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alternate case: b cell

Non-Hodgkin lymphoma (3,216 words) [view diff] no match in snippet view article find links to article

dendritic cell sarcoma, extranodal NK-T-cell lymphoma and diffuse large B-cell lymphoma. Human T-cell leukemia virus: associated with adult T-cell lymphoma

B-cell CLL/lymphoma (59 words) [view diff] no match in snippet view article find links to article

B-cell CLL/lymphoma refers to a family of genes associated with certain types of lymphoma and leukemia. Although named for B-cell chronic lymphocytic

Acute lymphoblastic leukemia (7,920 words) [view diff] no match in snippet view article find links to article

less than 10% of adults and less than 5% of children, particularly mature B-cell ALL (Burkitt leukemia) at presentation. The signs and symptoms of acute

EBF1 (1,251 words) [view diff] exact match in snippet view article find links to article

EBF1 gene. EBF1 stands for Early B-Cell Factor 1. EBF1 controls the expression of key proteins required for B cell differentiation, signal transduction

B-cell maturation antigen (1,938 words) [view diff] no match in snippet view article find links to article

B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is

VPREB1 (1,043 words) [view diff] exact match in snippet view article find links to article

apparent MW of 16-18 kDa. It is expressed selectively at the early stages of B cell development, namely, in proB and early preB cells. CD179a has an Ig V domain-like

Hypoglycemia (6,302 words) [view diff] exact match in snippet view article find links to article

failure, liver disease, hormone deficiency, tumors such as insulinomas or non-B cell tumors, inborn errors of metabolism, and several medications. Low blood

Alpha-taxilin (1,060 words) [view diff] no match in snippet view article find links to article

Alpha-taxilin also known as interleukin-14 (IL-14) or high molecular weight B-cell growth factor (HMW-BCGF) is a protein that in humans is encoded by the TXLNA

Polatuzumab vedotin (1,308 words) [view diff] no match in snippet view article find links to article

antibody-drug conjugate medication used for the treatment of diffuse large B-cell lymphoma (cancer). It was developed by the Genentech subsidiary of Roche

Beta cell (3,924 words) [view diff] no match in snippet view article find links to article

Rorsman P (February 1990). "ATP-sensitive K+ channels: a link between B-cell metabolism and insulin secretion". Biochemical Society Transactions. 18

IGLL1 (1,148 words) [view diff] exact match in snippet view article find links to article

gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which

CD180 (776 words) [view diff] exact match in snippet view article find links to article

receptors (TLR). CD180/MD-1, by working in concert with TLR4, controls B cell recognition and signaling of lipopolysaccharide (LPS), a membrane constituent

BCL11A (1,656 words) [view diff] no match in snippet view article find links to article

B-cell lymphoma/leukemia 11A is a protein that in humans is encoded by the BCL11A gene. The BCL11A gene encodes for a regulatory C2H2 type zinc-finger

Loncastuximab tesirine (1,002 words) [view diff] no match in snippet view article find links to article

monoclonal antibody conjugate medication used to treat large B-cell lymphoma and high-grade B-cell lymphoma. It is an antibody-drug conjugate (ADC) composed

PBX1 (1,819 words) [view diff] no match in snippet view article find links to article

Pre-B-cell leukemia transcription factor 1 is a protein that in humans is encoded by the PBX1 gene. The homologous protein in Drosophila is known as extradenticle

International Classification of Diseases for Oncology (9,870 words) [view diff] no match in snippet view article find links to article

rich large B-cell lymphoma Histiocyte-rich large B-cell lymphoma Anaplastic large B-cell lymphoma M9684/3 Malignant lymphoma, large B-cell, diffuse, immunoblastic

Co-stimulation (1,953 words) [view diff] exact match in snippet view article find links to article

B cell binds antigens with its BCR (a membrane-bound antibody), which transfers intracellular signals to the B cell as well as inducing the B cell to

Cladribine (3,642 words) [view diff] no match in snippet view article find links to article

hairy cell leukemia (formally named leukemic reticuloendotheliosis) and B-cell chronic lymphocytic leukemia. Cladribine, sold under the brand name Mavenclad

Toralizumab (188 words) [view diff] no match in snippet view article find links to article

pancreatic islet cell transplantation, and corneal transplantation), and B-cell malignancies such as CLL/small lymphocytic lymphoma, follicular cell lymphoma

Roseola (1,956 words) [view diff] no match in snippet view article find links to article

Roseola, also known as sixth disease, is an infectious disease caused by certain types of human herpes viruses. Most infections occur before the age of

BST1 (1,302 words) [view diff] no match in snippet view article find links to article

line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38

Automated insulin delivery system (3,518 words) [view diff] no match in snippet view article find links to article

Automated insulin delivery systems are automated (or semi-automated) systems designed to assist people with insulin-requiring diabetes, by automatically

Nodal marginal zone B cell lymphoma (200 words) [view diff] exact match in snippet view article find links to article

Nodal marginal zone B cell lymphoma (NMZL) is an uncommon form of marginal-zone lymphoma that can produce colonization of the follicles in the lymph node

PBX2 (843 words) [view diff] no match in snippet view article find links to article

Pre-B-cell leukemia transcription factor 2 is a protein that in humans is encoded by the PBX2 gene. This gene encodes a ubiquitously expressed member of

Immunogenicity (1,818 words) [view diff] exact match in snippet view article find links to article

products that have adaptive immunity: T cell receptors or antibodies (a.k.a. B cell receptors). Antigenicity was more commonly used in the past to refer to

PBX2 (843 words) [view diff] no match in snippet view article find links to article

Pre-B-cell leukemia transcription factor 2 is a protein that in humans is encoded by the PBX2 gene. This gene encodes a ubiquitously expressed member of

12-O-Tetradecanoylphorbol-13-acetate (655 words) [view diff] no match in snippet view article find links to article

cancer [citation needed] TPA has a specific use in cancer diagnostics as a B-cell specific mitogen in cytogenetic testing. Cells must be divided in a cytogenic

Mantle cell lymphoma (4,654 words) [view diff] no match in snippet view article find links to article

and Jaffe in 1991. MCL is a subtype of B-cell lymphoma, due to CD5 positive antigen-naive pregerminal center B-cell within the mantle zone that surrounds

PBX3 (544 words) [view diff] no match in snippet view article find links to article

Pre-B-cell leukemia transcription factor 3 is a protein that in humans is encoded by the PBX3 gene. GRCh38: Ensembl release 89: ENSG00000167081 – Ensembl

Camidanlumab tesirine (513 words) [view diff] no match in snippet view article find links to article

trials for the treatment of B-cell Hodgkin's lymphoma (HL) and non-Hodgkin lymphoma (NHL), and for the treatment of B-cell acute lymphoblastic leukemia

Denintuzumab mafodotin (346 words) [view diff] no match in snippet view article find links to article

designed for the treatment of CD19-positive acute lymphoblastic leukemia and B-cell non-Hodgkin lymphoma. It consists of an anti-CD19 mAb linked to monomethyl

Primary cutaneous follicle center lymphoma (547 words) [view diff] no match in snippet view article find links to article

60% of primary cutaneous B-cell lymphomas (PCBCL);: 373 primary cutaneous marginal zone lymphoma and diffuse large B-cell cell lymphoma, leg type are

