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searching for Promoter activity 169 found (172 total)

CD58 (2,682 words) [view diff] exact match in snippet view article find links to article

sclerosis, has enhancer properties and can significantly boost the CD58 promoter activity in lymphoblast cells. The protective (C) rs1335532 allele creates

Duodenal cytochrome B (643 words) [view diff] exact match in snippet view article find links to article

the DCYTB promoter (SNP rs884409) which reduced functional DCYTB promoter activity was also associated with reduced serum ferritin levels in a patient

ALOX15 (5,728 words) [view diff] exact match in snippet view article find links to article

resulting from the expression of its mutant forms, regulates ALOX15 promoter activity in human and in mouse, albeit in directionally opposite manners. These

GUS reporter system (1,121 words) [view diff] exact match in snippet view article find links to article

actively expressed. In this way, strong promoter activity produces much staining and weak promoter activity produces less staining. The uidA gene can

SURF2 (173 words) [view diff] exact match in snippet view article find links to article

bidirectional promoter with SURF1 on the opposite strand. A bidirectional promoter activity is expected in the intergenic region between SURF1 and SURF2, as seen

Mammalian promoter database (443 words) [view diff] exact match in snippet view article find links to article

for eukaryotic organisms are provided by an EPD database; however, promoter activity information at tissue/ cell centric level is not offered. The MPromDb

YY1 (1,925 words) [view diff] exact match in snippet view article find links to article

distal segment results in differential regulation of human vegfa promoter activity during angiogenesis". Nucleic Acids Research. 45 (5): 2423–2437. doi:10

MEF2C (1,887 words) [view diff] exact match in snippet view article find links to article

risk of multiple sclerosis, and responsible for reduced CXCR5 gene promoter activity in B-cells during activation, that could lead to decreased autoimmune

CXCR5 (1,956 words) [view diff] exact match in snippet view article find links to article

for appearance of MEF2C-binding site resulted in reduced CXCR5 gene promoter activity in B-cells during activation, that could lead to decreased autoimmune

TATA box (4,785 words) [view diff] exact match in snippet view article find links to article

long-range regulatory elements that increase promoter activity while silencers repress promoter activity. Mutations to the TATA box can range from a deletion

EEF1A2 (983 words) [view diff] exact match in snippet view article find links to article

(EEF1A2): complete sequence and characterization of gene structure and promoter activity". Genomics. 68 (1): 63–70. doi:10.1006/geno.2000.6271. PMID 10950927

SNRK (545 words) [view diff] exact match in snippet view article find links to article

Iacobelli M, Wachsman W, McGuire KL (July 2000). "Repression of IL-2 promoter activity by the novel basic leucine zipper p21SNFT protein". Journal of Immunology

POU4F3 (561 words) [view diff] exact match in snippet view article find links to article

Davis-Silberman N, et al. (2004). "Brn-3c (POU4F3) regulates BDNF and NT-3 promoter activity". Biochem. Biophys. Res. Commun. 324 (1): 372–81. doi:10.1016/j.bbrc

ATP1A4 (937 words) [view diff] exact match in snippet view article find links to article

Blanco G (2006). "The transcription factor CREMtau and cAMP regulate promoter activity of the Na, K-ATPase alpha4 isoform". Mol. Reprod. Dev. 73 (11): 1435–47

Sodium-dependent phosphate transport protein 1 (456 words) [view diff] exact match in snippet view article find links to article

and human type I Na-phosphate cotransporter genes: structure and promoter activity". Am. J. Physiol. Renal Physiol. 281 (6): F1082–91. doi:10.1152/ajprenal

Choline transporter-like protein 1 (742 words) [view diff] exact match in snippet view article find links to article

Tie A, Tarnopolsky M, Bakovic M (June 2006). "Genomic organization, promoter activity, and expression of the human choline transporter-like protein 1" (PDF)

Forkhead box protein O1 (3,343 words) [view diff] exact match in snippet view article find links to article

to induce expression of p27KIP1, repress cyclin D1 and cyclin D2 promoter activity and encourages cell cycle arrest at cyclin G1 (CCNG1). As a result

SNW1 (1,441 words) [view diff] exact match in snippet view article find links to article

in Notch intracellular domains is critical for regulation of HES promoter activity". Mechanisms of Development. 104 (1–2): 3–20. doi:10.1016/s0925-4773(01)00373-2

Sodium-dependent multivitamin transporter (777 words) [view diff] exact match in snippet view article find links to article

biotin transporter hSMVT promoter by KLF-4 and AP-2: confirmation of promoter activity in vivo". American Journal of Physiology. Cell Physiology. 292 (4):

ZNF148 (1,032 words) [view diff] exact match in snippet view article find links to article

Whatling C, Watkins H, Henney A (May 1999). "Human stromelysin gene promoter activity is modulated by transcription factor ZBP-89". FEBS Letters. 450 (3):

Integrin alpha X (992 words) [view diff] exact match in snippet view article find links to article

S2CID 24550506. Córbi AL, Lopéz-Rodríguez C (1997). "CD11c integrin gene promoter activity during myeloid differentiation". Leuk. Lymphoma. 25 (5–6): 415–25

