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Enhancer (genetics)
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In genetics, an enhancer is a short (50–1500 bp) region of DNA that can be bound by proteins (activators) to increase the likelihood that transcriptionActivator (genetics) (1,959 words) [view diff] exact match in snippet view article
will be complementary to the surface features of the specific DNA regulatory sequence it was designed to bind to. The complementary interactions betweenExpression cassette (370 words) [view diff] exact match in snippet view article find links to article
cassette is a distinct component of vector DNA consisting of a gene and regulatory sequence to be expressed by a transfected cell. In each successful transformationTransgene (3,583 words) [view diff] exact match in snippet view article find links to article
few main parts. The transgene must contain a promoter, which is a regulatory sequence that will determine where and when the transgene is active, an exonSLC39A11 (382 words) [view diff] exact match in snippet view article find links to article
the SOX9 region in human and Fugu rubripes: conservation of short regulatory sequence elements within large intergenic regions". Genomics. 78 (1–2): 73–82Upstream activating sequence (1,197 words) [view diff] exact match in snippet view article find links to article
activating sequence or upstream activation sequence (UAS) is a cis-acting regulatory sequence found in yeast like Saccharomyces cerevisiae. It is distinct fromPolydactyly in stem-tetrapods (993 words) [view diff] exact match in snippet view article find links to article
limb-specific enhancer called the ZRS (zone of polarizing region activity regulatory sequence) that is located approximately 1 Mb upstream of the coding sequenceCCDC138 (1,124 words) [view diff] exact match in snippet view article find links to article
factors that have been predicted by Genomatix that binds to the regulatory sequence of the CCDC138 gene. CCDC138 has been identified as one of the manyYeastract (472 words) [view diff] case mismatch in snippet view article find links to article
the promoter and coding regions for Yeast genes were obtained from Regulatory Sequence Analysis Tools (RSAT). All the information in YEASTRACT is updatedTranscriptional regulation (6,351 words) [view diff] exact match in snippet view article find links to article
undergoing up to 100-fold increased expression due to such a cis-regulatory sequence. These cis-regulatory sequences include enhancers, silencers, insulatorsSON (gene) (2,293 words) [view diff] exact match in snippet view article
SON gene binds to a specific DNA sequence upstream of the upstream regulatory sequence of the core promoter and second enhancer of human hepatitis B virusEukaryotic translation (1,940 words) [view diff] exact match in snippet view article find links to article
mRNAs can have different translation rates due to the presence of regulatory sequence elements. This has been shown to be important in a variety of settingsFusion gene (1,928 words) [view diff] exact match in snippet view article find links to article
misregulation of the expression of a gene now under the control of the cis-regulatory sequence of another gene. If it happens in coding sequences, gene fusion causeRecBCD (2,079 words) [view diff] exact match in snippet view article find links to article
Kowalczykowski SC (April 1993). "The recombination hotspot Chi is a regulatory sequence that acts by attenuating the nuclease activity of the E. coli RecBCDHBV RNA encapsidation signal epsilon (323 words) [view diff] case mismatch in snippet view article find links to article
M301069200. PMID 12851401. Page for HBV RNA encapsidation signal epsilon at Rfam HBVRegDB Hepatitis B Virus HBV Regulatory Sequence Database (HBVRegDB) v t eSilkie (1,866 words) [view diff] case mismatch in snippet view article find links to article
shown to be a SNP in a regulator of the SHH gene, called the ZPA Regulatory Sequence (ZRS). This causes ectopic SHH expression in the anterior of theList of gene prediction software (1,833 words) [view diff] exact match in snippet view article find links to article
Pierre; Thieffry, Denis; van Helden, Jacques (2018-05-02). "RSAT 2018: regulatory sequence analysis tools 20th anniversary". Nucleic Acids Research. 46 (W1):Histone H2A (2,081 words) [view diff] exact match in snippet view article find links to article
The greatest differences were observed in core histone gene cis-regulatory sequence motifs and associated protein factors. Variability in gene sequenceYY1 (1,909 words) [view diff] exact match in snippet view article find links to article
"Binding of the ubiquitous nuclear transcription factor YY1 to a cis regulatory sequence in the human LINE-1 transposable element". Human Molecular GeneticsGATA4 (2,325 words) [view diff] exact match in snippet view article find links to article
(1988). "An erythrocyte-specific DNA-binding factor recognizes a regulatory sequence common to all chicken globin genes". Proc. Natl. Acad. Sci. U.S.ALimb development (4,234 words) [view diff] case mismatch in snippet view article find links to article
snake evolution. In particular, many studies have focused on the ZPA Regulatory Sequence (ZRS) - the enhancer of the Sonic Hedgehog gene (Shh). This long-rangeThomas C. Südhof (2,089 words) [view diff] exact match in snippet view article find links to article
when inserted in a viral promoter. This domain, known as a sterol regulatory sequence, directly participates in the regulation of sterol biosynthesis.Acheiropodia (2,110 words) [view diff] exact match in snippet view article find links to article
