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Longer titles found: Somatic mutation and recombination tests (view)

searching for Somatic mutation 121 found (157 total)

Evolution of ageing (6,801 words) [view diff] exact match in snippet view article find links to article

relationship between somatic mutation rate and lifespan across different mammalian species suggests that evolution may constrain somatic mutation rates, perhaps

Wellcome Sanger Institute (3,938 words) [view diff] case mismatch in snippet view article find links to article

people and engages in five main areas of research: Cancer, Ageing and Somatic Mutation; Cellular Genetics; Human Genetics; Parasite and Microbes; and the

Cancer Genome Project (1,664 words) [view diff] exact match in snippet view article find links to article

The Cancer Genome Project is part of the cancer, aging, and somatic mutation research based at the Wellcome Trust Sanger Institute in the United Kingdom

Myeloproliferative neoplasm (1,524 words) [view diff] exact match in snippet view article find links to article

uncontrolled. The overproduction of blood cells is often associated with a somatic mutation, for example in the JAK2, CALR, TET2, and MPL gene markers. In rare

Somatic hypermutation (1,178 words) [view diff] exact match in snippet view article find links to article

proliferation, the B-cell receptor locus undergoes an extremely high rate of somatic mutation that is at least 105–106 fold greater than the normal rate of mutation

Weismann barrier (867 words) [view diff] exact match in snippet view article find links to article

germline cells to somatic cells. This means that new information from somatic mutation is not passed on to the germline. This barrier concept implies that

Mutation frequency (674 words) [view diff] exact match in snippet view article find links to article

, & Luzzatto, L. (2005). A quantitative measurement for the human somatic mutation rate. Cancer Research, (65), 8111-8117. Peruzzi, B., Araten, D., Notaro

Melorheostosis (511 words) [view diff] exact match in snippet view article find links to article

can have the appearance of dripping candle wax. A randomly occurring somatic mutation of the MAP2K1 gene during fetal development is believed to be the cause

Alfred G. Knudson (940 words) [view diff] exact match in snippet view article find links to article

of gene mutation during cell division (a somatic mutation), and a model that requires only one somatic mutation per tumor in hereditary cases but requires

Outline of life extension (586 words) [view diff] exact match in snippet view article find links to article

Reliability theory of aging and longevity Reproductive-cell cycle theory Somatic mutation theory of aging Telomeric theory of aging Theory of programmed death

Mosaic (genetics) (2,658 words) [view diff] exact match in snippet view article

fertilized egg cell, due to mitotic errors at first or later cleavages. Somatic mutation leading to mosaicism is prevalent in the beginning and end stages of

MLH3 (1,528 words) [view diff] exact match in snippet view article find links to article

FS (May 2001). "Germline and somatic mutation analyses in the DNA mismatch repair gene MLH3: Evidence for somatic mutation in colorectal cancers". Human

NSDHL (998 words) [view diff] exact match in snippet view article find links to article

M400462-JLR200. PMID 15805545. Mehra S, Li L, Fan CY, et al. (2005). "A novel somatic mutation of the 3beta-hydroxysteroid dehydrogenase gene in sporadic cutaneous

SNV calling from NGS data (3,217 words) [view diff] exact match in snippet view article find links to article

A., Mardis, E. R., Ding, L., and Wilson, R. K. (2012). "VarScan 2: somatic mutation and copy number alteration discovery in cancer by exome sequencing"

Glycosylphosphatidylinositol (656 words) [view diff] exact match in snippet view article find links to article

paroxysmal nocturnal hemoglobinuria caused by a germline mutation and a somatic mutation in PIGT". Blood. 122 (7): 1312–5. doi:10.1182/blood-2013-01-481499

Carcinogenesis (13,967 words) [view diff] exact match in snippet view article find links to article

According to the prevailing accepted theory of carcinogenesis, the somatic mutation theory, mutations in DNA and epimutations that lead to cancer disrupt

SLC22A18 (671 words) [view diff] exact match in snippet view article find links to article

RJ, Brandenburg S, Lee MJ, Miller G, Feinberg AP (September 1998). "Somatic mutation of TSSC5, a novel imprinted gene from human chromosome 11p15.5". Cancer

GNAQ (1,478 words) [view diff] exact match in snippet view article find links to article

