Find link

language:

Find link is a tool written by Edward Betts.

Longer titles found: Granzyme A (view), Granzyme B (view)

searching for Granzyme 46 found (113 total)

alternate case: granzyme

GZMM (543 words) [view diff] exact match in snippet view article find links to article

collectively termed granzymes and include 4 distinct gene products: granzyme A, granzyme B, granzyme H, and Met-ase, also known as granzyme M. GRCh38: Ensembl

SERPINB9 (1,121 words) [view diff] exact match in snippet view article find links to article

in humans is encoded by the SERPINB9 gene. Serpin B9 is an inhibitor of Granzyme B (GzmB). GzmB is a potent cytotoxic molecule that is secreted by cytotoxic

GZMH (698 words) [view diff] exact match in snippet view article find links to article

Granzyme H is a protein that in humans is encoded by the GZMH gene. GRCh38: Ensembl release 89: ENSG00000100450 – Ensembl, May 2017 GRCm38: Ensembl release

Protein SET (1,281 words) [view diff] exact match in snippet view article find links to article

assembly protein SET and is a target of the cytotoxic T-lymphocyte protease granzyme A". Molecular and Cellular Biology. 22 (8): 2810–20. doi:10.1128/mcb.22

HMGB2 (1,194 words) [view diff] exact match in snippet view article find links to article

assembly protein SET and is a target of the cytotoxic T-lymphocyte protease granzyme A". Molecular and Cellular Biology. 22 (8): 2810–20. doi:10.1128/MCB.22

Lymphomatoid papulosis (352 words) [view diff] exact match in snippet view article find links to article

and CD30+ lymphocytes that often stain with cytotoxic markers (TIA-1, granzyme, perforin). E Angioinvasive with small to large angiocentric CD30+ atypical

XCL1 (1,221 words) [view diff] exact match in snippet view article find links to article

chemotaxis positive regulation of GTPase activity positive regulation of granzyme A production positive regulation of immunoglobulin production in mucosal

LILRA4 (548 words) [view diff] exact match in snippet view article find links to article

hybridization reveals the expression of immunoglobulin-like transcript 7, Eph-B1, granzyme B, and 3 novel transcripts in human plasmacytoid dendritic cells". Blood

Acidic leucine-rich nuclear phosphoprotein 32 family member A (1,011 words) [view diff] exact match in snippet view article find links to article

assembly protein SET and is a target of the cytotoxic T-lymphocyte protease granzyme A". Mol. Cell. Biol. 22 (8): 2810–20. doi:10.1128/MCB.22.8.2810-2820.2002

TREX1 (1,425 words) [view diff] exact match in snippet view article find links to article

SET complex, and acts to rapidly degrade 3' ends of nicked DNA during granzyme A-mediated cell death. Mutations in this gene result in Aicardi-Goutieres

TGFBR3 (1,632 words) [view diff] exact match in snippet view article find links to article

due to the proteolytic activity of the pro-apoptotic serine protease - granzyme B. Plasmin - a serine protease present in the blood, activated as part

UBE4B (825 words) [view diff] exact match in snippet view article find links to article

the yeast polyubiquitination factor Ufd2p is cleaved by caspase 6 and granzyme B during apoptosis". Biochem. J. 361 (Pt 3): 587–95. doi:10.1042/0264-6021:3610587

Nucleolin (1,936 words) [view diff] exact match in snippet view article find links to article

Pasternack MS, Bleier KJ, McInerney TN (Aug 1991). "Granzyme A binding to target cell proteins. Granzyme A binds to and cleaves nucleolin in vitro". The Journal

Caspase-9 (4,327 words) [view diff] exact match in snippet view article find links to article

the ICE/Ced-3 gene family, is activated by the cytotoxic T cell protease granzyme B". The Journal of Biological Chemistry. 271 (28): 16720–4. doi:10.1074/jbc

Interleukin 28 (721 words) [view diff] exact match in snippet view article find links to article