ALX4 (1,078 words) [view diff] exact match in snippet view article find links to article

Hamel PA (January 2002). "Alx4 binding to LEF-1 regulates N-CAM promoter activity". The Journal of Biological Chemistry. 277 (2): 1120–7. doi:10.1074/jbc

Heparanase (1,802 words) [view diff] exact match in snippet view article find links to article

promoter: role of GA-binding protein and Sp1 in regulating HPR1 basal promoter activity". J. Biol. Chem. 277 (11): 8989–98. doi:10.1074/jbc.M105682200. PMID 11779847

N-myc-interactor (1,163 words) [view diff] exact match in snippet view article find links to article

c-Myc-induced human telomerase reverse transcriptase gene (hTERT) promoter activity in breast cancer". J. Biol. Chem. 277 (23): 20965–73. doi:10.1074/jbc

Collagen, type XI, alpha 1 (1,082 words) [view diff] exact match in snippet view article find links to article

transcription factor CCAAT-binding factor CBF/NF-Y regulates the proximal promoter activity in the human alpha 1(XI) collagen gene (COL11A1)". J. Biol. Chem.

Zinc finger protein 804A (1,019 words) [view diff] exact match in snippet view article find links to article

Han Chinese patients, and that the rs359895 allele increases the promoter activity of ZNF804A. The results of another study suggest that there is no

NFATC3 (1,045 words) [view diff] exact match in snippet view article find links to article

"Human immunodeficiency virus type-1 tat enhances interleukin-2 promoter activity through synergism with phorbol ester and calcium-mediated activation

NFATC4 (956 words) [view diff] exact match in snippet view article find links to article

"Human immunodeficiency virus type-1 tat enhances interleukin-2 promoter activity through synergism with phorbol ester and calcium-mediated activation

NRL (gene) (1,095 words) [view diff] exact match in snippet view article

(Nov 1996). "The bZIP transcription factor Nrl stimulates rhodopsin promoter activity in primary retinal cell cultures". The Journal of Biological Chemistry

DLX4 (1,079 words) [view diff] exact match in snippet view article find links to article

(2004). "Inhibition of beta protein 1 expression enhances beta-globin promoter activity and beta-globin mRNA levels in the human erythroleukemia (K562) cell

Pyruvate kinase PKLR (912 words) [view diff] exact match in snippet view article find links to article

analysis of human pyruvate kinase L-gene and identification of the promoter activity in erythroid cells". Biochem. Biophys. Res. Commun. 188 (2): 516–23

CEBPD (1,235 words) [view diff] exact match in snippet view article find links to article

Deng WG, Wu KK (Mar 2002). "Dynamic regulation of cyclooxygenase-2 promoter activity by isoforms of CCAAT/enhancer-binding proteins". The Journal of Biological

Solute carrier organic anion transporter family member 2A1 (682 words) [view diff] exact match in snippet view article find links to article

for the human prostaglandin transporter hPGT: gene organization, promoter activity, and chromosomal localization". Biochemical and Biophysical Research

Collagen, type XII, alpha 1 (944 words) [view diff] no match in snippet view article find links to article

M (October 1998). "The chick and human collagen alpha1(XII) gene promoter--activity of highly conserved regions around the first exon and in the first

Translationally controlled tumor protein (3,584 words) [view diff] exact match in snippet view article find links to article

well-conserved in mammals. The assay with reporter gene exhibits a strong promoter activity comparable to viral promoters. TCTP protein is also known as p23,

Epstein–Barr virus latent membrane protein 2 (1,133 words) [view diff] exact match in snippet view article find links to article

widely and unpredictably suggesting little co-ordinate control of promoter activity or mRNA abundance. Residues 497 (LMP2A) and 378 (LMP2B) are encoded

Estrogen-related receptor beta (800 words) [view diff] exact match in snippet view article find links to article

et al. (August 2004). "Differential and opposing regulation of PAI-1 promoter activity by estrogen receptor alpha and estrogen receptor beta in endothelial

USF1 (4,538 words) [view diff] exact match in snippet view article find links to article

Overexpression of either USF1 or USF2 is found to elevate the TFGB1 promoter activity in human embryonic kidney cells. However, only USF1 overexpression

SON (gene) (2,301 words) [view diff] exact match in snippet view article

hepatitis B virus (HBV). Through this binding, it represses HBV core promoter activity, transcription of HBV genes, and production of HBV virions. The protein

ELK1 (2,465 words) [view diff] exact match in snippet view article find links to article

its growth control pathway. Recent literature reveals that c-fos promoter activity is inhibited, while overexpression of BRCA1a/1b reduces MEK-induced

NFATC1 (1,107 words) [view diff] exact match in snippet view article find links to article

"Human immunodeficiency virus type-1 tat enhances interleukin-2 promoter activity through synergism with phorbol ester and calcium-mediated activation

TFAP2B (1,143 words) [view diff] exact match in snippet view article find links to article

"Tumor-specific activation of human telomerase reverses transcriptase promoter activity by activating enhancer-binding protein-2beta in human lung cancer

Interleukin 16 (1,487 words) [view diff] exact match in snippet view article find links to article

