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Longer titles found: Endoplasmic reticulum stress in beta cells (view)

searching for Beta cell 129 found (227 total)

alternate case: beta cell

KATP (137 words) [view diff] no match in snippet view article find links to article

is also the ATP-sensitive potassium channel responsible for pancreatic beta-cell insulin release. KATP (101.9 FM, "The Bull") is a radio station serving
Permanent neonatal diabetes (412 words) [view diff] exact match in snippet view article find links to article
mutations of the KCNJ11 gene, which codes for the Kir6.2 subunit of the beta cell KATP channel. This disease is considered to be a type of maturity onset
Kir6.2 (1,084 words) [view diff] no match in snippet view article find links to article
Siddiqui J, Ellard S (2006). "Mutations in the genes encoding the pancreatic beta-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) in diabetes mellitus
KLF11 (1,396 words) [view diff] exact match in snippet view article find links to article
neurotransmitter, fat, and sugar metabolism, specifically pancreatic beta cell function. Defects in KLF11 affect glucose metabolism, insulin transcription
Diamyd Medical (194 words) [view diff] exact match in snippet view article find links to article
need to be induced to insulin producing beta cell auto-antigens such as for example GAD65; third, the beta cell mass need to be restored with for example
Carboxypeptidase E (1,883 words) [view diff] no match in snippet view article find links to article
protein in pancreatic beta-cells, leading to beta-cell dysfunction (hyperproinsulinemia) and increased beta-cell apoptosis (via an increase in ER-stress)
Zinc transporter 8 (892 words) [view diff] no match in snippet view article find links to article
PMID 21099294. Chimienti F, Favier A, Seve M (2006). "ZnT-8, a pancreatic beta-cell-specific zinc transporter". Biometals. 18 (4): 313–7. doi:10.1007/s10534-005-3687-9
NEUROD1 (1,238 words) [view diff] exact match in snippet view article find links to article
Hagman DK, Parazzoli SD, Poitout V, Stein R (March 2005). "The islet beta cell-enriched MafA activator is a key regulator of insulin gene transcription"
Neurogenin-3 (1,717 words) [view diff] exact match in snippet view article find links to article
treatment induces acinar cell reprogramming and regenerates functional beta cell mass in diabetic mice". Nature Biotechnology. 32 (1): 76–83. doi:10.1038/nbt
MAFA (gene) (757 words) [view diff] exact match in snippet view article
Parazzoli Susan D; Poitout Vincent; Stein Roland (Mar 2005). "The islet beta cell-enriched MafA activator is a key regulator of insulin gene transcription"
Secretory Pathway Ca²⁺ ATPase (348 words) [view diff] exact match in snippet view article find links to article
"Intraorganellar calcium and pH control proinsulin cleavage in the pancreatic beta cell via two distinct site-specific endopeptidases". Nature. 333 (6168): 93–96
MAPK8IP1 (1,323 words) [view diff] no match in snippet view article find links to article
gene. The protein encoded by this gene is a regulator of the pancreatic beta-cell function. It is highly similar to JIP-1, a mouse protein known to be a
Tameka A. Clemons (1,163 words) [view diff] no match in snippet view article find links to article
investigates the aberrant biochemical signalling pathways that result in beta-cell death in Type 2 Diabetes. She seeks to understand how amylin and uncoupling
Regenerating protein family (598 words) [view diff] exact match in snippet view article find links to article
high levels of IL-22 receptor and IL-22 has been shown to induce islet beta cell regeneration. Parikh A, Stephan AF, Tzanakakis ES (2012). "Regenerating
African grass rat (737 words) [view diff] exact match in snippet view article find links to article
hyperglycemia and beta cell failure resulting in depressed insulin and end-stage diabetes that includes severe ketosis. The beta cell failure follows the
Omega-7 fatty acid (1,030 words) [view diff] no match in snippet view article find links to article
"Unsaturated fatty acids as cytoprotective agents in the pancreatic beta-cell". Prostaglandins, Leukotrienes, and Essential Fatty Acids. 82 (4–6): 231–6