Lewis MG, Talbott K, et al. (September 2010). "IL-28B/IFN-lambda 3 drives granzyme B loading and significantly increases CTL killing activity in macaques"

Type 1 regulatory T cell (1,883 words) [view diff] exact match in snippet view article find links to article

production in vitro. Cytolitic activity: Tr1 cells can both express Granzyme A and granzyme B. It was shown recently, that Tr1 cells, in vitro and also ex

ANP32C (449 words) [view diff] exact match in snippet view article find links to article

"Cleaving the oxidative repair protein Ape1 enhances cell death mediated by granzyme A". Nature Immunology. 4 (2): 145–53. doi:10.1038/ni885. PMID 12524539

Eomesodermin (1,817 words) [view diff] exact match in snippet view article find links to article

expression of effector molecules (eomesodermin and its targets: perforin and granzyme B)". Journal of Immunology. 180 (12): 8102–8108. doi:10.4049/jimmunol.180

Cathepsin C (1,853 words) [view diff] exact match in snippet view article find links to article

with Papillon-Lefevre syndrome reveals a requirement for cathepsin C in granzyme B activation and NK cell cytolytic activity". Blood. 107 (9): 3665–8. doi:10

CD244 (1,909 words) [view diff] exact match in snippet view article find links to article

membrane Biological process innate immune response positive regulation of granzyme B production immune system process leukocyte migration adaptive immune

GRIA3 (2,077 words) [view diff] exact match in snippet view article find links to article

PMC 1369911. PMID 10688364. Gahring L, Carlson NG, Meyer EL, Rogers SW (2001). "Granzyme B proteolysis of a neuronal glutamate receptor generates an autoantigen

Programmed cell death (6,843 words) [view diff] exact match in snippet view article find links to article

T-cell can attach itself to a membrane, facilitating the release of granzyme B. Granzyme B perforates the target cell membrane and in turn allows the release

UBE4A (550 words) [view diff] exact match in snippet view article find links to article

the yeast polyubiquitination factor Ufd2p is cleaved by caspase 6 and granzyme B during apoptosis". Biochem. J. 361 (Pt 3): 587–95. doi:10.1042/0264-6021:3610587

Toxic epidermal necrolysis (2,603 words) [view diff] exact match in snippet view article find links to article

cell death through release of a number of molecules, including perforin, granzyme B, and granulysin. Other agents, including tumor necrosis factor alpha

LAMP1 (2,131 words) [view diff] exact match in snippet view article find links to article

organelle positive regulation of natural killer cell mediated cytotoxicity granzyme-mediated apoptotic signaling pathway autophagic cell death neutrophil degranulation

Nuclear mitotic apparatus protein 1 (1,140 words) [view diff] exact match in snippet view article find links to article

Roy S, Nicholson D, Thornberry N, Rosen A, Casciola-Rosen L (1998). "Granzyme B directly and efficiently cleaves several downstream caspase substrates:

NDUFS3 (1,704 words) [view diff] exact match in snippet view article find links to article

ajhg.2009.04.020. PMC 2694978. PMID 19463981. Lieberman J (May 2010). "Granzyme A activates another way to die". Immunological Reviews. 235 (1): 93–104

Memory T cell (3,781 words) [view diff] exact match in snippet view article find links to article

present. One mechanism used by TRM to restrict pathogens is the secretion of granzyme B. Stem cell-like memory T cells (TSCM): Those lymphocytes are capable

CMA1 (939 words) [view diff] exact match in snippet view article find links to article

"The human mast cell chymase gene (CMA1): mapping to the cathepsin G/granzyme gene cluster and lineage-restricted expression". Genomics. 15 (3): 614–20

Signaling lymphocytic activation molecule (1,117 words) [view diff] exact match in snippet view article find links to article

of multiple myeloma patients. Elotuzumab stimulates NK cells to release granzyme through blocking SLAMF7, through triggering antibody-dependent cellular