Kornfeld H, Viglianti GA (January 1997). "IL-16 represses HIV-1 promoter activity". Journal of Immunology. 158 (1): 5–8. doi:10.4049/jimmunol.158.1

Spermidine (1,400 words) [view diff] exact match in snippet view article find links to article

cell-associated keratins K15 and K19, and dose-dependently modulated K15 promoter activity in situ and the colony forming efficiency, proliferation and K15 expression

IGFBP1 (1,045 words) [view diff] exact match in snippet view article find links to article

human gene for insulin-like growth factor binding protein-1. Basal promoter activity in HEP G2 cells depends upon liver factor B1". J. Biol. Chem. 265

IRF7 (1,417 words) [view diff] exact match in snippet view article find links to article

Yeow WS, Hageman N, Pitha PM (October 2000). "Regulation of the promoter activity of interferon regulatory factor-7 gene. Activation by interferon and

NFATC2 (1,445 words) [view diff] exact match in snippet view article find links to article

"Human immunodeficiency virus type-1 tat enhances interleukin-2 promoter activity through synergism with phorbol ester and calcium-mediated activation

FOXA2 (1,552 words) [view diff] exact match in snippet view article find links to article

Quian XB, Clevidence D, Costa RH (February 1992). "The restricted promoter activity of the liver transcription factor hepatocyte nuclear factor 3 beta

GTF2I (1,672 words) [view diff] exact match in snippet view article find links to article

Cheriyath V, Novina CD, Roy AL (Aug 1998). "TFII-I regulates Vbeta promoter activity through an initiator element". Molecular and Cellular Biology. 18

Lymphotoxin beta receptor (1,508 words) [view diff] exact match in snippet view article find links to article

interleukin 8. Overexpression of LTBR in HEK293 cells increases IL-8 promoter activity and leads to IL-8 release. LTBR is also essential for development

MCM6 (1,681 words) [view diff] exact match in snippet view article find links to article

(September 2003). "Lactase persistence DNA variant enhances lactase promoter activity in vitro: functional role as a cis regulatory element". Hum. Mol.

Y box binding protein 1 (1,450 words) [view diff] exact match in snippet view article find links to article

human immunodeficiency virus type 1 Tat and TAR RNA modulates viral promoter activity". J. Gen. Virol. 80. ( Pt 10) (10): 2629–38. doi:10.1099/0022-1317-80-10-2629

Prostacyclin synthase (1,212 words) [view diff] exact match in snippet view article find links to article

synthase (PTGIS): genomic organization, chromosomal localization, and promoter activity". Genomics. 36 (2): 296–304. doi:10.1006/geno.1996.0465. PMID 8812456

NOTCH3 (1,369 words) [view diff] exact match in snippet view article find links to article

in Notch intracellular domains is critical for regulation of HES promoter activity". Mech. Dev. 104 (1–2): 3–20. doi:10.1016/S0925-4773(01)00373-2. PMID 11404076

KLF11 (1,397 words) [view diff] exact match in snippet view article find links to article

(Jul 2007). "Human Krüppel-like factor 11 inhibits human proinsulin promoter activity in pancreatic beta cells". Diabetologia. 50 (7): 1433–41. doi:10

HHEX (1,530 words) [view diff] exact match in snippet view article find links to article

G (Apr 2003). "Thyroid-specific transcription factors control Hex promoter activity". Nucleic Acids Research. 31 (7): 1845–52. doi:10.1093/nar/gkg295

ABCB9 (866 words) [view diff] exact match in snippet view article find links to article

processing-like (TAPL, ABCB9): analysis of alternative splicing variants and promoter activity". Biochem. Biophys. Res. Commun. 309 (4): 815–22. doi:10.1016/j.bbrc

Basic helix-loop-helix ARNT-like protein 1 (5,652 words) [view diff] exact match in snippet view article find links to article

another study shows that the CLOCK/BMAL1 complex upregulates human LDLR promoter activity, suggesting the Arntl gene also plays a role in cholesterol homeostasis

Serum response factor (1,714 words) [view diff] exact match in snippet view article find links to article

(January 2021). "Reprogramming progressive cells display low CAG promoter activity". Stem Cells. 39 (1): 43–54. doi:10.1002/stem.3295. PMC 7821215. PMID 33075202

Deoxycytidine kinase (2,519 words) [view diff] exact match in snippet view article find links to article

between USF and Sp1 proteins regulate human deoxycytidine kinase promoter activity". The Journal of Biological Chemistry. 278 (50): 49901–10. doi:10

Reporter gene (1,980 words) [view diff] case mismatch in snippet view article find links to article

GUS/Luciferase Fusion Reporter for Plant Gene Trapping and for Assay of Promoter Activity with Luciferin-Dependent Control of the Reporter Protein Stability"

Liver X receptor alpha (1,641 words) [view diff] exact match in snippet view article find links to article

Cassel T, et al. (May 2002). "Different regulation of the LXRalpha promoter activity by isoforms of CCAAT/enhancer-binding proteins". Biochemical and Biophysical

