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Cytolysin
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used by certain bacteria, such as Listeria monocytogenes, to disrupt the phagosome membrane of macrophages and escape into the cytoplasm of the cell. TheSYT11 (512 words) [view diff] exact match in snippet view article find links to article
recycling endosome postsynaptic density plasma membrane cell body axon early phagosome excitatory synapse neuron projection terminal bouton phagocytic vesicleIntracellular digestion (535 words) [view diff] exact match in snippet view article find links to article
(or phagosome) fuses with a lysosome containing hydrolytic enzymes to form a phagolysosome; the pathogens or food particles within the phagosome are thenSYT7 (553 words) [view diff] exact match in snippet view article find links to article
phagocytic vesicle membrane plasma membrane lysosomal membrane early phagosome dendrite soma axon terminus axon neuron projection exocytic vesicle hippocampalAntigen processing (1,763 words) [view diff] exact match in snippet view article find links to article
Mycobacterium tuberculosis inhibits phagosome-endosome fusion, thus avoiding being destroyed by the harsh environment of the phagosome. ICP47 from some herpesvirusRAB14 (752 words) [view diff] exact match in snippet view article find links to article
PMID 11076863. Garin J, Diez R, Kieffer S, et al. (2001). "The phagosome proteome: insight into phagosome functions". J. Cell Biol. 152 (1): 165–80. doi:10.1083/jcbPhosphatidylmyo-inositol mannosides (287 words) [view diff] exact match in snippet view article find links to article
3-kinase and Rab5 effectors in phagosomal biogenesis and mycobacterial phagosome maturation arrest. J. Cell Biol. 154:631–644. Kaplan, G., R. R. GandhiListeriosis (4,381 words) [view diff] exact match in snippet view article find links to article
then resides in phagocytic vacuoles, or phagosomes, until it enters the cytoplasm by disrupting the phagosome membrane. Within the cytoplasm, the bacteriaRAB7A (2,315 words) [view diff] exact match in snippet view article find links to article
metabolism endosome to lysosome transport phagosome acidification autophagy lipid catabolic process phagosome maturation early endosome to late endosomeEEA1 (646 words) [view diff] exact match in snippet view article find links to article
"Cutting edge: Mycobacterium tuberculosis blocks Ca2+ signaling and phagosome maturation in human macrophages via specific inhibition of sphingosinePTPN9 (680 words) [view diff] exact match in snippet view article find links to article
phosphatase MEG2 is expressed by human neutrophils. Localization to the phagosome and activation by polyphosphoinositides". J. Biol. Chem. 277 (4): 2620–8RAB31 (433 words) [view diff] exact match in snippet view article find links to article
endosome membrane phagocytic cup early phagosome membrane Biological process receptor internalization phagosome maturation cellular response to insulinATP6V0D2 (160 words) [view diff] exact match in snippet view article find links to article
ion transport ion transmembrane transport regulation of macroautophagy phagosome acidification vacuolar transport vacuolar acidification transport Sources:AmigoAPPL2 (415 words) [view diff] exact match in snippet view article find links to article
ruffle plasma membrane cytoplasmic vesicle vesicle early phagosome ruffle membrane early phagosome membrane macropinosome phagocytic vesicle membrane cellVomocytosis (1,549 words) [view diff] exact match in snippet view article find links to article
PMID 17084701. S2CID 11639313. Alvarez M, Casadevall A (November 2006). "Phagosome extrusion and host-cell survival after Cryptococcus neoformans phagocytosisRespiratory burst (2,555 words) [view diff] exact match in snippet view article find links to article
redox centre, which transfers electrons from cytosolic NADPH to O2 in the phagosome. 2O2 + NADPH —> 2O2•– + NADP+ + H+ The superoxide can then spontaneouslyMitochondria associated membranes (1,416 words) [view diff] exact match in snippet view article find links to article
have markers, the auto-phagosome marker ATG14, and the auto-phagosome-formation marker ATG5, until the formation of auto-phagosome is complete. WhereasUNC13B (1,188 words) [view diff] exact match in snippet view article find links to article