ABCC8 (1,086 words) [view diff] no match in snippet view article find links to article
Siddiqui J, Ellard S (2006). "Mutations in the genes encoding the pancreatic beta-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) in diabetes mellitus
Amylin family (363 words) [view diff] exact match in snippet view article find links to article
Nishi M, Sanke T, Nagamatsu S (1990). "Islet amyloid polypeptide. A new beta cell secretory product related to islet amyloid deposits". J. Biol. Chem. 265
Conophylline (980 words) [view diff] exact match in snippet view article find links to article
beneficial activity on animal model of diabetes. It is researched as novel beta cell differentiating factor both alone and with compounds such as betacellulin-delta4
Anne Beloff-Chain (523 words) [view diff] no match in snippet view article find links to article
and obesity. One of her most significant discoveries was that levels of beta-cell-tropin, an insulin secretagogue hormone, were elevated in the blood of
G6PC2 (755 words) [view diff] exact match in snippet view article find links to article
Nathenson SG, Santamaria P, DiLorenzo TP (2003). "Identification of the beta cell antigen targeted by a prevalent population of pathogenic CD8+ T cells
Otelixizumab (678 words) [view diff] exact match in snippet view article find links to article
Phase 2 study. These data demonstrated otelixizumab’s ability to preserve beta cell function, as measured by C-peptide, in patients up to 18 months after
HLA-A24 (759 words) [view diff] no match in snippet view article find links to article
to acute-onset and early complete beta-cell destruction in type 1 diabetes: longitudinal study of residual beta-cell function". Diabetes. 55 (6): 1862–8
Shuvo Roy (621 words) [view diff] exact match in snippet view article find links to article
transport (especially oxygen, glucose, and insulin) to achieve optimal beta cell performance, while the ultra-selective pore characteristic of the SNM
Platelet-derived growth factor (2,831 words) [view diff] exact match in snippet view article find links to article
demonstrated to prevent islet beta cell proliferation in both animal and human cells and its re-expression triggered beta cell proliferation and corrected
KLF7 (529 words) [view diff] no match in snippet view article find links to article
adipocytes and inhibits glucose-induced insulin secretion in pancreatic beta-cell line". Mol. Endocrinol. 20 (4): 844–56. doi:10.1210/me.2005-0138. PMID 16339272
ATP2C1 (1,004 words) [view diff] no match in snippet view article find links to article
"Role for plasma membrane-related Ca2+-ATPase-1 (ATP2C1) in pancreatic beta-cell Ca2+ homeostasis revealed by RNA silencing". Diabetes. 53 (2): 393–400
TRPM (804 words) [view diff] no match in snippet view article find links to article
Vennekens, R (31 March 2017). "Steviol glycosides enhance pancreatic beta-cell function and taste sensation by potentiation of TRPM5 channel activity"
RPH3AL (781 words) [view diff] no match in snippet view article find links to article
insulin-containing secretory granules and is essential for pancreatic beta-cell exocytosis". Molecular Endocrinology. 18 (1): 117–26. doi:10.1210/me.2003-0300
Neurohormone (1,029 words) [view diff] exact match in snippet view article find links to article
cells secrete acetylcholine as a non-neuronal paracrine signal priming beta cell function in humans". Nature Medicine. 17 (7): 888–92. doi:10.1038/nm.2371
CDX4 (gene) (802 words) [view diff] no match in snippet view article
"Cdx4 is required in the endoderm to localize the pancreas and limit beta-cell number". Development. 135 (5): 919–29. doi:10.1242/dev.010660. PMID 18234725
PRKAA2 (969 words) [view diff] exact match in snippet view article find links to article
of AMP-activated protein kinase in the regulation by glucose of islet beta cell gene expression". Proc. Natl. Acad. Sci. U.S.A. 97 (8): 4023–8. Bibcode:2000PNAS
Decoy receptor 2 (897 words) [view diff] no match in snippet view article find links to article
"TNF-related apoptosis-inducing ligand death pathway-mediated human beta-cell destruction". Diabetologia. 45 (12): 1678–88. doi:10.1007/s00125-002-0926-2
