified messenger RNA (2,503 words) [view diff] exact match in snippet view article find links to article

barriers against foreign mRNA, such as innate immune system receptors, toll-like receptor (TLR) 7 and TLR8, located in endosomal membranes. RNA sensors like

Dirt (939 words) [view diff] exact match in snippet view article find links to article

LV; Schmidt, RR (22 November 2009), "Commensal bacteria regulate Toll-like receptor 3–dependent inflammation after skin injury", Nature Medicine, 15 (12):

Farnesoid X receptor (1,945 words) [view diff] exact match in snippet view article find links to article

glucose stimulus positive regulation of ammonia assimilation cycle toll-like receptor 4 signaling pathway immune system process histone H3-R17 methylation

TANK-binding kinase 1 (2,305 words) [view diff] exact match in snippet view article find links to article

transcription factors, NF-kappa B and IFN-regulatory factor-3, in the Toll-like receptor signaling". Journal of Immunology. 171 (8): 4304–4310. doi:10.4049/jimmunol

Burghardt Wittig (2,139 words) [view diff] exact match in snippet view article find links to article

Scheithauer, W; Schmoll, HJ (2015). "MGN1703, an immunomodulator and toll-like receptor 9 (TLR-9) agonist: From bench to bedside". Crit Rev Oncol Haematol

Plasmacytoid dendritic cell (1,833 words) [view diff] exact match in snippet view article find links to article

HLA-DR, CD123, blood-derived dendritic cell antigen-2 (BDCA-2), Toll-like receptor (TLR) 7 and TLR9 within endosomal compartments. Expression of TLR

RIPK2 (965 words) [view diff] exact match in snippet view article find links to article

regulation of transcription by RNA polymerase II toll-like receptor 4 signaling pathway toll-like receptor 2 signaling pathway innate immune response MAPK

IRF8 (2,321 words) [view diff] exact match in snippet view article find links to article

sequence-binding protein regulate the myeloid expression of the human Toll-like receptor 4 gene". J. Biol. Chem. 275 (13): 9773–81. doi:10.1074/jbc.275.13

S100A14 (610 words) [view diff] exact match in snippet view article find links to article

antimicrobial protein of the skin: regulation by E. coli through Toll-like receptor 4". The Journal of Investigative Dermatology. 127 (11): 2596–604.

LILRA1 (499 words) [view diff] exact match in snippet view article find links to article

PMID 21388353. Pilsbury LE, Allen RL, Vordermeier M (2010). "Modulation of Toll-like receptor activity by leukocyte Ig-like receptors and their effects during bacterial

Andreas Peschel (737 words) [view diff] exact match in snippet view article find links to article

Macek B, Wolz C, Götz F, Otto M, Kretschmer D, Peschel A. 2016. “Toll-like receptor 2 activation depends on lipopeptide shedding by bacterial surfactants

Receptor modulator (982 words) [view diff] exact match in snippet view article find links to article

effect. Some common examples are opium derivates, such as heroin and Toll-like receptor agonists. Heroin functions in this manner, along with other opioids

Septic shock (3,599 words) [view diff] exact match in snippet view article find links to article

as 10 pg/mL) results in intracellular signaling via an associated "Toll-like receptor" protein 4 (TLR-4). This signaling results in the activation of nuclear

S100A8 (1,048 words) [view diff] exact match in snippet view article find links to article

Gene ontology Molecular function Toll-like receptor 4 binding RAGE receptor binding microtubule binding protein binding calcium ion binding arachidonic

FLOT1 (1,178 words) [view diff] exact match in snippet view article find links to article

regulation of toll-like receptor 4 signaling pathway positive regulation of heterotypic cell-cell adhesion positive regulation of toll-like receptor 3 signaling

White-winged flufftail (1,239 words) [view diff] exact match in snippet view article find links to article

Antoinette Kotze (November 9, 2016). "Lack of diversity at innate immunity Toll-like receptor genes in the Critically Endangered White-winged Flufftail (Sarothrura

Bruton's tyrosine kinase (2,837 words) [view diff] case mismatch in snippet view article find links to article

Bruijn MJ, Appelman MK, Pal Singh S, Hendriks RW, Corneth OB (2019). "Toll-Like Receptor Signaling Drives Btk-Mediated Autoimmune Disease". Frontiers in Immunology

CD300A (574 words) [view diff] exact match in snippet view article find links to article

proliferation signal transduction negative regulation of MyD88-dependent toll-like receptor signaling pathway neutrophil degranulation Sources:Amigo / QuickGO

Ubiquitin C (4,261 words) [view diff] exact match in snippet view article find links to article

polyubiquitination of IRAK-1 is required for interleukin-1 receptor- and toll-like receptor-mediated NF-kappaB activation". Molecular and Cellular Biology. 28

FAM114A1 (721 words) [view diff] exact match in snippet view article find links to article

chromosome: TLR1: Toll-like receptor (TLR) 1 plays a role in pathogen recognition and activation of innate immunity. TLR6: Toll-like receptor (TLR) 6 plays

PIK3R4 (565 words) [view diff] exact match in snippet view article find links to article

transduction pathways mediated by the interaction of CpG DNA with Toll-like receptor 9". Semin. Immunol. 16 (1): 17–22. doi:10.1016/j.smim.2003.10.009

Katalin Karikó (5,090 words) [view diff] exact match in snippet view article find links to article

Karikó; Drew Weissman; Frank A Welsh (1 November 2004). "Inhibition of toll-like receptor and cytokine signaling--a unifying theme in ischemic tolerance". Journal

TRAF1 (2,025 words) [view diff] exact match in snippet view article find links to article

Watts TH (2017). "The signaling adaptor TRAF1 negatively regulates Toll-like receptor signaling and this underlies its role in rheumatic disease". Nature

DAB2IP (861 words) [view diff] exact match in snippet view article find links to article

regulatory subunit binding phosphatidylinositol-4-phosphate binding Toll-like receptor 4 binding kinase binding protein phosphatase 2A binding mitogen-activated

Cefodizime (625 words) [view diff] exact match in snippet view article find links to article

was shown in a 2004 study that cefodizime increased expression of toll-like receptor 4 (TLR-4) in neutrophils stimulated by Klebsiella pneumoniae infection

CD180 (790 words) [view diff] exact match in snippet view article find links to article

cell proliferation involved in immune response immune system process toll-like receptor signaling pathway inflammatory response Sources:Amigo / QuickGO

HAVCR2 (2,940 words) [view diff] exact match in snippet view article find links to article

presenting cell negative regulation of tumor necrosis factor production toll-like receptor 9 signaling pathway negative regulation of type I interferon production

MBL deficiency (890 words) [view diff] exact match in snippet view article find links to article

Zhengliang (March 7, 2011). "Mannan-binding lectin directly interacts with Toll-like receptor 4 and suppresses lipopolysaccharide-induced inflammatory cytokine

CD86 (3,221 words) [view diff] exact match in snippet view article find links to article

cytokine stimulus T cell proliferation involved in immune response toll-like receptor signaling pathway positive regulation of transcription, DNA-templated

CHUK (2,765 words) [view diff] exact match in snippet view article find links to article

response to hydroperoxide response to organic substance TRIF-dependent toll-like receptor signaling pathway Fc-epsilon receptor signaling pathway protein phosphorylation

TRAP1 (787 words) [view diff] exact match in snippet view article find links to article

Brown V, Brown RA, Ozinsky A, et al. (2006). "Binding specificity of Toll-like receptor cytoplasmic domains". Eur. J. Immunol. 36 (3): 742–53. doi:10.1002/eji

NLRP6 (333 words) [view diff] exact match in snippet view article find links to article

of immune response regulation of autophagy negative regulation of toll-like receptor signaling pathway negative regulation of inflammatory response to