membrane synapse cell junction cytoplasm Golgi apparatus membrane early phagosome terminal bouton calyx of Held presynaptic active zone ribbon synapse presynapseEntamoeba gingivalis (594 words) [view diff] exact match in snippet view article find links to article
through its dense core in the middle, formed by a central point encircled by a circular halo and surrounded by bigger phagosomes inside a greyish cytoplasm.Mycobacterium marinum (574 words) [view diff] exact match in snippet view article find links to article
to person. The bacteria invade macrophages, preventing the fusion of phagosome-lysosome and replicating inside. A rare case of human infection was detectedRAB34 (568 words) [view diff] exact match in snippet view article find links to article
nucleolus Biological process antigen processing and presentation phagosome-lysosome fusion phagosome maturation lysosome localization macropinocytosis proteinRab (G-protein) (1,327 words) [view diff] exact match in snippet view article
droplets, golgi, endoplasmic reticulum RAB20 Golgi, mitochondria, early phagosome, early endosome RAB23 Plasma membrane RAB25 Small-scale transport, promoterATP6V1C2 (250 words) [view diff] exact match in snippet view article find links to article
ion transmembrane transport ion transport transferrin transport regulation of macroautophagy phagosome acidification transport Sources:Amigo / QuickGORoyal Society Africa Prize (573 words) [view diff] exact match in snippet view article find links to article
africanum 2019: Henry Mwandumba for his novel work in description of the TB phagosome in HIV infected alveolar macrophages and his leadership in the CollegeATP6V1E2 (466 words) [view diff] exact match in snippet view article find links to article
pathway ion transmembrane transport ion transport transferrin transport regulation of macroautophagy phagosome acidification Sources:Amigo / QuickGOATP6V0A4 (735 words) [view diff] exact match in snippet view article find links to article
transmembrane transport ATP synthesis coupled proton transport regulation of pH phagosome acidification transport proton transmembrane transport Sources:Amigo /Antibody opsonization (641 words) [view diff] exact match in snippet view article find links to article
phagocytic cell, until the particle is contained in a membrane-bound vacuole (phagosome) within the cell. The pathogen is subsequently destroyed following intracellularATP6V1G3 (633 words) [view diff] exact match in snippet view article find links to article
transport insulin receptor signaling pathway ion transmembrane transport ion transport transferrin transport phagosome acidification Sources:Amigo / QuickGOBiological membrane (2,215 words) [view diff] exact match in snippet view article find links to article
membranes); peroxisome; vacuole; cytoplasmic granules; cell vesicles (phagosome, autophagosome, clathrin-coated vesicles, COPI-coated and COPII-coatedATP6V0A2 (838 words) [view diff] exact match in snippet view article find links to article
response ATP synthesis coupled proton transport regulation of macroautophagy phagosome acidification cellular iron ion homeostasis cellular response to increasedRAB7B (411 words) [view diff] exact match in snippet view article find links to article
interferon-gamma intracellular protein transport endosome to lysosome transport Rab protein signal transduction phagosome-lysosome fusion Sources:Amigo / QuickGOATP6V1E1 (723 words) [view diff] exact match in snippet view article find links to article
ion transport ion transmembrane transport regulation of macroautophagy phagosome acidification transport proton transmembrane transport Sources:Amigo /ATP6V1H (889 words) [view diff] exact match in snippet view article find links to article
ion transport ion transmembrane transport regulation of macroautophagy phagosome acidification regulation of catalytic activity viral process vacuolarUNC93B1 (538 words) [view diff] exact match in snippet view article find links to article
receptor binding Cellular component integral component of membrane early phagosome Golgi membrane endosome lysosome phagocytic vesicle endoplasmic reticulumSLAMF8 (268 words) [view diff] exact match in snippet view article find links to article