Decoy receptor 1 (978 words) [view diff] no match in snippet view article find links to article
"TNF-related apoptosis-inducing ligand death pathway-mediated human beta-cell destruction". Diabetologia. 45 (12): 1678–88. doi:10.1007/s00125-002-0926-2
NKX2-2 (622 words) [view diff] no match in snippet view article find links to article
Beau MM, Davis EM, Ogata M, Iwamoto Y, German MS, Bell GI (Aug 1998). "Beta-cell transcription factors and diabetes: mutations in the coding region of
SOX13 (1,012 words) [view diff] exact match in snippet view article find links to article
Shtauvere-Brameus A, Hagopian W, Rumba I, Sanjeevi CB (Apr 2002). "Antibodies to new beta cell antigen ICA12 in Latvian diabetes patients". Annals of the New York Academy
ATP2B4 (1,159 words) [view diff] no match in snippet view article find links to article
Ca2+-ATPase isoforms is expressed in islets of Langerhans and pancreatic beta-cell lines". The Biochemical Journal. 314 ( Pt 2) (Pt 2): 663–9. doi:10.1042/bj3140663
Lamin B1 (942 words) [view diff] exact match in snippet view article find links to article
"Evidence for the carboxyl methylation of nuclear lamin-B in the pancreatic beta cell". Biochem. Biophys. Res. Commun. 268 (2): 249–54. doi:10.1006/bbrc.2000
Preproinsulin (150 words) [view diff] case mismatch in snippet view article find links to article
stable ER intermediate. Proprotein convertase 1, proprotein convertase 2 preproinsulin definition in the glossary of the Beta Cell Biology Consortium
National Centre for Cell Science (172 words) [view diff] no match in snippet view article find links to article
"Pyridoxal 5′ phosphate protects islets against streptozotocin-induced beta-cell dysfunction – in vitro and in vivo". Ebm.rsmjournals.com. 2011-04-01.
Prolactin receptor (959 words) [view diff] exact match in snippet view article find links to article
Freemark M (August 2014). "Knockdown of prolactin receptors in a pancreatic beta cell line: effects on DNA synthesis, apoptosis, and gene expression". primary
SERPINB10 (580 words) [view diff] exact match in snippet view article find links to article
Eriksson JW, Johansson L, Danielsson A (May 2012). "Novel pancreatic beta cell-specific proteins: antibody-based proteomics for identification of new
MAF (gene) (1,262 words) [view diff] no match in snippet view article
PMID 2554284. Olbrot M, Rud J, Moss LG, Sharma A (May 2002). "Identification of beta-cell-specific insulin gene transcription factor RIPE3b1 as mammalian MafA"
Endoribonuclease-prepared siRNA (650 words) [view diff] exact match in snippet view article find links to article
S2CID 8554458. Konstantinova; et al. (2007). "EphA-Ephrin-A-mediated beta cell communication regulates insulin secretion from pancreatic islets". Cell
HNF1B (1,238 words) [view diff] no match in snippet view article find links to article
HNF-1 (DcoH / PCBD) genes in relation to type 2 diabetes mellitus and beta-cell function". Hum. Mutat. 18 (4): 356–7. doi:10.1002/humu.1201. PMID 11668623
MAFB (gene) (1,471 words) [view diff] exact match in snippet view article
Cordes S, Sieweke M, Stein R (Mar 2007). "MafB is required for islet beta cell maturation". Proceedings of the National Academy of Sciences of the United
Insulin (medication) (9,706 words) [view diff] exact match in snippet view article
proper. They are either absorbed rapidly in an attempt to mimic real beta cell insulin (as with insulin lispro, insulin aspart, and insulin glulisine)
Glucose 6-phosphatase (2,301 words) [view diff] exact match in snippet view article find links to article
2005). "In islet-specific glucose-6-phosphatase-related protein, the beta cell antigenic sequence that is targeted in diabetes is not responsible for
Colin Nichols (780 words) [view diff] exact match in snippet view article find links to article
Herrera-Sosa, H.; Nguy, K.; Bryan, J.; Nelson, D. (1995). "Cloning of the beta cell high-affinity sulfonylurea receptor: A regulator of insulin secretion"
Protein kinase, AMP-activated, alpha 1 (1,181 words) [view diff] exact match in snippet view article find links to article
of AMP-activated protein kinase in the regulation by glucose of islet beta cell gene expression". Proc. Natl. Acad. Sci. U.S.A. 97 (8): 4023–8. Bibcode:2000PNAS
