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searching for P110α 5 found (16 total)

alternate case: p110α

Taselisib (178 words) [view diff] exact match in snippet view article find links to article

molecule phosphoinositide 3-kinase inhibitor targeting the PI3K isoform p110α (PIK3CA). Roche announced in June 2018 that there would be no further development

Alpelisib (1,129 words) [view diff] exact match in snippet view article find links to article

Merry, T. L. (2023). Dietary supplementation of clinically utilized PI3K p110α inhibitor extends the lifespan of male and female mice. Nature Aging, 3

ErbB (2,736 words) [view diff] exact match in snippet view article find links to article

relation to breast tumors, somatic activating mutations in Akt and the p110α subunit of the PI3K have been detected in 3–5% and 20–25% of primary breast

MTOR inhibitors (6,225 words) [view diff] exact match in snippet view article find links to article

of dual mTOR/PI3K inhibitors. These inhibitors target isoforms of PI3K (p110α, β and γ) along with ATP-binding sites of mTORC1 and mTORC2 by blocking

O-GlcNAc (12,376 words) [view diff] exact match in snippet view article find links to article

signaling pathway, including β-catenin, IR-β, IRS1, Akt, PDK1, and the p110α subunit of PI3K were found to be directly modified by O-GlcNAc. Insulin