involved in inflammatory response negative regulation of monocyte chemotaxis phagosome acidification negative regulation of neutrophil migration negative regulationSNX3 (580 words) [view diff] exact match in snippet view article find links to article
Cellular component cytoplasm cytosol endosome early endosome membrane early phagosome retromer complex early endosome phagocytic vesicle extracellular exosomeATP6V1A (703 words) [view diff] exact match in snippet view article find links to article
transmembrane transport ATP metabolic process regulation of macroautophagy phagosome acidification cellular iron ion homeostasis cellular response to increasedATP6V0C (806 words) [view diff] exact match in snippet view article find links to article
ion transmembrane transport viral process regulation of macroautophagy phagosome acidification neutrophil degranulation transport proton transmembraneATP6V1B2 (757 words) [view diff] exact match in snippet view article find links to article
transmembrane transport ATP metabolic process regulation of macroautophagy phagosome acidification transport proton transmembrane transport Sources:Amigo /Toll-like receptor 7 (1,424 words) [view diff] exact match in snippet view article find links to article
integral component of membrane Golgi membrane cytoplasmic vesicle early phagosome endosome receptor complex phagocytic vesicle membrane lysosome endoplasmicATP6V0B (660 words) [view diff] exact match in snippet view article find links to article
insulin receptor signaling pathway ion transport transferrin transport proton transmembrane transport phagosome acidification Sources:Amigo / QuickGOATP6V0D1 (667 words) [view diff] exact match in snippet view article find links to article
development cell projection organization regulation of macroautophagy phagosome acidification cilium assembly vacuolar transport vacuolar acidificationNatural resistance-associated macrophage protein 1 (1,025 words) [view diff] exact match in snippet view article find links to article
intracellular pathogens: the Nramp1 protein is recruited to the membrane of the phagosome". The Journal of Experimental Medicine. 185 (4): 717–30. doi:10.1084/jemSPG11 (571 words) [view diff] exact match in snippet view article find links to article
synaptic vesicle transport axo-dendritic transport lysosome organization phagosome-lysosome fusion involved in apoptotic cell clearance walking behaviorATP6V1D (680 words) [view diff] exact match in snippet view article find links to article
organization protein localization to cilium regulation of macroautophagy phagosome acidification neutrophil degranulation cilium assembly transport protonCross-presentation (2,159 words) [view diff] exact match in snippet view article find links to article
The peptides can then be loaded onto MHC I binding grooves within the phagosome. It is unclear whether the MHC I molecule is being exported from the endoplasmicCoxiella burnetii (1,970 words) [view diff] exact match in snippet view article find links to article
autophagosomes, and lysosomes containing acid phosphatase fuse with the nascent phagosome to form early PV, which fosters the transition from SCV to LCV. ResultantlyATP6V1G1 (714 words) [view diff] exact match in snippet view article find links to article
ion transport ion transmembrane transport regulation of macroautophagy phagosome acidification cellular iron ion homeostasis cellular response to increasedATP6V1F (791 words) [view diff] exact match in snippet view article find links to article
insulin receptor signaling pathway ion transport transferrin transport phagosome acidification ion transmembrane transport transport proton transmembraneATP6V0E1 (763 words) [view diff] exact match in snippet view article find links to article
transmembrane transport regulation of macroautophagy proton transmembrane transport transmembrane transport phagosome acidification Sources:Amigo / QuickGORAB38 (450 words) [view diff] exact match in snippet view article find links to article
to membrane platelet dense granule organization organelle organization phagosome acidification endosome to melanosome transport protein transport melanosomeATP6V1C1 (814 words) [view diff] exact match in snippet view article find links to article