Electroporation (4,986 words) [view diff] no match in snippet view article find links to article
McClenaghan NH (May 2007). "Physiological regulation of the pancreatic {beta}-cell: functional insights for understanding and therapy of diabetes". Experimental
Malonyl-CoA decarboxylase (1,915 words) [view diff] no match in snippet view article find links to article
Lopaschuk GD, Prentki M (May 1999). "Cloning and expression of rat pancreatic beta-cell malonyl-CoA decarboxylase". The Biochemical Journal. 340 (1): 213–7. doi:10
Somatostatin (2,407 words) [view diff] exact match in snippet view article find links to article
release of pancreatic hormones Somatostatin release is triggered by the beta cell peptide urocortin3 (Ucn3) to inhibit insulin release. Inhibits the release
PRKAB1 (1,618 words) [view diff] exact match in snippet view article find links to article
of AMP-activated protein kinase in the regulation by glucose of islet beta cell gene expression". Proc. Natl. Acad. Sci. U.S.A. 97 (8): 4023–8. Bibcode:2000PNAS
Genipin (232 words) [view diff] exact match in snippet view article find links to article
UCP2-mediated proton leak and acutely reverses obesity- and high glucose-induced beta cell dysfunction in isolated pancreatic islets". Cell Metabolism. 3 (6): 417–27
Muscarinic acetylcholine receptor M3 (1,654 words) [view diff] no match in snippet view article find links to article
Mears D, Lu H, Deng C, Heard T, Wess J (June 2006). "A critical role for [beta] cell M3 muscarinic acetylcholine receptors in regulating insulin release and
EXTL3 (571 words) [view diff] no match in snippet view article find links to article
"Identification of a receptor for reg (regenerating gene) protein, a pancreatic beta-cell regeneration factor". J. Biol. Chem. 275 (15): 10723–6. doi:10.1074/jbc
Ubiquitin carboxy-terminal hydrolase L1 (2,614 words) [view diff] exact match in snippet view article find links to article
2012). "Ubiquitin C-terminal hydrolase L1 is required for pancreatic beta cell survival and function in lipotoxic conditions". Diabetologia. 55 (1):
Mir-375 (1,050 words) [view diff] no match in snippet view article find links to article
pancreatic tissue microRNA-375 associates with human type 2 diabetes through beta-cell deficit and islet amyloid deposition". Pancreas. 39 (6): 843–846. doi:10
Phosphatidylinositol 4,5-bisphosphate (1,829 words) [view diff] exact match in snippet view article find links to article
in chromaffin cell and in central nerve system , PIPKIγ knockdown in beta cell lines , and over-expression of membrane-tethered inositol 5-phosphatase
Nestin (protein) (1,873 words) [view diff] no match in snippet view article
K, Ball SG, Turnpenny LW, Brickwood S, Wilson DI, Hanley NA (2002). "Beta-cell differentiation during human development does not rely on nestin-positive
Histidine kinase (2,099 words) [view diff] exact match in snippet view article find links to article
and characterization of a novel protein histidine kinase in the islet beta cell: evidence for its regulation by mastoparan, an activator of G-proteins
Phospholipid scramblase (1,682 words) [view diff] no match in snippet view article find links to article
2002). "Identifying the links between obesity, insulin resistance and beta-cell function: potential role of adipocyte-derived cytokines in the pathogenesis
Ontology for Biomedical Investigations (907 words) [view diff] case mismatch in snippet view article find links to article
Stoeckert Jr CJ (7 July 2013). "Development of an Application Ontology for Beta Cell Genomics Based On the Ontology for Biomedical Investigations" (PDF). ICBO:
Connexin (2,441 words) [view diff] exact match in snippet view article find links to article
murine Cx29. Not known to form gap junctions. Cx36 GJD2/GJA9 Pancreatic beta cell function, mediating the release of insulin. Neurons throughout the central
Sweetness (3,796 words) [view diff] no match in snippet view article find links to article
Vennekens, Rudi (31 March 2017). "Steviol glycosides enhance pancreatic beta-cell function and taste sensation by potentiation of TRPM5 channel activity"
Potassium channel blocker (2,643 words) [view diff] no match in snippet view article find links to article