(May 23, 2013). "Sturge-Weber syndrome and port-wine stains caused by somatic mutation in GNAQ". The New England Journal of Medicine. 368 (21): 1971–9. doi:10

Elodea (659 words) [view diff] exact match in snippet view article find links to article

Stephen O.; Netherland, Michael; Dayan, Franck E. (2004-10-01). "Somatic mutation-mediated evolution of herbicide resistance in the nonindigenous invasive

Warburg hypothesis (732 words) [view diff] exact match in snippet view article find links to article

respiration; this observation is also known as the Warburg effect. In the somatic mutation theory of cancer, malignant proliferation is caused by mutations and

Index of topics related to life extension (806 words) [view diff] exact match in snippet view article find links to article

aging Rate of living theory Reliability theory of aging and longevity Somatic mutation theory of aging Thiel, Peter Timeline of senescence research Tissue

CHILD syndrome (882 words) [view diff] exact match in snippet view article find links to article

one having a normal 46,XY karyotype, suggesting an early postzygotic somatic mutation.[citation needed] Because CHILD syndrome is a congenital disorder,

MAPKAPK5 (756 words) [view diff] exact match in snippet view article find links to article

Barenkamp SJ, et al. (2002). "Recurrent variable region gene usage and somatic mutation in the human antibody response to the capsular polysaccharide of Streptococcus

DNA damage theory of aging (11,163 words) [view diff] exact match in snippet view article find links to article

relationship between somatic mutation rate and lifespan across different mammalian species suggests that evolution may constrain somatic mutation rates, perhaps

CSDA (gene) (840 words) [view diff] exact match in snippet view article

PMC 155318. PMID 11799066. Hayashi J, Kajino K, Umeda T, et al. (2003). "Somatic mutation and SNP in the promoter of dbpA and human hepatocarcinogenesis". Int

FLT4 (1,183 words) [view diff] exact match in snippet view article find links to article

Mizeracki A, Blei F, Walker JW, Reinisch JF, Marchuk DA (March 2002). "Somatic mutation of vascular endothelial growth factor receptors in juvenile hemangioma"

MUTYH (2,955 words) [view diff] exact match in snippet view article find links to article

adenomatous polyposis Autosomal recessive Pilomatricoma Somatic mutation Gastric cancer Somatic mutation Endometrial cancer Biallelic germline mutation

ST7 (911 words) [view diff] exact match in snippet view article find links to article

Q, Ao Y, Wang ZN, Ao X, Jiang L, Luo Y, Zhang X (December 2003). "Somatic mutation analysis of p53 and ST7 tumor suppressor genes in gastric carcinoma

Neuroblastoma RAS viral oncogene homolog (1,205 words) [view diff] exact match in snippet view article find links to article

"Activation of an N-ras gene in acute myeloblastic leukemia through somatic mutation in the first exon". Proc. Natl. Acad. Sci. U.S.A. 82 (3): 879–82. Bibcode:1985PNAS

Variant Call Format (1,061 words) [view diff] exact match in snippet view article find links to article

strand bias at this position SOMATIC indicates that the record is a somatic mutation, for cancer genomics VALIDATED validated by follow-up experiment 1000G

Deep homology (1,318 words) [view diff] case mismatch in snippet view article find links to article

C.W. (2020-06-09), "Comparison of the Atavistic Model of Cancer to Somatic Mutation Theory: Phylostratigraphic Analyses Support the Atavistic Model", The

Porokeratotic eccrine ostial and dermal duct nevus (949 words) [view diff] exact match in snippet view article find links to article

variant of keratitis ichthyosis deafness (KID) syndrome caused by a somatic mutation in GJB2, which encodes a gap junction protein called connexin-26. PEODDN

Port-wine stain (1,191 words) [view diff] case mismatch in snippet view article find links to article

(8 May 2013). "Sturge–Weber Syndrome and Port-Wine Stains Caused by Somatic Mutation in". New England Journal of Medicine. 368 (21): 1971–9. doi:10.1056/NEJMoa1213507

MINPP1 (670 words) [view diff] exact match in snippet view article find links to article

PMC 311072. PMID 11230166. Gimm O, Chi H, Dahia PL, et al. (2001). "Somatic mutation and germline variants of MINPP1, a phosphatase gene located in proximity