ion transport ion transmembrane transport regulation of macroautophagy phagosome acidification transport proton transmembrane transport Sources:Amigo /ATP6V1B1 (883 words) [view diff] exact match in snippet view article find links to article
inner ear morphogenesis regulation of macroautophagy regulation of pH phagosome acidification transport proton transmembrane transport renal water homeostasisHLA-DO (1,174 words) [view diff] exact match in snippet view article find links to article
2005). "Spatial separation of HLA-DM/HLA-DR interactions within MIIC and phagosome-induced immune escape". Immunity. 22 (2): 221–33. doi:10.1016/S0960-9822(06)00414-3Inflammation (9,751 words) [view diff] exact match in snippet view article find links to article
been implicated to traffic the endocytosed phagosome to intracellular lysosomes, where fusion of the phagosome and the lysosome produces a phagolysosomeFluoProbes (357 words) [view diff] exact match in snippet view article find links to article
Retrieved 2010-03-04. Article Savina A. ; Cell 126, 205–218, July 14, 2006 (Phagosome Neutrality in Host Defense) "Lightning technology from Innova BioSciences"Retina (9,299 words) [view diff] exact match in snippet view article find links to article
Retrieved 23 February 2023. "Diagrammatic representation of disc shedding and phagosome retrieval into the pigment epithelial cell". Archived from the originalMyeloperoxidase (1,879 words) [view diff] exact match in snippet view article find links to article
Hampton MB, Kettle AJ, Winterbourn CC (Nov 1998). "Inside the neutrophil phagosome: oxidants, myeloperoxidase, and bacterial killing". Blood. 92 (9): 3007–17Steven J. Fliesler (1,459 words) [view diff] exact match in snippet view article find links to article
improved therapeutic intervention. Molecules. 2018; 23(10). Compromised phagosome maturation underlies RPE pathology in cell culture and whole animal modelsATPase, H+ transporting, lysosomal V0 subunit a1 (711 words) [view diff] exact match in snippet view article find links to article
proton transport regulation of macroautophagy vacuolar acidification phagosome acidification neutrophil degranulation transport Sources:Amigo / QuickGOPIK3C3 (901 words) [view diff] exact match in snippet view article find links to article
PMID 12551992. Vergne I, Chua J, Deretic V (2003). "Tuberculosis toxin blocking phagosome maturation inhibits a novel Ca2+/calmodulin-PI3K hVPS34 cascade". J. ExpEuglena gracilis (1,009 words) [view diff] exact match in snippet view article find links to article
outermost are derived from the plasma membrane of the alga (third) and the phagosome of the host (fourth). Microalgae are considered a possible source forSebastian Amigorena (368 words) [view diff] exact match in snippet view article find links to article
regulatory T cells. Guermonprez P, Saveanu L... Amigorena S (2003). ER-phagosome fusion defines an MHC class I cross-presentation compartment in dendriticToll-like receptor 9 (2,590 words) [view diff] exact match in snippet view article find links to article
component of membrane endosome endoplasmic reticulum membrane membrane early phagosome Golgi membrane plasma membrane extracellular region basolateral plasmaGAPVD1 (794 words) [view diff] exact match in snippet view article find links to article
2008). "Imaging of Rab5 activity identifies essential regulators for phagosome maturation". Nature. 453 (7192): 241–5. Bibcode:2008Natur.453..241K. doi:10Cryptococcus neoformans (3,380 words) [view diff] exact match in snippet view article find links to article
PMC 4001551. PMID 24743149. Alvarez, M; Casadevall, A (7 November 2006). "Phagosome extrusion and host-cell survival after Cryptococcus neoformans phagocytosisCandida albicans (9,973 words) [view diff] exact match in snippet view article find links to article
yeast-to-hyphal transition within the acidic macrophage phagosome. This initially causes phagosome membrane distension which eventually leads to phagosomalTuberculosis (16,894 words) [view diff] exact match in snippet view article find links to article