J (February 2007). "Gating modifier peptides as probes of pancreatic beta-cell physiology". Toxicon. 49 (2): 231–8. doi:10.1016/j.toxicon.2006.09.012
RAB27A (1,544 words) [view diff] no match in snippet view article find links to article
insulin-containing secretory granules and is essential for pancreatic beta-cell exocytosis". Mol. Endocrinol. 18 (1): 117–26. doi:10.1210/me.2003-0300
BAT2 (1,002 words) [view diff] no match in snippet view article find links to article
possibly thought to be involved with the inflammatory process of pancreatic beta-cell destruction during the development of IDDM. This gene is also a candidate
MTORC2 (3,312 words) [view diff] exact match in snippet view article find links to article
tissue. Loss of mTORC2/Rictor in pancreatic beta cells results in reduced beta cell mass and insulin secretion, and hyperglycemia and glucose intolerance
Neuroscience Information Framework (1,386 words) [view diff] case mismatch in snippet view article find links to article
Software resource, Data repository Biocompare Database, Antibody supplier Beta Cell Biology Consortium Database, Reagent supplier BAMS Nested Regions Database
Vesicular monoamine transporter 2 (1,848 words) [view diff] no match in snippet view article find links to article
(2008). "VMAT2 gene expression and function as it applies to imaging beta-cell mass". J. Mol. Med. 86 (1): 5–16. doi:10.1007/s00109-007-0242-x. PMID 17665159
Stevia (3,877 words) [view diff] no match in snippet view article find links to article
Kerselaers, S.; et al. (31 March 2017). "Steviol glycosides enhance pancreatic beta-cell function and taste sensation by potentiation of TRPM5 channel activity"
Exenatide (1,961 words) [view diff] no match in snippet view article find links to article
Yki-Järvinen H, Heine RJ (May 2009). "One-year treatment with exenatide improves beta-cell function, compared with insulin glargine, in metformin-treated type 2
TXNIP (988 words) [view diff] no match in snippet view article find links to article
stimulated by glucose through a carbohydrate response element and induces beta-cell apoptosis". Endocrinology. 146 (5): 2397–405. doi:10.1210/en.2004-1378
AKT1 (2,852 words) [view diff] no match in snippet view article find links to article
286.18.2308. PMID 11710897. Dickson LM, Rhodes CJ (2004). "Pancreatic beta-cell growth and survival in the onset of type 2 diabetes: a role for protein
PTPRT (2,596 words) [view diff] exact match in snippet view article find links to article
dephosphorylate E-cadherin and p120catenin co-immunoprecipitated from a pancreatic beta cell line, MIN6-m9. This suggests that these proteins are PTPrho substrates
Autoimmunity (5,474 words) [view diff] exact match in snippet view article find links to article
antioxidant vitamins and trace elements during pregnancy and risk of advanced beta cell autoimmunity in the child". The American Journal of Clinical Nutrition
Branched-chain amino acid (3,260 words) [view diff] exact match in snippet view article find links to article
In addition to cell signaling, the mTOR pathway also plays a role in beta cell growth leading to insulin secretion. High glucose in the blood begins
Mark Atkinson (scientist) (2,160 words) [view diff] exact match in snippet view article
role of environment in the initiation of type 1 diabetes, stem cells and beta cell regeneration, pancreatic pathology, clinical trials seeking to prevent
Nephrin (1,349 words) [view diff] no match in snippet view article find links to article
(2015). "Nephrin, a transmembrane protein, is involved in pancreatic beta-cell survival signaling". Mol. Cell. Endocrinol. 400: 112–28. doi:10.1016/j
International Classification of Diseases for Oncology (9,855 words) [view diff] exact match in snippet view article find links to article
adenocarcinoma (M8151/0) Insulinoma, NOS (C25._) Beta cell adenoma M8151/3 Insulinoma, malignant (C25._) Beta cell tumor, malignant (M8152/0) Glucagonoma, NOS
Cav1.3 (3,298 words) [view diff] exact match in snippet view article find links to article
for the L-type Ca(2+) channel alpha(1D) subunit in postnatal pancreatic beta cell generation". The Journal of Clinical Investigation. 108 (7): 1015–22.