LILRA2 (697 words) [view diff] exact match in snippet view article find links to article

interleukin-6 production interleukin-8 production negative regulation of toll-like receptor 4 signaling pathway granulocyte colony-stimulating factor production

TRAF3 (2,200 words) [view diff] exact match in snippet view article find links to article

process Toll signaling pathway immune system process TRIF-dependent toll-like receptor signaling pathway protein ubiquitination negative regulation of NF-kappaB

Granule (cell biology) (1,737 words) [view diff] exact match in snippet view article

hexosaminidase. An electron-dense granule defined by the presence of Toll-like receptor 9 (TLR9) and protein disulfide isomerase (PDI), termed the T granule

FAM185A (788 words) [view diff] exact match in snippet view article find links to article

FAM185a expression is greatly decreased in ROR1-alpha knockout mice and toll-like receptor 5 knockout mice. Mice also show a decrease in FAM185a expression in

Viperin (1,413 words) [view diff] exact match in snippet view article find links to article

activation immune system process response to virus positive regulation of toll-like receptor 7 signaling pathway negative regulation of viral genome replication

FADD (4,191 words) [view diff] exact match in snippet view article find links to article

SM, Pope RM (2004). "Fas ligation on macrophages enhances IL-1R1-Toll-like receptor 4 signaling and promotes chronic inflammation". Nature Immunology

Spontaneous remission (1,041 words) [view diff] exact match in snippet view article find links to article

has a shiga toxin-like structure and should be combined with other Toll-like receptor ligands in cancer therapy" (PDF). Cancer Immunology, Immunotherapy

Beth Mallard (299 words) [view diff] exact match in snippet view article find links to article

Times. Retrieved 10 July 2014. Mallard, Beth (2011). The role of Toll-like receptor 4 in Concanavalin A-induced immune-mediated hepatitis (Doctoral thesis)

TYRO3 (962 words) [view diff] exact match in snippet view article find links to article

cellular homeostasis protein kinase B signaling negative regulation of toll-like receptor signaling pathway secretion by cell negative regulation of inflammatory

RGC100 (79 words) [view diff] case mismatch in snippet view article find links to article

Rohayem, Jacques (2013). "Activation of Dendritic Cells by the Novel Toll-Like Receptor 3 Agonist RGC100". Clinical and Developmental Immunology. 2013: 283649

Cell–cell recognition (2,051 words) [view diff] no match in snippet view article find links to article

Marta; Zhao, Lue Ping; Kaplan, Gilla; Aderem, Alan (15 January 2008). "Toll‐Like Receptor 2 (TLR2) Polymorphisms Are Associated with Reversal Reaction in Leprosy"

CLEC10A (1,300 words) [view diff] case mismatch in snippet view article find links to article

Specific Marker for Human CD1c+ Dendritic Cells and Enhances Their Toll-Like Receptor 7/8-Induced Cytokine Secretion". Frontiers in Immunology. 9: 744.

Lysophosphatidylserine (323 words) [view diff] exact match in snippet view article find links to article

lipid cross-talk. Schistosomal lyso-phosphatidylserine activates toll-like receptor 2 and affects immune polarization". J Biol Chem. 277 (50): 48122–9

DUSP1 (1,185 words) [view diff] exact match in snippet view article find links to article

enhances nontypeable Haemophilus influenzae-induced expression of toll-like receptor 2". The Journal of Biological Chemistry. 277 (49): 47444–50. doi:10

RG7795 (196 words) [view diff] exact match in snippet view article find links to article

Bhagchandani, Jeremiah A.Johnson, and Darrell J.Irvine (2021). "Evolution of Toll-like receptor 7/8 agonist therapeutics and their delivery approaches: From antiviral

PPAR agonist (1,045 words) [view diff] case mismatch in snippet view article find links to article

"Targeting the Toll of Drug Abuse: The Translational Potential of Toll-Like Receptor 4". CNS & Neurological Disorders Drug Targets. 14 (6): 692–9. doi:10

MAP3K7IP2 (1,677 words) [view diff] exact match in snippet view article find links to article

M, Nie H, Silva AM, Williams BR, Li X (2003). "Poly(I-C)-induced Toll-like receptor 3 (TLR3)-mediated activation of NFkappa B and MAP kinase is through

Fibrinogen alpha chain (1,087 words) [view diff] exact match in snippet view article find links to article

transduction induction of bacterial agglutination platelet activation toll-like receptor signaling pathway post-translational protein modification Sources:Amigo

RPS6KA3 (1,380 words) [view diff] exact match in snippet view article find links to article

transduction positive regulation of transcription by RNA polymerase II toll-like receptor signaling pathway apoptotic process peptidyl-serine phosphorylation

PELI2 (391 words) [view diff] exact match in snippet view article find links to article

Dong W, Chen L, et al. (2004). "BCL10 mediates lipopolysaccharide/toll-like receptor-4 signaling through interaction with Pellino2". J. Biol. Chem. 279

Galectin-9 (2,173 words) [view diff] exact match in snippet view article find links to article

regulation of interferon-gamma production response to interleukin-1 toll-like receptor 4 signaling pathway maternal process involved in female pregnancy

Integrin beta 2 (1,299 words) [view diff] exact match in snippet view article find links to article

process leukocyte cell-cell adhesion endodermal cell differentiation toll-like receptor 4 signaling pathway positive regulation of nitric oxide biosynthetic

Immune complex (1,295 words) [view diff] exact match in snippet view article find links to article

Michelle R.; Gosselin, Edmund J. (November 2019). "Fcγ receptors and toll-like receptor 9 synergize to drive immune complex-induced dendritic cell maturation"

PTPN22 (3,897 words) [view diff] exact match in snippet view article find links to article

regulation of natural killer cell proliferation positive regulation of toll-like receptor 3 signaling pathway regulation of T cell receptor signaling pathway

Immune complex (1,295 words) [view diff] exact match in snippet view article find links to article

Michelle R.; Gosselin, Edmund J. (November 2019). "Fcγ receptors and toll-like receptor 9 synergize to drive immune complex-induced dendritic cell maturation"

Polyporus umbellatus (437 words) [view diff] exact match in snippet view article find links to article

activation and maturation of murine bone-derived dendritic cells via toll-like receptor 4". Cell Immunol. 265 (1): 50–6. doi:10.1016/j.cellimm.2010.07.002

MAPKAPK3 (1,042 words) [view diff] exact match in snippet view article find links to article

peptidyl-serine phosphorylation protein autophosphorylation signal transduction toll-like receptor signaling pathway MAPK cascade intracellular signal transduction Sources:Amigo

IKBKE (1,381 words) [view diff] exact match in snippet view article find links to article

interferon-beta cellular response to DNA damage stimulus TRIF-dependent toll-like receptor signaling pathway protein phosphorylation response to type I interferon

Acute-phase protein (1,096 words) [view diff] exact match in snippet view article find links to article

of CD14 and lipopolysaccharide-binding protein for activation of toll-like receptor (TLR)2 as well as TLR4 Reconstitution of TLR2- and TLR4-activation

PTPRS (1,383 words) [view diff] exact match in snippet view article find links to article

negative regulation of interferon-beta production negative regulation of toll-like receptor 9 signaling pathway negative regulation of neuron projection development

Imiquimod (1,712 words) [view diff] exact match in snippet view article find links to article

synergistically. Imiquimod stimulates the innate immune system by activating toll-like receptor 7 (TLR7), commonly involved in pathogen recognition. Cells activated

PJA2 (502 words) [view diff] exact match in snippet view article find links to article

protein ubiquitination inflammatory response positive regulation of toll-like receptor 2 signaling pathway regulation of macrophage activation innate immune

