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Longer titles found: Granzyme A (view), Granzyme B (view)

searching for Granzyme 45 found (97 total)

alternate case: granzyme

GZMH (695 words) [view diff] exact match in snippet view article find links to article

Granzyme H is a protein that in humans is encoded by the GZMH gene. GRCh38: Ensembl release 89: ENSG00000100450 - Ensembl, May 2017 GRCm38: Ensembl release
SERPINB9 (1,041 words) [view diff] exact match in snippet view article find links to article
"Perforin-independent expression of granzyme B and proteinase inhibitor 9 in human testis and placenta suggests a role for granzyme B-mediated proteolysis in reproduction"
GZMM (533 words) [view diff] exact match in snippet view article find links to article
collectively termed granzymes and include 4 distinct gene products: granzyme A, granzyme B, granzyme H, and Met-ase, also known as granzyme M. GRCh38: Ensembl
GZMK (675 words) [view diff] exact match in snippet view article find links to article
Granzyme K is a protein that in humans is encoded by the GZMK gene. This gene product is a member of a group of related serine proteases from the cytoplasmic
Heparan sulfate (3,653 words) [view diff] exact match in snippet view article find links to article
angiogenesis, blood coagulation, abolishing detachment activity by GrB (Granzyme B), and tumour metastasis. HS has also been shown to serve as cellular
Protein SET (1,267 words) [view diff] exact match in snippet view article find links to article
assembly protein SET and is a target of the cytotoxic T-lymphocyte protease granzyme A". Molecular and Cellular Biology. 22 (8): 2810–20. doi:10.1128/mcb.22
HMGB2 (1,189 words) [view diff] exact match in snippet view article find links to article
assembly protein SET and is a target of the cytotoxic T-lymphocyte protease granzyme A". Molecular and Cellular Biology. 22 (8): 2810–20. doi:10.1128/MCB.22
ELISpot (1,980 words) [view diff] exact match in snippet view article find links to article
cytokine responses, antibody specific secreting cells, tumor antigens, granzyme B and Perforin release by T cells, vaccine efficacy, epitope mapping, cytotoxic
XCL1 (1,204 words) [view diff] exact match in snippet view article find links to article
GO:0032854 positive regulation of GTPase activity positive regulation of granzyme A production positive regulation of immunoglobulin production in mucosal
TREX1 (1,263 words) [view diff] exact match in snippet view article find links to article
SET complex, and acts to rapidly degrade 3' ends of nicked DNA during granzyme A-mediated cell death. Mutations in this gene result in Aicardi-Goutieres
Nucleolin (1,929 words) [view diff] exact match in snippet view article find links to article
Pasternack MS, Bleier KJ, McInerney TN (Aug 1991). "Granzyme A binding to target cell proteins. Granzyme A binds to and cleaves nucleolin in vitro". The Journal
Acidic leucine-rich nuclear phosphoprotein 32 family member A (990 words) [view diff] exact match in snippet view article find links to article
assembly protein SET and is a target of the cytotoxic T-lymphocyte protease granzyme A". Mol. Cell. Biol. 22 (8): 2810–20. doi:10.1128/MCB.22.8.2810-2820.2002
UBE4B (818 words) [view diff] exact match in snippet view article find links to article
the yeast polyubiquitination factor Ufd2p is cleaved by caspase 6 and granzyme B during apoptosis". Biochem. J. 361 (Pt 3): 587–95. doi:10.1042/0264-6021:3610587
Caspase-9 (4,319 words) [view diff] exact match in snippet view article find links to article
the ICE/Ced-3 gene family, is activated by the cytotoxic T cell protease granzyme B". The Journal of Biological Chemistry. 271 (28): 16720–4. doi:10.1074/jbc
LILRA4 (522 words) [view diff] exact match in snippet view article find links to article
hybridization reveals the expression of immunoglobulin-like transcript 7, Eph-B1, granzyme B, and 3 novel transcripts in human plasmacytoid dendritic cells". Blood
Interleukin 28 (721 words) [view diff] exact match in snippet view article find links to article
Lewis MG, Talbott K, et al. (September 2010). "IL-28B/IFN-lambda 3 drives granzyme B loading and significantly increases CTL killing activity in macaques"
CD244 (1,130 words) [view diff] exact match in snippet view article find links to article
membrane Biological process innate immune response positive regulation of granzyme B production immune system process leukocyte migration adaptive immune
Cathepsin C (1,847 words) [view diff] exact match in snippet view article find links to article
with Papillon-Lefevre syndrome reveals a requirement for cathepsin C in granzyme B activation and NK cell cytolytic activity". Blood. 107 (9): 3665–8. doi:10
ANP32C (457 words) [view diff] exact match in snippet view article find links to article
"Cleaving the oxidative repair protein Ape1 enhances cell death mediated by granzyme A". Nature Immunology. 4 (2): 145–53. doi:10.1038/ni885. PMID 12524539
Type 1 regulatory T cell (1,869 words) [view diff] exact match in snippet view article find links to article
production in vitro. Cytolitic activity: Tr1 cells can both express Granzyme A and granzyme B. It was shown recently, that Tr1 cells, in vitro and also ex
GRIA3 (2,070 words) [view diff] exact match in snippet view article find links to article
PMC 1369911. PMID 10688364. Gahring L, Carlson NG, Meyer EL, Rogers SW (2001). "Granzyme B proteolysis of a neuronal glutamate receptor generates an autoantigen
LAMP1 (2,160 words) [view diff] exact match in snippet view article find links to article
organelle positive regulation of natural killer cell mediated cytotoxicity granzyme-mediated apoptotic signaling pathway autophagic cell death neutrophil degranulation
Eomesodermin (2,014 words) [view diff] exact match in snippet view article find links to article