present, they help an enhancer called ZRS (zone of polarizing activity regulatory sequence), which is found in intron 5 of the LMBR1 gene, interact with theStein Aerts (1,513 words) [view diff] exact match in snippet view article find links to article
(2005-07-01). "TOUCAN 2: the all-inclusive open source workbench for regulatory sequence analysis". Nucleic Acids Research. 33 (Web Server issue): W393–396C18orf63 (1,805 words) [view diff] exact match in snippet view article find links to article
Betaglobin. Transcription factors of interest predicted to bind to the regulatory sequence include p53 tumor suppressors, SRY testis determining factors, Y-boxFunctional genomics (4,013 words) [view diff] exact match in snippet view article find links to article
Ghandi M, Lee D, Mohammad-Noori M, Beer MA (July 2014). "Enhanced regulatory sequence prediction using gapped k-mer features". PLOS Computational BiologyHuman genome (10,017 words) [view diff] exact match in snippet view article find links to article
from the ENCODE project give that 20 or more of the genome is gene regulatory sequence. Some types of non-coding DNA are genetic "switches" that do notMamL-1 domain (783 words) [view diff] exact match in snippet view article find links to article
Aster JC (August 2006). "Identification of a conserved negative regulatory sequence that influences the leukemogenic activity of NOTCH1". Mol. Cell.Snake (15,216 words) [view diff] case mismatch in snippet view article find links to article
associated with DNA mutations in the Zone of Polarizing Activity Regulatory Sequence (ZRS), a regulatory region of the sonic hedgehog gene which is criticallyLolium arundinaceum (2,746 words) [view diff] exact match in snippet view article find links to article
alkaloid gene clusters across fungal endophytes: predicting the co-regulatory sequence motifs and the evolutionary history". Fungal Genetics and BiologyLINE1 (2,837 words) [view diff] exact match in snippet view article find links to article
"Binding of the ubiquitous nuclear transcription factor YY1 to a cis regulatory sequence in the human LINE-1 transposable element". Human Molecular GeneticsGATA1 (5,512 words) [view diff] exact match in snippet view article find links to article
1988). "An erythrocyte-specific DNA-binding factor recognizes a regulatory sequence common to all chicken globin genes". Proceedings of the NationalIndex of biochemistry articles (2,471 words) [view diff] exact match in snippet view article find links to article
resonance - NMR - nuclear protein - nucleic acid - nucleic acid regulatory sequence - nucleic acid repetitive sequence - nucleic acid sequence homologyPolysyndactyly (1,644 words) [view diff] exact match in snippet view article find links to article
Primarily, mutations are found in the zone of polarizing activity regulatory sequence, or ZRS, that controls the expression of SHH in developing limbsEpigenome (3,801 words) [view diff] exact match in snippet view article find links to article
inter-individual differences in DNA methylation are mainly determined by cis-regulatory sequence polymorphisms, probably involving mutations in TFBSs (TranscriptionMichael Behe (6,301 words) [view diff] case mismatch in snippet view article find links to article
(November 2008). "Waiting for Two Mutations: With Applications to Regulatory Sequence Evolution and the Limits of Darwinian Evolution". Genetics. 180 (3):Apolipoprotein B (4,892 words) [view diff] exact match in snippet view article find links to article
the edited nucleoside and this mooring sequence. There is also a regulatory sequence 3′ to the editing site. The active site of ApoBEC-1, the catalyticNeurofibromin (5,736 words) [view diff] exact match in snippet view article find links to article
splicing are commonly seen and these are often substitutions in the regulatory sequence. Exonic mutations can lead to deletion of an entire exon, or a fragmentLoline alkaloid (2,807 words) [view diff] exact match in snippet view article find links to article
alkaloid gene clusters across fungal endophytes: predicting the co-regulatory sequence motifs and the evolutionary history". Fungal Genetics and BiologyPINK1 (2,677 words) [view diff] exact match in snippet view article find links to article
transmembrane sequence, a Ser/Thr kinase domain, and a C-terminal regulatory sequence. The protein has been found to localize to the outer membrane ofFamilial opposable triphalangeal thumbs duplication (1,410 words) [view diff] exact match in snippet view article find links to article
Wilkie, Andrew O. M. (2008-08-15). "A variant in the sonic hedgehog regulatory sequence (ZRS) is associated with triphalangeal thumb and deregulates expressionEpigenetics of autism (6,263 words) [view diff] exact match in snippet view article find links to article
The imprinted genes of 15q11-13 are under the control of a common regulatory sequence, the imprinting control region (ICR). The ICR is a differentiallyPURA (4,047 words) [view diff] exact match in snippet view article find links to article
between Pur-alpha, the HIV-1 protein, Tat, and a Pur-alpha-binding regulatory sequence in JCV DNA. Pur-alpha acts by altering both replication and geneGlossary of cellular and molecular biology (M–Z) (24,991 words) [view diff] exact match in snippet view article
codons that contains a start codon and a stop codon. operator A regulatory sequence within an operon, typically located between the promoter sequenceRNA-targeting small molecule drugs (4,401 words) [view diff] exact match in snippet view article find links to article
stem-loop RNA. They identified a hit compound that was selective for the regulatory sequence with micromolar binding affinity. In 2011, Butcher and colleagues