RBPJ (1,484 words) [view diff] exact match in snippet view article find links to article

in Notch intracellular domains is critical for regulation of HES promoter activity". Mechanisms of Development. 104 (1–2): 3–20. doi:10.1016/s0925-4773(01)00373-2

KLF2 (2,219 words) [view diff] exact match in snippet view article find links to article

(peroxisome proliferator-activated receptor-γ) expression by inhibiting promoter activity. This prevents differentiation of preadipocytes into adipocytes, and

Sterol regulatory element-binding protein (2,125 words) [view diff] exact match in snippet view article find links to article

also inhibit the endogenous FGF21 transcription by reducing FGF21 promoter activity. SREBP-1c has also been shown to upregulate in a tissue specific manner

Lymphoid enhancer-binding factor 1 (1,797 words) [view diff] exact match in snippet view article find links to article

Hamel PA (January 2002). "Alx4 binding to LEF-1 regulates N-CAM promoter activity". The Journal of Biological Chemistry. 277 (2): 1120–1127. doi:10

Kruppel-like factors (2,233 words) [view diff] exact match in snippet view article find links to article

suppresses the p53 promoter and inhibits ornithine decarboxylase (ODC) promoter activity by competing with specificity protein-1 (Sp-1). Klf4 also interacts

Secretagogin (453 words) [view diff] exact match in snippet view article find links to article

et al. (2007). "Identification and characterization of secretagogin promoter activity". Scand. J. Immunol. 64 (6): 639–45. doi:10.1111/j.1365-3083.2006

P2RX1 (973 words) [view diff] exact match in snippet view article find links to article

Dhulipala PD, Lianos EA, Kotlikoff MI (2001). "Regulation of human P2X1 promoter activity by beta helix-loop-helix factors in smooth muscle cells". Gene. 269

Metallothionein 1G (644 words) [view diff] exact match in snippet view article find links to article

and expression of the human metallothionein-IG gene. Differential promoter activity of two linked metallothionein-I genes in response to heavy metals"

Neurofibromin 1 (5,725 words) [view diff] exact match in snippet view article find links to article

site must be intact for normal promoter activity to occur and methylation at the Sp1 sites may affect promoter activity. Proximal NF1 promoter/5' UTR methylation

KLF15 (2,804 words) [view diff] exact match in snippet view article find links to article

KLF15 in cultured hepatocytes increased both the expression and the promoter activity of the gene for phosphoenolpyruvate carboxykinase (PEPCK). KLF15 levels

Nuclear receptor 4A2 (2,159 words) [view diff] exact match in snippet view article find links to article

2003). "Orphan nuclear receptor Nurr1 directly transactivates the promoter activity of the tyrosine hydroxylase gene in a cell-specific manner". Journal

CHUK (2,736 words) [view diff] exact match in snippet view article find links to article

residue in the kinase domain, which correlated with derepression of EGF promoter activity and increased EGF expression, indicating that IKK-α stimulates migration

ID4 (3,046 words) [view diff] exact match in snippet view article find links to article

helix-loop-helix transcription factors in the regulation of the human Id4 gene promoter activity". Journal of Biological Chemistry. 273 (13): 7668–7674. doi:10.1074/jbc

TBX2 (2,749 words) [view diff] exact match in snippet view article find links to article

Tbx2 forms a complex with Nkx2.5 on the ANF gene to repress its promoter activity, so that the gene's expression is inhibited in the atrioventricular

PAX6 (2,710 words) [view diff] exact match in snippet view article find links to article

Anderson TR, Hedlund E, Carpenter EM (June 2002). "Differential Pax6 promoter activity and transcript expression during forebrain development". Mechanisms

GABA transporter type 1 (2,159 words) [view diff] exact match in snippet view article find links to article

creates an enhancer element and potentiates SLC6A1 GABA transporter promoter activity". Pharmacogenetics and Genomics. 19 (1): 53–65. doi:10.1097/FPC.0b013e328318b21a

STK11 (2,818 words) [view diff] exact match in snippet view article find links to article

interaction is decreased in the presence of estradiol. Moreover, STK11 promoter activity is significantly decreased in the presence of estradiol. The STK11/LKB1

Addgene (756 words) [view diff] exact match in snippet view article find links to article

shRNA knockdown, viral-mediated gene delivery, detection of miRNA and promoter activity. The plasmid collection includes: Genome engineering CRISPRs Transcription

LTBP3 (765 words) [view diff] exact match in snippet view article find links to article

Kantola AK, Keski-Oja J, Koli K (2006). "Induction of human LTBP-3 promoter activity by TGF-beta1 is mediated by Smad3/4 and AP-1 binding elements". Gene

Calcitonin gene-related peptide (3,045 words) [view diff] exact match in snippet view article find links to article

sumatriptan, increase intracellular calcium, which cause decreases in CGRP promoter activity. CGRP receptor is found in myelinated A-fibers axon which is required

CRYBB1 (1,110 words) [view diff] exact match in snippet view article find links to article

Luo YW, Chang BE (2006). "Recapitulation of human betaB1-crystallin promoter activity in transgenic zebrafish". Dev. Dyn. 235 (2): 435–43. doi:10.1002/dvdy

G6PC2 (776 words) [view diff] exact match in snippet view article find links to article