macrophage and stored temporarily in a membrane-bound vesicle called a phagosome. The phagosome then combines with a lysosome to create a phagolysosome. In theRAB5A (1,473 words) [view diff] exact match in snippet view article find links to article
membrane clathrin-coated vesicle membrane early endosome membrane early phagosome postsynaptic early endosome anchored component of synaptic vesicle membraneIntracellular transport (1,474 words) [view diff] exact match in snippet view article find links to article
a cell engulfs a solid particle to form an internal vesicle called a phagosome. However, many of these processes have an intracellular component. PhagocytosisTyrosine-protein kinase SYK (2,083 words) [view diff] exact match in snippet view article find links to article
extrinsic component of cytoplasmic side of plasma membrane nucleus early phagosome B cell receptor complex plasma membrane T cell receptor complex protein-containingAPPL1 (1,118 words) [view diff] exact match in snippet view article find links to article
nucleus early endosome ruffle plasma membrane cytoplasmic vesicle early phagosome macropinosome intracellular vesicle cell projection phagocytic vesicleMannose receptor (3,688 words) [view diff] exact match in snippet view article find links to article
receptor directs Mycobacterium tuberculosis lipoarabinomannan-mediated phagosome biogenesis". Journal of Experimental Medicine. 202 (7): 987–99. doi:10ATP6V1G2 (1,782 words) [view diff] exact match in snippet view article find links to article
transport ion transmembrane transport insulin receptor signaling pathway proton transmembrane transport phagosome acidification Sources:Amigo / QuickGOTCIRG1 (2,202 words) [view diff] exact match in snippet view article find links to article
population proliferation ATP synthesis coupled proton transport macroautophagy phagosome acidification neutrophil degranulation transport proton transmembraneTRPV2 (2,673 words) [view diff] exact match in snippet view article find links to article
process known as phagocytosis. In macrophages TRPV2 recruitment toward the phagosome is regulated by PI3k signaling, protein kinase C, akt kinase, and SrcIntracellular pH (1,895 words) [view diff] exact match in snippet view article find links to article
Additionally, fluorescence microscopy techniques have indicated that phagosomes also have a relatively low internal pH. Since these are both degradativeLegionella pneumophila (4,350 words) [view diff] exact match in snippet view article find links to article
correlation between an LPS with a high molecular-weight and the inhibition of phagosome-lysosome fusion. L. pneumophila produces pili of varying lengths. TheCaspase 1 (2,398 words) [view diff] exact match in snippet view article find links to article
by the NLRP3 inflammasome regulates the NADPH oxidase NOX2 to control phagosome function". Nature Immunology. 14 (6): 543–53. doi:10.1038/ni.2595. PMC 3708594Nanoshell (1,715 words) [view diff] exact match in snippet view article find links to article
phagocytes engulf the nanoshells through the cell membrane to form an internal phagosome, or macrophage. After this it is shuttled into a cell and enzymes areRoberta Gottlieb (2,108 words) [view diff] exact match in snippet view article find links to article
how simvastatin induces autophagic flux to restore cerulein-impaired phagosome-lysosome fusion in acute pancreatitis, and also discussed the role ofCaspase 11 (1,388 words) [view diff] exact match in snippet view article find links to article
In addition, association with the actin cytoskeleton surrounding the phagosome contributes to lysosome acidification. Caspase-11 (EC 3.4.22.64, CASP-11)Stimulator of interferon genes (2,748 words) [view diff] exact match in snippet view article find links to article
shown to activate type I interferon through STING. Perforation of the phagosome membrane mediated by ESX1 secretion system allows extracellular mycobacterialAlveolar macrophage (3,910 words) [view diff] exact match in snippet view article find links to article
response. Following internalization, the microbe is enclosed in a vesicular phagosome which then undergoes fusion with primary or secondary lysosomes, formingCeramide kinase (1,895 words) [view diff] exact match in snippet view article find links to article