BEAMing (1,049 words) [view diff] exact match in snippet view article find links to article

address was the detection of minor quantities of a pre-determined somatic mutation in larger cell populations. While both digital and classical PCR can

Pando (tree) (3,970 words) [view diff] exact match in snippet view article

could be between 16,000 and 80,000 years old again based on the first somatic mutation model of the tree, but, that research has not finished peer review

Adenine phosphoribosyltransferase (2,410 words) [view diff] case mismatch in snippet view article find links to article

O'Neill P, Albertini RJ, Stambrook PJ, Sahota AS (1995). "Germline and Somatic Mutation at the APRT Locus of Mice and Man". Purine and Pyrimidine Metabolism

DNA polymerase alpha catalytic subunit (1,768 words) [view diff] exact match in snippet view article find links to article

intron 13th, other somatic mutations in POLA1 were also described. Somatic mutation are associated with more profound deficiency of POLA1, with develops

Granulosa cell tumour (1,249 words) [view diff] exact match in snippet view article find links to article

to contain an identical mutation in the FOXL2 gene [1]. This is a somatic mutation, meaning it is not usually transmitted to descendants. Mutation c.402C>G

SIAH1 (1,418 words) [view diff] exact match in snippet view article find links to article

Medhioub M, Vaury C, Hamelin R, Thomas G (September 2000). "Lack of somatic mutation in the coding sequence of SIAH1 in tumors hemizygous for this candidate

Medullary thyroid cancer (2,321 words) [view diff] exact match in snippet view article find links to article

Approximately 25-60% of sporadic medullary thyroid carcinomas have a somatic mutation (one that occurs within a single "parafollicular" cell) of the RET

PIGA (1,106 words) [view diff] exact match in snippet view article find links to article

Kinoshita T (Jun 1993). "Deficiency of the GPI anchor caused by a somatic mutation of the PIG-A gene in paroxysmal nocturnal hemoglobinuria". Cell. 73

Zond 5 (2,357 words) [view diff] case mismatch in snippet view article find links to article

radiation sickness 6 May 2002 www.upi.com accessed 21 September 2021 SOMATIC MUTATION RATE IN TRADESCANTIA STAMEN HAIRS AT LOW RADIATION LEVELS: FINDING

Signet ring cell carcinoma (2,270 words) [view diff] exact match in snippet view article find links to article

Ichii S, Tahara E, Kato Y, Nakamura Y, Horii A (November 1992). "Somatic mutation of the APC gene in gastric cancer: frequent mutations in very well

N-Myc (1,978 words) [view diff] exact match in snippet view article find links to article

MYCN can also be activated in neuroblastoma and other cancers through somatic mutation. Intriguingly, recent genome-wide H3K27ac profiling in patient-derived

James E. Bowman (1,356 words) [view diff] case mismatch in snippet view article find links to article

"Hemoglobin and the genetic code: Evolution of Protection against Somatic Mutation". Journal of Molecular Evolution. 9 (3). Springer New York: 225–230

RNF20 (865 words) [view diff] exact match in snippet view article find links to article

IS, Alizadeh AA, Eisen MB, et al. (2000). "Ongoing immunoglobulin somatic mutation in germinal center B cell-like but not in activated B cell-like diffuse

MYD88 (2,250 words) [view diff] exact match in snippet view article find links to article

Yang G, Zhou Y, Liu X, Cao Y, et al. (August 2012). "MYD88 L265P somatic mutation in Waldenström's macroglobulinemia". The New England Journal of Medicine

Follicular dendritic cells (1,896 words) [view diff] exact match in snippet view article find links to article

centers (GCs), where antigen-activated B cells are trapped to undergo somatic mutation, positive and negative selection, isotype switching, and differentiation

Aristolochia (3,052 words) [view diff] exact match in snippet view article find links to article

with a known exposure to aristolochic acid revealed a higher rate of somatic mutation in DNA. Metabolites of aristolochic acid enter the cell nucleus and

STK11 (2,791 words) [view diff] exact match in snippet view article find links to article

Straten P, Ahrenkiel V, Seremet T, Kirkin AF, Zeuthen J (March 1999). "Somatic mutation of the Peutz-Jeghers syndrome gene, LKB1/STK11, in malignant melanoma"

ADAMTS7 (1,262 words) [view diff] exact match in snippet view article find links to article