Mathews CE, Leiter EH, Hutton JC, O'Brien RM (Mar 1999). "Structure and promoter activity of an islet-specific glucose-6-phosphatase catalytic subunit-related

MT1F (818 words) [view diff] exact match in snippet view article find links to article

and expression of the human metallothionein-IG gene Differential promoter activity of two linked metallothionein-I genes in response to heavy metals"

APOBEC4 (365 words) [view diff] exact match in snippet view article find links to article

finding that A4 enhanced the replication of HIV-1 through boosting promoter activity, it also increased the expression of other relevant promoter mediated

CNOT2 (501 words) [view diff] exact match in snippet view article find links to article

Zwartjes CG, Jayne S, van den Berg DL, Timmers HT (2004). "Repression of promoter activity by CNOT2, a subunit of the transcription regulatory Ccr4-not complex"

Transcription factor Sp1 (3,446 words) [view diff] exact match in snippet view article find links to article

(October 1995). "Positive regulation of human alpha 1 (I) collagen promoter activity by transcription factor Sp1". Gene. 164 (2): 229–34. doi:10

Regulatory sequence (2,836 words) [view diff] exact match in snippet view article find links to article

Viales RR, Furlong EE (January 2018). "The degree of enhancer or promoter activity is reflected by the levels and directionality of eRNA transcription"

Neuroticism (5,411 words) [view diff] exact match in snippet view article find links to article

the long (l) variant of 5-HTTLPR, the short (s) variant has reduced promoter activity, and the first study on this subject has shown that the presence of

PPRC1 (689 words) [view diff] exact match in snippet view article find links to article

the peroxisome proliferator-activated receptor-gamma coactivator-1 promoter activity in a small heterodimer partner-dependent manner". Int. J. Mol. Med

TYRP1 (2,071 words) [view diff] exact match in snippet view article find links to article

region of the human tyrosinase-related protein gene enhances its promoter activity". Biochemical and Biophysical Research Communications. 184 (2): 568–575

PREB (431 words) [view diff] exact match in snippet view article find links to article

WD motif DNA-binding protein with a capacity to regulate prolactin promoter activity". Mol Endocrinol. 13 (4): 644–657. doi:10.1210/mend.13.4.0260. PMID 10194769

Cauliflower mosaic virus (2,789 words) [view diff] exact match in snippet view article find links to article

of inadvertently producing P6 domains, while still retaining full promoter activity. As one might expect, using shorter promoter lengths decreases the

ARAF (1,985 words) [view diff] exact match in snippet view article find links to article

Brennscheidt U, DeGennaro LJ, Rapp UR (1994). "The complete sequence and promoter activity of the human A-raf-1 gene (ARAF1)". Genomics. 20 (1): 43–55. doi:10

Notch 1 (1,497 words) [view diff] exact match in snippet view article find links to article

in Notch intracellular domains is critical for regulation of HES promoter activity". Mech. Dev. 104 (1–2): 3–20. doi:10.1016/s0925-4773(01)00373-2. PMID 11404076

Apolipoprotein AI (2,555 words) [view diff] exact match in snippet view article find links to article

unknown coactivators or corepressors, resulting in repression of APOA1 promoter activity. Simultaneously, Apo-AI production was increased by vitamin D antagonist

TCEAL1 (629 words) [view diff] exact match in snippet view article find links to article

1994). "Down-regulation of Rous sarcoma virus long terminal repeat promoter activity by a HeLa cell basic protein". Proc Natl Acad Sci U S A. 91 (23):

SOAT2 (972 words) [view diff] exact match in snippet view article find links to article

(2001). "Organization of human ACAT-2 gene and its cell-type-specific promoter activity". Biochem. Biophys. Res. Commun. 282 (2): 580–8. doi:10.1006/bbrc

PLAGL2 (684 words) [view diff] case mismatch in snippet view article find links to article

Yang MC, Weissler JC, Yang YS (2007). "PLAGL2 Translocation and SP-C Promoter Activity – A Cellular Response of Lung Cells to Hypoxia". Biochem. Biophys

Lactase persistence (7,340 words) [view diff] exact match in snippet view article find links to article

with lactase persistence interacts with Oct-1 and stimulates lactase promoter activity in vitro". Human Molecular Genetics. 14 (24): 3945–3953. doi:10.1093/hmg/ddi418

Procyclin (339 words) [view diff] exact match in snippet view article find links to article

unusually small alpha-amanitin-resistant transcription unit: PARP promoter activity assayed by transient DNA transfection of Trypanosoma brucei". Mol

Norepinephrine transporter (3,397 words) [view diff] exact match in snippet view article find links to article

2006). "A polymorphism in the norepinephrine transporter gene alters promoter activity and is associated with attention-deficit hyperactivity disorder".