Mir-127 (1,084 words) [view diff] no match in snippet view article find links to article

caused a downregulation of B-cell lymphoma 6 protein, a proto-oncogene which is usually hypermutated in diffuse large B-cell lymphoma (DLCL). Moreover

CD320 (528 words) [view diff] case mismatch in snippet view article find links to article

Human Follicular Dendritic Cell Molecule That Stimulates Germinal Center B Cell Growth". J. Exp. Med. 191 (6): 1077–84. doi:10.1084/jem.191.6.1077. PMC 2193124

FOXP1 (1,480 words) [view diff] no match in snippet view article find links to article

strongly associated with inferior survival in patients with diffuse large B-cell lymphoma". Clinical Cancer Research. 11 (3): 1065–1072. doi:10.1158/1078-0432

Galiximab (104 words) [view diff] no match in snippet view article find links to article

Galiximab is a monoclonal antibody designed for the treatment of B-cell lymphoma. As of September 2009[update], it is undergoing Phase III clinical trials

Primary cutaneous marginal zone lymphoma (112 words) [view diff] no match in snippet view article find links to article

cutaneous immunocytoma Marginal zone B-cell lymphoma Mucosa-associated lymphoid tissue lymphoma Cutaneous B-cell lymphoma Skin lesion James, William D

Detumomab (74 words) [view diff] no match in snippet view article find links to article

Detumomab is a mouse monoclonal antibody targeting human B-cell lymphoma. "International Nonproprietary Names (INN) for Pharmaceutical Substances" (PDF)

Activation-induced cytidine deaminase (2,393 words) [view diff] exact match in snippet view article find links to article

produce antibody diversity, but that same mutation process can also lead to B cell lymphoma. This gene encodes a DNA-editing deaminase that is a member of

TCF3 (1,186 words) [view diff] no match in snippet view article find links to article

translocations that are associated with lymphoid malignancies including pre-B-cell acute lymphoblastic leukemia (t(1;19), with PBX1 and t(17;19), with HLF)

IFNB1 (852 words) [view diff] no match in snippet view article find links to article

stimulatory effects of IFN-alpha, -beta, and -gamma on human B-cell proliferation induced by various B-cell mitogens". Clin. Immunol. Immunopathol. 48 (3): 297–306

MEF2C (1,887 words) [view diff] no match in snippet view article find links to article

Binding Site for MEF2C Resulting in Reduced CXCR5 Promoter Activity in B-Cell Lymphoblastic Cell Lines". Front. Immunol. 7 (515): 515. doi:10.3389/fimmu

Tafasitamab (671 words) [view diff] no match in snippet view article find links to article

lenalidomide for the treatment of adults with relapsed or refractory diffuse large B-cell lymphoma (DLBCL). Tafasitamab may cause serious side effects including infusion

Mir-16 microRNA precursor family (2,695 words) [view diff] no match in snippet view article find links to article

colleagues. Karyotyping of chromosome structures from individuals with B-cell chronic lymphocytic leukaemias (B-CLL) found that more than half have alterations

Proliferating angioendotheliomatosis (248 words) [view diff] no match in snippet view article find links to article

an intravascular lymphoma, usually of the diffuse B-cell type, known as intravascular large B-cell lymphoma. It progresses rapidly through involvement

Tau-protein kinase (404 words) [view diff] exact match in snippet view article find links to article

signaling pathway, hedgehog signaling pathway, axon guidance, focal adhesion, b cell receptor signaling pathway, insulin signaling pathway, melanogenesis, alzheimer's

Ken Allen (897 words) [view diff] no match in snippet view article find links to article

Ballad of Ken Allen", was written by David Gersten. Ken Allen developed B-cell lymphoma and was euthanized on December 1, 2000. He was 29 years old. In

Mir-19 microRNA precursor family (3,172 words) [view diff] no match in snippet view article find links to article

miR-19 family can be expressed from: * T-cell acute lymphoblastic leukemia * B-cell lymphomas * Cell lines * Cerebellum * Purkinje cells * HeLa cells Finally

Immunomics (3,831 words) [view diff] no match in snippet view article find links to article

smaller fragments, and tested against T- and B-cells to observe T- and B- cell responses. These classical approaches could only visualize this system

IKZF3 (1,215 words) [view diff] exact match in snippet view article find links to article

Pillai S, Morgan BA, Georgopoulos K (October 1998). "Aiolos regulates B cell activation and maturation to effector state". Immunity. 9 (4): 543–53. doi:10

Belantamab mafodotin (1,128 words) [view diff] no match in snippet view article find links to article

Belantamab mafodotin is a humanized IgG1κ monoclonal antibody against the B-cell maturation antigen (BCMA) conjugated with a cytotoxic agent, maleimidocaproyl

FCRL5 (675 words) [view diff] exact match in snippet view article find links to article

"Altered gene expression upon BCR cross-linking in Burkitt's lymphoma B cell line". Biochem Biophys Res Commun. 277 (1): 124–7. doi:10.1006/bbrc.2000

Copanlisib (814 words) [view diff] exact match in snippet view article find links to article

death by apoptosis and inhibition of proliferation of primary malignant B cell lines. Efficacy resulting in the approval of copanlisib was based on the

T(11:14) (322 words) [view diff] no match in snippet view article

The translocation is mainly found in mantle cell lymphoma, but also in B-cell prolymphocytic leukemia, in plasma cell leukemia, in splenic lymphoma with

Primary mediastinal B-cell lymphoma (843 words) [view diff] no match in snippet view article find links to article

Primary mediastinal B-cell lymphoma, abbreviated PMBL or PMBCL, is a rare type of lymphoma that forms in the mediastinum (the space in between the lungs)

Antibody–drug conjugate (3,943 words) [view diff] no match in snippet view article find links to article

monotherapy for the treatment of adults with relapsed or refractory CD22-positive B-cell precursor acute lymphoblastic leukemia (ALL) on June 30, 2017, under the

NFAT (2,877 words) [view diff] no match in snippet view article find links to article

different receptors like the T-cell receptor (TCR) (PLCG1[citation needed]) or B-cell receptor (BCR) (PLCG2[citation needed]). This activation leads to release

Large-cell lymphoma (301 words) [view diff] no match in snippet view article find links to article

large-B-cell lymphomas Richter's transformation: Diffuse Large B-cell Variant 1) ABC subtype (common) 2) GCB subtype (rare) Activated B-Cell Diffuse Large B-Cell

Rheumatology (1,478 words) [view diff] exact match in snippet view article find links to article

moderate to severe rheumatoid arthritis. The biologic agent rituximab (anti-B cell therapy) is now licensed for use in refractory rheumatoid arthritis. Physiotherapy

PTPRJ (1,340 words) [view diff] no match in snippet view article find links to article

tyrosine phosphatase associated with human CD100 semaphorin at terminal B-cell differentiation stage". Blood. 95 (3): 965–72. doi:10.1182/blood.V95.3.965

ID4 (3,045 words) [view diff] no match in snippet view article find links to article

in the differentiation of fallopian tubes, uterus, cervix and vagina. In B-Cell (B lymphocyte) acute lymphoblastic leukaemia (B-ALL), ID4 is overexpressed