Melanocyte (2,278 words) [view diff] no match in snippet view article find links to article

response to activation of Pattern Recognition Receptors (PRRs) such as Toll Like Receptor 4 (TLR4) which recognize MAMPs. MAMPs, also known as PAMPs, are microbial

TRAFD1 (515 words) [view diff] exact match in snippet view article find links to article

interferon- and LPS-inducible gene acting as a negative regulator of toll-like receptor signaling". J. Biol. Chem. 280 (50): 41289–97. doi:10.1074/jbc.M508221200

Coxsackie B virus (1,884 words) [view diff] exact match in snippet view article find links to article

arrhythmia. Studies in mice suggest that CB3 enters cells by means of toll-like receptor 4. Both CB3 and CB4 exploit cellular autophagy to promote replication

Antigen (2,435 words) [view diff] exact match in snippet view article find links to article

(December 2006). "Adjuvant-enhanced antibody responses in the absence of toll-like receptor signaling". Science. 314 (5807): 1936–1938. Bibcode:2006Sci...314

Gluten (6,946 words) [view diff] exact match in snippet view article find links to article

fibromyalgia, psychological disturbances, and dermatitis. ATIs may cause toll-like receptor 4 (TLR4)-mediated intestinal inflammation in humans. People can also

IL17RD (1,360 words) [view diff] exact match in snippet view article find links to article

Wurst W, et al. (March 2015). "Orphan receptor IL-17RD regulates Toll-like receptor signalling via SEFIR/TIR interactions". Nature Communications. 6 (1):

AOAH (802 words) [view diff] case mismatch in snippet view article find links to article

non-stimulatory and can be a potent inhibitor of LPS sensing via the MD-2--Toll-like Receptor 4 (TLR4). The enzyme's other known substrates include bacterial lipopeptides

CpG site (5,481 words) [view diff] exact match in snippet view article find links to article

chimpanzees. Unmethylated CpG dinucleotide sites can be detected by Toll-like receptor 9 (TLR 9) on plasmacytoid dendritic cells, monocytes, natural killer

MAP3K2 (1,505 words) [view diff] exact match in snippet view article find links to article

"Identification of MEKK2/3 serine phosphorylation site targeted by the Toll-like receptor and stress pathways". The EMBO Journal. 25 (1): 97–107. doi:10.1038/sj

LYN (3,807 words) [view diff] exact match in snippet view article find links to article

migration ephrin receptor signaling pathway negative regulation of toll-like receptor 2 signaling pathway T cell costimulation response to peptide hormone

Chronic pulmonary aspergillosis (2,907 words) [view diff] exact match in snippet view article find links to article

of developing chronic pulmonary aspergillosis, such as defects to toll-like receptor (TLR) 4, IL1 and IL15, TLR3, TLR10, TREM1, VEGFA, DENND1B, and PLAT

IκBα (1,526 words) [view diff] exact match in snippet view article find links to article

transcription by RNA polymerase II apoptotic process liver regeneration toll-like receptor 4 signaling pathway protein deubiquitination I-kappaB kinase/NF-kappaB

Cathepsin B (1,346 words) [view diff] exact match in snippet view article find links to article

of apoptotic process epithelial cell differentiation proteolysis toll-like receptor signaling pathway decidualization cellular response to thyroid hormone

Kupffer cell (1,861 words) [view diff] exact match in snippet view article find links to article

injury. The cascade begins with endotoxin-mediated activation of the Toll-like receptor 4 (TLR4) and CD14, receptors on the Kupffer cell that internalize

APPL2 (415 words) [view diff] exact match in snippet view article find links to article

migration signaling adiponectin-activated signaling pathway regulation of toll-like receptor 4 signaling pathway cellular response to hepatocyte growth factor

IFI16 (1,383 words) [view diff] exact match in snippet view article find links to article

Caneparo V, Raviola S, Debernardi I, Colangelo D, et al. (2020) Toll-like receptor 4-mediated inflammation triggered by extracellular IFI16 is enhanced

IRF5 (1,430 words) [view diff] exact match in snippet view article find links to article

"The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling". The Journal of Biological Chemistry. 280 (17): 17005–17012

Roman Dziarski (5,581 words) [view diff] exact match in snippet view article find links to article

"Peptidoglycan- and lipoteichoic acid-induced cell activation is mediated by toll-like receptor 2". The Journal of Biological Chemistry. 274 (25): 17406–17409. doi:10

Wolfiporia extensa (1,013 words) [view diff] case mismatch in snippet view article find links to article

(2009-07-22). "A Novel Immunomodulatory Protein from Poria cocos Induces Toll-like Receptor 4-Dependent Activation within Mouse Peritoneal Macrophages". Journal

Tivadar Tulassay (328 words) [view diff] exact match in snippet view article find links to article

the rat kidney (co-author, 2004) Increased mucosal expression of Toll-like receptor (TLR)2 and TLR4 in coeliac disease (co-author, 2007) Index: Lemond

Fibrinogen gamma chain (471 words) [view diff] exact match in snippet view article find links to article

adhesion platelet aggregation signal transduction platelet activation toll-like receptor signaling pathway platelet maturation cellular response to interleukin-1

Caveolin 1 (1,555 words) [view diff] exact match in snippet view article find links to article

to transforming growth factor beta stimulus positive regulation of toll-like receptor 3 signaling pathway regulation of cytosolic calcium ion concentration

Flufftail (975 words) [view diff] exact match in snippet view article find links to article

Kotze, Antoinette (2016-11-09). "Lack of diversity at innate immunity Toll-like receptor genes in the Critically Endangered White-winged Flufftail (Sarothrura

OTUD4 (649 words) [view diff] exact match in snippet view article find links to article

deubiquitination proteolysis immune system process negative regulation of toll-like receptor signaling pathway innate immune response protein K63-linked deubiquitination

MAP3K3 (1,820 words) [view diff] exact match in snippet view article find links to article

(Jan 2004). "Differential regulation of interleukin 1 receptor and Toll-like receptor signaling by MEKK3". Nature Immunology. 5 (1): 98–103. doi:10.1038/ni1014

NFKBIL1 (758 words) [view diff] exact match in snippet view article find links to article

regulation of tumor necrosis factor production negative regulation of toll-like receptor signaling pathway I-kappaB kinase/NF-kappaB signaling negative regulation

Serum amyloid A1 (4,261 words) [view diff] exact match in snippet view article find links to article

2009). "Serum amyloid A induces G-CSF expression and neutrophilia via Toll-like receptor 2". Blood. 113 (2): 429–37. doi:10.1182/blood-2008-03-139923. PMC 2615655

Cathepsin L1 (1,708 words) [view diff] exact match in snippet view article find links to article

antigen via MHC class II extracellular matrix disassembly proteolysis toll-like receptor signaling pathway cellular response to thyroid hormone stimulus collagen

Hermann Wagner (888 words) [view diff] exact match in snippet view article find links to article

March 2004). "Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8". Science. 303 (5663): 1526–1529. Bibcode:2004Sci...303.1526H

GRAMD4 (240 words) [view diff] exact match in snippet view article find links to article

cysteine-type endopeptidase activity involved in apoptotic process negative regulation of toll-like receptor 9 signaling pathway Sources:Amigo / QuickGO

Interleukin 23 (2,186 words) [view diff] exact match in snippet view article find links to article

PMC 1782263. PMID 16630024. Re F, Strominger JL (October 2001). "Toll-like receptor 2 (TLR2) and TLR4 differentially activate human dendritic cells".