TBR1 (3,605 words) [view diff] exact match in snippet view article find links to article

found that increased Tbr1/CASK complex expression results in enhanced promoter activity in genes downstream of TBR1 such as NMDAR subunit 2b (NMDAR2b), glycine

FOLR2 (785 words) [view diff] exact match in snippet view article find links to article

folate-binding protein expressed in human placenta. Identification of promoter activity in a G-rich SP1 site linked with the tandemly repeated GGAAG motif

Monoamine oxidase A (4,627 words) [view diff] exact match in snippet view article find links to article

behavior in adolescence and young adulthood: associations and MAOA promoter activity". European Journal of Human Genetics. 16 (5): 626–34. doi:10.1038/sj

OAZ1 (863 words) [view diff] exact match in snippet view article find links to article

PMID 12359729. Ike A, Yamada S, Tanaka H, et al. (2003). "Structure and promoter activity of the gene encoding ornithine decarboxylase antizyme expressed exclusively

CLDN2 (1,030 words) [view diff] exact match in snippet view article find links to article

Cdx-related transcriptional activation in the regulation of the claudin-2 promoter activity". Biochem. Biophys. Res. Commun. 314 (4): 1001–7. doi:10.1016/j.bbrc

MBD1 (1,240 words) [view diff] exact match in snippet view article find links to article

addition, variants with three CXXC domains also repress unmethylated promoter activity. MBD1 and MBD2 map very close to each other on chromosome 18q21. MBD1

NME3 (982 words) [view diff] exact match in snippet view article find links to article

Druck T, Huebner K, Calabretta B (March 1997). "Gene structure, promoter activity, and chromosomal location of the DR-nm23 gene, a related member of

MMP3 (3,031 words) [view diff] exact match in snippet view article find links to article

diseases characterized by insufficient MMP-3 expression due to a lower promoter activity of the 6A allele, such as progressive coronary atherosclerosis. The

Transcription (biology) (6,780 words) [view diff] exact match in snippet view article

Viales RR, Furlong EE (January 2018). "The degree of enhancer or promoter activity is reflected by the levels and directionality of eRNA transcription"

TFPI2 (992 words) [view diff] exact match in snippet view article find links to article

Kamei S, Kazama Y, Kuijper JL, et al. (2001). "Genomic structure and promoter activity of the human tissue factor pathway inhibitor-2 gene". Biochim. Biophys

Transgelin (955 words) [view diff] exact match in snippet view article find links to article

gene, assignment of the gene to chromosome 11, and repression of the promoter activity by cytosine DNA methylation". J. Biochem. 122 (1): 157–67. doi:10

ERRFI1 (932 words) [view diff] exact match in snippet view article find links to article

"Rat gene 33: analysis of its structure, messenger RNA and basal promoter activity". Nucleic Acids Research. 17 (16): 6651–67. doi:10.1093/nar/17.16

PPP2R4 (1,121 words) [view diff] exact match in snippet view article find links to article

phosphotyrosine phosphatase activator gene: Yin Yang 1 is essential for core promoter activity". Biochem. J. 344 (3): 755–63. doi:10.1042/0264-6021:3440755. PMC 1220697

Gene expression (9,242 words) [view diff] exact match in snippet view article find links to article

Males M, Viales RR, et al. (January 2018). "The degree of enhancer or promoter activity is reflected by the levels and directionality of eRNA transcription"

Bioluminescence (8,013 words) [view diff] case mismatch in snippet view article find links to article

GUS/Luciferase Fusion Reporter for Plant Gene Trapping and for Assay of Promoter Activity with Luciferin-Dependent Control of the Reporter Protein Stability"

Folate receptor 1 (1,733 words) [view diff] exact match in snippet view article find links to article

three clustered Sp1-binding sites with initiator region for basal promoter activity". Biochemistry. 34 (31): 9951–61. doi:10.1021/bi00031a018. PMID 7632694

LNCaP (1,754 words) [view diff] exact match in snippet view article find links to article

mRNA, all of which are highly expressed by osteoblasts. Osteoblast promoter activity is also higher in C4-2B cells when compared to LNCaP, as indicated

Glucokinase (5,668 words) [view diff] exact match in snippet view article find links to article

Horvath K, et al. (February 1994). "Analysis of upstream glucokinase promoter activity in transgenic mice and identification of glucokinase in rare neuroendocrine

Microphthalmia-associated transcription factor (4,822 words) [view diff] exact match in snippet view article find links to article

domain of MITF. When expressed together, both MAZR and MITF increase promoter activity of the mMCP-6 gene. MAZR and MITF together transactivate the mMCP-6

Myc (6,709 words) [view diff] exact match in snippet view article find links to article

c-Myc-induced human telomerase reverse transcriptase gene (hTERT) promoter activity in breast cancer". The Journal of Biological Chemistry. 277 (23):

Nuclear receptor co-repressor 2 (3,233 words) [view diff] exact match in snippet view article find links to article

in Notch intracellular domains is critical for regulation of HES promoter activity". Mechanisms of Development. 104 (1–2): 3–20. doi:10.1016/S0925-4773(01)00373-2

Shope papilloma virus (1,944 words) [view diff] exact match in snippet view article find links to article

the viral cycle's late stage. In the upper epithelial layers, the promoter activity is altered during the virus’ production. E4 proteins are expressed

PDCD5 (988 words) [view diff] exact match in snippet view article find links to article

the human programmed cell death 5 gene 5' regulatory region affect promoter activity and the susceptibility of chronic myelogenous leukemia in Chinese