Thyroid lymphoma (591 words) [view diff] no match in snippet view article find links to article

than 2% of lymphomas. Thyroid lymphomas are classified as non–Hodgkin's B-cell lymphomas in a majority of cases, although Hodgkin's lymphoma of the thyroid

Mir-15 microRNA precursor family (1,206 words) [view diff] no match in snippet view article find links to article

cells, therefore hinting at an important role of miR-15/16 in normal CD5+ B-cell homeostasis. The CHEK1 (checkpoint kinase 1) gene, located at chromosome

Tyrosine-protein kinase BLK (847 words) [view diff] exact match in snippet view article find links to article

PMID 7592787. Saouaf SJ, Kut SA, Fargnoli J, et al. (1995). "Reconstitution of the B cell antigen receptor signaling components in COS cells". J. Biol. Chem. 270

PTPN6 (2,292 words) [view diff] exact match in snippet view article find links to article

PMID 9890995. Otipoby KL, Draves KE, Clark EA (November 2001). "CD22 regulates B cell receptor-mediated signals via two domains that independently recruit Grb2

PRKD3 (1,073 words) [view diff] no match in snippet view article find links to article

in response to its activation. This kinase can also be activated after B-cell antigen receptor (BCR) engagement, which requires intact phospholipase C

Daratumumab (1,925 words) [view diff] exact match in snippet view article find links to article

It was granted orphan drug status for multiple myeloma, diffuse large B cell lymphoma, follicular lymphoma, and mantle cell lymphoma. It is available

Zinc transporter ZIP10 (223 words) [view diff] exact match in snippet view article find links to article

B cell apoptotic process positive regulation of protein tyrosine phosphatase activity zinc ion transport ion transport positive regulation of B cell proliferation

Antigen processing (1,763 words) [view diff] exact match in snippet view article find links to article

complementary TCRs) bind this B cell and secrete lymphokines that: Stimulate the B cell to enter the cell cycle The B cell undergoes repeated mitotic cell

Tetherin (2,458 words) [view diff] exact match in snippet view article find links to article

Tetherin has been shown as a Type-I-IFN biomarker using flow cytometry, B cell Tetherin was used as a Cell-Specific Assay for Response to Type I Interferon

RhoH (1,032 words) [view diff] exact match in snippet view article find links to article

analysis of aberrant somatic hypermutation of RhoH gene in diffuse large B cell lymphoma". Leukemia. 21 (8): 1846–7. doi:10.1038/sj.leu.2404717. PMID 17443219

Venetoclax (2,717 words) [view diff] exact match in snippet view article find links to article

deletion or TP53 mutation in adults who are unsuitable for or have failed a B cell receptor pathway inhibitor and for the treatment of CLL in the absence of

ARID domain (609 words) [view diff] no match in snippet view article find links to article

biology, the ARID domain (AT-rich interaction domain; also known as BRIGHT (B-cell Regulator of Ig Heavy chain Transcription) domain)) is a protein domain

MEF2B (1,115 words) [view diff] no match in snippet view article find links to article

diffuse large B-cell lymphoma. In its mutated form, MEF2B can lead to deregulation of the proto-oncogene BCL6 expression in diffuse large B-cell lymphomas

Oblimersen (398 words) [view diff] no match in snippet view article find links to article

treatment for several types of cancer, including chronic lymphocytic leukemia, B-cell lymphoma, and breast cancer. It may kill cancer cells by blocking the production

Virchows Archiv (757 words) [view diff] no match in snippet view article find links to article

Virchows Archiv: European Journal of Pathology is a monthly peer-reviewed medical journal of all aspects of pathology, especially human pathology. It is

Bcl-xL (884 words) [view diff] no match in snippet view article find links to article

B-cell lymphoma-extra large (Bcl-xL), encoded by the BCL2-like 1 gene, is a transmembrane molecule in the mitochondria. It is a member of the Bcl-2 family

CD99 (2,354 words) [view diff] no match in snippet view article find links to article

CD99 than women. In patients with diffuse large B-cell lymphoma (DLBCL) with the germinal center B-cell (GCB, classified according to the Muris algorithm)

Lipid raft (6,662 words) [view diff] exact match in snippet view article find links to article

such as Immunoglobulin E signalling, T cell antigen receptor signalling, B cell antigen receptor signalling, EGF receptor signalling, insulin receptor signalling

Small cleaved cells (276 words) [view diff] no match in snippet view article find links to article

(C83.1) . The "small cleaved cells" are usually centrocytes that express B-cell markers such as CD20. The disease is strongly correlated with the genetic

DNA polymerase mu (702 words) [view diff] no match in snippet view article find links to article

nucleotides to DNA ends during V(D)J recombination, the process by which B-cell and T-cell receptor diversity is generated in the vertebrate immune system

PRDM1 (2,688 words) [view diff] exact match in snippet view article find links to article

differentiation. During B cell development, a B cell can either differentiate into a short-lived plasma cell or into a germinal center B cell after receiving

IFNA21 (432 words) [view diff] exact match in snippet view article find links to article

killer cell activation involved in immune response B cell differentiation defense response B cell proliferation blood coagulation positive regulation

IFNA8 (485 words) [view diff] exact match in snippet view article find links to article

killer cell activation involved in immune response B cell differentiation defense response B cell proliferation blood coagulation positive regulation

IFNA5 (429 words) [view diff] exact match in snippet view article find links to article

killer cell activation involved in immune response B cell differentiation defense response B cell proliferation blood coagulation positive regulation

IFNA6 (394 words) [view diff] exact match in snippet view article find links to article

killer cell activation involved in immune response B cell differentiation defense response B cell proliferation blood coagulation positive regulation

IFNA4 (524 words) [view diff] exact match in snippet view article find links to article

in immune response B cell proliferation humoral immune response defense response to virus type I interferon signaling pathway B cell differentiation T

IFNA10 (481 words) [view diff] exact match in snippet view article find links to article

killer cell activation involved in immune response B cell differentiation defense response B cell proliferation blood coagulation positive regulation

Intraocular lymphoma (814 words) [view diff] no match in snippet view article find links to article

system lymphoma (PCNSL). PCNSL (and PIOL) are most commonly a diffuse large B-cell immunohistologic subtype of non-Hodgkin's lymphoma according to the World

IFNA14 (500 words) [view diff] exact match in snippet view article find links to article

killer cell activation involved in immune response B cell differentiation defense response B cell proliferation blood coagulation positive regulation

BCL10 (1,813 words) [view diff] no match in snippet view article find links to article

B-cell lymphoma/leukemia 10 is a protein that in humans is encoded by the BCL10 gene. Like BCL2, BCL3, BCL5, BCL6, BCL7A, and BCL9, it has clinical significance

Prolymphocytic leukemia (69 words) [view diff] no match in snippet view article find links to article

leukemia is divided into two types according to the kind of cell involved: B-cell prolymphocytic leukemia and T-cell prolymphocytic leukemia. It is usually

Zinc transporter ZIP9 (2,421 words) [view diff] no match in snippet view article find links to article

23 cases of patients with circulation related cancers such as B-cell lymphoma and B-cell chronic lymphocytic leukaemia (CLL). Chimeric genes are a result

List of cancer types (1,143 words) [view diff] exact match in snippet view article find links to article

granulomatosis Mantle cell lymphoma Marginal zone B-cell lymphoma Mast cell leukemia Mediastinal large B cell lymphoma Multiple myeloma/plasma cell neoplasm