altering the lipid raft structure via C-1-P production, contributing to phagosome formation in polymorphonuclear leukocytes. CERK has also been found toYossef Av-Gay (552 words) [view diff] exact match in snippet view article find links to article
tyrosine phosphatase (PtpA) excludes host vacuolar-H+–ATPase to inhibit phagosome acidification". Proceedings of the National Academy of Sciences. 108 (48):Nonspecific immune cell (1,478 words) [view diff] exact match in snippet view article find links to article
specific immune responses. When a phagocytic cell engulfs bacteria, a phagosome is formed around it and the entire complex is ultimately trafficked toOutline of cell biology (4,376 words) [view diff] exact match in snippet view article find links to article
engulfing solid particles into the cell membrane to form an internal phagosome, or "food vacuole." Tonicity – This is a measure of the effective osmoticDictyostelium discoideum (4,796 words) [view diff] exact match in snippet view article find links to article
discoideum, after entry into amoebae, in a phagosome the fusion with lysosomes is blocked and these unmatured phagosomes are surrounded by host cell organellesBerghia (1,813 words) [view diff] exact match in snippet view article find links to article
Berghia ingest the anemone, the immature nematocysts are encased within a phagosome and are allowed to mature in the cnidosacs. When startled or attackedMannose receptor C-type 1 (679 words) [view diff] exact match in snippet view article find links to article
receptor directs Mycobacterium tuberculosis lipoarabinomannan-mediated phagosome biogenesis". J. Exp. Med. 202 (7): 987–99. doi:10.1084/jem.20051239. PMC 2213176Jennifer Stow (1,598 words) [view diff] exact match in snippet view article find links to article
Phagocytosis: Measuring Engulfment and Internalization", Phagocytosis and Phagosomes, Methods in Molecular Biology, vol. 1519, Springer New York, pp. 201–214Bafilomycin (4,672 words) [view diff] exact match in snippet view article find links to article
SM, Levitz SM, Harrison TS (August 2000). "Chloroquine and the fungal phagosome". Current Opinion in Microbiology. 3 (4): 349–53. doi:10.1016/S1369-5274(00)00102-8Leishmania donovani (4,436 words) [view diff] exact match in snippet view article find links to article
PMID 15471704. Lodge, R; Descoteaux, A (2008). "Leishmania Invasion and Phagosome Biogenesis". Molecular Mechanisms of Parasite Invasion. Subcellular BiochemistryVisceral leishmaniasis (9,209 words) [view diff] exact match in snippet view article find links to article
S2CID 22659332. Lodge R, Descoteaux, A (2008). "Leishmania Invasion and Phagosome Biogenesis". Molecular Mechanisms of Parasite Invasion. Subcellular BiochemistryHistophilus somni (3,433 words) [view diff] exact match in snippet view article find links to article
"Histophilus somni Survives in Bovine Macrophages by Interfering with Phagosome-Lysosome Fusion but Requires IbpA for Optimal Serum Resistance". InfectionArturo Casadevall (3,649 words) [view diff] exact match in snippet view article find links to article
09.032. PMID 17084701. Alvarez, M; Casadevall, A (7 November 2006). "Phagosome extrusion and host-cell survival after Cryptococcus neoformans phagocytosisPhagoptosis (1,318 words) [view diff] exact match in snippet view article find links to article
the surface of a (target) cell activate phagocytic receptors on a phagocyte, inducing uptake into a phagosome, where the cell is killed and digested.Lipid droplet (3,584 words) [view diff] exact match in snippet view article find links to article
C. N.; Dvorak, Ann M.; Chitnis, Chetan E. (5 July 2012). "Lipid Body–Phagosome Interaction in Macrophages during Infectious Diseases: Host Defense orFind-me signals (3,524 words) [view diff] exact match in snippet view article find links to article
Hengartner, Michael O.; Ravichandran, Kodi S. (May 2008). "A pathway for phagosome maturation during engulfment of apoptotic cells". Nature Cell BiologyNeutrophil swarming (3,376 words) [view diff] exact match in snippet view article find links to article
vacuole. The engulfing process begins with a bacteria, then turns into a phagosome when it being to form a vacuole, and lastly becomes a phagolysosome that