Ghrelin (4,139 words) [view diff] no match in snippet view article find links to article
Solimena M (May 2008). "Pancreas islets in metabolic signaling--focus on the beta-cell". Frontiers in Bioscience. 13 (13): 7156–71. doi:10.2741/3218. PMID 18508724
Peroxisome proliferator-activated receptor gamma (3,555 words) [view diff] no match in snippet view article find links to article
Abdul-Ghani MA, Tripathy D, DeFronzo RA (May 2006). "Contributions of beta-cell dysfunction and insulin resistance to the pathogenesis of impaired glucose
Transplantable organs and tissues (2,723 words) [view diff] exact match in snippet view article find links to article
cells to be blocked at S phase, which induces apoptosis. This loss of beta cell mass eventually leads to a loss of most of the transplanted beta cells
Ion channel (5,012 words) [view diff] no match in snippet view article find links to article
epithelial transport of nutrients and ions, T-cell activation and pancreatic beta-cell insulin release. In the search for new drugs, ion channels are a frequent
UNC13B (1,178 words) [view diff] no match in snippet view article find links to article
insulin-containing secretory granules and is essential for pancreatic beta-cell exocytosis". Mol. Endocrinol. 18 (1): 117–26. doi:10.1210/me.2003-0300
Latent autoimmune diabetes in adults (2,786 words) [view diff] exact match in snippet view article find links to article
medications) as type 2 diabetes, it will not halt or slow the progression of beta cell destruction, and people with LADA will eventually become insulin-dependent
Sathyanarayana Srikanta (347 words) [view diff] case mismatch in snippet view article find links to article
Institute of Medical Sciences, Harvard Medical School Known for Islet Beta Cell, Endocrinology, Diabetes Scientific career Institutions Harvard Medical
Alex McDowell (1,980 words) [view diff] case mismatch in snippet view article find links to article
immersive virtual reality experience of the interior of a single Pancreatic Beta Cell. In a funded partnership with the USC Bridge Institute, the project aims
BCCIP (973 words) [view diff] no match in snippet view article find links to article
Shen Z (2004). "Inhibition of G1 to S cell cycle progression by BCCIP beta". Cell Cycle. 3 (3): 343–8. doi:10.4161/cc.3.3.672. PMID 14726710. Deloukas
Transcription factor (7,650 words) [view diff] no match in snippet view article find links to article
HNF1beta, HNF1alpha, and HNF4alpha in regulating pancreas development, beta-cell function and growth. Endocrine Development. 12. pp. 33–45. doi:10.1159/000109603
Cell isolation (1,513 words) [view diff] no match in snippet view article find links to article
Kieffer TJ, Woltjen K, Osafune K, Yabe D, Inagaki N (October 2017). "Beta-cell replacement strategies for diabetes". Journal of Diabetes Investigation
Wnt signaling pathway (7,083 words) [view diff] no match in snippet view article find links to article
Welters HJ, Kulkarni RN (December 2008). "Wnt signaling: relevance to beta-cell biology and diabetes". Trends in Endocrinology and Metabolism. 19 (10):
Amyloid (5,975 words) [view diff] no match in snippet view article find links to article
induce anti-toxic oligomer antibodies does not prevent h-IAPP-induced beta-cell apoptosis in h-IAPP transgenic mice". Diabetes. 56 (5): 1324–32. doi:10
Insulin pump (4,300 words) [view diff] exact match in snippet view article find links to article
insulin requirements and require an adjustment to the basal rate: continued beta cell death following diagnosis of type 1 diabetes (honeymoon period) growth
List of diseases (P) (1,912 words) [view diff] exact match in snippet view article
syndrome Pancreas agenesis Pancreas divisum Pancreatic adenoma Pancreatic beta cell agenesis with neonatal diabetes mellitus Pancreatic cancer Pancreatic