Breakthrough infection (2,383 words) [view diff] exact match in snippet view article find links to article

If B cell receptors bind to the antigen and Fc receptors simultaneously bind to the maternal antibody, the Fc receptors send a signal to B cell receptors

Apoptosis regulator BAX (2,092 words) [view diff] exact match in snippet view article find links to article

toxic substance B cell negative selection mitochondrial fusion neuron apoptotic process male gonad development positive regulation of B cell apoptotic process

IFNA17 (580 words) [view diff] exact match in snippet view article find links to article

cell activation involved in immune response B cell differentiation defense response response to virus B cell proliferation blood coagulation positive regulation

Orbital lymphoma (1,338 words) [view diff] exact match in snippet view article find links to article

is still debated. Follicular lymphoma, diffuse large B cell lymphoma, mantle cell lymphoma, B-cell chronic lymphocytic leukemia, peripheral T-cell lymphoma

ELF2 (487 words) [view diff] exact match in snippet view article find links to article

AML1 and mediate opposing effects on AML1-mediated transcription of the B cell-specific blk gene". J. Biol. Chem. 279 (19): 19512–22. doi:10.1074/jbc.M309074200

MorphoSys (1,443 words) [view diff] no match in snippet view article find links to article

with lenalidomide for the treatment of relapsed/refractory diffuse large B-cell lymphoma. The submission was accepted for filing in February 2020, and a

CD300A (574 words) [view diff] exact match in snippet view article find links to article

adhesion negative regulation of NK T cell activation negative regulation of B cell receptor signaling pathway negative regulation of activation of Janus kinase

Monoclonal antibody therapy (4,217 words) [view diff] no match in snippet view article find links to article

alemtuzumab Campath, Lemtrada Genzyme 5/7/2001 intravenous humanized CD52 B-cell chronic lymphocytic leukemia 103948 Link alirocumab Praluent Sanofi Aventis

Aggressive NK-cell leukemia (1,228 words) [view diff] exact match in snippet view article find links to article

to the NK lineage, clonal rearrangements of lymphoid (T cell receptor; B cell receptor) genes are not seen. The genome of the Epstein Barr virus (EBV)

IFNA7 (898 words) [view diff] exact match in snippet view article find links to article

in immune response B cell proliferation humoral immune response defense response to virus type I interferon signaling pathway B cell differentiation T

CDH17 (780 words) [view diff] exact match in snippet view article find links to article

surface receptor linked signal transduction germinal center B cell differentiation B cell differentiation adherens junction organization oligopeptide

Interleukin 21 (2,936 words) [view diff] exact match in snippet view article find links to article

2007). "Essential role of IL-21 in B cell activation, expansion, and plasma cell generation during CD4+ T cell-B cell collaboration". Journal of Immunology

Lymphocytosis (533 words) [view diff] exact match in snippet view article find links to article

lymphoblastic leukemia lymphoma post-splenectomy state CARD11-related congenital B cell lymphocytosis (rare, also known as BENTA disease) Causes of relative lymphocytosis

P2RY8 (474 words) [view diff] no match in snippet view article find links to article

Recurrent mutations in this gene have been associated to cases of diffuse large B-cell lymphoma. P2Y receptor GRCh38: Ensembl release 89: ENSG00000182162 – Ensembl

GPR97 (873 words) [view diff] no match in snippet view article find links to article

cells. Gene-deficient mice revealed that Gpr97 is crucial for maintaining B-cell population via constitutive CREB and NF-κB activities. Human lymphatic endothelial

Seagen (3,161 words) [view diff] no match in snippet view article find links to article

dazcetuzumab (also known as SGN-40 or huS2C6) for the treatment of diffuse large B-cell lymphoma 16 November: initiation of Phase I clinical trial for SGN-75 (INN:

Mediastinal tumors (884 words) [view diff] exact match in snippet view article find links to article

diagnosis of primary mediastinal B cell lymphoma identifies a clinically favorable subgroup of diffuse large B cell lymphoma related to Hodgkin lymphoma"

ABL (gene) (3,504 words) [view diff] exact match in snippet view article

postsynapse Biological process positive regulation of protein phosphorylation B-1 B cell homeostasis regulation of axon extension neuromuscular process controlling

Protein kinase N1 (1,759 words) [view diff] exact match in snippet view article find links to article

DNA-templated B cell apoptotic process negative regulation of protein kinase activity phosphorylation regulation of transcription by RNA polymerase II B cell homeostasis

BCL9 (1,269 words) [view diff] no match in snippet view article find links to article

B-cell CLL/lymphoma 9 protein is a protein that in humans is encoded by the BCL9 gene. BCL9, together with its paralogue gene BCL9L (BCL9 like or BCL9

Amplicon (1,398 words) [view diff] exact match in snippet view article find links to article

implicated in several forms of human cancer including primary mediastinal B cell lymphoma and Hodgkin's lymphoma. In this context the term amplicon can refer

MNDA (797 words) [view diff] exact match in snippet view article find links to article

process B cell receptor signaling pathway cellular defense response regulation of transcription, DNA-templated negative regulation of B cell proliferation

Brentuximab vedotin (2,086 words) [view diff] no match in snippet view article find links to article

brentuximab vedotin in relapsed or refractory CD30-positive NHL, including B-cell neoplasms. These results demonstrated that single-agent brentuximab vedotin

Veltuzumab (283 words) [view diff] no match in snippet view article find links to article

interferon-alpha, a novel and potent immunocytokine for the therapy of B-cell lymphomas". Blood. 114 (18): 3864–71. doi:10.1182/blood-2009-06-228890.

BACH2 (995 words) [view diff] exact match in snippet view article find links to article

Igarashi K, Yokoyama M (August 2000). "Cloning and expression of human B cell-specific transcription factor BACH2 mapped to chromosome 6q15". Oncogene

Bi-specific T-cell engager (1,778 words) [view diff] no match in snippet view article find links to article

under the brand name Epkinly, is used for the treatment of diffuse large B-cell lymphoma. Epcoritamab is a bispecific CD20-directed CD3 T-cell engager.

BCL3 (2,553 words) [view diff] no match in snippet view article find links to article

B-cell lymphoma 3-encoded protein is a protein that in humans is encoded by the BCL3 gene. This gene is a proto-oncogene candidate. It is identified by

Cationic amino acid transporter 4 (503 words) [view diff] no match in snippet view article find links to article

"Comparative analysis of ZAP-70 expression and Ig VH mutational status in B-cell chronic lymphocytic leukemia". Cytometry Part B. 72 (2): 96–102. doi:10

Integrin alpha 4 (1,210 words) [view diff] exact match in snippet view article find links to article

fibronectin. Comparison of alpha 4 beta 1 (VLA-4) and alpha 4 beta 7 on the human B cell line JY". J. Biol. Chem. 267 (12): 8366–70. doi:10.1016/S0021-9258(18)42453-2

KMT2D (3,946 words) [view diff] no match in snippet view article find links to article

development. Knockout studies in mice also show that KMT2D is required for proper B-cell development. KMT2D is partially functionally redundant with KMT2C and is

Ublituximab (805 words) [view diff] no match in snippet view article find links to article