Christine B.; Wang, Jianmin; Liu, Song (2016-05-26). "Differences in somatic mutation landscape of hepatocellular carcinoma in Asian American and European

Multiple endocrine neoplasia (2,229 words) [view diff] exact match in snippet view article find links to article

cases) and present in all cells at birth. The second hit is a MEN1 somatic mutation, usually a large deletion, that occurs in the predisposed endocrine

Stephen Chanock (931 words) [view diff] exact match in snippet view article find links to article

evidence that cancer susceptibility regions are preferential targets for somatic mutation". Genome Biology. 16 (1): 193. doi:10.1186/s13059-015-0755-5. ISSN 1474-7596

Parasitic plant (3,376 words) [view diff] exact match in snippet view article find links to article

neighbouring trees, usually the parent tree from which they have grown (via a somatic mutation). Parasitic plants germinate in several methods. These can either be

Bob Löwenberg (994 words) [view diff] exact match in snippet view article find links to article

cells. He and his colleagues discovered for the first time an acquired somatic mutation in a hematopoietic growth factor receptor gene (G-CSF-R) in a human

Li Ding (337 words) [view diff] exact match in snippet view article find links to article

that play a role in cancer. Koboldt, DC, et al. (2012). "VarScan 2: somatic mutation and copy number alteration discovery in cancer by exome sequencing"

SMUG1 (2,233 words) [view diff] exact match in snippet view article find links to article

complementary paths to both Ig switching and the A/T-focused phase of somatic mutation". Molecular Cell. 16 (2): 163–71. doi:10.1016/j.molcel.2004.10.011

RARA Gene (527 words) [view diff] exact match in snippet view article find links to article

is a condition known as Acute Promyeloid Leukemia (APL) caused by a somatic mutation described by the fusion of RARA and the PML gene located on chromosome

Genome (4,913 words) [view diff] exact match in snippet view article find links to article

PMC 1681520. PMID 16924266. Martincorena I, Campbell PJ (September 2015). "Somatic mutation in cancer and normal cells". Science. 349 (6255): 1483–89. Bibcode:2015Sci

Small intestine neuroendocrine tumor (949 words) [view diff] exact match in snippet view article find links to article

Banck, Michaela S.; Kanwar, Rahul; Kulkarni, Amit A. (December 2013). "Somatic mutation of CDKN1B in small intestine neuroendocrine tumors". Nature Genetics

Katherine MacLean (2,220 words) [view diff] exact match in snippet view article find links to article

also, and produces cancer. This cannot be prevented. She called it "somatic mutation" and used the new concept of body deterioration by slow radiation damage

Postzygotic mutation (1,634 words) [view diff] exact match in snippet view article find links to article

2174/138920210793176056. ISSN 1389-2029. PMC 3018721. PMID 21358985. "Somatic mutation – Glossary Entry". Genetics Home Reference. 2015-11-09. Retrieved 2015-11-14

J. Donald Capra (1,720 words) [view diff] exact match in snippet view article find links to article

Bouteiller, O.; Banchereau, J.; Capra, J. D. (1994). "Analysis of somatic mutation in five B cell subsets of human tonsil". The Journal of Experimental

Aneuploidy (3,586 words) [view diff] exact match in snippet view article find links to article

PMID 19424483. Duesberg, P.; Rasnick, D. (2000). "Aneuploidy, the somatic mutation that makes cancer a species of its own". Cell Motility and the Cytoskeleton

P110α (1,929 words) [view diff] exact match in snippet view article find links to article

Earl HM, Pharoah PD, Ross MT, Aparicio S, Caldas C (May 2016). "The somatic mutation profiles of 2,433 breast cancers refines their genomic and transcriptomic

Neuropilin 1 (1,812 words) [view diff] exact match in snippet view article find links to article

PE, Waner M, Mizeracki A, Blei F, Walker JW, et al. (March 2002). "Somatic mutation of vascular endothelial growth factor receptors in juvenile hemangioma"

Sturge–Weber syndrome (1,650 words) [view diff] case mismatch in snippet view article find links to article

(8 May 2013). "Sturge–Weber Syndrome and Port-Wine Stains Caused by Somatic Mutation in". New England Journal of Medicine. 368 (21): 1971–9. doi:10.1056/NEJMoa1213507