IGFBP3 (4,717 words) [view diff] exact match in snippet view article find links to article

Organization of the human chromosomal gene and demonstration of promoter activity". The Journal of Biological Chemistry. 265 (21): 12642–12649. doi:10

Thromboxane receptor (5,651 words) [view diff] exact match in snippet view article find links to article

TXA2 analogs. SNP variant -4684T was associated with reduced gene promoter activity in the TBXA2R gene and an increased incidence of developing aspirin-induced

Involucrin (1,482 words) [view diff] exact match in snippet view article find links to article

proximal and distal AP1 sites to mediate phorbol ester effects on promoter activity". The Journal of Biological Chemistry. 270 (21): 12614–22. doi:10

Enhancer (genetics) (5,914 words) [view diff] exact match in snippet view article

Males M, Viales RR, et al. (January 2018). "The degree of enhancer or promoter activity is reflected by the levels and directionality of eRNA transcription"

Curli (1,701 words) [view diff] exact match in snippet view article find links to article

N-terminal receiver domain. Since CsgD must be present for csgBA promoter activity, it is therefore suggested that regulators of CsgD expression also

Antisocial personality disorder (13,234 words) [view diff] exact match in snippet view article find links to article

behavior in adolescence and young adulthood: associations and MAOA promoter activity". European Journal of Human Genetics. 16 (5): 626–34. doi:10.1038/sj

Enhancer RNA (3,549 words) [view diff] exact match in snippet view article find links to article

Viales RR, Furlong EE (January 2018). "The degree of enhancer or promoter activity is reflected by the levels and directionality of eRNA transcription"

Sex hormone-binding globulin (4,584 words) [view diff] exact match in snippet view article find links to article

Hammond GL (September 2001). "Human sex hormone-binding globulin promoter activity is influenced by a (TAAAA)n repeat element within an Alu sequence"

Vrille (gene) (1,110 words) [view diff] exact match in snippet view article

sequence of E4BP4, and it does recognize the E4BP4 site. E4BP4 represses promoter activity in per1, per2, and osteoblasts, suggesting its role as a negative

Transcriptional regulation (6,343 words) [view diff] exact match in snippet view article find links to article

Viales RR, Furlong EE (January 2018). "The degree of enhancer or promoter activity is reflected by the levels and directionality of eRNA transcription"

AMP-activated protein kinase (7,058 words) [view diff] exact match in snippet view article find links to article

response element (CRE) are essential for contraction-induced PGC-1α promoter activity. LKB1 knockout mice show a decrease in PGC-1α, as well as mitochondrial

Histone H2A.Z (1,232 words) [view diff] exact match in snippet view article find links to article

WM (1996). "An upstream region of the H2AZ gene promoter modulates promoter activity in different cell types". Biochim. Biophys. Acta. 1305 (1–2): 59–62

ACAT1 (2,322 words) [view diff] exact match in snippet view article find links to article

101-bp DNA fragment immediately upstream from the cap site that has promoter activity. The human ACAT1 gene produces a chimeric mRNA through trans-splicing

Patrizia Casaccia (2,607 words) [view diff] exact match in snippet view article find links to article

Casaccia-Bonnefil P. p27(Kip1) enhances myelin basic protein gene promoter activity. Journal of Neuroscience Research. 67: 100–5. PMID 11754085 DOI: 10

ENOD40 (1,920 words) [view diff] exact match in snippet view article find links to article

Umehara Y, Katinakis P, Stougaard J, Spaink HP (2005). "Analysis of promoter activity of the early nodulin Enod40 in Lotus japonicus". Mol Plant Microbe

PON1 (2,003 words) [view diff] exact match in snippet view article find links to article

activity compared to the 55M allele. The -108C allele has greater promoter activity than the -108T allele which results in different serum activities

POU2AF1 (1,482 words) [view diff] exact match in snippet view article find links to article

novel B cell-specific coactivator that stimulates immunoglobulin promoter activity through association with octamer-binding proteins". Cell. 80 (3):

SPI1 (1,741 words) [view diff] exact match in snippet view article find links to article

Zhao SJ, Clark RA (July 1997). "PU.1 is essential for p47(phox) promoter activity in myeloid cells". The Journal of Biological Chemistry. 272 (28):

Duffy antigen system (9,574 words) [view diff] exact match in snippet view article find links to article

with a single T to C substitution at nucleotide -33, impairing the promoter activity in erythroid cells by disrupting a binding site for the GATA1 erythroid

Bruno Lemaitre (1,351 words) [view diff] exact match in snippet view article find links to article

Coen, D. (1991-05-15). "P regulatory products repress in vivo the P promoter activity in P-lacZ fusion genes". Proceedings of the National Academy of Sciences

Arachidonate 5-lipoxygenase (7,553 words) [view diff] exact match in snippet view article find links to article

region including the Sp1/Egr-1 sites may be critical for basal 5-LO promoter activity. Cells primarily involved in regulating inflammation, allergy, and

NDRG1 (2,179 words) [view diff] exact match in snippet view article find links to article

expression. These effect is mediated indirectly by decreasing its promoter activity. As reviewed by Kovacevic et al., NDRG1 is a potent, iron-regulated