expression of effector molecules (eomesodermin and its targets: perforin and granzyme B)". Journal of Immunology. 180 (12): 8102–8. doi:10.4049/jimmunol.180
UBE4A (547 words) [view diff] exact match in snippet view article find links to article
the yeast polyubiquitination factor Ufd2p is cleaved by caspase 6 and granzyme B during apoptosis". Biochem. J. 361 (Pt 3): 587–95. doi:10.1042/0264-6021:3610587
Nuclear mitotic apparatus protein 1 (1,104 words) [view diff] exact match in snippet view article find links to article
PMID 9288109. S2CID 21975861. Andrade F, Roy S, Nicholson D, et al. (1998). "Granzyme B directly and efficiently cleaves several downstream caspase substrates:
CMA1 (889 words) [view diff] exact match in snippet view article find links to article
"The human mast cell chymase gene (CMA1): mapping to the cathepsin G/granzyme gene cluster and lineage-restricted expression". Genomics. 15 (3): 614–20
Memory T cell (2,707 words) [view diff] exact match in snippet view article find links to article
present. One mechanism used by TRM to restrict pathogens is the secretion of granzyme B. TSCM: Those lymphocytes are capable of self-renewal as are the TCM lymphocytes
Toxic epidermal necrolysis (2,575 words) [view diff] exact match in snippet view article find links to article
cell death through release of a number of molecules, including perforin, granzyme B, and granulysin. Other agents, including tumor necrosis factor alpha
PD-L1 (2,610 words) [view diff] exact match in snippet view article find links to article
Blockade reduced TNFα and nitric oxide production by macrophages, reduced granzyme B production by NK cells, and decreased proliferation of L. monocytogenes
Fucosyltransferase 4 (537 words) [view diff] exact match in snippet view article find links to article
expression of Lewis X and Y antigens on the cell surface and FUT 4 mRNA during granzyme B-induced Jurkat cell apoptosis". Biol. Pharm. Bull. 30 (4): 655–60. doi:10
Signaling lymphocytic activation molecule (1,120 words) [view diff] exact match in snippet view article find links to article
of multiple myeloma patients. Elotuzumab stimulates NK cells to release granzyme through blocking SLAMF7, through triggering antibody-dependent cellular
Peter Openshaw (immunologist) (885 words) [view diff] exact match in snippet view article
J.; Johansson, C.; Openshaw, P. (2012). "Regulatory T cells expressing granzyme B play a critical role in controlling lung inflammation during acute viral
Nancy Thornberry (1,487 words) [view diff] exact match in snippet view article find links to article
Combinatorial Approach Defines Specificities of Members of the Caspase Family and Granzyme B". Journal of Biological Chemistry. 272 (29): 17907–17911. doi:10.1074/jbc
DFFA (1,403 words) [view diff] exact match in snippet view article find links to article
(June 2001). "Direct cleavage of the human DNA fragmentation factor-45 by granzyme B induces caspase-activated DNase release and DNA fragmentation". The EMBO
NDUFS3 (2,063 words) [view diff] exact match in snippet view article find links to article
ajhg.2009.04.020. PMC 2694978. PMID 19463981. Lieberman J (May 2010). "Granzyme A activates another way to die". Immunological Reviews. 235 (1): 93–104
Interleukin 10 (4,696 words) [view diff] exact match in snippet view article find links to article
been shown to enhance CD8+ T cell secretion of the cytotoxic molecules Granzyme B and Perforin and potentiate T cell receptor dependent IFNγ secretion
Living medicine (896 words) [view diff] exact match in snippet view article find links to article
subunit of the bacterial flagellum) via TLR5 activation. The perforin and granzyme proteins secreted by activated CD8+ T cells efficiently kill tumor cells
Glypican 3 (2,593 words) [view diff] exact match in snippet view article find links to article
cells can eliminate GPC3-positive cancer cells, by inducing perforin- and granzyme-mediated cell death and reducing Wnt signaling in tumor cells. CAR (hYP7)
Lichen planus (6,168 words) [view diff] exact match in snippet view article find links to article
mechanisms such as secretion of tumor necrosis factor (TNF)-alpha, secretion of granzyme B, or Fas-Fas ligand interactions. Chemokines are produced by activated
Bacterial therapy (871 words) [view diff] exact match in snippet view article find links to article
subunit of the bacterial flagellum) via TLR5 activation. The perforin and granzyme proteins secreted by activated CD8+ T cells efficiently kill tumor cells
Caspase-activated DNase (3,073 words) [view diff] exact match in snippet view article find links to article
(June 2001). "Direct cleavage of the human DNA fragmentation factor-45 by granzyme B induces caspase-activated DNase release and DNA fragmentation". The EMBO
Veto cells (2,142 words) [view diff] exact match in snippet view article find links to article
cognate CD8 T cells by immature dendritic cells: a novel role for perforin, granzyme A, TREM-1, and TLR7". Blood. 120 (8): 1647–57. doi:10.1182/blood-2012-02-410803
BNIP3 (2,667 words) [view diff] exact match in snippet view article find links to article
process GO:0022415 viral process negative regulation of mitochondrial fusion granzyme-mediated apoptotic signaling pathway mitochondrial outer membrane permeabilization
Aviptadil (2,781 words) [view diff] exact match in snippet view article find links to article
VIP is a proven inhibitor of activation-induced perforin, as well as of granzyme B and therefore actively contributes to the reduction of deleterious proinflammatory
2014 in science (25,108 words) [view diff] exact match in snippet view article find links to article
Intelligence" (AI100). By blocking the activity of an enzyme known as Granzyme b, researchers have slowed aging in the skin of mice. 17 December – A Colorado