Pig-a gene mutation assay (568 words) [view diff] exact match in snippet view article find links to article

Originally, PIG-A assay was proposed as a method for monitoring humans for somatic mutation. The assay was developed as an extension of flow cytometric procedure

Tradescantia (2,620 words) [view diff] case mismatch in snippet view article find links to article

ISSN 1424-8581. PMID 21709415. S2CID 39983260. Ichikawa, Sadao (1972). "Somatic Mutation Rate in Tradescantia Stamen Hairs at Low Radiation Levels: Finding

Anne Comi (260 words) [view diff] exact match in snippet view article find links to article

School of Medicine. In 2013, Comi and her research team identified a somatic mutation on the GNAQ gene as the cause of Sturge-Weber Syndrome, a discovery

FAT1 (2,060 words) [view diff] exact match in snippet view article find links to article

Ramaswami D, Walsh LA, Turcan Ş, et al. (March 2013). "Recurrent somatic mutation of FAT1 in multiple human cancers leads to aberrant Wnt activation"

Metastasis (5,069 words) [view diff] exact match in snippet view article find links to article

likely not sample from the subpopulation with metastatic potential. The somatic mutation theory of metastasis development has not been substantiated in human

Yoshitaka Nishimura (1,354 words) [view diff] exact match in snippet view article find links to article

Again -DJ Yoshitaka Remix- Max Love (with Kanako Hoshino) Anisakis -somatic mutation type"Forza"- (under another alias, 朱雀 [Suzaku]) Mendes (under another

Gary Firestein (1,188 words) [view diff] exact match in snippet view article find links to article

evaluate drug mechanism of action in arthritis and demonstrated that somatic mutation could increase joint damage in rheumatoid arthritis. More recently

Ollier disease (3,564 words) [view diff] exact match in snippet view article find links to article

disease would suggest that the condition is caused by a post-zygotic somatic mutation thus resulting in a mosaic genetic disorder. Approximately 8–10% of

Langerhans cell histiocytosis (4,022 words) [view diff] exact match in snippet view article find links to article

to demonstrate convincingly that LCH is a malignancy. An activating somatic mutation of a proto-oncogene in the Raf family, the BRAF gene, was detected

Gaylussacia brachycera (2,281 words) [view diff] exact match in snippet view article find links to article

taken from the colony, but they are thought to have arisen through somatic mutation rather than sexual reproduction. Unfortunately, the destruction of

A. Thomas Look (1,392 words) [view diff] exact match in snippet view article find links to article

Thomas (12 December 2014). "An oncogenic super-enhancer formed through somatic mutation of a noncoding intergenic element". Science. 346 (6215): 1373–1377

Norrie disease (3,739 words) [view diff] exact match in snippet view article find links to article

could be the case in consanguineous families or due to a spontaneous somatic mutation. Another explanation for affected females could be skewed X-chromosome

MSH3 (2,080 words) [view diff] exact match in snippet view article find links to article

instabilities (MSI) in the genome and allowing an increase in the rates of somatic mutation. Elevated microsatellite alterations at selected tetranucleotide repeats

Pinot noir (5,744 words) [view diff] exact match in snippet view article find links to article

mutation of Pinot noir or Pinot blanc), presumably representing a somatic mutation in either the VvMYBA1 or VvMYBA2 genes that control grape berry color

History of cancer chemotherapy (3,847 words) [view diff] exact match in snippet view article find links to article

particular cancer, such a network may be radically altered, due to a chance somatic mutation. Targeted therapy inhibits the metabolic pathway that underlies that

Mutagen (5,997 words) [view diff] exact match in snippet view article find links to article

November 2023. Duesberg P, Rasnick D (October 2000). "Aneuploidy, the somatic mutation that makes cancer a species of its own". Cell Motility and the Cytoskeleton

MBD4 (2,301 words) [view diff] exact match in snippet view article find links to article

Zhu B, Rausch T, et al. (Nov 2017). "Germline determinants of the somatic mutation landscape in 2,642 cancer genomes". bioRxiv 10.1101/208330. Rodrigues

Isogenic human disease models (2,046 words) [view diff] exact match in snippet view article find links to article

Sartore-Bianchi A, Benvenuti S, Artale S, Bardelli A, Siena S (November 2005). "Somatic mutation of EGFR catalytic domain and treatment with gefitinib in colorectal