NDRG1 (2,179 words) [view diff] exact match in snippet view article find links to article

expression. These effect is mediated indirectly by decreasing its promoter activity. As reviewed by Kovacevic et al., NDRG1 is a potent, iron-regulated

Induced pluripotent stem cell (10,491 words) [view diff] exact match in snippet view article find links to article

Rex1, and Nanog, were demethylated in iPSCs, demonstrating their promoter activity and the active promotion and expression of pluripotency-associated

Bone morphogenetic protein 4 (5,478 words) [view diff] exact match in snippet view article find links to article

"Antiestrogens specifically up-regulate bone morphogenetic protein-4 promoter activity in human osteoblastic cells". Mol. Endocrinol. 14 (5): 623–33. doi:10

VHb (hemoglobin) (2,344 words) [view diff] exact match in snippet view article

(1990-07-25). "Study of Vitreoscilla globin(vgb) gene expression and promoter activity in E. Coli through transcriptional fusion". Nucleic Acids Research

BRCA1 (14,645 words) [view diff] exact match in snippet view article find links to article

c-Myc-induced human telomerase reverse transcriptase gene (hTERT) promoter activity in breast cancer". J. Biol. Chem. 277 (23): 20965–73. doi:10.1074/jbc

Syndecan-4 (2,088 words) [view diff] exact match in snippet view article find links to article

Sugiura I, Hamaguchi M, Saito H (1997). "Structural organization and promoter activity of the human ryudocan gene". J. Biochem. 119 (5): 979–84. doi:10.1093/oxfordjournals

HLA-F (4,439 words) [view diff] exact match in snippet view article find links to article

Martin MA, Singer DS (May 1993). "Repression of MHC class I gene promoter activity by two-exon Tat of HIV". Science. 260 (5112): 1320–1322. Bibcode:1993Sci

SATB1 (3,024 words) [view diff] exact match in snippet view article find links to article

(2004). "SATB1 makes a complex with p300 and represses gp91(phox) promoter activity". Microbiology and Immunology. 47 (10): 803–811. doi:10.1111/j.1348-0421

Human endogenous retrovirus-W (4,805 words) [view diff] exact match in snippet view article find links to article

assay, HERV-Ws that have incomplete LTR's were still found to have promoter activity. This suggests that the transcription of HERVs can be activated not

MFN2 (3,260 words) [view diff] exact match in snippet view article find links to article

Fernández-Pascual S, Sancho A, Naon D, Vila-Caballer M, et al. (April 2012). "The promoter activity of human Mfn2 depends on Sp1 in vascular smooth muscle cells". Cardiovascular

Bacteriophage P2 (2,994 words) [view diff] exact match in snippet view article find links to article

substitutions, this dyad symmetry has been shown to be essential for promoter activity. Moreover, the late genes of P2 can also be activated by the δ proteins

KaiC (3,377 words) [view diff] exact match in snippet view article find links to article

would cause arrhythmicity in the circadian clock and reduce kaiBC promoter activity. KaiC was later found to have both autokinase and autophosphatase

Bioreporter (1,843 words) [view diff] exact match in snippet view article find links to article

light produced by the luciferase is directly proportional to the promoter activity. In addition to studying the promoters, firefly luciferase assays

Human genetic resistance to malaria (9,634 words) [view diff] exact match in snippet view article find links to article

carrying a single nucleotide mutation (DARC 46 T → C), which impairs promoter activity by disrupting a binding site for the hGATA1 erythroid lineage transcription

RCCX (3,370 words) [view diff] exact match in snippet view article find links to article

(August 2004). "Detection of retroviral antisense transcripts and promoter activity of the HERV-K(C4) insertion in the MHC class III region". Immunogenetics

Cancer epigenetics (12,530 words) [view diff] exact match in snippet view article find links to article

to the promoter region of DNA repair gene BRCA1 and inhibits BRCA1 promoter activity. They also showed that while only 11% of breast tumors had hypermethylation

G-quadruplex (11,903 words) [view diff] exact match in snippet view article find links to article

hypersensitive element of the PDGF-A promoter and modulation of PDGF-A promoter activity by TMPyP4". Nucleic Acids Research. 35 (22): 7698–713. doi:10.1093/nar/gkm538

Susan Golden (2,901 words) [view diff] exact match in snippet view article find links to article

three kai genes; Inactivation of any single kai gene reduced kaiBC-promoter activity and abolished the circadian rhythm of expression of KaiA and KaiB

Skewed X-inactivation (3,773 words) [view diff] exact match in snippet view article find links to article

elucidated at this time, although research does point towards decreased promoter activity as a result of the mutation being a major part of the process. Secondary

Multiple Epidermal Growth Factor-like Domains 8 (3,523 words) [view diff] exact match in snippet view article find links to article

activator depending on both promoter and cell type context; represses promoter activity of SOCS1 and SOCS3 and thus, may regulate cytokine signaling pathways

Eukaryote hybrid genome (11,196 words) [view diff] exact match in snippet view article find links to article

addition to altering gene products if inserted into a gene, also alter promoter activity for genes if inserted upstream of the coding regions, or may induce