G. Dhinakar Raj (1,286 words) [view diff] exact match in snippet view article find links to article

Dhanasekaran, S.; Tirumurugaan, K.G.; Raja, A. (2012). "Comparative in vitro toll-like receptor ligand induced cytokine profiles of Toda and Murrah buffaloes—Identification

GFI1 (1,436 words) [view diff] exact match in snippet view article find links to article

development regulation of transcription, DNA-templated regulation of toll-like receptor signaling pathway regulation of histone H3-K4 methylation negative

Richard Bonneau (880 words) [view diff] exact match in snippet view article find links to article

Smith KD, Bonneau R, Strong RK, Aderem A. A conserved surface on Toll-like receptor 5 recognizes bacterial flagellin. (2007) J Exp Med. Feb 19;204(2):393-403

PIK3C3 (901 words) [view diff] exact match in snippet view article find links to article

endosome transport phosphatidylinositol biosynthetic process cell cycle toll-like receptor 9 signaling pathway macroautophagy regulation of protein secretion

Phytolacca americana (4,372 words) [view diff] case mismatch in snippet view article find links to article

Parcina, Marijo; Heeg, Klaus (2012-01-04). "Poke Weed Mitogen Requires Toll-Like Receptor Ligands for Proliferative Activity in Human and Murine B Lymphocytes"

TRIL (gene) (541 words) [view diff] exact match in snippet view article

involved in immune response innate immune response inflammatory response toll-like receptor 4 signaling pathway immune system process Sources:Amigo / QuickGO

MAPKAPK2 (1,726 words) [view diff] exact match in snippet view article find links to article

response macropinocytosis regulation of tumor necrosis factor production toll-like receptor signaling pathway intracellular signal transduction Sources:Amigo

OSCAR (gene) (583 words) [view diff] exact match in snippet view article

induces survival and maturation of dendritic cells and modulates Toll-like receptor responses". Blood. 105 (9): 3623–32. doi:10.1182/blood-2004-07-2809

LUC7L3 (648 words) [view diff] exact match in snippet view article find links to article

Brown V, Brown RA, Ozinsky A, et al. (2006). "Binding specificity of Toll-like receptor cytoplasmic domains". Eur. J. Immunol. 36 (3): 742–53. doi:10.1002/eji

Collectin-12 (593 words) [view diff] exact match in snippet view article find links to article

exogenous dsRNA phagocytosis, recognition innate immune response toll-like receptor 3 signaling pathway protein homooligomerization regulation of immune

Liver X receptor alpha (1,641 words) [view diff] exact match in snippet view article find links to article

complex nucleus cytoplasm Biological process positive regulation of toll-like receptor 4 signaling pathway sterol homeostasis negative regulation of pancreatic

Death receptor 3 (1,592 words) [view diff] case mismatch in snippet view article find links to article

in antigen presenting cells and some endothelial cells following Toll-Like Receptor or Fc receptor activation. This receptor has been shown to signal

Neuroimmunology (2,794 words) [view diff] no match in snippet view article find links to article

be linked to inflammatory markers. Studies have demonstrated that Toll like-receptor (TLR4) is critically involved in neuroinflammation and T cell recruitment

F8A1 (791 words) [view diff] exact match in snippet view article find links to article

Ozinsky A, Hesselberth JR, Fields S (2006). "Binding specificity of Toll-like receptor cytoplasmic domains". Eur. J. Immunol. 36 (3): 742–53. doi:10.1002/eji

Daniel J. Drucker (1,953 words) [view diff] exact match in snippet view article find links to article

2024). "Central glucagon-like peptide 1 receptor activation inhibits Toll-like receptor agonist-induced inflammation". Cell Metabolism. 36 (1): 130–143.e5

Altered Schaedler flora (2,578 words) [view diff] exact match in snippet view article find links to article

maturation of lymphoid follicles into large B cell clusters by the toll-like receptor signaling. In another study, the innate detection system generates

Fungal immunomodulatory protein (633 words) [view diff] exact match in snippet view article find links to article

2009). "A novel immunomodulatory protein from Poria cocos induces Toll-like receptor 4-dependent activation within mouse peritoneal macrophages". Journal

CYP1A1 (1,829 words) [view diff] case mismatch in snippet view article find links to article

intestine, but not the liver, CYP1A1 expression moreover depends on TOLL-like receptor 2 (TLR2), which recognizes bacterial surface structures such as lipoteichoic

RAB11FIP2 (1,027 words) [view diff] exact match in snippet view article find links to article

protein localization to plasma membrane phagocytosis TRAM-dependent toll-like receptor 4 signaling pathway positive regulation of GTPase activity Sources:Amigo

T helper 3 cell (1,235 words) [view diff] exact match in snippet view article find links to article

(transforming growth factor-β1) expression on CD4+ T cells reduces Toll-like receptor 4 ligand-induced tumour necrosis factor-α production in a transforming

P38 mitogen-activated protein kinases (1,385 words) [view diff] exact match in snippet view article find links to article

key regulator of proinflammatory cytokine up-regulation induced by toll-like receptor (TLR) ligands or beta-amyloid (Aβ)". Journal of Neuroinflammation

Novimmune (361 words) [view diff] case mismatch in snippet view article find links to article

- Bloomberg". www.bloomberg.com. "First in Human Study of an Anti-Toll-like Receptor 4 (TLR4) Monoclonal Antibody (NI-0101) in Adult Healthy Volunteers

LGR4 (294 words) [view diff] exact match in snippet view article find links to article

osteoblast differentiation bone mineralization negative regulation of toll-like receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor

Alloimmunity (2,381 words) [view diff] exact match in snippet view article find links to article

WE, Goldstein DR (August 2007). "Neonatal B cells suppress innate toll-like receptor immune responses and modulate alloimmunity". J. Immunol. 179 (3):

RAB11A (1,394 words) [view diff] exact match in snippet view article find links to article

TE, Bakke O, Espevik T (October 2010). "The Rab11a GTPase controls Toll-like receptor 4-induced activation of interferon regulatory factor-3 on phagosomes"

Dermatomyositis (2,761 words) [view diff] exact match in snippet view article find links to article

adrenocorticotropic hormone gel (Phase IV, open label), IMO-8400, an antagonist of Toll-like receptor 7,8 and 9 (Ph II), abatacept (Phase IV, open label), and sodium thiosulfate

Ischemic preconditioning (1,235 words) [view diff] exact match in snippet view article find links to article

LN, Zhu W, Li Y, Xu XL, Guo LJ, Lu Q, Wang J (2014). "Astrocytic Toll-like receptor 3 is associated with ischemic preconditioning-induced protection against

Mihai Netea (2,194 words) [view diff] exact match in snippet view article find links to article

Diet and Health" (400.000 euro) EP2076282 – Novel antagonists of the Toll-like receptor 4. EP6030245 - Novel method for diagnosing Lyme disease using a cellular

Catastrophic antiphospholipid syndrome (1,350 words) [view diff] exact match in snippet view article find links to article

favors a hypercoagulable state, which has been noted to activate toll-like receptor 4 resulting in what is known as a cytokine storm or a thrombotic storm

Katherine A. Fitzgerald (907 words) [view diff] exact match in snippet view article find links to article

McMurray, Diane (2001). "Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction". Nature. 413 (6851): 78–83. Bibcode:2001Natur

UBQLN1 (1,428 words) [view diff] exact match in snippet view article find links to article

positive regulation of protein ubiquitination negative regulation of toll-like receptor 3 signaling pathway cellular response to hypoxia autophagosome maturation

Benzo(a)pyrene (2,662 words) [view diff] case mismatch in snippet view article

circulation. Intestinal, but not hepatic, expression of CYP1A1 depends on TOLL-like receptor 2 (TLR2), which is a eukaryotic receptor for bacterial surface structures