Frameshift mutation (4,728 words) [view diff] exact match in snippet view article find links to article

diagnosis of diseases caused by or associated with a gene having a somatic mutation giving rise to a frameshift mutation. The methods include providing

Epilepsy (18,627 words) [view diff] exact match in snippet view article find links to article

is often pursued. Sturge-Weber syndrome is caused by an activating somatic mutation in the GNAQ gene and it affects approximately 1 in 20,000–50,000 live

DNA repair (16,024 words) [view diff] exact match in snippet view article find links to article

Deficiencies in DNA repair enzymes are occasionally caused by a newly arising somatic mutation in a DNA repair gene, but are much more frequently caused by epigenetic

Stem cell theory of aging (2,594 words) [view diff] exact match in snippet view article find links to article

regulation (gene expression), codon restriction, error catastrophe, somatic mutation, accumulation of genetic material (DNA) damage (DNA damage theory of

Recombinant AAV mediated genome engineering (2,673 words) [view diff] exact match in snippet view article find links to article

Sartore-Bianchi A, Benvenuti S, Artale S, Bardelli A, Siena S (November 2005). "Somatic mutation of EGFR catalytic domain and treatment with gefitinib in colorectal

BioSamples (1,408 words) [view diff] case mismatch in snippet view article find links to article

The Cancer Genome Atlas, and 920,441 samples from the Catalogue of Somatic Mutation in Cancer (COSMIC). Attributes define the material under investigation

Adoptive cell transfer (3,797 words) [view diff] exact match in snippet view article find links to article

HPV antigens 2014 Bile duct Mutated ERB2 1 – Selected to target a somatic mutation In vitro sensitization 2008 Melanoma NY-ESO-1 9 33% Clones reactive

Senescence (7,177 words) [view diff] exact match in snippet view article find links to article

regulation (gene expression), codon restriction, error catastrophe, somatic mutation, accumulation of genetic material (DNA) damage (DNA damage theory of

Chromosome conformation capture (5,404 words) [view diff] exact match in snippet view article find links to article

"Oncogene regulation. An oncogenic super-enhancer formed through somatic mutation of a noncoding intergenic element". Science. 346 (6215): 1373–7. doi:10

Elora López-Nandam (971 words) [view diff] exact match in snippet view article find links to article

Albright R, Palumbi SR. Genome integrity and the heritability of somatic mutation in clonal, colonial corals. Poster presentation online for The Allied

Diane Barber (2,348 words) [view diff] exact match in snippet view article find links to article

pHi on the glycolytic enzymes necessary for metabolic programming, somatic mutation biology, and tumorigenic behaviors. The research uses optogenetic tools

Cancer genome sequencing (3,085 words) [view diff] exact match in snippet view article find links to article

approximately 65-fold coverage. To facilitate further improvement in somatic mutation detection in cancer, the Sequencing Quality Control Phase 2 Consortium

Labrador Retriever coat colour genetics (3,101 words) [view diff] exact match in snippet view article find links to article

Labrador with black pigment. The most probable cause was either a somatic mutation early in development or a fusion between two zygotes that left some

HRDetect (1,809 words) [view diff] exact match in snippet view article find links to article

deficiency with germline BRCA1/2 mutations, 22 patients displayed somatic mutation of BRCA1/2, and 47 were recognized to show functional defect without

Timeline of tuberous sclerosis (5,396 words) [view diff] exact match in snippet view article find links to article

congenital germline mutation which was combined with an early lifetime somatic mutation to cause a tumour. This model applies to many conditions involving

Autosomal dominant polycystic kidney disease (6,338 words) [view diff] exact match in snippet view article find links to article

Gandolph MA, Qian F, Onuchic LF, Klinger KW, et al. (August 1998). "Somatic mutation in individual liver cysts supports a two-hit model of cystogenesis

Cancer systems biology (3,591 words) [view diff] exact match in snippet view article find links to article

Wooster, R; Futreal, PA; Stratton, MR (8 March 2007). "Patterns of somatic mutation in human cancer genomes". Nature. 446 (7132): 153–8. Bibcode:2007Natur

Oncogenomics (7,684 words) [view diff] exact match in snippet view article find links to article