Fucosyltransferase 4 (537 words) [view diff] exact match in snippet view article find links to article

expression of Lewis X and Y antigens on the cell surface and FUT 4 mRNA during granzyme B-induced Jurkat cell apoptosis". Biol. Pharm. Bull. 30 (4): 655–60. doi:10

T helper cell 22 (646 words) [view diff] exact match in snippet view article find links to article

dermal DCs. Th22 cells are known to secrete IL-22, IL-13, IL-26, TNF-α, and granzyme B. Th22 cells express the chemokine receptors CCR4, CCR6, and CCR10 which

Interleukin 10 (4,619 words) [view diff] exact match in snippet view article find links to article

been shown to enhance CD8+ T cell secretion of the cytotoxic molecules Granzyme B and Perforin and potentiate T cell receptor dependent IFNγ secretion

Bacterial therapy (1,342 words) [view diff] exact match in snippet view article find links to article

subunit of the bacterial flagellum) via TLR5 activation. The perforin and granzyme proteins secreted by activated CD8+ T cells efficiently kill tumor cells

Living medicine (941 words) [view diff] exact match in snippet view article find links to article

subunit of the bacterial flagellum) via TLR5 activation. The perforin and granzyme proteins secreted by activated CD8+ T cells efficiently kill tumor cells

DFFA (1,405 words) [view diff] exact match in snippet view article find links to article

(June 2001). "Direct cleavage of the human DNA fragmentation factor-45 by granzyme B induces caspase-activated DNase release and DNA fragmentation". The EMBO

Nancy Thornberry (1,720 words) [view diff] exact match in snippet view article find links to article

Combinatorial Approach Defines Specificities of Members of the Caspase Family and Granzyme B". Journal of Biological Chemistry. 272 (29): 17907–17911. doi:10.1074/jbc

Glypican 3 (2,651 words) [view diff] exact match in snippet view article find links to article

cells can eliminate GPC3-positive cancer cells, by inducing perforin- and granzyme-mediated cell death and reducing Wnt signaling in tumor cells. CAR (hYP7)

Rheumatoid arthritis (17,072 words) [view diff] exact match in snippet view article find links to article

(subscription required) Jonsson AH, Zhang F, Dunlap G, et al. (June 2022). "Granzyme K+ CD8 T cells form a core population in inflamed human tissue". Science

Lichen planus (7,080 words) [view diff] exact match in snippet view article find links to article

mechanisms such as secretion of tumor necrosis factor (TNF)-alpha, secretion of granzyme B, or Fas-Fas ligand interactions. Chemokines are produced by activated

Veto cell (2,148 words) [view diff] exact match in snippet view article find links to article

cognate CD8 T cells by immature dendritic cells: a novel role for perforin, granzyme A, TREM-1, and TLR7". Blood. 120 (8): 1647–57. doi:10.1182/blood-2012-02-410803

Caspase-activated DNase (3,040 words) [view diff] exact match in snippet view article find links to article

(June 2001). "Direct cleavage of the human DNA fragmentation factor-45 by granzyme B induces caspase-activated DNase release and DNA fragmentation". The EMBO

BNIP3 (2,693 words) [view diff] exact match in snippet view article find links to article

metabolic process viral process negative regulation of mitochondrial fusion granzyme-mediated apoptotic signaling pathway mitochondrial outer membrane permeabilization

Seamus Martin (biochemist) (1,192 words) [view diff] exact match in snippet view article

Greenberg, A. H., and Green, D. R. (1996) The cytotoxic cell protease granzyme B initiates apoptosis in a cell-free system by proteolytic processing and

2014 in science (25,483 words) [view diff] exact match in snippet view article find links to article

Intelligence" (AI100). By blocking the activity of an enzyme known as Granzyme b, researchers have slowed aging in the skin of mice. 17 December – A Colorado

Artificial white blood cells (2,429 words) [view diff] exact match in snippet view article find links to article

innate immune system, and they kill pathogens via release of perforin and granzyme to directly destroy cell membranes, release of cytokines such as TNF-α