CD300LB (gene) (411 words) [view diff] case mismatch in snippet view article

(June 2016). "Lipopolysaccharide-Induced CD300b Receptor Binding to Toll-like Receptor 4 Alters Signaling to Drive Cytokine Responses that Enhance Septic

Benzo(a)pyrene (2,662 words) [view diff] case mismatch in snippet view article

circulation. Intestinal, but not hepatic, expression of CYP1A1 depends on TOLL-like receptor 2 (TLR2), which is a eukaryotic receptor for bacterial surface structures

IRF4 (2,598 words) [view diff] exact match in snippet view article find links to article

DNA-templated peptidyl-lysine methylation negative regulation of toll-like receptor signaling pathway type I interferon signaling pathway histone H3 acetylation

Electrospray (1,991 words) [view diff] case mismatch in snippet view article find links to article

2174/1573413052953192. Duong, A.D. (2013). "Electrospray Encapsulation of Toll-Like Receptor Agonist Resiquimod in Polymer Microparticles for the Treatment of

BCL10 (1,813 words) [view diff] exact match in snippet view article find links to article

signaling pathway negative regulation of mature B cell apoptotic process toll-like receptor signaling pathway positive regulation of transcription, DNA-templated

Nventa Biopharmaceuticals Corporation (803 words) [view diff] exact match in snippet view article find links to article

specific diseases. Nventa is developing HspE7 in combination with the Toll-like receptor 3 (TLR3) agonist adjuvant Poly-ICLC for multiple indications, including

Tyrosine-protein kinase SYK (2,083 words) [view diff] exact match in snippet view article find links to article

activity protein kinase binding nucleotide binding phosphatase binding Toll-like receptor binding phosphotyrosine residue binding SH2 domain binding interleukin-15

Douglas R. Green (954 words) [view diff] exact match in snippet view article find links to article

M; Tanaka, K; Cleveland, J. L.; Withoff, S; Green, D. R. (2007). "Toll-like receptor signalling in macrophages links the autophagy pathway to phagocytosis"

Non-celiac gluten sensitivity (7,377 words) [view diff] exact match in snippet view article find links to article

part of the plant's natural defence against insects and may cause toll-like receptor 4 (TLR4)-mediated intestinal inflammation in humans. These TLR4-stimulating

Dipyaman Ganguly (1,508 words) [view diff] case mismatch in snippet view article find links to article

(May 2020). "A Chemical Switch for Transforming a Purine Agonist for Toll-like Receptor 7 to a Clinically Relevant Antagonist". Journal of Medicinal Chemistry

Adenoid hypertrophy (2,719 words) [view diff] exact match in snippet view article find links to article

öZdaş, Talih; öZdaş, Sibel (2016). "The common genetic variants of toll-like receptor and susceptibilityto adenoid hypertrophy: a hospital-based cohort

LGMN (771 words) [view diff] exact match in snippet view article find links to article

vacuolar protein processing receptor catabolic process proteolysis toll-like receptor signaling pathway proteolysis involved in cellular protein catabolic

Tretinoin (2,908 words) [view diff] exact match in snippet view article find links to article

involved in inflammation. Retinoids also down-regulate expression of toll-like receptor (TLR)-2, which has been implicated in the inflammatory response in

APPL1 (1,118 words) [view diff] exact match in snippet view article find links to article

migration signaling adiponectin-activated signaling pathway regulation of toll-like receptor 4 signaling pathway cellular response to hepatocyte growth factor

GPS2 (gene) (1,333 words) [view diff] exact match in snippet view article

lipid metabolic process B cell differentiation negative regulation of toll-like receptor signaling pathway positive regulation of peroxisome proliferator activated

Burkholderia mallei (2,962 words) [view diff] case mismatch in snippet view article find links to article

"Structural Relationship of the Lipid A Acyl Groups to Activation of Murine Toll-Like Receptor 4 by Lipopolysaccharides from Pathogenic Strains of Burkholderia mallei

Interleukin 26 (2,809 words) [view diff] exact match in snippet view article find links to article

type I interferon by plasmacytoid dendritic cells via activation of Toll-like receptor 9, but independently of the IL-26 receptor. Monocytes infected with

Tomáš Cihlář (1,041 words) [view diff] exact match in snippet view article find links to article

capsids. Recently, these entail low molecular weight agonists of TLR7 (toll-like receptor 7). TLR7 receptors recognize single-stranded RNA in endosomes and

CD200R1 (1,187 words) [view diff] exact match in snippet view article find links to article

impaired in membrane glycoprotein CD200-deficient mice: a role for Toll-like receptor activation". The Journal of Biological Chemistry. 286 (40): 34722–32

RIPK3 (1,078 words) [view diff] exact match in snippet view article find links to article

Kelliher M, et al. (May 2004). "RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B activation" (PDF). Nature Immunology. 5 (5):

Clindamycin/benzoyl peroxide (1,532 words) [view diff] exact match in snippet view article find links to article

"Review of the innate immune response in acne vulgaris: activation of Toll-like receptor 2 in acne triggers inflammatory cytokine responses". Dermatology.

CD19 (3,916 words) [view diff] exact match in snippet view article find links to article

Conley ME, Reisli I, Franco JL, et al. (March 2016). "CD19 controls Toll-like receptor 9 responses in human B cells". The Journal of Allergy and Clinical

MAP3K1 (3,167 words) [view diff] exact match in snippet view article find links to article

cytoplasm cytosol Biological process phosphorylation MyD88-dependent toll-like receptor signaling pathway Fc-epsilon receptor signaling pathway protein phosphorylation

Fibrinogen beta chain (972 words) [view diff] exact match in snippet view article find links to article

aggregation signal transduction induction of bacterial agglutination platelet activation toll-like receptor signaling pathway Sources:Amigo / QuickGO

TANK (gene) (1,420 words) [view diff] exact match in snippet view article

cytosol protein-containing complex Biological process TRIF-dependent toll-like receptor signaling pathway signal transduction positive regulation of ubiquitin-specific

Statera BioPharma (858 words) [view diff] case mismatch in snippet view article find links to article

process for human pharmaceuticals. Entolimod acts through activation of Toll-like Receptor 5 to mobilize antitumor immune response and reduce radiation effects

Mitochondrial biogenesis (2,583 words) [view diff] exact match in snippet view article find links to article

(February 2015). "Suppression of mitochondrial biogenesis through toll-like receptor 4-dependent mitogen-activated protein kinase kinase/extracellular

Sarcoidosis (12,856 words) [view diff] exact match in snippet view article find links to article

Crouser ED (February 2013). "Nicotine treatment improves Toll-like receptor 2 and Toll-like receptor 9 responsiveness in active pulmonary sarcoidosis". Chest

Cathepsin S (2,319 words) [view diff] exact match in snippet view article find links to article

II protein processing extracellular matrix disassembly proteolysis toll-like receptor signaling pathway antigen processing and presentation of peptide antigen

Curli (1,701 words) [view diff] case mismatch in snippet view article find links to article

is recognized in the innate immune system and activates the TLR2 (Toll-Like Receptor 2). This then causes a downstream response by producing a pro-inflammatory

NLRP1 (2,089 words) [view diff] exact match in snippet view article find links to article

LI, Keestra AM, et al. (March 2011). "Cleavage and activation of a Toll-like receptor by microbial proteases". Proceedings of the National Academy of Sciences

Major histocompatibility complex and sexual selection (4,314 words) [view diff] exact match in snippet view article find links to article

Tschirren, Barbara (2014-08-01). "Naturally occurring Toll-like receptor 11 (TLR11) and Toll-like receptor 12 (TLR12) polymorphisms are not associated with