Mahadevan D (April 2018). "Ublituximab for the treatment of CD20 positive B-cell malignancies". Expert Opinion on Investigational Drugs. 27 (4): 407–412

List of histologic stains that aid in diagnosis of cutaneous conditions (254 words) [view diff] no match in snippet view article find links to article

Basal cell carcinoma Primary cutaneous marginal zone lymphoma Diffuse large B-cell lymphoma leg type Bcl-6 Primary cutaneous follicular lymphoma BerEp4 Desmoplastic

Pixantrone (2,031 words) [view diff] no match in snippet view article find links to article

Adult Patients with Multiply Relapsed or Refractory Aggressive Non-Hodgkin B-Cell Lymphomas. The authorization expired in July 2024, after the holder decided

IFNA16 (1,035 words) [view diff] exact match in snippet view article find links to article

killer cell activation involved in immune response B cell differentiation defense response B cell proliferation blood coagulation positive regulation

Selinexor (2,726 words) [view diff] no match in snippet view article find links to article

for selinexor to treat adults with relapsed or refractory diffuse large B-cell lymphoma (DLBCL), not otherwise specified, including DLBCL arising from

Zanubrutinib (1,799 words) [view diff] no match in snippet view article find links to article

open-label, dose-escalation, global, multicenter, single-arm trial of B‑cell malignancies, including 32 previously treated MCL participants treated with

IFNA13 (1,005 words) [view diff] exact match in snippet view article find links to article

killer cell activation involved in immune response B cell differentiation defense response B cell proliferation blood coagulation positive regulation

Toll-like receptor 9 (2,590 words) [view diff] exact match in snippet view article find links to article

regulation of B cell proliferation regulation of toll-like receptor 9 signaling pathway positive regulation of MAPK cascade regulation of B cell differentiation

2007 Montreal Alouettes season (276 words) [view diff] no match in snippet view article find links to article

In October 2007, quarterback Anthony Calvillo's wife was diagnosed with B-cell lymphoma and non-Hodgkin's cancer of the lymph glands or nodes; Calvillo

Adenosine deaminase (2,965 words) [view diff] exact match in snippet view article find links to article

apoptotic process in utero embryonic development negative regulation of mature B cell apoptotic process nucleotide metabolic process response to vitamin E positive

PLCG2 (1,405 words) [view diff] exact match in snippet view article find links to article

Garcia-Lloret M, Wahl MI, Rawlings DJ (August 2000). "Engagement of the human pre-B cell receptor generates a lipid raft-dependent calcium signaling complex". Immunity

Corepressor (2,462 words) [view diff] no match in snippet view article find links to article

diseases. BCL6 upregulation is observed in cancers such as diffuse large B-cell lymphomas (DLBCLs), colorectal cancer, and lung cancer. BCL-6 corepressor

CD43 (1,283 words) [view diff] no match in snippet view article find links to article

CD3 antigen. However, it may be useful as part of a panel to demonstrate B-cell lymphoblastic lymphoma, since the malignant cells in this condition are

Richard Ramirez (6,956 words) [view diff] no match in snippet view article find links to article

remorse for his crimes. He died on June 7, 2013, of complications from B-cell lymphoma while awaiting execution on Californian death row. Ricardo Leyva

Transforming growth factor beta (8,184 words) [view diff] exact match in snippet view article find links to article

lymphocytes. TGF-β inhibits B cell proliferation. The exact mechanism is unknown, but there is evidence that TGF-β inhibits B cell proliferation by inducing

Multiple myeloma (13,217 words) [view diff] exact match in snippet view article find links to article

associated with MM cells is generally taken to be either an activated memory B cell or the precursor to plasma cells, the plasmablast. The immune system keeps

Parker Price-Miller (224 words) [view diff] no match in snippet view article find links to article

Law Firm". In October 2021, Price-Miller announced he was diagnosed with B-cell lymphoma, the most common form of Non-Hodgkin's lymphoma. (key) (Bold –

John Kanzius (1,282 words) [view diff] no match in snippet view article find links to article

undergoing chemotherapy for treatment of non-Hodgkin's lymphoma. He died of B-cell leukemia with complications from pneumonia without seeing FDA approval and

HLA-DR (2,294 words) [view diff] no match in snippet view article find links to article

These cells then bind to antigens on the surface of B-cells stimulating B-cell proliferation. The primary function of HLA-DR is to present peptide antigens

Humanized antibody (1,806 words) [view diff] no match in snippet view article find links to article

into a human antibody framework. Alemtuzumab is approved for treatment of B-cell chronic lymphocytic leukemia and is currently in clinical trials for a variety

FCRL3 (1,917 words) [view diff] exact match in snippet view article find links to article

preferentially expressed on B cell, and is along the FCRL6 the only gene from this family which is expressed also outside B-cell lineage, as it has been detected

Abexinostat (685 words) [view diff] no match in snippet view article find links to article

to Xynomic. As of 2013[update], it was in Phase II clinical trials for B-cell lymphoma.[needs update] Pre-clinical study suggests the potential for treatment

Phosphoinositide 3-kinase inhibitor (5,402 words) [view diff] no match in snippet view article find links to article

p110 and HDAC inhibitor): A phase II trial in patients with diffuse large B-cell lymphoma (DLBCL) was completed in 2019 but its results have not yet been

Helicobacter pylori (16,816 words) [view diff] no match in snippet view article find links to article

tissue (MALT) lymphomas and gastric cancer. Less commonly, diffuse large B-cell lymphoma of the stomach is a risk. Infection with H. pylori is responsible

Membrane glycoproteins (53 words) [view diff] no match in snippet view article find links to article

Alpha 1-antichymotrypsin Apolipoprotein H CD70 Asialoglycoprotein Avidin B-cell activating factor 4-1BB ligand Cholesterylester transfer protein Clusterin

Human T-lymphotropic virus 2 (1,206 words) [view diff] exact match in snippet view article find links to article

lymphoproliferative disease that was described as having characteristics similar to the B cell disorder, hairy cell leukemia. HTLV-2 was identified in a second patient

Small modular immunopharmaceutical (477 words) [view diff] no match in snippet view article find links to article

B-cell malignancies". Current Opinion in Investigational Drugs. 10 (12): 1383–1390. PMID 19943209. TruEmergent: TRU-016 for the Treatment of B-Cell Malignancies

WHO classification of tumours of the central nervous system (1,416 words) [view diff] no match in snippet view article find links to article

large B-cell lymphoma of the CNS 9.1.1.2 Immunodeficiency-associated CNS lymphoma 9.1.1.3 Lymphomatoid granulomatosis 9.1.1.4 Intravascular large B-cell lymphoma

NFATC2 (1,445 words) [view diff] exact match in snippet view article find links to article

nucleoplasm nucleus cytosol ribonucleoprotein complex Biological process B cell receptor signaling pathway regulation of transcription, DNA-templated cytokine

MALT1 (2,753 words) [view diff] no match in snippet view article find links to article

two central immunoglobulin-like domains involved in the binding to the B-cell lymphoma 10 (Bcl10) protein and a caspase-like domain. The death domain

EpiVacCorona (3,887 words) [view diff] no match in snippet view article find links to article

the developers of EpiVacCorona represent the protein regions containing B-cell epitopes that should be recognized by the human immune system. These peptides