NME4 (1,012 words) [view diff] exact match in snippet view article find links to article
mitochondrial isoform of the nucleoside diphosphate kinase in the pancreatic beta cell: evidence for its complexation with mitochondrial succinyl-CoA synthetase"
Gestational diabetes (8,777 words) [view diff] no match in snippet view article find links to article
Brelje TC (June 1997). "Adaptation of islets of Langerhans to pregnancy: beta-cell growth, enhanced insulin secretion and the role of lactogenic hormones"
Progesterone (9,387 words) [view diff] no match in snippet view article find links to article
receptor knockout mice have an improved glucose homeostasis secondary to beta -cell proliferation". Proceedings of the National Academy of Sciences of the
IMOD (software) (1,038 words) [view diff] exact match in snippet view article
(2001). "Organellar relationships in the Golgi region of the pancreatic beta cell line, HIT-T15, visualized by high resolution electron tomography". Proceedings
REG1A (1,296 words) [view diff] no match in snippet view article find links to article
PMID 8020983. Otonkoski T, Mally MI, Hayek A (1994). "Opposite effects of beta-cell differentiation and growth on reg expression in human fetal pancreatic
Transient receptor potential channel (5,479 words) [view diff] no match in snippet view article find links to article
Voets T, Vennekens R (March 2017). "Steviol glycosides enhance pancreatic beta-cell function and taste sensation by potentiation of TRPM5 channel activity"
Gene–environment interaction (4,316 words) [view diff] exact match in snippet view article find links to article
total cholesterol), glycemic traits (plasma glucose and insulin, HOMA-IR, beta cell function as HOMA-BC), obesity anthropometrics (BMI/obesity, adiposity
GDF11 (3,794 words) [view diff] no match in snippet view article find links to article
2004). "GDF11 modulates NGN3+ islet progenitor cell number and promotes beta-cell differentiation in pancreas development". Development. 131 (24): 6163–74
CDKAL1 (1,117 words) [view diff] no match in snippet view article find links to article
diabetes genes CDKAL1 and HHEX/IDE are associated with decreased pancreatic beta-cell function". Diabetes. 56 (12): 3101–4. doi:10.2337/db07-0634. PMID 17804762
Statin (11,570 words) [view diff] exact match in snippet view article find links to article
prenylation in glucose-induced insulin secretion from the pancreatic islet beta cell: a perspective". Journal of Cellular and Molecular Medicine. 12 (1): 164–73
James Shapiro (physician) (1,381 words) [view diff] exact match in snippet view article
chapters, as well as being Co-Editor of a book on islet transplantation and beta cell replacement therapy. 1988 Anthony Wood Memorial Prize (Clinical Oncology)
MicroRNA 375 (677 words) [view diff] no match in snippet view article find links to article
pancreatic tissue microRNA-375 associates with human type 2 diabetes through beta-cell deficit and islet amyloid deposition". Pancreas. 39 (6): 843–6. doi:10
PLA2G6 (2,094 words) [view diff] no match in snippet view article find links to article
PMID 14634037. Bao S, Jin C, Zhang S, Turk J, Ma Z, Ramanadham S (Feb 2004). "Beta-cell calcium-independent group VIA phospholipase A(2) (iPLA(2)beta): tracking
C19orf18 (975 words) [view diff] exact match in snippet view article find links to article
Nedd4 family interacting protein 1 (NDFIP1) which promotes pancreatic beta cell death reduces insulin secretion. Activin A receptor type 2A (ACVR2A) is
MTOR (12,966 words) [view diff] no match in snippet view article find links to article
2011). "Rictor/mTORC2 is essential for maintaining a balance between beta-cell proliferation and cell size". Diabetes. 60 (3): 827–37. doi:10.2337/db10-1194
Rebecca Hasson (1,007 words) [view diff] no match in snippet view article find links to article