Mannose receptor (3,688 words) [view diff] exact match in snippet view article find links to article

HEK 293 cells co-transfected with human mannose receptor and human Toll-like receptor 2 cDNA are able to secrete IL-8 in response to P. carinii infection

NOX2 (2,434 words) [view diff] case mismatch in snippet view article find links to article

Inflammation and Hypotension in Endotoxemia by Controlling Expression of Toll-Like Receptor 4". Shock. 56 (2): 268–277. doi:10.1097/SHK.0000000000001706. PMC 8284354

Apilimod (658 words) [view diff] exact match in snippet view article find links to article

the small molecular IL-12/IL-23 inhibitor apilimod and a player in Toll-like receptor signaling". Chemistry & Biology. 20 (7): 912–21. doi:10.1016/j.chembiol

Paola Ricciardi-Castagnoli (1,085 words) [view diff] exact match in snippet view article find links to article

Beutler, B (2000). "Physical contact between lipopolysaccharide and Toll-like receptor 4 revealed by genetic complementation". Proceedings of the National

Cathryn Nagler (695 words) [view diff] case mismatch in snippet view article find links to article

Steven; Shi, Hai Ning; Nagler-Anderson, Cathryn (June 1, 2004). "Toll-Like Receptor 4 Signaling by Intestinal Microbes Influences Susceptibility to Food

NLRP12 (2,187 words) [view diff] exact match in snippet view article find links to article

et al. (2006). "The CATERPILLER protein monarch-1 is an antagonist of toll-like receptor-, tumor necrosis factor alpha-, and Mycobacterium tuberculosis-induced

Caspase 1 (2,398 words) [view diff] exact match in snippet view article find links to article

Balosso S, Sanchez MA, Bartfai T (October 2011). "IL-1 receptor/Toll-like receptor signaling in infection, inflammation, stress and neurodegeneration

Mollaret's meningitis (1,604 words) [view diff] case mismatch in snippet view article find links to article

Ahmad-Nejad; Michael Neumaier; Michael G. Hennerici; Marc Fatar (2010). "Toll-Like Receptor 3 Immune Deficiency May Be Causative for HSV-2-Associated Mollaret

Burkitt lymphoma (4,609 words) [view diff] exact match in snippet view article find links to article

reactivation of latent EBV and also MYC translocations via activation of the toll-like receptor 9. Malaria also promotes B-cell proliferation by altering the regular

S100A1 (4,914 words) [view diff] exact match in snippet view article find links to article

released from ischemic cardiomyocytes and signals myocardial damage via Toll-like receptor 4". EMBO Molecular Medicine. 6 (6): 778–94. doi:10.15252/emmm.201303498

Surfactant protein D (1,686 words) [view diff] exact match in snippet view article find links to article

immune response lung alveolus development innate immune response toll-like receptor signaling pathway induction of bacterial agglutination regulation

Amphotericin B (4,077 words) [view diff] exact match in snippet view article find links to article

antifungal drug amphotericin B promotes inflammatory cytokine release by a Toll-like receptor- and CD14-dependent mechanism". The Journal of Biological Chemistry

HDAC7 (2,058 words) [view diff] exact match in snippet view article find links to article

KM, Fairlie DP, Sweet MJ (2013). "Histone deacetylase 7 promotes Toll-like receptor 4-dependent proinflammatory gene expression in macrophages". The Journal

NFKBIZ (1,238 words) [view diff] exact match in snippet view article find links to article

lipopolysaccharide induces mRNA expression of an IkappaB MAIL through toll-like receptor 4". The Journal of Veterinary Medical Science. 64 (5): 419–22. doi:10

Adeno-associated virus (8,540 words) [view diff] exact match in snippet view article find links to article

longer. In-vivo studies indicate that AAV vectors interact with the Toll-like receptor (TLR)9- and TLR2-MyD88 pathways to trigger the innate immune response

Arrestin beta 2 (1,965 words) [view diff] exact match in snippet view article find links to article

development negative regulation of GTPase activity negative regulation of toll-like receptor signaling pathway protein ubiquitination positive regulation of DNA

Bacterial morphological plasticity (3,631 words) [view diff] exact match in snippet view article find links to article

response to host innate immune response (more exactly in response to Toll-like receptor 4-TLR4). TLR-4 is stimulated by the lipopolysaccharide (LPS) and recruits

Alison Rich (academic) (531 words) [view diff] exact match in snippet view article

VP, Seymour GJ, Rich AM. Forkhead box-P3+ regulatory T cells and toll-like receptor 2 co-expression in oral squamous cell carcinoma. Acta Histochemica

MS100a7a15 (914 words) [view diff] exact match in snippet view article find links to article

antimicrobial protein of the skin: regulation by E. coli through Toll-like receptor 4". The Journal of Investigative Dermatology. 127 (11): 2596–604.

Cutibacterium acnes (4,096 words) [view diff] exact match in snippet view article find links to article

"Review of the innate immune response in acne vulgaris: activation of Toll-like receptor 2 in acne triggers inflammatory cytokine responses". Dermatology.

DHX36 (1,267 words) [view diff] exact match in snippet view article find links to article

A, Hesselberth JR, Fields S (March 2006). "Binding specificity of Toll-like receptor cytoplasmic domains". European Journal of Immunology. 36 (3): 742–53

FLOT2 (1,370 words) [view diff] exact match in snippet view article find links to article

positive regulation of establishment of T cell polarity regulation of toll-like receptor 3 signaling pathway regulation of heterotypic cell-cell adhesion protein

Igor P. Kaidashev (1,323 words) [view diff] exact match in snippet view article find links to article

109-114 Kutsenko NL, Izmailova OV, Vesnina LE, Kaidashev IP. Role of toll-like receptor 2 and 4 gene polymorphisms in the development of allergic diseases

Mitochondrial antiviral-signaling protein (1,931 words) [view diff] exact match in snippet view article find links to article

Double stranded RNA viruses are recognized by either the transmembrane toll-like receptor 3 (TLR3) or by one of two cytosolic proteins, retinoic acid-inducible

Mesenchymal stem cell (4,871 words) [view diff] no match in snippet view article find links to article

Escherichia coli is mediated by secretion of beta- defensin- 2 via toll- like receptor 4 signalling". Cellular Microbiology. 18 (3): 424–36. doi:10.1111/cmi

Jawahar L. Mehta (1,201 words) [view diff] exact match in snippet view article find links to article

Ding Z, Liu S, ....Mehta JL. Lectin-like ox-LDL receptor-1 (LOX-1) - toll-like receptor 4 (TLR4) interaction and autophagy in CATH.a differentiated cells

(+)-Benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide (1,494 words) [view diff] case mismatch in snippet view article

circulation. Intestinal, but not hepatic, expression of CYP1A1 depends on TOLL-like receptor 2 (TLR2), which is a eucaryotic receptor for bacterial surface structures

Tight junction protein ZO-1 (2,034 words) [view diff] exact match in snippet view article find links to article

35179. PMID 10575001. Cario E, Gerken G, Podolsky DK (July 2004). "Toll-like receptor 2 enhances ZO-1-associated intestinal epithelial barrier integrity

Cord factor (3,846 words) [view diff] exact match in snippet view article find links to article

pro-inflammatory cytokines as well. However, there is also evidence that toll-like receptor 2 (TLR2) in conjunction with the protein MyD-88 is responsible for

Halothane (2,752 words) [view diff] exact match in snippet view article find links to article

anesthetics isoflurane and sevoflurane directly target and attenuate Toll-like receptor 4 system". FASEB Journal. 33 (12): 14528–41. doi:10.1096/fj.201901570R

Capnocytophaga canimorsus (2,869 words) [view diff] exact match in snippet view article find links to article