GNA13 (1,921 words) [view diff] no match in snippet view article find links to article

Recurrent mutations in this gene have been associated to cases of diffuse large B-cell lymphoma. G12/G13 alpha subunits G protein-coupled receptor Heterotrimeric

Aurora kinase C (1,969 words) [view diff] no match in snippet view article find links to article

"Aurora-C kinase supports mitotic progression in the absence of Aurora-B". Cell Cycle. 8 (18): 2984–94. doi:10.4161/cc.8.18.9591. PMID 19713763. "Aurora

CKAP2 (818 words) [view diff] no match in snippet view article find links to article

head-and-neck squamous-cell carcinoma, B-cell prolymphocytic leukemia, non-Hodgkin lymphoma, and in more than half cases of B-cell chronic lymphocytic leukemia

Immunological memory (2,961 words) [view diff] exact match in snippet view article find links to article

involved in the primary immune response the memory B cell response is slightly different. The memory B cell has already undergone clonal expansion, differentiation

CD278 (1,644 words) [view diff] exact match in snippet view article find links to article

PMID 12456021. Shilling RA, Bandukwala HS, Sperling AI (Oct 2006). "Regulation of T:B cell interactions by the inducible costimulator molecule: does ICOS "induce"

Interleukin-6 receptor (1,446 words) [view diff] exact match in snippet view article find links to article

Pahwa S (1993). "HIV-gp 160-induced T cell-dependent B cell differentiation. Role of T cell-B cell activation molecule and IL-6". J. Immunol. 150 (6):

BCAP31 (1,228 words) [view diff] no match in snippet view article find links to article

B-cell receptor-associated protein 31 is a protein that in humans is encoded by the BCAP31 gene. BCAP31 has been shown to interact with: APP, BCL2L1, BCL2

IFNW1 (1,704 words) [view diff] exact match in snippet view article find links to article

killer cell activation involved in immune response B cell differentiation defense response B cell proliferation response to virus positive regulation

Asymptomatic (846 words) [view diff] no match in snippet view article find links to article

diverticulum Microvenular hemangioma Mitral valve prolapse Monkeypox Monoclonal B-cell lymphocytosis Myelolipoma Nonalcoholic fatty liver disease Optic disc pit

IGHM (900 words) [view diff] exact match in snippet view article find links to article

PMC 329453. PMID 1904154. Tsubata T, Reth M (1990). "The products of pre-B cell-specific genes (lambda 5 and VpreB) and the immunoglobulin mu chain form

Cutaneous lymphoma (102 words) [view diff] no match in snippet view article find links to article

that affect the skin:[citation needed] Cutaneous T-cell lymphoma Cutaneous B-cell lymphoma Paller, Amy S.; Mancini, Anthony J. (2015). Hurwitz Clinical Pediatric

Alemtuzumab (1,884 words) [view diff] no match in snippet view article find links to article

Lemtrada aimed at multiple sclerosis. Alemtuzumab is used for the treatment of B-cell chronic lymphocytic leukemia in people who have been treated with alkylating

Lisocabtagene maraleucel (1,685 words) [view diff] no match in snippet view article find links to article

under the brand name Breyanzi, is a cell-based gene therapy used to treat B-cell lymphomas, including follicular lymphoma. Side effects include hypersensitivity

Ketan J. Patel (1,499 words) [view diff] exact match in snippet view article find links to article

PMID 15327776. Patel, K.J.; Neuberger, M.S. (1993). "Antigen presentation by the B cell antigen receptor is driven by the αβ sheath and occurs independently of

IGHV@ (602 words) [view diff] no match in snippet view article find links to article

gene. IGHV is the immunoglobulin heavy chain variable region genes; in B-cell neoplasms like chronic lymphocytic leukemia, mutations of IGHV are associated

HVCN1 (1,408 words) [view diff] exact match in snippet view article find links to article

Takeuchi A, et al. (Nov 2007). "Cloning of B cell-specific membrane tetraspanning molecule BTS possessing B cell proliferation-inhibitory function". European

Homing (hematopoietic) (250 words) [view diff] exact match in snippet view article

2004). "Chemokine receptors that mediate B cell homing to secondary lymphoid tissues are highly expressed in B cell chronic lymphocytic leukemia and non-Hodgkin

Juno Therapeutics (842 words) [view diff] no match in snippet view article find links to article

and Eureka Therapeutics for a novel, fully human binding domain targeting B-cell maturation antigen. In January 2018, Celgene announced it would acquire

Dedicator of cytokinesis protein 10 (646 words) [view diff] no match in snippet view article find links to article

response to the cytokine IL-4. This suggests that Dock10 may have a role in B-cell activation and proliferation. Another study in 2006 identified Dock10 as

CD83 (2,181 words) [view diff] exact match in snippet view article find links to article

with rate of activation of B lymphocytes and it is under control of the B cell receptor, CD40, or Toll-like receptor activation, as in other lymphocytes

List of therapeutic monoclonal antibodies (4,345 words) [view diff] no match in snippet view article find links to article

D; Lindhofer, H; Kolb, HJ; et al. (2008). "Immunotherapy of recurrent B–cell malignancies after allo SCT with Bi20 (FBTA05), a trifunctional anti-CD3

Isatuximab (3,418 words) [view diff] no match in snippet view article find links to article

studies of B-cell malignancies, isatuximab demonstrated greater pro-apoptotic activity than daratumumab. It more effectively disrupted B-cell receptor signaling

Gray zone lymphoma (73 words) [view diff] no match in snippet view article find links to article

B-cell lymphomas. Traverse-Glehen A, Mediastinal gray zone lymphoma: the missing link between classic Hodgkin's lymphoma and mediastinal large B-cell

Chemoimmunotherapy (1,033 words) [view diff] no match in snippet view article find links to article

chemoimmunotherapy regimen is CHOP combined with rituximab (CHOP-R) for B-cell non-Hodgkin lymphomas. Cancer treatment has progressed to combine different

Hematologic disease (537 words) [view diff] no match in snippet view article find links to article

Chronic myelogenous leukemia (CML) T-cell prolymphocytic leukemia (T-PLL) B-cell prolymphocytic leukemia (B-PLL) Chronic neutrophilic leukemia (CNL) Hairy

Salivary gland tumour (1,922 words) [view diff] exact match in snippet view article find links to article

Hematolymphoid tumours Hodgkin lymphoma Diffuse large B-cell lymphoma Extranodal marginal zone B cell lymphoma Secondary tumours (i.e. a tumour which has

Protein BTG1 (1,792 words) [view diff] no match in snippet view article find links to article

be involved in a t(8;12)(q24;q22) chromosomal translocation in a case of B-cell chronic lymphocytic leukemia. It is a member of a family of antiproliferative

Chemoimmunotherapy (1,033 words) [view diff] no match in snippet view article find links to article

chemoimmunotherapy regimen is CHOP combined with rituximab (CHOP-R) for B-cell non-Hodgkin lymphomas. Cancer treatment has progressed to combine different

Cortisol (8,406 words) [view diff] no match in snippet view article find links to article

inflammation. It is used to treat conditions resulting from overactivity of the B-cell-mediated antibody response. Examples include inflammatory and rheumatoid

Otlertuzumab (105 words) [view diff] no match in snippet view article find links to article