Rogozin IB, Pavlov YI, Bebenek K, Matsuda T, Kunkel TA (June 2001). "Somatic mutation hotspots correlate with DNA polymerase eta error spectrum". Nat. Immunol

ADAR (4,802 words) [view diff] exact match in snippet view article find links to article

erythrocyte differentiation somatic diversification of immune receptors via somatic mutation definitive hemopoiesis positive regulation of viral genome replication

Pathway analysis (2,906 words) [view diff] exact match in snippet view article find links to article

Pramana S, Saputra D, Joshi H, et al. (August 2015). "Integration of somatic mutation, expression and functional data reveals potential driver genes predictive

Royal Medal (4,182 words) [view diff] exact match in snippet view article find links to article

signatures, which have transformed our understanding of cancer and somatic mutation." Ravinder Maini Marc Feldmann Medicine "for inventing anti-TNF therapy

Mutational signatures (4,037 words) [view diff] case mismatch in snippet view article find links to article

Signatures of Mutational Processes in Human Cancer from the Catalogue of Somatic Mutation In Cancer (COSMIC) database. De novo mutational signatures modelling

Ovarian cancer (21,252 words) [view diff] exact match in snippet view article find links to article

hypercalcemia. Recent research has found an inactivating germline and somatic mutation of SMARCA4 gene. The hypercalcemic subtype is very aggressive and has

Tumour heterogeneity (7,134 words) [view diff] exact match in snippet view article find links to article

C. A.; Mardis, E. R.; Ding, L; Wilson, R. K. (2012). "Var Scan 2: Somatic mutation and copy number alteration discovery in cancer by exome sequencing"

The Cancer Genome Atlas (7,468 words) [view diff] exact match in snippet view article find links to article

admixture, pseudohypoxia and kinase signaling; MAML3 fusion gene and CSDE1 somatic mutation define and drive the poor prognosis, Wnt-altered subtype Cholangiocarcinoma

Somatic evolution in cancer (9,928 words) [view diff] exact match in snippet view article find links to article

mutations; one of which could be inherited or somatic followed by a second somatic mutation. Cytogenetic studies localized the region to the long arm of chromosome

Trinucleotide repeat expansion (7,967 words) [view diff] exact match in snippet view article find links to article

(2007-06-01). "Inherited CAG.CTG allele length is a major modifier of somatic mutation length variability in Huntington disease". DNA Repair. 6 (6): 789–796

Folliculin (5,618 words) [view diff] exact match in snippet view article find links to article

remaining wild type copy is inactivated in the tumor cells through somatic mutation or loss of heterozygosity. Naturally-occurring dog and rat models with

Tumor antigens recognized by T lymphocytes (2,942 words) [view diff] exact match in snippet view article find links to article

named: T cell immunosurveillance of the integrity of the genome. Any somatic mutation has a probability of producing a new antigen that can be recognized

RBM10 (5,530 words) [view diff] exact match in snippet view article find links to article

Janakiraman V, Bhatt D, Stern HM, et al. (August 2010). "Diverse somatic mutation patterns and pathway alterations in human cancers". Nature. 466 (7308):

GESTALT (2,706 words) [view diff] exact match in snippet view article find links to article

Lee, Eunjung; Park, Peter J.; Walsh, Christopher A. (2015-10-02). "Somatic mutation in single human neurons tracks developmental and transcriptional history"

Viticulture in Paraná (2,596 words) [view diff] exact match in snippet view article find links to article

Mr. Hashima, an agricultural engineer, soon verified that it was a somatic mutation. At the same time, Okuyama observed almost daily what was happening

Super-enhancer (6,636 words) [view diff] exact match in snippet view article find links to article

"Oncogene regulation. An oncogenic super-enhancer formed through somatic mutation of a noncoding intergenic element". Science. 346 (6215): 1373–7. doi:10

Neurogenomics (9,520 words) [view diff] exact match in snippet view article find links to article

Soohyun; Chittenden, Thomas W.; D'Gama, Alissa M. (2015-10-02). "Somatic mutation in single human neurons tracks developmental and transcriptional history"

List of sequenced plant genomes (10,407 words) [view diff] exact match in snippet view article find links to article

Quercus robur (European oak) Fagaceae Pedunculate oak, large diversity, somatic mutation studies 736 Mb 25,808 12 Biogeco lab, Inrae, University of Bordeaux