IL-8, IL-6 and IL-1α, interferon-γ, and nitric oxide. In addition, toll-like receptor 4 (TLR4) normally recognizes pathogens and begins a signalling cascade

Ulf Landmesser (1,264 words) [view diff] case mismatch in snippet view article find links to article

High-Density Lipoprotein Induces Endothelial Dysfunction via Activation of Toll-like Receptor-2." Immunity 38, no. 4 (18 April 2013): 754–68. doi:10.1016/j.immuni

BPIFB1 (1,221 words) [view diff] exact match in snippet view article find links to article

response in mucosa innate immune response negative regulation of toll-like receptor 4 signaling pathway immune system process antimicrobial humoral response

Alkaline phosphatase (6,147 words) [view diff] exact match in snippet view article find links to article

well as in suppressing inflammation via repression of the downstream Toll-like receptor (TLR)-4-dependent and MyD88-dependent inflammatory cascade. It dephosphorylates

TAB1 (2,197 words) [view diff] exact match in snippet view article find links to article

signaling pathway in utero embryonic development MyD88-dependent toll-like receptor signaling pathway coronary vasculature development Fc-epsilon receptor

Antonio Lanzavecchia (1,709 words) [view diff] exact match in snippet view article find links to article

A.; Bertoni, F.; Sallusto, F.; Lanzavecchia, A. (2005). "Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1 -polarizing

Subunit vaccine (6,722 words) [view diff] exact match in snippet view article find links to article

Vi capsular antigen of Salmonella enterica serotype Typhi reduces Toll-like receptor-dependent interleukin-8 expression in the intestinal mucosa". Infection

S100A7A (1,598 words) [view diff] exact match in snippet view article find links to article

antimicrobial protein of the skin: regulation by E. coli through Toll-like receptor 4". J. Invest. Dermatol. 127 (11): 2596–604. doi:10.1038/sj.jid.5700946

Phosphoinositide-dependent kinase-1 (2,127 words) [view diff] exact match in snippet view article find links to article

apoptotic process focal adhesion assembly negative regulation of toll-like receptor signaling pathway peptidyl-serine phosphorylation regulation of endothelial

Jennifer Stow (1,598 words) [view diff] case mismatch in snippet view article find links to article

Stow, J.L. (2016). "Distinct Roles for APPL1 and APPL2 in Regulating Toll-like Receptor 4 Signaling in Macrophages: APPL Regulation of TLR4 Signaling". Traffic

Detlef Schuppan (1,365 words) [view diff] exact match in snippet view article find links to article

trypsin inhibitors drive intestinal inflammation via activation of toll-like receptor 4". The Journal of Experimental Medicine. 209 (13): 2395–2408. doi:10

FCRL3 (1,917 words) [view diff] exact match in snippet view article find links to article

production positive regulation of B cell proliferation regulation of toll-like receptor 9 signaling pathway positive regulation of MAPK cascade regulation

Small interfering RNA (6,837 words) [view diff] exact match in snippet view article find links to article

gene I (RIG-I) may also be involved. The induction of cytokines via toll-like receptor 7 (TLR7) has also been described. Chemical modification of siRNA is

Epizootic hemorrhagic disease (1,941 words) [view diff] case mismatch in snippet view article find links to article

Novakofski JE, et al. (February 2023). "The Impact of Variation in the Toll-like Receptor 3 Gene on Epizootic Hemorrhagic Disease in Illinois Wild White-Tailed

Innate Immunotherapeutics (1,971 words) [view diff] exact match in snippet view article find links to article

T-cell-mediated autoimmune responses in EAE by simultaneously activating innate Toll-like receptor 9 and nucleotide-binding oligomerization domain-containing protein

Fc receptor (4,735 words) [view diff] case mismatch in snippet view article find links to article

"FcγRIIIa-Syk Co-signal Modulates CD4+ T-cell Response and Up-regulates Toll-like Receptor (TLR) Expression". J. Biol. Chem. 291 (3): 1368–86. doi:10.1074/jbc

Nickel allergy (3,598 words) [view diff] exact match in snippet view article find links to article

Th17, Th22, Th1/IFN and the innate immune responses consistent with toll-like receptor 4. Nickel has a wide utility of application in manufactured metals

ABO (gene) (2,172 words) [view diff] exact match in snippet view article

2007). "Translational mini-review series on Toll-like receptors: Toll-like receptor ligands as novel pharmaceuticals for allergic disorders". Clinical

Cathelicidin antimicrobial peptide (3,739 words) [view diff] exact match in snippet view article find links to article

Stenger S, Li H, Wenzel L, Tan BH, Krutzik SR, et al. (March 2006). "Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response".

Reticulon 4 (1,924 words) [view diff] exact match in snippet view article find links to article

membrane organization blastocyst formation positive regulation of toll-like receptor 9 signaling pathway protein localization to lysosome cellular sphingolipid

ABO blood group system (6,008 words) [view diff] exact match in snippet view article find links to article

2007). "Translational mini-review series on Toll-like receptors: Toll-like receptor ligands as novel pharmaceuticals for allergic disorders". Clinical

University of Texas Southwestern Medical Center (4,942 words) [view diff] exact match in snippet view article find links to article

Nobel Prize in Physiology or Medicine for his discovery that the Toll-like receptor 4 (TLR4) is the membrane-spanning component of the mammalian lipopolysaccharide

Apolipoprotein B (4,890 words) [view diff] exact match in snippet view article find links to article

cholesterol efflux post-embryonic development lipoprotein transport toll-like receptor signaling pathway response to estradiol membrane organization chylomicron

Erythrina alkaloids (1,291 words) [view diff] case mismatch in snippet view article find links to article

Kanki; Hayashi, Masahiko (2013). "Inhibitory Effect of Erythraline on Toll-Like Receptor Signaling Pathway in RAW264.7 Cells". Biological and Pharmaceutical

Curcumin synthase (1,624 words) [view diff] exact match in snippet view article find links to article

2002. PMC 118079. PMID 12097249. Zhang G, Ghosh S (January 2001). "Toll-like receptor-mediated NF-kappaB activation: a phylogenetically conserved paradigm

Gabriella Campadelli-Fiume (1,624 words) [view diff] case mismatch in snippet view article find links to article

PMID 3561254. Herpes Simplex Virus Glycoproteins gH/gL and gB Bind Toll-Like Receptor 2, and Soluble gH/gL Is Sufficient To Activate NF-κB Singh GN, Gupta

Lactoferrin (5,692 words) [view diff] exact match in snippet view article find links to article

regulation of I-kappaB kinase/NF-kappaB signaling positive regulation of toll-like receptor 4 signaling pathway siderophore-dependent iron import into cell antimicrobial

P110δ (2,500 words) [view diff] no match in snippet view article find links to article

species in neutrophils. p110δ controls lipopolysaccharide induced Toll-like-receptor-4 mediated innate immune responses in dendritic cells and mice carrying

Systems immunology (3,351 words) [view diff] exact match in snippet view article find links to article

; 16 April 2019 (2019). "Cooperation between T cell receptor and Toll-like receptor 5 signaling for CD4+ T cell activation" (PDF). Science Signaling.