Abdolalizadeh J, Khalili S (December 2018). "Anti-CD37 targeted immunotherapy of B-Cell malignancies". Biotechnology Letters. 40 (11–12): 1459–1466. doi:10.1007/s10529-018-2612-6

SWAP70 (699 words) [view diff] exact match in snippet view article find links to article

Herndier B, Wabl M, Ferrick D (Apr 2000). "Association of SWAP-70 with the B cell antigen receptor complex". Proc Natl Acad Sci U S A. 97 (5): 2180–4. Bibcode:2000PNAS

ROR1 (1,200 words) [view diff] no match in snippet view article find links to article

"Unique cell surface expression of receptor tyrosine kinase ROR1 in human B-cell chronic lymphocytic leukemia". Clinical Cancer Research. 14 (2): 396–404

ETS1 (1,811 words) [view diff] exact match in snippet view article find links to article

partial defects in bone marrow B cell development with reduced cellularity and inefficient transition from pro-B to pre-B cell stages. Meta-analyses of multiple

Cirmtuzumab (135 words) [view diff] no match in snippet view article find links to article

NCT03420183 for "A Study of Cirmtuzumab and Ibrutinib in Patients With B-Cell Lymphoid Malignancies" at ClinicalTrials.gov "1st Mantle Cell Lymphoma Patient

Thyroxine-binding proteins (46 words) [view diff] no match in snippet view article find links to article

Alpha 1-antichymotrypsin Apolipoprotein H CD70 Asialoglycoprotein Avidin B-cell activating factor 4-1BB ligand Cholesterylester transfer protein Clusterin

WHO Disease Staging System for HIV Infection and Disease in Children (439 words) [view diff] exact match in snippet view article find links to article

herpes simplex infection Acquired HIV-associated rectal fistula Cerebral or B cell non-Hodgkin lymphoma Progressive multifocal leukoencephalopathy (PML) HIV-associated

Urelumab (1,121 words) [view diff] no match in snippet view article find links to article

nivolumab (NCT02253992) for metastatic solid tumors, NSCLC, melanoma, B-cell non-Hodgkin lymphoma, colorectal cancer, and multiple myeloma. A biomarker

CD47 (4,272 words) [view diff] no match in snippet view article find links to article

extracellular domain. Similarly, CD47 ligation rapidly induces apoptosis in B-cell chronic lymphocytic leukemia (CLL) cells. Treatment with a disulfide-linked

Blue Gender (2,605 words) [view diff] no match in snippet view article find links to article

overrun by the Blue-alien insectoid creatures containing a newly evolved B-cell, that kill and harvest humans for food. Most of the surviving human race

CHRNB2 (1,086 words) [view diff] exact match in snippet view article find links to article

process behavioral response to nicotine regulation of dendrite morphogenesis B cell activation neuromuscular synaptic transmission synaptic transmission involved

ETV6 (4,620 words) [view diff] exact match in snippet view article find links to article

hematological (e.g. chronic myelomonocytic leukemia, acute myelocytic leukemia, B cell acute lymphoblastic leukemia, mixed phenotype acute leukemia, Myelodysplastic

Proteoglycan (835 words) [view diff] no match in snippet view article find links to article

Alpha 1-antichymotrypsin Apolipoprotein H CD70 Asialoglycoprotein Avidin B-cell activating factor 4-1BB ligand Cholesterylester transfer protein Clusterin

Agnatha (2,850 words) [view diff] exact match in snippet view article find links to article

vertebrates diversify their repertoire of immunoglobulin domain-based T and B cell antigen receptors mainly through the rearrangement of V(D)J gene segments

Hydroa vacciniforme (596 words) [view diff] no match in snippet view article find links to article

lymphoproliferative disease such as T-cell lymphoma, T-cell leukemia, B-cell lymphoma, and B-cell leukemia. In many children hydroa vacciniforme regresses spontaneously

Radioligand (4,367 words) [view diff] no match in snippet view article find links to article

ligand CD20 on human B-cells. CD20 is a membrane spanning protein found on B-cell lymphocytes that is a tumor marker as it is in higher concentration in cancer

Minimal change disease (1,951 words) [view diff] exact match in snippet view article find links to article

T cells, increased markers for B cell activation during a relapse of minimal change disease, and alterations in B cell sub-classes during minimal change

CIITA (1,097 words) [view diff] exact match in snippet view article find links to article

involved in the pathogenesis of Hodgkin lymphoma and primary mediastinal B cell lymphoma. CIITA mRNA can only be detected in human leukocyte antigen (HLA)

Testican (239 words) [view diff] no match in snippet view article find links to article

Alpha 1-antichymotrypsin Apolipoprotein H CD70 Asialoglycoprotein Avidin B-cell activating factor 4-1BB ligand Cholesterylester transfer protein Clusterin

Beta-actin (1,091 words) [view diff] no match in snippet view article find links to article

Recurrent mutations in this gene have been associated to cases of diffuse large B-cell lymphoma. De novo gain-of-function mutations in this gene is associated

Attenuated vaccine (4,227 words) [view diff] exact match in snippet view article find links to article

receptors. T-cells can then recognize this presentation and bind to the B cell, resulting in clonal proliferation. This also helps IgM and plasma cells

Forodesine (362 words) [view diff] no match in snippet view article find links to article

patients with T-cell acute lymphoblastic leukemia (T-ALL) and for treatment of B-cell acute lymphocytic leukemia (B-ALL). Forodesine was originally discovered

PBX (99 words) [view diff] no match in snippet view article find links to article

Susuhunan of Surakarta in Java, Indonesia Polymer-bonded explosive Pre-B-cell leukemia homeobox Private branch exchange, a telephone exchange that serves

Bone marrow failure (1,256 words) [view diff] no match in snippet view article find links to article

identify genetic abnormalities, and rule out other entities such as leukemia. B-cell lymphopenia has been observed in some patients with MECOM deficiency but

Transient receptor potential channel (5,537 words) [view diff] exact match in snippet view article find links to article

"TRPM4 expression is associated with activated B cell subtype and poor survival in diffuse large B cell lymphoma". Histopathology. 71 (1): 98–111. doi:10

BCL6B (344 words) [view diff] no match in snippet view article find links to article

B-cell CLL/lymphoma 6 member B protein is a protein that in humans is encoded by the BCL6B gene. GRCh38: Ensembl release 89: ENSG00000161940 – Ensembl

Calicheamicin (1,505 words) [view diff] no match in snippet view article find links to article

17, 2017, for use in the treatment of adults with relapsed or refractory B-cell precursor acute lymphoblastic leukemia. Calicheamicin γ1 and the related

Death receptor 6 (1,067 words) [view diff] exact match in snippet view article find links to article

apoptotic process oligodendrocyte apoptotic process negative regulation of B cell proliferation neuron apoptotic process humoral immune response myelination

Clone (586 words) [view diff] no match in snippet view article find links to article

County Monaghan, a town in Ireland Clones railway station, Ireland Clone (B-cell), a lymphocyte clone, the massive presence of which may indicate a pathological

GALNAC4S-6ST (656 words) [view diff] exact match in snippet view article find links to article

PMID 9628581. Verkoczy LK, Marsden PA, Berinstein NL (Oct 1998). "hBRAG, a novel B cell lineage cDNA encoding a type II transmembrane glycoprotein potentially involved

