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searching for Kir6.2 10 found (19 total)

alternate case: kir6.2

Permanent neonatal diabetes (412 words) [view diff] exact match in snippet view article find links to article

caused by activating mutations of the KCNJ11 gene, which codes for the Kir6.2 subunit of the beta cell KATP channel. This disease is considered to be
HMR 1883 (901 words) [view diff] exact match in snippet view article find links to article
selectively the Kir6.2/SUR2A KATP subtype, found mostly in the membranes of cardiac cells. However, data showing that HMR 1098 inhibits the Kir6.2/SUR1 KATP
Hyperinsulinemic hypoglycemia (1,114 words) [view diff] exact match in snippet view article find links to article
11p15 Paternal Kir6.2 mutation with clonal loss of heterozygosity of 11p15 Diffuse hyperinsulinism KATP channel disorders SUR1 mutations Kir6.2 mutations Glucokinase
Plakophilin-2 (3,982 words) [view diff] exact match in snippet view article find links to article
has also shown that plakophilin-2 binds to the K(ATP) channel subunit, Kir6.2, and that in cardiomyocytes from haploinsufficient PKP2 mice, K(ATP) channel
ABCC8 (1,238 words) [view diff] exact match in snippet view article find links to article
"Mutations in the genes encoding the pancreatic beta-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) in diabetes mellitus and hyperinsulinism". Human
Cyclin D/Cdk4 (2,799 words) [view diff] exact match in snippet view article find links to article
Kir6.2, a subunit of the ATP-sensitive K channel that regulates glucose-induced insulin secretion. When the CyclinD/Cdk4 complex is inhibited, Kir6.2
Glutamate dehydrogenase 1 (3,043 words) [view diff] exact match in snippet view article find links to article
ABCC8, which encodes the protein SUR1, or KCNJ11, which encodes the protein Kir6.2. In the Ashkenazi Jewish population, two ABCC8 founder mutations are responsible
Ankyrin-2 (3,706 words) [view diff] exact match in snippet view article find links to article
Hund TJ, Anderson ME, Mohler PJ (10 September 2010). "Ankyrin-B regulates Kir6.2 membrane expression and function in heart". The Journal of Biological Chemistry
Genetic causes of type 2 diabetes (2,331 words) [view diff] exact match in snippet view article find links to article
subfamily J, member 11), encodes the islet ATP-sensitive potassium channel Kir6.2, and TCF7L2 (transcription factor 7–like 2) regulates proglucagon gene expression
Developmental bioelectricity (17,264 words) [view diff] exact match in snippet view article find links to article
Mutations in the Gene Encoding the ATP-Sensitive Potassium-Channel Subunit Kir6.2 and Permanent Neonatal Diabetes" (PDF). New England Journal of Medicine