Weigensberg, M.I. Goran (2010). Cortisol is negatively associated with beta-cell capacity and acute insulin response to glucose in Latino youth. Journal
National Institute of Nutrition, Hyderabad (2,212 words) [view diff] no match in snippet view article find links to article
"Pyridoxal 5' phosphate protects islets against streptozotocin-induced beta-cell dysfunction – in vitro and in vivo". Ebm.rsmjournals.com. 4 April 2011
Obesogen (6,457 words) [view diff] no match in snippet view article find links to article
peptide and improves abnormal glucose tolerance in minipigs with reduced beta-cell mass". Exp. Diabetes Res. 4 (2): 93–105. doi:10.1155/EDR.2003.93. PMC 2478600
Roy Taylor (scientist) (743 words) [view diff] exact match in snippet view article
R. (1 November 2011). "Reversal of type 2 diabetes: normalisation of beta cell function in association with decreased pancreas and liver triacylglycerol"
GroEL (5,384 words) [view diff] no match in snippet view article find links to article
"Immunocytochemical localization of heat-shock protein 60-related protein in beta-cell secretory granules and its altered distribution in non-obese diabetic
Neonatal hypoglycemia (1,777 words) [view diff] no match in snippet view article find links to article
diabetes. Congenital hyperinsulinism is correlated with the abnormality of beta-cell regulation within the pancreas. Isolated islet adenoma, which is a focal
Equine metabolic syndrome (2,838 words) [view diff] exact match in snippet view article find links to article
Boston, RC (December 2009). "Type 2 diabetes mellitus with pancreatic beta cell dysfunction in 3 horses confirmed with minimal model analysis". Equine
Humanin (1,825 words) [view diff] no match in snippet view article find links to article
Cohen P, Lee KW (March 2010). "The neurosurvival factor Humanin inhibits beta-cell apoptosis via signal transducer and activator of transcription 3 activation
HLA-DQ2 (3,376 words) [view diff] exact match in snippet view article find links to article
Groop L, Sundkvist G (2006). "HLA-DQB1 genotypes, islet antibodies and beta cell function in the classification of recent-onset diabetes among young adults
Adiposopathy (3,732 words) [view diff] exact match in snippet view article find links to article
hormone, genetic syndromes of insulin resistance, and decreased pancreatic beta cell function due to genetic syndromes or surgical excision. High blood pressure
Major facilitator superfamily (5,021 words) [view diff] exact match in snippet view article find links to article
beta cells; may comprise part of the glucose-sensing mechanism of the beta cell. May also participate with the Na(+)/glucose cotransporter in the transcellular
Peptide therapeutics (2,722 words) [view diff] exact match in snippet view article find links to article
PMID 16505481. Thorens B (September 1992). "Expression cloning of the pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1". Proceedings
Diacylglycerol kinase beta (1,451 words) [view diff] exact match in snippet view article find links to article
GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people". Diabetologia. 53 (8): 1647–55
Ohad Birk (3,262 words) [view diff] no match in snippet view article find links to article
R. (1996-04-01). "NOD mouse diabetes: the ubiquitous mouse hsp60 is a beta-cell target antigen of autoimmune T cells". Journal of Autoimmunity. 9 (2):
Cell encapsulation (8,744 words) [view diff] no match in snippet view article find links to article
2006). "Morphological and functional characterization of a pancreatic beta-cell line microencapsulated in sodium cellulose sulfate/poly(diallyldimethylammonium
Infections associated with diseases (5,369 words) [view diff] exact match in snippet view article find links to article
One study found Coxsackie B1 virus associated with a higher risk of the beta cell autoimmunity that portends type 1 diabetes; though Coxsackie B3 and B6