Quilizumab (336 words) [view diff] exact match in snippet view article find links to article

Matthews JG, O'Byrne PM (July 2014). "Targeting membrane-expressed IgE B cell receptor with an antibody to the M1 prime epitope reduces IgE production"

NLRP11 (1,272 words) [view diff] exact match in snippet view article find links to article

NLRP11 is expressed mainly in immune cells, B cells, myeloid cells, and B cell lymphoma cell lines. NLRP11 is involved in the regulation of inflammatory

Indometacin farnesil (122 words) [view diff] exact match in snippet view article find links to article

S, Yanagida T, Kawai M, Kikuchi H (November 1999). "Inhibition of human B cell activation by a novel nonsteroidal anti-inflammatory drug, indometacin famesil"

CD74 (2,221 words) [view diff] exact match in snippet view article find links to article

regulation of peptidyl-tyrosine phosphorylation negative regulation of mature B cell apoptotic process regulation of macrophage activation negative regulation

CD 205 (548 words) [view diff] exact match in snippet view article find links to article

molecule which is functionally associated with the IL-4 receptor modulates B cell phenotype and is a novel member of the human macrophage mannose receptor

Clonal selection algorithm (361 words) [view diff] no match in snippet view article find links to article

selection ALGorithm AIRS: The Artificial Immune Recognition System BCA: The B-Cell Algorithm Artificial immune system Biologically inspired computing Computational

IFNA2 (2,608 words) [view diff] exact match in snippet view article find links to article

surface receptor signaling pathway B cell proliferation humoral immune response type I interferon signaling pathway B cell differentiation positive regulation

Clodoveo Ferri (1,573 words) [view diff] no match in snippet view article find links to article

(cryoglobulinemic vasculitis) and in a significant percentage of patients with B-cell non-Hodgkin's lymphoma. Ferri is a member of the SIR (Italian Society of

LIG4 syndrome (400 words) [view diff] exact match in snippet view article find links to article

essential in V(D)J recombination, the mechanism by which immunoglobulins, B cell and T cell receptors are formed, patients with LIG4 syndrome may have less

List of MeSH codes (D12.776.124) (3,780 words) [view diff] no match in snippet view article

700 – pyroglobulins MeSH D12.776.124.486.485.950 – receptors, antigen, b-cell MeSH D12.776.124.486.485.950.500 – antigens, cd79 MeSH D12.776.124.790.106

Ruxolitinib (2,136 words) [view diff] no match in snippet view article find links to article

investigated for plaque psoriasis, alopecia areata, relapsed diffuse large B-cell lymphoma, and peripheral T-cell lymphoma. In February 2016, a phase III

Protein BTG4 (437 words) [view diff] no match in snippet view article find links to article

family member 4 is a protein that in humans is encoded by the BTG4 gene (B-cell translocation gene 4). BTG4 has anti-proliferative properties and can induce

Phosphoinositide phospholipase C (2,202 words) [view diff] exact match in snippet view article find links to article

pathways necessary for antigen mediated B cell activation are necessary for B cell development from CLPs. In B cell signaling, PI 3-kinase is recruited to

IGL@ (926 words) [view diff] exact match in snippet view article find links to article

locus includes V (variable), J (joining), and C (constant) segments. During B cell development, a recombination event at the DNA level joins a single V segment

Cell culture (8,505 words) [view diff] exact match in snippet view article find links to article

of an immunised animal are combined with an immortal myeloma cell line (B cell lineage) to produce a hybridoma which has the antibody specificity of the

Serum B-cell maturation antigen (2,633 words) [view diff] no match in snippet view article find links to article

Serum B-cell maturation antigen (sBCMA) is the cleaved form of B-cell maturation antigen (BCMA), found at low levels in the serum of normal patients and

MIRN21 (2,342 words) [view diff] exact match in snippet view article find links to article

upregulated miRNAs in solid tumours, and its high levels were first described in B cell lymphomas. Overall, miR-21 is considered to be a typical 'onco-miR', which

PTK2B (1,887 words) [view diff] exact match in snippet view article find links to article

positive regulation of JNK cascade regulation of angiogenesis marginal zone B cell differentiation negative regulation of muscle cell apoptotic process positive

CXCR4 (2,660 words) [view diff] no match in snippet view article find links to article

recently identified in patients with Waldenström's macroglobulinemia, a B-cell malignancy. The presence of CXCR4 WHIM mutations has been associated with

Pete Van Wieren (957 words) [view diff] no match in snippet view article find links to article

April 2010. On November 4, 2009, Van Wieren was diagnosed with cutaneous B-cell lymphoma. He suffered a relapse and additional rounds of chemotherapy after

DLEU2 (647 words) [view diff] no match in snippet view article find links to article

potential tumour suppressor gene and is often deleted in patients with B-cell chronic lymphocytic leukemia. Long non-coding RNA "Human PubMed Reference:"

Asialoglycoprotein (172 words) [view diff] no match in snippet view article find links to article

Alpha 1-antichymotrypsin Apolipoprotein H CD70 Asialoglycoprotein Avidin B-cell activating factor 4-1BB ligand Cholesterylester transfer protein Clusterin

IFNK (2,561 words) [view diff] exact match in snippet view article find links to article

involved in immune response B cell differentiation defense response response to virus natural killer cell activation B cell proliferation regulation of

Immunoreceptor tyrosine-based activation motif (1,268 words) [view diff] exact match in snippet view article find links to article

of the T cell receptor complex, the CD79-alpha and -beta chains of the B cell receptor complex, and certain Fc receptors. The tyrosine residues within

Mir-339 microRNA precursor family (640 words) [view diff] no match in snippet view article find links to article

Shen B (January 2009). "Differential microRNA expression in childhood B-cell precursor acute lymphoblastic leukemia". Pediatric Hematology and Oncology

Infectious causes of cancer (5,214 words) [view diff] no match in snippet view article find links to article

Epstein–Barr virus-positive diffuse large B-cell lymphomas, not otherwise specified, diffuse large B-cell lymphomas associated with chronic inflammation

Protein A (1,860 words) [view diff] exact match in snippet view article find links to article

CS, Silverman GJ (May 2003). "Death by a B cell superantigen: In vivo VH-targeted apoptotic supraclonal B cell deletion by a Staphylococcal Toxin". The

HMGB3 (389 words) [view diff] exact match in snippet view article find links to article

transcription, DNA-templated DNA geometric change negative regulation of B cell differentiation negative regulation of myeloid cell differentiation chromatin

Aggrecan (1,985 words) [view diff] exact match in snippet view article find links to article

Schwartz-Albiez R (1997). "Secreted chondroitin sulfate proteoglycan of human B cell lines binds to the complement protein C1q and inhibits complex formation

Monoclonal gammopathy (684 words) [view diff] no match in snippet view article find links to article

following:[citation needed] Leukemias and lymphomas of various types, but usually B-cell non-Hodgkin lymphomas with a plasma cell component. Myeloma Plasmacytoma

Pidilizumab (301 words) [view diff] no match in snippet view article find links to article

encouraging results by 2011 from phase II clinical trials for diffuse large B-cell lymphoma. A phase II open-label study in combination for relapsed follicular