Metatranscriptomics (4,188 words) [view diff] exact match in snippet view article find links to article

1038/nri3430. PMID 23618829. S2CID 205491968. Abreu MT (February 2010). "Toll-like receptor signalling in the intestinal epithelium: how bacterial recognition

Özlem Türeci (3,520 words) [view diff] exact match in snippet view article find links to article

Kerstin C Walzer; et al. (19 April 2019). "Intravenous delivery of the toll-like receptor 7 agonist SC1 confers tumor control by inducing a CD8+ T cell response"

Biodiversity and drugs (2,152 words) [view diff] exact match in snippet view article find links to article

Hadaś, Edward (2019). "The modulatory effect of Artemisia annua L. on toll-like receptor expression in Acanthamoeba infected mouse lungs". Experimental Parasitology

Leishmania (6,163 words) [view diff] exact match in snippet view article find links to article

over the outside of the cell. Lipophosphoglycan is a trigger for toll-like receptor 2, a signalling receptor involved in triggering an innate immune response

Yellow fever (12,171 words) [view diff] exact match in snippet view article find links to article

"Sensing of viral infection and activation of innate immunity by toll-like receptor 3". Clinical Microbiology Reviews. 21 (1): 13–25. doi:10.1128/CMR

Nicotinamide phosphoribosyltransferase (3,227 words) [view diff] case mismatch in snippet view article find links to article

CL, Danilov SM, Zhou T, Chiang ET, et al. (August 2015). "Unique Toll-Like Receptor 4 Activation by NAMPT/PBEF Induces NFκB Signaling and Inflammatory

GroEL (5,440 words) [view diff] exact match in snippet view article find links to article

maturation positive regulation of macrophage activation MyD88-dependent toll-like receptor signaling pathway isotype switching to IgG isotypes B cell activation

PRDM1 (2,688 words) [view diff] exact match in snippet view article find links to article

DNA (abundant in bacterial genomes), and cancer inflammation via Toll-like receptor (TLR) 3, TLR-4, TLR-9, and STAT signaling, respectively. The increased

Coeliac disease (15,720 words) [view diff] exact match in snippet view article find links to article

disease, a subset of autoantibodies against transglutaminase binds toll-like receptor 4 and induces activation of monocytes". PLOS Med. 3 (9): e358. doi:10

PRKCE (6,268 words) [view diff] exact match in snippet view article find links to article

positive regulation of synaptic transmission, GABAergic TRAM-dependent toll-like receptor 4 signaling pathway locomotory exploration behavior platelet activation

Antimicrobial peptides (6,549 words) [view diff] no match in snippet view article find links to article

is an immunomodulator that acts through p62, a protein involved in toll like receptor based signalling of infection. The peptide is being examined in a

Surfactant protein A1 (3,387 words) [view diff] exact match in snippet view article find links to article

respiratory gaseous exchange by respiratory system lipid transport toll-like receptor signaling pathway opsonization surfactant homeostasis positive regulation

Vein graft failure (2,577 words) [view diff] exact match in snippet view article find links to article

IE; Fischer, JW; Jukema, JW; Niessen, HW; Quax, PH (May 2011). "Toll-like receptor 4 is involved in human and mouse vein graft remodeling, and local

Morphine (13,848 words) [view diff] exact match in snippet view article find links to article

pathway. Usually, the p38 within the dendritic cell expresses TLR 4 (toll-like receptor 4), which is activated through the ligand LPS (lipopolysaccharide)

Estrogen receptor alpha (6,133 words) [view diff] exact match in snippet view article find links to article

regulation of inflammatory response response to estradiol regulation of toll-like receptor signaling pathway regulation of transcription by RNA polymerase II

Jeffrey Flier (3,560 words) [view diff] exact match in snippet view article find links to article

inflammatory phenomena in metabolic disease, Flier helped establish that Toll-like receptor 4 (TLR4) activation in adipocytes and macrophages mediates inflammation

Surfactant protein A2 (3,608 words) [view diff] exact match in snippet view article find links to article

Biological process respiratory gaseous exchange by respiratory system toll-like receptor signaling pathway surfactant homeostasis positive regulation of phagocytosis

Kishor Wasan (1,315 words) [view diff] case mismatch in snippet view article find links to article

Carlos G.; et al. (August 1, 2008). "Discovery and Development of Toll-Like Receptor 4 (TLR4) Antagonists: A New Paradigm for Treating Sepsis and Other

Human endogenous retrovirus-W (4,813 words) [view diff] exact match in snippet view article find links to article

envelope protein is a potent, endogenous and pathogenic agonist of human toll-like receptor 4: Relevance of GNbAC1 in multiple sclerosis treatment". Journal of

S. Murty Srinivasula (1,517 words) [view diff] exact match in snippet view article find links to article

Srinivasa M. (25 January 2011). "Nrf2-mediated induction of p62 controls Toll-like receptor-4-driven aggresome-like induced structure formation and autophagic

DSCAM (3,755 words) [view diff] exact match in snippet view article find links to article

0127.x. PMID 15199960. S2CID 6188654. Akira, S; Takeda K (2004). "Toll-like receptor signalling". Nat Rev Immunol. 4 (7): 499–511. doi:10.1038/nri1391

High Affinity K+ transporter HAK5 (2,308 words) [view diff] exact match in snippet view article find links to article

which signals a downstream immune response. In animal cells the toll-like receptor TLR4 binds the bacterial PAMP LPS (lipopolysaccharide) and induces

Influenza vaccine (18,140 words) [view diff] case mismatch in snippet view article find links to article

Massari P (April 2014). "Immune Adjuvant Effect of Molecularly-defined Toll-Like Receptor Ligands". Vaccines. 2 (2): 323–53. doi:10.3390/vaccines2020323. PMC 4494261

Julie McElrath (4,118 words) [view diff] case mismatch in snippet view article find links to article

Mullins, James I; McElrath, M. Juliana; Lingappa, Jairam R (2014). "Toll-like Receptor Polymorphism Associations with HIV-1 Outcomes Among Sub-Saharan Africans"

RAGE (receptor) (6,865 words) [view diff] exact match in snippet view article

receptor is involved in activating signaling pathways such as MAPK and Toll-like receptor 4 (TLR4), which help modulate the inflammatory response to AGEs, thus

Management of tuberculosis (21,413 words) [view diff] exact match in snippet view article find links to article

Stenger S, Li H, Wenzel L, Tan BH, Krutzik SR, et al. (March 2006). "Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response".

Cytochrome b-245, alpha polypeptide (4,853 words) [view diff] exact match in snippet view article find links to article

stimulus hydrogen peroxide biosynthetic process positive regulation of toll-like receptor 2 signaling pathway positive regulation of superoxide anion generation

2012 in science (38,862 words) [view diff] case mismatch in snippet view article find links to article

2022-01-17. Hutchinson, M. R.; et al. (2012-08-15). "Opioid Activation of Toll-Like Receptor 4 Contributes to Drug Reinforcement". Journal of Neuroscience. 32

Itaconic acid (11,779 words) [view diff] exact match in snippet view article find links to article

"Systems biology approaches identify ATF3 as a negative regulator of Toll-like receptor 4". Nature. 441 (7090): 173–8. Bibcode:2006Natur.441..173G. doi:10

Peptidoglycan recognition protein (11,846 words) [view diff] exact match in snippet view article find links to article

protein 6 (zfPGRP6) mediated differentially expressed genes involved in Toll-like receptor signaling pathway and caused increased susceptibility to Flavobacterium

Peter Tontonoz (3,035 words) [view diff] exact match in snippet view article find links to article

Cheng; P, Tontonoz (October 19, 2003). "Crosstalk between LXR and toll-like receptor signaling mediates bacterial and viral antagonism of cholesterol metabolism"

Epigenetics of autoimmune disorders (7,834 words) [view diff] exact match in snippet view article find links to article

in regulating the immune system by providing negative feedback to toll-like receptor (TLR) signaling which is used to engage the innate immune response

Light-emitting diode therapy (4,551 words) [view diff] exact match in snippet view article find links to article

"Light-emitting diodes downregulate cathelicidin, kallikrein and toll-like receptor 2 expressions in keratinocytes and rosacea-like mouse skin". Experimental